Protein kinase

Overview
NameProtein kinase
Smed IDSMED30000664
Length (bp)4789
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein kinase (SMED30000664) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein kinase (SMED30000664) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein kinase (SMED30000664) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein kinase (SMED30000664) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30000664

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30000664h1SMcG0019191 SmedASXL_013879SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30000664h1SMcG0019191 SmedASXL_013879SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30000664h1SMcG0019191 SmedASXL_010248SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30000664h1SMcG0019191 SmedASXL_010248SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30000664h1SMcG0019191 Contig35520newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30000664h1SMcG0019191 Contig35520uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30000664h1SMcG0019191 Contig20332uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30000664h1SMcG0019191 Contig20332newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
reproductive organSMED30000664h1SMcG0019191 Contig35520newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30000664h1SMcG0019191 Contig35520uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
epidermisSMED30000664h1SMcG0019191 dd_Smed_v4_6431_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Protein kinase vs. Ensembl Human
Match: TLK1 (tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841])

HSP 1 Score: 501.516 bits (1290), Expect = 1.571e-159
Identity = 265/523 (50.67%), Postives = 357/523 (68.26%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS---------------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQIT 3866
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ ++RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K+  KRKP +                K K     +  P + PN        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN SW  +KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S  AK FIRRC  YRKE R DV QL ND YL P  +  +S     + G     LT  P    SS IT
Sbjct:  152 DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHMAG-----LTASPTPPSSSIIT 669
[Close]
BLAST of Protein kinase vs. Ensembl Human
Match: TLK1 (tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841])

HSP 1 Score: 502.671 bits (1293), Expect = 2.435e-159
Identity = 265/523 (50.67%), Postives = 357/523 (68.26%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS---------------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQIT 3866
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ ++RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K+  KRKP +                K K     +  P + PN        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN SW  +KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S  AK FIRRC  YRKE R DV QL ND YL P  +  +S     + G     LT  P    SS IT
Sbjct:  200 DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHMAG-----LTASPTPPSSSIIT 717
[Close]
BLAST of Protein kinase vs. Ensembl Human
Match: TLK1 (tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841])

HSP 1 Score: 503.827 bits (1296), Expect = 4.214e-159
Identity = 265/523 (50.67%), Postives = 357/523 (68.26%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS---------------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQIT 3866
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ ++RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K+  KRKP +                K K     +  P + PN        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN SW  +KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S  AK FIRRC  YRKE R DV QL ND YL P  +  +S     + G     LT  P    SS IT
Sbjct:  248 DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHMAG-----LTASPTPPSSSIIT 765
[Close]
BLAST of Protein kinase vs. Ensembl Human
Match: TLK2 (tousled like kinase 2 [Source:HGNC Symbol;Acc:HGNC:11842])

HSP 1 Score: 496.508 bits (1277), Expect = 1.642e-158
Identity = 263/495 (53.13%), Postives = 351/495 (70.91%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP--------ASEKTKQTGKQKGSPE---LEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNP-EGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPS 3815
            +L ++++ + K  E+ K+   +   +  K L+++S+ E+ A R++   ++L LG F + R GA + E+W++G  +Q+L K+++ I  QR+E E+++KM  KRKP        A+ + KQ   +    E   L   E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++A+S+I Q+V+AL+YLN+ K PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD +N  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYG+KPFG+N +Q DIL  NTIL+A  + FP  P ++  AK FIRRC  YRKE R DV QL  D YL P   ++ SV  +   G +
Sbjct:   95 DLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLP--HIRKSVSTSSPAGAA 587
[Close]
BLAST of Protein kinase vs. Ensembl Human
Match: TLK1 (tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841])

HSP 1 Score: 503.056 bits (1294), Expect = 1.862e-158
Identity = 265/523 (50.67%), Postives = 357/523 (68.26%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS---------------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQIT 3866
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ ++RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K+  KRKP +                K K     +  P + PN        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN SW  +KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S  AK FIRRC  YRKE R DV QL ND YL P  +  +S     + G     LT  P    SS IT
Sbjct:  269 DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHMAG-----LTASPTPPSSSIIT 786
[Close]
BLAST of Protein kinase vs. Ensembl Celegans
Match: tlk-1 (Serine/threonine-protein kinase tousled-like 1 [Source:UniProtKB/Swiss-Prot;Acc:P34314])

HSP 1 Score: 465.692 bits (1197), Expect = 7.638e-144
Identity = 241/528 (45.64%), Postives = 338/528 (64.02%), Query Frame = 3 
Query: 2328 NQNNESSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP------------ASEKTKQTGKQKGS-------------PELEPNEFYWQA-----EIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILL---CNNGEIKITDFGLSKIF---PDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVL 3803
            N  N   V  +   +E+  +++E    +N   +     ++E + + L+ ++++ER+A R++   +   +G FK+ R G  + ++W +G  + +++KK + I  +R+E      +  KRKP             + +    G Q  +             PE EP E  +Q      EI+ +R+ ++ KEE DL  E ERL++E+  H+RE+KR  NE AS+F D  +L+ RYL+L+LLGKGGFSEV K FD+E+  +VACKIH +N  W ++KK +Y+KHA+RE  IHK LDH RIV+ +D+  IDN +FCTVLEY  GNDLDFYLKQN+ I E++A+S+I Q+VSAL YLN++  PIIHYDLKP NILL     +G IKITDFGLSKI     DDH    G+ELTSQ AGTYWYLPPE F+    PP I+ KVDVWS+GVIFYQ +YGKKPFGN++TQ  IL  NTI+ AR ++FPS P++S  A+DFIRRC  YRKE R DVF+L   +  +P+  ++ SV  ++L
Sbjct:  340 NPQNADEVAKMNRIIEDHRRQIEELNSKNSLERRKNEASKETIKRLLIDKNQIERKALRDKTAADSPRIGCFKTTRTGDSFRDQWVDGWAFAEMDKKTEQINAERNEIASASALLKKRKPLGIGKEPKRPQAVNSQNDSNGMQPSTSSNTNGDDAIFRRPE-EPKEIQYQEYIELDEIYKLRREHLRKEETDLSMEKERLEKEKQHHVRELKRASNESASQFNDHRLLHKRYLMLNLLGKGGFSEVWKAFDIEENRYVACKIHHVNKDWKEEKKANYVKHAMREKDIHKSLDHCRIVKQYDLLTIDNHSFCTVLEYVPGNDLDFYLKQNRSISEKEARSIIMQVVSALVYLNEKSTPIIHYDLKPANILLESGNTSGAIKITDFGLSKIMEGESDDHD--LGIELTSQFAGTYWYLPPETFIVP--PPKITCKVDVWSIGVIFYQCIYGKKPFGNDLTQQKILEYNTIINAREVSFPSKPQVSSAAQDFIRRCLQYRKEDRADVFELAKHELFRPRGAIRASVAGSLL 862
[Close]
BLAST of Protein kinase vs. Ensembl Celegans
Match: tlk-1 (Serine/threonine-protein kinase tousled-like 1 [Source:UniProtKB/Swiss-Prot;Acc:P34314])

HSP 1 Score: 464.537 bits (1194), Expect = 2.174e-143
Identity = 240/523 (45.89%), Postives = 335/523 (64.05%), Query Frame = 3 
Query: 2328 NQNNESSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP------------ASEKTKQTGKQKGS-------------PELEPNEFYWQA-----EIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILL---CNNGEIKITDFGLSKIF---PDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSV 3788
            N  N   V  +   +E+  +++E    +N   +     ++E + + L+ ++++ER+A R++   +   +G FK+ R G  + ++W +G  + +++KK + I  +R+E      +  KRKP             + +    G Q  +             PE EP E  +Q      EI+ +R+ ++ KEE DL  E ERL++E+  H+RE+KR  NE AS+F D  +L+ RYL+L+LLGKGGFSEV K FD+E+  +VACKIH +N  W ++KK +Y+KHA+RE  IHK LDH RIV+ +D+  IDN +FCTVLEY  GNDLDFYLKQN+ I E++A+S+I Q+VSAL YLN++  PIIHYDLKP NILL     +G IKITDFGLSKI     DDH    G+ELTSQ AGTYWYLPPE F+    PP I+ KVDVWS+GVIFYQ +YGKKPFGN++TQ  IL  NTI+ AR ++FPS P++S  A+DFIRRC  YRKE R DVF+L   +  +P+  ++ SV
Sbjct:  354 NPQNADEVAKMNRIIEDHRRQIEELNSKNSLERRKNEASKETIKRLLIDKNQIERKALRDKTAADSPRIGCFKTTRTGDSFRDQWVDGWAFAEMDKKTEQINAERNEIASASALLKKRKPLGIGKEPKRPQAVNSQNDSNGMQPSTSSNTNGDDAIFRRPE-EPKEIQYQEYIELDEIYKLRREHLRKEETDLSMEKERLEKEKQHHVRELKRASNESASQFNDHRLLHKRYLMLNLLGKGGFSEVWKAFDIEENRYVACKIHHVNKDWKEEKKANYVKHAMREKDIHKSLDHCRIVKQYDLLTIDNHSFCTVLEYVPGNDLDFYLKQNRSISEKEARSIIMQVVSALVYLNEKSTPIIHYDLKPANILLESGNTSGAIKITDFGLSKIMEGESDDHD--LGIELTSQFAGTYWYLPPETFIVP--PPKITCKVDVWSIGVIFYQCIYGKKPFGNDLTQQKILEYNTIINAREVSFPSKPQVSSAAQDFIRRCLQYRKEDRADVFELAKHELFRPRGAIRASV 871
[Close]
BLAST of Protein kinase vs. Ensembl Celegans
Match: tlk-1 (Serine/threonine-protein kinase tousled-like 1 [Source:UniProtKB/Swiss-Prot;Acc:P34314])

HSP 1 Score: 466.848 bits (1200), Expect = 2.262e-143
Identity = 241/528 (45.64%), Postives = 338/528 (64.02%), Query Frame = 3 
Query: 2328 NQNNESSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP------------ASEKTKQTGKQKGS-------------PELEPNEFYWQA-----EIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILL---CNNGEIKITDFGLSKIF---PDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVL 3803
            N  N   V  +   +E+  +++E    +N   +     ++E + + L+ ++++ER+A R++   +   +G FK+ R G  + ++W +G  + +++KK + I  +R+E      +  KRKP             + +    G Q  +             PE EP E  +Q      EI+ +R+ ++ KEE DL  E ERL++E+  H+RE+KR  NE AS+F D  +L+ RYL+L+LLGKGGFSEV K FD+E+  +VACKIH +N  W ++KK +Y+KHA+RE  IHK LDH RIV+ +D+  IDN +FCTVLEY  GNDLDFYLKQN+ I E++A+S+I Q+VSAL YLN++  PIIHYDLKP NILL     +G IKITDFGLSKI     DDH    G+ELTSQ AGTYWYLPPE F+    PP I+ KVDVWS+GVIFYQ +YGKKPFGN++TQ  IL  NTI+ AR ++FPS P++S  A+DFIRRC  YRKE R DVF+L   +  +P+  ++ SV  ++L
Sbjct:  421 NPQNADEVAKMNRIIEDHRRQIEELNSKNSLERRKNEASKETIKRLLIDKNQIERKALRDKTAADSPRIGCFKTTRTGDSFRDQWVDGWAFAEMDKKTEQINAERNEIASASALLKKRKPLGIGKEPKRPQAVNSQNDSNGMQPSTSSNTNGDDAIFRRPE-EPKEIQYQEYIELDEIYKLRREHLRKEETDLSMEKERLEKEKQHHVRELKRASNESASQFNDHRLLHKRYLMLNLLGKGGFSEVWKAFDIEENRYVACKIHHVNKDWKEEKKANYVKHAMREKDIHKSLDHCRIVKQYDLLTIDNHSFCTVLEYVPGNDLDFYLKQNRSISEKEARSIIMQVVSALVYLNEKSTPIIHYDLKPANILLESGNTSGAIKITDFGLSKIMEGESDDHD--LGIELTSQFAGTYWYLPPETFIVP--PPKITCKVDVWSIGVIFYQCIYGKKPFGNDLTQQKILEYNTIINAREVSFPSKPQVSSAAQDFIRRCLQYRKEDRADVFELAKHELFRPRGAIRASVAGSLL 943
[Close]
BLAST of Protein kinase vs. Ensembl Celegans
Match: tlk-1 (Serine/threonine-protein kinase tousled-like 1 [Source:UniProtKB/Swiss-Prot;Acc:P34314])

HSP 1 Score: 465.692 bits (1197), Expect = 5.286e-143
Identity = 240/523 (45.89%), Postives = 335/523 (64.05%), Query Frame = 3 
Query: 2328 NQNNESSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP------------ASEKTKQTGKQKGS-------------PELEPNEFYWQA-----EIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILL---CNNGEIKITDFGLSKIF---PDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSV 3788
            N  N   V  +   +E+  +++E    +N   +     ++E + + L+ ++++ER+A R++   +   +G FK+ R G  + ++W +G  + +++KK + I  +R+E      +  KRKP             + +    G Q  +             PE EP E  +Q      EI+ +R+ ++ KEE DL  E ERL++E+  H+RE+KR  NE AS+F D  +L+ RYL+L+LLGKGGFSEV K FD+E+  +VACKIH +N  W ++KK +Y+KHA+RE  IHK LDH RIV+ +D+  IDN +FCTVLEY  GNDLDFYLKQN+ I E++A+S+I Q+VSAL YLN++  PIIHYDLKP NILL     +G IKITDFGLSKI     DDH    G+ELTSQ AGTYWYLPPE F+    PP I+ KVDVWS+GVIFYQ +YGKKPFGN++TQ  IL  NTI+ AR ++FPS P++S  A+DFIRRC  YRKE R DVF+L   +  +P+  ++ SV
Sbjct:  421 NPQNADEVAKMNRIIEDHRRQIEELNSKNSLERRKNEASKETIKRLLIDKNQIERKALRDKTAADSPRIGCFKTTRTGDSFRDQWVDGWAFAEMDKKTEQINAERNEIASASALLKKRKPLGIGKEPKRPQAVNSQNDSNGMQPSTSSNTNGDDAIFRRPE-EPKEIQYQEYIELDEIYKLRREHLRKEETDLSMEKERLEKEKQHHVRELKRASNESASQFNDHRLLHKRYLMLNLLGKGGFSEVWKAFDIEENRYVACKIHHVNKDWKEEKKANYVKHAMREKDIHKSLDHCRIVKQYDLLTIDNHSFCTVLEYVPGNDLDFYLKQNRSISEKEARSIIMQVVSALVYLNEKSTPIIHYDLKPANILLESGNTSGAIKITDFGLSKIMEGESDDHD--LGIELTSQFAGTYWYLPPETFIVP--PPKITCKVDVWSIGVIFYQCIYGKKPFGNDLTQQKILEYNTIINAREVSFPSKPQVSSAAQDFIRRCLQYRKEDRADVFELAKHELFRPRGAIRASV 938
[Close]
BLAST of Protein kinase vs. Ensembl Celegans
Match: par-1 (Serine/threonine-protein kinase par-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9TW45])

HSP 1 Score: 111.694 bits (278), Expect = 2.328e-24
Identity = 83/244 (34.02%), Postives = 126/244 (51.64%), Query Frame = 3 
Query: 2877 IDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKI---HELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTE--NGPPTISSKVDVWSVGVIFYQSLYGKKPF-GNNM 3590
            + +  A+R  D  +   +Y +L  +GKG F++V     +     VA KI     LNPS         ++   RE+ I K+LDH  IV+++ V   +   +  VLEY  G ++  YL  +  + E++A++   Q+VSA++YL+ +   IIH DLK  N+LL  +  IKI DFG S  F        G +L +   G+  Y  PE F  +  +GP     +VDVWS+GVI Y  + G  PF G N+
Sbjct:  251 MSSRSAARRNDQDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPS--------SLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYL-VLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKN--IIHRDLKAENLLLDQDMNIKIADFGFSNTF------SLGNKLDT-FCGSPPYAAPELFSGKKYDGP-----EVDVWSLGVILYTLVSGSLPFDGQNL 471
[Close]
BLAST of Protein kinase vs. Ensembl Fly
Match: Tlk (gene:FBgn0283657 transcript:FBtr0299579)

