G_PROTEIN_RECEP_F1_2 domain-containing protein

Overview
NameG_PROTEIN_RECEP_F1_2 domain-containing protein
Smed IDSMED30000511
Length (bp)1527
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30000511) t-SNE clustered cells

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30000511) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30000511) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30000511) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30000511

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30000511h1SMcG0010132 SmedASXL_011586SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30000511h1SMcG0010132 dd_Smed_v4_16018_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30000511h1SMcG0010132 dd_Smed_v4_16018_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30000511h1SMcG0010132 dd_Smed_v4_16018_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
muscle cellSMED30000511h1SMcG0010132 dd_Smed_v4_16018_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30000511h1SMcG0010132 dd_Smed_v4_16018_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30000511h1SMcG0010132 dd_Smed_v4_16018_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30000511h1SMcG0010132 dd_Smed_v4_16018_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
anterior sideSMED30000511h1SMcG0010132 dd_Smed_v4_16018_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30000511h1SMcG0010132 dd_Smed_v6_16018_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30000511h1SMcG0010132 OX_Smed_1.0.02229ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: sprr-1 (Sex Peptide Receptor (Drosophila) Related [Source:UniProtKB/TrEMBL;Acc:G5EEU4])

HSP 1 Score: 78.9518 bits (193), Expect = 2.111e-15
Identity = 43/115 (37.39%), Postives = 69/115 (60.00%), Query Frame = 3 
Query:  363 PYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFTENILFAYFGFN---LLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCT 698
            P+++ +T  TN+ + +VLS   + TPTN +LLA+AVT++LTGL  LP +  +Y +S      +  L +++      +    P+ FHT ++WLT+ LA QR IY+   + V K CT
Sbjct:   37 PFIVTLTVATNSFIVVVLSHKYLRTPTNYVLLAMAVTELLTGLSCLPWFTYYYTLSGYKNDLQTGLPSFWCDMIPYMAAFLPSIFHTMAIWLTVYLAIQRYIYICVPSLVRKFCT 151
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: sprr-1 (Sex Peptide Receptor (Drosophila) Related [Source:UniProtKB/TrEMBL;Acc:G5EEU4])

HSP 1 Score: 78.9518 bits (193), Expect = 2.111e-15
Identity = 43/115 (37.39%), Postives = 69/115 (60.00%), Query Frame = 3 
Query:  363 PYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFTENILFAYFGFN---LLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCT 698
            P+++ +T  TN+ + +VLS   + TPTN +LLA+AVT++LTGL  LP +  +Y +S      +  L +++      +    P+ FHT ++WLT+ LA QR IY+   + V K CT
Sbjct:   37 PFIVTLTVATNSFIVVVLSHKYLRTPTNYVLLAMAVTELLTGLSCLPWFTYYYTLSGYKNDLQTGLPSFWCDMIPYMAAFLPSIFHTMAIWLTVYLAIQRYIYICVPSLVRKFCT 151
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: sprr-2 (Sex Peptide Receptor (Drosophila) Related [Source:UniProtKB/TrEMBL;Acc:Q93704])

HSP 1 Score: 67.3958 bits (163), Expect = 1.022e-11
Identity = 40/122 (32.79%), Postives = 67/122 (54.92%), Query Frame = 3 
Query:  303 LPVPQYDLKSLQYLLVYKISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSN-STLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYV 665
            LP+ Q+D  +L+ ++  +I P ++      N  V +VLS+  MITPTN++L  +A+ ++L GL PLP  +  + M N        + + Y     +  FP  FH  ++WLT+ LA QR + +
Sbjct:   48 LPLTQFD--NLEIVVYGQIFPILVLFAVFANAAVALVLSKKHMITPTNVVLKYMAIAELLVGLVPLPWTLFFFSMGNIKETHRLELWWCYLQKYSMDAFPPVFHMIAMWLTVLLAAQRYVSI 167
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: sprr-2 (Sex Peptide Receptor (Drosophila) Related [Source:UniProtKB/TrEMBL;Acc:Q93704])

HSP 1 Score: 67.3958 bits (163), Expect = 1.022e-11
Identity = 40/122 (32.79%), Postives = 67/122 (54.92%), Query Frame = 3 
Query:  303 LPVPQYDLKSLQYLLVYKISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSN-STLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYV 665
            LP+ Q+D  +L+ ++  +I P ++      N  V +VLS+  MITPTN++L  +A+ ++L GL PLP  +  + M N        + + Y     +  FP  FH  ++WLT+ LA QR + +
Sbjct:   48 LPLTQFD--NLEIVVYGQIFPILVLFAVFANAAVALVLSKKHMITPTNVVLKYMAIAELLVGLVPLPWTLFFFSMGNIKETHRLELWWCYLQKYSMDAFPPVFHMIAMWLTVLLAAQRYVSI 167
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: SPR (gene:FBgn0029768 transcript:FBtr0344824)

