UPF0193 protein EVG1

Overview
NameUPF0193 protein EVG1
Smed IDSMED30000605
Length (bp)887
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of UPF0193 protein EVG1 (SMED30000605) t-SNE clustered cells

Violin plots show distribution of expression levels for UPF0193 protein EVG1 (SMED30000605) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of UPF0193 protein EVG1 (SMED30000605) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for UPF0193 protein EVG1 (SMED30000605) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30000605

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30000605h1SMcG0001006 SmedASXL_071778SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30000605h1SMcG0001006 SmedASXL_012882SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30000605h1SMcG0001006 dd_Smed_v4_9772_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30000605h1SMcG0001006 dd_Smed_v4_9772_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30000605h1SMcG0001006 dd_Smed_v4_9772_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30000605h1SMcG0001006 dd_Smed_v4_9772_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30000605h1SMcG0001006 dd_Smed_v6_9772_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
reproductive organSMED30000605h1SMcG0001006 Contig28824uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30000605h1SMcG0001006 Contig28824newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
epidermisSMED30000605h1SMcG0001006 dd_Smed_v4_9772_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Human
Match: C22orf23 (chromosome 22 open reading frame 23 [Source:HGNC Symbol;Acc:HGNC:18589])

HSP 1 Score: 88.9669 bits (219), Expect = 1.882e-20
Identity = 67/211 (31.75%), Postives = 108/211 (51.18%), Query Frame = 1 
Query:  163 NFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXX--------------XXXMNNTKHINPRNY--SGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSS 747
             ++  T  LL++MM ESKLTN+QQR+I   +  GD+LPL+ +    +                 +    H+ P N   + G  S++            ++P    T++ + EK RL ++ A G D+  +K K     + A        ++DRF+EL+ EI++R+ FL  M+ LG+ K YR  I  EIS+ + EME ID +R+ EL K L++
Sbjct:   24 TYTPGTCELLRVMMKESKLTNIQQRHIMDIMKRGDALPLQCSPTSSQRVLPSKQIASPIYLPPILAARPHLRPANMCQANGAYSREQ-----------FKPQ--ATRDLEKEKQRLQNIFATGKDMEERKRKAPPARQKA-----PAPELDRFEELVKEIQERKEFLADMEALGQGKQYRGIILAEISQKLREMEDIDHRRSEELRKGLAT 216
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Human
Match: C22orf23 (chromosome 22 open reading frame 23 [Source:HGNC Symbol;Acc:HGNC:18589])

HSP 1 Score: 88.9669 bits (219), Expect = 1.882e-20
Identity = 67/211 (31.75%), Postives = 108/211 (51.18%), Query Frame = 1 
Query:  163 NFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXX--------------XXXMNNTKHINPRNY--SGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSS 747
             ++  T  LL++MM ESKLTN+QQR+I   +  GD+LPL+ +    +                 +    H+ P N   + G  S++            ++P    T++ + EK RL ++ A G D+  +K K     + A        ++DRF+EL+ EI++R+ FL  M+ LG+ K YR  I  EIS+ + EME ID +R+ EL K L++
Sbjct:   24 TYTPGTCELLRVMMKESKLTNIQQRHIMDIMKRGDALPLQCSPTSSQRVLPSKQIASPIYLPPILAARPHLRPANMCQANGAYSREQ-----------FKPQ--ATRDLEKEKQRLQNIFATGKDMEERKRKAPPARQKA-----PAPELDRFEELVKEIQERKEFLADMEALGQGKQYRGIILAEISQKLREMEDIDHRRSEELRKGLAT 216
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Human
Match: C22orf23 (chromosome 22 open reading frame 23 [Source:HGNC Symbol;Acc:HGNC:18589])

HSP 1 Score: 88.9669 bits (219), Expect = 1.882e-20
Identity = 67/211 (31.75%), Postives = 108/211 (51.18%), Query Frame = 1 
Query:  163 NFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXX--------------XXXMNNTKHINPRNY--SGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSS 747
             ++  T  LL++MM ESKLTN+QQR+I   +  GD+LPL+ +    +                 +    H+ P N   + G  S++            ++P    T++ + EK RL ++ A G D+  +K K     + A        ++DRF+EL+ EI++R+ FL  M+ LG+ K YR  I  EIS+ + EME ID +R+ EL K L++
Sbjct:   24 TYTPGTCELLRVMMKESKLTNIQQRHIMDIMKRGDALPLQCSPTSSQRVLPSKQIASPIYLPPILAARPHLRPANMCQANGAYSREQ-----------FKPQ--ATRDLEKEKQRLQNIFATGKDMEERKRKAPPARQKA-----PAPELDRFEELVKEIQERKEFLADMEALGQGKQYRGIILAEISQKLREMEDIDHRRSEELRKGLAT 216
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Human
Match: C22orf23 (chromosome 22 open reading frame 23 [Source:HGNC Symbol;Acc:HGNC:18589])