HSP 1 Score: 457.218 bits (1175), Expect = 5.530e-137
Identity = 222/343 (64.72%), Postives = 274/343 (79.88%), Query Frame = 3 
Query: 2748 EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPE-GMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            E+Y   EI  +R+  + KE+ DLQ E E+L+RERNLHIRE+KRI NE+ SRF + P+LNDRYL+L LLGKGGFSEVHK FDL++  +VACK+H+LN  W +DKK +YIKHALRE +IHK LDH R+V+++DVF ID ++FCTVLEYC+G+DLDFYLKQ+K IPER+A+S+I Q+VSAL+YLN+ K P+IHYDLKPGNILL      GEIKITDFGLSK+  D+++NP+ GM+LTSQGAGTYWYLPPECFV    PP ISSKVDVWSVGVIFYQ LYGKKPFG+N +Q  IL  NTIL+A  + F + P +S+ AK FIR C  YRKE R DVF L   +Y++P
Sbjct:  855 EYYEYDEILKLRQNALKKEDADLQLEMEKLERERNLHIRELKRILNEDQSRFNNHPVLNDRYLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRVVKLYDVFEIDANSFCTVLEYCDGHDLDFYLKQHKTIPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSKVMDDENYNPDHGMDLTSQGAGTYWYLPPECFVVGKNPPKISSKVDVWSVGVIFYQCLYGKKPFGHNQSQATILEENTILKATEVQFSNKPTVSNEAKSFIRGCLAYRKEDRMDVFALARHEYIQP 1197

HSP 2 Score: 67.781 bits (164), Expect = 9.388e-11
Identity = 32/98 (32.65%), Postives = 63/98 (64.29%), Query Frame = 3 
Query: 2415 EQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQ 2708
            +Q K +  K  +V+ K L ++S +E++  R++   N+L LGQF + R GA ++E W++G  +Q+L ++++ I  +R+E +++KK   K++PA    K+
Sbjct:  596 DQHKCHIAKCIDVVKKLLKEKSSIEKKEARQKCMQNRLRLGQFVTQRVGATFQENWTDGYAFQELSRRQEEITAEREEIDRQKKQLMKKRPAESGRKR 693
[Close]
BLAST of Protein kinase vs. Ensembl Fly
Match: Tlk (gene:FBgn0283657 transcript:FBtr0333753)

HSP 1 Score: 456.833 bits (1174), Expect = 6.010e-137
Identity = 222/343 (64.72%), Postives = 274/343 (79.88%), Query Frame = 3 
Query: 2748 EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPE-GMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            E+Y   EI  +R+  + KE+ DLQ E E+L+RERNLHIRE+KRI NE+ SRF + P+LNDRYL+L LLGKGGFSEVHK FDL++  +VACK+H+LN  W +DKK +YIKHALRE +IHK LDH R+V+++DVF ID ++FCTVLEYC+G+DLDFYLKQ+K IPER+A+S+I Q+VSAL+YLN+ K P+IHYDLKPGNILL      GEIKITDFGLSK+  D+++NP+ GM+LTSQGAGTYWYLPPECFV    PP ISSKVDVWSVGVIFYQ LYGKKPFG+N +Q  IL  NTIL+A  + F + P +S+ AK FIR C  YRKE R DVF L   +Y++P
Sbjct:  842 EYYEYDEILKLRQNALKKEDADLQLEMEKLERERNLHIRELKRILNEDQSRFNNHPVLNDRYLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRVVKLYDVFEIDANSFCTVLEYCDGHDLDFYLKQHKTIPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSKVMDDENYNPDHGMDLTSQGAGTYWYLPPECFVVGKNPPKISSKVDVWSVGVIFYQCLYGKKPFGHNQSQATILEENTILKATEVQFSNKPTVSNEAKSFIRGCLAYRKEDRMDVFALARHEYIQP 1184

HSP 2 Score: 67.781 bits (164), Expect = 9.203e-11
Identity = 32/98 (32.65%), Postives = 63/98 (64.29%), Query Frame = 3 
Query: 2415 EQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQ 2708
            +Q K +  K  +V+ K L ++S +E++  R++   N+L LGQF + R GA ++E W++G  +Q+L ++++ I  +R+E +++KK   K++PA    K+
Sbjct:  583 DQHKCHIAKCIDVVKKLLKEKSSIEKKEARQKCMQNRLRLGQFVTQRVGATFQENWTDGYAFQELSRRQEEITAEREEIDRQKKQLMKKRPAESGRKR 680
[Close]
BLAST of Protein kinase vs. Ensembl Fly
Match: Tlk (gene:FBgn0283657 transcript:FBtr0345319)

HSP 1 Score: 456.833 bits (1174), Expect = 6.010e-137
Identity = 222/343 (64.72%), Postives = 274/343 (79.88%), Query Frame = 3 
Query: 2748 EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPE-GMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            E+Y   EI  +R+  + KE+ DLQ E E+L+RERNLHIRE+KRI NE+ SRF + P+LNDRYL+L LLGKGGFSEVHK FDL++  +VACK+H+LN  W +DKK +YIKHALRE +IHK LDH R+V+++DVF ID ++FCTVLEYC+G+DLDFYLKQ+K IPER+A+S+I Q+VSAL+YLN+ K P+IHYDLKPGNILL      GEIKITDFGLSK+  D+++NP+ GM+LTSQGAGTYWYLPPECFV    PP ISSKVDVWSVGVIFYQ LYGKKPFG+N +Q  IL  NTIL+A  + F + P +S+ AK FIR C  YRKE R DVF L   +Y++P
Sbjct:  842 EYYEYDEILKLRQNALKKEDADLQLEMEKLERERNLHIRELKRILNEDQSRFNNHPVLNDRYLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRVVKLYDVFEIDANSFCTVLEYCDGHDLDFYLKQHKTIPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSKVMDDENYNPDHGMDLTSQGAGTYWYLPPECFVVGKNPPKISSKVDVWSVGVIFYQCLYGKKPFGHNQSQATILEENTILKATEVQFSNKPTVSNEAKSFIRGCLAYRKEDRMDVFALARHEYIQP 1184

HSP 2 Score: 67.781 bits (164), Expect = 9.203e-11
Identity = 32/98 (32.65%), Postives = 63/98 (64.29%), Query Frame = 3 
Query: 2415 EQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQ 2708
            +Q K +  K  +V+ K L ++S +E++  R++   N+L LGQF + R GA ++E W++G  +Q+L ++++ I  +R+E +++KK   K++PA    K+
Sbjct:  583 DQHKCHIAKCIDVVKKLLKEKSSIEKKEARQKCMQNRLRLGQFVTQRVGATFQENWTDGYAFQELSRRQEEITAEREEIDRQKKQLMKKRPAESGRKR 680
[Close]
BLAST of Protein kinase vs. Ensembl Fly
Match: Tlk (gene:FBgn0283657 transcript:FBtr0299583)

HSP 1 Score: 456.833 bits (1174), Expect = 6.010e-137
Identity = 222/343 (64.72%), Postives = 274/343 (79.88%), Query Frame = 3 
Query: 2748 EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPE-GMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            E+Y   EI  +R+  + KE+ DLQ E E+L+RERNLHIRE+KRI NE+ SRF + P+LNDRYL+L LLGKGGFSEVHK FDL++  +VACK+H+LN  W +DKK +YIKHALRE +IHK LDH R+V+++DVF ID ++FCTVLEYC+G+DLDFYLKQ+K IPER+A+S+I Q+VSAL+YLN+ K P+IHYDLKPGNILL      GEIKITDFGLSK+  D+++NP+ GM+LTSQGAGTYWYLPPECFV    PP ISSKVDVWSVGVIFYQ LYGKKPFG+N +Q  IL  NTIL+A  + F + P +S+ AK FIR C  YRKE R DVF L   +Y++P
Sbjct:  842 EYYEYDEILKLRQNALKKEDADLQLEMEKLERERNLHIRELKRILNEDQSRFNNHPVLNDRYLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRVVKLYDVFEIDANSFCTVLEYCDGHDLDFYLKQHKTIPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSKVMDDENYNPDHGMDLTSQGAGTYWYLPPECFVVGKNPPKISSKVDVWSVGVIFYQCLYGKKPFGHNQSQATILEENTILKATEVQFSNKPTVSNEAKSFIRGCLAYRKEDRMDVFALARHEYIQP 1184

HSP 2 Score: 67.781 bits (164), Expect = 9.203e-11
Identity = 32/98 (32.65%), Postives = 63/98 (64.29%), Query Frame = 3 
Query: 2415 EQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQ 2708
            +Q K +  K  +V+ K L ++S +E++  R++   N+L LGQF + R GA ++E W++G  +Q+L ++++ I  +R+E +++KK   K++PA    K+
Sbjct:  583 DQHKCHIAKCIDVVKKLLKEKSSIEKKEARQKCMQNRLRLGQFVTQRVGATFQENWTDGYAFQELSRRQEEITAEREEIDRQKKQLMKKRPAESGRKR 680
[Close]
BLAST of Protein kinase vs. Ensembl Fly
Match: Tlk (gene:FBgn0283657 transcript:FBtr0299580)

HSP 1 Score: 457.218 bits (1175), Expect = 6.388e-137
Identity = 222/343 (64.72%), Postives = 274/343 (79.88%), Query Frame = 3 
Query: 2748 EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPE-GMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            E+Y   EI  +R+  + KE+ DLQ E E+L+RERNLHIRE+KRI NE+ SRF + P+LNDRYL+L LLGKGGFSEVHK FDL++  +VACK+H+LN  W +DKK +YIKHALRE +IHK LDH R+V+++DVF ID ++FCTVLEYC+G+DLDFYLKQ+K IPER+A+S+I Q+VSAL+YLN+ K P+IHYDLKPGNILL      GEIKITDFGLSK+  D+++NP+ GM+LTSQGAGTYWYLPPECFV    PP ISSKVDVWSVGVIFYQ LYGKKPFG+N +Q  IL  NTIL+A  + F + P +S+ AK FIR C  YRKE R DVF L   +Y++P
Sbjct:  866 EYYEYDEILKLRQNALKKEDADLQLEMEKLERERNLHIRELKRILNEDQSRFNNHPVLNDRYLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRVVKLYDVFEIDANSFCTVLEYCDGHDLDFYLKQHKTIPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSKVMDDENYNPDHGMDLTSQGAGTYWYLPPECFVVGKNPPKISSKVDVWSVGVIFYQCLYGKKPFGHNQSQATILEENTILKATEVQFSNKPTVSNEAKSFIRGCLAYRKEDRMDVFALARHEYIQP 1208

HSP 2 Score: 67.781 bits (164), Expect = 9.412e-11
Identity = 32/98 (32.65%), Postives = 63/98 (64.29%), Query Frame = 3 
Query: 2415 EQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQ 2708
            +Q K +  K  +V+ K L ++S +E++  R++   N+L LGQF + R GA ++E W++G  +Q+L ++++ I  +R+E +++KK   K++PA    K+
Sbjct:  607 DQHKCHIAKCIDVVKKLLKEKSSIEKKEARQKCMQNRLRLGQFVTQRVGATFQENWTDGYAFQELSRRQEEITAEREEIDRQKKQLMKKRPAESGRKR 704
[Close]
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: tlk1a (tousled-like kinase 1a [Source:ZFIN;Acc:ZDB-GENE-071008-2])

HSP 1 Score: 504.212 bits (1297), Expect = 6.592e-160
Identity = 273/547 (49.91%), Postives = 374/547 (68.37%), Query Frame = 3 
Query: 2286 KPATINSSDNAIIHNQNNESSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRK---------------PASEKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHST 3848
            K ATI S+ N  +  +  E  + +L     +L ++++ + K  E+ K+   K   +  K L+++S  E++A RE+   ++L LG F + R GA + E+W++G  +Q+L K+++WI +QR+E E+++K+  KRK               P   KTK     +  P L+P+        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE++S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN +W ++KK++Y KHA RE  IHK+LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD++  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FPS P  S+ AK FIRRC  YRKE R DV QL +D YL P  +             +S S T+ P+ST
Sbjct:  196 KLATIESNKNLDL--EKKEGRIDDLLRANCDLRRQIDEQQKLLEKYKERLNKCITMSKKLLIEKSTQEKQACREKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLVKQQEWIIQQREEIERQRKLLAKRKPPSASSSQSPSTNSEPKQRKTKAVNGSENDPFLKPSLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDSSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLIEQRYAAVKIHQLNKNWREEKKENYHKHACREYRIHKQLDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMTEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDNYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPSKPVASNEAKAFIRRCLAYRKEDRFDVHQLGSDSYLLPHIR------------RASSSGTLAPNST 728
[Close]
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: tlk2 (tousled-like kinase 2 [Source:NCBI gene;Acc:407732])

HSP 1 Score: 501.13 bits (1289), Expect = 3.145e-159
Identity = 271/536 (50.56%), Postives = 367/536 (68.47%), Query Frame = 3 
Query: 2268 HNSENPKPATINSSDNA---------IIHNQNNESSVINLK-GKLENL-------EQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPN-----------------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            H S + KPA+I++   A         +   ++++SS +  K G++++L        ++++ + K  E+ K+   K   +  K L+++S+ E+ A RE+   ++L LG F + R GA + E+W++G  +Q+L K+++ +  QR+E E+++K+  K+KP S        Q   P LEPN                 E++ Q EI  +R  ++ KEE ++Q E ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++A+S+I Q+V+AL+YLN+ + PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD++  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYGKKPFG+N +Q DIL  NTIL+A  + FP  P +S  AK FIRRC  YRKE R DV QL +D YL P
Sbjct:  139 HTSTSHKPASIHTQHRASQSELTMEKLAALESSKSSDLEKKEGRIDDLLRVNCDLRRQIDEQQKMLERCKERLNKCVTMSKKLLIEKSKQEKIACREKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLVKQQERVNGQREEIERQRKLLMKKKPPS------ASQTPPPNLEPNKRKSKSNGAENEMLSLAEYHEQEEIFKLRLGHLKKEEAEIQVELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQVVNALKYLNEIRPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDNYGVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGKKPFGHNQSQQDILQENTILKATEVQFPPKPGVSPEAKAFIRRCLVYRKEDRIDVHQLASDPYLLP 668
[Close]
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: tlk1b (tousled-like kinase 1b [Source:NCBI gene;Acc:326734])

HSP 1 Score: 503.056 bits (1294), Expect = 4.137e-159
Identity = 265/523 (50.67%), Postives = 360/523 (68.83%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRK--------------PASEKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITS 3869
            +L ++++ + K  E+ K+   K   +  K L+++S  E+++ RE+   ++L LG F + R GA Y E+W++G  +Q+L K+++WI +QR+E E+++K+  KRK                  KTK        P L+P+        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE++S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN +W ++KK++Y KHA RE  IHK+LDH RIV+++D F++D D FCTVLE+CEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP+ P  S+ AK FIRRC  YRKE R DV QL +D YL P  +  +          SSG+L   P S   S I S
Sbjct:  243 DLRRQIDEQQKLLERFKERLNKCTTMSKKLLIEKSTQEKQSCREKSMQDRLRLGHFTTVRHGASYSEQWTDGYAFQNLVKQQEWINQQREEIERQRKLLAKRKPPSTPSSQSPTPNESKQRKTKAVNGADNDPFLKPSLPTLLTVAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDSSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLFEQRYAAVKIHQLNKNWREEKKENYHKHACREYRIHKQLDHPRIVKLYDYFSLDTDTFCTVLEFCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPAKPVASNEAKAFIRRCLAYRKEDRFDVHQLGSDSYLLPHMRRSN----------SSGNLQATPASPAPSGIIS 755
[Close]
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: tlk1b (tousled-like kinase 1b [Source:NCBI gene;Acc:326734])