HSP 1 Score: 114.775 bits (286), Expect = 2.743e-27
Identity = 113/358 (31.56%), Postives = 172/358 (48.04%), Query Frame = 3 
Query:  363 PYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLP--IYIMHYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYAS---LRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYV----ILKYIDRIKISRNWSEITNIC----NFIILISYPFNFVIYCIMSKKFRDTFKE 1397
            P+++ IT  +N+L+ +VLS+ +M TPTN +L+ +A+ DMLT +FP P   Y+  +G     L   ++  AY  FN   I P   HT SVWLT+ LA QR IYV         CT       ++ I +LAFL     F   F++ Y   V        E   L  S W             H    V  +Y S    R++F+H++PCI+L  L + L   ++Q     ++L+  +N +K        E    R++  T+                   ML+VV+ VF+  EIP+  V  +++    I++++D          + NIC    NF ++ SYP NF IYC MS++FR+TFKE
Sbjct:   97 PFLLIITIISNSLIVLVLSKKSMATPTNFVLMGMAICDMLTVIFPAPGLWYMYTFGNHYKPLHPVSMCLAYSIFN--EIMPAMCHTISVWLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQLPRF---FDRTYMPLVIEWNGSPTEVCHLETSMW------------VHDYIGVDLYYTSYYLFRVLFVHLLPCIILVTLNILLFAAMRQAQE-RRKLLFRENRKK--------ECKKLRETNCTT------------------LMLIVVVSVFLLAEIPIAVVTAMHIVSSLIIEFLD--------YGLANICIMLTNFFLVFSYPINFGIYCGMSRQFRETFKE 402
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: SPR (gene:FBgn0029768 transcript:FBtr0339781)

HSP 1 Score: 114.775 bits (286), Expect = 2.743e-27
Identity = 113/358 (31.56%), Postives = 172/358 (48.04%), Query Frame = 3 
Query:  363 PYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLP--IYIMHYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYAS---LRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYV----ILKYIDRIKISRNWSEITNIC----NFIILISYPFNFVIYCIMSKKFRDTFKE 1397
            P+++ IT  +N+L+ +VLS+ +M TPTN +L+ +A+ DMLT +FP P   Y+  +G     L   ++  AY  FN   I P   HT SVWLT+ LA QR IYV         CT       ++ I +LAFL     F   F++ Y   V        E   L  S W             H    V  +Y S    R++F+H++PCI+L  L + L   ++Q     ++L+  +N +K        E    R++  T+                   ML+VV+ VF+  EIP+  V  +++    I++++D          + NIC    NF ++ SYP NF IYC MS++FR+TFKE
Sbjct:   97 PFLLIITIISNSLIVLVLSKKSMATPTNFVLMGMAICDMLTVIFPAPGLWYMYTFGNHYKPLHPVSMCLAYSIFN--EIMPAMCHTISVWLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQLPRF---FDRTYMPLVIEWNGSPTEVCHLETSMW------------VHDYIGVDLYYTSYYLFRVLFVHLLPCIILVTLNILLFAAMRQAQE-RRKLLFRENRKK--------ECKKLRETNCTT------------------LMLIVVVSVFLLAEIPIAVVTAMHIVSSLIIEFLD--------YGLANICIMLTNFFLVFSYPINFGIYCGMSRQFRETFKE 402
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: SPR (gene:FBgn0029768 transcript:FBtr0070778)

HSP 1 Score: 114.775 bits (286), Expect = 2.743e-27
Identity = 113/358 (31.56%), Postives = 172/358 (48.04%), Query Frame = 3 
Query:  363 PYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLP--IYIMHYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYAS---LRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYV----ILKYIDRIKISRNWSEITNIC----NFIILISYPFNFVIYCIMSKKFRDTFKE 1397
            P+++ IT  +N+L+ +VLS+ +M TPTN +L+ +A+ DMLT +FP P   Y+  +G     L   ++  AY  FN   I P   HT SVWLT+ LA QR IYV         CT       ++ I +LAFL     F   F++ Y   V        E   L  S W             H    V  +Y S    R++F+H++PCI+L  L + L   ++Q     ++L+  +N +K        E    R++  T+                   ML+VV+ VF+  EIP+  V  +++    I++++D          + NIC    NF ++ SYP NF IYC MS++FR+TFKE
Sbjct:   97 PFLLIITIISNSLIVLVLSKKSMATPTNFVLMGMAICDMLTVIFPAPGLWYMYTFGNHYKPLHPVSMCLAYSIFN--EIMPAMCHTISVWLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQLPRF---FDRTYMPLVIEWNGSPTEVCHLETSMW------------VHDYIGVDLYYTSYYLFRVLFVHLLPCIILVTLNILLFAAMRQAQE-RRKLLFRENRKK--------ECKKLRETNCTT------------------LMLIVVVSVFLLAEIPIAVVTAMHIVSSLIIEFLD--------YGLANICIMLTNFFLVFSYPINFGIYCGMSRQFRETFKE 402
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: MsR1 (gene:FBgn0035331 transcript:FBtr0330187)

HSP 1 Score: 61.2326 bits (147), Expect = 1.192e-9
Identity = 39/106 (36.79%), Postives = 57/106 (53.77%), Query Frame = 3 
Query:  357 ISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFTENILFAYFGF-NLLTIFPTTFHTASVWLTITLAFQRVIYVKF 671
            +S  V  +    NTL  IVL+R  M +PTN IL  +AV D+   L  +P  I  Y +++S    E + +++  F    +IF    HT S+WLT+TLA  R I V +
Sbjct:   31 VSLVVCILGTIANTLNIIVLTRREMRSPTNAILTGLAVADLAVMLEYIPYTIHDYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGY 136
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: MsR1 (gene:FBgn0035331 transcript:FBtr0072887)