HSP 1 Score: 69.707 bits (169), Expect = 1.208e-13
Identity = 41/106 (38.68%), Postives = 64/106 (60.38%), Query Frame = 1 
Query:  430 TKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSS 747
            T++ + EK RL ++ A G D+  +K K     + A        ++DRF+EL+ EI++R+ FL  M+ LG+ K YR  I  EIS+ + EME ID +R+ EL K L++
Sbjct:   95 TRDLEKEKQRLQNIFATGKDMEERKRKAPPARQKA-----PAPELDRFEELVKEIQERKEFLADMEALGQGKQYRGIILAEISQKLREMEDIDHRRSEELRKGLAT 195
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Fly
Match: CG5280 (gene:FBgn0035952 transcript:FBtr0076552)

HSP 1 Score: 55.0694 bits (131), Expect = 1.373e-8
Identity = 49/198 (24.75%), Postives = 101/198 (51.01%), Query Frame = 1 
Query:  124 PCQGSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMN-NTKHINPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKK 714
            P  G+G ++S    +S ET +L+++++ ESK++ L ++ I  ++ NG+ LPL +       +  +  T  I  R  +   ++   I+   + + S+YRP      + +  K +L   MA GT L     K     +    + + +T+ D  +EL+++I +R  +L  M+ +G+ K YR  I  +I++ +  ++ ++ K
Sbjct:   45 PPGGAGAFHSAKVQYSKETADLIRLLVKESKMSMLVRKQIDESLRNGEPLPLPEPPRPNTNNDPDKETLAILDRARNAKRKNLRQIEASGAYKQSYYRPPADNRMHGEKAKSQLQFTMA-GTHLPDPAIKP----RRRPREEQLVTEEDLINELLDQINERAEWLTEMESMGQGKKYRPEIRDQIAERLRRIQALESK 237
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Zebrafish
Match: si:dkey-43k4.3 (si:dkey-43k4.3 [Source:ZFIN;Acc:ZDB-GENE-120215-146])

HSP 1 Score: 85.8853 bits (211), Expect = 1.409e-19
Identity = 69/201 (34.33%), Postives = 110/201 (54.73%), Query Frame = 1 
Query:  133 GSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNTKHINPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDR--LASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSEL 729
            GS    S    +  +T+ L+K+MM ES+LT+ QQR I+  + NG +LP+   S   + +  + T+ +       G + K + ++  +   ++ R   + +  R LEK++  L +L++ G   +G  T       +  E P     +DRF E+++EIEDRR FL+ M  LGK   Y+Q I TEIS+ I E+E IDKKR+ EL
Sbjct:    5 GSKYKESGIPQYRTDTRQLIKLMMQESRLTDFQQRQINNKLKNGGALPITFYSSPLEPNTPSETR-VTRVGTLVGQQQKRSAERCRAG-DNYKREQFLPSAARDLEKEKRKLQNLLSTGQKDAGP-THSQRESTERREQP-----VDRFQEVLDEIEDRRQFLEEMMSLGKGHQYQQLINTEISQKICELEEIDKKRSEEL 197
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Xenopus
Match: C22orf23 (chromosome 4 C22orf23 homolog [Source:NCBI gene;Acc:100485066])

HSP 1 Score: 119.783 bits (299), Expect = 5.976e-32
Identity = 75/210 (35.71%), Postives = 121/210 (57.62%), Query Frame = 1 
Query:  133 GSGLWN-SYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNTKHINPRNYSGGVRSKDTIDKLESTQTS------FYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKIL 741
            G+G WN + PA +S ETQ L+++MM ESKLTN Q+R I   +  GD+LP++                I+ R  +     +  +   E  +         ++P   +  N+  EK RL ++MA G DL    T+++   ++ +E+ +     DRFDEL+ E+++R +FL+ M+ LGK KDYR  I TEIS+ + EMEI+DK+R++EL+++L
Sbjct:   27 GTGFWNNAKPAQYSKETQELIRVMMEESKLTNFQKRQIKERLQGGDALPVQCHPSSTDSGSKRAAAAISQRPKATLQPCRPRLRPAEKCRAGDAYCRDKFQPRPTRDLNK--EKCRLQNIMATGKDLPA-PTRVIPQKENWEEEGEK----DRFDELVAEVQERWDFLEEMEALGKGKDYRNIINTEISQKLREMEILDKQRSTELKELL 229
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Mouse
Match: 1700088E04Rik (RIKEN cDNA 1700088E04 gene [Source:MGI Symbol;Acc:MGI:1920774])

HSP 1 Score: 91.2781 bits (225), Expect = 1.674e-21
Identity = 76/216 (35.19%), Postives = 110/216 (50.93%), Query Frame = 1 
Query:  160 ANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNTKHINPRNYSGGVRSKDT-----IDKLESTQTSFYRPSQVKTKN-------------RQLEKD--RLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSS 747
            A ++  T  LL++MM ESKLTN QQR+I  T+  G  LPL                  NP +   G  SK       +  + +T  S  RP+ +   N             R LEK+  RL ++ A G D   +K K+  + +   EDP    ++DRFDEL+ EI+DR+ FL  M+ LG+ + YR  I  EIS+ + EME ID++R+ EL K L++
Sbjct:   23 AGYTPGTCELLRVMMKESKLTNFQQRHIMDTMKRGAPLPL----------------QCNPTSSLRGSPSKKAASAIYLPPILATH-SHLRPASLCQANGAYSREQFKPQATRDLEKEKRRLQNIFATGKDKEERK-KVPHVRQ---EDP--APELDRFDELVKEIQDRKEFLAAMEALGQGRQYRSIILAEISQKLREMEDIDRRRSKELRKALAT 215
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Mouse
Match: 1700088E04Rik (RIKEN cDNA 1700088E04 gene [Source:MGI Symbol;Acc:MGI:1920774])