HSP 1 Score: 501.901 bits (1291), Expect = 1.459e-158
Identity = 265/523 (50.67%), Postives = 360/523 (68.83%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRK--------------PASEKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITS 3869
            +L ++++ + K  E+ K+   K   +  K L+++S  E+++ RE+   ++L LG F + R GA Y E+W++G  +Q+L K+++WI +QR+E E+++K+  KRK                  KTK        P L+P+        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE++S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN +W ++KK++Y KHA RE  IHK+LDH RIV+++D F++D D FCTVLE+CEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP+ P  S+ AK FIRRC  YRKE R DV QL +D YL P  +  +          SSG+L   P S   S I S
Sbjct:  256 DLRRQIDEQQKLLERFKERLNKCTTMSKKLLIEKSTQEKQSCREKSMQDRLRLGHFTTVRHGASYSEQWTDGYAFQNLVKQQEWINQQREEIERQRKLLAKRKPPSTPSSQSPTPNESKQRKTKAVNGADNDPFLKPSLPTLLTVAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDSSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLFEQRYAAVKIHQLNKNWREEKKENYHKHACREYRIHKQLDHPRIVKLYDYFSLDTDTFCTVLEFCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPAKPVASNEAKAFIRRCLAYRKEDRFDVHQLGSDSYLLPHMRRSN----------SSGNLQATPASPAPSGIIS 768
[Close]
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: tlk2 (tousled-like kinase 2 [Source:NCBI gene;Acc:407732])

HSP 1 Score: 498.819 bits (1283), Expect = 2.276e-158
Identity = 271/536 (50.56%), Postives = 366/536 (68.28%), Query Frame = 3 
Query: 2268 HNSENPKPATINSSDNA---------IIHNQNNESSVINLK-GKLENL-------EQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPN-----------------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            H S + KPA+I++   A         +   ++++SS +  K G++++L        ++++ + K  E  K+   K   +  K L+++S+ E+ A RE+   ++L LG F + R GA + E+W++G  +Q+L K+++ +  QR+E E+++K+  K+KP S        Q   P LEPN                 E++ Q EI  +R  ++ KEE ++Q E ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++A+S+I Q+V+AL+YLN+ + PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD++  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYGKKPFG+N +Q DIL  NTIL+A  + FP  P +S  AK FIRRC  YRKE R DV QL +D YL P
Sbjct:  139 HTSTSHKPASIHTQHRASQSELTMEKLAALESSKSSDLEKKEGRIDDLLRVNCDLRRQIDEQQKMLEWCKERLNKCVTMSKKLLIEKSKQEKIACREKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLVKQQERVNGQREEIERQRKLLIKKKPPS------ASQTPPPNLEPNKRKSKSNGAENEMLSLAEYHEQEEIFKLRLGHLKKEEAEIQVELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQVVNALKYLNEIRPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDNYGVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGKKPFGHNQSQQDILQENTILKATEVQFPPKPGVSPEAKAFIRRCLVYRKEDRIDVHQLASDPYLLP 668
[Close]
BLAST of Protein kinase vs. Ensembl Xenopus
Match: ccdc89 (coiled-coil domain containing 89 [Source:Xenbase;Acc:XB-GENE-5853491])

HSP 1 Score: 507.294 bits (1305), Expect = 1.696e-162
Identity = 264/515 (51.26%), Postives = 358/515 (69.51%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPE---------------LEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQIT 3866
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ A+RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K   KRKP S  + QT      P+               ++P E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN SW  +KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S+ AK FIRRC  YRKE R DV QL ND YL P  +  +S     + G     L   P +  SS I+
Sbjct:  101 DLRRQIDEQQKILEKYKERLNKCISMSKKLLIEKSTQEKLASREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKQLAKRKPPSSNSSQTPSANSEPKQRKNKAVNGAENDPFVKPTEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSNEAKAFIRRCLAYRKEDRFDVHQLANDAYLLPHMRRSNSSGNLHMSG-----LVASPTTPTSSIIS 610
[Close]
BLAST of Protein kinase vs. Ensembl Xenopus
Match: ccdc89 (coiled-coil domain containing 89 [Source:Xenbase;Acc:XB-GENE-5853491])

HSP 1 Score: 501.516 bits (1290), Expect = 3.019e-162
Identity = 260/490 (53.06%), Postives = 344/490 (70.20%), Query Frame = 3 
Query: 2451 VLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPE---------------LEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQIT 3866
            +L K L+ Q +L   A+RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K   KRKP S  + QT      P+               ++P E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN SW  +KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S+ AK FIRRC  YRKE R DV QL ND YL P  +  +S     + G     L   P +  SS I+
Sbjct:    1 MLSKYLITQEKL---ASREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKQLAKRKPPSSNSSQTPSANSEPKQRKNKAVNGAENDPFVKPTEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSNEAKAFIRRCLAYRKEDRFDVHQLANDAYLLPHMRRSNSSGNLHMSG-----LVASPTTPTSSIIS 482
[Close]
BLAST of Protein kinase vs. Ensembl Xenopus
Match: ccdc89 (coiled-coil domain containing 89 [Source:Xenbase;Acc:XB-GENE-5853491])

HSP 1 Score: 507.679 bits (1306), Expect = 5.772e-162
Identity = 264/515 (51.26%), Postives = 358/515 (69.51%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPE---------------LEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQIT 3866
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ A+RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K   KRKP S  + QT      P+               ++P E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN SW  +KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S+ AK FIRRC  YRKE R DV QL ND YL P  +  +S     + G     L   P +  SS I+
Sbjct:  150 DLRRQIDEQQKILEKYKERLNKCISMSKKLLIEKSTQEKLASREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKQLAKRKPPSSNSSQTPSANSEPKQRKNKAVNGAENDPFVKPTEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSNEAKAFIRRCLAYRKEDRFDVHQLANDAYLLPHMRRSNSSGNLHMSG-----LVASPTTPTSSIIS 659
[Close]
BLAST of Protein kinase vs. Ensembl Xenopus
Match: ccdc89 (coiled-coil domain containing 89 [Source:Xenbase;Acc:XB-GENE-5853491])

HSP 1 Score: 503.442 bits (1295), Expect = 1.059e-159
Identity = 264/523 (50.48%), Postives = 356/523 (68.07%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPN-----------------------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQIT 3866
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ A+RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K   KRKP S  + QT      P+   N                       E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN SW  +KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S+ AK FIRRC  YRKE R DV QL ND YL P  +  +S     + G     L   P +  SS I+
Sbjct:  193 DLRRQIDEQQKILEKYKERLNKCISMSKKLLIEKSTQEKLASREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKQLAKRKPPSSNSSQTPSANSEPKQRKNKAVNGAENDPFVKPSLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSNEAKAFIRRCLAYRKEDRFDVHQLANDAYLLPHMRRSNSSGNLHMSG-----LVASPTTPTSSIIS 710
[Close]
BLAST of Protein kinase vs. Ensembl Xenopus
Match: ccdc89 (coiled-coil domain containing 89 [Source:Xenbase;Acc:XB-GENE-5853491])

HSP 1 Score: 503.442 bits (1295), Expect = 1.069e-159
Identity = 264/523 (50.48%), Postives = 356/523 (68.07%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPN-----------------------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQIT 3866
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ A+RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K   KRKP S  + QT      P+   N                       E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN SW  +KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S+ AK FIRRC  YRKE R DV QL ND YL P  +  +S     + G     L   P +  SS I+
Sbjct:  198 DLRRQIDEQQKILEKYKERLNKCISMSKKLLIEKSTQEKLASREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKQLAKRKPPSSNSSQTPSANSEPKQRKNKAVNGAENDPFVKPSLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSNEAKAFIRRCLAYRKEDRFDVHQLANDAYLLPHMRRSNSSGNLHMSG-----LVASPTTPTSSIIS 715
[Close]
BLAST of Protein kinase vs. Ensembl Mouse
Match: Tlk1 (tousled-like kinase 1 [Source:MGI Symbol;Acc:MGI:2441683])

HSP 1 Score: 506.138 bits (1302), Expect = 3.963e-160
Identity = 266/523 (50.86%), Postives = 358/523 (68.45%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS---------------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQIT 3866
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ ++RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K+  KRKP +                KTK     +  P + PN        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN SW  +KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S  AK FIRRC  YRKE R DV QL ND YL P  +  +S     + G     LT  P    SS IT
Sbjct:  248 DLRRQIDDQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLGKRKPPTANNSQAPATNSEAKQRKTKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHMSG-----LTATPTPPSSSIIT 765
[Close]
BLAST of Protein kinase vs. Ensembl Mouse
Match: Tlk2 (tousled-like kinase 2 (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1346023])

HSP 1 Score: 496.893 bits (1278), Expect = 2.730e-157
Identity = 263/495 (53.13%), Postives = 351/495 (70.91%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP--------ASEKTKQTGKQKGSPE---LEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNP-EGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPS 3815
            +L ++++ + K  E+ K+   +   +  K L+++S+ E+ A R++   ++L LG F + R GA + E+W++G  +Q+L K+++ I  QR+E E+++KM  KRKP        A+ + KQ   +    E   L   E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++A+S+I Q+V+AL+YLN+ K PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD +N  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYG+KPFG+N +Q DIL  NTIL+A  + FP  P ++  AK FIRRC  YRKE R DV QL  D YL P   ++ SV  +   G +
Sbjct:  212 DLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLP--HIRKSVSTSSPAGAA 704
[Close]
BLAST of Protein kinase vs. Ensembl Mouse
Match: Tlk2 (tousled-like kinase 2 (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1346023])

HSP 1 Score: 496.893 bits (1278), Expect = 2.730e-157
Identity = 263/495 (53.13%), Postives = 351/495 (70.91%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP--------ASEKTKQTGKQKGSPE---LEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNP-EGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPS 3815
            +L ++++ + K  E+ K+   +   +  K L+++S+ E+ A R++   ++L LG F + R GA + E+W++G  +Q+L K+++ I  QR+E E+++KM  KRKP        A+ + KQ   +    E   L   E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++A+S+I Q+V+AL+YLN+ K PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD +N  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYG+KPFG+N +Q DIL  NTIL+A  + FP  P ++  AK FIRRC  YRKE R DV QL  D YL P   ++ SV  +   G +
Sbjct:  212 DLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLP--HIRKSVSTSSPAGAA 704
[Close]
BLAST of Protein kinase vs. Ensembl Mouse
Match: Tlk2 (tousled-like kinase 2 (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1346023])

HSP 1 Score: 496.893 bits (1278), Expect = 6.924e-157
Identity = 263/495 (53.13%), Postives = 351/495 (70.91%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP--------ASEKTKQTGKQKGSPE---LEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNP-EGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPS 3815
            +L ++++ + K  E+ K+   +   +  K L+++S+ E+ A R++   ++L LG F + R GA + E+W++G  +Q+L K+++ I  QR+E E+++KM  KRKP        A+ + KQ   +    E   L   E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++A+S+I Q+V+AL+YLN+ K PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD +N  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYG+KPFG+N +Q DIL  NTIL+A  + FP  P ++  AK FIRRC  YRKE R DV QL  D YL P   ++ SV  +   G +
Sbjct:  244 DLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLP--HIRKSVSTSSPAGAA 736
[Close]
BLAST of Protein kinase vs. Ensembl Mouse
Match: Tlk2 (tousled-like kinase 2 (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1346023])

HSP 1 Score: 424.091 bits (1089), Expect = 2.144e-131
Identity = 224/414 (54.11%), Postives = 302/414 (72.95%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP--------ASEKTKQTGKQKGSPE---LEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNP-EGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKK 3572
            +L ++++ + K  E+ K+   +   +  K L+++S+ E+ A R++   ++L LG F + R GA + E+W++G  +Q+L K+++ I  QR+E E+++KM  KRKP        A+ + KQ   +    E   L   E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++A+S+I Q+V+AL+YLN+ K PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD +N  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYG+K
Sbjct:  180 DLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRK 593
[Close]
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q8C0V0|TLK1_MOUSE (Serine/threonine-protein kinase tousled-like 1 OS=Mus musculus OX=10090 GN=Tlk1 PE=1 SV=2)

HSP 1 Score: 506.138 bits (1302), Expect = 2.772e-159
Identity = 266/523 (50.86%), Postives = 358/523 (68.45%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS---------------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQIT 3866
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ ++RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K+  KRKP +                KTK     +  P + PN        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN SW  +KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S  AK FIRRC  YRKE R DV QL ND YL P  +  +S     + G     LT  P    SS IT
Sbjct:  248 DLRRQIDDQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLGKRKPPTANNSQAPATNSEAKQRKTKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHMSG-----LTATPTPPSSSIIT 765
[Close]
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q9UKI8|TLK1_HUMAN (Serine/threonine-protein kinase tousled-like 1 OS=Homo sapiens OX=9606 GN=TLK1 PE=1 SV=2)

HSP 1 Score: 503.827 bits (1296), Expect = 2.024e-158
Identity = 265/523 (50.67%), Postives = 357/523 (68.26%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS---------------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQIT 3866
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ ++RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K+  KRKP +                K K     +  P + PN        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN SW  +KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S  AK FIRRC  YRKE R DV QL ND YL P  +  +S     + G     LT  P    SS IT
Sbjct:  248 DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHMAG-----LTASPTPPSSSIIT 765
[Close]
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q1ECX4|TLK2_DANRE (Serine/threonine-protein kinase tousled-like 2 OS=Danio rerio OX=7955 GN=tlk2 PE=2 SV=2)

HSP 1 Score: 498.819 bits (1283), Expect = 1.718e-157
Identity = 271/536 (50.56%), Postives = 366/536 (68.28%), Query Frame = 3 
Query: 2268 HNSENPKPATINSSDNA---------IIHNQNNESSVINLK-GKLENL-------EQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPN-----------------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            H S + KPA+I++   A         +   ++++SS +  K G++++L        ++++ + K  E  K+   K   +  K L+++S+ E+ A RE+   ++L LG F + R GA + E+W++G  +Q+L K+++ +  QR+E E+++K+  K+KP S        Q   P LEPN                 E++ Q EI  +R  ++ KEE ++Q E ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++A+S+I Q+V+AL+YLN+ + PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD++  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYGKKPFG+N +Q DIL  NTIL+A  + FP  P +S  AK FIRRC  YRKE R DV QL +D YL P
Sbjct:  139 HTSTSHKPASIHTQHRASQSELTMEKLAALESSKSSDLEKKEGRIDDLLRVNCDLRRQIDEQQKMLEWCKERLNKCVTMSKKLLIEKSKQEKIACREKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLVKQQERVNGQREEIERQRKLLIKKKPPS------ASQTPPPNLEPNKRKSKSNGAENEMLSLAEYHEQEEIFKLRLGHLKKEEAEIQVELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQVVNALKYLNEIRPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDNYGVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGKKPFGHNQSQQDILQENTILKATEVQFPPKPGVSPEAKAFIRRCLVYRKEDRIDVHQLASDPYLLP 668
[Close]
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q90ZY6|TLK1B_DANRE (Serine/threonine-protein kinase tousled-like 1-B OS=Danio rerio OX=7955 GN=tlk1b PE=2 SV=1)

HSP 1 Score: 500.745 bits (1288), Expect = 2.278e-157
Identity = 264/523 (50.48%), Postives = 359/523 (68.64%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRK--------------PASEKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITS 3869
            +L ++++ + K  E+ K+   K   +  K L+++S  E+++ RE+   ++L LG F + R GA Y E+W++G  +Q+L K+++WI +QR+E E+++K+  KRK                  KTK        P L+P+        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE++S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN +W ++KK++Y KHA RE  IHK+LDH RIV+++D F++D D FCTVLE+CEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K  IIHYDLKPGNILL +    GEIKITDFGLSKI  DD +  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP+ P  S+ AK FIRRC  YRKE R DV QL +D YL P  +  +          SSG+L   P S   S I S
Sbjct:  243 DLRRQIDEQQKLLERFKERLNKCTTMSKKLLIEKSTQEKQSCREKSMQDRLRLGHFTTVRHGASYSEQWTDGYAFQNLVKQQEWINQQREEIERQRKLLAKRKPSSTPSSQSPTPNESKQRKTKAVNGADNDPFLKPSLPTLLTVAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDSSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLFEQRYAAVKIHQLNKNWREEKKENYHKHACREYRIHKQLDHPRIVKLYDYFSLDTDTFCTVLEFCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPSIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPAKPVASNEAKAFIRRCLAYRKEDRSDVHQLGSDSYLLPHMRRSN----------SSGNLQATPASPAPSGIIS 755
[Close]
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|O55047|TLK2_MOUSE (Serine/threonine-protein kinase tousled-like 2 OS=Mus musculus OX=10090 GN=Tlk2 PE=1 SV=2)

