cilia- and flagella-associated protein 61
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30000512 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Human
Match: CFAP61 (cilia and flagella associated protein 61 [Source:HGNC Symbol;Acc:HGNC:15872]) HSP 1 Score: 885.56 bits (2287), Expect = 0.000e+0 Identity = 497/1238 (40.15%), Postives = 736/1238 (59.45%), Query Frame = 3
Query: 54 MYARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPL-ANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIF-INTDKGKIPENFGTQFTQIKSIT--DYKNWF---ILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPSNDSQTSSTEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNASIRSG----------LNDIPNNFE-------------------------FPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLN--EHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEG-YFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
++ RRTES D I+ LI + +FGK N+I ++EKA L+VTL + EI+ A+F DYPN + DW + + + + PLN+LFMH F++ E EI+ TV+ +H+IF I + T F Q+ +I Y+ F I R ++ P L++R A+ ED DDLMPIF TILK+ YGE++LAE+++AQ+++ +V EV G AVGF+SV + +N+ LL+ F L F G P E+ + L+ + S D++ S+ +V E S + A + +++SG L+DI + + G S A IQLF I+E YE RS+DF+ VF LF ++++ +I++P L PEF L++NFV++ P L +LY FH+ L+ + IR A D ++ ++ + L+++IL DL++++ AR+ G L A+VAE +IVG+ V++ E DIEYIRSHYNIEDFIYF+HH R EHGH+ HFA+NPIFR +K FLKE +R K+ +YY VY K N HSL + L LVP+RPRRQI+Y ++KL NAP++ + + Y L H NRKL +EPK+T+N +I+VVGAS+ G+SFLE+L F H+KFNNL L+S +GLP D + + D F+ K L +L V+VV G MT IDR K + ++ ++PYDH+I+ TG QY +PCPTEA I T +E N RRY+ VP N +N+ FK L ++R+N + E II+YG++ ++Y + T+L++G+ G RIH V+PP + +N+ VE AV L AGV ++ + +AQ+ND P+ I S SFTT P RL+C +F S+ +K V+Y F+A+ND+CLV+D+RLVIDT FHTND++IRAAG +TKF RYY+ +W+H+ F+S+ +G +L+ L LFDPTL PV PP LIP+Y + ++ ILPG +HYL +++P++ PL QPNYG L TG + G YFR+H+N+YK VETITCL ++ +P NY++L+G HE+ LNNL +R++ENLI DL+ +F + W +A +HDRF DL++E++++L ++ S E+ + E + T + R+ L F S K+ V++ + ++ YN YHLPMYA P +V
Sbjct: 14 VHCRRTESQDVYCIKSLIRKFTCKLFGKLNIIYLLEKANLAVTLCNDKEEIMAQATFLDYPN-WNVAKQDDWVSVFRELDSDIPCTPLNTLFMHLFVAVDEYSVGCCKEILRTVYKAVPELHFIFLIVPSYMSLGSTLITVFDQVGNIPCLTYEEDFAVHICHRHSHYPQLHVRKARVEDHDDLMPIFMRYDTILKETYGEYFLAELIEAQDEENHAVVCEVEGTAVGFMSVCSRVNMQLLHECFDLGPFHGLCFPHPDDVLESPQDLSVRRSQDAELRSSSQGSQKIVEELQEPVSPDTMENIQGNIAREAASE-EALTAVQSGNVSEPEDIEKLSDISTGYAQYHHVSSRSLASLVLPEEPVHFRPIYRGASAAFCIQLFCIDEKYEARSLDFMNFVFSLFSDKNFCVISLPHLTPEFFLIQNFVKMVPFNTCTLEQDLYVFHRAGLLKSINIRFATLLDTPGVENLVSTLMLNKSILEDLDRYNKARKDPDGTLLQAFVAEVAEQIVGIAVIRNEMDIEYIRSHYNIEDFIYFSHHQREEHGHMHHFALNPIFRHYTKFFLKEILRLGFKSCLYYRVYPKSREGKFQNPYAHSLTSALHYLVPVRPRRQIVYPLEKLGINAPSKAVSKDPMSYALNHTNRKLTLEPKITVNAKIIVVGASSVGISFLETLVFCSHMKFNNLTLISTHGLPGKKLLDTEQRKFLASDHCFNDKDYALMSLCSWVNVVVGRMTGIDRAAKHVVLSTDEIVPYDHLILCTGQQYQVPCPTEADISQHLTNREVPNSSQRRYT---------GKVPCNHFTLNEEEDCFKALIWIRNNSITTEGNIIVYGNTIDTYTTVETLLNLGVSGSRIHLVQPPPASTITCINNYSVESAVADALGAAGVTMYRDAILAQWNDGLH-PDPIYSASFTTPTKPFRLQCSMFFSFCEKNVDYETFKALNDACLVYDSRLVIDTNFHTNDIAIRAAGSLTKFSNRYYSNEWTHSNFSSKEIGFQLAAAMLHLFDPTLEPVTEPPANLDRLIPMYKGAKIQGGILPGSYHYLHIAKPAIPTPLEVQMAQPNYGLELVTGS--AKNGTYFRIHINKYKMVETITCLSREPFPASNYIRLFGQHEQLLNNLCARYDENLITDLYSYFTEPWCLALFHDRFIDLRKELRQILASKEEEDLPSIEQLAHQIEDEEINPTEKPRQYLKRVFEESIYKTLVERSTLDYLHYNRYHLPMYAWPGIV 1237
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Human
Match: CFAP61 (cilia and flagella associated protein 61 [Source:HGNC Symbol;Acc:HGNC:15872]) HSP 1 Score: 234.572 bits (597), Expect = 2.279e-68 Identity = 123/296 (41.55%), Postives = 176/296 (59.46%), Query Frame = 3
Query: 1827 YCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECE 2714
Y L H NRKL +EPK+T+N +I+VVGAS+ G+SFLE+L F H+KFNNL L+S +GLP D + + D F+ K L +L V+VV G MT IDR K + ++ ++PYDH+I+ TG QY +PCPTEA I T +E N RRY+ VP N +N+ FK L ++R+N + E II+YG++ ++Y + T+L++G+ G RIH V+PP + +N+ VE AV L AGV ++ + +AQ+ND P+ I S SFTT P RL+C
Sbjct: 3 YALNHTNRKLTLEPKITVNAKIIVVGASSVGISFLETLVFCSHMKFNNLTLISTHGLPGKKLLDTEQRKFLASDHCFNDKDYALMSLCSWVNVVVGRMTGIDRAAKHVVLSTDEIVPYDHLILCTGQQYQVPCPTEADISQHLTNREVPNSSQRRYT---------GKVPCNHFTLNEEEDCFKALIWIRNNSITTEGNIIVYGNTIDTYTTVETLLNLGVSGSRIHLVQPPPASTITCINNYSVESAVADALGAAGVTMYRDAILAQWNDGLH-PDPIYSASFTTPTKPFRLQCS 288
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Human
Match: CFAP61 (cilia and flagella associated protein 61 [Source:HGNC Symbol;Acc:HGNC:15872]) HSP 1 Score: 228.409 bits (581), Expect = 2.325e-64 Identity = 150/458 (32.75%), Postives = 234/458 (51.09%), Query Frame = 3
Query: 54 MYARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPL-ANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIF-INTDKGKIPENFGTQFTQIKSIT--DYKNWF---ILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPSNDSQTSSTEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNASIRSG----------LNDIPNNFE-------------------------FPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQA 1301
++ RRTES D I+ LI + +FGK N+I ++EKA L+VTL + EI+ A+F DYPN + DW + + + + PLN+LFMH F++ E EI+ TV+ +H+IF I + T F Q+ +I Y+ F I R ++ P L++R A+ ED DDLMPIF TILK+ YGE++LAE+++AQ+++ +V EV G AVGF+SV + +N+ LL+ F L F G P E+ + L+ + S D++ S+ +V E S + A + +++SG L+DI + + G S A IQLF I+E YE RS+DF+ VF LF ++++ +I++P L PEF L++NFV++ P L +LY FH+ L+ N + ++
Sbjct: 14 VHCRRTESQDVYCIKSLIRKFTCKLFGKLNIIYLLEKANLAVTLCNDKEEIMAQATFLDYPN-WNVAKQDDWVSVFRELDSDIPCTPLNTLFMHLFVAVDEYSVGCCKEILRTVYKAVPELHFIFLIVPSYMSLGSTLITVFDQVGNIPCLTYEEDFAVHICHRHSHYPQLHVRKARVEDHDDLMPIFMRYDTILKETYGEYFLAELIEAQDEENHAVVCEVEGTAVGFMSVCSRVNMQLLHECFDLGPFHGLCFPHPDDVLESPQDLSVRRSQDAELRSSSQGSQKIVEELQEPVSPDTMENIQGNIAREAASE-EALTAVQSGNVSEPEDIEKLSDISTGYAQYHHVSSRSLASLVLPEEPVHFRPIYRGASAAFCIQLFCIDEKYEARSLDFMNFVFSLFSDKNFCVISLPHLTPEFFLIQNFVKMVPFNTCTLEQDLYVFHRAGLLKNICLGRS 469
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Human
Match: CFAP61 (cilia and flagella associated protein 61 [Source:HGNC Symbol;Acc:HGNC:15872]) HSP 1 Score: 228.409 bits (581), Expect = 2.325e-64 Identity = 150/458 (32.75%), Postives = 234/458 (51.09%), Query Frame = 3
Query: 54 MYARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPL-ANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIF-INTDKGKIPENFGTQFTQIKSIT--DYKNWF---ILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPSNDSQTSSTEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNASIRSG----------LNDIPNNFE-------------------------FPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQA 1301
++ RRTES D I+ LI + +FGK N+I ++EKA L+VTL + EI+ A+F DYPN + DW + + + + PLN+LFMH F++ E EI+ TV+ +H+IF I + T F Q+ +I Y+ F I R ++ P L++R A+ ED DDLMPIF TILK+ YGE++LAE+++AQ+++ +V EV G AVGF+SV + +N+ LL+ F L F G P E+ + L+ + S D++ S+ +V E S + A + +++SG L+DI + + G S A IQLF I+E YE RS+DF+ VF LF ++++ +I++P L PEF L++NFV++ P L +LY FH+ L+ N + ++
Sbjct: 14 VHCRRTESQDVYCIKSLIRKFTCKLFGKLNIIYLLEKANLAVTLCNDKEEIMAQATFLDYPN-WNVAKQDDWVSVFRELDSDIPCTPLNTLFMHLFVAVDEYSVGCCKEILRTVYKAVPELHFIFLIVPSYMSLGSTLITVFDQVGNIPCLTYEEDFAVHICHRHSHYPQLHVRKARVEDHDDLMPIFMRYDTILKETYGEYFLAELIEAQDEENHAVVCEVEGTAVGFMSVCSRVNMQLLHECFDLGPFHGLCFPHPDDVLESPQDLSVRRSQDAELRSSSQGSQKIVEELQEPVSPDTMENIQGNIAREAASE-EALTAVQSGNVSEPEDIEKLSDISTGYAQYHHVSSRSLASLVLPEEPVHFRPIYRGASAAFCIQLFCIDEKYEARSLDFMNFVFSLFSDKNFCVISLPHLTPEFFLIQNFVKMVPFNTCTLEQDLYVFHRAGLLKNICLGRS 469
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Human
Match: CFAP61 (cilia and flagella associated protein 61 [Source:HGNC Symbol;Acc:HGNC:15872]) HSP 1 Score: 211.846 bits (538), Expect = 1.147e-61 Identity = 110/251 (43.82%), Postives = 154/251 (61.35%), Query Frame = 3
Query: 1200 NFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLN--EHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTF 1946
NFV++ P L +LY FH+ L+ + IR A D ++ ++ + L+++IL DL++++ AR+ + DIEYIRSHYNIEDFIYF+HH R EHGH+ HFA+NPIFR +K FLKE +R K+ +YY VY K N HSL + L LVP+RPRRQI+Y ++KL NAP++ + + Y L H NRKL +EPK+T+N +I+VVGAS+ G+SFLE+L F
Sbjct: 2 NFVKMVPFNTCTLEQDLYVFHRAGLLKSINIRFATLLDTPGVENLVSTLMLNKSILEDLDRYNKARK--------------------------DPDIEYIRSHYNIEDFIYFSHHQREEHGHMHHFALNPIFRHYTKFFLKEILRLGFKSCLYYRVYPKSREGKFQNPYAHSLTSALHYLVPVRPRRQIVYPLEKLGINAPSKAVSKDPMSYALNHTNRKLTLEPKITVNAKIIVVGASSVGISFLETLVF 226
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Fly
Match: CG30268 (gene:FBgn0050268 transcript:FBtr0273311) HSP 1 Score: 99.3673 bits (246), Expect = 1.336e-20 Identity = 159/720 (22.08%), Postives = 286/720 (39.72%), Query Frame = 3
Query: 1545 LRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNEHSLVTNLQDLVPIRPRRQ----ILYDIQKLEGNAPTERI-LQVQEGYCLTH---FNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFS-------PHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFD-------------------FSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESK-IIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPV----DEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTH--GPPLRLECELFVSYYKKVVNYSAFRAMNDSCL-VFDARLVIDTFFHTNDLSIRAAG------PVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTR--------SSPCNASFEETVRNMMVEGV-ELTREQRKELMDEF 3533
L + G I F ++P F+ K L+ +YY + ++ L N+ + +++PI PRR Y L ++ + V C + F L + +++VG S+T ++FL ++ F+ + K+N L ++ L + +IE DF F + ++ +R V V G + +I R++K++ ++ L YD +++ +Y + + FK H +P N +V N V + L ES II+YG++ Y C+H +++ G I +V+P V ++ P D ++ + + + + GV I+ + +QF S + N I V H + L C+LFV+Y ++ S ++++ + + + R+V+++ + TND +I AAG P F+ Y + Q + + + KV ++ Y + + ILP G+ + +++P PL + LTT Y + R+ LN V I C+ KK + G H LN+L RF I++ +FF W HDRF DL+ + + LL++ ++P N S E T R + E V + R RK+ EF
Sbjct: 580 LTHKRGEIVMFRLHPFFQMWCKTILRTVALCDNYRELYYIHF--FSGISLPNDL-----MYNMMPIEPRRMKKNLFNYKCVSLRRRVAKGKMSVNVSMDICTSRMRLFCHNLQPTMHMGGKNSLLIVGFSSTCMAFLRTVIFAWNSKDLINYKKYNCLPMVDITVLVGHG----IIESAYDCDFSCNFCANARNCYVDTGNVNPFVRDTMQRMDVRHWVRFVSGEVKSIKRQEKVVELSDGCHLYYDKLVLMGATRYG-------------------------FEDKEFKGHP---IPLNYVVNNTRLDRIIFYHKVCEMVELMESYYIIVYGYNLCIYECIHFLVTHGCKAQNIIYVQPHVPIVMEDLGIPEKDSRLDPIILEMIADLGVTIYLSTNYSQFILSQDNMN-IEKVELIMHPSKKKIVLHCDLFVNYNDNTISSSMENVLSEAGIEISERRIVVNSRYCTNDRNIFAAGINVIMIPKPNFQYTYGSPQEMAEKLAYEL---NMIKVVMQ--------------------SRYSKPYMFTGILPMGYQIIKITQPK---PLLIGQLPIEFSETLTT---YDDGDFCRIRLNNKLIVIEIVCVTKKPKRLYFMEYFCGKHAMLLNDLRGRFQAGWIQNFLDFFQQPWTELLMHDRFEDLQLKNRRLLLSMLLMNNKDTNNPRN-SLENTQRLRLEENVIDFVRTYRKDFTHEF 1229 HSP 2 Score: 64.3142 bits (155), Expect = 7.037e-10 Identity = 98/486 (20.16%), Postives = 199/486 (40.95%), Query Frame = 3
