Double C2-like domain-containing protein beta
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30000488 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11Note: Hover over icons to view figure legend
Homology
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Human
Match: DOC2B (double C2 domain beta [Source:HGNC Symbol;Acc:HGNC:2986]) HSP 1 Score: 234.572 bits (597), Expect = 1.834e-69 Identity = 132/280 (47.14%), Postives = 174/280 (62.14%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L++ + +D + L TI K LK MD NGL+DPYVK HLLPG + KLRTKT TLNP WNE L Y+GI DM KTLR++V DED ++IGE R+ L L + FS L ++ P+ K D ++ ERG+ILISL ++ + + V IVRC LA MD NG+SDP+ K YL+PD + +K KT KK TLNP FNEEF E+ G +K+LE++VWDYD G +NDFIG V AKG+R K W N +K+ + W L +++
Sbjct: 127 LGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQLPVDKTEDKSLE-ERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTSEL 405
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Human
Match: DOC2B (double C2 domain beta [Source:HGNC Symbol;Acc:HGNC:2986]) HSP 1 Score: 234.572 bits (597), Expect = 2.353e-69 Identity = 132/280 (47.14%), Postives = 174/280 (62.14%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L++ + +D + L TI K LK MD NGL+DPYVK HLLPG + KLRTKT TLNP WNE L Y+GI DM KTLR++V DED ++IGE R+ L L + FS L ++ P+ K D ++ ERG+ILISL ++ + + V IVRC LA MD NG+SDP+ K YL+PD + +K KT KK TLNP FNEEF E+ G +K+LE++VWDYD G +NDFIG V AKG+R K W N +K+ + W L +++
Sbjct: 127 LGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQLPVDKTEDKSLE-ERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTSEL 405
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Human
Match: RPH3A (rabphilin 3A [Source:HGNC Symbol;Acc:HGNC:17056]) HSP 1 Score: 230.72 bits (587), Expect = 1.106e-65 Identity = 134/293 (45.73%), Postives = 174/293 (59.39%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDN------------DDLVDH-----ERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + +D S L TI K LK MD NGL+DPYVK HLLPG + KLRTKT T NPIWNE LVYHGI DM KTLR++V DED G ++IGE R L L ++ NF+ L + P+ + ++ V+ ERGKIL+SL+++ + + V I+RC LA MD NG+SDPF K++LKPD + K KTQ KK TLNP FNEEF ++ +K+L+ISVWDYD G +ND+IG + AKG+R K W N +KK + W L
Sbjct: 344 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQL 636
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Human
Match: RPH3A (rabphilin 3A [Source:HGNC Symbol;Acc:HGNC:17056]) HSP 1 Score: 231.491 bits (589), Expect = 1.771e-65 Identity = 134/293 (45.73%), Postives = 174/293 (59.39%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDN------------DDLVDH-----ERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + +D S L TI K LK MD NGL+DPYVK HLLPG + KLRTKT T NPIWNE LVYHGI DM KTLR++V DED G ++IGE R L L ++ NF+ L + P+ + ++ V+ ERGKIL+SL+++ + + V I+RC LA MD NG+SDPF K++LKPD + K KTQ KK TLNP FNEEF ++ +K+L+ISVWDYD G +ND+IG + AKG+R K W N +KK + W L
Sbjct: 393 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQL 685 HSP 2 Score: 82.8037 bits (203), Expect = 1.146e-15 Identity = 53/189 (28.04%), Postives = 86/189 (45.50%), Query Frame = 1
Query: 319 DRWICPNDRQLAL--RAKLGTGWSVFT--HKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLP 873
+RW+ P+DR L + +L GWSV + ++ EE + I+ V+ R + +++E+ERIG +V L+N+++N + C +CG + ++ C+ C K C C + NN L S + +CK C E RE+WKRSGAW + P+ LP
Sbjct: 11 NRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACV--VCEDCKKNVCTKCGVET-----------------------------NNRLHS-VWLCKICIEQREVWKRSGAWFFKGFPKQVLP 167
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Human
Match: RPH3A (rabphilin 3A [Source:HGNC Symbol;Acc:HGNC:17056]) HSP 1 Score: 231.491 bits (589), Expect = 1.771e-65 Identity = 134/293 (45.73%), Postives = 174/293 (59.39%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDN------------DDLVDH-----ERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + +D S L TI K LK MD NGL+DPYVK HLLPG + KLRTKT T NPIWNE LVYHGI DM KTLR++V DED G ++IGE R L L ++ NF+ L + P+ + ++ V+ ERGKIL+SL+++ + + V I+RC LA MD NG+SDPF K++LKPD + K KTQ KK TLNP FNEEF ++ +K+L+ISVWDYD G +ND+IG + AKG+R K W N +KK + W L
Sbjct: 393 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQL 685 HSP 2 Score: 82.8037 bits (203), Expect = 1.146e-15 Identity = 53/189 (28.04%), Postives = 86/189 (45.50%), Query Frame = 1
Query: 319 DRWICPNDRQLAL--RAKLGTGWSVFT--HKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLP 873
+RW+ P+DR L + +L GWSV + ++ EE + I+ V+ R + +++E+ERIG +V L+N+++N + C +CG + ++ C+ C K C C + NN L S + +CK C E RE+WKRSGAW + P+ LP
Sbjct: 11 NRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACV--VCEDCKKNVCTKCGVET-----------------------------NNRLHS-VWLCKICIEQREVWKRSGAWFFKGFPKQVLP 167
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Celegans
Match: rbf-1 (Rabphilin-1 [Source:UniProtKB/Swiss-Prot;Acc:P41885]) HSP 1 Score: 208.379 bits (529), Expect = 1.821e-56 Identity = 114/279 (40.86%), Postives = 164/279 (58.78%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCAD 2130
+LG + + + SA +L + + K+LK+MD NG SDPYVK HLLPG T TKL +KT +TLNP WNE++ Y+GI D + K LR+ VLD D IG D++GE R+ L LN +E F+ L P+ + + + +RGKI + L +N + ++ + I RC EL MD GFSDP+CK+ L P + + KT TKK TLNP +NE+ + +KTL+I V+D+D G +D+IG + AK +RG+ W +NP + W L D
Sbjct: 683 SLGSITLTLTYHSADKKLKMHLIRAKNLKAMDSNGFSDPYVKFHLLPGNTKATKLTSKTIEKTLNPEWNEEMSYYGITEDDKEKKILRVTVLDRDRIGSDFLGETRIALKKLNDNEMKKFNLYLESALPVPQQTKEEENEDRGKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFVVPFKDLPKKTLQIGVYDHDLGKHDDYIGGILLSTSAKDERGRQWIKCIENPGTLVEAWHRLELD 961 HSP 2 Score: 97.0561 bits (240), Expect = 1.951e-20 Identity = 63/220 (28.64%), Postives = 97/220 (44.09%), Query Frame = 1
Query: 319 DRWICPNDRQLALRAKLGTGWSVFTHKSHFDHES-----NISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREI-WKRSGAWKIQQLPEFCLP----------TTNNVCPHPDSCSKVILNT 930
++W+CP+DR L LRA+L +GWSV T + S +I+ E +HI VL + + E++RIG MV L+ ++R + C +C F L ++ C C K C ++NC + G + +CK C E RE+ WK+SGAW +++PEF P TTN P+ S + + T
Sbjct: 20 NKWVCPSDRHLHLRAQLKSGWSVRTATARSPTNSKAQTGSITAAEQEHIQKVLAKAEESKSKEQQRIGKMVDRLEKMRRRATGNGVTHCLLCHTEFGLLASKSYAAMCVDCRKYVC------------QRNCGVETTDVNQ-----------TTGKVETVFLCKICSEAREVLWKKSGAWFYKEMPEFQRPDDRLPYYVPVTTNGTLPNASSAATPLSGT 216 HSP 3 Score: 56.9954 bits (136), Expect = 4.228e-8 Identity = 38/106 (35.85%), Postives = 56/106 (52.83%), Query Frame = 1
Query: 1291 DNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF--DWIG 1602
++ G +N + ++ L I I +L MD G SDPY K L P + + +T T RTLNP WNE+L + + D+ KTL++ V D D +G D+IG
Sbjct: 822 EDRGKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFV-VPFKDLPKKTLQIGVYDHD-LGKHDDYIG 925
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Celegans
Match: rbf-1 (Rabphilin-1 [Source:UniProtKB/Swiss-Prot;Acc:P41885]) HSP 1 Score: 207.994 bits (528), Expect = 1.994e-56 Identity = 114/279 (40.86%), Postives = 164/279 (58.78%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCAD 2130
+LG + + + SA +L + + K+LK+MD NG SDPYVK HLLPG T TKL +KT +TLNP WNE++ Y+GI D + K LR+ VLD D IG D++GE R+ L LN +E F+ L P+ + + + +RGKI + L +N + ++ + I RC EL MD GFSDP+CK+ L P + + KT TKK TLNP +NE+ + +KTL+I V+D+D G +D+IG + AK +RG+ W +NP + W L D
Sbjct: 674 SLGSITLTLTYHSADKKLKMHLIRAKNLKAMDSNGFSDPYVKFHLLPGNTKATKLTSKTIEKTLNPEWNEEMSYYGITEDDKEKKILRVTVLDRDRIGSDFLGETRIALKKLNDNEMKKFNLYLESALPVPQQTKEEENEDRGKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFVVPFKDLPKKTLQIGVYDHDLGKHDDYIGGILLSTSAKDERGRQWIKCIENPGTLVEAWHRLELD 952 HSP 2 Score: 96.6709 bits (239), Expect = 2.206e-20 Identity = 63/220 (28.64%), Postives = 97/220 (44.09%), Query Frame = 1
Query: 319 DRWICPNDRQLALRAKLGTGWSVFTHKSHFDHES-----NISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREI-WKRSGAWKIQQLPEFCLP----------TTNNVCPHPDSCSKVILNT 930
++W+CP+DR L LRA+L +GWSV T + S +I+ E +HI VL + + E++RIG MV L+ ++R + C +C F L ++ C C K C ++NC + G + +CK C E RE+ WK+SGAW +++PEF P TTN P+ S + + T
Sbjct: 11 NKWVCPSDRHLHLRAQLKSGWSVRTATARSPTNSKAQTGSITAAEQEHIQKVLAKAEESKSKEQQRIGKMVDRLEKMRRRATGNGVTHCLLCHTEFGLLASKSYAAMCVDCRKYVC------------QRNCGVETTDVNQ-----------TTGKVETVFLCKICSEAREVLWKKSGAWFYKEMPEFQRPDDRLPYYVPVTTNGTLPNASSAATPLSGT 207 HSP 3 Score: 56.9954 bits (136), Expect = 4.437e-8 Identity = 38/106 (35.85%), Postives = 56/106 (52.83%), Query Frame = 1
Query: 1291 DNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF--DWIG 1602
++ G +N + ++ L I I +L MD G SDPY K L P + + +T T RTLNP WNE+L + + D+ KTL++ V D D +G D+IG
Sbjct: 813 EDRGKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFV-VPFKDLPKKTLQIGVYDHD-LGKHDDYIG 916
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Celegans
Match: rbf-1 (Rabphilin-1 [Source:UniProtKB/Swiss-Prot;Acc:P41885]) HSP 1 Score: 207.994 bits (528), Expect = 1.994e-56 Identity = 114/279 (40.86%), Postives = 164/279 (58.78%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCAD 2130
+LG + + + SA +L + + K+LK+MD NG SDPYVK HLLPG T TKL +KT +TLNP WNE++ Y+GI D + K LR+ VLD D IG D++GE R+ L LN +E F+ L P+ + + + +RGKI + L +N + ++ + I RC EL MD GFSDP+CK+ L P + + KT TKK TLNP +NE+ + +KTL+I V+D+D G +D+IG + AK +RG+ W +NP + W L D
Sbjct: 674 SLGSITLTLTYHSADKKLKMHLIRAKNLKAMDSNGFSDPYVKFHLLPGNTKATKLTSKTIEKTLNPEWNEEMSYYGITEDDKEKKILRVTVLDRDRIGSDFLGETRIALKKLNDNEMKKFNLYLESALPVPQQTKEEENEDRGKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFVVPFKDLPKKTLQIGVYDHDLGKHDDYIGGILLSTSAKDERGRQWIKCIENPGTLVEAWHRLELD 952 HSP 2 Score: 96.6709 bits (239), Expect = 2.206e-20 Identity = 63/220 (28.64%), Postives = 97/220 (44.09%), Query Frame = 1
Query: 319 DRWICPNDRQLALRAKLGTGWSVFTHKSHFDHES-----NISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREI-WKRSGAWKIQQLPEFCLP----------TTNNVCPHPDSCSKVILNT 930