HSP 1 Score: 496.893 bits (1278), Expect = 1.909e-156
Identity = 263/495 (53.13%), Postives = 351/495 (70.91%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP--------ASEKTKQTGKQKGSPE---LEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNP-EGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPS 3815
            +L ++++ + K  E+ K+   +   +  K L+++S+ E+ A R++   ++L LG F + R GA + E+W++G  +Q+L K+++ I  QR+E E+++KM  KRKP        A+ + KQ   +    E   L   E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++A+S+I Q+V+AL+YLN+ K PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD +N  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYG+KPFG+N +Q DIL  NTIL+A  + FP  P ++  AK FIRRC  YRKE R DV QL  D YL P   ++ SV  +   G +
Sbjct:  212 DLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLP--HIRKSVSTSSPAGAA 704
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BLAST of Protein kinase vs. TrEMBL
Match: A0A4E0REU0 (Tousled kinase OS=Fasciola hepatica OX=6192 GN=D915_004052 PE=4 SV=1)

HSP 1 Score: 675.241 bits (1741), Expect = 0.000e+0
Identity = 336/536 (62.69%), Postives = 429/536 (80.04%), Query Frame = 3 
Query: 2343 SSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPE-GMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHS------TQSSQITS---SNHY*SSHVSPLIP 3911
            +++ +++  +  LE+E   + +   ++++  +++REV+ + L+++S LER+ TR+RV  N+L LGQF + RQGAH+EEKW EG ++++L+++RK IE  R+E E++KK WNKRKP+    K+  K KG  E+  +EFY Q EI+D+RK  + KE+K++Q E ERLDRERNLHIREIKRI NE+ASRF+D P+LNDRYL+L+LLGKGGFSEVHKGFDL    +VACK+H+LNP+WP+DKKD+YIKHALREI+IHK L+H RIV+V DVF+ID+DAFCTVLEY EGNDLDF+LKQNK IPER+AKS+ICQ+VSAL+YLN+R+ P+IHYDLKPGNILL +    GEIKITDFGLSK+  DD +NPE GM+LTSQGAGTYWYLPPECF T   PP ISSKVD+WSVGVIFYQ L+G+KPFG+NM+Q DILH N IL ARNI FPS  K+SDGAK+FIR+CCTYRKELRPDVFQLCNDDYLKPKAQLKH++D + LPGP    + VPP S      T +S I++   S+H  S H++   P
Sbjct:  542 ATIESMQRHISELEREAALQRENLIKMQENAQRSREVIRELLIEKSVLERKTTRQRVMENRLRLGQFVTQRQGAHFEEKWIEGSRFKELDQRRKNIELVREEIERKKKQWNKRKPSLGDGKKNSKSKGD-EVSVDEFYEQLEIYDLRKQMLVKEDKEIQMELERLDRERNLHIREIKRIANEDASRFKDHPLLNDRYLLLNLLGKGGFSEVHKGFDLVANRYVACKVHQLNPAWPKDKKDNYIKHALREINIHKTLNHPRIVKVFDVFDIDHDAFCTVLEYSEGNDLDFFLKQNKSIPEREAKSIICQVVSALKYLNERRPPVIHYDLKPGNILLGSGQVAGEIKITDFGLSKLMTDDEYNPETGMDLTSQGAGTYWYLPPECFETGREPPKISSKVDIWSVGVIFYQCLFGRKPFGHNMSQADILHENIILHARNIVFPSSTKVSDGAKEFIRKCCTYRKELRPDVFQLCNDDYLKPKAQLKHNLDTSSLPGP----VGVPPSSCVLPNFTSASGISTLPQSSHISSGHLNSAFP 1072
[Close]
BLAST of Protein kinase vs. TrEMBL
Match: A0A4S2KC97 (Protein kinase domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_011069 PE=4 SV=1)

HSP 1 Score: 674.855 bits (1740), Expect = 0.000e+0
Identity = 332/515 (64.47%), Postives = 417/515 (80.97%), Query Frame = 3 
Query: 2343 SSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPE-GMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITSSN 3875
            +++  L+ K+ +LE EL  + +   +L++   ++REV+ + L+ +S LER+ TR++V  ++L LGQF + RQGAH+EEKW EG ++++LE++RK IE  R+E E++KK WNKRKP     K+  K +G  E+  +EFY Q EI+D+RK  + KE+K++Q E ERLDRERNLHIREIKRI NE+ASRF+D P+LN+RYL+L+LLGKGGFSEVHKGFDL +  +VACK+H+LNP+WP+DKKD+YIKHALREI+IHK L+H RIV+V DVF+ID+DAFCTVLEY EGNDLDF+LKQNK IPER+AKS+ICQ+VSAL+YLN+RK P+IHYDLKPGNILL +    GEIKITDFGLSK+  +D +NPE GM+LTSQGAGTYWYLPPECF T   PP ISSKVD+WSVGVIF+Q L+GKKPFG+NM+Q DILH NTIL ARNI FPS  K+SDGAK+FIR+CCTYRKELRPDVFQLCNDDYLKPKAQLKH++D + LPGP       PP S   S  +S N
Sbjct:  546 ATIETLQRKMADLEHELTFQRETVAKLQESGLRSREVIRELLIDKSTLERKTTRQKVMEDRLRLGQFITQRQGAHFEEKWVEGSRFRELEQRRKNIELVREEIERKKKQWNKRKPTIGDGKKNPKSRGD-EVSVDEFYEQLEIYDLRKQMLVKEDKEIQLELERLDRERNLHIREIKRIANEDASRFKDHPLLNERYLLLNLLGKGGFSEVHKGFDLIENRYVACKVHQLNPAWPKDKKDNYIKHALREINIHKTLNHPRIVKVFDVFDIDHDAFCTVLEYSEGNDLDFFLKQNKSIPEREAKSIICQVVSALKYLNERKPPVIHYDLKPGNILLGSGQVAGEIKITDFGLSKLMTEDEYNPETGMDLTSQGAGTYWYLPPECFETGREPPKISSKVDIWSVGVIFFQCLFGKKPFGHNMSQADILHENTILHARNIVFPSTTKVSDGAKEFIRKCCTYRKELRPDVFQLCNDDYLKPKAQLKHNLDTSTLPGPVGN----PPTSCLLSSYSSGN 1055
[Close]
BLAST of Protein kinase vs. TrEMBL
Match: H2KS66 (Tousled-like kinase OS=Clonorchis sinensis OX=79923 GN=CLF_108292 PE=4 SV=1)

HSP 1 Score: 674.085 bits (1738), Expect = 0.000e+0
Identity = 337/554 (60.83%), Postives = 434/554 (78.34%), Query Frame = 3 
Query: 2247 DVIPFTEHNSENPKPATINSSDNAIIHN-------QNNESSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPE-GMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITSSN 3875
            D++PF+ H+SE    + ++ + + +  +           +++  L+ K+ +LE EL  + +   +L++   ++REV+ + L+ +S LER+ TR++V  ++L LGQF + RQGAH+EEKW EG ++++LE++RK IE  R+E E++KK WNKRKP     K+  K +G  E+  +EFY Q EI+D+RK  + KE+K++Q E ERLDRERNLHIREIKRI NE+ASRF+D P+LN+RYL+L+LLGKGGFSEVHKGFDL +  +VACK+H+LNP+WP+DKKD+YIKHALREI+IHK L+H RIV+V DVF+ID+DAFCTVLEY EGNDLDF+LKQNK IPER+AKS+ICQ+VSAL+YLN+RK P+IHYDLKPGNILL +    GEIKITDFGLSK+  +D +NPE GM+LTSQGAGTYWYLPPECF T   PP ISSKVD+WSVGVIF+Q L+GKKPFG+NM+Q DILH NTIL ARNI FPS  K+SDGAK+FIR+CCTYRKELRPDVFQLCNDDYLKPKAQLKH++D + LPGP       PP S   S  ++ N
Sbjct:  508 DLLPFS-HSSECTDDSVVSVTTSPVKASLVPGAPASTMNATIETLQRKMADLEHELTFQRETVAKLQESGLRSREVIRELLIDKSTLERKTTRQKVMEDRLRLGQFITQRQGAHFEEKWVEGSRFRELEQRRKNIELVREEIERKKKQWNKRKPTIGDGKKNPKSRGD-EVSVDEFYEQLEIYDLRKQMLVKEDKEIQLELERLDRERNLHIREIKRIANEDASRFKDHPLLNERYLLLNLLGKGGFSEVHKGFDLVENRYVACKVHQLNPAWPKDKKDNYIKHALREINIHKTLNHPRIVKVFDVFDIDHDAFCTVLEYSEGNDLDFFLKQNKSIPEREAKSIICQVVSALKYLNERKPPVIHYDLKPGNILLGSGQVAGEIKITDFGLSKLMTEDEYNPETGMDLTSQGAGTYWYLPPECFETGREPPKISSKVDIWSVGVIFFQCLFGKKPFGHNMSQADILHENTILHARNIVFPSTTKVSDGAKEFIRKCCTYRKELRPDVFQLCNDDYLKPKAQLKHNLDTSTLPGPVGN----PPTSCLLSSYSTGN 1055
[Close]
BLAST of Protein kinase vs. TrEMBL
Match: A0A1S8X1E3 (Kinase domain protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_03585 PE=4 SV=1)

HSP 1 Score: 673.7 bits (1737), Expect = 0.000e+0
Identity = 332/515 (64.47%), Postives = 417/515 (80.97%), Query Frame = 3 
Query: 2343 SSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPE-GMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITSSN 3875
            +++  L+ K+ +LE EL  + +   +L++   ++REV+ + L+ +S LER+ TR++V  ++L LGQF + RQGAH+EEKW EG ++++LE++RK IE  R+E E++KK WNKRKP     K+  K +G  E+  +EFY Q EI+D+RK  + KE+K++Q E ERLDRERNLHIREIKRI NE+ASRF+D P+LN+RYL+L+LLGKGGFSEVHKGFDL +  +VACK+H+LNP+WP+DKKD+YIKHALREI+IHK L+H RIV+V DVF+ID+DAFCTVLEY EGNDLDF+LKQNK IPER+AKS+ICQ+VSAL+YLN+RK P+IHYDLKPGNILL +    GEIKITDFGLSK+  +D +NPE GM+LTSQGAGTYWYLPPECF T   PP ISSKVD+WSVGVIF+Q L+GKKPFG+NM+Q DILH NTIL ARNI FPS  K+SDGAK+FIR+CCTYRKELRPDVFQLCNDDYLKPKAQLKH++D + LPGP       PP S   S  +S N
Sbjct:  546 ATIETLQRKMADLEHELTFQRETVAKLQESGLRSREVIRELLIDKSTLERKTTRQKVMEDRLRLGQFITQRQGAHFEEKWVEGSRFRELEQRRKNIELVREEIERKKKQWNKRKPTIGDGKKNPKSRGD-EVSVDEFYEQLEIYDLRKQMLVKEDKEIQLELERLDRERNLHIREIKRIANEDASRFKDHPLLNERYLLLNLLGKGGFSEVHKGFDLVENRYVACKVHQLNPAWPKDKKDNYIKHALREINIHKTLNHPRIVKVFDVFDIDHDAFCTVLEYSEGNDLDFFLKQNKSIPEREAKSIICQVVSALKYLNERKPPVIHYDLKPGNILLGSGQVAGEIKITDFGLSKLMTEDEYNPETGMDLTSQGAGTYWYLPPECFETGREPPKISSKVDIWSVGVIFFQCLFGKKPFGHNMSQADILHENTILHARNIVFPSTTKVSDGAKEFIRKCCTYRKELRPDVFQLCNDDYLKPKAQLKHNLDTSTLPGPVGN----PPTSCLLSSYSSGN 1055
[Close]
BLAST of Protein kinase vs. TrEMBL
Match: A0A5J4NI59 (Tousled-like kinase OS=Paragonimus westermani OX=34504 GN=DEA37_0008769 PE=4 SV=1)

HSP 1 Score: 672.544 bits (1734), Expect = 0.000e+0
Identity = 332/515 (64.47%), Postives = 414/515 (80.39%), Query Frame = 3 
Query: 2343 SSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPE-GMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITSSN 3875
            ++V +L+ +L + E EL  +     +L++   K+R+ + + L+++S LER+ TR++V  N+L LGQF + RQGAH+EEKW EG ++++L+++RK IE  R+E E++KK WNKRKP     K+  K KG  E+  +EFY Q EI D+RK  + KE+K++Q E ERLDRERNLHIREIKRI NE+ASRF+D PILNDRYL+L+LLGKGGFSEVHKGFDL    +VACK+H+LNP+WP+DKKD+YIKHALREI+IHK L+H RIV+V DVF+ID+DAFCTVLEY EGNDLDF+LKQNK IPER+AKS+ICQ+VSAL+YLN+RK P+IHYDLKPGNILL +    GEIKITDFGLSK+  D+ +NPE GM+LTSQGAGTYWYLPPECF T   PP ISSKVD+WSVGVIF+Q L+GKKPFG+NM+Q DILH NTIL AR I FPS  K+SDGAK+FIR+CCTYRK+LRPDVFQLCNDDYLKPKAQLKH++D + LPGP    + +PP S   S   S N
Sbjct:  551 ATVESLQRQLADQEHELMIQRDTVAKLQENALKSRDFIRELLIEKSVLERKTTRQKVMENRLRLGQFVTQRQGAHFEEKWVEGSRFKELDQRRKNIELVREEIERKKKQWNKRKPTLGDGKKNSKSKGD-EVSVDEFYEQLEIFDLRKQMLVKEDKEIQMELERLDRERNLHIREIKRIANEDASRFKDHPILNDRYLLLNLLGKGGFSEVHKGFDLVANRYVACKVHQLNPAWPKDKKDNYIKHALREINIHKTLNHPRIVKVFDVFDIDHDAFCTVLEYSEGNDLDFFLKQNKSIPEREAKSIICQVVSALKYLNERKPPVIHYDLKPGNILLGSGQVAGEIKITDFGLSKLMTDEEYNPETGMDLTSQGAGTYWYLPPECFETGREPPKISSKVDIWSVGVIFFQCLFGKKPFGHNMSQADILHENTILHARTIVFPSITKVSDGAKEFIRKCCTYRKDLRPDVFQLCNDDYLKPKAQLKHNLDTSSLPGP----VGIPPSSCHLSSYCSGN 1060
[Close]
BLAST of Protein kinase vs. Ensembl Cavefish
Match: tlk1b (tousled-like kinase 1b [Source:NCBI gene;Acc:326734])

HSP 1 Score: 511.146 bits (1315), Expect = 5.713e-163
Identity = 268/524 (51.15%), Postives = 363/524 (69.27%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS---------------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITS 3869
            +L +++E + K  E+ K+   K   +  K L+++S  E+++ RE+   ++L LG F   R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K+  KRKP S                KTK      G P L+P+        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI NE++S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  + A KIH+LN +W ++KK++Y KHA RE  IHK+LDH RIV+++D F++D D FCTVLE+CEGNDLDFYLKQ+K + E++A+S++ Q+ +ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD++  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S+ AK FIRRC  YRKE R DV QLC+D YL P  +  +          SSG+L   P S  SS I S
Sbjct:  182 DLRRQIEEQQKLLERYKERLNKCTTMSKKLLIEKSTQEKQSCREKSMQDRLRLGHFTPVRHGASFTEQWTDGYAFQNLIKQQEWVNQQREDIERQRKLLAKRKPPSTAPSQSPAPYGESKPRKTKAVNGSDGDPFLKPSLPTLLTVAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRISNEDSSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLFEQRYAAVKIHQLNKNWREEKKENYHKHACREYRIHKQLDHPRIVKLYDYFSLDTDTFCTVLEFCEGNDLDFYLKQHKLMSEKEARSIVMQIANALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDNYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVSNEAKAFIRRCLAYRKEDRYDVHQLCSDSYLLPHIRRSN----------SSGNLQATPSSPASSGIIS 695
[Close]
BLAST of Protein kinase vs. Ensembl Cavefish
Match: tlk2 (tousled like kinase 2 [Source:NCBI gene;Acc:103043685])