Query: 81 DAVEIEKLINSNSIYIFG---KPNLINIIEKALLSVTLTSKTGE---IVGYASFYDYPNIAEI--DTSSDWNEIVKLKECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIP------ENFGTQFTQIKS-ITDYKNW---FILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAE-MVDAQ------NDQTKCLVA------EVGGFAVGFISVTTDINIDLLNY--------------------GFYLEAFEGFKKPVQTVNEENIEQLAKKPSNDSQTSSTEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNAL---FRFPSNASIRSGLNDIPNNFEFPGE-SNAIIIQLFAINEAYEMRSIDF-LQNVFDLFPNRDYLLITVPFLVP----EFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSR 1358
D IE L ++ S + FG P L + K + E ++ Y+ F ++PNI + D W + + P+ LN++F ++F+ K + S +L +++ VF T ++Y+ + P + FGT + S +++ K+ +++R + MP L R A ED DD++ + +++ L+ +G+FY+AE +++A+ ND+ V G + ++S + DI + NY GF + + E K + + +E+ K + T + + ++ + + + L F P S N ++ + SN ++++F ++ + L +F FP+ DY + VP V + LL F+ ++ RP + L+ H+ +L ++ + ++ +EI+ +I R
Sbjct: 17 DQRRIEDLYDAKSTWHFGVKETPPLDTLFLKNQAQRLIVYNKQEYHLLLAYSEFANHPNIPVLANDLWLHWLNVRFCVDLPIT-LLNAIFFNFFICK-DGHSQMLKKVILEVFYTEHLVNYMLVFKPPDCPPGQYDAVQAFGTTYYPKHSKVSEQKHLPAVIVIQRRSTMPVLSFRKALPEDNDDIVEMIDSEDPELRKKHGDFYIAEHLLNAEGSDSDHNDKIIIAEFEEEIADNVKGAGLMWLSQSLDIKMLATNYHLERLGNLVRYTPGCTHAHVGFEVISVE-LKSYKELFTRKQMEERYKSHVSRINTDGQDETRNILFKKYKHIYEELREGVYYITAHQDKLEISFDLPDGEKSTS-----ENRLQYLAKASNGFLLKMFQLHPLVRYEYTFYSLSAMFSAFPDHDYCVTLVPANVSTSPCQRELLRFFLPVAHRPSSTVSENLFVAHRSTLFGELRVHRFESQEIDEIRTLISKQARKR 494
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Fly
Match: CG30275 (gene:FBgn0050275 transcript:FBtr0344660) HSP 1 Score: 85.5001 bits (210), Expect = 2.618e-16 Identity = 110/460 (23.91%), Postives = 194/460 (42.17%), Query Frame = 3
Query: 2085 LRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNL--MLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKP------PVD-EEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPP---LRLECELFVSYYKKVVNYSAFRAMNDSCLVFDA-RLVIDTFFHTNDLSIRAAGPVTKFK-RRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELL 3422
LR VH V G + +DR KK + ++ + YD +++ + + C + P P NL+ +N F L VR L M +++YG++ +Y C+ ++ G+ R+ FV+P D +E P D ++ + L E GV+I +Y +N + ++I V F H P + EC+LF+S+ + ++ + + ++ + D +++++ + TND + AAG K + Y ++ R +R + L V + F+ + + +L ILP + V+ P + LS + N LTT Y + + R+ L+ V+ I + KK ++ + G HE LN L+SR+ NLI +FF + W HD F +L+ E KELL
Sbjct: 809 LRCWVHFVPGKVEKVDRDKKFVKLDSCEIY-YDTLLLMCDRMFVLRCI------DVPVYSPR---------------------PCNLVEINFRLNKFLLFYKVRALLEDMPRTYLVLVYGNNLHTYECIAFLIGHGVDCSRMVFVQPHRITGRDADMKEKCPYWDKNLQMIMDDILVEKGVNIFTDYDFHHYN-LHKSTDFIMEVIFQ-HFPTQKQMTFECDLFISFQEGHLHQRHKQWLENAGIELDGNQILVNERYQTNDPDVYAAGSFIKMRITPNYQYKFVSERELARKILHHLGIVTDKNFEDR-----------------FAEPVLFQAILPLRYFITKVTMPRRYL-LSQVPVIKNCN--LTT---YKNKTFCRVGLSTRMMVDEIVVVTKKECNLDFLLYFCGKHELLLNKLKSRYRANLIHCFLKFFQEPWTELIMHDDFEELQAENKELL 1215 HSP 2 Score: 70.4774 bits (171), Expect = 8.815e-12 Identity = 68/278 (24.46%), Postives = 128/278 (46.04%), Query Frame = 3
Query: 63 RRTESLDAVEIEKLINSNSIYIFG--------KPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPLAN--PLNSLFMHYFLSKPEVESNILMEIVNTVFNTASN---------------IHYIFINTDKGKIPENFGTQFTQIKSITDYKNWFILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEV------GGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPV 803
R ++ D + KLI S + FG K +L N + + + +++ +V YA F +YP+IA + T W E + + C + LN+LF ++ + K + +S +L+EI+ V S IH++ D KI + F + + ++ +I+ R +P + R A ED DD++ + ++ +++ G++Y+AE V QN ++ +VAE A+ F+ +++DI+I + +E F KP
Sbjct: 7 RLAQAGDQDGLNKLIRSPGVKWFGNIRPKFRGKDSLFNSYQTYRI-LAFCTESSALVAYAEFRNYPSIAALPTDC-WLEWLSTRYCLSMSISWLNALFFNFCVYKSD-QSPVLVEIIKDVLYRESRVWFLITVRCPYVPQPIHFVETFDDLEKISQVFYPLEYSMDKNNNTQSLYIVDRFVILPRITYRKALAEDNDDIIAMQEVENPEMREELGDYYIAEEVMGQNPKSMLVVAETINQSQESEMAI-FLWLSSDIDIMFYVRNYEMEQFGNLVKPA 280
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Fly
Match: CG30275 (gene:FBgn0050275 transcript:FBtr0344659) HSP 1 Score: 85.5001 bits (210), Expect = 2.630e-16 Identity = 110/460 (23.91%), Postives = 194/460 (42.17%), Query Frame = 3
Query: 2085 LRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNL--MLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKP------PVD-EEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPP---LRLECELFVSYYKKVVNYSAFRAMNDSCLVFDA-RLVIDTFFHTNDLSIRAAGPVTKFK-RRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELL 3422
LR VH V G + +DR KK + ++ + YD +++ + + C + P P NL+ +N F L VR L M +++YG++ +Y C+ ++ G+ R+ FV+P D +E P D ++ + L E GV+I +Y +N + ++I V F H P + EC+LF+S+ + ++ + + ++ + D +++++ + TND + AAG K + Y ++ R +R + L V + F+ + + +L ILP + V+ P + LS + N LTT Y + + R+ L+ V+ I + KK ++ + G HE LN L+SR+ NLI +FF + W HD F +L+ E KELL
Sbjct: 796 LRCWVHFVPGKVEKVDRDKKFVKLDSCEIY-YDTLLLMCDRMFVLRCI------DVPVYSPR---------------------PCNLVEINFRLNKFLLFYKVRALLEDMPRTYLVLVYGNNLHTYECIAFLIGHGVDCSRMVFVQPHRITGRDADMKEKCPYWDKNLQMIMDDILVEKGVNIFTDYDFHHYN-LHKSTDFIMEVIFQ-HFPTQKQMTFECDLFISFQEGHLHQRHKQWLENAGIELDGNQILVNERYQTNDPDVYAAGSFIKMRITPNYQYKFVSERELARKILHHLGIVTDKNFEDR-----------------FAEPVLFQAILPLRYFITKVTMPRRYL-LSQVPVIKNCN--LTT---YKNKTFCRVGLSTRMMVDEIVVVTKKECNLDFLLYFCGKHELLLNKLKSRYRANLIHCFLKFFQEPWTELIMHDDFEELQAENKELL 1202 HSP 2 Score: 66.6254 bits (161), Expect = 1.575e-10 Identity = 66/267 (24.72%), Postives = 128/267 (47.94%), Query Frame = 3
Query: 63 RRTESLDAVEIEKLINSNSIYIFG--------KPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPLAN--PLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIPE--NFGTQFTQIKSITD--YKNWFILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEV------GGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPV 803
R ++ D + KLI S + FG K +L N + + + +++ +V YA F +YP+IA + T W E + + C + LN+LF ++ + K + +S +L+EI+ V S + + I +P+ +F F ++ I+ Y + + + +LYI + ED DD++ + ++ +++ G++Y+AE V QN ++ +VAE A+ F+ +++DI+I + +E F KP
Sbjct: 7 RLAQAGDQDGLNKLIRSPGVKWFGNIRPKFRGKDSLFNSYQTYRI-LAFCTESSALVAYAEFRNYPSIAALPTDC-WLEWLSTRYCLSMSISWLNALFFNFCVYKSD-QSPVLVEIIKDVLYRESRV-WFLITVRCPYVPQPIHFVETFDDLEKISQVFYPLEYSMDKNNNTQSLYI-VDRAEDNDDIIAMQEVENPEMREELGDYYIAEEVMGQNPKSMLVVAETINQSQESEMAI-FLWLSSDIDIMFYVRNYEMEQFGNLVKPA 267
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Fly
Match: CG30275 (gene:FBgn0050275 transcript:FBtr0344661) HSP 1 Score: 65.4698 bits (158), Expect = 7.459e-11 Identity = 66/267 (24.72%), Postives = 129/267 (48.31%), Query Frame = 3
Query: 63 RRTESLDAVEIEKLINSNSIYIFG--------KPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPLAN--PLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIPE--NFGTQFTQIKSITD--YKNWFILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEV------GGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPV 803
R ++ D + KLI S + FG K +L N + + + +++ +V YA F +YP+IA + T W E + + C + LN+LF ++ + K + +S +L+EI+ V S + ++ I +P+ +F F ++ I+ Y + + + +LYI + ED DD++ + ++ +++ G++Y+AE V QN ++ +VAE A+ F+ +++DI+I + +E F KP
Sbjct: 7 RLAQAGDQDGLNKLIRSPGVKWFGNIRPKFRGKDSLFNSYQTYRI-LAFCTESSALVAYAEFRNYPSIAALPTDC-WLEWLSTRYCLSMSISWLNALFFNFCVYKSD-QSPVLVEIIKDVLYRESRVWFL-ITVRCPYVPQPIHFVETFDDLEKISQVFYPLEYSMDKNNNTQSLYI-VDRAEDNDDIIAMQEVENPEMREELGDYYIAEEVMGQNPKSMLVVAETINQSQESEMAI-FLWLSSDIDIMFYVRNYEMEQFGNLVKPA 267
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Zebrafish
Match: si:zfos-223e1.2 (si:zfos-223e1.2 [Source:ZFIN;Acc:ZDB-GENE-110411-269]) HSP 1 Score: 327.791 bits (839), Expect = 3.499e-99 Identity = 197/558 (35.30%), Postives = 311/558 (55.73%), Query Frame = 3
Query: 1977 LLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRP-SLDIPLSTLTNQPNYGSVLTTGVPYCQE--GYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMT---RSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
L+S + LPD H +D+ L + + ++S L + VV G + AI+R K + + + +D++I+ TG+QY +P + N ++ N + K VP NL ++ND ++ HN ++YG++ + + C+ T++ +G+ G RIH V PP D+ D VE AV + L++ VH+H N + Q ND ++S SF+T G L+LEC +F S+ +K V+ AFRA+ND+CLVFD RLV+D+ FHTND SI AAGP+TK+ RRY+ E+WSH F S+ VG+ L+ V L DPTL V PP +++ LIP+Y + + LPGG++YL V++P + P + + G L TG C E YF + +Q+ VE ITCL K P+ N LYG H+R LNN+ SR++E LI+D++ +F + W +A YHDRF D ++E+ +++ + + + S EE ++ + + E +Q L F+ S A S + ++ ++ YN YHL MYA+P ++
Sbjct: 1 LISTHALPD-HSSDDCSTFLATSHCYNDRDQCQIS-LCSWISVVTGKIKAINRADKHVELMDDSRVKFDYLILCTGLQYQMP-----NLSNADVITQTSNS--------LKPKETRPRVPSNLFLLNDHQDCSVAHHWLTHNFTQLTGDAVVYGNTIDVFTCIETLIGLGVSGRRIHVVHPPEDQPFSCFPDASVELAVKQALEKEEVHVHHNCLLLQINDGQHTEP-VTSASFSTDGAILQLECAVFFSFSRKSVDCDAFRAINDACLVFDGRLVVDSGFHTNDPSIYAAGPMTKYSRRYHAEEWSHCCFQSKEVGQSLASVLLAQCDPTLERPVDPPPDQLHLIPLYSQAKTQGGRLPGGYNYLHVAKPVARKTPSAHKVCFTSTGRDLVTG---CAETGNYFHIRHSQFDVVEKITCLSKTPLPVSNLQSLYGKHQRLLNNICSRYDEGLIQDMYSYFKENWCLALYHDRFADFEQEVCQIMDSAKLQDESGSVSLEEALQQIADDKAE--SDQLVSLSQTFQKSQAYSALRNSVLDYLKYNRYHLSMYARPGLL 537
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Xenopus
Match: cfap61 (cilia and flagella associated protein 61 [Source:NCBI gene;Acc:779967]) HSP 1 Score: 612.068 bits (1577), Expect = 0.000e+0 Identity = 331/869 (38.09%), Postives = 505/869 (58.11%), Query Frame = 3
Query: 1035 FPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLN--EHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILK-SCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
+ G+ A IQLF I+E +E RS+DFL F LFP++D+ +ITVP L PEF LL+NFVR+ P L ELY FH+ +LIS+ K+R D I+ ++ + +IL DL+ ++ ARR D G + A+VAE N+IVGV V++ E+DIEYI SHYNIEDFIYF HH EHGH+ HFA+NPIF + FLKE +R S K+++YYP+Y ++ N HSL + L +VP+RPRRQI++ ++KL NAP++++ + Q Y L HFNRKL +EPKVTIN RIVVVGAS G+SF+E+L F PHLKFNN+ L+S GLP+N P + ++ K L +LR V+VV G M+ IDR K + + +PYDH+I+ TG QY +PCPTEA ++ T KE+ ++RY+ +P NL + + + F++ +++ E K+I Y + + +++++G+ G RI V P + +N ++ ++ + ++ + + V F+ + P+ +F P R + + F ++ +K V+Y AF+A+ND+CLV+D RLVIDT FHTND SIRAAG +TK+ RY+ +WSH+ F+S+ +G +L+ L +FDPTL PV+ E LIPIY +++ S I+PGG HYL + P I L + Q G GYF L Y ++T K + + + H R L +L +RF+ L+ +F + W MA YHDRF D ++E++E+L S ++ + + + + L + R+ L + K +++++++++ YN HL M+A+P M+