HSP 1 Score: 60.8474 bits (146), Expect = 1.458e-9
Identity = 39/106 (36.79%), Postives = 57/106 (53.77%), Query Frame = 3 
Query:  357 ISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFTENILFAYFGF-NLLTIFPTTFHTASVWLTITLAFQRVIYVKF 671
            +S  V  +    NTL  IVL+R  M +PTN IL  +AV D+   L  +P  I  Y +++S    E + +++  F    +IF    HT S+WLT+TLA  R I V +
Sbjct:   31 VSLVVCILGTIANTLNIIVLTRREMRSPTNAILTGLAVADLAVMLEYIPYTIHDYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGY 136
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8SWR3|SPR_DROME (Sex peptide receptor OS=Drosophila melanogaster OX=7227 GN=SPR PE=1 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 2.749e-26
Identity = 113/358 (31.56%), Postives = 172/358 (48.04%), Query Frame = 3 
Query:  363 PYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLP--IYIMHYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYAS---LRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYV----ILKYIDRIKISRNWSEITNIC----NFIILISYPFNFVIYCIMSKKFRDTFKE 1397
            P+++ IT  +N+L+ +VLS+ +M TPTN +L+ +A+ DMLT +FP P   Y+  +G     L   ++  AY  FN   I P   HT SVWLT+ LA QR IYV         CT       ++ I +LAFL     F   F++ Y   V        E   L  S W             H    V  +Y S    R++F+H++PCI+L  L + L   ++Q     ++L+  +N +K        E    R++  T+                   ML+VV+ VF+  EIP+  V  +++    I++++D          + NIC    NF ++ SYP NF IYC MS++FR+TFKE
Sbjct:   97 PFLLIITIISNSLIVLVLSKKSMATPTNFVLMGMAICDMLTVIFPAPGLWYMYTFGNHYKPLHPVSMCLAYSIFN--EIMPAMCHTISVWLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQLPRF---FDRTYMPLVIEWNGSPTEVCHLETSMW------------VHDYIGVDLYYTSYYLFRVLFVHLLPCIILVTLNILLFAAMRQAQE-RRKLLFRENRKK--------ECKKLRETNCTT------------------LMLIVVVSVFLLAEIPIAVVTAMHIVSSLIIEFLD--------YGLANICIMLTNFFLVFSYPINFGIYCGMSRQFRETFKE 402
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q93704|SPRR2_CAEEL (Sex peptide receptor-related protein 2 OS=Caenorhabditis elegans OX=6239 GN=sprr-2 PE=2 SV=2)

HSP 1 Score: 67.3958 bits (163), Expect = 1.300e-10
Identity = 40/122 (32.79%), Postives = 67/122 (54.92%), Query Frame = 3 
Query:  303 LPVPQYDLKSLQYLLVYKISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSN-STLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYV 665
            LP+ Q+D  +L+ ++  +I P ++      N  V +VLS+  MITPTN++L  +A+ ++L GL PLP  +  + M N        + + Y     +  FP  FH  ++WLT+ LA QR + +
Sbjct:   48 LPLTQFD--NLEIVVYGQIFPILVLFAVFANAAVALVLSKKHMITPTNVVLKYMAIAELLVGLVPLPWTLFFFSMGNIKETHRLELWWCYLQKYSMDAFPPVFHMIAMWLTVLLAAQRYVSI 167
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A193KUL2 (GCR111 OS=Schmidtea mediterranea OX=79327 GN=gcr111 PE=2 SV=1)

HSP 1 Score: 189.119 bits (479), Expect = 3.289e-51
Identity = 147/404 (36.39%), Postives = 227/404 (56.19%), Query Frame = 3 
Query:  225 SSYSSVKLLDDFQKSLQSENTLKSICLPVPQYDLKSLQYLLVYKISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIM-HYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYASLRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLM------ASKNNRK--------LSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYVILKYIDRIKISRNWSEITNICNFIILISYPFNFVIYCIMSKKFRDTF 1391
            +++S+ +  +++  S+     L + C+ +      +L+ +L+++ISPY+I     TN L+C+ L+RP MITPTNIIL+ IA++DMLTGL PLPIYIM ++      L      F Y  + L +  PT FHT S+W T+ LA QRVIYVKF+  V++ CT  I+     +  IL+ + HS +F  SF   +            E +  S  + +NF+     +KC+ FS++    Y  LRI  +H++PC  LT+LT  L+ VL+QK +L   L+       S++  K        +S+ ++  + S +++   T D              STSKML++VL++F+ VEIP+G V+T Y +L+ +        W ++TN CNF+IL+SYP NF IYC M  KFR TF
Sbjct:    6 ANFSNFQSANNYPDSVNVLGYLNN-CITIELSLFDNLESILLFQISPYIIGFVTMTNLLICLTLTRPFMITPTNIILMGIALSDMLTGLLPLPIYIMRNFSYQFLELEKSYYQFLYVNYYLTSFLPTVFHTTSIWFTLQLALQRVIYVKFSNNVSRFCTTEIAWKMFIITPILSSIFHSPDFIVSFRNSFS-----------ENNNGSFGK-KNFA-----IKCNVFSDTSFAIYTILRITLVHLIPCCSLTVLTNILIFVLRQKYHLHNLLIPQASIVQSRDPEKRSLNVLLNVSSHNEAAKRSRFKQGSRTID------------IQSTSKMLLMVLIMFLLVEIPIGGVITAYTLLRLLGLKLNPVIWKQVTNTCNFVILVSYPINFFIYCAMLPKFRLTF 379
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A193KUJ4 (GCR057 OS=Schmidtea mediterranea OX=79327 GN=gcr057 PE=2 SV=1)