HSP 1 Score: 491.886 bits (1265), Expect = 1.145e-157
Identity = 258/481 (53.64%), Postives = 337/481 (70.06%), Query Frame = 3 
Query: 2382 EQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPN-----------------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            +Q +  RCKE         K   +  K L+++S+ E+ A R++   ++L LG F + R GA + E+WS+G  +Q+L K+++ +  QR++ E+++K+  K+KP S        Q   P LEPN                 E++ Q EI  +R  ++ KEE ++Q E ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++ +S+I Q+V+AL+YLN+ + PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD++  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYGKKPFG+N +Q DIL  NTIL+A  + FP  P +S  AK FIRRC  YRKE R DV QL +D +L P
Sbjct:   69 QQRMLERCKER------LNKCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWSDGYAFQNLIKQQERVNSQREDIERQRKLLAKKKPPS------ASQTPPPSLEPNKRKNKSNGAENEMLSLAEYHEQEEIFKLRLGHLKKEEAEIQVELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEGRSIIMQVVNALKYLNEIRPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDNYGVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGKKPFGHNQSQQDILQENTILKATEVQFPPKPGVSPEAKAFIRRCLVYRKEDRIDVHQLASDPFLLP 537
[Close]
BLAST of Protein kinase vs. Ensembl Cavefish
Match: tlk1a (tousled like kinase 1 [Source:NCBI gene;Acc:103028257])

HSP 1 Score: 498.434 bits (1282), Expect = 3.147e-157
Identity = 258/489 (52.76%), Postives = 351/489 (71.78%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS---------------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            +L ++++ + K  E+ K+   K   +  K L+++S  E++A RE+   ++L LGQF + R GA + E+W++G  +Q+L K+++ I +QR++ E+++K+  KRKP S                KTK     +  P L+P+        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE++S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN +W ++KK++Y KHA RE  IHK+LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD++  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P  S+ AK FIRRC  YRKE R DV QL +D YL P
Sbjct:  258 DLRRQIDEQQKLLEKYKERLNKCITMSKKLLIEKSTQEKQACREKSMQDRLRLGQFATVRHGASFTEQWTDGYAFQNLIKQQESINQQREDIERQRKLLAKRKPPSASNSQTPNANSEPKQRKTKAVNGAENDPFLKPSLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDSSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLIEQRYAAVKIHQLNKNWREEKKENYHKHACREYRIHKQLDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDNYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVASNEAKAFIRRCLAYRKEDRFDVHQLGSDSYLLP 746
[Close]
BLAST of Protein kinase vs. Ensembl Cavefish
Match: tlk1a (tousled like kinase 1 [Source:NCBI gene;Acc:103028257])

HSP 1 Score: 497.664 bits (1280), Expect = 3.414e-157
Identity = 258/489 (52.76%), Postives = 351/489 (71.78%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS---------------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            +L ++++ + K  E+ K+   K   +  K L+++S  E++A RE+   ++L LGQF + R GA + E+W++G  +Q+L K+++ I +QR++ E+++K+  KRKP S                KTK     +  P L+P+        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE++S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN +W ++KK++Y KHA RE  IHK+LDH RIV+++D F++D D FCTVLEYCEGNDLDFYLKQ+K + E++A+S++ Q+V+ALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD++  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P  S+ AK FIRRC  YRKE R DV QL +D YL P
Sbjct:  239 DLRRQIDEQQKLLEKYKERLNKCITMSKKLLIEKSTQEKQACREKSMQDRLRLGQFATVRHGASFTEQWTDGYAFQNLIKQQESINQQREDIERQRKLLAKRKPPSASNSQTPNANSEPKQRKTKAVNGAENDPFLKPSLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDSSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLIEQRYAAVKIHQLNKNWREEKKENYHKHACREYRIHKQLDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDNYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVASNEAKAFIRRCLAYRKEDRFDVHQLGSDSYLLP 727
[Close]
BLAST of Protein kinase vs. Ensembl Cavefish
Match: tlk2 (tousled like kinase 2 [Source:NCBI gene;Acc:103043685])

HSP 1 Score: 494.582 bits (1272), Expect = 7.540e-157
Identity = 258/481 (53.64%), Postives = 337/481 (70.06%), Query Frame = 3 
Query: 2382 EQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPN-----------------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            +Q +  RCKE         K   +  K L+++S+ E+ A R++   ++L LG F + R GA + E+WS+G  +Q+L K+++ +  QR++ E+++K+  K+KP S        Q   P LEPN                 E++ Q EI  +R  ++ KEE ++Q E ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++ +S+I Q+V+AL+YLN+ + PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD++  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYGKKPFG+N +Q DIL  NTIL+A  + FP  P +S  AK FIRRC  YRKE R DV QL +D +L P
Sbjct:  200 QQRMLERCKER------LNKCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWSDGYAFQNLIKQQERVNSQREDIERQRKLLAKKKPPS------ASQTPPPSLEPNKRKNKSNGAENEMLSLAEYHEQEEIFKLRLGHLKKEEAEIQVELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEGRSIIMQVVNALKYLNEIRPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDNYGVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGKKPFGHNQSQQDILQENTILKATEVQFPPKPGVSPEAKAFIRRCLVYRKEDRIDVHQLASDPFLLP 668
[Close]
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: TLK1 (tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841])

HSP 1 Score: 498.434 bits (1282), Expect = 1.334e-158
Identity = 265/503 (52.68%), Postives = 360/503 (71.57%), Query Frame = 3 
Query: 2331 QNNESSVINLK-GKLENL-------EQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP------------ASEKTKQTGKQKGSP-ELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNP-EGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            +NN+SS +  K GK+++L        +++E + K  E+ K+   K   +  K L+++SE E++A RE+   ++L LG F + R GA + E+W++G  +Q+L K+++WI +QR++ E+++K+  KRKP              +K ++T    G+   L   E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL++  +VA KIH+LN +W  +KK++Y KHA RE  IHK L+H RIV+++D F++D D+FCTVLEY EGNDLDFYLKQ+K + E++A+S+I Q+VSAL+YLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD++N  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYG+KPFG+N +Q DIL   TIL+A  + FP  P +S+ AK FIRRC  YRKE R DV QL  D YL P
Sbjct:  192 ENNQSSDLEKKEGKIDDLLRVNCDLRRQIEEQQKLVERYKERLNKCVVMSKKLLIEKSEQEKQACREKSMQDRLRLGHFVTVRHGATFTEQWTDGSAFQNLIKQQEWINQQREDIERQRKLLAKRKPPTAGHSASPMPAGEQKQRKTKAVNGAVNRLTVAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLQEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELNHPRIVKLYDYFSLDTDSFCTVLEYIEGNDLDFYLKQHKLMSEKEARSIIMQIVSALKYLNEIKPPIIHYDLKPGNILLVDGKSCGEIKITDFGLSKIMDDDNYNAVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQEKTILRATEVQFPVKPVVSNEAKAFIRRCLAYRKEDRIDVHQLAGDLYLMP 694
[Close]
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: TLK1 (tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841])

HSP 1 Score: 493.812 bits (1270), Expect = 1.974e-156
Identity = 267/519 (51.45%), Postives = 363/519 (69.94%), Query Frame = 3 
Query: 2331 QNNESSVINLK-GKLENL-------EQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP------------ASEKTKQTGKQKGSPE--LEPN---------------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNP-EGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            +NN+SS +  K GK+++L        +++E + K  E+ K+   K   +  K L+++SE E++A RE+   ++L LG F + R GA + E+W++G  +Q+L K+++WI +QR++ E+++K+  KRKP              +K ++T    G+ E  L+P                E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI NE+ S+F+D P LN+RYL+L LLG+GGFSEV+K FDL++  +VA KIH+LN +W  +KK++Y KHA RE  IHK L+H RIV+++D F++D D+FCTVLEY EGNDLDFYLKQ+K + E++A+S+I Q+VSAL+YLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD++N  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYG+KPFG+N +Q DIL   TIL+A  + FP  P +S+ AK FIRRC  YRKE R DV QL  D YL P
Sbjct:  213 ENNQSSDLEKKEGKIDDLLRVNCDLRRQIEEQQKLVERYKERLNKCVVMSKKLLIEKSEQEKQACREKSMQDRLRLGHFVTVRHGATFTEQWTDGSAFQNLIKQQEWINQQREDIERQRKLLAKRKPPTAGHSASPMPAGEQKQRKTKAVNGADEGFLKPATPQLSHVSLNRLTVAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLQEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELNHPRIVKLYDYFSLDTDSFCTVLEYIEGNDLDFYLKQHKLMSEKEARSIIMQIVSALKYLNEIKPPIIHYDLKPGNILLVDGKSCGEIKITDFGLSKIMDDDNYNAVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQEKTILRATEVQFPVKPVVSNEAKAFIRRCLAYRKEDRIDVHQLAGDLYLMP 731
[Close]
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: TLK1 (tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841])

HSP 1 Score: 489.574 bits (1259), Expect = 2.835e-155
Identity = 263/512 (51.37%), Postives = 359/512 (70.12%), Query Frame = 3 
Query: 2331 QNNESSVINLK-GKLENL-------EQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKP------------ASEKTKQTGKQKGS----------PELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNP-EGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            +NN+SS +  K G++++L        +++E + K  E+ K+   K   +  K L+++SE E++A RE+   ++L LG F + R GA + E+W++G  +Q+L K+++W+ +QR++ E+++K+  KRKP            A +K ++     G+          P L   E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL++  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEY  GNDLDFYLKQ+K + E++A+S+I Q+VSAL+YLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  D+++N  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYG+KPFG+N +Q DIL   TIL+A  + FP  P  S+ AK FIRRC  YRKE R  V QL +D YL P
Sbjct:  186 ENNQSSDLEKKEGRIDDLLRANCDLRRQIEEQQKLLEKFKERLNKCVTMSKKLLVEKSEQEKQACREKSMQDRLRLGHFVTVRHGATFTEQWTDGSAFQNLIKQQEWVNQQREDIERQRKLLAKRKPPMAAHMTSPASAAEQKQRKNKAVNGADDNFVKPSVPPTLTVAEYHEQEEILKLRLGHLKKEEAEIQAELERLERTRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLQEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYIHGNDLDFYLKQHKLMSEKEARSIIMQIVSALKYLNEIKPPIIHYDLKPGNILLVDGKSCGEIKITDFGLSKIMDDENYNAVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQEKTILRATEVQFPVKPVASNEAKAFIRRCLAYRKEDRIHVQQLASDLYLMP 697
[Close]
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: plk3 (polo-like kinase 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-6134])

HSP 1 Score: 113.62 bits (283), Expect = 7.100e-26
Identity = 82/271 (30.26%), Postives = 131/271 (48.34%), Query Frame = 3 
Query: 2946 LLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYL 3758
            LLGKGGF+  +   +    C  A KI     +  + +K  +     +EIS+H++L HR IV+    F  +N  +  +LE C G  L   L+  K + E + K  + QL+S LRYL+  +  ++H DLK GN  + ++ E+KI D GL+         PE  + T    GT  YL PE        P    + D+WS+G   +  L G+ PF    + +D+ +    +++   NFP  P +S  A+D +    T   +LR  +  L +  +L
Sbjct:   32 LLGKGGFARCYLVTEEYTGCHFAAKI----ITKQRVEKPGHRAKIEQEISLHRKLHHRHIVQFISSFKDENFIYI-ILELCNGQSLAHMLRSRKVLTETEVKYYLRQLISGLRYLH--QCGVVHRDLKLGNFFVTDSMEVKIGDLGLATTL----EPPEMRKRTV--CGTPNYLAPEVLNKRGHGP----EADIWSLGCAVFTMLAGRPPF----STSDLANTYACIRSGRFNFP--PSLSHAARDLLTSALTPDPDLRASLLDLQSHPFL 279
[Close]
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: stk32a (serine/threonine kinase 32A [Source:ZFIN;Acc:ZDB-GENE-091204-271])

HSP 1 Score: 95.9005 bits (237), Expect = 1.149e-22
Identity = 63/170 (37.06%), Postives = 90/170 (52.94%), Query Frame = 3 
Query: 3069 IKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTE-NGPPTISSKVDVWSVGVIFYQSLYGKKP 3575
            +++  RE+ I + L+H  +V +   F  + D F  V++   G DL ++L+Q+    E   +  +C+L  AL YL  R   IIH D+KP NILL  +G   ITDF ++ +        EG E  S  AGT  Y+ PE F +   G P  SS VD WS+GV  Y+ L G  P
Sbjct:   30 VRNVFRELQIMQELEHTFLVNLWYSFQDEEDMF-MVVDLLLGGDLRYHLQQSTRFQEEAVRLYLCELSLALDYLQQRH--IIHRDIKPDNILLDEHGHAHITDFNIATVV------KEG-EQASSMAGTKPYMAPEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWWP 189
[Close]
BLAST of Protein kinase vs. Ensembl Yeast
Match: CDC5 (Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603])

HSP 1 Score: 110.923 bits (276), Expect = 3.919e-25
Identity = 87/289 (30.10%), Postives = 138/289 (47.75%), Query Frame = 3 
Query: 2946 LLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTI---LQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVL 3803
             LG+GGF+   +  D     F A  + + +      K +   K  L EI IHK + H  IV+  D F  D++ +  +LE C    L   LK+ K + E + +    Q+  A++Y++ R+  +IH DLK GNI   +N  +KI DFGL+ +  ++       E      GT  Y+ PE  + ++     S +VD+WS+GV+ Y  L GK PF       D+   NTI   ++ R+ +FP    ISD  K  IR   +     RP + ++   DY+  +     S+   V+
Sbjct:   87 FLGEGGFARCFQIKDDSGEIFAAKTVAKASI-----KSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYI-LLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRR--VIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANES------ERKYTICGTPNYIAPEVLMGKHSGH--SFEVDIWSLGVMLYALLIGKPPF----QARDV---NTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIM--DYVWFRGTFPPSIPSTVM 350
[Close]
BLAST of Protein kinase vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631])

HSP 1 Score: 103.219 bits (256), Expect = 2.238e-22
Identity = 79/271 (29.15%), Postives = 129/271 (47.60%), Query Frame = 3 
Query: 2946 LLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALR-EISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDY 3755
            ++GKG F  V+   ++     +A K  E+     Q++       ALR E+S  K LDH  IV+ +  F   N+ +   LEY  G  +   ++      E   K L  Q++  L YL+ +   I+H D+K  N+LL  +G  KI+DFG+S+   D + N    ++T +  GT +++ PE   T+ G    S+KVD+WS+G I  +   GK+P+ N      +        A  I   + P IS   ++F+  C     E RP   +L +  +
Sbjct: 1180 MIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQ-YLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKG--ILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSN---SDMTMR--GTVFWMAPEMVDTKQG---YSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPF 1439
[Close]
BLAST of Protein kinase vs. Ensembl Yeast
Match: SNF1 (AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885])

HSP 1 Score: 100.908 bits (250), Expect = 5.268e-22
Identity = 85/277 (30.69%), Postives = 124/277 (44.77%), Query Frame = 3 
Query: 2931 YLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLK 3761
            Y I+  LG+G F +V   +       VA KI         D +        REIS  + L H  I++++DV     D    V+EY  GN+L  Y+ Q   + E++A+    Q++SA+ Y +  K  I+H DLKP N+LL  +  +KI DFGLS I  D +             G+  Y  PE     +G      +VDVWS GVI Y  L  + PF +      +L  N  +       P F  +S GA   I+R        R  + ++  DD+ K
Sbjct:   55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQG----RIEREISYLRLLRHPHIIKLYDVIK-SKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHK--IVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGN-------FLKTSCGSPNYAAPEVI---SGKLYAGPEVDVWSCGVILYVMLCRRLPFDDE--SIPVLFKN--ISNGVYTLPKF--LSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFK 307
[Close]
BLAST of Protein kinase vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649])