Sbjct: 381 YKGDVTAFSIQLFCIDEKHESRSVDFLSYAFSLFPDKDFCVITVPHLTPEFPLLQNFVRVVPLSTCTLSQELYVFHRAALISSIKVRAVRSNDIHNIRSLLETLHPQESILGDLQIYNQARRDDDGTPVQAFVAEVANQIVGVSVIRNEKDIEYIHSHYNIEDFIYFNHHQWEEHGHLHHFALNPIFMHFGRHFLKEILRLSHKSALYYPIYPSCNKEQFKNPCAHSLSSALHYMVPVRPRRQIVFPLEKLGINAPSKQVSKDQPSYSLNHFNRKLTLEPKVTINARIVVVGASEVGISFMETLVFCPHLKFNNITLISSTGLPENTPISTQEHGFLSTSHSYNDKDYALMSLRSWVNVVVGKMSGIDRAAKFVIVANGRKVPYDHLILCTGQQYQVPCPTEADVRKLLTNKEAPVSSNQRYT---------GKIPSNLFTLQNRQDCLAAMRFLKDSVVKQEGKVISYENRSDMQLISSSVIALGVSGCRIRMVSPKLHFNTCCINRYKIKTSITAGIGNEDINAYADCAVPSFSAGNH-PHPACMGTFRNVTTPCRKQIQAFFNFSRKSVDYEAFKAINDACLVYDGRLVIDTTFHTNDDSIRAAGTLTKYSNRYHASEWSHSNFSSKEIGFQLAANMLNIFDPTLEPVIEFTDEFDRLIPIYKGPVIQASGIIPGG-HYLHANLPVQPIQLRSQFKQARSGRAAIKD-SQTAGGYFFLKTKMYHMAISLTSSSGKPFQESKPICMSCHHLRLLESLIARFSNRLLNSENSYFMEAWCMAIYHDRFIDFQQEVREMLAAEQGEGRPSMKQLAQQIADDELNLKEQPRQYLKRILEENGHKKEIERKILNYLNYNSNHLSMFARPGMI 1237 HSP 2 Score: 174.096 bits (440), Expect = 2.807e-43 Identity = 105/284 (36.97%), Postives = 161/284 (56.69%), Query Frame = 3
Query: 63 RRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPLAN--PLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGK-IPENFGTQFTQIK-----SITDYKNWFILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKP-----VQTVNEENIEQLAKKPSNDSQTSST 875
RRTESLD I K + + IFG+ N+I ++EKA L+VT+ S +V A DYPN +D ++W E + L+N PLN+LF+H F++K E + EI+ VFNTA +H+I + + + + G+ F Q K ++ + ++ R + P LY+R A+ ED DDL+PIF + LK YGEF+LAE+++AQ++Q+ +V+E G AVGF+SV+++IN LL F L F G KP + + +IE+ DS+TS+
Sbjct: 17 RRTESLDVHGIIKRKTTTTERIFGRVNVIYLLEKANLAVTVYSAKNGVVANAVLLDYPNCDIVD-QAEWEEKLPTHYEELSNCTPLNTLFLHLFVAKDEYSEQCIQEIIRVVFNTAPYLHFICLTAPRDEALGLALGSVFQQTKIVSASALAKQHSLYMCHRHNHCPQLYVRNARVEDYDDLIPIFMRHNDTLKATYGEFFLAELIEAQDEQSHAIVSEDKGKAVGFMSVSSEINARLLQSCFDLGPFHGLCKPHPDDILYASEKTSIEKDLMLSRQDSKTSAA 299
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Xenopus
Match: cfap61 (cilia and flagella associated protein 61 [Source:NCBI gene;Acc:779967]) HSP 1 Score: 422.165 bits (1084), Expect = 5.944e-128 Identity = 208/465 (44.73%), Postives = 293/465 (63.01%), Query Frame = 3
Query: 1035 FPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLN--EHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESK 2423
+ G+ A IQLF I+E +E RS+DFL F LFP++D+ +ITVP L PEF LL+NFVR+ P L ELY FH+ +LIS+ K+R D I+ ++ + +IL DL+ ++ ARR D G + A+VAE N+IVGV V++ E+DIEYI SHYNIEDFIYF HH EHGH+ HFA+NPIF + FLKE +R S K+++YYP+Y ++ N HSL + L +VP+RPRRQI++ ++KL NAP++++ + Q Y L HFNRKL +EPKVTIN RIVVVGAS G+SF+E+L F PHLKFNN+ L+S GLP+N P + ++ K L +LR V+VV G M+ IDR K + + +PYDH+I+ TG QY +PCPTEA ++ T KE+ ++RY+ +P NL + + + F++ +++ E K
Sbjct: 381 YKGDVTAFSIQLFCIDEKHESRSVDFLSYAFSLFPDKDFCVITVPHLTPEFPLLQNFVRVVPLSTCTLSQELYVFHRAALISSIKVRAVRSNDIHNIRSLLETLHPQESILGDLQIYNQARRDDDGTPVQAFVAEVANQIVGVSVIRNEKDIEYIHSHYNIEDFIYFNHHQWEEHGHLHHFALNPIFMHFGRHFLKEILRLSHKSALYYPIYPSCNKEQFKNPCAHSLSSALHYMVPVRPRRQIVFPLEKLGINAPSKQVSKDQPSYSLNHFNRKLTLEPKVTINARIVVVGASEVGISFMETLVFCPHLKFNNITLISSTGLPENTPISTQEHGFLSTSHSYNDKDYALMSLRSWVNVVVGKMSGIDRAAKFVIVANGRKVPYDHLILCTGQQYQVPCPTEADVRKLLTNKEAPVSSNQRYT---------GKIPSNLFTLQNRQDCLAAMRFLKDSVVKQEGK 836 HSP 2 Score: 173.711 bits (439), Expect = 2.604e-43 Identity = 105/284 (36.97%), Postives = 161/284 (56.69%), Query Frame = 3
Query: 63 RRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPLAN--PLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGK-IPENFGTQFTQIK-----SITDYKNWFILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKP-----VQTVNEENIEQLAKKPSNDSQTSST 875
RRTESLD I K + + IFG+ N+I ++EKA L+VT+ S +V A DYPN +D ++W E + L+N PLN+LF+H F++K E + EI+ VFNTA +H+I + + + + G+ F Q K ++ + ++ R + P LY+R A+ ED DDL+PIF + LK YGEF+LAE+++AQ++Q+ +V+E G AVGF+SV+++IN LL F L F G KP + + +IE+ DS+TS+
Sbjct: 17 RRTESLDVHGIIKRKTTTTERIFGRVNVIYLLEKANLAVTVYSAKNGVVANAVLLDYPNCDIVD-QAEWEEKLPTHYEELSNCTPLNTLFLHLFVAKDEYSEQCIQEIIRVVFNTAPYLHFICLTAPRDEALGLALGSVFQQTKIVSASALAKQHSLYMCHRHNHCPQLYVRNARVEDYDDLIPIFMRHNDTLKATYGEFFLAELIEAQDEQSHAIVSEDKGKAVGFMSVSSEINARLLQSCFDLGPFHGLCKPHPDDILYASEKTSIEKDLMLSRQDSKTSAA 299 HSP 3 Score: 100.138 bits (248), Expect = 1.426e-20 Identity = 64/129 (49.61%), Postives = 86/129 (66.67%), Query Frame = 3
Query: 2742 VNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCIL-PGGHHYL-SVSRPSLDIPLSTLTN 3122
V+Y AF+A+ND+CLV+D RLVIDT FHTND SIRAAG +TK+ RY+ +WSH+ F+S+ +G +L+ L +FDPTL PV+ E LIPIY +++ GG HYL + R SLD +S N
Sbjct: 846 VDYEAFKAINDACLVYDGRLVIDTTFHTNDDSIRAAGTLTKYSNRYHASEWSHSNFSSKEIGFQLAANMLNIFDPTLEPVIEFTDEFDRLIPIYKGPVIQGLWYHSGGLHYLHPLMRGSLDNSISPFEN 974 HSP 4 Score: 65.4698 bits (158), Expect = 6.472e-10 Identity = 26/96 (27.08%), Postives = 54/96 (56.25%), Query Frame = 3
Query: 3345 FFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
+F + W MA YHDRF D ++E++E+L S ++ + + + + L + R+ L + K +++++++++ YN HL M+A+P M+
Sbjct: 976 YFMEAWCMAIYHDRFIDFQQEVREMLAAEQGEGRPSMKQLAQQIADDELNLKEQPRQYLKRILEENGHKKEIERKILNYLNYNSNHLSMFARPGMI 1071
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Xenopus
Match: ENSXETT00000049348.1 (cilia- and flagella-associated protein 61-like [Source:NCBI gene;Acc:108647660]) HSP 1 Score: 273.092 bits (697), Expect = 1.886e-81 Identity = 150/316 (47.47%), Postives = 209/316 (66.14%), Query Frame = 3
Query: 2394 RHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLF 3341
R+NL+ +I+YG++ + Y L T+LS+GI G RIH V+PP+ V N+ +EEAV K L G+ + N +AQ+ND P+ I +FT+ PLRL+C F ++ +K V+Y AF+A+ND+CLV+D RLVIDT FHTND SIRAAG +TK+ RY+ +WSH+ F+S+ +G +L+ L +FDPTL PV+ E LIPIY +++ I+PGG HYL V++P++ PL Q +YG + TG YFRLH+NQY VE+ITCL +K +P NY+ LYG HER LNNL +RF+E LIKDL+
Sbjct: 56 RNNLVCC-CNVIVYGNTLDCYTTLSTLLSLGISGSRIHLVQPPLTMNVTCFNNYAIEEAVQKALLAEGISSYCNCVLAQWNDGAH-PDPICFATFTSDTKPLRLQCSAFFNFSRKSVDYEAFKAINDACLVYDGRLVIDTTFHTNDDSIRAAGTLTKYSNRYHASEWSHSNFSSKEIGFQLAANMLNIFDPTLEPVIEFTDEFDRLIPIYKGPVIQGGIIPGGFHYLHVNKPAIPCPLKAQMAQAHYGREIVTGSAV-DGDYFRLHINQYNMVESITCLSQKPFPESNYICLYGHHERLLNNLCARFDEGLIKDLY 368
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Mouse
Match: Cfap61 (cilia and flagella associated protein 61 [Source:MGI Symbol;Acc:MGI:1926024]) HSP 1 Score: 872.463 bits (2253), Expect = 0.000e+0 Identity = 500/1235 (40.49%), Postives = 743/1235 (60.16%), Query Frame = 3
Query: 54 MYARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKL--KECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIF-INTDKGKIPENFGTQFTQIKSIT--DYKNWF---ILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPS-NDSQTSSTEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNASIRSGLNDIPNNFE------------------------------FPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLN--EHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEG-YFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
++ RRTES D I+ L+ + +FG+ N+I ++EKA L+VT+ + EI+ ++ F DYPN + +W + + KE P PLN+LFMH+F++ E + L EI+ TVF +++IF I + T F Q+ +I +Y F I R + P L+IR A+ ED DDLMPIF LK+IYGE++LAE+++AQ+ +V EV G AVGF+SV T +N+ LL+ F L F GF P + ++I + +++PS + + + ++ S VV +E E TE S S AL S D+ N + G+ A IQLF I+E YE RS+DF+ VF LFP +++ LI+VP L PEF L++NFV++ P L H+LY FH+ L+ + IR A D ++ ++ + LS IL+DL Q++ A R G +L +VAE ++IVG+ V+++E DIEYIRSHYNIEDFIYF+HH + EHG + HFA+NPIFR +K FLKE +R K+ +YYPVY KL + HSL + L LVP+RPRRQI+Y ++KL NAP++ + + Q + L H NRKL +EPKVT+N RIVVVGAS+ G+SFLE+L F HLKFNNL L+S +GLP + + D F+ K L +L V+VV G MTAIDR K + ++ ++ YDH+I+ TG+QY +PCPT A + T +E +RY+ VP NL ++ND ++L ++R++ +L E K+I+YG++ ++Y + T+L++G+ G I+FV PP + + +N+ VE AV L AGV + + +AQ+N P+ I + FTT P+RLEC F S+YKK V+Y F+A ND+CLV+D RLVIDT FHTND++IRAAG +TKF RYY+ +W+H+ F+S+ +G +L+ L LFDPTL PV PP + LIP+Y + ++ ILPG +HYL +S+P++ PL+ +QP++GS + TG ++G YFRL++N YK VE ITC K+ +P NY++L+G HE+ LNNL +RF++ LI DL+ +F + W MA +HDRF DLK+E++++L+++ + EE + E + L + +K L F +S KS +++ ++ ++ YN YHLPMYA P ++
Sbjct: 14 VHCRRTESQDIFCIKNLVRKFTQKLFGRLNIIYLLEKANLAVTVCNDKEEIMAHSIFLDYPN-WNVAKQDNWIPLFRELDKEIP-CTPLNTLFMHFFVAVDEYATGCLKEIIRTVFKAVPELYFIFLIVPTYLSLGSTLITVFDQVGNIPCLNYNEDFAVHICHRHNHYPQLHIRKARVEDHDDLMPIFMHYDNTLKEIYGEYFLAELIEAQDKDHHAVVCEVEGKAVGFMSVCTSVNLPLLHECFDLGPFHGFCTP----HPDDILKPSREPSLEEGEDAESQGSPKVVEEQEMAPEITQEKETETSASCEEALPTVLGLVSEERLKQDMEKNLSILSLVDEEDVASSLSSSLLLSVESSHFRPLYLGDPIAFCIQLFCIDERYEARSLDFMSFVFSLFPGKNFCLISVPHLTPEFVLIQNFVKVVPFNNCTLDHDLYVFHRAGLLRSITIRLAKFLDTAGVEKLVSTLLLSTKILDDLAQYNEAGRDPDGTALQVFVAEVADQIVGIAVIRKEMDIEYIRSHYNIEDFIYFSHHQQEEHGRLNHFALNPIFRHYTKFFLKEILRLGYKSCLYYPVYPQTREGKLQSSYSHSLTSALHYLVPVRPRRQIVYPLEKLGINAPSKEVSKDQVSFALNHTNRKLTLEPKVTVNARIVVVGASSVGISFLETLVFCSHLKFNNLTLISTHGLPGKRLLHNEQRKFLASDHCFNDKDYALMSLCSWVNVVVGRMTAIDRAAKQVVVSKSEIVFYDHLILCTGLQYQVPCPTGADTEQHLTNREVLELSKQRYT---------GTVPSNLFILNDEEDCVRMLCWLRNSSILTEGKVIVYGNTLDAYTTVETLLNIGMKGSGIYFVHPPTESNITCINNNDVESAVEDALSAAGVTVFHDALLAQWNHGQH-PDPIYNACFTTSTKPIRLECSAFFSFYKKNVDYETFKAFNDACLVYDGRLVIDTTFHTNDIAIRAAGSLTKFSNRYYSNEWTHSNFSSKEIGFQLAAAMLSLFDPTLEPVTEPPADLDRLIPMYKGAKIQGGILPGSYHYLHISKPAIPTPLNLQRSQPDFGSDVVTG--NAKKGTYFRLYINNYKLVEAITCFSKEPFPSSNYIRLFGQHEQVLNNLCTRFDDKLIPDLYSYFTEPWCMALFHDRFIDLKKELRQILISKQEEDKPTMEEIAYRLEEEEINLNEKPQKYLQRVFEDSIYKSLLEKSILDYLHYNQYHLPMYAWPGII 1230
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Mouse
Match: Cfap61 (cilia and flagella associated protein 61 [Source:MGI Symbol;Acc:MGI:1926024]) HSP 1 Score: 358.607 bits (919), Expect = 1.714e-109 Identity = 223/590 (37.80%), Postives = 327/590 (55.42%), Query Frame = 3
Query: 54 MYARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKL--KECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIF-INTDKGKIPENFGTQFTQIKSI--TDYKNWF---ILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPS-NDSQTSSTEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNASIRSGLNDIPNNFE------------------------------FPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNEH 1706
++ RRTES D I+ L+ + +FG+ N+I ++EKA L+VT+ + EI+ ++ F DYPN + +W + + KE P PLN+LFMH+F++ E + L EI+ TVF +++IF I + T F Q+ +I +Y F I R + P L+IR A+ ED DDLMPIF LK+IYGE++LAE+++AQ+ +V EV G AVGF+SV T +N+ LL+ F L F GF P + ++I + +++PS + + + ++ S VV +E E TE S S AL S D+ N + G+ A IQLF I+E YE RS+DF+ VF LFP +++ LI+VP L PEF L++NFV++ P L H+LY FH+ L+ + IR A D ++ ++ + LS IL+DL Q++ A R G +L +VAE ++IVG+ V+++E DIEYIRSHYNIEDFIYF+HH + EHG + HFA+NPIFR +K FLKE +R K+ +YYPVY K+ H