HSP 1 Score: 149.443 bits (376), Expect = 3.013e-36
Identity = 130/355 (36.62%), Postives = 188/355 (52.96%), Query Frame = 3 
Query:  342 LLVY-KISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFT--ENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYASLRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYVILK-YIDRIKISRNWSEITNICNFIILISYPFNFVIYCIMSKKFRDTFK 1394
            LLVY KI   VI I   TNT +C++L+R  MI+ TN+IL AIA+ D LTGLFPLP Y+    + N + F+   +  F YF +  + + PT  HT S+WLT+ LA QR IYV   T    +CT + SI T   I +L+ + H      SF+ YY     +QT   PE                 I+KC+   E ++ +Y S R V ++V+PC+LLT+  ++L++ ++          A K+ R L  T  K E    ++  +TS  +                  +VVL +F+ VEIP G  +TLY+I K +         W ++ +ICN +I+ SYP NFVIYCIMS+ FR+T K
Sbjct:   49 LLVYSKILIPVILIVCFTNTCICLILTRRHMISATNMILTAIAIADFLTGLFPLPFYV----IKNFSFFSSIRSRTFGYFYYFSVVVIPTICHTISIWLTVALAVQRFIYVSLPTEAKNICTVKTSIYTILTICVLSLVFHLQLSIVSFDSYYFYPCKHQT---PE---------------FVILKCNWTVELLIIYYWS-RTVLMNVIPCLLLTVFILSLIVAVRS---------AEKHRRVLLQTSQKKESRRSKEFYSTSKML------------------LVVLCLFLIVEIPNGIAITLYMIQKSFSSNNSNDSFWGKMNSICNILIIFSYPLNFVIYCIMSRNFRETLK 353
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A193KUJ2 (GCR082 OS=Schmidtea mediterranea OX=79327 GN=gcr082 PE=2 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 2.108e-35
Identity = 120/386 (31.09%), Postives = 187/386 (48.45%), Query Frame = 3 
Query:  258 FQKSLQSENTLKSI------CLPVPQYDLKSLQYLLVYKISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYASLRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYVILKYIDRIKISRN-WSEITNICNFIILISYPFNFVIYCIMSKKFRDTFK 1394
            F +S++  +T+ S       C P P         LL  K+ P++I     TN  +CIVL++  M +PTN+IL+++A+ DM TG+FPLP+Y+++   +  T +  NI  +   F L  + PT  HTAS+WLT+ LA QR IY+     V  +C  + SI     +  L+   +    +  F K+  +C DN T  L                   +MKC      ++  Y   R++ +HV PC LL   +V L+I +K+          +   RKL     K E  +     NT+  +                 LVVV+ +F+ VE+P G  +T+Y I + +     S     ++T+ICN   +ISY FNF +YC MSK+FR+T+K
Sbjct:    9 FYQSVEENSTVTSSLELELRCGPYPSIKKPEFSLLLESKVLPFIIIFLMSTNISICIVLNKRHMRSPTNVILMSLALADMFTGVFPLPVYLINNYPTFLTQYQNNITISVAIFVLNVVLPTICHTASIWLTVILAIQRYIYITMPLKVDHICKIKNSIKMVIAVIFLSICFNWPLISPQFLKFNLVCSDNSTHIL-------------------VMKCHSSGSRLMIIYYFSRLLLMHVAPCALLLSFSVLLIIAMKK---------VAIRRRKLLNLSKKAESRMLGWDSNTTSRM-----------------LVVVVTIFLIVELPNGIFITIYTISQMLFITIFSDELLGKLTHICNLATMISYLFNFFVYCTMSKQFRETYK 349
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A443RIG9 (Sex peptide receptor-like protein OS=Dinothrombium tinctorium OX=1965070 GN=B4U79_00104 PE=4 SV=1)