HSP 1 Score: 91.2781 bits (225), Expect = 1.674e-21
Identity = 76/216 (35.19%), Postives = 110/216 (50.93%), Query Frame = 1 
Query:  160 ANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNTKHINPRNYSGGVRSKDT-----IDKLESTQTSFYRPSQVKTKN-------------RQLEKD--RLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSS 747
            A ++  T  LL++MM ESKLTN QQR+I  T+  G  LPL                  NP +   G  SK       +  + +T  S  RP+ +   N             R LEK+  RL ++ A G D   +K K+  + +   EDP    ++DRFDEL+ EI+DR+ FL  M+ LG+ + YR  I  EIS+ + EME ID++R+ EL K L++
Sbjct:   23 AGYTPGTCELLRVMMKESKLTNFQQRHIMDTMKRGAPLPL----------------QCNPTSSLRGSPSKKAASAIYLPPILATH-SHLRPASLCQANGAYSREQFKPQATRDLEKEKRRLQNIFATGKDKEERK-KVPHVRQ---EDP--APELDRFDELVKEIQDRKEFLAAMEALGQGRQYRSIILAEISQKLREMEDIDRRRSKELRKALAT 215
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Mouse
Match: 1700088E04Rik (RIKEN cDNA 1700088E04 gene [Source:MGI Symbol;Acc:MGI:1920774])

HSP 1 Score: 72.4034 bits (176), Expect = 3.504e-15
Identity = 50/122 (40.98%), Postives = 75/122 (61.48%), Query Frame = 1 
Query:  388 ESTQTSFYRPSQVKTKNRQLEKD--RLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSS 747
            ES  T+F +   + T  R LEK+  RL ++ A G D   +K K+  + +   EDP    ++DRFDEL+ EI+DR+ FL  M+ LG+ + YR  I  EIS+ + EME ID++R+ EL K L++
Sbjct:   39 ESKLTNFQQRHIMDTMKRDLEKEKRRLQNIFATGKDKEERK-KVPHVRQ---EDP--APELDRFDELVKEIQDRKEFLAAMEALGQGRQYRSIILAEISQKLREMEDIDRRRSKELRKALAT 154
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Mouse
Match: 1700088E04Rik (RIKEN cDNA 1700088E04 gene [Source:MGI Symbol;Acc:MGI:1920774])

HSP 1 Score: 72.4034 bits (176), Expect = 3.504e-15
Identity = 50/122 (40.98%), Postives = 75/122 (61.48%), Query Frame = 1 
Query:  388 ESTQTSFYRPSQVKTKNRQLEKD--RLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSS 747
            ES  T+F +   + T  R LEK+  RL ++ A G D   +K K+  + +   EDP    ++DRFDEL+ EI+DR+ FL  M+ LG+ + YR  I  EIS+ + EME ID++R+ EL K L++
Sbjct:   39 ESKLTNFQQRHIMDTMKRDLEKEKRRLQNIFATGKDKEERK-KVPHVRQ---EDP--APELDRFDELVKEIQDRKEFLAAMEALGQGRQYRSIILAEISQKLREMEDIDRRRSKELRKALAT 154
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Mouse
Match: 1700088E04Rik (RIKEN cDNA 1700088E04 gene [Source:MGI Symbol;Acc:MGI:1920774])