Sbjct: 14 VHCRRTESQDIFCIKNLVRKFTQKLFGRLNIIYLLEKANLAVTVCNDKEEIMAHSIFLDYPN-WNVAKQDNWIPLFRELDKEIP-CTPLNTLFMHFFVAVDEYATGCLKEIIRTVFKAVPELYFIFLIVPTYLSLGSTLITVFDQVGNIPCLNYNEDFAVHICHRHNHYPQLHIRKARVEDHDDLMPIFMHYDNTLKEIYGEYFLAELIEAQDKDHHAVVCEVEGKAVGFMSVCTSVNLPLLHECFDLGPFHGFCTP----HPDDILKPSREPSLEEGEDAESQGSPKVVEEQEMAPEITQEKETETSASCEEALPTVLGLVSEERLKQDMEKNLSILSLVDEEDVASSLSSSLLLSVESSHFRPLYLGDPIAFCIQLFCIDERYEARSLDFMSFVFSLFPGKNFCLISVPHLTPEFVLIQNFVKVVPFNNCTLDHDLYVFHRAGLLRSITIRLAKFLDTAGVEKLVSTLLLSTKILDDLAQYNEAGRDPDGTALQVFVAEVADQIVGIAVIRKEMDIEYIRSHYNIEDFIYFSHHQQEEHGRLNHFALNPIFRHYTKFFLKEILRLGYKSCLYYPVYPQTREGKVRGWH 597
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Mouse
Match: Cfap61 (cilia and flagella associated protein 61 [Source:MGI Symbol;Acc:MGI:1926024]) HSP 1 Score: 212.231 bits (539), Expect = 4.917e-61 Identity = 113/300 (37.67%), Postives = 172/300 (57.33%), Query Frame = 3
Query: 1731 LVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNE--------------------------SKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLND 2552
LVP+RPRRQI+Y ++KL NAP++ + + Q + L H NRKL +EPKVT+N RIVVVGAS+ G+SFLE+L F HLKFNNL L+S +GLP + + D F+ K L +L V+VV G MTAIDR K + ++ ++ YDH+I+ TG+QY +PCPT A + T +E +RY+ VP NL ++ND ++L ++R++ +L E K+I+YG++ ++Y + T+L++G+ G I+FV PP + + +N+
Sbjct: 1 LVPVRPRRQIVYPLEKLGINAPSKEVSKDQVSFALNHTNRKLTLEPKVTVNARIVVVGASSVGISFLETLVFCSHLKFNNLTLISTHGLPGKRLLHNEQRKFLASDHCFNDKDYALMSLCSWVNVVVGRMTAIDRAAKQVVVSKSEIVFYDHLILCTGLQYQVPCPTGADTEQHLTNREVLELSKQRYT---------GTVPSNLFILNDEEDCVRMLCWLRNSSILTEVPTLLQTPPCCYWTMQNHLSTVNPRTGKVIVYGNTLDAYTTVETLLNIGMKGSGIYFVHPPTESNITCINN 291
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Mouse
Match: Cfap61 (cilia and flagella associated protein 61 [Source:MGI Symbol;Acc:MGI:1926024]) HSP 1 Score: 138.272 bits (347), Expect = 1.044e-35 Identity = 84/224 (37.50%), Postives = 128/224 (57.14%), Query Frame = 3
Query: 54 MYARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKL--KECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIF-INTDKGKIPENFGTQFTQIKSI--TDYKNWF---ILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVG 701
++ RRTES D I+ L+ + +FG+ N+I ++EKA L+VT+ + EI+ ++ F DYPN + +W + + KE P PLN+LFMH+F++ E + L EI+ TVF +++IF I + T F Q+ +I +Y F I R + P L+IR A+ ED DDLMPIF LK+IYGE++LAE+++AQ+ +V EVG
Sbjct: 14 VHCRRTESQDIFCIKNLVRKFTQKLFGRLNIIYLLEKANLAVTVCNDKEEIMAHSIFLDYPN-WNVAKQDNWIPLFRELDKEIP-CTPLNTLFMHFFVAVDEYATGCLKEIIRTVFKAVPELYFIFLIVPTYLSLGSTLITVFDQVGNIPCLNYNEDFAVHICHRHNHYPQLHIRKARVEDHDDLMPIFMHYDNTLKEIYGEYFLAELIEAQDKDHHAVVCEVG 235
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Mouse
Match: Cfap61 (cilia and flagella associated protein 61 [Source:MGI Symbol;Acc:MGI:1926024]) HSP 1 Score: 92.4337 bits (228), Expect = 8.664e-21 Identity = 62/181 (34.25%), Postives = 98/181 (54.14%), Query Frame = 3
Query: 54 MYARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKL--KECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIF-INTDKGKIPENFGTQFTQIKSI--TDYKNWF---ILKREAYMPTLYIRAAKQED 572
++ RRTES D I+ L+ + +FG+ N+I ++EKA L+VT+ + EI+ ++ F DYPN + +W + + KE P PLN+LFMH+F++ E + L EI+ TVF +++IF I + T F Q+ +I +Y F I R + P L+IR A+ ED
Sbjct: 14 VHCRRTESQDIFCIKNLVRKFTQKLFGRLNIIYLLEKANLAVTVCNDKEEIMAHSIFLDYPN-WNVAKQDNWIPLFRELDKEIP-CTPLNTLFMHFFVAVDEYATGCLKEIIRTVFKAVPELYFIFLIVPTYLSLGSTLITVFDQVGNIPCLNYNEDFAVHICHRHNHYPQLHIRKARVED 192
BLAST of cilia- and flagella-associated protein 61 vs. UniProt/SwissProt
Match: sp|Q8NHU2|CFA61_HUMAN (Cilia- and flagella-associated protein 61 OS=Homo sapiens OX=9606 GN=CFAP61 PE=2 SV=3) HSP 1 Score: 885.56 bits (2287), Expect = 0.000e+0 Identity = 497/1238 (40.15%), Postives = 736/1238 (59.45%), Query Frame = 3
Query: 54 MYARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPL-ANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIF-INTDKGKIPENFGTQFTQIKSIT--DYKNWF---ILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPSNDSQTSSTEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNASIRSG----------LNDIPNNFE-------------------------FPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLN--EHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEG-YFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
++ RRTES D I+ LI + +FGK N+I ++EKA L+VTL + EI+ A+F DYPN + DW + + + + PLN+LFMH F++ E EI+ TV+ +H+IF I + T F Q+ +I Y+ F I R ++ P L++R A+ ED DDLMPIF TILK+ YGE++LAE+++AQ+++ +V EV G AVGF+SV + +N+ LL+ F L F G P E+ + L+ + S D++ S+ +V E S + A + +++SG L+DI + + G S A IQLF I+E YE RS+DF+ VF LF ++++ +I++P L PEF L++NFV++ P L +LY FH+ L+ + IR A D ++ ++ + L+++IL DL++++ AR+ G L A+VAE +IVG+ V++ E DIEYIRSHYNIEDFIYF+HH R EHGH+ HFA+NPIFR +K FLKE +R K+ +YY VY K N HSL + L LVP+RPRRQI+Y ++KL NAP++ + + Y L H NRKL +EPK+T+N +I+VVGAS+ G+SFLE+L F H+KFNNL L+S +GLP D + + D F+ K L +L V+VV G MT IDR K + ++ ++PYDH+I+ TG QY +PCPTEA I T +E N RRY+ VP N +N+ FK L ++R+N + E II+YG++ ++Y + T+L++G+ G RIH V+PP + +N+ VE AV L AGV ++ + +AQ+ND P+ I S SFTT P RL+C +F S+ +K V+Y F+A+ND+CLV+D+RLVIDT FHTND++IRAAG +TKF RYY+ +W+H+ F+S+ +G +L+ L LFDPTL PV PP LIP+Y + ++ ILPG +HYL +++P++ PL QPNYG L TG + G YFR+H+N+YK VETITCL ++ +P NY++L+G HE+ LNNL +R++ENLI DL+ +F + W +A +HDRF DL++E++++L ++ S E+ + E + T + R+ L F S K+ V++ + ++ YN YHLPMYA P +V
Sbjct: 14 VHCRRTESQDVYCIKSLIRKFTCKLFGKLNIIYLLEKANLAVTLCNDKEEIMAQATFLDYPN-WNVAKQDDWVSVFRELDSDIPCTPLNTLFMHLFVAVDEYSVGCCKEILRTVYKAVPELHFIFLIVPSYMSLGSTLITVFDQVGNIPCLTYEEDFAVHICHRHSHYPQLHVRKARVEDHDDLMPIFMRYDTILKETYGEYFLAELIEAQDEENHAVVCEVEGTAVGFMSVCSRVNMQLLHECFDLGPFHGLCFPHPDDVLESPQDLSVRRSQDAELRSSSQGSQKIVEELQEPVSPDTMENIQGNIAREAASE-EALTAVQSGNVSEPEDIEKLSDISTGYAQYHHVSSRSLASLVLPEEPVHFRPIYRGASAAFCIQLFCIDEKYEARSLDFMNFVFSLFSDKNFCVISLPHLTPEFFLIQNFVKMVPFNTCTLEQDLYVFHRAGLLKSINIRFATLLDTPGVENLVSTLMLNKSILEDLDRYNKARKDPDGTLLQAFVAEVAEQIVGIAVIRNEMDIEYIRSHYNIEDFIYFSHHQREEHGHMHHFALNPIFRHYTKFFLKEILRLGFKSCLYYRVYPKSREGKFQNPYAHSLTSALHYLVPVRPRRQIVYPLEKLGINAPSKAVSKDPMSYALNHTNRKLTLEPKITVNAKIIVVGASSVGISFLETLVFCSHMKFNNLTLISTHGLPGKKLLDTEQRKFLASDHCFNDKDYALMSLCSWVNVVVGRMTGIDRAAKHVVLSTDEIVPYDHLILCTGQQYQVPCPTEADISQHLTNREVPNSSQRRYT---------GKVPCNHFTLNEEEDCFKALIWIRNNSITTEGNIIVYGNTIDTYTTVETLLNLGVSGSRIHLVQPPPASTITCINNYSVESAVADALGAAGVTMYRDAILAQWNDGLH-PDPIYSASFTTPTKPFRLQCSMFFSFCEKNVDYETFKALNDACLVYDSRLVIDTNFHTNDIAIRAAGSLTKFSNRYYSNEWTHSNFSSKEIGFQLAAAMLHLFDPTLEPVTEPPANLDRLIPMYKGAKIQGGILPGSYHYLHIAKPAIPTPLEVQMAQPNYGLELVTGS--AKNGTYFRIHINKYKMVETITCLSREPFPASNYIRLFGQHEQLLNNLCARYDENLITDLYSYFTEPWCLALFHDRFIDLRKELRQILASKEEEDLPSIEQLAHQIEDEEINPTEKPRQYLKRVFEESIYKTLVERSTLDYLHYNRYHLPMYAWPGIV 1237
BLAST of cilia- and flagella-associated protein 61 vs. UniProt/SwissProt
Match: sp|Q8CEL2|CFA61_MOUSE (Cilia- and flagella-associated protein 61 OS=Mus musculus OX=10090 GN=Cfap61 PE=1 SV=2) HSP 1 Score: 728.783 bits (1880), Expect = 0.000e+0 Identity = 383/876 (43.72%), Postives = 563/876 (64.27%), Query Frame = 3
Query: 1041 GESNAIIIQLFAINEAYEMR---------SIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLN--EHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEG-YFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
G+ A IQLF I+E YE R S+DF+ VF LFP +++ LI+VP L PEF L++NFV++ P L H+LY FH+ L+ + IR A D ++ ++ + LS IL+DL Q++ A R G +L +VAE ++IVG+ V+++E DIEYIRSHYNIEDFIYF+HH + EHG + HFA+NPIFR +K FLKE +R K+ +YYPVY KL + HSL + L LVP+RPRRQI+Y ++KL NAP++ + + Q + L H NRKL +EPKVT+N RIVVVGAS+ G+SFLE+L F HLKFNNL L+S +GLP + + D F+ K L +L V+VV G MTAIDR K + ++ ++ YDH+I+ TG+QY +PCPT A + T +E +RY+ VP NL ++ND ++L ++R++ +L E K+I+YG++ ++Y + T+L++G+ G I+FV PP + + +N+ VE AV L AGV + + +AQ+N P+ I + FTT P+RLEC F S+YKK V+Y F+A ND+CLV+D RLVIDT FHTND++IRAAG +TKF RYY+ +W+H+ F+S+ +G +L+ L LFDPTL PV PP + LIP+Y + ++ ILPG +HYL +S+P++ PL+ +QP++GS + TG ++G YFRL++N YK VE ITC K+ +P NY++L+G HE+ LNNL +RF++ LI DL+ +F + W MA +HDRF DLK+E++++L+++ + EE + E + L + +K L F +S KS +++ ++ ++ YN YHLPMYA P ++
Sbjct: 389 GDPIAFCIQLFCIDERYEARQVLISNVSLSLDFMSFVFSLFPGKNFCLISVPHLTPEFVLIQNFVKVVPFNNCTLDHDLYVFHRAGLLRSITIRLAKFLDTAGVEKLVSTLLLSTKILDDLAQYNEAGRDPDGTALQVFVAEVADQIVGIAVIRKEMDIEYIRSHYNIEDFIYFSHHQQEEHGRLNHFALNPIFRHYTKFFLKEILRLGYKSCLYYPVYPQTREGKLQSSYSHSLTSALHYLVPVRPRRQIVYPLEKLGINAPSKEVSKDQVSFALNHTNRKLTLEPKVTVNARIVVVGASSVGISFLETLVFCSHLKFNNLTLISTHGLPGKRLLHNEQRKFLASDHCFNDKDYALMSLCSWVNVVVGRMTAIDRAAKQVVVSKSEIVFYDHLILCTGLQYQVPCPTGADTEQHLTNREVLELSKQRYT---------GTVPSNLFILNDEEDCVRMLCWLRNSSILTEGKVIVYGNTLDAYTTVETLLNIGMKGSGIYFVHPPTESNITCINNNDVESAVEDALSAAGVTVFHDALLAQWNHGQH-PDPIYNACFTTSTKPIRLECSAFFSFYKKNVDYETFKAFNDACLVYDGRLVIDTTFHTNDIAIRAAGSLTKFSNRYYSNEWTHSNFSSKEIGFQLAAAMLSLFDPTLEPVTEPPADLDRLIPMYKGAKIQGGILPGSYHYLHISKPAIPTPLNLQRSQPDFGSDVVTG--NAKKGTYFRLYINNYKLVEAITCFSKEPFPSSNYIRLFGQHEQVLNNLCTRFDDKLIPDLYSYFTEPWCMALFHDRFIDLKKELRQILISKQEEDKPTMEEIAYRLEEEEINLNEKPQKYLQRVFEDSIYKSLLEKSILDYLHYNQYHLPMYAWPGII 1252 HSP 2 Score: 165.236 bits (417), Expect = 8.356e-40 Identity = 103/274 (37.59%), Postives = 158/274 (57.66%), Query Frame = 3
Query: 54 MYARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKL--KECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIF-INTDKGKIPENFGTQFTQIKSI--TDYKNWF---ILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPS 851
++ RRTES D I+ L+ + +FG+ N+I ++EKA L+VT+ + EI+ ++ F DYPN + +W + + KE P PLN+LFMH+F++ E + L EI+ TVF +++IF I + T F Q+ +I +Y F I R + P L+IR A+ ED DDLMPIF LK+IYGE++LAE+++AQ+ +V EV G AVGF+SV T +N+ LL+ F L F GF P + ++I + +++PS
Sbjct: 14 VHCRRTESQDIFCIKNLVRKFTQKLFGRLNIIYLLEKANLAVTVCNDKEEIMAHSIFLDYPN-WNVAKQDNWIPLFRELDKEIP-CTPLNTLFMHFFVAVDEYATGCLKEIIRTVFKAVPELYFIFLIVPTYLSLGSTLITVFDQVGNIPCLNYNEDFAVHICHRHNHYPQLHIRKARVEDHDDLMPIFMHYDNTLKEIYGEYFLAELIEAQDKDHHAVVCEVEGKAVGFMSVCTSVNLPLLHECFDLGPFHGFCTP----HPDDILKPSREPS 281
BLAST of cilia- and flagella-associated protein 61 vs. UniProt/SwissProt
Match: sp|A8IF44|CFA61_CHLRE (Cilia- and flagella-associated protein 61 OS=Chlamydomonas reinhardtii OX=3055 GN=CFAP61 PE=1 SV=1) HSP 1 Score: 242.662 bits (618), Expect = 2.643e-64 Identity = 194/815 (23.80%), Postives = 354/815 (43.44%), Query Frame = 3