HSP 1 Score: 134.42 bits (337), Expect = 7.053e-31
Identity = 118/365 (32.33%), Postives = 176/365 (48.22%), Query Frame = 3 
Query:  333 LQYLLVY--KISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKC-----SHFSESVLFW-YASLRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLMASKNNR-KLSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYVILKYID-RIKISRNWSEITNICNFIILISYPFNFVIYCIMSKKFRDTFKE 1397
            ++YL++    I P+++ IT   NTL+ +VLS+  M TPTN++LLA+A++D+LT LFP P Y   + + N +     I   Y    ++ + P  FHTAS+WLT+ LA QR IYV   T     CT             +  ++ ++ F +     +Q      T +   +      EW+N S+ G          S F+E+V F  Y   RI+F+H+ PC  L +L V           L K L A++  R KL   + K E    R S  T+                   ML+VV+ VF+  EIP+     L+V    +D  I   +  +      NF I++SYP NF IYC MS++FR+TFKE
Sbjct:   70 IEYLIIMFGYIMPFLLIITIVANTLIVVVLSQRHMRTPTNLVLLAMAISDLLTLLFPAPWYFYMFTLGNHSKILYPIAACYSFHCMIEVIPAFFHTASIWLTLVLAGQRYIYVCHPTVANSWCT-------------VPRVIRAMFFVFILAFLHQ-----STRFFDRSFSPVQFEWKNSSHWGCAYSTASWVNSVFTETVYFTCYYGFRIIFVHIGPCAALVVLNVL----------LFKALKAAQKKRDKLFKENRKSECKKLRDSNCTT------------------LMLIVVVTVFLATEIPLAVTTVLHVAQNVLDLLIADYKTLNSTILFTNFFIMLSYPVNFAIYCGMSRQFRETFKE 388
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: V4BXC4 (G_PROTEIN_RECEP_F1_2 domain-containing protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_94766 PE=4 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 1.337e-30
Identity = 113/348 (32.47%), Postives = 182/348 (52.30%), Query Frame = 3 
Query:  357 ISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYASLRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYVILKYIDRIKISRNWSEITNI-CNFIILISYPFNFVIYCIMSKKFRDTFKE 1397
            ISP ++F+T   N++VCIVL +  M +PTN +L+ +A++DMLTG+FPLPI++  +       FT       + + L  + PT FHTAS+WLT+ LA QR IYV  +      CT   +I  +  I+++A L     F   F+ Y+   V    +Y   T      E  +++ +  I+       S+ +W+   R++F+H++PCI L ++   L+  ++      +R+   + N+K              +SK   D             + T+ MLV V+ +F+ VE P+G +M L ++    +   IS+   +I +I  N  IL+SYPFNF IYC MSK+FR+TFK 
Sbjct:   12 ISPILVFLTIINNSMVCIVLLKRNMRSPTNTLLVGMAISDMLTGVFPLPIFLEFFATDRLKEFTPYSWCNAYKY-LAELLPTIFHTASIWLTMALAIQRYIYVCHSFKARTWCTIPNAIKGTIAIYVVAILSQCTRF---FDSYFVPVVLESAVYENRTVIGCIEEHEDWA-MANILYM-----SIYYWF---RVLFIHLIPCIFLVVMNALLIYAMRVAQ--VRRMQLLRQNKK-------------SESKKLKDS------------NCTTLMLVAVVGLFLLVEFPLGIIMILLIVSNTFEVHIISKETFQILSIFSNLFILLSYPFNFFIYCGMSKQFRETFKR 319
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000064707.1 (SMESG000064707.1)

HSP 1 Score: 695.656 bits (1794), Expect = 0.000e+0
Identity = 402/404 (99.50%), Postives = 403/404 (99.75%), Query Frame = 3 
Query:  198 MFSKFGDKCSSYSSVKLLDDFQKSLQSENTLKSICLPVPQYDLKSLQYLLVYKISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYASLRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYVILKYIDRIKISRNWSEITNICNFIILISYPFNFVIYCIMSKKFRDTFKETLCP 1409
            MFSKFGDKCSSYSSVKLLDDFQK+LQSENTLKSICLPVPQYDLKSLQYLLVYKISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRISIITSSLIFILAFLMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYASLRIVFLHVVPCILLTILTVTLLIVLKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDH LAKSRCSKDSSSSTSKMLVVVLLVFICVEIPMGTVMTLYVILKYIDRIKISRNWSEITNICNFIILISYPFNFVIYCIMSKKFRDTFKETLCP
Sbjct:    1 MFSKFGDKCSSYSSVKLLDDFQKNLQSENTLKSICLPVPQYDLKSLQYLLVYKISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRISIITSSLIFILAFLMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYASLRIVFLHVVPCILLTILTVTLLIVLKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDHTLAKSRCSKDSSSSTSKMLVVVLLVFICVEIPMGTVMTLYVILKYIDRIKISRNWSEITNICNFIILISYPFNFVIYCIMSKKFRDTFKETLCP 404
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000077911.1 (SMESG000077911.1)