HSP 1 Score: 98.2117 bits (243), Expect = 6.858e-22
Identity = 87/265 (32.83%), Postives = 118/265 (44.53%), Query Frame = 3 
Query: 2931 YLILSLLGKGGFSEVHKGFDLEQLCFVACKI---HELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSF--PKISDGAKDFIRRCCTYR 3710
            + IL  LG G F  VH         F A K    H +        K   ++H   E  +   + H  I+R+   F  D+     V++Y EG +L   L++++  P   AK    ++  AL YL+ +   II+ DLKP NILL  NG IKITDFG +K  PD         +T    GT  Y+ PE   T+      +  VD WS GV+ Y+ L G  PF N+ T         IL A  + FP F  P   D  K  I R  + R
Sbjct:   88 FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTI-------VKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQ-DSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKD--IIYRDLKPENILLDKNGHIKITDFGFAKYVPD---------VTYTLCGTPDYIAPEVVSTK----PYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTY---ENILNAE-LKFPPFFHPDAQDLLKKLITRDLSER 325
[Close]
BLAST of Protein kinase vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124])

HSP 1 Score: 97.8265 bits (242), Expect = 7.516e-22
Identity = 81/259 (31.27%), Postives = 120/259 (46.33%), Query Frame = 3 
Query: 2937 ILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSF-PKISDGAKDFIRRCCTYR 3710
            I+  LG G F  VH    +    + A K+ +      Q  K   ++H   E  + K ++H  ++R+   F    + F  V++Y EG +L   L++++  P   AK    +++ AL YL+     II+ DLKP NILL  NG IKITDFG +K         E   +T    GT  Y+ PE   T+      +  VD WS+GV+ Y+ L G  PF +    T +     ILQ + +  P F P + D     I    T R
Sbjct:   72 IMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQ----QVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFM-VMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHN--IIYRDLKPENILLDRNGHIKITDFGFAK---------EVQTVTWTLCGTPDYIAPEVITTK----PYNKSVDWWSLGVLIYEMLAGYTPFYDT---TPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRR 307
[Close]
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO37283 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG68])

HSP 1 Score: 480.715 bits (1236), Expect = 1.865e-155
Identity = 257/454 (56.61%), Postives = 330/454 (72.69%), Query Frame = 3 
Query: 2478 SELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKG------------------SPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCN----NGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQ 3773
            + LE++  RE  + N+L LGQF   RQGA + + WSEG  +++L K+++ I ++R+E EK+KK+  K+KP+S     TGK+K                   SP L P E+Y + EI  +R   + KEE +LQ E ++LDRER+LHIREIKR+ +E+ SRF++ P LN++YL+LSLLGKGGFSEV+KG+DL    +VACKIH+L   W +DKK +YIKHALRE +IHK L+H RIV+++DVF ID ++FCTVLEYC+GNDLDF LKQ+K +PER+AK ++ Q V AL+YLN+ K P+IHYDLKPGNILL      +GE KITDFGLSKIF  D  +   MELTSQGAGTYWYLPPECFV    PP ISSKVDVWSVGVIFYQ LYG+KPFG++ TQ  IL N TIL+AR + FP+ P +S  AK+FIRRC  YRK+ R DV  LC+D YLKP ++
Sbjct:    2 ARLEKKRVRENCSENRLRLGQFVPVRQGAQFVDSWSEGYAFKELNKQQEKINQKREELEKQKKLLVKKKPSS---GATGKKKMRFIYKKGKSSDGEFTRPLSPVLSPMEYYEKEEILKLRAAALKKEETELQLELDKLDRERSLHIREIKRLQHEDNSRFKNHPKLNNQYLLLSLLGKGGFSEVYKGYDLVNHRYVACKIHQLIKEWKEDKKANYIKHALREYNIHKSLNHPRIVQLYDVFEIDVESFCTVLEYCDGNDLDFLLKQHKTVPEREAKCIVMQTVRALKYLNEIKPPVIHYDLKPGNILLVGTGAFSGETKITDFGLSKIFESDEDD--SMELTSQGAGTYWYLPPECFVVGKEPPKISSKVDVWSVGVIFYQMLYGRKPFGHDQTQASILENRTILKAREVEFPAKPVVSSEAKNFIRRCLAYRKDDRADVLTLCDDVYLKPTSK 450
[Close]
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO28073 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7H8])

HSP 1 Score: 159.073 bits (401), Expect = 3.017e-45
Identity = 79/124 (63.71%), Postives = 89/124 (71.77%), Query Frame = 3 
Query: 3333 GNILLCN----NGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKK----PFGNNMTQTDILHNNTILQARNINFPSFPKISDGAK 3680
            GNILL      +GE KITDFGLSKIF  D    + MELTSQGAGTYWYLPPECFV    PP ISSKVDVWSVGVIFYQ LYG++    PFG++ TQ  IL N TIL+AR + FP+ P +S  AK
Sbjct:    1 GNILLVGTGAFSGETKITDFGLSKIFESDED--DSMELTSQGAGTYWYLPPECFVVGKEPPKISSKVDVWSVGVIFYQMLYGRRYGQYPFGHDQTQASILENRTILKAREVEFPAKPVVSSEAK 122
[Close]
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO41399 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4I8])

HSP 1 Score: 113.235 bits (282), Expect = 5.858e-27
Identity = 81/268 (30.22%), Postives = 134/268 (50.00%), Query Frame = 3 
Query: 2913 PILNDRYLILSLLGKGGFSEVHKGF---DLEQLCFVACKIHELNPSWPQDKKDSYIKHA----LREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCN--NGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFI 3689
            P +N+ +++   LG+G ++ V+K F   D   +  + C            KK +  K A    L EI + + L+H  IV++ D F  D +    ++EYC G DL  ++   + +PER A+  + QL  AL+Y+  R   + H DLKP N+LL +  N  +KI DFG ++     H N E     S   G+  Y+ PE    +    +  + VD+WSVGVI Y++L+G+ PF    ++T +     +  +  I  P  P++S   +D +
Sbjct:   12 PKINN-FVVAEKLGQGSYATVYKAFKKGDNRDVVAIKCI-----------KKKTLSKAATENLLTEIELLRNLEHEHIVQLKD-FQWDENHIFLIMEYCGGGDLSRFIHSKRALPERMARKFLRQLACALQYM--RSYDVAHMDLKPQNLLLSSRHNPVLKIADFGFAQKL---HPNSEA----SNIRGSPLYMAPEMICCQ----SYDASVDLWSVGVILYETLFGEPPFK---SKTFVELEAKLRSSEPIKLPPGPRVSADCRDLL 250
[Close]
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO33022 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STC5])

HSP 1 Score: 112.464 bits (280), Expect = 6.552e-27
Identity = 94/265 (35.47%), Postives = 129/265 (48.68%), Query Frame = 3 
Query: 2925 DRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGE------IKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPS--FPKISDGAKDFIRR 3695
            D Y I   +GKG F +V K  +L+     A K  E++ S  ++ K    K A  E  I   LDH  IV + DVF         VLEY  G DL   +       E+DA + + Q++ ALRYL   +  IIH DLKP N+LL           IK+TDFG++K                +G G+  YL PE  + E     ++  VD+W+ GVI Y  L G  PF N  T+  +L   +ILQ+ N  FPS  +  +S+ AKD IR+
Sbjct:    5 DVYEITDFIGKGAFGQVSKCVNLQTREVFAVK--EIDFSGSEEDK----KKAQNEAKICGLLDHPSIVHLEDVFFTPRRMLL-VLEYLPGGDLFDGVVTRTQFSEKDACACVRQVLKALRYLT--RKGIIHRDLKPENLLLSERPSDHRPPIIKLTDFGIAKQL--------------KGNGSPLYLAPETILEEG----LTYAVDIWACGVILYLLLVGYPPFWNEQTEFLLL---SILQS-NYTFPSPYWDTVSEPAKDLIRK 238
[Close]
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO41242 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z6])

HSP 1 Score: 109.383 bits (272), Expect = 3.519e-26
Identity = 84/273 (30.77%), Postives = 140/273 (51.28%), Query Frame = 3 
Query: 2919 LNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILL---CNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGA-GTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQAR-NINFPSFPKISDGAKDFIRRCCTYRKELR 3722
            ++  Y +L L+G+G F++V +  + +     A K  EL  +  +DK+        +EI++ K L H  IV ++     + +  C ++EY  G  L   + Q     E+ A+ +  QL++AL YL+ R+  I+H D+KP N+LL    NN  IK+ DFGL++  P+D       ++ S GA G   +L PE  + E     I   VD+W+ GVIFY  L G  PF +N  +  +L   +IL+ +  +  P +  +S+ A+D + +      E R
Sbjct:    1 MSPNYDMLELIGEGSFAKVFRCIERKTGLEFAAK--ELRLTDVEDKEKIE-----QEIAVWKDLRHENIVSLYSSIR-EGETVCLIMEYVAGGSLFDEVIQQTYYSEKQARLVTRQLLNALEYLHSRR--IVHRDIKPDNLLLKRTGNNVTIKLADFGLAQALPND------TDVISCGASGAPMFLAPETVLEE----PIGRAVDIWACGVIFYLLLVGYPPFWSNSDEQLLL---SILRGQYTMPSPFWDNVSNDARDLVHKLIVVDPEAR 250
[Close]
BLAST of Protein kinase vs. Ensembl Medaka
Match: tlk1b (serine/threonine-protein kinase tousled-like 1-B [Source:NCBI gene;Acc:101169144])

HSP 1 Score: 502.286 bits (1292), Expect = 5.656e-159
Identity = 261/507 (51.48%), Postives = 354/507 (69.82%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS----------------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPS 3815
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ + RE+   ++L LG F + R GA Y E+W++G  +Q+L K+++ I +QR++ E+++K+  KRKP +                 K K        P L+P+        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE++S F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN +W ++KK++Y KHA RE  IHK+LDH RIV+++D F++D D FCTVLE+CEGNDLDFYLKQNK + E++A+S++ Q+VSALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD++  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP+ P+ S  AK FIRRC  YRKE R DV QLC+D YL P  +  +S      P PS
Sbjct:  236 DLRRQIDEQQKLLEKYKERLNKCITMSKKLLIEKSNQEKLSCREKSMQDRLRLGHFTTVRHGASYTEQWTDGYAFQNLIKQQESINQQREDIERQRKLLAKRKPPNPAAPSLSVASTSEPKQRKAKVVNGNDSDPFLKPSLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDSSAFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLFEQRYAAVKIHQLNKNWREEKKENYHKHACREYRIHKQLDHPRIVKLYDYFSLDTDTFCTVLEFCEGNDLDFYLKQNKLMSEKEARSIVMQIVSALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDNYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPAKPQASTEAKAFIRRCLAYRKEDRYDVHQLCSDSYLLPHMRRSNSSGSLQPPAPS 742
[Close]
BLAST of Protein kinase vs. Ensembl Medaka
Match: tlk1b (serine/threonine-protein kinase tousled-like 1-B [Source:NCBI gene;Acc:101169144])

HSP 1 Score: 502.671 bits (1293), Expect = 6.141e-159
Identity = 261/507 (51.48%), Postives = 354/507 (69.82%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS----------------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPS 3815
            +L ++++ + K  E+ K+   K   +  K L+++S  E+ + RE+   ++L LG F + R GA Y E+W++G  +Q+L K+++ I +QR++ E+++K+  KRKP +                 K K        P L+P+        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE++S F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN +W ++KK++Y KHA RE  IHK+LDH RIV+++D F++D D FCTVLE+CEGNDLDFYLKQNK + E++A+S++ Q+VSALRYLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD++  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP+ P+ S  AK FIRRC  YRKE R DV QLC+D YL P  +  +S      P PS
Sbjct:  249 DLRRQIDEQQKLLEKYKERLNKCITMSKKLLIEKSNQEKLSCREKSMQDRLRLGHFTTVRHGASYTEQWTDGYAFQNLIKQQESINQQREDIERQRKLLAKRKPPNPAAPSLSVASTSEPKQRKAKVVNGNDSDPFLKPSLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDSSAFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLFEQRYAAVKIHQLNKNWREEKKENYHKHACREYRIHKQLDHPRIVKLYDYFSLDTDTFCTVLEFCEGNDLDFYLKQNKLMSEKEARSIVMQIVSALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDNYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPAKPQASTEAKAFIRRCLAYRKEDRYDVHQLCSDSYLLPHMRRSNSSGSLQPPAPS 755
[Close]
BLAST of Protein kinase vs. Ensembl Medaka
Match: tlk1a (tousled like kinase 1 [Source:NCBI gene;Acc:101159625])

HSP 1 Score: 499.204 bits (1284), Expect = 3.174e-158
Identity = 259/514 (50.39%), Postives = 361/514 (70.23%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRK---------PAS------EKTKQTGKQKGSPELEPN--------EFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPP 3839
            +L ++++ + K  E+ K+   K   +  K L+++S  E++A RE+   ++L LG F + R GA + E+W++G  +Q + K+++WI +QR++ E+++K+  KRK         PA+       KTK     +  P L+P+        E++ Q EI  +R  ++ KEE ++QAE ERL+R RNLHIRE+KRI+NE++S+F+D P LN+RYL+L LLG+GGFSEV+K FDL +  + A KIH+LN +W ++KK++Y KHA RE  IHK LDH RIV+++D F++D D FCTV+E+CEGNDLDFYLKQ+K + E++A+S++ Q+V+AL+YLN+ K PIIHYDLKPGNILL +    GEIKITDFGLSKI  DD++  +GM+LTSQGAGTYWYLPPECFV    PP IS+KVDVWSVG+IF+Q LYG+KPFG+N +Q DIL  NTIL+A  + FP  P +S+ AK FIRRC  YRKE R DV QL +D YL P   ++ S     L   ++GS   PP
Sbjct:  199 DLRRQIDEQQKLLEKYKERLNKCITMSKKLLIEKSTQEKQACREKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQKIVKQQEWINQQREDIERQRKLLAKRKPPSSSSSQAPATNSESKQRKTKAVNGAESDPFLKPSLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDSSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLIEQRYAAVKIHQLNKNWREEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVMEFCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALKYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDNYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGIIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSNEAKAFIRRCLAYRKEDRSDVHQLGSDLYLLP--HIRRSSSSGNLQMSAAGSGLAPP 710
[Close]
BLAST of Protein kinase vs. Ensembl Medaka
Match: tlk2 (tousled like kinase 2 [Source:NCBI gene;Acc:101158767])

HSP 1 Score: 495.352 bits (1274), Expect = 1.846e-157
Identity = 266/526 (50.57%), Postives = 362/526 (68.82%), Query Frame = 3 
Query: 2265 EHNSENPKPATINSSDNAIIHNQNNESSVINLKG-KLENLEQELETRC-------KENEQLKDYRRKAREVLI---KTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS---------EKTKQTGKQKG--SPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNP-EGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            +H+  NP P  +     + + + N E S  ++K   L  L +  +  C       ++ + L+ Y+ +  + +    K L+++S+ E+ A R++   ++L LG F + R GA + E+W++G  +Q+L K+++ I  QR++ E+++K+  KRKP S         E+ K+  K  G  S  L   E++ Q EI  +R   + KEE ++QAE ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++ +S+I Q+V+AL+YLN+ + PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD +N  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYG+KPFG+N +Q DIL  NTIL+A ++ FP  P ++  AK FIRRC  YRKE R DV QL +D +L P
Sbjct:  115 QHSLSNP-PVAVQQGSPSSLGSINAELSSCSVKPISLHMLHKATQANCDLRRQIDEQQKMLERYKERLNKCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREDIERQRKLLAKRKPPSMAQTPPPSLEQNKRKSKTNGAESETLSQAEYHEQEEIFKLRLGYLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEGRSIIMQIVNALKYLNEIRPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNAVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATDVQFPPKPVVTPEAKAFIRRCLVYRKEDRIDVHQLASDPFLMP 639
[Close]
BLAST of Protein kinase vs. Ensembl Medaka
Match: tlk2 (tousled like kinase 2 [Source:NCBI gene;Acc:101158767])