HSP 1 Score: 72.0182 bits (175), Expect = 1.131e-14
Identity = 44/106 (41.51%), Postives = 68/106 (64.15%), Query Frame = 1 
Query:  430 TKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSS 747
            T++ + EK RL ++ A G D   +K K+  + +   EDP    ++DRFDEL+ EI+DR+ FL  M+ LG+ + YR  I  EIS+ + EME ID++R+ EL K L++
Sbjct:   95 TRDLEKEKRRLQNIFATGKDKEERK-KVPHVRQ---EDP--APELDRFDELVKEIQDRKEFLAAMEALGQGRQYRSIILAEISQKLREMEDIDRRRSKELRKALAT 194
[Close]
BLAST of UPF0193 protein EVG1 vs. UniProt/SwissProt
Match: sp|Q9D9S1|EVG1_MOUSE (UPF0193 protein EVG1 homolog OS=Mus musculus OX=10090 PE=2 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 1.171e-20
Identity = 76/216 (35.19%), Postives = 110/216 (50.93%), Query Frame = 1 
Query:  160 ANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNTKHINPRNYSGGVRSKDT-----IDKLESTQTSFYRPSQVKTKN-------------RQLEKD--RLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSS 747
            A ++  T  LL++MM ESKLTN QQR+I  T+  G  LPL                  NP +   G  SK       +  + +T  S  RP+ +   N             R LEK+  RL ++ A G D   +K K+  + +   EDP    ++DRFDEL+ EI+DR+ FL  M+ LG+ + YR  I  EIS+ + EME ID++R+ EL K L++
Sbjct:   23 AGYTPGTCELLRVMMKESKLTNFQQRHIMDTMKRGAPLPL----------------QCNPTSSLRGSPSKKAASAIYLPPILATH-SHLRPASLCQANGAYSREQFKPQATRDLEKEKRRLQNIFATGKDKEERK-KVPHVRQ---EDP--APELDRFDELVKEIQDRKEFLAAMEALGQGRQYRSIILAEISQKLREMEDIDRRRSKELRKALAT 215
[Close]
BLAST of UPF0193 protein EVG1 vs. UniProt/SwissProt
Match: sp|Q9BZE7|EVG1_HUMAN (UPF0193 protein EVG1 OS=Homo sapiens OX=9606 GN=C22orf23 PE=1 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 9.038e-20
Identity = 67/211 (31.75%), Postives = 108/211 (51.18%), Query Frame = 1 
Query:  163 NFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXX--------------XXXMNNTKHINPRNY--SGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSS 747
             ++  T  LL++MM ESKLTN+QQR+I   +  GD+LPL+ +    +                 +    H+ P N   + G  S++            ++P    T++ + EK RL ++ A G D+  +K K     + A        ++DRF+EL+ EI++R+ FL  M+ LG+ K YR  I  EIS+ + EME ID +R+ EL K L++
Sbjct:   24 TYTPGTCELLRVMMKESKLTNIQQRHIMDIMKRGDALPLQCSPTSSQRVLPSKQIASPIYLPPILAARPHLRPANMCQANGAYSREQ-----------FKPQ--ATRDLEKEKQRLQNIFATGKDMEERKRKAPPARQKA-----PAPELDRFEELVKEIQERKEFLADMEALGQGKQYRGIILAEISQKLREMEDIDHRRSEELRKGLAT 216
[Close]
BLAST of UPF0193 protein EVG1 vs. UniProt/SwissProt
Match: sp|Q9VSS7|EVG1_DROME (UPF0193 protein EVG1 homolog OS=Drosophila melanogaster OX=7227 GN=CG5280 PE=3 SV=1)

HSP 1 Score: 55.0694 bits (131), Expect = 1.377e-7
Identity = 49/198 (24.75%), Postives = 101/198 (51.01%), Query Frame = 1 
Query:  124 PCQGSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMN-NTKHINPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKK 714
            P  G+G ++S    +S ET +L+++++ ESK++ L ++ I  ++ NG+ LPL +       +  +  T  I  R  +   ++   I+   + + S+YRP      + +  K +L   MA GT L     K     +    + + +T+ D  +EL+++I +R  +L  M+ +G+ K YR  I  +I++ +  ++ ++ K
Sbjct:   45 PPGGAGAFHSAKVQYSKETADLIRLLVKESKMSMLVRKQIDESLRNGEPLPLPEPPRPNTNNDPDKETLAILDRARNAKRKNLRQIEASGAYKQSYYRPPADNRMHGEKAKSQLQFTMA-GTHLPDPAIKP----RRRPREEQLVTEEDLINELLDQINERAEWLTEMESMGQGKKYRPEIRDQIAERLRRIQALESK 237
[Close]
BLAST of UPF0193 protein EVG1 vs. TrEMBL
Match: V4B1A0 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_230313 PE=4 SV=1)

HSP 1 Score: 156.377 bits (394), Expect = 4.273e-43
Identity = 96/221 (43.44%), Postives = 141/221 (63.80%), Query Frame = 1 
Query:  112 MDSRP-CQGSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXM-----NNTKHINPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKN---RQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSS 747
            M ++P     G WNS  A +S +TQ LLK MMNESKLTN QQR++ +++ +G SLP +       + ++       +K +NP+NY+GGVRSKDT++ L     +F +P     KN      EK+RLA++MAFG D+   + + V +  + +E      +IDRFDEL  E+E+R+ FL  M KLGK +DY+ +IETEIS+L+ EME+IDKKRT +L+ +L +
Sbjct:    1 MAAKPNTMNGGFWNSPQAQYSPQTQKLLKEMMNESKLTNFQQRHLEKSLRSGSSLPSECNPTSSARPRVVKQTKKPSKILNPKNYTGGVRSKDTMEAL----GAFEKPEYSLPKNNARSAREKERLANMMAFGKDVDNIQKQKVQVPVEIEEP----VEIDRFDELQLEVEERQKFLADMTKLGKGRDYK-HIETEISQLVREMEVIDKKRTKQLDSLLKT 212
[Close]
BLAST of UPF0193 protein EVG1 vs. TrEMBL
Match: A0A267DG60 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig012093g1 PE=4 SV=1)