++W+CP+DR L LRA+L +GWSV T + S +I+ E +HI VL + + E++RIG MV L+ ++R + C +C F L ++ C C K C ++NC + G + +CK C E RE+ WK+SGAW +++PEF P TTN P+ S + + T
Sbjct: 11 NKWVCPSDRHLHLRAQLKSGWSVRTATARSPTNSKAQTGSITAAEQEHIQKVLAKAEESKSKEQQRIGKMVDRLEKMRRRATGNGVTHCLLCHTEFGLLASKSYAAMCVDCRKYVC------------QRNCGVETTDVNQ-----------TTGKVETVFLCKICSEAREVLWKKSGAWFYKEMPEFQRPDDRLPYYVPVTTNGTLPNASSAATPLSGT 207 HSP 3 Score: 56.9954 bits (136), Expect = 4.437e-8 Identity = 38/106 (35.85%), Postives = 56/106 (52.83%), Query Frame = 1
Query: 1291 DNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF--DWIG 1602
++ G +N + ++ L I I +L MD G SDPY K L P + + +T T RTLNP WNE+L + + D+ KTL++ V D D +G D+IG
Sbjct: 813 EDRGKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFV-VPFKDLPKKTLQIGVYDHD-LGKHDDYIG 916
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Celegans
Match: rbf-1 (Rabphilin-1 [Source:UniProtKB/Swiss-Prot;Acc:P41885]) HSP 1 Score: 208.379 bits (529), Expect = 2.656e-56 Identity = 114/279 (40.86%), Postives = 164/279 (58.78%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCAD 2130
+LG + + + SA +L + + K+LK+MD NG SDPYVK HLLPG T TKL +KT +TLNP WNE++ Y+GI D + K LR+ VLD D IG D++GE R+ L LN +E F+ L P+ + + + +RGKI + L +N + ++ + I RC EL MD GFSDP+CK+ L P + + KT TKK TLNP +NE+ + +KTL+I V+D+D G +D+IG + AK +RG+ W +NP + W L D
Sbjct: 749 SLGSITLTLTYHSADKKLKMHLIRAKNLKAMDSNGFSDPYVKFHLLPGNTKATKLTSKTIEKTLNPEWNEEMSYYGITEDDKEKKILRVTVLDRDRIGSDFLGETRIALKKLNDNEMKKFNLYLESALPVPQQTKEEENEDRGKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFVVPFKDLPKKTLQIGVYDHDLGKHDDYIGGILLSTSAKDERGRQWIKCIENPGTLVEAWHRLELD 1027 HSP 2 Score: 97.0561 bits (240), Expect = 2.092e-20 Identity = 63/220 (28.64%), Postives = 97/220 (44.09%), Query Frame = 1
Query: 319 DRWICPNDRQLALRAKLGTGWSVFTHKSHFDHES-----NISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREI-WKRSGAWKIQQLPEFCLP----------TTNNVCPHPDSCSKVILNT 930
++W+CP+DR L LRA+L +GWSV T + S +I+ E +HI VL + + E++RIG MV L+ ++R + C +C F L ++ C C K C ++NC + G + +CK C E RE+ WK+SGAW +++PEF P TTN P+ S + + T
Sbjct: 86 NKWVCPSDRHLHLRAQLKSGWSVRTATARSPTNSKAQTGSITAAEQEHIQKVLAKAEESKSKEQQRIGKMVDRLEKMRRRATGNGVTHCLLCHTEFGLLASKSYAAMCVDCRKYVC------------QRNCGVETTDVNQ-----------TTGKVETVFLCKICSEAREVLWKKSGAWFYKEMPEFQRPDDRLPYYVPVTTNGTLPNASSAATPLSGT 282 HSP 3 Score: 56.9954 bits (136), Expect = 4.459e-8 Identity = 38/106 (35.85%), Postives = 56/106 (52.83%), Query Frame = 1
Query: 1291 DNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF--DWIG 1602
++ G +N + ++ L I I +L MD G SDPY K L P + + +T T RTLNP WNE+L + + D+ KTL++ V D D +G D+IG
Sbjct: 888 EDRGKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFV-VPFKDLPKKTLQIGVYDHD-LGKHDDYIG 991
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Celegans
Match: rbf-1 (Rabphilin-1 [Source:UniProtKB/Swiss-Prot;Acc:P41885]) HSP 1 Score: 208.379 bits (529), Expect = 3.124e-56 Identity = 114/279 (40.86%), Postives = 164/279 (58.78%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCAD 2130
+LG + + + SA +L + + K+LK+MD NG SDPYVK HLLPG T TKL +KT +TLNP WNE++ Y+GI D + K LR+ VLD D IG D++GE R+ L LN +E F+ L P+ + + + +RGKI + L +N + ++ + I RC EL MD GFSDP+CK+ L P + + KT TKK TLNP +NE+ + +KTL+I V+D+D G +D+IG + AK +RG+ W +NP + W L D
Sbjct: 827 SLGSITLTLTYHSADKKLKMHLIRAKNLKAMDSNGFSDPYVKFHLLPGNTKATKLTSKTIEKTLNPEWNEEMSYYGITEDDKEKKILRVTVLDRDRIGSDFLGETRIALKKLNDNEMKKFNLYLESALPVPQQTKEEENEDRGKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFVVPFKDLPKKTLQIGVYDHDLGKHDDYIGGILLSTSAKDERGRQWIKCIENPGTLVEAWHRLELD 1105 HSP 2 Score: 96.6709 bits (239), Expect = 2.853e-20 Identity = 63/220 (28.64%), Postives = 97/220 (44.09%), Query Frame = 1
Query: 319 DRWICPNDRQLALRAKLGTGWSVFTHKSHFDHES-----NISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREI-WKRSGAWKIQQLPEFCLP----------TTNNVCPHPDSCSKVILNT 930
++W+CP+DR L LRA+L +GWSV T + S +I+ E +HI VL + + E++RIG MV L+ ++R + C +C F L ++ C C K C ++NC + G + +CK C E RE+ WK+SGAW +++PEF P TTN P+ S + + T
Sbjct: 164 NKWVCPSDRHLHLRAQLKSGWSVRTATARSPTNSKAQTGSITAAEQEHIQKVLAKAEESKSKEQQRIGKMVDRLEKMRRRATGNGVTHCLLCHTEFGLLASKSYAAMCVDCRKYVC------------QRNCGVETTDVNQ-----------TTGKVETVFLCKICSEAREVLWKKSGAWFYKEMPEFQRPDDRLPYYVPVTTNGTLPNASSAATPLSGT 360 HSP 3 Score: 56.9954 bits (136), Expect = 4.866e-8 Identity = 38/106 (35.85%), Postives = 56/106 (52.83%), Query Frame = 1
Query: 1291 DNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF--DWIG 1602
++ G +N + ++ L I I +L MD G SDPY K L P + + +T T RTLNP WNE+L + + D+ KTL++ V D D +G D+IG
Sbjct: 966 EDRGKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFV-VPFKDLPKKTLQIGVYDHD-LGKHDDYIG 1069
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Fly
Match: Rph (gene:FBgn0030230 transcript:FBtr0301558) HSP 1 Score: 155.606 bits (392), Expect = 4.319e-41 Identity = 95/281 (33.81%), Postives = 148/281 (52.67%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLR---TKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCAD 2130
LG L I + A L T+ +DL +MD GL+DPY K +++ + H R TKT ++T NP +NE L + G+ ++ + + +A+ D+D G D++G ++ L ++S +Y S L + + + GK+L+SL +N K + V + +C L MD NG SDPF KI LKPD + K KT K TLNP +NEEF E ++ L ++VWD D G +NDF+G ++ ++KG+R + W P+ + W L D
Sbjct: 117 LGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYGHDFLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPNGKMLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCLAPD 397
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Fly
Match: Rph (gene:FBgn0030230 transcript:FBtr0332296) HSP 1 Score: 155.606 bits (392), Expect = 4.319e-41 Identity = 95/281 (33.81%), Postives = 148/281 (52.67%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLR---TKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCAD 2130
LG L I + A L T+ +DL +MD GL+DPY K +++ + H R TKT ++T NP +NE L + G+ ++ + + +A+ D+D G D++G ++ L ++S +Y S L + + + GK+L+SL +N K + V + +C L MD NG SDPF KI LKPD + K KT K TLNP +NEEF E ++ L ++VWD D G +NDF+G ++ ++KG+R + W P+ + W L D
Sbjct: 117 LGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYGHDFLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPNGKMLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCLAPD 397
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Fly
Match: Rph (gene:FBgn0030230 transcript:FBtr0071502) HSP 1 Score: 157.147 bits (396), Expect = 4.548e-40 Identity = 97/282 (34.40%), Postives = 150/282 (53.19%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKL----RTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCAD 2130
LG L I + A L T+ +DL +MD GL+DPY K +++ + H TK RTKT ++T NP +NE L + G+ ++ + + +A+ D+D G D++G ++ L ++S +Y S L + + + GK+L+SL +N K + V + +C L MD NG SDPF KI LKPD + K KT K TLNP +NEEF E ++ L ++VWD D G +NDF+G ++ ++KG+R + W P+ + W L D
Sbjct: 354 LGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLNIITPEAH-TKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYGHDFLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPNGKMLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCLAPD 634 HSP 2 Score: 98.9821 bits (245), Expect = 3.451e-21 Identity = 55/195 (28.21%), Postives = 99/195 (50.77%), Query Frame = 1
Query: 319 DRWICPNDRQLALRAKLGTGWSVFTHKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPTTNNVCPHPD 903
++++CP+DRQLALRAKL GWS + K+ + PEE + I V++R + + E++R+G +V ++ IK++ + C +CG +F + + C+ C ++ C C ++ I + + I +C+ C ETRE+WK+SGAW + LP++ +P + + P P+
Sbjct: 11 NKFVCPSDRQLALRAKLKAGWS--SSKT----SEPLRPEEQEAIISVIRRNEEIEVAERQRVGRLVERVEKIKQHAVERGPNCCRLCGDTFGILRPQ--RILCEDCRQSVCTKCSVDIN------------------------IRYHTSERSREIWLCRICSETREMWKKSGAWFFKGLPKYDMPRSASATPIPN 173
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Fly
Match: Syt7 (gene:FBgn0039900 transcript:FBtr0089139) HSP 1 Score: 123.635 bits (309), Expect = 5.923e-31 Identity = 91/280 (32.50%), Postives = 144/280 (51.43%), Query Frame = 1
Query: 1291 DNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFR--AKGDRGKLWKAVYDNPNKKFDGWFIL 2121
+N+G +++ + +D + L++ + GK+L + D++G SDPYV+ LLP K H +L TK RTLNP WNE + G + S+ L L V D D D IGE L L ++ + +F L +P AKD + G++L SL ++ NS + +T+++ L D NG SDP+ K++L+ R+ KRKT TLNP FNE F + +E +L++ V D+D N+ IG + + + K W+ + P + W L
Sbjct: 13 ENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKH--RLETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQVDFAGKQSFWKAL---KPPAKD-------KCGELLSSLCYHPSNSILTLTLIKARNLKAKDINGKSDPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFSFNVPWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNGSGASETKHWQDMISKPRQTVVQWHRL 280
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Fly
Match: Syt7 (gene:FBgn0039900 transcript:FBtr0343990) HSP 1 Score: 122.865 bits (307), Expect = 1.036e-29 Identity = 91/280 (32.50%), Postives = 144/280 (51.43%), Query Frame = 1
Query: 1291 DNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFR--AKGDRGKLWKAVYDNPNKKFDGWFIL 2121
+N+G +++ + +D + L++ + GK+L + D++G SDPYV+ LLP K H +L TK RTLNP WNE + G + S+ L L V D D D IGE L L ++ + +F L +P AKD + G++L SL ++ NS + +T+++ L D NG SDP+ K++L+ R+ KRKT TLNP FNE F + +E +L++ V D+D N+ IG + + + K W+ + P + W L
Sbjct: 146 ENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKH--RLETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQVDFAGKQSFWKAL---KPPAKD-------KCGELLSSLCYHPSNSILTLTLIKARNLKAKDINGKSDPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFSFNVPWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNGSGASETKHWQDMISKPRQTVVQWHRL 413
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Zebrafish