HSP 1 Score: 494.582 bits (1272), Expect = 3.506e-157
Identity = 258/478 (53.97%), Postives = 345/478 (72.18%), Query Frame = 3 
Query: 2376 NLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPAS---------EKTKQTGKQKG--SPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNN---GEIKITDFGLSKIFPDDHHNP-EGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKP 3764
            +L ++++ + K  E+ K+   K   +  K L+++S+ E+ A R++   ++L LG F + R GA + E+W++G  +Q+L K+++ I  QR++ E+++K+  KRKP S         E+ K+  K  G  S  L   E++ Q EI  +R   + KEE ++QAE ERL+R RNLHIRE+KRI NE+ S+F+D P LNDRYL+L LLG+GGFSEV+K FDL +  +VA KIH+LN +W  +KK++Y KHA RE  IHK LDH RIV+++D F++D D+FCTVLEYCEGNDLDFYLKQ+K + E++ +S+I Q+V+AL+YLN+ + PIIHYDLKPGNILL N    GEIKITDFGLSKI  DD +N  +GMELTSQGAGTYWYLPPECFV    PP IS+KVDVWSVGVIFYQ LYG+KPFG+N +Q DIL  NTIL+A ++ FP  P ++  AK FIRRC  YRKE R DV QL +D +L P
Sbjct:  160 DLRRQIDEQQKMLERYKERLNKCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREDIERQRKLLAKRKPPSMAQTPPPSLEQNKRKSKTNGAESETLSQAEYHEQEEIFKLRLGYLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEGRSIIMQIVNALKYLNEIRPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNAVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATDVQFPPKPVVTPEAKAFIRRCLVYRKEDRIDVHQLASDPFLMP 637
[Close]
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000026488.1 (SMESG000026488.1)

HSP 1 Score: 1200.27 bits (3104), Expect = 0.000e+0
Identity = 567/567 (100.00%), Postives = 567/567 (100.00%), Query Frame = 3 
Query: 2181 KVFFNTSLSIKKDSSIDVAANRDVIPFTEHNSENPKPATINSSDNAIIHNQNNESSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITSSNHY 3881
            KVFFNTSLSIKKDSSIDVAANRDVIPFTEHNSENPKPATINSSDNAIIHNQNNESSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITSSNHY
Sbjct:  253 KVFFNTSLSIKKDSSIDVAANRDVIPFTEHNSENPKPATINSSDNAIIHNQNNESSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITSSNHY 819
[Close]
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000026488.1 (SMESG000026488.1)

HSP 1 Score: 1200.27 bits (3104), Expect = 0.000e+0
Identity = 567/567 (100.00%), Postives = 567/567 (100.00%), Query Frame = 3 
Query: 2181 KVFFNTSLSIKKDSSIDVAANRDVIPFTEHNSENPKPATINSSDNAIIHNQNNESSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITSSNHY 3881
            KVFFNTSLSIKKDSSIDVAANRDVIPFTEHNSENPKPATINSSDNAIIHNQNNESSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITSSNHY
Sbjct:  251 KVFFNTSLSIKKDSSIDVAANRDVIPFTEHNSENPKPATINSSDNAIIHNQNNESSVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHSTQSSQITSSNHY 817
[Close]
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000059835.1 (SMESG000059835.1)

HSP 1 Score: 820.846 bits (2119), Expect = 0.000e+0
Identity = 452/452 (100.00%), Postives = 452/452 (100.00%), Query Frame = 3 
Query:   96 MSENLIDELISESNYKTSYNTEYISSQSVQQDNDSTSSFLNLIEQEILTNNQMICDNYSPNFNMSECATNSNDQLAKPDVKSNGLDPSFEELLLTKLPQIIAIERSSIQFQVIDQNHPSLSKSFQNCFNSPXXXXXXXXXXPKQLVSFFQGYFAGIPRLTNELIDLTDKYWKSLISNNDDTAWENHXXXXXXXXXXXXXXXXXXXAGPVIRCRLRAXXXXXXXXXXXXXXVQPCSYMIQLPSNHFNSSSVDYNTMEVKANGMNNYLVSYINIVRECDTEYALKGSAAASLQKVITNSTFKQKQKVENVIDLPTSKQTSNRNFRRNMHTNQVAISNQLSVNISSPAYPNIEQSPLSGNAPLTYPLINNPRTDQYNKSNIFTNAQMQHQISQQRQLSMPMNHNQYMTRGASLSNVDPNQHRYSGPYETSHPSSLQYILENRNNVYPNVKQLANP 1451
            MSENLIDELISESNYKTSYNTEYISSQSVQQDNDSTSSFLNLIEQEILTNNQMICDNYSPNFNMSECATNSNDQLAKPDVKSNGLDPSFEELLLTKLPQIIAIERSSIQFQVIDQNHPSLSKSFQNCFNSPVLDLLVVVLDPKQLVSFFQGYFAGIPRLTNELIDLTDKYWKSLISNNDDTAWENHFKSVNEKNNFKNNFESEFEAGPVIRCRLRASSSSQFNQQYNYFFVQPCSYMIQLPSNHFNSSSVDYNTMEVKANGMNNYLVSYINIVRECDTEYALKGSAAASLQKVITNSTFKQKQKVENVIDLPTSKQTSNRNFRRNMHTNQVAISNQLSVNISSPAYPNIEQSPLSGNAPLTYPLINNPRTDQYNKSNIFTNAQMQHQISQQRQLSMPMNHNQYMTRGASLSNVDPNQHRYSGPYETSHPSSLQYILENRNNVYPNVKQLANP
Sbjct:    1 MSENLIDELISESNYKTSYNTEYISSQSVQQDNDSTSSFLNLIEQEILTNNQMICDNYSPNFNMSECATNSNDQLAKPDVKSNGLDPSFEELLLTKLPQIIAIERSSIQFQVIDQNHPSLSKSFQNCFNSPVLDLLVVVLDPKQLVSFFQGYFAGIPRLTNELIDLTDKYWKSLISNNDDTAWENHFKSVNEKNNFKNNFESEFEAGPVIRCRLRASSSSQFNQQYNYFFVQPCSYMIQLPSNHFNSSSVDYNTMEVKANGMNNYLVSYINIVRECDTEYALKGSAAASLQKVITNSTFKQKQKVENVIDLPTSKQTSNRNFRRNMHTNQVAISNQLSVNISSPAYPNIEQSPLSGNAPLTYPLINNPRTDQYNKSNIFTNAQMQHQISQQRQLSMPMNHNQYMTRGASLSNVDPNQHRYSGPYETSHPSSLQYILENRNNVYPNVKQLANP 452
[Close]
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000026492.1 (SMESG000026492.1)

HSP 1 Score: 582.022 bits (1499), Expect = 0.000e+0
Identity = 274/455 (60.22%), Postives = 356/455 (78.24%), Query Frame = 3 
Query: 2406 KENEQLKDYRRKAREVLIKTLMQQSELERRATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRDENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNINKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILSLLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREISIHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERDAKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKIFPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVIFYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRRCCTYRKELRPDVFQLCNDDYLKPKA 3770
            KEN +L D+++  +E LIK+L++ S+ ER   + +V+NN+L LG++ + R G HYE+K+  G K+ ++E KRK IE+Q+++NEK++K  NK KP  ++ K  GK + +PEL+P EF+ Q+E  +I KV +NKE+K+L  E E L R +N H+RE+KR++NEEASRF DFP LN+RY++LSLLGKGGFSEV+K FDL+Q  FVACK HELN +W  +KKDSYI+H LREI I K L+H RIV VHDVFN+D+D F  VLEYC+GNDLDFYLKQNKC+PERD K LI QLVSA++YL DR+ PIIH+DLKP NIL+  +G+IK+TDFGLSKIFPD     +G+ELTSQGAGTYWYLPPECFVT+ GP  I SKVDVWS+GV FYQ LYG+KPFG++ TQTDIL+NNTI  A+++ F   PK+SD AK+FI +C TY ++ RP +FQL   DYL+PK 
Sbjct:  152 KENRELSDHQKIEKENLIKSLIENSQREREVNKLKVHNNRLQLGEYVTVRHGVHYEQKFVPGSKFVEIEWKRKLIEKQKEDNEKKRKALNKCKPVGDRGK-LGKPRANPELDPYEFFIQSEKIEINKVRLNKEDKELDNELELLTRAKNSHLREMKRVENEEASRFNDFPTLNERYVVLSLLGKGGFSEVYKAFDLQQQRFVACKFHELNQNWTNEKKDSYIRHGLREIQIQKSLNHPRIVGVHDVFNVDSDTFVMVLEYCDGNDLDFYLKQNKCLPERDCKLLIAQLVSAVKYLTDRRTPIIHFDLKPSNILIV-DGDIKVTDFGLSKIFPDSDTTADGIELTSQGAGTYWYLPPECFVTDGGPQIIDSKVDVWSIGVNFYQCLYGRKPFGHDQTQTDILNNNTIRLAKSVAFLPNPKVSDAAKEFITQCLTYNRQDRPTIFQLHAHDYLRPKV 604
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BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000059833.1 (SMESG000059833.1)