HSP 1 Score: 157.147 bits (396), Expect = 1.201e-42
Identity = 95/243 (39.09%), Postives = 133/243 (54.73%), Query Frame = 1 
Query:   79 LTKFNLQNLG*MD-SRPCQGSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNT--------KHINPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDAD----------EDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSSQ 750
            L ++N Q +  MD + P Q  GLWNS P  +S +TQ LLK MM ESKLTNLQ R +S T+  G SLP         + + N+         K +NP+NY   +R+++ I    + +   YRP+    +N+  EK RLA+ MAFG +      +    G              E P     +DRFDEL  E+EDRR FLD+M+  G+   YR  I+ EIS+L+ EMEIIDKKR  ELE+++ ++
Sbjct:   24 LVEYNYQLINGMDRNMPVQSGGLWNSTPVQYSAQTQQLLKDMMQESKLTNLQMRKVSETMKKGSSLPTDLPPTSSARQRSNSAGKPRGPMPKVLNPKNYQSSLRTREQIVATGAYEKPAYRPTGPSGRNQDAEKRRLANRMAFGDECPPDDGRGDVGGSGGRRKGGVRRMTLEAPAPEPTLDRFDELAEEVEDRRRFLDQMEAAGQGAKYRAKIQAEISQLVREMEIIDKKRNEELERMMRAE 266
[Close]
BLAST of UPF0193 protein EVG1 vs. TrEMBL
Match: A0A1I8GL79 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 2.349e-42
Identity = 91/230 (39.57%), Postives = 125/230 (54.35%), Query Frame = 1 
Query:  124 PCQGSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNT--------KHINPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDAD----------EDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSSQ*FG 759
            P Q  GLWNS P  +S +TQ LLK MM ESKLTNLQ R +S T+  G SLP         + + N+         K +NP+NY   +R+++ I    + +   YRP+    +N+  EK RLA+ MAFG +      +    G              E P     +DRFDEL  E+EDRR FLD+M+  G+   YR  I+ EIS+L+ EMEIIDKKR  ELE+++ ++  G
Sbjct:    6 PVQSGGLWNSTPVQYSAQTQQLLKDMMQESKLTNLQMRKVSETMKKGSSLPTDLPPTSSARQRSNSAGKPRGPMPKVLNPKNYQSSLRTREQIVATGAYEKPAYRPTGPSGRNQDAEKRRLANRMAFGDECPPDDGRGDVGGSGGRRKGGVRRMTLEAPAPEPTLDRFDELAEEVEDRRRFLDQMEAAGQGAKYRAKIQAEISQLVREMEIIDKKRNEELERMMRAERSG 235
[Close]
BLAST of UPF0193 protein EVG1 vs. TrEMBL
Match: A0A1S3I5D2 (UPF0193 protein EVG1 OS=Lingula unguis OX=7574 GN=LOC106160827 PE=4 SV=1)

HSP 1 Score: 147.132 bits (370), Expect = 2.225e-39
Identity = 85/215 (39.53%), Postives = 128/215 (59.53%), Query Frame = 1 
Query:  121 RPCQGSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNTKH-----INPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSSQ 750
            +P    G WNS P ++S ETQ LLK MM ESKLTN QQR +S  + +G++LP+        K +    K      +NPR+  GG+R K+TI+   + +   Y+P+ +K    + +K+RLA++MA+G D+     + +    D   +P+    IDRF EL +EIE+R+ FLD M  +G+   YR  I TEIS+ I EME+ID+K+T +L+ +L  Q
Sbjct:    7 QPVAQGGFWNSQPTSYSQETQQLLKQMMKESKLTNFQQRELSNKVRSGETLPVTCNPTSSAKPRQPKAKPPPQKVVNPRSAGGGIRLKETIESTGAYERPDYQPAHIKPVTEK-DKERLANIMAYGEDVQPPSVENIVRRMDPSPEPE----IDRFQELQDEIEERKRFLDDMDAIGQGHKYRAIISTEISQKIREMELIDQKKTKQLKGLLQLQ 216
[Close]
BLAST of UPF0193 protein EVG1 vs. TrEMBL
Match: R7U6R9 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_165907 PE=4 SV=1)

HSP 1 Score: 141.739 bits (356), Expect = 2.819e-37
Identity = 84/211 (39.81%), Postives = 131/211 (62.09%), Query Frame = 1 
Query:  142 LWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMN-----NTKHINPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKD--RLASLMAFGTDLSGKKTKIV-SLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSSQ 750
            +WN+  A +S +TQ LLK MM ESKL N Q+R +++ +S+G +LP         K +++      +K INPR +S  +R+K+ I+   + +   + P  +       E+D  RLA++MA+G DL  K  K   ++GK     PK   K+DRFDEL  E+E+RR+FL+ M  LGK  +Y+  IETEIS+LI +ME+IDKKR+ EL ++++++
Sbjct:    1 MWNTPKAGYSAQTQKLLKDMMQESKLNNFQKRQLNKVVSDGSNLPSSCHPTSSAKPRLHPQPRPQSKVINPREHSVQIRTKEEIESTGAYEREQFIPMPMSRYRGFYEEDKIRLANMMAYGEDLPPKNVKKARAMGK-----PKPQPKVDRFDELEKEVEERRSFLEEMVSLGKGHEYKAIIETEISRLIRDMELIDKKRSDELARLIAAE 206
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Cavefish
Match: si:dkey-43k4.3 (chromosome 13 C22orf23 homolog [Source:NCBI gene;Acc:103030575])