Match: doc2d (double C2-like domains, delta [Source:ZFIN;Acc:ZDB-GENE-081104-451]) HSP 1 Score: 236.113 bits (601), Expect = 5.164e-70 Identity = 136/283 (48.06%), Postives = 171/283 (60.42%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVD-------HERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + D + L TI K LK+MD NGL+DPYVK HLLPG + KLRTKT TLNP+WNE L+YHGI DM +KTLRL V D D +G ++IGE R+ L L E ++ L + + N +D ERG+IL+SLL+N + +T+ V I+RC LA MD NG+SDPF KI L+PD + +K KT KK TLNP FNEEF ++ +KTLEISVWDYD G +NDFIG V+ AKGDR K W KK + W L
Sbjct: 138 LGTLEFNLLFDQENNCLHCTIHKAKGLKAMDSNGLADPYVKLHLLPGASKANKLRTKTLKNTLNPVWNETLIYHGITAADMTTKTLRLCVCDMDRLGRNEFIGEVRVALKKLKEGESKKYNMGLERIAQTREGNSQAMDPAAPVAEEERGRILVSLLYNTEKNTLVVGIIRCAHLAAMDSNGYSDPFVKIILQPDMGKKSKYKTTVKKKTLNPEFNEEFSYDVPHDQLAKKTLEISVWDYDLGMSNDFIGGVELGINAKGDRLKHWFECLKYKGKKVEYWHTL 420
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Zebrafish
Match: doc2b (double C2-like domains, beta [Source:ZFIN;Acc:ZDB-GENE-090615-1]) HSP 1 Score: 241.121 bits (614), Expect = 9.725e-70 Identity = 135/280 (48.21%), Postives = 178/280 (63.57%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L++ + +D + L TI K LK MD NGLSDPYVK HLLPG + KLRTKT TLNP+W+E L Y+GI DM KTLR++V DED ++IGE R+ L L ++ NFS+ L ++ PI K +D ++ ERG+I+ISL ++ + S + V I+RC LA MD NGFSDP+ K YLKPD+ + +K KT KK TLNP FNEEF E+ +KTLE++VWDYD G +NDFIG V A G+R K W N +KK + W L ++
Sbjct: 355 LGTLDFSLLYDQENNALHCTINKAKGLKPMDHNGLSDPYVKLHLLPGASKANKLRTKTLRNTLNPVWSETLTYYGITDEDMVRKTLRISVCDEDKFRHNEFIGETRIPLKKLKPNQTKNFSNCLEKQLPIDKTDDKSLE-ERGRIMISLKYSSQKSGLVVGIIRCAHLAAMDANGFSDPYVKTYLKPDENKKSKHKTAVKKKTLNPEFNEEFFYEIKYADLSKKTLEVTVWDYDIGKSNDFIGGVSLGINASGERLKHWFDCLKNKDKKIERWHTLTNEL 633 HSP 2 Score: 101.293 bits (251), Expect = 9.683e-22 Identity = 61/191 (31.94%), Postives = 87/191 (45.55%), Query Frame = 1
Query: 319 DRWICPNDRQLALRAKLGTGWSVFTHKSHFDHESN-ISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPTTNNV 888
++W+CPNDRQL LRAKL TGWS+ T +S ++ + EL I V+ R + + IE+ RIG +V L N++ + +C +CG F L +S C C C C I G K +CK C E RE+WKRSGAW + LP+ P +++
Sbjct: 11 EQWVCPNDRQLMLRAKLHTGWSIHTFQSERQRKAQALEKRELDLIMSVIHRAEQLELIEQHRIGRLVERLDNMRSSAMGNGLSQCLLCGEVFGLLGSS--SVLCLDCCMKVCTKCG----------------------------IETTAGGQKRTQWLCKICSEQREVWKRSGAWFYKALPKHIRPIKDSI 171
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Zebrafish
Match: rph3ab (rabphilin 3A homolog (mouse), b [Source:ZFIN;Acc:ZDB-GENE-090706-3]) HSP 1 Score: 233.417 bits (594), Expect = 2.165e-67 Identity = 138/290 (47.59%), Postives = 171/290 (58.97%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNL-----LQRQPIA---------KDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + +D S L I K LK MD NGL+DPYVK HLLPG + TKLRTKT T NP WNE LVYHG+ DM KTLRL+V DED G ++IGE R+ L L +++ NF+ L +R A +D D ERG+ILISL+++ + + V +VRC LA MD NG+SDPF KI LKPD + K KTQ KK TLNP FNEEF E+ +KTL+ISVWDYD G ND+IG + AKG+R K W N +KK + W L
Sbjct: 279 LGSLEFTLLYDQGNSSLHCNIIKAKGLKPMDSNGLADPYVKLHLLPGASKSTKLRTKTLRNTRNPTWNETLVYHGLTDEDMQRKTLRLSVCDEDKFGHNEFIGETRVALKKLKINQKKNFNICLERVVQTKRSSTAGGARGITLYEDEDGSELEERGRILISLMYSTQLGRLIVGVVRCVHLAAMDANGYSDPFVKICLKPDMGKKAKNKTQIKKKTLNPEFNEEFSYEIKHAELAKKTLDISVWDYDIGKCNDYIGGCQLGITAKGERLKHWYECLKNKDKKIERWHTL 568 HSP 2 Score: 63.1586 bits (152), Expect = 7.289e-10 Identity = 42/153 (27.45%), Postives = 63/153 (41.18%), Query Frame = 1
Query: 418 SNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPT 876
+ ++ EE + I+ V+ R + + +E+ERIG +V L N+K+ C +CG L C+ C K C C Q N + +CK C E RE+WKRSGAW + LP+ LP+
Sbjct: 38 AELTDEEKEIINNVIARAEKMEAMEQERIGRLVNRLDNMKKTVCGDGVSRCLLCGEQ--LGGAGDRAVVCEDCKKNMCTKCGVQ------------------------------TNTRPRSVWLCKICSEQREVWKRSGAWFFKGLPKQFLPS 158
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Zebrafish
Match: rph3ab (rabphilin 3A homolog (mouse), b [Source:ZFIN;Acc:ZDB-GENE-090706-3]) HSP 1 Score: 233.032 bits (593), Expect = 2.333e-67 Identity = 138/290 (47.59%), Postives = 171/290 (58.97%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNL-----LQRQPIA---------KDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + +D S L I K LK MD NGL+DPYVK HLLPG + TKLRTKT T NP WNE LVYHG+ DM KTLRL+V DED G ++IGE R+ L L +++ NF+ L +R A +D D ERG+ILISL+++ + + V +VRC LA MD NG+SDPF KI LKPD + K KTQ KK TLNP FNEEF E+ +KTL+ISVWDYD G ND+IG + AKG+R K W N +KK + W L
Sbjct: 266 LGSLEFTLLYDQGNSSLHCNIIKAKGLKPMDSNGLADPYVKLHLLPGASKSTKLRTKTLRNTRNPTWNETLVYHGLTDEDMQRKTLRLSVCDEDKFGHNEFIGETRVALKKLKINQKKNFNICLERVVQTKRSSTAGGARGITLYEDEDGSELEERGRILISLMYSTQLGRLIVGVVRCVHLAAMDANGYSDPFVKICLKPDMGKKAKNKTQIKKKTLNPEFNEEFSYEIKHAELAKKTLDISVWDYDIGKCNDYIGGCQLGITAKGERLKHWYECLKNKDKKIERWHTL 555 HSP 2 Score: 63.1586 bits (152), Expect = 7.673e-10 Identity = 42/153 (27.45%), Postives = 63/153 (41.18%), Query Frame = 1
Query: 418 SNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPT 876
+ ++ EE + I+ V+ R + + +E+ERIG +V L N+K+ C +CG L C+ C K C C Q N + +CK C E RE+WKRSGAW + LP+ LP+
Sbjct: 25 AELTDEEKEIINNVIARAEKMEAMEQERIGRLVNRLDNMKKTVCGDGVSRCLLCGEQ--LGGAGDRAVVCEDCKKNMCTKCGVQ------------------------------TNTRPRSVWLCKICSEQREVWKRSGAWFFKGLPKQFLPS 145
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Zebrafish
Match: doc2b (double C2-like domains, beta [Source:ZFIN;Acc:ZDB-GENE-090615-1]) HSP 1 Score: 234.187 bits (596), Expect = 4.638e-67 Identity = 135/288 (46.88%), Postives = 178/288 (61.81%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGK--------DLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L++ + +D + L TI K LK MD NGLSDPYVK HLLPG + KLRTKT TLNP+W+E L Y+GI DM KTLR++V DED ++IGE R+ L L ++ NFS+ L ++ PI K +D ++ ERG+I+ISL ++ + S + V I+RC LA MD NGFSDP+ K YLKPD+ + +K KT KK TLNP FNEEF E+ +KTLE++VWDYD G +NDFIG V A G+R K W N +KK + W L ++
Sbjct: 355 LGTLDFSLLYDQENNALHCTINKAKLPVPRYKKGLKPMDHNGLSDPYVKLHLLPGASKANKLRTKTLRNTLNPVWSETLTYYGITDEDMVRKTLRISVCDEDKFRHNEFIGETRIPLKKLKPNQTKNFSNCLEKQLPIDKTDDKSLE-ERGRIMISLKYSSQKSGLVVGIIRCAHLAAMDANGFSDPYVKTYLKPDENKKSKHKTAVKKKTLNPEFNEEFFYEIKYADLSKKTLEVTVWDYDIGKSNDFIGGVSLGINASGERLKHWFDCLKNKDKKIERWHTLTNEL 641 HSP 2 Score: 101.679 bits (252), Expect = 8.092e-22 Identity = 61/191 (31.94%), Postives = 87/191 (45.55%), Query Frame = 1
Query: 319 DRWICPNDRQLALRAKLGTGWSVFTHKSHFDHESN-ISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPTTNNV 888
++W+CPNDRQL LRAKL TGWS+ T +S ++ + EL I V+ R + + IE+ RIG +V L N++ + +C +CG F L +S C C C C I G K +CK C E RE+WKRSGAW + LP+ P +++
Sbjct: 11 EQWVCPNDRQLMLRAKLHTGWSIHTFQSERQRKAQALEKRELDLIMSVIHRAEQLELIEQHRIGRLVERLDNMRSSAMGNGLSQCLLCGEVFGLLGSS--SVLCLDCCMKVCTKCG----------------------------IETTAGGQKRTQWLCKICSEQREVWKRSGAWFYKALPKHIRPIKDSI 171
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Xenopus
Match: RPH3A (rabphilin 3A [Source:NCBI gene;Acc:100487950]) HSP 1 Score: 246.514 bits (628), Expect = 2.249e-72 Identity = 173/477 (36.27%), Postives = 244/477 (51.15%), Query Frame = 1
Query: 760 NNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPTTNNVCPHPDSCSKVILNTQVTNIDSASWETYRRPPKWSTMKENREIDINIDENQQVEPAFERFSFNPFEDELKETINKMESSNNISSNPTA---TLQWNNFNEKFKNDADFGTKLYRQNPPEGSLFWXXXXXXXXXXXXXXD---NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAK---------------DNDDLVD-HERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
+N I +CK C E RE+WKRSGAW + P+ LP P P + SK + + + S + +R P+ + + + + QV+ + P L + + S ++ N A T Q + + A + + + P +Q+ +E D LG L + +F+D + L I K LK MD NGL+DPYVK HLLPG + KLRTKT T NPIWNE LVYHGI ++ KTLR++V DED G ++IGE R L L +++ +F+ L + P+ + +ND D ERGKIL+SL++N + + V IVRC LA MD NG+SDPF K++LKPD + K KTQ KK TLNP FNEEF E+ +K L++SVWDYD G +ND+IG + AKG+R K W N +KK + W +L
Sbjct: 79 SNSRPHSIWLCKICSEQREVWKRSGAWFFKGFPKHVLPQ-----PIPVNKSKP---QKPSAVSEDSGQEQKRYPRTQS-RGDYSFTGKLQHILQVKGFVTK---RPCGTTLPASQPESTYSASVPRNEKADSFTPQGVRQDRPLRQAASYTSSVPTVAAPSARQPQTQDEEEEEANSYDSDEATTLGSLEFSLFYDQENNSLHCGIIKAKGLKPMDSNGLADPYVKLHLLPGASKANKLRTKTLRNTRNPIWNETLVYHGITDEELQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQKKSFNVCLERVIPMKRAGTTGSVRGMALYEDENDRGGDVEERGKILVSLMYNTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKNKTQIKKKTLNPEFNEEFFYEIKHSDLAKKQLDVSVWDYDIGKSNDYIGGCQLGINAKGERLKHWYECLKNKDKKIERWHVL 543
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Xenopus
Match: ivns1abp (influenza virus NS1A binding protein [Source:Xenbase;Acc:XB-GENE-949332]) HSP 1 Score: 239.195 bits (609), Expect = 2.111e-71 Identity = 137/280 (48.93%), Postives = 176/280 (62.86%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L++ + +D + L TI K LK MD NGLSDPYVK HLLPG + KLRTKT TLNP WNE L Y+GI DM KTLR++V DED ++IGE R+ L L ++ NFS L ++ PI K D ++ ERG+ILISL ++ + S + V I+RC LA MD NG+SDP+ K YLKPD+ + +K KT KK TLNP FNEEF E+ +KTLE++VWDYD G +NDFIG V AKG+R K W N +KK + W L ++
Sbjct: 109 LGTLDFSLLYDQENNALHCTINKAKGLKPMDHNGLSDPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRIPLKKLKPNQTKNFSICLEKQLPIDKTEDKSLE-ERGRILISLKYSSQKSGLLVGIIRCAHLAAMDANGYSDPYVKTYLKPDEDKKSKHKTAVKKKTLNPEFNEEFCYEIKHSDLAKKTLEVTVWDYDIGKSNDFIGGVVLGINAKGERLKHWFDCLKNKDKKIERWHTLTNEL 387
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Xenopus
Match: RPH3A (rabphilin 3A [Source:NCBI gene;Acc:100487950]) HSP 1 Score: 235.728 bits (600), Expect = 2.228e-70 Identity = 133/276 (48.19%), Postives = 172/276 (62.32%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + +F+D + L I K LK MD NGL+DPYVK HLLPG + KLRTKT T NPIWNE LVYHGI ++ KTLR++V DED G ++IGE R L L +++ +F N+ + I D V+ ERGKIL+SL++N + + V IVRC LA MD NG+SDPF K++LKPD + K KTQ KK TLNP FNEEF E+ +K L++SVWDYD G +ND+IG + AKG+R K W N +KK + W +L