HSP 1 Score: 189.119 bits (479), Expect = 9.148e-55
Identity = 147/404 (36.39%), Postives = 227/404 (56.19%), Query Frame = 3 
Query:  225 SSYSSVKLLDDFQKSLQSENTLKSICLPVPQYDLKSLQYLLVYKISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIM-HYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYASLRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLM------ASKNNRK--------LSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYVILKYIDRIKISRNWSEITNICNFIILISYPFNFVIYCIMSKKFRDTF 1391
            +++S+ +  +++  S+     L + C+ +      +L+ +L+++ISPY+I     TN L+C+ L+RP MITPTNIIL+ IA++DMLTGL PLPIYIM ++      L      F Y  + L +  PT FHT S+W T+ LA QRVIYVKF+  V++ CT  I+     +  IL+ + HS +F  SF   +            E +  S  + +NF+     +KC+ FS++    Y  LRI  +H++PC  LT+LT  L+ VL+QK +L   L+       S++  K        +S+ ++  + S +++   T D              STSKML++VL++F+ VEIP+G V+T Y +L+ +        W ++TN CNF+IL+SYP NF IYC M  KFR TF
Sbjct:    6 ANFSNFQSANNYPDSVNVLGYLNN-CITIELSLFDNLESILLFQISPYIIGFVTMTNLLICLTLTRPFMITPTNIILMGIALSDMLTGLLPLPIYIMRNFSYQFLELEKSYYQFLYVNYYLTSFLPTVFHTTSIWFTLQLALQRVIYVKFSNNVSRFCTTEIAWKMFIITPILSSIFHSPDFIVSFRNSFS-----------ENNNGSFGK-KNFA-----IKCNVFSDTSFAIYTILRITLVHLIPCCSLTVLTNILIFVLRQKYHLHNLLIPQASIVQSRDPEKRSLNVLLNVSSHNEAAKRSRFKQGSRTID------------IQSTSKMLLMVLIMFLLVEIPIGGVITAYTLLRLLGLKLNPVIWKQVTNTCNFVILVSYPINFFIYCAMLPKFRLTF 379
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000001877.1 (SMESG000001877.1)

HSP 1 Score: 149.443 bits (376), Expect = 9.080e-40
Identity = 130/355 (36.62%), Postives = 188/355 (52.96%), Query Frame = 3 
Query:  342 LLVY-KISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFT--ENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYASLRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYVILK-YIDRIKISRNWSEITNICNFIILISYPFNFVIYCIMSKKFRDTFK 1394
            LLVY KI   VI I   TNT +C++L+R  MI+ TN+IL AIA+ D LTGLFPLP Y+    + N + F+   +  F YF +  + + PT  HT S+WLT+ LA QR IYV   T    +CT + SI T   I +L+ + H      SF+ YY     +QT   PE                 I+KC+   E ++ +Y S R V ++V+PC+LLT+  ++L++ ++          A K+ R L  T  K E    ++  +TS  +                  +VVL +F+ VEIP G  +TLY+I K +         W ++ +ICN +I+ SYP NFVIYCIMS+ FR+T K
Sbjct:   49 LLVYSKILIPVILIVCFTNTCICLILTRRHMISATNMILTAIAIADFLTGLFPLPFYV----IKNFSFFSSIRSRTFGYFYYFSVVVIPTICHTISIWLTVALAVQRFIYVSLPTEAKNICTVKTSIYTILTICVLSLVFHLQLSIVSFDSYYFYPCKHQT---PE---------------FVILKCNWTVELLIIYYWS-RTVLMNVIPCLLLTVFILSLIVAVRS---------AEKHRRVLLQTSQKKESRRSKEFYSTSKML------------------LVVLCLFLIVEIPNGIAITLYMIQKSFSSNNSNDSFWGKMNSICNILIIFSYPLNFVIYCIMSRNFRETLK 353
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000001954.1 (SMESG000001954.1)

HSP 1 Score: 149.443 bits (376), Expect = 9.080e-40
Identity = 130/355 (36.62%), Postives = 188/355 (52.96%), Query Frame = 3 
Query:  342 LLVY-KISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFT--ENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYASLRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYVILK-YIDRIKISRNWSEITNICNFIILISYPFNFVIYCIMSKKFRDTFK 1394
            LLVY KI   VI I   TNT +C++L+R  MI+ TN+IL AIA+ D LTGLFPLP Y+    + N + F+   +  F YF +  + + PT  HT S+WLT+ LA QR IYV   T    +CT + SI T   I +L+ + H      SF+ YY     +QT   PE                 I+KC+   E ++ +Y S R V ++V+PC+LLT+  ++L++ ++          A K+ R L  T  K E    ++  +TS  +                  +VVL +F+ VEIP G  +TLY+I K +         W ++ +ICN +I+ SYP NFVIYCIMS+ FR+T K
Sbjct:   49 LLVYSKILIPVILIVCFTNTCICLILTRRHMISATNMILTAIAIADFLTGLFPLPFYV----IKNFSFFSSIRSRTFGYFYYFSVVVIPTICHTISIWLTVALAVQRFIYVSLPTEAKNICTVKTSIYTILTICVLSLVFHLQLSIVSFDSYYFYPCKHQT---PE---------------FVILKCNWTVELLIIYYWS-RTVLMNVIPCLLLTVFILSLIVAVRS---------AEKHRRVLLQTSQKKESRRSKEFYSTSKML------------------LVVLCLFLIVEIPNGIAITLYMIQKSFSSNNSNDSFWGKMNSICNILIIFSYPLNFVIYCIMSRNFRETLK 353
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000005296.1 (SMESG000005296.1)