HSP 1 Score: 92.4337 bits (228), Expect = 4.822e-22
Identity = 66/202 (32.67%), Postives = 105/202 (51.98%), Query Frame = 1 
Query:  142 LWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNTKHINPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKD--RLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKIL 741
            LWN     +SN+T+ LL++MM ES+LT+ QQR ++  +  G +LPL+              +    +  +  VR +    +  S   ++ R     +  R LEK+  RL ++ A G +            K A+E     T  DRF E+++EIE+RR FL+ M  LG+ +DY   I  EIS+ I E+E+ID KR+ EL+ ++
Sbjct:   15 LWNCPRVKYSNDTRELLQLMMRESRLTSFQQRQLNNQLKKGGALPLRCNPTSSAPPLQAQPQPSLSKGRALSVRPQRRSAEQCSAGDNYTRERFQPSAARDLEKEKRRLQNIFATGQEEPQLSVPQTQPPKRAEE-----THTDRFQEVLDEIEERRQFLEEMTALGRGRDYNHIINFEISQKIKELELIDMKRSEELKTLM 211
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Cavefish
Match: si:dkey-43k4.3 (chromosome 13 C22orf23 homolog [Source:NCBI gene;Acc:103030575])

HSP 1 Score: 92.4337 bits (228), Expect = 8.053e-22
Identity = 66/202 (32.67%), Postives = 105/202 (51.98%), Query Frame = 1 
Query:  142 LWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNTKHINPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKD--RLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKIL 741
            LWN     +SN+T+ LL++MM ES+LT+ QQR ++  +  G +LPL+              +    +  +  VR +    +  S   ++ R     +  R LEK+  RL ++ A G +            K A+E     T  DRF E+++EIE+RR FL+ M  LG+ +DY   I  EIS+ I E+E+ID KR+ EL+ ++
Sbjct:   15 LWNCPRVKYSNDTRELLQLMMRESRLTSFQQRQLNNQLKKGGALPLRCNPTSSAPPLQAQPQPSLSKGRALSVRPQRRSAEQCSAGDNYTRERFQPSAARDLEKEKRRLQNIFATGQEEPQLSVPQTQPPKRAEE-----THTDRFQEVLDEIEERRQFLEEMTALGRGRDYNHIINFEISQKIKELELIDMKRSEELKTLM 211
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Cavefish
Match: si:dkey-43k4.3 (chromosome 13 C22orf23 homolog [Source:NCBI gene;Acc:103030575])

HSP 1 Score: 67.0106 bits (162), Expect = 2.596e-13
Identity = 52/142 (36.62%), Postives = 74/142 (52.11%), Query Frame = 1 
Query:  337 PR-NYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKD------RLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKIL 741
            PR  YS   R    +   ES  TSF    Q +  N QL++D      RL ++ A G +            K A+E     T  DRF E+++EIE+RR FL+ M  LG+ +DY   I  EIS+ I E+E+ID KR+ EL+ ++
Sbjct:   19 PRVKYSNDTRELLQLMMRESRLTSF----QQRQLNNQLKRDLEKEKRRLQNIFATGQEEPQLSVPQTQPPKRAEE-----THTDRFQEVLDEIEERRQFLEEMTALGRGRDYNHIINFEISQKIKELELIDMKRSEELKTLM 151
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Sea Lamprey
Match: si:dkey-43k4.3 (si:dkey-43k4.3 [Source:ZFIN;Acc:ZDB-GENE-120215-146])

HSP 1 Score: 105.145 bits (261), Expect = 1.934e-27
Identity = 78/210 (37.14%), Postives = 109/210 (51.90%), Query Frame = 1 
Query:  112 MDSRPCQGSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNTKHINPRNYSGG---VRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFG-TDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSEL 729
            M  R  +G GLW    A FS  T++LL++MM E++LTNLQQR+++  I+NG+SLPL   +    +              S G   +R        ++ +   YRP     KN + EK RL +LMA G  D  G   +                ++DRF EL+ EIE+RR FL  M+ LG+ K Y   I ++IS+ I EME ID+KRT EL
Sbjct:    9 MAGRGTEG-GLWAPAGAAFSPATRDLLRVMMKEARLTNLQQRHLTAKIANGESLPLSSHAPTSARRYRKPPPQARSTAASRGRPHLRPASDCMAGDAYKREQYRPK--PGKNTEAEKQRLQNLMATGRADEEGGTHRPRQPRTPP----PPEPELDRFTELMEEIEERRVFLQEMEALGRSKQYAPLIHSQISQKIREMEDIDRKRTKEL 211
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Nematostella
Match: EDO36841 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHG6])

HSP 1 Score: 139.043 bits (349), Expect = 4.597e-40
Identity = 88/221 (39.82%), Postives = 131/221 (59.28%), Query Frame = 1 
Query:  121 RPCQGSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNN---------TKHINPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSI--TKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSSQ 750
            +P    G+W++ PA  S ETQ LLK+MM ESKLTN Q+R +S  ++ G SLP+       ++ +             K +N R+ SGG RSK+ I+ L  T    YRP+  K  + + EK +L ++MA+G    GK+   + + K A    KS+   ++DRFDE++ EIE+R+ FL+ M+ LG+ K YR  I TEIS+ I E+E+IDKKR+ EL+  +  Q
Sbjct:    6 QPVAKGGIWSTQPAPMSKETQQLLKVMMEESKLTNFQRRQLSDKMTKGQSLPVSVNPTTSQQGQRPRQTSAAKKPLPKVMNARHLSGGKRSKEVIEVLHDTGEEPYRPAPTKYISTE-EKRKLQNVMAYGEH--GKE---IGMKKPAKPASKSMEEVEVDRFDEVLQEIEERKQFLEEMESLGQGKKYRTVINTEISQKIRELELIDKKRSQELDVAIKEQ 220
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Medaka
Match: ENSORLT00000027040.1 (chromosome 1 C22orf23 homolog [Source:NCBI gene;Acc:101166449])