Query: 1038 PGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNEHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERIL---QVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHI--HDNYCVAQFNDSDEV-PNWISSVSF---TTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYL------SVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSS 3437
P + + + ++ A+E ++I+FL F + ++ Y ++T+P E L+ R++P PG + P L+ FH+ +LI +F +R D + + ++ M + +I+ A + C ++VG++ + E D+E +++++ + + + + R +HG I + +NPIF + + MR KT++YY + P +Q ++ LE AP R Q+Q + L F R+ A + + ++N++IVVVGAS GL+ +E L P L+FN L LL+P G+ ++ G F+ + L +V ++ + +DR KL+ ++ + Y+ +++A G+ Q++ R++E + ++ L + D F ++ M+ S I++YG++ +Y L + + G G + FV PP + P + ++ EAGV + + +A + V P +S + GP L +L V V+ S F +ND+ LVFD RLV+D F TND +I A G + K RRY H +NSR VG L+ + F+ P ++ + C LPGG++++ ++ RPS T P G + T + G R+ L+ +V ++ L + A L G+H LN+L ++ IK L F + W+ Y++ F +L+E + E+ + S
Sbjct: 389 PADPTLFAVTMLCMDPAFEAQAIEFLTPAFAAYTDKLYCVVTLPHDSREPALMGTMTRVAPNPGSLFPEVLFMFHRHALIPDFAVRLGEPGDLDAVASLVAGMPNADDIVASFSGAAAAGSAAVAL--------CQGELVGLVTVNPEVDLELLQANFGLSNHVDLGYQPREQHGEIDMYTMNPIFVHRHRTLVAATMRLLGKTALYY-------------------------ALPPGQQPPDMLEVLEQVAPRHRTASDKQLQAEFALYVFTRQAAFKRRRSVNSQIVVVGASECGLAVVERLLLDPELQFNYLTLLAPGGI-----------KVGGMACQFTAGVIARLGLEARVMLLDAEVIGLDRGSKLLDLSDGSQIFYNQLVLAAGL---------------------QDQSRYRFAEA--DPEVAGLLVTELELAAD---------FSMNDAMVMNS-ILVYGNAMGAYHSLAVLEAKG-AGEKTRFVAPPGQQ-------PPLVGVLHALAGEAGVALPSPEPRDLAGLSVVQPVGPELHASATLIDPADPGPREELPVDLVVGCEPPSVSRSLFTCLNDASLVFDGRLVVDGAFRTNDPAIYAGGSLAKLSRRYGGTHLEH--YNSRDVGSRLASSLVSFFNAGPDEPQPAATAAAPPPALHRARAV-GCSLPGGNYFVYAGCPAALQRPS--------TAAPEGGYEMKTA---SERGLTRITLDGEGRVHSLMYLGRVAVNAPRLGSLVGLHANYLNSLAPKYQAGDIKCLLSFITEPWSELLYNESFPELRETLLEVALAELS 1104 HSP 2 Score: 58.151 bits (139), Expect = 5.181e-7 Identity = 34/102 (33.33%), Postives = 52/102 (50.98%), Query Frame = 3
Query: 522 REAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDI---------YGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKP 800
R+A +P L IR A+ ED DD++PI + + F L +V Q+++ + LVAE G VGFI +T+D++ L F L A++ F P
Sbjct: 160 RDAVVPPLAIRPARVEDHDDMLPILQRCEVAFPALAKLPEASRPHEPFALTRVVAGQDERNRVLVAEAEGRLVGFIVMTSDVDTGSLAETFDLHAYDNFLPP 261
BLAST of cilia- and flagella-associated protein 61 vs. UniProt/SwissProt
Match: sp|Q23F13|CFA61_TETTS (Cilia- and flagella-associated protein 61 OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=CFAP61 PE=4 SV=1) HSP 1 Score: 238.039 bits (606), Expect = 2.865e-62 Identity = 241/999 (24.12%), Postives = 437/999 (43.74%), Query Frame = 3
Query: 1008 LNDIPNNFEFPGES-NAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISN-FKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNEHSLVTNLQDLVPIRPRRQILYDIQKLE--------GNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNH---PTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTT--------KESQNKPDRRYSEL------MFKKH-MEKIVPDNLMVVNDPF--GAFKLLEFVRHNLMLNESK-----IIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVF------------------------PLNDPVVEEAVYKTLDEA------GVHIH--------------------DNYCV----------------AQFNDSDEVPNWISSVSFTTHGPPLRLECEL-----------------FVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHA----RFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQE--GYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGV---ELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKP 3623
L+ IP E P ++ NAI+I LF I+E +E RS+DF++ F +F +RDY+++T PF VPE TLL+ F++I + H LY +HK L+SN IR++ +D + + + N+ + I +D L T A+ C ++G+ V+ + +++Y SH+ ++D I H + H + H A+NP+F + ++ LKE +R KT +Y+ V + + NE V Q ++ + +D + E + + Q Q + L+ +K+ KV NTRIVVVGAS TG+SF+ESL + F ++ LL+P G+ H P D QL +++ ++L+ L +V+V+ M +D+K K I ++ LPYD+++ G+ TE + + +T ++ +K R +++ +F +H + + ++DP+ FK N+ L K I IYG + + + +++ G+ RIH+V PP +VF P +DP VE+ +++ ++ G ++H DNY A ++D+ + S P+ LE E+ V+ ++ F ++++ LV++ RL++ + F T + I G + +F +RY + ++N R +G++L+K L D + +T + + +P Y I LPG Y + + P T+ + N +++ + Q+ Y + + ++ +T L + +++ V G+ E+ LN L+ RF LI ++ EF + WA+ YH+ F + + I ++ M +S +E + G E + + ++ E S + Q + FI N HLPMY P
Sbjct: 722 LDSIP---EVPIDAQNAIVINLFCIDENFESRSLDFVEYAFSIFGDRDYIILTQPFTVPETTLLQQFIKIPMKKNSTFDHVLYIYHKDCLLSNTLFIRKSKLEDMQYVAPLFSNLINKQQIYDDT----LEAITQTASRKVAFSVFCDQSLIGIYVVSKNVNLDYYISHFCVQDHIILKEHPMTCHTKLIHTALNPLFTKNTRFILKEILRLMNKTCMYFEVQEKTLLPDVFNELVFVRARQFPHFLKRKWDFEHDKEHFERAGDLTEVQDGKRDAFDQEQAPFSLSVITKKMMSSVKVNNNTRIVVVGASDTGISFIESLLSVKDINFTHITLLAPGGIMTMHINLPGD----QLKALSTNYTLEELKNLMLDARVNVLDAKMVELDKKGKKIKLDKNAELPYDYLVNTVGL-----IDTELQNRRLISTGLFSSPYYQQLLDKYGRDRAQIEEGAPPIFGQHPVYGNYVQGVYSIDDPYLYEEFKKTGKKDSNIDLLTRKKRPQSITIYGRTLHTIAFISGMVNRGVHPNRIHYVIPP---KVFETQVQFKNNTERLIYEDKRINDPDPFDDPSVEQKIFEFMESKGIQVHKGYNLHQIDVDEETRICQGVVFRKKADNYEEIIQQIEIKKQQILERDANSENADKGFDDTQSRDGDEENQPITLEQEIEELERNKFDDIEITSRFLVTSGLVDIDKEIFYIIHENGLVYNGRLIVKSNFQTTEKDIFCCGKICEFSQRYKRLSIGRSLRLDKYNGRELGQKLAKCLL---DSLDLGYLTDQIYSLGELPNLYMPIGIGAFLPGDLFYYHIKKNDYARPSKTMEAEDNRQDIVSDNIDQKQQIGHYIKFKFDNNGIIDQVTYLGTEPVSVQSLVSFVGLSEKCLNQLDVRFKNGLIPNISEFLSENWAIGLYHEWFSEFR-HITKMEMLQSENIQQILDEAAKYAQGGGFLDPEFIEKIKAKISPEI-----ISQIQQGTLDFIRENQNHLPMYYVP 1692 HSP 2 Score: 99.7525 bits (247), Expect = 1.270e-19 Identity = 85/304 (27.96%), Postives = 141/304 (46.38%), Query Frame = 3
Query: 45 DFNMYARRTESLDAVEIEKLI-----NSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPN--IAEIDTSSD--WNEIV----KLKECPLANPLNSLFMHYFLS-------KPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIPENFGTQFTQIKSITD-------YKNWFILKR---------------EAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQN----------DQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKP 800
+F + R+++ D E+ K+I +N + ++ PNL+++ EK LSVT+ ++ +I+G A F D+P +ID + W + E P N+L+M +F E E I ++ V+ T + I +G+ E+ G Q QI SI + K+ I+KR A + IR A+++D DDL IFN QS +L +GEF++A+++ QN + K +V +V AVG +S++TDI+ L F LE ++ KP
Sbjct: 32 EFQVLVRKSDLDDVDEVLKIIAQHEREANDL-LYDYPNLLSLFEKNYLSVTILNQQQQIIGAAVFNDFPQGLTGQIDFQHENFWENWIFDAFNFDESICITPFNTLWMTFFFVAKDQYKFSQEEELIICQKVFQNVYATLPQLEGILF-LKRGETMEDNGAQ-AQISSILENIFIEVPVKDRDIIKRVRGIHLNSEVFYSPKHACQEIIEIRMAREQDHDDLAEIFNRQSEVLTAQFGEFFIADLIATQNLTRRGTRKFLNNGKAIVGQVRDKAVGLMSISTDIDYKFLAQCFELETYDNLFKP 332
BLAST of cilia- and flagella-associated protein 61 vs. TrEMBL
Match: V4B959 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_107567 PE=4 SV=1) HSP 1 Score: 1014.6 bits (2622), Expect = 0.000e+0 Identity = 527/1230 (42.85%), Postives = 771/1230 (62.68%), Query Frame = 3
Query: 60 ARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVK--LKECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIPENFGTQFTQ----IKSITDYKNWFILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKP------------------VQTVNEENI---EQLAKKPSND-------SQTSSTEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNASIRS-GLNDIPNNFEF----PGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNEHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
ARRTESLDA I KL + +FG+ +++ IIEKA+L++TL ++ EI+G+A+FYDYPN ID ++W + ++ E ++ N+LF+HYF+++P + EI+ T F ++H+I + G P+ ++ Q I S+ F+ KR ++P L++R A+ ED DDL PIFN QS +LK IYG+F+LAE+++AQ+D+ +CLV E G A GF S+ ++N DLLN F L F G +KP V+T E++I E + PS D ++TS E S + ++ S I F ++ S AS R G F F GE+NA IQLF I+E YEMRS D L F LFP+ D+ +ITVP LVPEF LL FVR++PR L ELY FH+ L+ NF +R AC KD ++ ++ ++ ++L+D +QF ARR + G + A+VAEC +IVGV ++++EEDIEYIRSHYNIEDFIYF HH R +HGH+ HFA+NP+F LSK FLKE +R KT +YYP+Y P+ S +L ++++++ L DLVP+R RRQ+ Y+I L N+P++R+L+ + L H NRKL +EPKVTIN RIVVVGAS G++FLE+L + PHL+FNN+ L+SP+G P L ++ K++ SK + S LR + +V G MT IDR +K + +N +++PYDH+II TG QY +PCPTEA +++ T KE N PDRRY P+NL +VND + + L +++ LM + +KI++YG++ ++Y C+ ++L GI G I V PP +V N+ V+E+ V K L++ G+ I++ + +A++ +D+ I+SVSFT+ PL L C F S YKK V+ +F+A+ND+CLV+D +LV+D+ FHTND+SIR AG +TK++R+YY +WSHA FNS+ +G L+ L+LFDPT+ P P E+ LIP+Y ++ +LPGG++YL V +P LD+PL +YG L TG P ++GYFRLH+N Y +ETITCL K+ N + LYG+HE+ LNNL SRF+E LI D + +F ++W + YHDRF DL++E++ELL+T + E+ +R ++ E + L +Q EL + ++ S AK V+ RL++F++YNYYHLPMYAKP MV
Sbjct: 20 ARRTESLDAPHIIKLAQQTTSELFGRVDVVEIIEKAVLAITLNNEKDEILGHAAFYDYPNTKSID-QAEWVDWIRNNFDEVQKSSAFNTLFLHYFVARPGYANGCAKEIMRTAFTAIPDVHFIILMVPNGTFPDPSLSEIFQPLKRINSVGSEVTAFVCKRHDHVPVLHVRQARVEDNDDLTPIFNRQSDMLKSIYGDFFLAELIEAQDDEMQCLVVEAEGTACGFTSLNKNVNYDLLNECFELAPFHGLRKPHDEDDLVPPATPVPSPITVETRREDSIHSRESKTESPSLDKDETTLKTETSKLETSDKLKTSRQSSAASARGLLLFSLILFDTVVY---SRASERKKGFALSEQRFRFVPTYKGEANAFTIQLFCIDEKYEMRSKDILSKAFSLFPHCDFCIITVPHLVPEFPLLHGFVRVTPRSPSTLSQELYVFHRSGLLKNFNVRTACTKDIHGVENLVKSIHCQSDLLDDFKQFRAARRDEDGKEIQAFVAECSEQIVGVCIVRREEDIEYIRSHYNIEDFIYFNHHRREDHGHLHHFALNPVFSHLSKHFLKEVLRLGHKTCLYYPLYPPYISHELTTKNTMISALNDLVPVRARRQVNYNIDILGENSPSDRVLKQTHPFALCHINRKLTLEPKVTINARIVVVGASDVGVAFLETLAYCPHLRFNNVTLISPHGFPGEIDPSLLQHPMLTKNYPTSKDEEIWSFLRTWISIVYGKMTGIDRTRKQVKVNSSFIVPYDHLIICTGQQYQVPCPTEASLEHGVTNKELPNSPDRRYKGSQ---------PNNLYLVNDYYDSLTLQHAIQNKLMPSNNKILLYGNNIDTYTCIQSLLQYGITGDNILLVLPPQAYDVTCFNNKVIEDTVRKALNDNGIKIYEGFLLAEWTLNDDTD--ITSVSFTSDDEPLTLSCHAFFSLYKKAVDMDSFKAINDACLVYDGKLVVDSLFHTNDVSIRGAGTLTKYQRKYYGNKWSHANFNSKEIGIALATEILKLFDPTVEPEAYPREEQFNLIPLYRAPKIQVTMLPGGYNYLHVKKPGLDVPLEIQMANEDYGKELVTGEPDSEKGYFRLHVNLYNSIETITCLAKQEVTCSNLLCLYGLHEKYLNNLVSRFDEGLITDFYSYFKESWCVGLYHDRFSDLRDELRELLITSPEEGKETLEDQIRQLIDEEMSLNSKQHDELNEIYKLSGAKQAVETRLLNFLSYNYYHLPMYAKPGMV 1234
BLAST of cilia- and flagella-associated protein 61 vs. TrEMBL
Match: R7TM94 (DUF4821 domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_159925 PE=4 SV=1) HSP 1 Score: 1008.82 bits (2607), Expect = 0.000e+0 Identity = 537/1229 (43.69%), Postives = 767/1229 (62.41%), Query Frame = 3
Query: 60 ARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVK----LKECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIPEN-FGTQFTQIKSITDYKN-----WFILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFK--------------KPVQTVNEENIEQLAKKPSNDSQTSSTEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNASIRSGLN----DIPNNFEF----PGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQ---KLLNEHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKI-KNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDE--VPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