HSP 1 Score: 146.747 bits (369), Expect = 5.863e-39
Identity = 120/386 (31.09%), Postives = 187/386 (48.45%), Query Frame = 3 
Query:  258 FQKSLQSENTLKSI------CLPVPQYDLKSLQYLLVYKISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFPLPIYIMHYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAFQRVIYVKFTTFVTKLCTNRXXXXXXXXXXXXXXXMHSVNFTYSFEKYYQICVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYASLRIVFLHVVPCXXXXXXXXXXXXXXKQKSNLSKRLMASKNNRKLSTTDDKIELSIYRKSKNTSDHIXXXXXXXXXXXXXXXXXXXXXXXXFICVEIPMGTVMTLYVILKYIDRIKISRN-WSEITNICNFIILISYPFNFVIYCIMSKKFRDTFK 1394
            F +S++  +T+ S       C P P         LL  K+ P++I     TN  +CIVL++  M +PTN+IL+++A+ DM TG+FPLP+Y+++   +  T +  NI  +   F L  + PT  HTAS+WLT+ LA QR IY+     V  +C  + SI     +  L+   +    +  F K+  +C DN T  L                   +MKC      ++  Y   R++ +HV PC LL   +V L+I +K+          +   RKL     K E  +     NT+  +                 LVVV+ +F+ VE+P G  +T+Y I + +     S     ++T+ICN   +ISY FNF +YC MSK+FR+T+K
Sbjct:    9 FYQSVEENSTVTSSLELELRCGPYPSIKKPEFSLLLESKVLPFIIIFLMSTNISICIVLNKRHMRSPTNVILMSLALADMFTGVFPLPVYLINNYPTFLTQYQNNITISVAIFVLNVVLPTICHTASIWLTVILAIQRYIYITMPLKVDHICKIKNSIKMVIAVIFLSICFNWPLISPQFLKFNLVCSDNSTHIL-------------------VMKCHSSGSRLMIIYYFSRLLLMHVAPCALLLSFSVLLIIAMKK---------VAIRRRKLLNLSKKAESRMLGWDSNTTSRM-----------------LVVVVTIFLIVELPNGIFITIYTISQMLFITIFSDELLGKLTHICNLATMISYLFNFFVYCTMSKQFRETYK 349
The following BLAST results are available for this feature:
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
sprr-12.111e-1537.39Sex Peptide Receptor (Drosophila) Related [Source... [more]
sprr-12.111e-1537.39Sex Peptide Receptor (Drosophila) Related [Source... [more]
sprr-21.022e-1132.79Sex Peptide Receptor (Drosophila) Related [Source... [more]
sprr-21.022e-1132.79Sex Peptide Receptor (Drosophila) Related [Source... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SPR2.743e-2731.56gene:FBgn0029768 transcript:FBtr0344824[more]
SPR2.743e-2731.56gene:FBgn0029768 transcript:FBtr0339781[more]
SPR2.743e-2731.56gene:FBgn0029768 transcript:FBtr0070778[more]
MsR11.192e-936.79gene:FBgn0035331 transcript:FBtr0330187[more]
MsR11.458e-936.79gene:FBgn0035331 transcript:FBtr0072887[more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2
Match NameE-valueIdentityDescription
sp|Q8SWR3|SPR_DROME2.749e-2631.56Sex peptide receptor OS=Drosophila melanogaster OX... [more]
sp|Q93704|SPRR2_CAEEL1.300e-1032.79Sex peptide receptor-related protein 2 OS=Caenorha... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A193KUL23.289e-5136.39GCR111 OS=Schmidtea mediterranea OX=79327 GN=gcr11... [more]
A0A193KUJ43.013e-3636.62GCR057 OS=Schmidtea mediterranea OX=79327 GN=gcr05... [more]
A0A193KUJ22.108e-3531.09GCR082 OS=Schmidtea mediterranea OX=79327 GN=gcr08... [more]
A0A443RIG97.053e-3132.33Sex peptide receptor-like protein OS=Dinothrombium... [more]
V4BXC41.337e-3032.47G_PROTEIN_RECEP_F1_2 domain-containing protein (Fr... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000064707.10.000e+099.50SMESG000064707.1[more]
SMESG000077911.19.148e-5536.39SMESG000077911.1[more]
SMESG000001877.19.080e-4036.62SMESG000001877.1[more]
SMESG000001954.19.080e-4036.62SMESG000001954.1[more]
SMESG000005296.15.863e-3931.09SMESG000005296.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30000511 ID=SMED30000511|Name=G_PROTEIN_RECEP_F1_2 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1527bp
CTGTTTAAGAATAAATCTACCAAAATCTTTTTTCCTGCTATGAAAAAAAC
TTTAAACAGGTATAAATTTTATTCTGTATTTTCTCTAAATATTGTTTATT
GTTGTTTGTTTGTGTCATAAATATTCCATTATTTAAATTTTTTTTGATAC
CCGATTTAAGTGTGATTATTTTAATTGTTTTAATTAAAATCAATTCAATG
TTTTCAAAATTCGGAGACAAATGCTCCAGTTATTCCTCAGTAAAATTGCT
AGATGATTTTCAGAAAAGTCTTCAGTCTGAAAATACTCTCAAAAGCATTT
GCTTGCCAGTACCTCAGTATGACCTAAAAAGTCTACAGTATTTGTTGGTC
TATAAAATATCGCCCTATGTTATTTTTATAACAGCCTGTACAAATACACT
TGTTTGTATTGTGCTAAGTAGACCAACAATGATAACTCCGACTAATATCA
TTTTGCTTGCCATTGCCGTAACCGATATGCTGACAGGCCTATTTCCCCTT
CCCATATATATAATGCATTATGGGATGAGCAACTCAACTTTGTTTACCGA
AAATATTTTGTTTGCCTATTTTGGGTTTAATCTGTTGACAATATTTCCCA
CAACATTCCATACAGCTTCGGTATGGCTAACAATTACTCTGGCTTTTCAA
AGGGTGATTTACGTAAAGTTTACGACATTTGTCACGAAACTGTGCACAAA
TCGGATCTCAATAATCACCAGTTCACTGATATTCATTCTTGCATTTCTTA
TGCATTCTGTAAACTTTACATACTCATTTGAAAAGTACTATCAAATTTGC
GTCGACAATCAAACGATGTATCTTCCGGAAACCGACAAACTGTCCAATTC
GGAATGGAGAAACTTTTCGAATTTAGGACAAATAATGAAATGCAGCCATT
TCAGTGAATCGGTTTTGTTCTGGTACGCCTCGTTGAGAATTGTATTTTTG
CATGTTGTTCCTTGTATATTGTTGACGATTCTTACTGTGACACTTTTGAT
TGTGCTGAAACAGAAATCGAATCTTTCAAAAAGATTAATGGCTTCAAAGA
ACAATCGTAAACTCTCTACCACCGATGACAAAATTGAGCTGAGCATTTAT
CGTAAATCGAAAAACACTTCGGATCATATTCTGGCAAAAAGCAGATGCAG
TAAAGATTCGTCGAGCTCGACTTCAAAAATGCTTGTAGTTGTTCTTTTGG
TTTTTATCTGCGTCGAAATTCCGATGGGCACAGTAATGACGCTTTATGTT
ATTTTAAAGTATATAGATCGGATTAAAATTTCAAGGAATTGGTCGGAAAT
AACCAACATATGTAACTTTATCATTTTAATATCGTATCCCTTCAATTTCG
TCATATATTGTATCATGTCGAAAAAGTTTCGTGACACATTCAAAGAAACA
CTCTGTCCAAATAGAATTTATAATATTATTTCGAATTCAAATATTGAGTG
ATAATTAATTATAAACATTAATTATAATTGATTATAATTTAGTTCAACGT
GTATTTGTTTATTTTTGTAATGATTGT
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protein sequence of SMED30000511-orf-1