Sbjct: 89 LGSLEFSLFYDQENNSLHCGIIKAKGLKPMDSNGLADPYVKLHLLPGASKANKLRTKTLRNTRNPIWNETLVYHGITDEELQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQKKSF--NVCLERVIPNDRGGDVE-ERGKILVSLMYNTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKNKTQIKKKTLNPEFNEEFFYEIKHSDLAKKQLDVSVWDYDIGKSNDYIGGCQLGINAKGERLKHWYECLKNKDKKIERWHVL 361
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Xenopus
Match: ivns1abp (influenza virus NS1A binding protein [Source:Xenbase;Acc:XB-GENE-949332]) HSP 1 Score: 232.261 bits (591), Expect = 1.188e-68 Identity = 137/288 (47.57%), Postives = 177/288 (61.46%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITI--------CNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L++ + +D + L TI + K LK MD NGLSDPYVK HLLPG + KLRTKT TLNP WNE L Y+GI DM KTLR++V DED ++IGE R+ L L ++ NFS L ++ PI K D ++ ERG+ILISL ++ + S + V I+RC LA MD NG+SDP+ K YLKPD+ + +K KT KK TLNP FNEEF E+ +KTLE++VWDYD G +NDFIG V AKG+R K W N +KK + W L ++
Sbjct: 109 LGTLDFSLLYDQENNALHCTINKAKLPKVIHKKGLKPMDHNGLSDPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRIPLKKLKPNQTKNFSICLEKQLPIDKTEDKSLE-ERGRILISLKYSSQKSGLLVGIIRCAHLAAMDANGYSDPYVKTYLKPDEDKKSKHKTAVKKKTLNPEFNEEFCYEIKHSDLAKKTLEVTVWDYDIGKSNDFIGGVVLGINAKGERLKHWFDCLKNKDKKIERWHTLTNEL 395
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Xenopus
Match: RPH3A (rabphilin 3A [Source:NCBI gene;Acc:100487950]) HSP 1 Score: 232.646 bits (592), Expect = 7.823e-67 Identity = 134/292 (45.89%), Postives = 175/292 (59.93%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAK---------------DNDDLVD-HERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + +F+D + L I K LK MD NGL+DPYVK HLLPG + KLRTKT T NPIWNE LVYHGI ++ KTLR++V DED G ++IGE R L L +++ +F+ L + P+ + +ND D ERGKIL+SL++N + + V IVRC LA MD NG+SDPF K++LKPD + K KTQ KK TLNP FNEEF E+ +K L++SVWDYD G +ND+IG + AKG+R K W N +KK + W +L
Sbjct: 291 LGSLEFSLFYDQENNSLHCGIIKAKGLKPMDSNGLADPYVKLHLLPGASKANKLRTKTLRNTRNPIWNETLVYHGITDEELQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQKKSFNVCLERVIPMKRAGTTGSVRGMALYEDENDRGGDVEERGKILVSLMYNTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKNKTQIKKKTLNPEFNEEFFYEIKHSDLAKKQLDVSVWDYDIGKSNDYIGGCQLGINAKGERLKHWYECLKNKDKKIERWHVL 582 HSP 2 Score: 78.1814 bits (191), Expect = 2.173e-14 Identity = 52/177 (29.38%), Postives = 79/177 (44.63%), Query Frame = 1
Query: 349 LALRAKLGTGWSVF--THKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLP 873
+ALR+KL GWSV + HE ++ EE + I+ V+ R +++E+ERIG +V +L+++++ + C +CG L T C+ C K C C Q +N I +CK C E RE+WKRSGAW + P+ LP
Sbjct: 1 MALRSKLDAGWSVHPNNQERQRKHEE-LTDEEKEIINRVIARAAKMEEMEQERIGRLVDNLEDMRKTVTGDGVNRCILCGEQLGLPGTKCV--VCEDCKKNVCTKCGVQ------------------------------SNSRPHSIWLCKICSEQREVWKRSGAWFFKGFPKHVLP 144
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Mouse
Match: Doc2b (double C2, beta [Source:MGI Symbol;Acc:MGI:1100497]) HSP 1 Score: 233.802 bits (595), Expect = 3.137e-69 Identity = 134/280 (47.86%), Postives = 173/280 (61.79%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L++ + +D + L TI K LK MD NGL+DPYVK HLLPG + KLRTKT TLNP WNE L Y+GI DM KTLR++V DED ++IGE R+ L L + FS L ++ P+ K D ++ ERG+ILISL ++ + + V IVRC LA MD NG+SDP+ K YLKPD + +K KT KK TLNP FNEEF E+ G +KTLE++VWDYD G +NDFIG V AKG+R K W N +K+ + W L ++
Sbjct: 127 LGTLDFSLLYDQENNALHCTISKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPSWNETLTYYGITDEDMVRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQLPVDKAEDKSLE-ERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKTLEVTVWDYDIGKSNDFIGGVVLGINAKGERLKHWFDCLKNKDKRIERWHTLTNEL 405
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Mouse
Match: Rph3a (rabphilin 3A [Source:MGI Symbol;Acc:MGI:102788]) HSP 1 Score: 230.335 bits (586), Expect = 2.400e-65 Identity = 132/293 (45.05%), Postives = 174/293 (59.39%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDN------------DDLVDH-----ERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + +D S L TI K LK MD NGL+DPYVK HLLPG + KLRTKT T NP+WNE L YHGI DM KTLR++V DED G ++IGE R L L +++ NF+ L + P+ + ++ V+ ERGKIL+SL+++ + + V I+RC LA MD NG+SDPF K++LKPD + K KTQ KK TLNP FNEEF ++ +K+L+ISVWDYD G +ND+IG + AKG+R K W N +KK + W L
Sbjct: 380 LGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQL 672 HSP 2 Score: 78.9518 bits (193), Expect = 1.179e-14 Identity = 49/191 (25.65%), Postives = 82/191 (42.93%), Query Frame = 1
Query: 313 IMDRWICPNDRQLAL--RAKLGTGWSVF--THKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLP 873
+++RW+ P D L + +L GWSV + ++ EE + I+ V+ R + + +E+ERIG +V L+ +++N + C +CG + ++ C+ C K C C + S N + +CK C E RE+WKRSGAW + P+ LP
Sbjct: 5 VVNRWMYPGDGPLQSNDKEQLQAGWSVHPGAQTDRQRKQEELTDEEKEIINRVIARAEKMEAMEQERIGRLVDRLETMRKNVAGDGVNRCILCGEQLGMLGSACV--VCEDCKKNVCTKCGVETS-----------------------------NNRPHPVWLCKICLEQREVWKRSGAWFFKGFPKQVLP 164
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Mouse
Match: Rph3a (rabphilin 3A [Source:MGI Symbol;Acc:MGI:102788]) HSP 1 Score: 230.335 bits (586), Expect = 2.400e-65 Identity = 132/293 (45.05%), Postives = 174/293 (59.39%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDN------------DDLVDH-----ERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + +D S L TI K LK MD NGL+DPYVK HLLPG + KLRTKT T NP+WNE L YHGI DM KTLR++V DED G ++IGE R L L +++ NF+ L + P+ + ++ V+ ERGKIL+SL+++ + + V I+RC LA MD NG+SDPF K++LKPD + K KTQ KK TLNP FNEEF ++ +K+L+ISVWDYD G +ND+IG + AKG+R K W N +KK + W L
Sbjct: 380 LGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQL 672 HSP 2 Score: 78.9518 bits (193), Expect = 1.179e-14 Identity = 49/191 (25.65%), Postives = 82/191 (42.93%), Query Frame = 1
Query: 313 IMDRWICPNDRQLAL--RAKLGTGWSVF--THKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLP 873
+++RW+ P D L + +L GWSV + ++ EE + I+ V+ R + + +E+ERIG +V L+ +++N + C +CG + ++ C+ C K C C + S N + +CK C E RE+WKRSGAW + P+ LP
Sbjct: 5 VVNRWMYPGDGPLQSNDKEQLQAGWSVHPGAQTDRQRKQEELTDEEKEIINRVIARAEKMEAMEQERIGRLVDRLETMRKNVAGDGVNRCILCGEQLGMLGSACV--VCEDCKKNVCTKCGVETS-----------------------------NNRPHPVWLCKICLEQREVWKRSGAWFFKGFPKQVLP 164
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Mouse
Match: Rph3a (rabphilin 3A [Source:MGI Symbol;Acc:MGI:102788]) HSP 1 Score: 230.335 bits (586), Expect = 2.400e-65 Identity = 132/293 (45.05%), Postives = 174/293 (59.39%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDN------------DDLVDH-----ERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + +D S L TI K LK MD NGL+DPYVK HLLPG + KLRTKT T NP+WNE L YHGI DM KTLR++V DED G ++IGE R L L +++ NF+ L + P+ + ++ V+ ERGKIL+SL+++ + + V I+RC LA MD NG+SDPF K++LKPD + K KTQ KK TLNP FNEEF ++ +K+L+ISVWDYD G +ND+IG + AKG+R K W N +KK + W L
Sbjct: 380 LGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQL 672 HSP 2 Score: 78.9518 bits (193), Expect = 1.179e-14 Identity = 49/191 (25.65%), Postives = 82/191 (42.93%), Query Frame = 1
Query: 313 IMDRWICPNDRQLAL--RAKLGTGWSVF--THKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLP 873
+++RW+ P D L + +L GWSV + ++ EE + I+ V+ R + + +E+ERIG +V L+ +++N + C +CG + ++ C+ C K C C + S N + +CK C E RE+WKRSGAW + P+ LP
Sbjct: 5 VVNRWMYPGDGPLQSNDKEQLQAGWSVHPGAQTDRQRKQEELTDEEKEIINRVIARAEKMEAMEQERIGRLVDRLETMRKNVAGDGVNRCILCGEQLGMLGSACV--VCEDCKKNVCTKCGVETS-----------------------------NNRPHPVWLCKICLEQREVWKRSGAWFFKGFPKQVLP 164
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Mouse
Match: Doc2a (double C2, alpha [Source:MGI Symbol;Acc:MGI:109446]) HSP 1 Score: 212.231 bits (539), Expect = 2.741e-61 Identity = 124/302 (41.06%), Postives = 171/302 (56.62%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPI----------------------AKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L + + +D A L I K LK MD NGL+DPYVK HLLPG KL+TKT TLNP+WNE+L Y GI D+ K LR++V DED + ++IGE R+ L L ++ +F+ L ++ P+ A+ L++ ERG+IL+SL ++ + + V IVRC LA MD NG+SDP+ K YL+PD + +K KT KK TLNP FNEEF E++ KTLE++VWDYD G +NDFIG V A+G+ K W P+ + W L +++
Sbjct: 95 LGTLEFDLLYDQASCMLHCRILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEELTYSGITDDDITHKVLRISVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLPSPSSMSAALRGISCYLKELEQAEQGPGLLE-ERGRILLSLSYSSRRHGLLVGIVRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEAQKHWNDCLHQPDTALERWHTLTSEL 395
BLAST of Double C2-like domain-containing protein beta vs. UniProt/SwissProt
Match: sp|Q14184|DOC2B_HUMAN (Double C2-like domain-containing protein beta OS=Homo sapiens OX=9606 GN=DOC2B PE=1 SV=2) HSP 1 Score: 234.572 bits (597), Expect = 1.130e-68 Identity = 132/280 (47.14%), Postives = 174/280 (62.14%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L++ + +D + L TI K LK MD NGL+DPYVK HLLPG + KLRTKT TLNP WNE L Y+GI DM KTLR++V DED ++IGE R+ L L + FS L ++ P+ K D ++ ERG+ILISL ++ + + V IVRC LA MD NG+SDP+ K YL+PD + +K KT KK TLNP FNEEF E+ G +K+LE++VWDYD G +NDFIG V AKG+R K W N +K+ + W L +++
Sbjct: 127 LGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQLPVDKTEDKSLE-ERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTSEL 405
BLAST of Double C2-like domain-containing protein beta vs. UniProt/SwissProt
Match: sp|P70610|DOC2B_RAT (Double C2-like domain-containing protein beta OS=Rattus norvegicus OX=10116 GN=Doc2b PE=1 SV=2) HSP 1 Score: 234.187 bits (596), Expect = 1.608e-68 Identity = 134/276 (48.55%), Postives = 171/276 (61.96%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L++ + +D + L TI K LK MD NGL+DPYVK HLLPG + KLRTKT TLNP WNE L Y+GI DM KTLR++V DED ++IGE R+ L L + FS L ++ P+ K D ++ ERG+ILISL ++ + + V IVRC LA MD NG+SDP+ K YLKPD + +K KT KK TLNP FNEEF E+ G +KTLE++VWDYD G +NDFIG V AKG+R K W N +K+ + W L