ARRTESLDA I KL+ S++ +FG+ N++N+IEKA+L+VTL++ +++G+A+F+DYPN ++D ++W + + LK+C + LNSLFMHYF++K E EIV T+FN ++HY F+ G PE+ F Q+ N F+ R ++P L++R A+ ED DDL+PIFN QS +LK YGE++LAE+++AQ++ KC+VAEV G A+GF+S+ D+NIDLLN F L F G + PV +E ++ S S S + P + + + + S S + LN D+ N +F G S+A IQLF I+E++EMRS DF+ F+LF + ++ +ITVP LVPEF LL+ FVR++PR ELY F + LI +F +R AC KD E ++ ++ + +L DL+Q++ ARR D G + A+VAE ++IVGV +++ EEDIEYIRSHYNIEDF+YF HH RSEHGH+ H+A+NP+FR SK FLKE +R KT +YYP+Y + + + L +H+LV+ L D+VP+R RRQI+ I+ L GNAP+ERIL+ QE Y L H NRKL +EPKVTIN RIVVVGAS G++ +E+ PHL+FNNL L+S +GLP P D L + +M +S+++ +R V+VV G MT+IDRKKK + +N ++PYDH+++ATG+QY I PTEA + + + N PDRR+ P+N VVND + A L +V N++ + ++IYG + ++Y C+ +++S+G+ RI V+P E N+ VVEEA+ L+ AGV + + Y +AQ+ND + I+S SFT+ LR EC F S+YK +V+Y +F+A+ND+CLVFD RLVID FHTND+ IR AGP+TKF+R Y+ ++W+HA FNS+ VG +L+ L LFDPTL P PP + + LIP+Y + LPGG HYL V++P L PL L Q +YG + TG P + YFRLH+NQ+ +ETITCL KK P N + L+G+HER LNN+ SR E LIKDL+ +F++ W MA +HDRF D ++EI+ELL+TR + + EE VR + E + L RK L+D++++S AK V+ RL+SF++YNYYHL MYAKP MV
Sbjct: 16 ARRTESLDAPGILKLVQSSTEALFGRVNVVNLIEKAVLAVTLSNDEDDLLGHAAFFDYPNQTDVD-QAEWEKWITENYGLKKC---DALNSLFMHYFVAKQEYSHGCAREIVRTMFNAVPDLHYCFLIVPPGVFPEHAISDIFKQVDKAGSIPNQQSGSLFVCHRHDHVPVLHVRTARVEDHDDLVPIFNRQSDLLKSTYGEYFLAELIEAQDENMKCIVAEVEGTAIGFMSINKDVNIDLLNQCFELGPFHGLRVPHEDDELEPTPTPNPVSEGQKEATSATSRASSKISLKGSAKVEEPPAIQGKLSDGNASLLSEHSEKGSRKSSASQAREPVEELKLNQVFIDVKTNLQFVPVYKGVSSAFAIQLFCIDESFEMRSCDFMFKAFELFESCNFGIITVPHLVPEFPLLQQFVRMTPRVPSTFSQELYVFSRAGLIRSFNVRLACTKDFEGVESLVKTLDQKEILLADLQQYNQARRDDDGTQIQAFVAETRDQIVGVAIIRAEEDIEYIRSHYNIEDFVYFNHHRRSEHGHLHHYALNPVFRHYSKHFLKEVLRLGHKTCLYYPLYPGYINHLIFQTLGKHTLVSALSDMVPVRARRQIVQPIEDLGGNAPSERILKQQEMYALNHINRKLTLEPKVTINARIVVVGASDVGVALMETFAHCPHLRFNNLVLISRHGLPGELPPDPLRDSMMASSHCYSQEEYAQMGIRAWVNVVYGNMTSIDRKKKHVVVNSNTIVPYDHLVLATGVQYQIAAPTEADPDQQYADVSDLPNSPDRRWL---------AACPENAFVVNDQYEAAVALYWVETNILHTDGSVLIYGSTMDTYSCVQSLISLGLPAKRIVIVEPLQTSETSCFNNRVVEEAIMLELNNAGVKVVNGYLLAQWNDGKDGNCVTRINSASFTSPLGSLREECCAFFSFYKPMVDYLSFKAINDACLVFDGRLVIDANFHTNDVCIRGAGPLTKFQRNYHADKWTHANFNSKDVGVQLASAMLTLFDPTLEPEPEPPKDLLKLIPMYRSPKICKATLPGGFHYLHVAKPQLTSPLEILMQQNDYGQEIITGTPGGEIEYFRLHINQFNTIETITCLSKKPLPTNNLICLFGLHERFLNNIVSRHQEGLIKDLYSYFNEKWCMAIFHDRFPDFRDEIRELLITRPNDDVPALEEQVRKYIDEDLNLAPSVRKHLLDDYKDSGAKRAVETRLLSFLSYNYYHLTMYAKPGMV 1231
BLAST of cilia- and flagella-associated protein 61 vs. TrEMBL
Match: A7SG85 (Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g245069 PE=4 SV=1) HSP 1 Score: 977.237 bits (2525), Expect = 0.000e+0 Identity = 525/1208 (43.46%), Postives = 747/1208 (61.84%), Query Frame = 3
Query: 60 ARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLK-ECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIPENF--GTQFTQIKSITDYKNWF---------ILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPSNDSQTSSTEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNASIRSGLNDIPNNFEFPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNEHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXX--XXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQE---GYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
ARRTESLDA +I KL+ + + +FG+ N++NIIEK+ L+VTL + ++V +A+F+DYPNI +D +S W+ +K K +C A PLNSLFM+YF++KP+ +EI+ TVFN +HYIF+ +P + G T++ YK F + R + P L+IR A+ ED DDLMPIFN Q+ +L +YG F+LAE+++AQ+ + KCLVA+V G AVGF+S+ + + +LN F LE F +K +I + P N+S P ++H+ + + + R P+ G +A IQLF I+E YEMRSIDFL F FP+RDY ++T+P LV EF LL+ F+R++P+ L ELY +H+ LI +F +R D + I+ +I +K S IL D+EQ++ ARR G L +VAEC+ ++VG V+++EEDIEYIRSHY+IEDF+YF HH R EH H+ H +NP+F++ SK FLKE +R + K+ +YYPV+ +AS + HS+VT+L DLVPI RRQI+Y +++L GNAP+ERILQ +E + L H NRKL +EPKV IN RIVVVGAS G+SFLE+ F PHL+FNNL L+SP GLP D+L+ + + +LR ++VVKG MTAIDR K++ ++G + +PYD+++I TG Q+ +P PT A I TT E Y ++ PDN+ VN K++++V + + ++ K ++YG + E++ + +LS GI R+ V+PP N+ +EEA + L +GV +H Y +A++ND N +S +FT+ PLR++C+ F + +K V++ AF+A+NDSCLVFD RLV+D F TND IRAAGP+TK++RRY+ E WSHA FNSR VG+EL++ L LFDPTL EE L+P+Y + S +LPGG+HYL V +P L+IPL +L QP YG L TG E GYFRLH+NQY+ VETITC KK+ N LYG+HER LNNL RF+E LI+D + FF ++W +A +HDRF D +EEI+ELL+ + S S EE VR M+ E + L+++QR+ L D + +S AK ++QRL+SF++YN YHLPMYAKP MV
Sbjct: 12 ARRTESLDAPDILKLVTATTDKLFGRVNVVNIIEKSNLAVTLVNSANKVVAHAAFFDYPNITGVDQAS-WDTWLKSKYDCDKATPLNSLFMNYFVAKPDFAYGCAVEIIRTVFNAVPFLHYIFL-----AVPRSVETGAALTEVFKPMSYKESFTGKLNCEVQVCHRHEHCPKLHIRPARVEDHDDLMPIFNRQNDVLTSMYGNFFLAELIEAQDSENKCLVADVNGTAVGFMSICSQMEARILNRCFDLEPFNRLQKTA------DIGEEPDDPINES---------PEIIHKLSE---------------EHLVQRCPTPPH---------------GPCSAFCIQLFCIDEKYEMRSIDFLPAAFAQFPDRDYCVLTMPHLVSEFPLLQAFIRVTPKRHSTLSQELYVYHRWGLIESFNVRPCISSDSDAIRKVIKKLKASDKILMDVEQYNRARRDPDGTELQVFVAECIGQVVGAAVLRREEDIEYIRSHYSIEDFVYFNHHQREEHAHLHHLILNPVFQQYSKHFLKEVLRLAHKSCLYYPVFPVYASGSVTKNHSVVTSLNDLVPIAARRQIIYPVKELGGNAPSERILQEKEAFALNHLNRKLTLEPKVVINARIVVVGASDVGISFLETFVFCPHLRFNNLTLVSPQGLPGQTAPDKLVNSCLPSSMCYDDDIYANMSLRTWINVVKGSMTAIDRTNKILKVSGGFGVPYDYLVICTGQQFQVPAPTGADISTLVTTSEVPRPRTAVYRGML---------PDNVFTVNSHGDCAKVVKWVNNYFLNSQGKALVYGCTLEAFTFVQGLLSAGIPADRLVMVQPPPPVPSC-FNNIDIEEATDQALQASGVEVHVGYVLAEWNDGKYDSN-LSCATFTSENKPLRVDCQAFFCFQEKRVDFQAFKAINDSCLVFDGRLVVDANFRTNDPFIRAAGPLTKYQRRYHAESWSHANFNSREVGDELARSMLALFDPTLEGFMPGPVSEEEDKLVPLYKKPKMVSAVLPGGYHYLHVGKPGLNIPLDSLMVQPEYGRELLTGNAKEAESGPGYFRLHVNQYRSVETITCYSKKSLDTTNLKCLYGIHERYLNNLLQRFDEGLIQDFYSFFQESWCLAVFHDRFNDFREEIRELLVNKPSDDVLSLEEKVRKMIDEDLVLSKDQRRNLSDNYVSSPAKKAIEQRLLSFLSYNGYHLPMYAKPGMV 1157
BLAST of cilia- and flagella-associated protein 61 vs. TrEMBL
Match: A0A210QNZ2 (Uncharacterized protein C20orf26 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT09429 PE=4 SV=1) HSP 1 Score: 904.434 bits (2336), Expect = 0.000e+0 Identity = 435/877 (49.60%), Postives = 600/877 (68.42%), Query Frame = 3
Query: 1008 LNDIPNNF--EFPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNEHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
L+ +P F + GE NA IQLF I+E +EMRS DFL F LFP D+ +ITVP LVPEF LL+ FVR++PR L ELY FH+ L+ +F +R AC KD ++ ++ + L N++ DL+Q++ ARR + G+ + A+VAEC +IVG V+++EEDIEYIRSHYNIEDFIYF HH R EHGH+ HFA+NPIF LSK F+KE +R+ KT +YYP+Y P+ ++++ +HSLV L D+VP+R RRQI+Y ++KL NAP+ER+L ++ Y L H NRKL MEPKVTIN RIVV+GAS G++FLE+L +SPHL+F+NL L+SP+GLP DE+ +Q++G F +++ + ++LR V+VV G MTAIDRKKK + + ++PYDH+I+ TG QY IP PTEA I+ T + N PD RY K P NL ++ND + A L ++ ++L+ + K++IYG + ++YCC+ ++L+MG+ G RI V+P + N+P ++ + K++ EAGV ++ Y +AQ+ND I+S SFT++ PL LEC F +YYK V+ +FRA+ND+CLV+D +LVID FHTND++IR AG +TK++R+Y+ EQW+HA FNS+ VG L+ LRLFDPT+ P PP E + LIPIY + ++ ILPGG+HYL V++P LD PLS QP+YG TG GYFRLH+NQY +ETITCL K+ P N+ LYG+HER LNNL SRFNE L+KD +F + W +A YHDRF D ++E++ELL+T P S EE VR ++ E V + Q+ EL+D +RNS AK V+ RL+SFI+YNYYHLPMYAKP MV
Sbjct: 421 LSSLPKRFVPSYKGEVNAFSIQLFCIDERFEMRSSDFLTKAFSLFPQFDFSVITVPHLVPEFPLLQGFVRVTPRCPSTLSQELYVFHRSGLMKDFNVRPACTKDTAGVEKLVKTVSLQDNLMADLKQYNQARRDEDGMEIQAFVAECQGQIVGTAVIRKEEDIEYIRSHYNIEDFIYFNHHRREEHGHLHHFALNPIFSHLSKHFIKEILRQGHKTCLYYPLYPPYTDKQIVEKHSLVCCLNDMVPVRSRRQIIYPVEKLGVNAPSERVLADRDAYALNHINRKLVMEPKVTINARIVVIGASNVGIAFLETLAYSPHLRFHNLTLISPHGLPGEMAPDEVRDQMLGNSFCYNQNEFSKTSLRTWVNVVYGKMTAIDRKKKFVVVENSSMVPYDHLILCTGEQYQIPAPTEADIEGGATNADLPNSPDMRYM---------KAQPKNLFLINDEYDAAVALYWIENSLLKSSRKVVIYGGTLDAYCCVQSLLAMGVTGDRISLVEPSAAYQTTCFNNPTLDATILKSVKEAGVQVYSGYYLAQWNDGIGEIGEITSASFTSNKEPLILECGAFFAYYKASVDTDSFRAINDACLVYDGKLVIDAAFHTNDVAIRGAGTLTKYQRKYHAEQWTHANFNSKEVGIHLATEMLRLFDPTMEPQSAPPEEALNLIPIYRNPKIQGGILPGGYHYLHVAKPGLDTPLSNQMAQPDYGKEYITGTVDGDPGYFRLHINQYNTIETITCLSKQPIPSSNFNCLYGLHERGLNNLMSRFNEGLVKDFISYFMEKWCLAVYHDRFADFRDEVRELLITSPGPGQESVEERVRQVVDEDVAMNESQKGELLDIYRNSGAKRAVETRLLSFISYNYYHLPMYAKPGMV 1288 HSP 2 Score: 205.297 bits (521), Expect = 1.042e-49 Identity = 106/254 (41.73%), Postives = 159/254 (62.60%), Query Frame = 3
Query: 60 ARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLK-ECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIPEN----FGTQFTQIKSITD--YKNWFILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKP 800
ARRTESLDA I KL+ N+ +FG+ N++N+IEKA+L+VTL + +I+G+A+F+DYPNI E+D +S W +K + LN+LFMHYF+ K + EI+ T FN ++H++++ PE+ Q + + ++D F+ R ++P L++R A ED DDL PIF QS +L YG+F+LAE+V+AQ++ +CLVAEV G A+GF+S++ D+N LLN F L F G +KP
Sbjct: 17 ARRTESLDAPHIIKLVKENTDALFGRVNIVNLIEKAVLAVTLCNDKEDILGHAAFFDYPNIPEVDQAS-WESWIKNSYGNEKSTALNTLFMHYFVGKSDYAHGCCREIIRTAFNAVPDLHFLYLFVPMKAYPESALDEVFKQVDKTEGVSDGVSGALFVCHRHDHVPVLHVRKATVEDHDDLTPIFTRQSDMLNMTYGDFFLAELVEAQDEHMQCLVAEVEGTAIGFMSISDDVNAPLLNECFELGPFHGLRKP 269
BLAST of cilia- and flagella-associated protein 61 vs. TrEMBL
Match: A0A151NDD8 (Cilia-and flagella-associated protein 61 OS=Alligator mississippiensis OX=8496 GN=CFAP61 PE=4 SV=1) HSP 1 Score: 903.664 bits (2334), Expect = 0.000e+0 Identity = 501/1246 (40.21%), Postives = 747/1246 (59.95%), Query Frame = 3
Query: 60 ARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKL----KECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYI--FINTDKGKIPENFGTQFTQIKSITDYK-----NWFILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKP-----VQTVNEENIEQLAKKPSNDSQTSST---EHSVPVVVHXXXXXXXXXXX----XXXXXXXFHNALFRFPSNASIRSGLNDIPNNFEFP------------------------------GESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLN--EHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
ARRTES D I L++ ++ FG+ N++ ++EKA L+VTL+++ +++ +A+F+DYPN +D +DW + +C PLN+LFMH+F++K E EI+ TVFN +H+I FI + + ++ T F ++ S+ D F+ R Y P LYIR A+ ED DDLMPIF S L++ YGE++LAEM++AQ++ +V E G AVGF+SV +NI LL+ F L F G KP ++ E +IE K S SQ + + + S + H+ +I+ +++ + + +N S + G N I +N E P G +A IQLF I+E +E RS+DFL +F+LFP++D+ +ITVP LVPEF L++NFVR+ P L ELY FH+ L+ +F +R+A D ++ +I + L+++IL+DL F LARR G + A+VAE ++IVGV V++ E DIEYIRSHYNIEDFIYF HH + EHGH+ HFA+NPIF +K FLKE +R + K+ +YYP+Y K N HSL + L +VP+RPRRQI+Y ++KL NAP++++ + Q Y L H NRKL +EPKVT+N RIVVVGAS G+SFLE+L F PHLKFNNL L+S +GLP + D + + F+ K L +L V+VV G MT IDR K + ++ +PYDH+++ TG QY +PCPT A I T +E +RY+ VP NL +++D K ++++ N + +I+YG++ ++Y + T+LS+GI G RIH ++PP+ V LN+ +E AV + L A V ++ + +AQ+N+ P+ I+ SFTT+ P +L+C F+++ K V+Y F+A+N++CLV+D RLVIDT FHTND++IRAAGP+TKF YY +W+H+ F+S+ +G + + L LFDPTL PV PP + LIP+Y ++ +LPGG++YL +S+P + L QPNYG + TG + YFR+H+NQY VETITC KK +P+ NY+ L+G HER LNNL SR+ E LI DL+ +F ++W++A YHDRF DLK+E++++L ++ S E+ ++ L+ + +K L F+ S + V++ ++S++ YN+YHLPMYA P +V