HSP 1 Score: 68.5514 bits (166), Expect = 1.389e-13
Identity = 59/203 (29.06%), Postives = 107/203 (52.71%), Query Frame = 1 
Query:  112 MDSRPCQGSGLWN-SYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNTKHINPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDAD-EDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKK 714
            M++ P    GLWN   P   S ++Q+ +++M  ES+LT+L   N SR    G ++P K +      +       +  R +    R+ ++     S +   +RP    T++ + EK RL +++A     + K+    S  K  + E+P +    +RF+E+++EIEDRR FL  M+ LG+E++Y   I  EIS+ + E++++ +K
Sbjct:    1 MEAFPRSSGGLWNNPRPTGSSKDSQDWMRMMREESRLTSLLN-NHSRCSKKGLAVPQKASFPLADPA-------VKRRTFRPQRRTAESCQSGNSYEREKFRPG--PTRDMEAEKRRLQNILA-----AEKEPTAASPPKTPEAENPGAPE--ERFEEVLHEIEDRRQFLADMEALGQEREYISIINAEISQKLQELKMLQEK 186
[Close]
BLAST of UPF0193 protein EVG1 vs. Ensembl Medaka
Match: ENSORLT00000032774.1 (chromosome 1 C22orf23 homolog [Source:NCBI gene;Acc:101166449])

HSP 1 Score: 45.8246 bits (107), Expect = 4.973e-6
Identity = 37/113 (32.74%), Postives = 61/113 (53.98%), Query Frame = 1 
Query:  391 STQTSFYRPSQVKT----KNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDAD-EDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKK 714
            + +T F  P Q+      ++ + EK RL +++A     + K+    S  K  + E+P +       +EL++EIEDRR FL  M+ LG+E++Y   I  EIS+     ++IDKK
Sbjct:    7 AVETDFQLPPQMDWIEVQRDMEAEKRRLQNILA-----AEKEPTAASPPKTPEAENPGAP------EELLHEIEDRRQFLADMEALGQEREYISIINAEISQ-----QLIDKK 103
[Close]
BLAST of UPF0193 protein EVG1 vs. Planmine SMEST
Match: SMESG000056865.1 (SMESG000056865.1)