Sbjct: 127 LGTLDFSLLYDQENNALHCTISKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPSWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQLPVDKAEDKSLE-ERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKTLEVTVWDYDIGKSNDFIGGVVLGINAKGERLKHWFDCLKNKDKRIERWHTL 401
BLAST of Double C2-like domain-containing protein beta vs. UniProt/SwissProt
Match: sp|P70169|DOC2B_MOUSE (Double C2-like domain-containing protein beta OS=Mus musculus OX=10090 GN=Doc2b PE=1 SV=2) HSP 1 Score: 233.802 bits (595), Expect = 2.195e-68 Identity = 134/280 (47.86%), Postives = 173/280 (61.79%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L++ + +D + L TI K LK MD NGL+DPYVK HLLPG + KLRTKT TLNP WNE L Y+GI DM KTLR++V DED ++IGE R+ L L + FS L ++ P+ K D ++ ERG+ILISL ++ + + V IVRC LA MD NG+SDP+ K YLKPD + +K KT KK TLNP FNEEF E+ G +KTLE++VWDYD G +NDFIG V AKG+R K W N +K+ + W L ++
Sbjct: 127 LGTLDFSLLYDQENNALHCTISKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPSWNETLTYYGITDEDMVRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQLPVDKAEDKSLE-ERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKTLEVTVWDYDIGKSNDFIGGVVLGINAKGERLKHWFDCLKNKDKRIERWHTLTNEL 405
BLAST of Double C2-like domain-containing protein beta vs. UniProt/SwissProt
Match: sp|Q9Y2J0|RP3A_HUMAN (Rabphilin-3A OS=Homo sapiens OX=9606 GN=RPH3A PE=1 SV=1) HSP 1 Score: 231.491 bits (589), Expect = 8.506e-65 Identity = 134/293 (45.73%), Postives = 174/293 (59.39%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDN------------DDLVDH-----ERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + +D S L TI K LK MD NGL+DPYVK HLLPG + KLRTKT T NPIWNE LVYHGI DM KTLR++V DED G ++IGE R L L ++ NF+ L + P+ + ++ V+ ERGKIL+SL+++ + + V I+RC LA MD NG+SDPF K++LKPD + K KTQ KK TLNP FNEEF ++ +K+L+ISVWDYD G +ND+IG + AKG+R K W N +KK + W L
Sbjct: 393 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQL 685 HSP 2 Score: 82.8037 bits (203), Expect = 5.503e-15 Identity = 53/189 (28.04%), Postives = 86/189 (45.50%), Query Frame = 1
Query: 319 DRWICPNDRQLAL--RAKLGTGWSVFT--HKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLP 873
+RW+ P+DR L + +L GWSV + ++ EE + I+ V+ R + +++E+ERIG +V L+N+++N + C +CG + ++ C+ C K C C + NN L S + +CK C E RE+WKRSGAW + P+ LP
Sbjct: 11 NRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACV--VCEDCKKNVCTKCGVET-----------------------------NNRLHS-VWLCKICIEQREVWKRSGAWFFKGFPKQVLP 167
BLAST of Double C2-like domain-containing protein beta vs. UniProt/SwissProt
Match: sp|Q06846|RP3A_BOVIN (Rabphilin-3A OS=Bos taurus OX=9913 GN=RPH3A PE=1 SV=1) HSP 1 Score: 231.491 bits (589), Expect = 8.675e-65 Identity = 134/293 (45.73%), Postives = 174/293 (59.39%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDN------------DDLVDH-----ERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + +D S L TI K LK MD NGL+DPYVK HLLPG + KLRTKT T NPIWNE LVYHGI DM KTLR++V DED G ++IGE R L L ++ NF+ L + P+ + ++ V+ ERGKIL+SL+++ + + V I+RC LA MD NG+SDPF K++LKPD + K KTQ KK TLNP FNEEF ++ +K+L+ISVWDYD G +ND+IG + AKG+R K W N +KK + W L
Sbjct: 403 LGALEFSLLYDQDNSSLHCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQL 695 HSP 2 Score: 87.4261 bits (215), Expect = 1.717e-16 Identity = 53/188 (28.19%), Postives = 85/188 (45.21%), Query Frame = 1
Query: 322 RWICPNDRQLAL--RAKLGTGWSVFT--HKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLP 873
RW+CP+DR L + +L TGWSV + ++ EE + I+ V+ R + +++E+ERIG +V L+N+++N + C +CG + ++ C+ C K C C + S N + +CK C E RE+WKRSGAW + P+ LP
Sbjct: 12 RWMCPSDRPLQSNDKEQLQTGWSVHPSGQPDRQRKQEELTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACV--VCEDCKKNVCTKCGVETS-----------------------------NNRPHPVWLCKICIEQREVWKRSGAWFFKGFPKQVLP 168
BLAST of Double C2-like domain-containing protein beta vs. TrEMBL
Match: A0A1S3J982 (double C2-like domain-containing protein beta isoform X3 OS=Lingula unguis OX=7574 GN=LOC106171243 PE=4 SV=1) HSP 1 Score: 363.999 bits (933), Expect = 6.212e-113 Identity = 244/641 (38.07%), Postives = 334/641 (52.11%), Query Frame = 1
Query: 316 MDRWICPNDRQLALRAKLGTGWSVFTHK-SHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLP---TTNNVCP----HPDSCSKVILNTQVTNIDSASWETYRRPPKWST----MKENREIDINIDEN----QQVEPAFERFS----FNPFEDELKETINKMESSNNISSNPTATLQWNNFNEKFKNDADFGT-KLYRQNPPEGSLFWXXXXXXXXXXXXXXDN-----------LGILNYKIFHDS---ALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
+D W+ PNDRQLALRA+LGTGWSV THK F +S EE + I V++R + + +E+ERIG +V L+N+K+N +C +CG +F + S + C+ CGK C C DT N + +CK C E RE+WKRSGAW + LP + +P T + P HP + + ++ W R ST E+ + +INI + QQ + S F P+ + +S + SS L + K D G Q +GSL + + D+ LG L + + +DS AL +I N K LK+MD NGLSDPYVK HLLPG + TKLR++T ++TLNP WNE L YHG+ D+ KTLRL+VLDED G+D+IGE R+ L L + NF+ L ++ P+ KD DDLV HERGKIL+SL + ++ V IVRC +LAPMD NGFSDP+ K+YLKPDK + +K+KT KK TLNP +NEEF+ E+ + +KTLE++VWD D G +D+IG V+ AKG R K W P+KK + W IL AD+
Sbjct: 10 IDHWVVPNDRQLALRARLGTGWSVHTHKLQTFHKNQQLSVEEQEQILNVIRRAERLELMEQERIGRLVERLENMKKNAIGSGDSQCVLCGDTFGMLGASPT--YCEDCGKAVCTKC----GVDTF-------------------------NSHHQPLWLCKICSEKRELWKRSGAWFFKGLPRYIMPKKKTELDKVPGRGGHPGQGQRSRTGSPAPQYNT--WTRGRVQYGESTDEQESSESSDDEINISKRKVRRQQDSESESEMSTTSDFRPWASRGSMGTVESDSVSIASSGRPNPLMASRPLSDSKTSLDSGQLPSSGQGTGQGSLPSEGPRVQESQDSTVSDSERSATSGVGFSLGTLEFSLMYDSMGNALHCTLIRARNLKALKAMDSNGLSDPYVKLHLLPGASKSTKLRSRTIHKTLNPEWNETLTYHGVIEEDLQRKTLRLSVLDEDAFGYDFIGETRVPLKCLKPHQLKNFNVYLDRQMPLEKD-DDLVAHERGKILVSLTYKASKQSLLVGIVRCVQLAPMDSNGFSDPYVKVYLKPDKEKKSKQKTTVKKKTLNPEYNEEFLYEIPKHELAQKTLELTVWDKDIGRHSDYIGGVQLGITAKGTRLKHWFETLKYPDKKHEYWHILSADV 616
BLAST of Double C2-like domain-containing protein beta vs. TrEMBL
Match: T1JK29 (Uncharacterized protein OS=Strigamia maritima OX=126957 PE=4 SV=1) HSP 1 Score: 306.99 bits (785), Expect = 2.802e-91 Identity = 208/632 (32.91%), Postives = 314/632 (49.68%), Query Frame = 1
Query: 319 DRWICPNDRQLALRAKLGTGWSVFTHK-SHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPTTNNVCPHPDSCSKVILNTQVTNIDSASWETYRRPPKWSTMKENREIDINIDENQQVEPAFERFSFNPFEDELKETINKMESSNNISSNPTATLQWNNFNEKFKNDADFGTKLYRQNPPEGSL------------FWXXXXXXXXXXXXXXDNL-------------GILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHER-GKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
D+W+CPNDRQL+LRAKL +GWSV T + + + ++ +E + I V+KR ++ D +E+ERIG +V L+N+K++ +C +CG F + S C C K C C DT+ + K + +CK C ETREIWK+SGAW + LP+ LP N + S I N Q I + T+ + K + +++ + D+ Q F R S + + + +S++ T + +N + F +R + + S+ + +++ D++ G + + + +DS S L TI + L+ MD NGLSDPYVK HLLPG + KLRT+T ++TLNP +NE L YHGI + ++ KTLRL+VLDED G D+IGE R+ L L + F+ L ++ P+ +D D L GKILISL + + + V I+RC L MD NG SDPF K+ +KPD K KT + LNP FNEEFV ++ KT+EI+VWD D G TND+IG ++ +KG+R + + NP+K+ D W L +++
Sbjct: 11 DKWVCPNDRQLSLRAKLKSGWSVKTGQLNSYQKPEQMNDDEQERIKNVIKRAETIDVVEQERIGRLVEKLENMKKHVMGNGANQCILCGDEFGILGAS--SLACHDCRKGVCSKC----GVDTL-------------------------SAQKDPLWLCKICSETREIWKKSGAWFFKGLPKHILPEKKNTS---NKYSGKISNKQPKPIRGRDFNTWYKSGKGPQDVSDLDVETSSDDEIQKGMLFTRDSLRG-----RSARTSGDRTPRLSASSTRGDEEDNMEQAFNTYGTTHAMHHRDSGSDRSIRSDKSATHEHKSLITTGLNQTVLRESPIDDVFEEKYSPDDIAMFGNVEFSLIYDSINSTLHCTIYRARGLRPMDSNGLSDPYVKLHLLPGASKSNKLRTRTVHKTLNPEFNETLTYHGITQNEILKKTLRLSVLDEDAFGHDFIGETRISLKKLKPHQTKYFNVYLDKQLPLDRDEDILAAESNCGKILISLKYCLQKKALLVGIIRCANLPSMDPNGLSDPFIKVQMKPD-HLRRKYKTTVQWKNLNPEFNEEFVFDVFLQELPNKTVEITVWDKDYGRTNDYIGGLQIGIASKGERLRHFLHTIKNPDKRHDRWHHLSSEV 602
BLAST of Double C2-like domain-containing protein beta vs. TrEMBL
Match: A0A5N5LKW7 (Uncharacterized protein OS=Pangasianodon hypophthalmus OX=310915 GN=PHYPO_G00078480 PE=4 SV=1) HSP 1 Score: 289.271 bits (739), Expect = 4.000e-85 Identity = 206/607 (33.94%), Postives = 284/607 (46.79%), Query Frame = 1
Query: 406 FDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPTTNNVCPHPDSCSKVILN-------TQVTNIDSASWETYRRPPKWSTMKENREIDINIDENQQVEPAFERFSFNPFEDELKETIN-----KMESSNNIS----SNPTATLQWNNFNEKFKNDADFGTKLYRQNPPEGSLFWXXXXXXXXXXXXXXDNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAK------------------DNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
F ++ EE + I+ VL R + + +E+ERIG +V L IKR H +C +CG F L S CD C K C C +N + +CK C E +E+ K+SGAW + LP+ LP P P S K T+ ++ + +Y + MK Q+V P + S + + N K+ES S S P++ +Q + + + PP + + ++ + LG+L + + ++ + L I K LK MD NGL+DPYVK HLLPG + KLRTKT TLNP+WNE LVYHGI DM KTLRL+V DED G ++IGE R+ L L +++ NFS L + P+ + + DD ERG+IL+SL +N + S + V IVRC LAPMD NG+SDP+ KI LKPD + K KTQ KK TLNP FNEEF E+ +KTL+ISVWDYD G +NDFIG + AKG+ K W N +KK + W +L
Sbjct: 3 FTGAEELTDEEKEIINSVLARAELIEAMEQERIGRLVNRLDTIKRTACGDGHSQCLLCGQQFGLMGVSMV--MCDECKKHICTKC------------------------------GIRSNSRSCPVWLCKICSEHKEMLKQSGAWFFKGLPQQILPA-----PLPISKPKQFSTAGDLHAPTEPSSQQGTTAHSYVNTQNGAEMK---------PPEQEVLPVSAQISQTQTQSGAERQSNLTAWKKVESVKRASPVQPSYPSSLMQKGVLQMESRT-------IPTMQPPNSTHTPATGEEVEDYDSDDATTLGMLEFSLLYEEENNTLHCNIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTLNPVWNETLVYHGITNEDMQRKTLRLSVSDEDKFGHNEFIGETRVVLKKLKVNQKKNFSVCLERVIPVKRTAAGGAIRGMALYEEEINEGDDA--EERGRILVSLTYNSQQSQLIVGIVRCAHLAPMDANGYSDPYVKISLKPDMGKKAKNKTQIKKKTLNPEFNEEFSYEIKHSELAKKTLDISVWDYDMGKSNDFIGGCQLGITAKGECLKHWYECLKNKDKKIERWHVL 554
BLAST of Double C2-like domain-containing protein beta vs. TrEMBL
Match: A0A0P7U193 (Rabphilin-3A-like OS=Scleropages formosus OX=113540 GN=Z043_117564 PE=4 SV=1) HSP 1 Score: 288.5 bits (737), Expect = 1.946e-84 Identity = 213/630 (33.81%), Postives = 295/630 (46.83%), Query Frame = 1