Sbjct: 43 ARRTESNDIPGIVSLVSYSTEIYFGRINVVYLLEKANLAVTLSNEKNKVLAHAAFFDYPNWNVVD-QADWEPFLHQNYSNSKC---TPLNTLFMHFFVAKEEYAVGCCQEIIRTVFNAVPELHFILLFIPSQE-ELGSGLATIFEEMVSVPDSALDMDFTLFVCHRHQYGPLLYIRKARVEDHDDLMPIFMRHSDTLRETYGEYFLAEMIEAQDEDNHAVVCEDNGAAVGFMSVCAQVNIQLLHECFDLATFHGLCKPHPDDVLKLPQEPSIETDKDKSSQTSQRAESVFSQSSECISAHDMDIQIDAKTEDVPPQALDTVATPSPIGSVQTNVSEKDGTN-IVSNAELPLGDVTGTDFKTTGIPTLETDEEDAFHPVYRGAVSAFCIQLFCIDEKHEARSMDFLHFIFNLFPDKDFCIITVPHLVPEFLLIQNFVRVVPFRNSTLDQELYVFHRAGLLKSFNVRRATTSDLPAVEILIKTLDLNKSILDDLRIFTLARRDPDGAPVQAFVAEVSDQIVGVSVVRNEMDIEYIRSHYNIEDFIYFNHHQKEEHGHLYHFALNPIFHHYTKYFLKEILRLAYKSCLYYPIYPQSEEGKFQNPYAHSLTSALHYMVPVRPRRQIVYPLEKLGINAPSKQVSKDQLSYALNHINRKLTLEPKVTVNARIVVVGASNVGISFLETLIFCPHLKFNNLTLISTHGLPGKNLPDLKYRRFLINSHCFNDKDYALMSLCSWVNVVVGKMTGIDRAAKHVVVSKGKKVPYDHLVLCTGQQYQVPCPTGADISKLLTNREVTKSCKQRYT---------GKVPTNLFILHDDQDCLKAAQWLKENFINLGGNVIVYGNTIDTYTTVETLLSLGINGSRIHLIQPPLSSNVTCLNNNAIERAVKEALSMADVSVYYDSILAQWNEGSH-PDPITCASFTTNTKPFKLQCSAFLNFSHKGVDYETFKAINEACLVYDGRLVIDTNFHTNDITIRAAGPLTKFSNIYYTNEWTHSNFSSKEIGFQFAASILNLFDPTLEPVSEPPDDMDRLIPMYKGCKIQGGVLPGGYNYLYISKPGIPTRLDVQITQPNYGMEIITG-EAIRGNYFRIHINQYGMVETITCFSKKPFPVSNYICLFGQHERVLNNLCSRWKEGLISDLYSYFSESWSLAIYHDRFIDLKKELRQILTSKQGDGLPSLEQLACEIVDGEFHLSEKPKKYLKRFFQQSIYRKLVEESILSYLNYNHYHLPMYAWPGIV 1271
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Cavefish
Match: si:zfos-223e1.2 (cilia and flagella associated protein 61 [Source:NCBI gene;Acc:103034939]) HSP 1 Score: 825.469 bits (2131), Expect = 0.000e+0 Identity = 462/1211 (38.15%), Postives = 714/1211 (58.96%), Query Frame = 3
Query: 63 RRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPLA-NPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIPE-NFGTQFTQIKSITDYKNW--FILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPSNDSQTS-STEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNAS----IRSGLNDI--PNNFEFPGES-NAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNE--HSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPD-RRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEG-YFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFE----ETVRNMMVEGVELTREQRKELMDE-FRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
RRTES DA +I +L++ + +FG+ N+I ++EKA L+VTL++ +I+ +A+F D+P I ++ + W E +++ A PLN+LF+H F+++ + EI+ TVF+ + + YI + T E F + +T+ F+ R + P L++R A+ ED+DD+ + Q+ YG ++LA++++AQ++ V E G AVGF+SV++++N+ LLN F L F+G K +N + ++P D T +TEH +++ + + E+ + R S IR+ D N P +S NA IQLFAI++ +EMRS+DFL VF +FP RD+ +I+VP L PEF LL+ F+R +PRP LP ELY FH+ L+ + ++R D +Q ++ N+ L + +++DL+ F ARR G + A+V E +IVG+++++ E+DIEYIR++YNIE+F+YF+H+ EHG + HFA++P F+ +K LKE +R + K+ +YY VY + SQ+ N L L+ +VP++PRRQI+Y +++L NAP+ I + Q Y L H NRKL +EPKVT+NTRIVVVGAS TG++FLESL F PHL+FNNL L+S +GLPD TD + +S++ L +L V VV G MTAIDR K + ++ ++PYDH+++ TG QY IPCPT I + +T + +KP R+Y++ VP N +ND + ++ N + + ++YG S + Y C+ T+L +G+ G RIH V P D+ + V++AV L + VH+H +AQ ND P +++VSFTT GPPLRLEC +F ++ K V++ AF+A+ND+CLVFD RLVIDT FHTND +IRAAGP+TK+ RRYY +QWSH FNS+ VG+EL V L FDPTL P E LIPI+ ++ LPGG+ YL V++PS I +T + G + TG + G YF L N + +E TCL + P+ NY+ LYG H+ LN+L RF+++LI DL+ +F +TW MA +HDRF D ++E+++ +M ++ + + M+V G + E+ + +++ F+NS + + ++ ++ YN YHLPMYA+ ++
Sbjct: 17 RRTESSDAEQICELLSPTAAAVFGRVNVIYLLEKANLAVTLSTAKNQILAHAAFLDHP-IGDLVDQASWEEFLQIHYNGAAFTPLNTLFLHLFVAQSSFAAESAKEIIRTVFSAITELEYICLVTPYNSCLEPALDGIFEPMHCVTEGLQCAAFVCNRHNHCPRLHVRKARVEDLDDITTLLVEQTKAQASSYGPYFLADLIEAQDETNHVAVCENEGIAVGFMSVSSEVNLTLLNQCFELSPFDGLLK----INPADQTDETEEPQQDQPTEENTEHHSEIIL-TQESNEVPAVEGPEEGSECGAGISRVSCGTSETEPIRAHTKDCTGSNVGSEPAQSPNAFCIQLFAIDKRFEMRSVDFLPYVFKVFPERDFCIISVPKLDPEFPLLQTFLRAAPRPFSNLPQELYIFHRTGLLKSLQVRLPVCDDTVAVQRLVENLSLDKALMDDLDMFLKARRDPDGTPIQAFVVEIEEQIVGIVLIRNEQDIEYIRANYNIENFVYFSHYQLEEHGQLCHFALHPNFQHYTKHILKEVLRLAHKSCLYYLVYPTYCSQQENNAFVSYLTAALKCMVPVQPRRQIIYPLEELGINAPSTLITKQQVPYALNHINRKLTLEPKVTVNTRIVVVGASDTGIAFLESLVFCPHLQFNNLTLISTHGLPDCQGTDGTT--FLTTSHCYSERDYALLSLSSWVSVVTGKMTAIDRTAKHVQVSEGRVVPYDHLVLCTGQQYQIPCPTGIDISKWSSTSQEPDKPRCRKYTDH---------VPSNFFTLNDQHDCTQAYNWLLENFIEQDGNAVVYGDSIDMYSCVETLLCLGVRGSRIHVVHTPADKPQSSFKNSAVDQAVRSALQKKEVHVHHGCLLAQLNDGQH-PEPLTAVSFTTDGPPLRLECAVFFNFSCKGVDFDAFKAINDACLVFDGRLVIDTAFHTNDCAIRAAGPLTKYSRRYYADQWSHTDFNSKEVGQELVSVLLPFFDPTLETPNNPAPAEDRLIPIHTQPKIRGGRLPGGYSYLHVAKPS--IYTNTAPSADRSGREMVTG--RVETGNYFHLQFNTHGLLEAFTCLSHRTLPVSNYLCLYGKHQLLLNHLYMRFDQDLIHDLYSYFRETWCMAIFHDRFADFEQEVRQ-IMESTTKVQVDLDLVSIPKLAEMIVYGTLVAAEEPRLYLNQMFKNSEGPDALKRSVLDYLKYNRYHLPMYAQARLL 1204
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Cavefish
Match: si:zfos-223e1.2 (cilia and flagella associated protein 61 [Source:NCBI gene;Acc:103034939]) HSP 1 Score: 755.747 bits (1950), Expect = 0.000e+0 Identity = 424/1102 (38.48%), Postives = 645/1102 (58.53%), Query Frame = 3
Query: 387 TVFNTASNIHYIFINTDKGKIPE-NFGTQFTQIKSITDYKNW--FILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPSNDSQTS-STEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNAS----IRSGLNDI--PNNFEFPGES-NAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNE--HSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPD-RRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEG-YFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFE----ETVRNMMVEGVELTREQRKELMDE-FRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
TVF+ + + YI + T E F + +T+ F+ R + P L++R A+ ED+DD+ + Q+ YG ++LA++++AQ++ V E G AVGF+SV++++N+ LLN F L F+G K +N + ++P D T +TEH +++ + + E+ + R S IR+ D N P +S NA IQLFAI++ +EMRS+DFL VF +FP RD+ +I+VP L PEF LL+ F+R +PRP LP ELY FH+ L+ + ++R D +Q ++ N+ L + +++DL+ F ARR G + A+V E +IVG+++++ E+DIEYIR++YNIE+F+YF+H+ EHG + HFA++P F+ +K LKE +R + K+ +YY VY + SQ+ N L L+ +VP++PRRQI+Y +++L NAP+ I + Q Y L H NRKL +EPKVT+NTRIVVVGAS TG++FLESL F PHL+FNNL L+S +GLPD TD + +S++ L +L V VV G MTAIDR K + ++ ++PYDH+++ TG QY IPCPT I + +T + +KP R+Y++ VP N +ND + ++ N + + ++YG S + Y C+ T+L +G+ G RIH V P D+ + V++AV L + VH+H +AQ ND P +++VSFTT GPPLRLEC +F ++ K V++ AF+A+ND+CLVFD RLVIDT FHTND +IRAAGP+TK+ RRYY +QWSH FNS+ VG+EL V L FDPTL P E LIPI+ ++ LPGG+ YL V++PS I +T + G + TG + G YF L N + +E TCL + P+ NY+ LYG H+ LN+L RF+++LI DL+ +F +TW MA +HDRF D ++E+++ +M ++ + + M+V G + E+ + +++ F+NS + + ++ ++ YN YHLPMYA+ ++
Sbjct: 49 TVFSAITELEYICLVTPYNSCLEPALDGIFEPMHCVTEGLQCAAFVCNRHNHCPRLHVRKARVEDLDDITTLLVEQTKAQASSYGPYFLADLIEAQDETNHVAVCENEGIAVGFMSVSSEVNLTLLNQCFELSPFDGLLK----INPADQTDETEEPQQDQPTEENTEHHSEIIL-TQESNEVPAVEGPEEGSECGAGISRVSCGTSETEPIRAHTKDCTGSNVGSEPAQSPNAFCIQLFAIDKRFEMRSVDFLPYVFKVFPERDFCIISVPKLDPEFPLLQTFLRAAPRPFSNLPQELYIFHRTGLLKSLQVRLPVCDDTVAVQRLVENLSLDKALMDDLDMFLKARRDPDGTPIQAFVVEIEEQIVGIVLIRNEQDIEYIRANYNIENFVYFSHYQLEEHGQLCHFALHPNFQHYTKHILKEVLRLAHKSCLYYLVYPTYCSQQENNAFVSYLTAALKCMVPVQPRRQIIYPLEELGINAPSTLITKQQVPYALNHINRKLTLEPKVTVNTRIVVVGASDTGIAFLESLVFCPHLQFNNLTLISTHGLPDCQGTDGTT--FLTTSHCYSERDYALLSLSSWVSVVTGKMTAIDRTAKHVQVSEGRVVPYDHLVLCTGQQYQIPCPTGIDISKWSSTSQEPDKPRCRKYTDH---------VPSNFFTLNDQHDCTQAYNWLLENFIEQDGNAVVYGDSIDMYSCVETLLCLGVRGSRIHVVHTPADKPQSSFKNSAVDQAVRSALQKKEVHVHHGCLLAQLNDGQH-PEPLTAVSFTTDGPPLRLECAVFFNFSCKGVDFDAFKAINDACLVFDGRLVIDTAFHTNDCAIRAAGPLTKYSRRYYADQWSHTDFNSKEVGQELVSVLLPFFDPTLETPNNPAPAEDRLIPIHTQPKIRGGRLPGGYSYLHVAKPS--IYTNTAPSADRSGREMVTG--RVETGNYFHLQFNTHGLLEAFTCLSHRTLPVSNYLCLYGKHQLLLNHLYMRFDQDLIHDLYSYFRETWCMAIFHDRFADFEQEVRQ-IMESTTKVQVDLDLVSIPKLAEMIVYGTLVAAEEPRLYLNQMFKNSEGPDALKRSVLDYLKYNRYHLPMYAQARLL 1128
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006807.1 (pep scaffold:Pmarinus_7.0:GL482520:855:11431:1 gene:ENSPMAG00000006133.1 transcript:ENSPMAT00000006807.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 656.751 bits (1693), Expect = 0.000e+0 Identity = 345/786 (43.89%), Postives = 480/786 (61.07%), Query Frame = 3
Query: 1290 IRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNE--HSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXX--XXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEG-YFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
+R A D + ++ ++ + + +L D QF+ ARR G + YVAE + KIVGV V++ EEDIEYIRSHYNIEDFIY++HH R +H H+ HF +NP +K FLKE +R S TS+YYPVY P S+K E H+L + L LVP+RPR QI Y + +L N+P++R+L Q+ Y L HFNRKL +EPKVT+N RIVVVGAS TG+SFLE+L F PHL+FNNL L+S +GLP P + E + +S L L +L +V VV G + AI+R K + + G + YDH+I+ TG QY +PCPTEA + T E N PDRRYS VP NL +ND LE++R N + + I+YG S ++Y + T+L +G+ G RIH +PP V N+ VE A+ L +AGV +H + +A +N++ + + I+S SFTT P LEC F ++Y+K V+Y AFRA NDSCLVFD RLVID F T+D ++RAAG +TK+ RRYY + +HA +NS+ VG L+ L L DPTL L+P + ++ ILP G+HYL + +P + IPL +P+YG L TG P ++G YFRLH+ ++ VET+TCL K PI NYV LYG HE+ LN L SRF+E LI DL+ +F W MA +HDRF+DL+ E+++L+ T + S E ++ + L + L ++F+ K V+ RLIS++ YN+YHLPMY +P ++
Sbjct: 5 VRAARSNDSDAVKSLVETLDQHKLLLADFNQFNQARRDPNGTQIRVYVAEMLEKIVGVAVVRAEEDIEYIRSHYNIEDFIYYSHHRRDQHAHLCHFVLNPASYLYTKHFLKEVLRLSHCTSLYYPVY-PGYSKKSWTEKHHTLSSVLHCLVPVRPRSQISYPLHELGENSPSQRVLMEQDKYALNHFNRKLTLEPKVTVNARIVVVGASDTGISFLETLAFCPHLRFNNLTLISTHGLPGELPPCPIREGFLASSHCYSTNDLALLSLHSRVSVVVGKVAAINRSAKHVVVTGGGHVSYDHLILCTGQQYEVPCPTEADLSKLLTNAEVPNSPDRRYS---------GPVPTNLFTLNDQDDCQHALEWLRRNFLGGQGNAIVYGSSLDAYTTVQTLLKLGVAGSRIHLAEPPHGYTVCCFNNFAVESAIRGALLQAGVKVHSSCLLAHWNENAQQSDLITSASFTTDTKPFSLECSAFFAFYRKGVDYEAFRAANDSCLVFDGRLVIDASFCTSDGAVRAAGTLTKYARRYYADHAAHAGYNSKEVGFHLAAGMLPLLDPTLEPPSSDDLSDSLNRLVPTFTAPNIQGGILPRGYHYLHIVKPGVVIPLEAQMARPDYGRELVTGRP--EDGDYFRLHVGRHGTVETLTCLSAKPLPISNYVHLYGQHEQLLNTLLSRFDEGLIPDLYSYFRQPWCMAIFHDRFQDLQRELRQLVSTAQAESVPSMLELATQLVQGDLSLLDGGPQSLHEQFKKLGYKKAVETRLISYLQYNHYHLPMYFRPGII 778
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000113.1 (pep scaffold:Pmarinus_7.0:GL477060:118666:121010:1 gene:ENSPMAG00000000100.1 transcript:ENSPMAT00000000113.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 120.553 bits (301), Expect = 3.931e-31 Identity = 62/177 (35.03%), Postives = 105/177 (59.32%), Query Frame = 3