HSP 1 Score: 392.889 bits (1008), Expect = 1.088e-139
Identity = 210/213 (98.59%), Postives = 212/213 (99.53%), Query Frame = 1 
Query:  112 MDSRPCQGSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDXXXXXXXXXXXXXXXMNNTKHINPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSSQ 750
            MDSRPCQGSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDSLPLKKASEKPKKSKMNNTKH+NPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVS+GKD DEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSSQ
Sbjct:    1 MDSRPCQGSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISNGDSLPLKKASEKPKKSKMNNTKHLNPRNYSGGVRSKDTIDKLESTQTSFYRPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSVGKDEDEDPKSITKIDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDKKRTSELEKILSSQ 213
The following BLAST results are available for this feature:
BLAST of UPF0193 protein EVG1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
C22orf231.882e-2031.75chromosome 22 open reading frame 23 [Source:HGNC S... [more]
C22orf231.882e-2031.75chromosome 22 open reading frame 23 [Source:HGNC S... [more]
C22orf231.882e-2031.75chromosome 22 open reading frame 23 [Source:HGNC S... [more]
C22orf231.208e-1338.68chromosome 22 open reading frame 23 [Source:HGNC S... [more]
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BLAST of UPF0193 protein EVG1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of UPF0193 protein EVG1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG52801.373e-824.75gene:FBgn0035952 transcript:FBtr0076552[more]
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BLAST of UPF0193 protein EVG1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
si:dkey-43k4.31.409e-1934.33si:dkey-43k4.3 [Source:ZFIN;Acc:ZDB-GENE-120215-14... [more]
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BLAST of UPF0193 protein EVG1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
C22orf235.976e-3235.71chromosome 4 C22orf23 homolog [Source:NCBI gene;Ac... [more]
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BLAST of UPF0193 protein EVG1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
1700088E04Rik1.674e-2135.19RIKEN cDNA 1700088E04 gene [Source:MGI Symbol;Acc:... [more]
1700088E04Rik1.674e-2135.19RIKEN cDNA 1700088E04 gene [Source:MGI Symbol;Acc:... [more]
1700088E04Rik3.504e-1540.98RIKEN cDNA 1700088E04 gene [Source:MGI Symbol;Acc:... [more]
1700088E04Rik3.504e-1540.98RIKEN cDNA 1700088E04 gene [Source:MGI Symbol;Acc:... [more]
1700088E04Rik1.131e-1441.51RIKEN cDNA 1700088E04 gene [Source:MGI Symbol;Acc:... [more]
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BLAST of UPF0193 protein EVG1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|Q9D9S1|EVG1_MOUSE1.171e-2035.19UPF0193 protein EVG1 homolog OS=Mus musculus OX=10... [more]
sp|Q9BZE7|EVG1_HUMAN9.038e-2031.75UPF0193 protein EVG1 OS=Homo sapiens OX=9606 GN=C2... [more]
sp|Q9VSS7|EVG1_DROME1.377e-724.75UPF0193 protein EVG1 homolog OS=Drosophila melanog... [more]
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BLAST of UPF0193 protein EVG1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
V4B1A04.273e-4343.44Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
A0A267DG601.201e-4239.09Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1I8GL792.349e-4239.57Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1S3I5D22.225e-3939.53UPF0193 protein EVG1 OS=Lingula unguis OX=7574 GN=... [more]
R7U6R92.819e-3739.81Uncharacterized protein OS=Capitella teleta OX=283... [more]
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BLAST of UPF0193 protein EVG1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
si:dkey-43k4.34.822e-2232.67chromosome 13 C22orf23 homolog [Source:NCBI gene;A... [more]
si:dkey-43k4.38.053e-2232.67chromosome 13 C22orf23 homolog [Source:NCBI gene;A... [more]
si:dkey-43k4.32.596e-1336.62chromosome 13 C22orf23 homolog [Source:NCBI gene;A... [more]
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BLAST of UPF0193 protein EVG1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
si:dkey-43k4.31.934e-2737.14si:dkey-43k4.3 [Source:ZFIN;Acc:ZDB-GENE-120215-14... [more]
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BLAST of UPF0193 protein EVG1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of UPF0193 protein EVG1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO368414.597e-4039.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of UPF0193 protein EVG1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSORLT00000027040.11.389e-1329.06chromosome 1 C22orf23 homolog [Source:NCBI gene;Ac... [more]
ENSORLT00000032774.14.973e-632.74chromosome 1 C22orf23 homolog [Source:NCBI gene;Ac... [more]
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BLAST of UPF0193 protein EVG1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000056865.11.088e-13998.59SMESG000056865.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30000605 ID=SMED30000605|Name=UPF0193 protein EVG1|organism=Schmidtea mediterranea sexual|type=transcript|length=887bp
GTTAACTAATAAGCTGCATAGTTACTGAAAATTTGTAATTAAAAATTAAT
TAATACAAATAAATTTATAATATTGTCTTTGACGAAATTTAACTTACAAA
ATCTTGGTTAAATGGATAGTCGTCCATGCCAGGGTAGTGGACTGTGGAAT
TCATACCCAGCGAATTTCAGTAATGAAACTCAGAATTTGTTGAAAATAAT
GATGAATGAATCAAAATTAACAAACCTACAACAAAGAAATATTTCTAGAA
CTATTTCAAATGGTGATTCTTTACCCCTTAAGAAGGCGTCGGAGAAGCCT
AAGAAAAGTAAAATGAACAACACAAAGCATATAAATCCGAGAAATTATTC
AGGTGGGGTTCGAAGTAAAGATACGATCGATAAATTAGAATCCACACAAA
CATCATTTTACCGTCCTAGTCAAGTTAAAACAAAGAACCGGCAGTTGGAA
AAAGATCGATTAGCCAGTTTAATGGCATTTGGAACTGATTTAAGTGGGAA
AAAAACAAAAATTGTTTCGCTGGGAAAAGACGCAGATGAAGATCCTAAAT
CAATAACAAAAATTGATAGATTTGATGAATTAATCAATGAAATTGAAGAT
CGGAGAAACTTTTTAGATAGAATGAAAAAGCTTGGAAAAGAAAAAGATTA
TCGGCAAAATATAGAAACAGAAATATCTAAGCTCATCTTGGAAATGGAAA
TAATTGATAAGAAGCGAACAAGTGAATTGGAAAAAATCTTAAGTTCTCAG
TGATTTGGTAATTGATCATAATGTATTGGTTTTAAGTATCACTAATTACT
GATAATTTGTCAGTAGTGTTGAAAGTTGTGTAAAAATAAATTTTGTGTTA
ATACGTTACTTATATGAAGAAAAATACTTTGCTGTCG
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protein sequence of SMED30000605-orf-1

>SMED30000605-orf-1 ID=SMED30000605-orf-1|Name=SMED30000605-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=214bp
MDSRPCQGSGLWNSYPANFSNETQNLLKIMMNESKLTNLQQRNISRTISN
GDSLPLKKASEKPKKSKMNNTKHINPRNYSGGVRSKDTIDKLESTQTSFY
RPSQVKTKNRQLEKDRLASLMAFGTDLSGKKTKIVSLGKDADEDPKSITK
IDRFDELINEIEDRRNFLDRMKKLGKEKDYRQNIETEISKLILEMEIIDK
KRTSELEKILSSQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR007914UPF0193
Vocabulary: molecular function
TermDefinition
GO:0003674molecular_function
Vocabulary: cellular component
TermDefinition
GO:0005575cellular_component
Vocabulary: biological process
TermDefinition
GO:0008150biological_process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 181..201
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 44..74
IPR007914Uncharacterised protein family UPF0193PFAMPF05250UPF0193coord: 7..208
e-value: 1.4E-54
score: 185.1
IPR007914Uncharacterised protein family UPF0193PANTHERPTHR28348FAMILY NOT NAMEDcoord: 7..211