HSP 1 Score: 286.96 bits (733), Expect = 5.653e-79
Identity = 146/146 (100.00%), Postives = 146/146 (100.00%), Query Frame = 3 
Query: 1710 MSVASNHSPANYYYSTAPNQILHNPLHINTSLTNQSQFVSSSVSPYCNPDRTQMTHQDYPSTPRNNPQPAIKQENYEMNICQNDWLSNSVLDSRNPSLMSNNSISIDIVEEILQAEEAKFENKSLEIEAVKSDSSDSLMGYLNDFM 2147
            MSVASNHSPANYYYSTAPNQILHNPLHINTSLTNQSQFVSSSVSPYCNPDRTQMTHQDYPSTPRNNPQPAIKQENYEMNICQNDWLSNSVLDSRNPSLMSNNSISIDIVEEILQAEEAKFENKSLEIEAVKSDSSDSLMGYLNDFM
Sbjct:    1 MSVASNHSPANYYYSTAPNQILHNPLHINTSLTNQSQFVSSSVSPYCNPDRTQMTHQDYPSTPRNNPQPAIKQENYEMNICQNDWLSNSVLDSRNPSLMSNNSISIDIVEEILQAEEAKFENKSLEIEAVKSDSSDSLMGYLNDFM 146
The following BLAST results are available for this feature:
BLAST of Protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TLK11.571e-15950.67tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC... [more]
TLK12.435e-15950.67tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC... [more]
TLK14.214e-15950.67tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC... [more]
TLK21.642e-15853.13tousled like kinase 2 [Source:HGNC Symbol;Acc:HGNC... [more]
TLK11.862e-15850.67tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of Protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tlk-17.638e-14445.64Serine/threonine-protein kinase tousled-like 1 [S... [more]
tlk-12.174e-14345.89Serine/threonine-protein kinase tousled-like 1 [S... [more]
tlk-12.262e-14345.64Serine/threonine-protein kinase tousled-like 1 [S... [more]
tlk-15.286e-14345.89Serine/threonine-protein kinase tousled-like 1 [S... [more]
par-12.328e-2434.02Serine/threonine-protein kinase par-1 [Source:Uni... [more]
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BLAST of Protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tlk5.530e-13764.72gene:FBgn0283657 transcript:FBtr0299579[more]
Tlk6.010e-13764.72gene:FBgn0283657 transcript:FBtr0333753[more]
Tlk6.010e-13764.72gene:FBgn0283657 transcript:FBtr0345319[more]
Tlk6.010e-13764.72gene:FBgn0283657 transcript:FBtr0299583[more]
Tlk6.388e-13764.72gene:FBgn0283657 transcript:FBtr0299580[more]
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BLAST of Protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tlk1a6.592e-16049.91tousled-like kinase 1a [Source:ZFIN;Acc:ZDB-GENE-0... [more]
tlk23.145e-15950.56tousled-like kinase 2 [Source:NCBI gene;Acc:407732... [more]
tlk1b4.137e-15950.67tousled-like kinase 1b [Source:NCBI gene;Acc:32673... [more]
tlk1b1.459e-15850.67tousled-like kinase 1b [Source:NCBI gene;Acc:32673... [more]
tlk22.276e-15850.56tousled-like kinase 2 [Source:NCBI gene;Acc:407732... [more]
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BLAST of Protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ccdc891.696e-16251.26coiled-coil domain containing 89 [Source:Xenbase;A... [more]
ccdc893.019e-16253.06coiled-coil domain containing 89 [Source:Xenbase;A... [more]
ccdc895.772e-16251.26coiled-coil domain containing 89 [Source:Xenbase;A... [more]
ccdc891.059e-15950.48coiled-coil domain containing 89 [Source:Xenbase;A... [more]
ccdc891.069e-15950.48coiled-coil domain containing 89 [Source:Xenbase;A... [more]
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BLAST of Protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tlk13.963e-16050.86tousled-like kinase 1 [Source:MGI Symbol;Acc:MGI:2... [more]
Tlk22.730e-15753.13tousled-like kinase 2 (Arabidopsis) [Source:MGI Sy... [more]
Tlk22.730e-15753.13tousled-like kinase 2 (Arabidopsis) [Source:MGI Sy... [more]
Tlk26.924e-15753.13tousled-like kinase 2 (Arabidopsis) [Source:MGI Sy... [more]
Tlk22.144e-13154.11tousled-like kinase 2 (Arabidopsis) [Source:MGI Sy... [more]
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BLAST of Protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8C0V0|TLK1_MOUSE2.772e-15950.86Serine/threonine-protein kinase tousled-like 1 OS=... [more]
sp|Q9UKI8|TLK1_HUMAN2.024e-15850.67Serine/threonine-protein kinase tousled-like 1 OS=... [more]
sp|Q1ECX4|TLK2_DANRE1.718e-15750.56Serine/threonine-protein kinase tousled-like 2 OS=... [more]
sp|Q90ZY6|TLK1B_DANRE2.278e-15750.48Serine/threonine-protein kinase tousled-like 1-B O... [more]
sp|O55047|TLK2_MOUSE1.909e-15653.13Serine/threonine-protein kinase tousled-like 2 OS=... [more]
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BLAST of Protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0REU00.000e+062.69Tousled kinase OS=Fasciola hepatica OX=6192 GN=D91... [more]
A0A4S2KC970.000e+064.47Protein kinase domain-containing protein OS=Opisth... [more]
H2KS660.000e+060.83Tousled-like kinase OS=Clonorchis sinensis OX=7992... [more]
A0A1S8X1E30.000e+064.47Kinase domain protein (Fragment) OS=Opisthorchis v... [more]
A0A5J4NI590.000e+064.47Tousled-like kinase OS=Paragonimus westermani OX=3... [more]
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BLAST of Protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tlk1b5.713e-16351.15tousled-like kinase 1b [Source:NCBI gene;Acc:32673... [more]
tlk21.145e-15753.64tousled like kinase 2 [Source:NCBI gene;Acc:103043... [more]
tlk1a3.147e-15752.76tousled like kinase 1 [Source:NCBI gene;Acc:103028... [more]
tlk1a3.414e-15752.76tousled like kinase 1 [Source:NCBI gene;Acc:103028... [more]
tlk27.540e-15753.64tousled like kinase 2 [Source:NCBI gene;Acc:103043... [more]
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BLAST of Protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TLK11.334e-15852.68tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC... [more]
TLK11.974e-15651.45tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC... [more]
TLK12.835e-15551.37tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC... [more]
plk37.100e-2630.26polo-like kinase 3 (Drosophila) [Source:ZFIN;Acc:Z... [more]
stk32a1.149e-2237.06serine/threonine kinase 32A [Source:ZFIN;Acc:ZDB-G... [more]
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BLAST of Protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
CDC53.919e-2530.10Polo-like kinase; controls targeting and activatio... [more]
BCK12.238e-2229.15MAPKKK acting in the protein kinase C signaling pa... [more]
SNF15.268e-2230.69AMP-activated S/T protein kinase; forms a complex ... [more]
TPK36.858e-2232.83cAMP-dependent protein kinase catalytic subunit; p... [more]
TPK27.516e-2231.27cAMP-dependent protein kinase catalytic subunit; p... [more]
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BLAST of Protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO372831.865e-15556.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO280733.017e-4563.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO413995.858e-2730.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO330226.552e-2735.47Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO412423.519e-2630.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tlk1b5.656e-15951.48serine/threonine-protein kinase tousled-like 1-B [... [more]
tlk1b6.141e-15951.48serine/threonine-protein kinase tousled-like 1-B [... [more]
tlk1a3.174e-15850.39tousled like kinase 1 [Source:NCBI gene;Acc:101159... [more]
tlk21.846e-15750.57tousled like kinase 2 [Source:NCBI gene;Acc:101158... [more]
tlk23.506e-15753.97tousled like kinase 2 [Source:NCBI gene;Acc:101158... [more]
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BLAST of Protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000026488.10.000e+0100.00SMESG000026488.1[more]
SMESG000026488.10.000e+0100.00SMESG000026488.1[more]
SMESG000059835.10.000e+0100.00SMESG000059835.1[more]
SMESG000026492.10.000e+060.22SMESG000026492.1[more]
SMESG000059833.15.653e-79100.00SMESG000059833.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30000664 ID=SMED30000664|Name=Protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=4789bp
TAGTTCTAATTTAATGGACTTATATTTATTTAGAAATCTTGTGACTGAAT
GAGTGTATATGTTTCTAAAATGAATTTGTTAATCATTTATTGAAAATGAG
TGAGAATTTAATAGATGAACTTATATCTGAGTCCAATTACAAAACATCTT
ATAACACAGAATACATCTCGTCTCAAAGTGTTCAACAAGATAACGATTCT
ACATCTTCATTTCTCAATTTAATAGAGCAAGAAATTTTAACTAATAATCA
AATGATATGCGACAACTATTCTCCGAATTTTAACATGTCTGAATGCGCAA
CCAATTCTAACGATCAATTGGCGAAGCCTGATGTAAAAAGTAATGGCTTG
GATCCAAGTTTTGAGGAGTTGTTACTAACCAAACTTCCACAAATAATTGC
CATAGAACGATCCAGCATTCAATTCCAAGTTATTGATCAAAATCACCCAA
GTCTTTCAAAATCGTTTCAAAATTGTTTCAATAGTCCAGTTTTGGATCTG
TTAGTGGTTGTCCTCGATCCGAAACAACTGGTTTCGTTTTTTCAAGGATA
TTTTGCCGGCATTCCAAGATTGACAAATGAATTGATAGATCTCACTGATA
AATACTGGAAATCATTAATCAGCAATAACGATGACACAGCTTGGGAAAAC
CATTTTAAATCAGTTAACGAAAAGAATAATTTTAAAAATAACTTTGAATC
TGAATTTGAAGCTGGTCCAGTTATTCGATGCAGGTTGCGGGCGTCTTCGA
GTTCGCAGTTCAATCAGCAGTATAATTACTTTTTTGTTCAGCCATGTAGT
TATATGATCCAACTCCCTTCAAACCATTTCAATTCTAGTTCTGTCGACTA
TAACACGATGGAAGTTAAAGCGAATGGCATGAACAATTATTTGGTTTCTT
ATATAAATATTGTCAGAGAGTGTGATACTGAATATGCTCTGAAGGGATCG
GCTGCTGCAAGTCTTCAAAAGGTTATTACGAATTCGACGTTTAAACAAAA
ACAGAAAGTGGAAAATGTTATTGACCTCCCAACAAGTAAACAAACCTCTA
ATCGAAATTTCCGACGAAATATGCACACTAATCAAGTGGCTATTAGTAAT
CAGTTATCTGTGAATATATCTTCTCCTGCATATCCTAATATTGAACAGTC
TCCTTTATCAGGAAACGCGCCATTAACTTATCCCTTGATAAACAATCCTA
GAACCGATCAATATAATAAATCTAATATTTTTACGAATGCTCAAATGCAA
CATCAAATTTCCCAACAGAGGCAATTATCTATGCCGATGAACCACAATCA
ATATATGACTCGAGGTGCATCTTTATCTAATGTTGATCCTAATCAGCATA
GGTATTCTGGACCATATGAAACATCACATCCCTCATCCTTGCAATATATA
CTGGAGAATCGGAACAATGTTTACCCAAATGTCAAACAACTTGCCAATCC
AACACATATGATGGGACAACACGGGCAAATGTATAAAAATCAACTTCAAC
CGAATCACACGTATTTTCTCCCAGCTGCTCAATCAGGCCAGCAAACTTGC
TCACTTAATTCACCTAATTCTTTCATGTCTTCACGCCATGTGATTCAAAT
GCCATCTAACAGTATTTTGATGTCGTCAGATCAATATTTTCGTAACGGTC
ATCAAATAAATATGATGGATCCAGTTCAAGTAGCCCAGCCGATGATGACT
GTTCAACCGATGTCAGTTGCCTCTAATCATTCACCGGCAAATTATTACTA
CAGCACTGCCCCAAATCAAATTCTCCATAATCCTCTTCATATAAATACAT
CCTTAACCAATCAATCGCAATTTGTCTCGTCGTCGGTTTCTCCATATTGT
AATCCTGATCGAACTCAAATGACGCACCAGGATTATCCCAGTACTCCGAG
AAACAACCCACAGCCGGCAATTAAGCAAGAGAATTATGAAATGAATATCT
GCCAAAATGACTGGCTTTCGAATTCAGTTCTTGACTCCAGAAATCCATCC
TTGATGTCAAATAATTCGATTTCCATTGATATTGTTGAAGAAATCCTTCA
GGCTGAAGAAGCCAAATTTGAAAATAAATCTCTAGAAATAGAAGCTGTAA
AGTCAGATAGCTCTGATTCACTGATGGGCTATCTGAATGATTTCATGTCA
ACTACCAACAATAACAACAACAACAACAACAAAGTGTTCTTCAATACGAG
CTTATCAATCAAAAAGGATTCATCAATTGATGTTGCAGCCAATCGCGACG
TTATTCCATTTACCGAGCACAACAGTGAGAACCCAAAACCGGCAACCATC
AATTCCAGTGATAATGCAATAATCCACAATCAGAACAATGAGTCCTCGGT
GATCAATTTGAAGGGCAAATTGGAAAATCTCGAGCAGGAGTTGGAAACCC
GGTGTAAGGAAAACGAACAGTTGAAAGATTACCGACGGAAAGCTCGAGAA
GTGTTAATCAAAACATTGATGCAGCAAAGTGAGCTGGAAAGGCGGGCTAC
TCGAGAGCGGGTCAATAACAATAAACTGCACCTGGGCCAGTTCAAATCGT
TCCGACAGGGAGCACATTACGAGGAGAAATGGTCGGAAGGCTTGAAATAT
CAAGATTTGGAAAAGAAACGGAAATGGATCGAAGAGCAGCGCGACGAGAA
CGAGAAGCGAAAGAAAATGTGGAACAAACGGAAACCTGCCAGCGAGAAAA
CCAAACAGACCGGCAAACAGAAAGGATCACCTGAACTGGAACCGAATGAA
TTCTATTGGCAGGCTGAAATCCACGACATCCGCAAGGTCAACATCAATAA
AGAGGAAAAAGATCTCCAGGCAGAAACTGAGAGACTCGATAGAGAGAGAA
ACCTTCACATTCGAGAAATAAAGCGGATCGATAACGAGGAAGCGTCAAGA
TTTCGAGATTTCCCAATATTGAACGATCGATATTTGATTTTGTCACTGCT
GGGCAAGGGCGGCTTTTCTGAGGTTCACAAAGGTTTCGATCTCGAACAGT
TGTGTTTTGTTGCGTGTAAAATTCACGAGTTGAATCCGAGTTGGCCCCAG
GACAAAAAGGACAGCTATATCAAGCACGCCTTGCGGGAAATATCGATCCA
CAAGCGACTCGATCACCGGAGGATCGTCCGGGTGCACGACGTTTTCAACA
TTGACAATGATGCCTTCTGCACGGTGCTCGAGTACTGCGAGGGCAATGAT
TTGGATTTCTACCTGAAACAGAACAAATGCATTCCAGAACGCGACGCCAA
GTCTCTCATATGTCAGCTAGTCAGTGCTCTCAGGTACCTGAACGACAGGA
AAAACCCGATCATTCATTACGATCTGAAACCCGGCAATATCCTGCTTTGC
AACAACGGTGAGATCAAAATCACCGATTTCGGACTCAGCAAGATATTCCC
CGATGACCATCACAACCCCGAGGGCATGGAATTGACCAGCCAAGGGGCAG
GCACATATTGGTATCTGCCGCCGGAATGCTTTGTCACCGAGAATGGGCCG
CCCACTATTTCCAGCAAGGTCGATGTCTGGTCGGTCGGGGTGATCTTCTA
TCAGTCACTCTATGGGAAAAAGCCGTTCGGTAACAATATGACACAAACTG
ACATCCTTCACAATAACACAATTCTCCAAGCCAGAAATATCAATTTCCCT
TCATTTCCTAAAATCAGCGATGGCGCCAAAGACTTTATCAGACGCTGCTG
CACTTATCGCAAAGAATTGCGGCCAGATGTCTTTCAGCTCTGCAACGATG
ATTATCTAAAGCCAAAGGCTCAGCTCAAACACAGCGTGGATGTGGCGGTG
TTGCCAGGTCCTTCATCTGGTTCTTTGACAGTGCCTCCTCACTCGACCCA
GTCATCTCAGATCACTAGTTCTAATCACTATTGATCGTCGCATGTGTCAC
CATTAATACCGCAAATTAATATTGCACTGTTATTATTGATTGGCGGTGGC
GGTATTAATGATTATCGATTGTCGTCGTGGCTCCACACAGAACTGTTCTC
TCTCTATCTATCTATCTATCTCTCGCTCTCACACACGCGCCCGTTTATAC
CGTTGCCATTGTTCACCTTCAGCAGCCCCGTGACGACATTTTTCATATTG
GTAAAAATACCGCCATCGCCACCGGTGTAGATTAATAATGTAATTGTGTT
ACAGCAATATTTGGTTGGCTGTCGCAATATCAGCTATTTCTCCCGTCGTT
TTCCAGATTTATTATTGCTATTGTGTTGAACTGTACATATTTTATATACA
TATTATACATATATATATTTTGTGATCAACTATTATCGTTTTCCGATTAT
GATGCCAGTTGGCTGGGGCAACGCCGCTTCCGCACGCGCTCGACAAGTTA
CGAATTAATGATTTAGAATGCATTTGTATTTGTACAGTTTTGTTGGTACC
TTGATATACATTGCTATATATATAGAGTTGAATCGATTTTATTTTTGGTT
TATCTATTGTAGATTGTGCAATAATCAATTTGTTCGTGCTTTTTGTCGCC
TGGGGATTATTGGACGTTTCAGGCAGTAGGAAATGTATCCGTTGATTAAT
TAGTTGTATCTAACATGTTAACGCGACCATAATGCTGTTCTTTTACTTGT
TTGTCTTTGACGTCCAATTTGTGGAAAAATTGTCTGTAATTACAAATTTC
TAACAAGGTTAGATGATATCGGTTCTGCCGTTTTTCTTTCCCATATATCC
AAAAAATCAACTAAAACTATAGAAAATTGCAGGGTGTGTTTAAATTGAAA
GTAAAATCATGAAATACAGTATATTCCAGATATTGAGTG
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protein sequence of SMED30000664-orf-1

>SMED30000664-orf-1 ID=SMED30000664-orf-1|Name=SMED30000664-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1263bp
MSENLIDELISESNYKTSYNTEYISSQSVQQDNDSTSSFLNLIEQEILTN
NQMICDNYSPNFNMSECATNSNDQLAKPDVKSNGLDPSFEELLLTKLPQI
IAIERSSIQFQVIDQNHPSLSKSFQNCFNSPVLDLLVVVLDPKQLVSFFQ
GYFAGIPRLTNELIDLTDKYWKSLISNNDDTAWENHFKSVNEKNNFKNNF
ESEFEAGPVIRCRLRASSSSQFNQQYNYFFVQPCSYMIQLPSNHFNSSSV
DYNTMEVKANGMNNYLVSYINIVRECDTEYALKGSAAASLQKVITNSTFK
QKQKVENVIDLPTSKQTSNRNFRRNMHTNQVAISNQLSVNISSPAYPNIE
QSPLSGNAPLTYPLINNPRTDQYNKSNIFTNAQMQHQISQQRQLSMPMNH
NQYMTRGASLSNVDPNQHRYSGPYETSHPSSLQYILENRNNVYPNVKQLA
NPTHMMGQHGQMYKNQLQPNHTYFLPAAQSGQQTCSLNSPNSFMSSRHVI
QMPSNSILMSSDQYFRNGHQINMMDPVQVAQPMMTVQPMSVASNHSPANY
YYSTAPNQILHNPLHINTSLTNQSQFVSSSVSPYCNPDRTQMTHQDYPST
PRNNPQPAIKQENYEMNICQNDWLSNSVLDSRNPSLMSNNSISIDIVEEI
LQAEEAKFENKSLEIEAVKSDSSDSLMGYLNDFMSTTNNNNNNNNKVFFN
TSLSIKKDSSIDVAANRDVIPFTEHNSENPKPATINSSDNAIIHNQNNES
SVINLKGKLENLEQELETRCKENEQLKDYRRKAREVLIKTLMQQSELERR
ATRERVNNNKLHLGQFKSFRQGAHYEEKWSEGLKYQDLEKKRKWIEEQRD
ENEKRKKMWNKRKPASEKTKQTGKQKGSPELEPNEFYWQAEIHDIRKVNI
NKEEKDLQAETERLDRERNLHIREIKRIDNEEASRFRDFPILNDRYLILS
LLGKGGFSEVHKGFDLEQLCFVACKIHELNPSWPQDKKDSYIKHALREIS
IHKRLDHRRIVRVHDVFNIDNDAFCTVLEYCEGNDLDFYLKQNKCIPERD
AKSLICQLVSALRYLNDRKNPIIHYDLKPGNILLCNNGEIKITDFGLSKI
FPDDHHNPEGMELTSQGAGTYWYLPPECFVTENGPPTISSKVDVWSVGVI
FYQSLYGKKPFGNNMTQTDILHNNTILQARNINFPSFPKISDGAKDFIRR
CCTYRKELRPDVFQLCNDDYLKPKAQLKHSVDVAVLPGPSSGSLTVPPHS
TQSSQITSSNHY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000101muscle cell
PLANA:0002089reproductive organ
PLANA:0002109X1 cell
PLANA:0002111X2 cell
PLANA:0003001lateral region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR008271Ser/Thr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR011009Kinase-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0016301kinase activity
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 197..217
NoneNo IPR availableCOILSCoilCoilcoord: 54..88
NoneNo IPR availableCOILSCoilCoilcoord: 144..164
NoneNo IPR availableCOILSCoilCoilcoord: 206..229
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 246..549
e-value: 2.2E-69
score: 236.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 551..571
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 158..190
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 158..184
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 552..571
NoneNo IPR availablePANTHERPTHR22974MIXED LINEAGE PROTEIN KINASEcoord: 44..534
NoneNo IPR availablePANTHERPTHR22974:SF23TOUSLED-LIKE KINASE, ISOFORM Gcoord: 44..534
NoneNo IPR availableCDDcd13990STKc_TLKcoord: 254..529
e-value: 0.0
score: 516.872
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 255..530
e-value: 8.0E-74
score: 261.2
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 258..530
e-value: 5.9E-60
score: 202.9
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 255..530
score: 40.668
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 261..284
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 381..393
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 242..540