Query: 51 NMYARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFI----NTDKGKIPENFGTQFTQIKSITD-YKNWFILKREAYMPTLYIRAAKQ 566
+ ARRTES D +E L++ + +FG+ +++IEKA L+VTL + T EI+ +A+F DYPN A +D + + + K + PLN+LFMHYF++K VE++ +I+ TVFN ++H++F+ N G + EN T+ ++D + ++ R + P L+IR A++
Sbjct: 22 GVCARRTESSDVHHLEALVSPATEQLFGRVIPVSLIEKANLAVTLCNDTNEIIAHAAFLDYPNTACVDQAEWPSWMCKHFDSGKCTPLNTLFMHYFVAKSGVETDCAKQIIRTVFNAVPDLHFVFLLLKKNASPGAVLENIFTKMKMHGHVSDPGGSLYVCHRHNHFPILHIRQARE 198
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Nematostella
Match: EDO37268 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG85]) HSP 1 Score: 977.237 bits (2525), Expect = 0.000e+0 Identity = 525/1208 (43.46%), Postives = 747/1208 (61.84%), Query Frame = 3
Query: 60 ARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLK-ECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIPENF--GTQFTQIKSITDYKNWF---------ILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPSNDSQTSSTEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNASIRSGLNDIPNNFEFPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNEHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXX--XXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQE---GYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
ARRTESLDA +I KL+ + + +FG+ N++NIIEK+ L+VTL + ++V +A+F+DYPNI +D +S W+ +K K +C A PLNSLFM+YF++KP+ +EI+ TVFN +HYIF+ +P + G T++ YK F + R + P L+IR A+ ED DDLMPIFN Q+ +L +YG F+LAE+++AQ+ + KCLVA+V G AVGF+S+ + + +LN F LE F +K +I + P N+S P ++H+ + + + R P+ G +A IQLF I+E YEMRSIDFL F FP+RDY ++T+P LV EF LL+ F+R++P+ L ELY +H+ LI +F +R D + I+ +I +K S IL D+EQ++ ARR G L +VAEC+ ++VG V+++EEDIEYIRSHY+IEDF+YF HH R EH H+ H +NP+F++ SK FLKE +R + K+ +YYPV+ +AS + HS+VT+L DLVPI RRQI+Y +++L GNAP+ERILQ +E + L H NRKL +EPKV IN RIVVVGAS G+SFLE+ F PHL+FNNL L+SP GLP D+L+ + + +LR ++VVKG MTAIDR K++ ++G + +PYD+++I TG Q+ +P PT A I TT E Y ++ PDN+ VN K++++V + + ++ K ++YG + E++ + +LS GI R+ V+PP N+ +EEA + L +GV +H Y +A++ND N +S +FT+ PLR++C+ F + +K V++ AF+A+NDSCLVFD RLV+D F TND IRAAGP+TK++RRY+ E WSHA FNSR VG+EL++ L LFDPTL EE L+P+Y + S +LPGG+HYL V +P L+IPL +L QP YG L TG E GYFRLH+NQY+ VETITC KK+ N LYG+HER LNNL RF+E LI+D + FF ++W +A +HDRF D +EEI+ELL+ + S S EE VR M+ E + L+++QR+ L D + +S AK ++QRL+SF++YN YHLPMYAKP MV
Sbjct: 12 ARRTESLDAPDILKLVTATTDKLFGRVNVVNIIEKSNLAVTLVNSANKVVAHAAFFDYPNITGVDQAS-WDTWLKSKYDCDKATPLNSLFMNYFVAKPDFAYGCAVEIIRTVFNAVPFLHYIFL-----AVPRSVETGAALTEVFKPMSYKESFTGKLNCEVQVCHRHEHCPKLHIRPARVEDHDDLMPIFNRQNDVLTSMYGNFFLAELIEAQDSENKCLVADVNGTAVGFMSICSQMEARILNRCFDLEPFNRLQKTA------DIGEEPDDPINES---------PEIIHKLSE---------------EHLVQRCPTPPH---------------GPCSAFCIQLFCIDEKYEMRSIDFLPAAFAQFPDRDYCVLTMPHLVSEFPLLQAFIRVTPKRHSTLSQELYVYHRWGLIESFNVRPCISSDSDAIRKVIKKLKASDKILMDVEQYNRARRDPDGTELQVFVAECIGQVVGAAVLRREEDIEYIRSHYSIEDFVYFNHHQREEHAHLHHLILNPVFQQYSKHFLKEVLRLAHKSCLYYPVFPVYASGSVTKNHSVVTSLNDLVPIAARRQIIYPVKELGGNAPSERILQEKEAFALNHLNRKLTLEPKVVINARIVVVGASDVGISFLETFVFCPHLRFNNLTLVSPQGLPGQTAPDKLVNSCLPSSMCYDDDIYANMSLRTWINVVKGSMTAIDRTNKILKVSGGFGVPYDYLVICTGQQFQVPAPTGADISTLVTTSEVPRPRTAVYRGML---------PDNVFTVNSHGDCAKVVKWVNNYFLNSQGKALVYGCTLEAFTFVQGLLSAGIPADRLVMVQPPPPVPSC-FNNIDIEEATDQALQASGVEVHVGYVLAEWNDGKYDSN-LSCATFTSENKPLRVDCQAFFCFQEKRVDFQAFKAINDSCLVFDGRLVVDANFRTNDPFIRAAGPLTKYQRRYHAESWSHANFNSREVGDELARSMLALFDPTLEGFMPGPVSEEEDKLVPLYKKPKMVSAVLPGGYHYLHVGKPGLNIPLDSLMVQPEYGRELLTGNAKEAESGPGYFRLHVNQYRSVETITCYSKKSLDTTNLKCLYGIHERYLNNLLQRFDEGLIQDFYSFFQESWCLAVFHDRFNDFREEIRELLVNKPSDDVLSLEEKVRKMIDEDLVLSKDQRRNLSDNYVSSPAKKAIEQRLLSFLSYNGYHLPMYAKPGMV 1157
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Medaka
Match: CFAP61 (cilia and flagella associated protein 61 [Source:NCBI gene;Acc:101163868]) HSP 1 Score: 508.449 bits (1308), Expect = 8.497e-160 Identity = 294/859 (34.23%), Postives = 476/859 (55.41%), Query Frame = 3
Query: 1050 NAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNEHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPD 3626
NA I+ F + + +RS+D +Q +F LFP+ DY + T EF L+NF+R+ P + P LY FH+ L +R+A D+ + ++ ++ ++++L DL+ F+ V L AYVA+ ++IVG++++K E+D++Y+R+HYNI+++I F+ + EH HI+HF + P LSK F KE +R + K+ +YY Y S + L L VPI PR+QI+Y +++L +AP+ R+ + Q + L+ RK ++P+ INTRIVVVGAS TGLSFLE+L P LKFNNL L+S +G P + +++ + ++ K L L + ++VVKG M +I+RK K + ++G +PY+++I+ TG+QY++P T + N P+ + Q +P + + +VP NL +N+ ++ N + + IIYG + + Y + T+LS+GI G RIH V PP + V + VVE AV L A VH+H ++ +AQ N SDE P+ ++SV+FT PL L+C +F++ K ++ ++ S L+ D RLVI F T D SI AGP+T+F Y++++WSHA FNS+ VG++L++ L D + + E LIPIY + +++ LPGG ++L V++PS P + ++T GV YF + L+ VETI CL + PI NY+ LYG HE+ L + R+ + L++DL+ FF W M +HDR+ DL++E+ E + + + EE + F ++ ++TV F+A N LPM+++P+
Sbjct: 304 NAFCIRFFLTKKRFNLRSVDCIQYMFQLFPDLDYCIFTFDLSCAEFGFLQNFLRVPTEPTNLSPCALYIFHRSGL-GRVGVRKAVDSDRAAVSDLVKDLNCNKSLLQDLDSFY---NDPVSVMLQAYVAQMDSQIVGILIVKDEQDVDYLRAHYNIDNYIQFSQYRSEEHVHIRHFVLKPFLGLLSKHFFKEVLRLAHKSCLYYRTYPRHCSHQDSCVDPLDFVLNYAVPISPRKQIIYPLEELGNDAPSIRLTEEQAPFALSLIRRKFLVQPRRNINTRIVVVGASDTGLSFLETLCLRPKLKFNNLALVSTHGFPGDCDHNDM--GFLSTSHAYNSKDLAL--IHSNINVVKGKMVSINRKSKYVLVSGVGKVPYNYLILCTGLQYSVPNVTVENVSN-PSNDQLQPQPTEQTN--------PGVVPSNLFTLNNVHDCMAARHWLCANFLDQKDNAIIYGDNIDVYISVETLLSLGIPGARIHLVLPPPEPAVCTFPNSVVENAVAAALKVANVHVHRDFVLAQMN-SDEHPDRLTSVTFTKDSEPLHLQCGVFLNLSGKEIDCDVLESIQKSLLLSDDRLVIRATFLTTDSSIYGAGPLTRFSHWYHSDEWSHANFNSKEVGQDLAETLLSKLDAIVENLEEESPVEGRLIPIYKQAKIQAGKLPGGFNFLHVTKPS---PTTARRPFTPTTQIVTGGVK--TGNYFCIELDCNGLVETIICLSLEPLPISNYLTLYGKHEKLLGQMLRRYRQGLLQDLYSFFRQRWCMPIFHDRYSDLEKELWEKVRLKDTGSQRVTEE--------------DSDSSPPGSFLDAEGRATVRNVTQRFLANNKDLLPMFSEPE 1125 HSP 2 Score: 83.5741 bits (205), Expect = 1.137e-15 Identity = 68/286 (23.78%), Postives = 132/286 (46.15%), Query Frame = 3
Query: 75 SLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIV-KLKECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYI-FINTDKGKIPENFGTQFTQIKSITDYKNWFI---LKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDI---NIDLLNYGFYLEAFEGFKK-------------------PVQTVNEENIEQLAKKPS 851
S D IE L S S IFG+ N++ + +KA ++T+ ++ +IV +A F D+P I ++ + W + + K P LN+LF+H F+++ + + + I+ T F+ + YI ++ + ++ F +S TD + RE P +++R + D++++M I + ++ D ++ +++ + E VGFI V+ I N+++L++ F L F+GF K P T+ E+ Q+ + PS
Sbjct: 27 SADIEWIESLTTSTSP-IFGRVNVVQLEDKASFALTVVNENQDIVAHAVFVDHP-IGDLVDQAQWEQFLHKHFSSPQCTSLNTLFLHLFVAREDFATTTVHTIMRTAFHVVPEVEYICLVSPNVAELEPALQVIFDPFQSRTDSALQCLACFCCREKIYPQVHMRPFRASDLNEVMDIIDGETASSSD---------SIELESEHCHAITVEADKAVVGFIKVSDVIDIYNLEILDH-FDLRQFKGFYKIQEKQAEAAAAYLSGEEQEPSSTLEEQRETQMTEAPS 300
BLAST of cilia- and flagella-associated protein 61 vs. Planmine SMEST
Match: SMESG000059955.1 (SMESG000059955.1) HSP 1 Score: 2379.36 bits (6165), Expect = 0.000e+0 Identity = 1189/1193 (99.66%), Postives = 1192/1193 (99.92%), Query Frame = 3
Query: 54 MYARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIPENFGTQFTQIKSITDYKNWFILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPSNDSQTSSTEHSVPVVVHXXXXXXXXXXXXXXXXXXFHNALFRFPSNASIRSGLNDIPNNFEFPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQYMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNEHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDXXXXXXXXXXXXXXXXXXXYYDSILKSCILPGGHHYLSVSRPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 3632
MYARRTESLDAVEIEKLINSNSIYIFGKPNLI+IIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIPENFGTQFTQIKSITDYKNWFILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPSNDSQTSSTEHSVPVVVHEENIETSLSETSTEKSISFHNALFRFPSNASIRSGLNDIPNNFEFPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQ MIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNEHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDPTLVPVVTPPVEEVPLIPIYYDSILKSCILPGG+HYLSVS+PSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV
Sbjct: 1 MYARRTESLDAVEIEKLINSNSIYIFGKPNLISIIEKALLSVTLTSKTGEIVGYASFYDYPNIAEIDTSSDWNEIVKLKECPLANPLNSLFMHYFLSKPEVESNILMEIVNTVFNTASNIHYIFINTDKGKIPENFGTQFTQIKSITDYKNWFILKREAYMPTLYIRAAKQEDMDDLMPIFNAQSTILKDIYGEFYLAEMVDAQNDQTKCLVAEVGGFAVGFISVTTDINIDLLNYGFYLEAFEGFKKPVQTVNEENIEQLAKKPSNDSQTSSTEHSVPVVVHEENIETSLSETSTEKSISFHNALFRFPSNASIRSGLNDIPNNFEFPGESNAIIIQLFAINEAYEMRSIDFLQNVFDLFPNRDYLLITVPFLVPEFTLLENFVRISPRPGIILPHELYCFHKGSLISNFKIRQACKKDQEEIQDMIINMKLSRNILNDLEQFHLARRFDTGVSLFAYVAECMNKIVGVMVMKQEEDIEYIRSHYNIEDFIYFTHHLRSEHGHIKHFAINPIFRRLSKLFLKECMRKSRKTSVYYPVYKPWASQKLLNEHSLVTNLQDLVPIRPRRQILYDIQKLEGNAPTERILQVQEGYCLTHFNRKLAMEPKVTINTRIVVVGASTTGLSFLESLTFSPHLKFNNLFLLSPNGLPDNHPTDELIEQLMGKDFDFSKKKLELSALRLQVHVVKGYMTAIDRKKKLISINGKYLLPYDHMIIATGMQYTIPCPTEAKIKNFPTTKESQNKPDRRYSELMFKKHMEKIVPDNLMVVNDPFGAFKLLEFVRHNLMLNESKIIIYGHSFESYCCLHTILSMGIMGYRIHFVKPPVDEEVFPLNDPVVEEAVYKTLDEAGVHIHDNYCVAQFNDSDEVPNWISSVSFTTHGPPLRLECELFVSYYKKVVNYSAFRAMNDSCLVFDARLVIDTFFHTNDLSIRAAGPVTKFKRRYYNEQWSHARFNSRVVGEELSKVFLRLFDPTLVPVVTPPVEEVPLIPIYYDSILKSCILPGGYHYLSVSKPSLDIPLSTLTNQPNYGSVLTTGVPYCQEGYFRLHLNQYKKVETITCLRKKAYPIENYVQLYGVHERALNNLESRFNENLIKDLFEFFDDTWAMAFYHDRFRDLKEEIKELLMTRSSPCNASFEETVRNMMVEGVELTREQRKELMDEFRNSNAKSTVDQRLISFIAYNYYHLPMYAKPDMV 1193 The following BLAST results are available for this feature:
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 4
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 3
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of cilia- and flagella-associated protein 61 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of cilia- and flagella-associated protein 61 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of cilia- and flagella-associated protein 61 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of cilia- and flagella-associated protein 61 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30000512 ID=SMED30000512|Name=cilia- and flagella-associated protein 61|organism=Schmidtea mediterranea sexual|type=transcript|length=3735bpback to top protein sequence of SMED30000512-orf-1 >SMED30000512-orf-1 ID=SMED30000512-orf-1|Name=SMED30000512-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1194bp MYARRTESLDAVEIEKLINSNSIYIFGKPNLINIIEKALLSVTLTSKTGEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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