Query: 388 FTHKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPTTNNVC----------------PHPDSCSKVILNTQ--------VTNIDSASWETYRR--------PPKWSTM----------------KENREIDINIDENQQVEPAF-ERFSFNPFEDELKETINKMESSNNISSNPTATLQWNNFNEKFKNDADFGTKLYRQ--NPPEGSLFWXXXXXXXXXXXXXXDNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
H SH D +++ EE + I+ V+ R + + +E+ERIG +V L+N+K++ C +CG L + S C+ C K C C S N + +CK C E RE+WKRSGAW + +P+ LPT + P P++ + TQ ++ + + +T PPK + M +EN E ++ ++ P R P + E++ P ATL E + A + RQ +PPE E + ++ LG L + + ++ + L I K LK MD NGL+DPYVK HLLPG + TKLRTKT T NP+WNE LVYHG+ DM KTLRL+V DED G ++IGE R+ L L ++ NF+ L + P KD DL ERG+ILISL++N + S + V +VRC LA MD NG+SDPF KI LKPD + K KTQ KK TLNP FNEEF ++ +KTL+ISVWDYD G ND+IG + AKG+R K W N +KK + W L
Sbjct: 4 MRHASH-DPGPDLTDEEKEIINSVIARAEKMEAMERERIGRLVNQLENMKKSVCGDGVSRCLLCGEQ--LGTPGVSSVVCEDCKKHMCTRC------------------------------SMQNTSRPRAVRLCKICSEQREVWKRSGAWFFKGMPKQFLPTPMPISKNHKSSTQQAKSSAEQPVPETSAAGQPRTQGRGSVEGYISGAERHAADTPHSAQRGYPPVPPKPTEMHMGPAGVGGQCSPHPSEENSEAQDSLVVARRAVPVQNSRPPQAPAKHEMESAYPTALPQLREERGPPATL------EDRRQPAAYNRTPARQQPHPPE-----DDEEEANSYDSDETTALGSLEFSLLYEQENNSLHCCIMRAKGLKPMDSNGLADPYVKLHLLPGASKSTKLRTKTLRNTRNPVWNETLVYHGLTDEDMQRKTLRLSVCDEDKFGHNEFIGETRVALKKLKMNQRKNFNVCLERVVPTGKDIGDL--EERGRILISLMYNSQLSRLIVGVVRCVHLAAMDANGYSDPFVKICLKPDMGKKAKNKTQIKKKTLNPEFNEEFSYDIKHSELAKKTLDISVWDYDIGKCNDYIGGCQLGITAKGERLKHWYECLKNKDKKIEKWHTL 587
BLAST of Double C2-like domain-containing protein beta vs. TrEMBL
Match: A0A226PZU9 (Uncharacterized protein OS=Colinus virginianus OX=9014 GN=H355_016011 PE=4 SV=1) HSP 1 Score: 284.648 bits (727), Expect = 2.835e-82 Identity = 207/647 (31.99%), Postives = 298/647 (46.06%), Query Frame = 1
Query: 319 DRWICPNDRQLALRAKLGTGWSVFTHKSHFDHESN-ISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPTTNNVCPHPDSCSKVILNTQVTNIDSASWETYRRPPKWSTMKENREIDINIDENQQVEPAFERFSFNPFEDELKETINKMESSNNISSNPTATLQWNNFNEKFKNDADFGTKLYRQNPPEGSLFWXXXXXXXXXXXXXXDNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLR----------------------------LAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDN-----------DDLVDH-----ERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
DRW+CP DR ++LRA+L GW+ + + ++ EE + I+ V+ R + +++E+ERIG ++ L++++R+ C +CG ++ C+ C K C C + + N I +CK C E RE+WKRSGAW + LP+ LP P P S SKV + PK + R ++ + + +PA R P E E+ + S +S +P N N P + + + LG L + + +D S L T+ K LK MD NGL+DPYVK HLLPG + KLRTKT T NP+WNE LVYHGI DM KTLR ++V DED G ++IGE R+ L L ++++ NF+ L + P+ + ++ VD ERGKIL+SL+++ + + V IVRC LA MD NG+SDPF K++LKPD + K KTQ KK TLNP FNEEF ++ +K+L+ISVWDYD G +ND+IG + AKG+R K W N +KK + W L
Sbjct: 59 DRWMCPGDRTMSLRARLPAGWAARGGQPERQRKGEELTDEEKEIINRVIARAEKMEEMEQERIGRLMTRLEDMRRSVLGDGVNRCILCGEQLGPRGSACV--VCEDCKKNVCTKCGVETT-----------------------------NSRPHPIWLCKICSEQREVWKRSGAWFFKGLPKQMLPQ-----PMPVSKSKVPPAPSEPSPAEPPTPD----PKLPSRTPGRGSEVTVTARVR-KPAEGRT--GPCGSEDTESRDPTTESG-VSRSPGV----KRANSMQTNSTPPPRPPAATAVPAAPAVARPGPGAASRMLETQATLGALEFSLLYDQENSALHCTLIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLVYHGITDEDMTRKTLRQVEELGNRVVLGRTLLGEGMGRAPGNGEISVCDEDKFGHNEFIGETRVSLKKLKANQKKNFNICLERVIPMKRTGTTGSSRGMALYEEEVDRGGDVEERGKILVSLMYSTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGITAKGERLKHWYECLKNKDKKIERWHTL 657
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Cavefish
Match: doc2d (double C2-like domain-containing protein beta [Source:NCBI gene;Acc:103027347]) HSP 1 Score: 232.261 bits (591), Expect = 8.582e-69 Identity = 135/283 (47.70%), Postives = 171/283 (60.42%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDH-------ERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + D + L TI K LK+MD NGL+DPYVK HLLPG + KLRTKT TLNP+WNE L+YHGI DM +KTLRL V D D +G ++IGE R+ L L E ++ L + + N+ VD ERG+IL+SL + + +++ V I+RC LA MD NG+SDPF KI L+PD + +K KT KK TLNP FNEEF+ E+ +KTLEISVWDYD G +NDFIG V+ AKGDR K W KK + W L
Sbjct: 120 LGTLEFSLLFDQENNCLHCTINKAKGLKAMDSNGLADPYVKLHLLPGASKANKLRTKTLKNTLNPVWNETLMYHGITAADMTTKTLRLCVCDMDRLGRNEFIGEVRVALKKLTEGETKRYNMGLERITQTREGNNQTVDQTSQPAEEERGRILVSLCYMVEKTSLVVGIIRCAHLAAMDSNGYSDPFVKIVLQPDMGKKSKYKTTVKKKTLNPEFNEEFMYEVPLDQLAKKTLEISVWDYDLGMSNDFIGGVELGINAKGDRLKHWFECLKYKGKKVEYWHTL 402
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Cavefish
Match: doc2b (double C2 domain beta [Source:NCBI gene;Acc:103021390]) HSP 1 Score: 230.72 bits (587), Expect = 2.994e-68 Identity = 133/280 (47.50%), Postives = 176/280 (62.86%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L++ + +D + L TI K LK MD NGLSDPYVK HLLPG + KLRTKT TLNP+W+E L Y+GI DM KTLR++V DED ++IGE R+ L L ++ NF + L ++ PI K +D ++ ERG+I+ISL ++ + + V I+RC LA MD NGFSDP+ K YLKPD+ + +K KT KK TLNP FNEEF E+ +KTLE++VWDYD G +NDFIG V A G+R K W N +KK + W L ++
Sbjct: 127 LGTLDFSLLYDQENNALHCTINKAKGLKPMDHNGLSDPYVKLHLLPGASKANKLRTKTLRNTLNPVWSETLTYYGITDEDMVRKTLRISVCDEDKFRHNEFIGETRIPLKKLKPNQTKNFYNCLEKQLPIDKTDDKSLE-ERGRIMISLKYSSQKCGLVVGIIRCAHLAAMDANGFSDPYVKTYLKPDENKKSKHKTTVKKKTLNPEFNEEFFYEIKYADLSKKTLEVTVWDYDIGKSNDFIGGVSLGINANGERLKHWFDCLKNKDKKIERWHTLTNEL 405
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Cavefish
Match: doc2b (double C2 domain beta [Source:NCBI gene;Acc:103021390]) HSP 1 Score: 223.787 bits (569), Expect = 1.665e-65 Identity = 133/288 (46.18%), Postives = 176/288 (61.11%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGK--------DLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L++ + +D + L TI K LK MD NGLSDPYVK HLLPG + KLRTKT TLNP+W+E L Y+GI DM KTLR++V DED ++IGE R+ L L ++ NF + L ++ PI K +D ++ ERG+I+ISL ++ + + V I+RC LA MD NGFSDP+ K YLKPD+ + +K KT KK TLNP FNEEF E+ +KTLE++VWDYD G +NDFIG V A G+R K W N +KK + W L ++
Sbjct: 127 LGTLDFSLLYDQENNALHCTINKAKLPVPRYRKGLKPMDHNGLSDPYVKLHLLPGASKANKLRTKTLRNTLNPVWSETLTYYGITDEDMVRKTLRISVCDEDKFRHNEFIGETRIPLKKLKPNQTKNFYNCLEKQLPIDKTDDKSLE-ERGRIMISLKYSSQKCGLVVGIIRCAHLAAMDANGFSDPYVKTYLKPDENKKSKHKTTVKKKTLNPEFNEEFFYEIKYADLSKKTLEVTVWDYDIGKSNDFIGGVSLGINANGERLKHWFDCLKNKDKKIERWHTLTNEL 413
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Cavefish
Match: doc2a (double C2-like domain-containing protein alpha [Source:NCBI gene;Acc:103036801]) HSP 1 Score: 209.534 bits (532), Expect = 3.554e-60 Identity = 127/308 (41.23%), Postives = 168/308 (54.55%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAK------------------DNDDLVD-HERGKILISLLF---------NDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L +++ ++ A S L TI K LK MD NGLSDPYVK HLLPG + KL+TKT +LNP+WNE L Y GI DM KTLRL+V DED + ++IGE R+ L + D+ F L P+ +N+ L ERG++L+SL F + + V ++RC LA MD NGFSDP+ K YLKPD + +K KT K TLNP FNEEF E+ KTLE++VWDYD G +NDFIG V ++GD + W N +K + W +L ++
Sbjct: 109 LGTLEFELRYERATSSLHCTIIRAKGLKPMDFNGLSDPYVKLHLLPGASKANKLKTKTVRNSLNPVWNETLTYIGITEEDMHRKTLRLSVCDEDKLTHNEFIGESRVALRRVKPDQTKRFYTCLEHPPPLPSPTAMGAALRGISCYLREWENEQLHSLEERGRLLLSLQFLPPPEEGDGEGRRGGLWVGVLRCAHLAAMDVNGFSDPYVKTYLKPDVKKKSKHKTAVIKKTLNPEFNEEFFYEISLSELVSKTLEVTVWDYDLGRSNDFIGGVCLSCHSQGDALRHWMDCLRNKGQKVERWHVLTNEL 416
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Cavefish
Match: ENSAMXT00000036659.1 (double C2-like domain-containing protein alpha [Source:NCBI gene;Acc:103047660]) HSP 1 Score: 201.445 bits (511), Expect = 7.261e-58 Identity = 120/281 (42.70%), Postives = 158/281 (56.23%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
+LG L + + ++SA S L T+ K LK MD NGL+DPYVK HLLPG KL+TK TLNP+WNE L Y GI DM KTLR++V DED + ++IGE R+ L + D+ +F+ L P++ + LV + + F + V + RC LA MD NGFSDP+ K YLKPD + +K KT K TLNP FNEEF E+ KTLE++VWDYD G +NDFIG V ++GD + W N K + W L D+
Sbjct: 88 SLGTLEFDVLYESATSSLHCTVLKAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKIVKNTLNPVWNETLTYCGITEEDMYRKTLRVSVCDEDKLTHNEFIGESRVALRRVKPDQPKHFNVCLEHPPPVSAPSCVLVRK------MDMYFLPPGG-LCVGVRRCAHLAAMDVNGFSDPYVKTYLKPDVKKKSKHKTAVIKKTLNPEFNEEFFYEITFNELATKTLEVTVWDYDLGKSNDFIGGVSLGCHSQGDALQHWIDCLKNKGTKVERWHTLTNDL 361
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004430.1 (pep scaffold:Pmarinus_7.0:GL476335:1496408:1550941:1 gene:ENSPMAG00000004026.1 transcript:ENSPMAT00000004430.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 73.559 bits (179), Expect = 7.969e-14 Identity = 47/119 (39.50%), Postives = 67/119 (56.30%), Query Frame = 1
Query: 1720 GKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKP---------DXXXXXXXXXXXXXXXLNPYFNEEFV---IELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHF 2040
G+I + + F+ + + + +++ LAP D NGFSDPF K+YL P + KR+T+ TLNP +N+ V I LD+ K KTLE SVWDYDR +NDF+G V+
Sbjct: 158 GEIQLQMSFDRHSGNLIIHVLQARGLAPRDNNGFSDPFVKVYLLPGRGQVMVVQNASSENKRRTKYIHKTLNPEWNQTVVYKNIMLDE--LKRKTLEFSVWDYDRFSSNDFLGEVRIEL 274 HSP 2 Score: 72.7886 bits (177), Expect = 1.411e-13 Identity = 42/121 (34.71%), Postives = 65/121 (53.72%), Query Frame = 1
Query: 1300 GILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGK---------THKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLN 1632
G + ++ D L+I + + L D NG SDP+VK +LLPG+ + + K RTK ++TLNP WN+ +VY I ++ KTL +V D D D++GE R+ L D++
Sbjct: 158 GEIQLQMSFDRHSGNLIIHVLQARGLAPRDNNGFSDPFVKVYLLPGRGQVMVVQNASSENKRRTKYIHKTLNPEWNQTVVYKNIMLDELKRKTLEFSVWDYDRFSSNDFLGEVRIELSDVS 278
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004426.1 (pep scaffold:Pmarinus_7.0:GL476335:1496408:1550941:1 gene:ENSPMAG00000004026.1 transcript:ENSPMAT00000004426.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 73.1738 bits (178), Expect = 1.172e-13 Identity = 47/119 (39.50%), Postives = 67/119 (56.30%), Query Frame = 1
Query: 1720 GKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKP---------DXXXXXXXXXXXXXXXLNPYFNEEFV---IELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHF 2040