>SMED30000511-orf-1 ID=SMED30000511-orf-1|Name=SMED30000511-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=418bp
MFSKFGDKCSSYSSVKLLDDFQKSLQSENTLKSICLPVPQYDLKSLQYLL
VYKISPYVIFITACTNTLVCIVLSRPTMITPTNIILLAIAVTDMLTGLFP
LPIYIMHYGMSNSTLFTENILFAYFGFNLLTIFPTTFHTASVWLTITLAF
QRVIYVKFTTFVTKLCTNRISIITSSLIFILAFLMHSVNFTYSFEKYYQI
CVDNQTMYLPETDKLSNSEWRNFSNLGQIMKCSHFSESVLFWYASLRIVF
LHVVPCILLTILTVTLLIVLKQKSNLSKRLMASKNNRKLSTTDDKIELSI
YRKSKNTSDHILAKSRCSKDSSSSTSKMLVVVLLVFICVEIPMGTVMTLY
VILKYIDRIKISRNWSEITNICNFIILISYPFNFVIYCIMSKKFRDTFKE
TLCPNRIYNIISNSNIE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000140anterior region of the whole animal
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR0194277TM_GPCR_serpentine_rcpt_Srw
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO:0008528G-protein coupled peptide receptor activity
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 369..395
score: 23.22
coord: 50..74
score: 18.76
coord: 82..103
score: 28.12
coord: 325..349
score: 22.77
coord: 134..156
score: 19.16
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 40..407
e-value: 3.3E-42
score: 146.5
NoneNo IPR availablePANTHERPTHR47023FAMILY NOT NAMEDcoord: 21..412
NoneNo IPR availablePANTHERPTHR47023:SF1SEX PEPTIDE RECEPTORcoord: 21..412
NoneNo IPR availableCDDcd149787tmA_FMRFamide_R-likecoord: 54..398
e-value: 4.91145E-34
score: 126.594
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 48..406
NoneNo IPR availableTMHMMTMhelixcoord: 85..107
NoneNo IPR availableTMHMMTMhelixcoord: 367..389
NoneNo IPR availableTMHMMTMhelixcoord: 122..144
NoneNo IPR availableTMHMMTMhelixcoord: 330..352
NoneNo IPR availableTMHMMTMhelixcoord: 54..73
NoneNo IPR availableTMHMMTMhelixcoord: 248..270
NoneNo IPR availableTMHMMTMhelixcoord: 165..187
IPR0194277TM GPCR, serpentine receptor class w (Srw)PFAMPF103247TM_GPCR_Srwcoord: 305..403
e-value: 1.1E-9
score: 38.1
coord: 54..292
e-value: 1.9E-17
score: 63.6
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 65..387
score: 20.833