G+I + + F+ + + + +++ LAP D NGFSDPF K+YL P + KR+T+ TLNP +N+ V I LD+ K KTLE SVWDYDR +NDF+G V+
Sbjct: 161 GEIQLQMSFDRHSGNLIIHVLQARGLAPRDNNGFSDPFVKVYLLPGRGQVMVVQNASSENKRRTKYIHKTLNPEWNQTVVYKNIMLDE--LKRKTLEFSVWDYDRFSSNDFLGEVRIEL 277 HSP 2 Score: 72.4034 bits (176), Expect = 1.714e-13 Identity = 42/121 (34.71%), Postives = 65/121 (53.72%), Query Frame = 1
Query: 1300 GILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGK---------THKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLN 1632
G + ++ D L+I + + L D NG SDP+VK +LLPG+ + + K RTK ++TLNP WN+ +VY I ++ KTL +V D D D++GE R+ L D++
Sbjct: 161 GEIQLQMSFDRHSGNLIIHVLQARGLAPRDNNGFSDPFVKVYLLPGRGQVMVVQNASSENKRRTKYIHKTLNPEWNQTVVYKNIMLDELKRKTLEFSVWDYDRFSSNDFLGEVRIELSDVS 281
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Sea Lamprey
Match: syt2a (synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503-315]) HSP 1 Score: 68.5514 bits (166), Expect = 2.308e-13 Identity = 41/107 (38.32%), Postives = 61/107 (57.01%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIG-FDWIGEYRL 1614
LG L + I +D +QL + + +L ++D+ G SDPYVK L+P K K K TK +TLNP++NE V+ + ++ KTL +AV D D D IGE ++
Sbjct: 80 LGKLQFSIDYDFQNNQLTVGVIQAAELPALDMGGTSDPYVKLFLMPDK--KKKYETKVHRKTLNPVFNESFVFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEVKV 183 HSP 2 Score: 67.781 bits (164), Expect = 3.373e-13 Identity = 39/104 (37.50%), Postives = 64/104 (61.54%), Query Frame = 1
Query: 1720 GKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVK 2031
GK+ S+ ++ +N+ + V +++ EL +D G SDP+ K++L PD + K +T+ + TLNP FNE FV ++ KTL ++V+D+DR +D IG VK
Sbjct: 81 GKLQFSIDYDFQNNQLTVGVIQAAELPALDMGGTSDPYVKLFLMPD--KKKKYETKVHRKTLNPVFNESFVFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEVK 182
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Sea Lamprey
Match: SYT5 (synaptotagmin 5 [Source:HGNC Symbol;Acc:HGNC:11513]) HSP 1 Score: 68.5514 bits (166), Expect = 2.394e-13 Identity = 41/115 (35.65%), Postives = 62/115 (53.91%), Query Frame = 1
Query: 1291 DNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIG-FDWIGEYRLFLPDLN 1632
+ LG L + + ++ SQ + I DL +MDI G+SDPYV+ +LLP K K K T +TLNPI+ EK + + ++ + L + V D D D IGE R+ L ++
Sbjct: 77 NTLGRLQFSLDYNLKTSQFTVGILQATDLAAMDIGGMSDPYVRVYLLPHK--KKKFETSVHRKTLNPIFEEKFTF-TVPFEELVERVLVMVVYDFDRFSRHDIIGELRIPLSSVD 188 HSP 2 Score: 63.929 bits (154), Expect = 7.165e-12 Identity = 38/101 (37.62%), Postives = 57/101 (56.44%), Query Frame = 1
Query: 1720 GKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIG 2022
G++ SL +N K S V I++ T+LA MD G SDP+ ++YL P + K +T + TLNP F E+F + E+ L + V+D+DR +D IG
Sbjct: 80 GRLQFSLDYNLKTSQFTVGILQATDLAAMDIGGMSDPYVRVYLLP--HKKKKFETSVHRKTLNPIFEEKFTFTVPFEELVERVLVMVVYDFDRFSRHDIIG 178
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Sea Lamprey
Match: syt2a (synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503-315]) HSP 1 Score: 68.9366 bits (167), Expect = 2.436e-13 Identity = 39/104 (37.50%), Postives = 64/104 (61.54%), Query Frame = 1
Query: 1720 GKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVK 2031
GK+ S+ ++ +N+ + V +++ EL +D G SDP+ K++L PD + K +T+ + TLNP FNE FV ++ KTL ++V+D+DR +D IG VK
Sbjct: 98 GKLQFSIDYDFQNNQLTVGVIQAAELPALDMGGTSDPYVKLFLMPD--KKKKYETKVHRKTLNPVFNESFVFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEVK 199 HSP 2 Score: 68.9366 bits (167), Expect = 2.602e-13 Identity = 41/107 (38.32%), Postives = 61/107 (57.01%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIG-FDWIGEYRL 1614
LG L + I +D +QL + + +L ++D+ G SDPYVK L+P K K K TK +TLNP++NE V+ + ++ KTL +AV D D D IGE ++
Sbjct: 97 LGKLQFSIDYDFQNNQLTVGVIQAAELPALDMGGTSDPYVKLFLMPDK--KKKYETKVHRKTLNPVFNESFVFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEVKV 200
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Nematostella
Match: EDO41933 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S352]) HSP 1 Score: 214.157 bits (544), Expect = 5.679e-64 Identity = 123/277 (44.40%), Postives = 171/277 (61.73%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG+L + + + S+L + + + K LK MD G SDPYVK HLLPG + KLR+ T Y+TLNP++NE L Y+GI ++ SKTLRL V DEDTIG D+IGE + L LNS+ F +L+ P A D+ G+I ++L +N + + VT++RC+ LA MD NG+SDP+ K YLKPD + +KR+T +K TLNP FNEEFV ++ +K+LE++VWDYD G +NDFIG V + A+G K W + PN+ W L
Sbjct: 18 GLGLLEFTLRYQKLDSRLDVVLHDAKGLKPMDHGGTSDPYVKLHLLPGASKSNKLRSHTKYKTLNPVFNETLTYYGITEEEISSKTLRLQVFDEDTIGRNDFIGETSINLKLLNSNPTQTFKRSLI---PKALDSPH---SPLGRIQLALKYNTQRGMLFVTVMRCSGLASMDANGYSDPYVKCYLKPDPQKKSKRRTNIRKKTLNPEFNEEFVYDIAHHELAKKSLEVTVWDYDVGKSNDFIGGVILNINAEGSALKHWYDMLKGPNQLHTQWHTL 288
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Nematostella
Match: EDO43704 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXY7]) HSP 1 Score: 128.642 bits (322), Expect = 2.844e-33 Identity = 90/276 (32.61%), Postives = 142/276 (51.45%), Query Frame = 1
Query: 1291 DNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLN-SDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGW 2112
+ LG + + + + S+ S L + + + L + D +G SDP+VK LLP K HK L T+ + LNP+WNE + G + KTL + VLD D D IGE + L +++ F+ +LL P KD L G +L+SL++ N+ I V +++ +L MD G SDP+ K+Y+ R+ K+KT K+ T +P +NE F+ ++ ++ T +V DYDR N+ IG V +R G + W + +NP K W
Sbjct: 1 EQLGKIFFSLTYYSSDSVLTLKVLKAQGLPAKDFSGTSDPFVKIMLLPDKKHK--LETRVKRKNLNPVWNEVFTFEGFPHNKLMGKTLYMQVLDYDRFSRNDPIGEVEIPLENIDLGPVTLTFTKDLL---PCKKDRVPL-----GDLLVSLMYQPTNNRIIVVVMKANKLKAMDLTGSSDPYVKMYIMHKDRRLDKKKTTIKRRTRDPVWNESFIFDVPLDKIRDLTFVFNVMDYDRITQNELIGQVILGYRTTGSSLRHWTEMMNNPRKPVAQW 266
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Nematostella
Match: EDO31746 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX17]) HSP 1 Score: 119.783 bits (299), Expect = 1.904e-29 Identity = 89/276 (32.25%), Postives = 137/276 (49.64%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIG-FDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
+G +N+ + + + L + I +D+ + D +G SDPYVK LLP K K K TK +TLNP++NE+ V+ I ++ ++ L + + D D D IGE R LP ++ D N + + P + G I SL + + +Q+TIV L MD G+SDP+ KI L + +I K+KT KK TLNPY+NE F + ++ +L ISV DYDR ++ IG + G + W + +P + W L
Sbjct: 84 IGRINFTLDYSFTDNTLTVGIIRAEDIPAKDFSGSSDPYVKIMLLPDK--KKKYETKVHRKTLNPVFNEQFVFKNIPYSEITNRILLMELFDFDRFSRHDLIGEAR--LPLIDVDLASNINEWRVLTPPSGSGGAGHSKSDLGDICFSLRYVPSSGKLQITIVEAKSLKSMDLTGYSDPYVKIALVQEGRKIKKKKTTVKKRTLNPYYNETFTFTVAFEKIEQTSLIISVLDYDRVGKSEMIGKCVVGELSSGADLRHWADMLASPRRSVAQWHTL 355 HSP 2 Score: 51.6026 bits (122), Expect = 6.214e-7 Identity = 35/98 (35.71%), Postives = 54/98 (55.10%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIG 1587
+LG + + + + + +L ITI K LKSMD+ G SDPYVK L+ K +T RTLNP +NE + + ++ +L ++VLD D +G
Sbjct: 220 DLGDICFSLRYVPSSGKLQITIVEAKSLKSMDLTGYSDPYVKIALVQEGRKIKKKKTTVKKRTLNPYYNETFTFT-VAFEKIEQTSLIISVLDYDRVG 316
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Nematostella
Match: EDO41935 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S354]) HSP 1 Score: 95.1301 bits (235), Expect = 9.072e-23 Identity = 58/183 (31.69%), Postives = 85/183 (46.45%), Query Frame = 1
Query: 319 DRWICPNDRQLALRAKLGTGWSVFTHK-SHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEF 864
+RW CPNDRQL LRAKL GWS + + ++ IS E + I V++R D E+ R+G +V L+N++ N C +C F L T ++CD C K CE C DT +N + I +C C E RE+WK++GAW + +P++
Sbjct: 10 NRWTCPNDRQLVLRAKLNAGWSFHSGGPAKKPAKTTISEAEQEIIKNVIQRADRIQLQEEGRVGRLVEKLENLRNNAIGNGRDTCLLCASKFGLLKTI--DKECDICEKNVCEKC----GVDT-------------------------HNSVGQPIWLCVLCSEQRELWKKTGAWFFKSIPKY 161
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Nematostella
Match: EDO29765 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2P9]) HSP 1 Score: 82.8037 bits (203), Expect = 2.625e-17 Identity = 73/249 (29.32%), Postives = 115/249 (46.18%), Query Frame = 1
Query: 1300 GILNYKIFHDSALSQLVITICNGKDLKSMDING-LSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDED-TIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIA------KDNDDL-VDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVI-ELDQGWYKEKTLEISVWDYDRGPTNDF 2016
G + + +D +L + + +D+ +D SDPY LLP K K+K +T T + LNP WN Y + ++ ++L L V D D D++G RL + N + + + +A K+ ++ V E+ K + V I+ L D +G SDPFCKI L PDK T+ KT K TLNP ++ + EL Q +++ LEIS+WD+D ++F
Sbjct: 21 GEVQVGLRYDYKHEKLEVQVHRARDIAPVDTKKKRSDPY----LLPDKGRKSKRKTPTIRKNLNPQWNFPFTYDDVTLEELMDRSLELTVWDWDRGASNDFLGGVRLGMETRNYSSRHRVRYWFVGMCTMAPGVGRGKNKGEVYVTAEKVKRKSKRQSIASKGELHVHIMEAKNLPGKDADGMSDPFCKITLLPDKKGKTRHKTAIIKRTLNPSWDYNLIYEELSQEELRQRVLEISIWDHDIASRDEF 265 HSP 2 Score: 58.9214 bits (141), Expect = 1.896e-9 Identity = 41/114 (35.96%), Postives = 69/114 (60.53%), Query Frame = 1
Query: 1720 GKILISLLFNDKNSTIQVTIVRCTELAPMDCNG-FSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFV---IELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAK 2049
G++ + L ++ K+ ++V + R ++AP+D SDP YL PDK R +KRKT T + LNP +N F + L++ +++LE++VWD+DRG +NDF+G V+ +
Sbjct: 21 GEVQVGLRYDYKHEKLEVQVHRARDIAPVDTKKKRSDP----YLLPDKGRKSKRKTPTIRKNLNPQWNFPFTYDDVTLEE--LMDRSLELTVWDWDRGASNDFLGGVRLGMETR 128
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Medaka
Match: doc2d (double C2-like domain-containing protein beta [Source:NCBI gene;Acc:101154838]) HSP 1 Score: 234.958 bits (598), Expect = 1.042e-69 Identity = 136/283 (48.06%), Postives = 170/283 (60.07%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDH-------ERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
LG L + + D + L TI K LK+MD NGL+DPYVK HLLPG + KLRTKT TLNP+WNE L+YHGI DM +KTLRL V D D +G ++IGE R+ L L E ++ L + + N+ LVD ERG+IL+SL +N + S + V I+RC LA MD NG+SDPF KI L+PD + +K KT KK TLNP FNEEF ++ +KTLEISVWDYD G +NDFIG V+ A G R K W N KK + W L
Sbjct: 132 LGTLEFTLLFDQENNCLHCTIHKAKGLKAMDSNGLADPYVKLHLLPGASKANKLRTKTLKNTLNPVWNETLIYHGITGADMTTKTLRLCVCDMDRLGRNEFIGEVRVALKKLKEGENKRYNMGLERIAQNKETNNQLVDQGALVGEEERGRILVSLCYNTEKSCLLVGIIRCAHLAAMDSNGYSDPFVKIILQPDMGKKSKYKTSVKKKTLNPEFNEEFSYDVSLDQLAKKTLEISVWDYDLGMSNDFIGGVELGINASGQRLKHWFECLKNKGKKVEYWHTL 414
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Medaka
Match: doc2b (double C2 domain beta [Source:NCBI gene;Acc:101156272]) HSP 1 Score: 233.417 bits (594), Expect = 1.973e-69 Identity = 132/280 (47.14%), Postives = 176/280 (62.86%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L + + +D + L TI K LK MD NGLSDPYVK HLLPG + KLRTKT TL+P+WNE L Y+GI DM KTLR++V DED ++IGE R+ L L ++ +F++ L ++ P+ K D ++ ERG+I+ISL +N + S + V I+RC LA MD NGFSDP+ K YLKPD+ + +K KT KK TLNP FNEEF ++ +KTLE++VWDYD G +NDFIG V A G+R K W N +KK + W L ++
Sbjct: 110 LGTLEFSLQYDQENNALHCTINKAKGLKPMDHNGLSDPYVKLHLLPGASKANKLRTKTLRNTLHPVWNETLTYYGITDEDMVRKTLRISVCDEDKFRHNEFIGETRIPLKKLKPNQVKSFNNCLEKQLPVNKTEDKSLE-ERGRIMISLKYNTQKSCLVVGIIRCAHLAAMDANGFSDPYVKTYLKPDENKKSKHKTAVKKKTLNPEFNEEFCYDIKYADLTKKTLEVTVWDYDIGKSNDFIGGVSLGINANGERLKHWFDCLKNKDKKIERWHTLTNEL 388
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Medaka
Match: doc2b (double C2 domain beta [Source:NCBI gene;Acc:101156272]) HSP 1 Score: 224.557 bits (571), Expect = 2.779e-66 Identity = 131/297 (44.11%), Postives = 176/297 (59.26%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDN-----------------DDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L + + +D + L TI K LK MD NGLSDPYVK HLLPG + KLRTKT TL+P+WNE L Y+GI DM KTLR++V DED ++IGE R+ L L ++ +F++ L ++ P++ + +D ERG+I+ISL +N + S + V I+RC LA MD NGFSDP+ K YLKPD+ + +K KT KK TLNP FNEEF ++ +KTLE++VWDYD G +NDFIG V A G+R K W N +KK + W L ++
Sbjct: 78 LGTLEFSLQYDQENNALHCTINKAKGLKPMDHNGLSDPYVKLHLLPGASKANKLRTKTLRNTLHPVWNETLTYYGITDEDMVRKTLRISVCDEDKFRHNEFIGETRIPLKKLKPNQVKSFNNCLEKQLPVSPTSIDAAYRSECFVSEVNKTEDKSLEERGRIMISLKYNTQKSCLVVGIIRCAHLAAMDANGFSDPYVKTYLKPDENKKSKHKTAVKKKTLNPEFNEEFCYDIKYADLTKKTLEVTVWDYDIGKSNDFIGGVSLGINANGERLKHWFDCLKNKDKKIERWHTLTNEL 374 HSP 2 Score: 57.7658 bits (138), Expect = 1.784e-8 Identity = 40/114 (35.09%), Postives = 62/114 (54.39%), Query Frame = 1
Query: 1708 DHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIE--LDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFR 2043
D G + SL ++ +N+ + TI + L PMD NG SDP+ K++L P + K +T+T + TL+P +NE D+ + KTL ISV D D+ N+FIG + +
Sbjct: 75 DTTLGTLEFSLQYDQENNALHCTINKAKGLKPMDHNGLSDPYVKLHLLPGASKANKLRTKTLRNTLHPVWNETLTYYGITDEDMVR-KTLRISVCDEDKFRHNEFIGETRIPLK 187
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Medaka
Match: doc2a (double C2-like domain-containing protein alpha [Source:NCBI gene;Acc:101167710]) HSP 1 Score: 214.542 bits (545), Expect = 1.811e-62 Identity = 124/299 (41.47%), Postives = 170/299 (56.86%), Query Frame = 1
Query: 1297 LGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAK------------------DNDDLVD-HERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
LG L +++ ++ S+L T+ K LK MD NGL+DPYVK HLLPG + KL+TKT +LNP+WNE L+Y GI DM KTLRL V DED + + IGE R+ L L + +F L P+ +N+ L ERG++L+SL +N + V + RC LA MD NGFSDP+ KIYLKPD + +K KT +K TLNP ++EEF E+ +KTLE++VWDYD G +NDFIG V R+KGD + W N ++ + W +L ++
Sbjct: 85 LGTLEFELRYEQISSELHCTVLKAKGLKPMDFNGLADPYVKLHLLPGASKANKLKTKTIRNSLNPVWNETLIYVGITEEDMHRKTLRLTVCDEDKLTHNELIGESRVPLKRLKPNVTKHFHTCLEHPPPLPSPSAVGEALRGISCYLREWENEQLHSLEERGRLLLSLGDGRRNGGLCVAVKRCAHLAAMDVNGFSDPYVKIYLKPDIKKKSKHKTAVRKKTLNPEYDEEFFYEISLTELAKKTLEVTVWDYDLGRSNDFIGGVSLSCRSKGDALRHWMDCLKNKGRRVERWHVLTNEL 383
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Medaka
Match: ENSORLT00000031837.1 (double C2-like domain-containing protein alpha [Source:NCBI gene;Acc:101175439]) HSP 1 Score: 206.068 bits (523), Expect = 2.689e-59 Identity = 124/304 (40.79%), Postives = 163/304 (53.62%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGF-DWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIA-------------------KDNDDLVDHERGKILISLLFNDKNSTIQ----VTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADM 2133
+LG L + + ++ A S L T+ K LK MD NGL+DPYVK HLLPG KL+TK TLNP+WNE L Y GI DM KTLR++V DED + ++IGE R+ L + D+ +F+ L P+ + ERG++L+ L F N + + V + RC LA MD NGFSDP+ K YLKPD + +K KT K TLNP FNEEF E+ KTLE++VWDYD G +NDFIG V ++GD + W N KK + W L D+
Sbjct: 77 SLGTLEFDLLYERATSSLHCTVLRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKIVRNTLNPVWNETLTYCGITEEDMYRKTLRVSVCDEDKLTHNEFIGESRVALRRVKPDQTKHFNICLEHPPPLPSPTAMNTALRGISCYLKEWETEQQRSLEERGRLLLCLQFLPPNKSARGGLCVGVKRCAHLAAMDVNGFSDPYVKTYLKPDVQKKSKHKTAVIKKTLNPEFNEEFFYEISFSELATKTLEVTVWDYDLGRSNDFIGGVSLGCHSQGDALQHWIDCLKNKGKKVERWHTLTNDL 380
BLAST of Double C2-like domain-containing protein beta vs. Planmine SMEST
Match: SMESG000009083.1 (SMESG000009083.1) HSP 1 Score: 1165.98 bits (3015), Expect = 0.000e+0 Identity = 610/610 (100.00%), Postives = 610/610 (100.00%), Query Frame = 1
Query: 316 MDRWICPNDRQLALRAKLGTGWSVFTHKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCXXXXXXXXXXXXXXFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPTTNNVCPHPDSCSKVILNTQVTNIDSASWETYRRPPKWSTMKENREIDINIDENQQVEPAFERFSFNPFEDELKETINKMESSNNISSNPTATLQWNNFNEKFKNDADFGTKLYRQNPPEGSLFWXXXXXXXXXXXXXXDNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADMSDVD 2145
MDRWICPNDRQLALRAKLGTGWSVFTHKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCSESEISESLIKKLSFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPTTNNVCPHPDSCSKVILNTQVTNIDSASWETYRRPPKWSTMKENREIDINIDENQQVEPAFERFSFNPFEDELKETINKMESSNNISSNPTATLQWNNFNEKFKNDADFGTKLYRQNPPEGSLFWSQESFSKEKKKNKEDNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDKIRITKRKTQTKKMTLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADMSDVD
Sbjct: 1 MDRWICPNDRQLALRAKLGTGWSVFTHKSHFDHESNISPEELQHISMVLKRKDSCDKIEKERIGHMVLHLQNIKRNKSQYSHRECHICGHSFLLFSTSFSKRQCDTCGKTTCENCISQLSKDTIEKNCSESEISESLIKKLSFIISFPNNGLKSRITICKYCFETREIWKRSGAWKIQQLPEFCLPTTNNVCPHPDSCSKVILNTQVTNIDSASWETYRRPPKWSTMKENREIDINIDENQQVEPAFERFSFNPFEDELKETINKMESSNNISSNPTATLQWNNFNEKFKNDADFGTKLYRQNPPEGSLFWSQESFSKEKKKNKEDNLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIGFDWIGEYRLFLPDLNSDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDKIRITKRKTQTKKMTLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFILCADMSDVD 610
BLAST of Double C2-like domain-containing protein beta vs. Planmine SMEST
Match: SMESG000055143.1 (SMESG000055143.1) HSP 1 Score: 120.939 bits (302), Expect = 3.790e-29 Identity = 94/280 (33.57%), Postives = 141/280 (50.36%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIG-FDWIGEYRLFLPDLN---SDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
NLG L Y + +D +L + + DL +MD++G SDPYVK LLP K K K TK + LNP++NE V+ I ++ SKTL V D D D IG+ ++ L ++ EE+ ++ D+D+ ++ G I SL + + + + I+ L MD G SDP+ K+ L + R+ K+KT KK TLNPY+NE F E+ ++ L ++V DYDR T++ IG V A G + W + NP + W L
Sbjct: 133 NLGKLQYSLDYDFTKGELTVGVVQATDLPAMDMSGTSDPYVKVFLLPDK--KKKFETKVHRKILNPVFNETFVFK-IPYSEVGSKTLVFNVFDFDRFSKHDQIGQIQIPLGSVDLCKVIEEW--------KELGPPDSDNEKENRLGDICFSLRYVPTSGKLNIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRVVLGCNATGAELRHWSDMLANPRRPIAQWHTL 401
BLAST of Double C2-like domain-containing protein beta vs. Planmine SMEST
Match: SMESG000055143.1 (SMESG000055143.1) HSP 1 Score: 120.553 bits (301), Expect = 4.302e-29 Identity = 94/280 (33.57%), Postives = 141/280 (50.36%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIG-FDWIGEYRLFLPDLN---SDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
NLG L Y + +D +L + + DL +MD++G SDPYVK LLP K K K TK + LNP++NE V+ I ++ SKTL V D D D IG+ ++ L ++ EE+ ++ D+D+ ++ G I SL + + + + I+ L MD G SDP+ K+ L + R+ K+KT KK TLNPY+NE F E+ ++ L ++V DYDR T++ IG V A G + W + NP + W L
Sbjct: 129 NLGKLQYSLDYDFTKGELTVGVVQATDLPAMDMSGTSDPYVKVFLLPDK--KKKFETKVHRKILNPVFNETFVFK-IPYSEVGSKTLVFNVFDFDRFSKHDQIGQIQIPLGSVDLCKVIEEW--------KELGPPDSDNEKENRLGDICFSLRYVPTSGKLNIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRVVLGCNATGAELRHWSDMLANPRRPIAQWHTL 397
BLAST of Double C2-like domain-containing protein beta vs. Planmine SMEST
Match: SMESG000055143.1 (SMESG000055143.1) HSP 1 Score: 120.939 bits (302), Expect = 4.911e-29 Identity = 94/280 (33.57%), Postives = 141/280 (50.36%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIG-FDWIGEYRLFLPDLN---SDEEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
NLG L Y + +D +L + + DL +MD++G SDPYVK LLP K K K TK + LNP++NE V+ I ++ SKTL V D D D IG+ ++ L ++ EE+ ++ D+D+ ++ G I SL + + + + I+ L MD G SDP+ K+ L + R+ K+KT KK TLNPY+NE F E+ ++ L ++V DYDR T++ IG V A G + W + NP + W L
Sbjct: 145 NLGKLQYSLDYDFTKGELTVGVVQATDLPAMDMSGTSDPYVKVFLLPDK--KKKFETKVHRKILNPVFNETFVFK-IPYSEVGSKTLVFNVFDFDRFSKHDQIGQIQIPLGSVDLCKVIEEW--------KELGPPDSDNEKENRLGDICFSLRYVPTSGKLNIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRVVLGCNATGAELRHWSDMLANPRRPIAQWHTL 413
BLAST of Double C2-like domain-containing protein beta vs. Planmine SMEST
Match: SMESG000025329.1 (SMESG000025329.1) HSP 1 Score: 116.701 bits (291), Expect = 7.523e-28 Identity = 91/280 (32.50%), Postives = 142/280 (50.71%), Query Frame = 1
Query: 1294 NLGILNYKIFHDSALSQLVITICNGKDLKSMDINGLSDPYVKCHLLPGKTHKTKLRTKTCYRTLNPIWNEKLVYHGINRIDMDSKTLRLAVLDEDTIG-FDWIGEYRLFLPDLNSD---EEYNFSHNLLQRQPIAKDNDDLVDHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRAKGDRGKLWKAVYDNPNKKFDGWFIL 2121
+LG L Y + +D +L + + DL +MD++G SDPYVK +LLP K K K TK + LNP++NE V+ + ++ SKTL V D D D IG+ ++ L ++ EE+ ++ + +ND ++ G I SL + + + + I+ L MD G SDP+ K+ L + R+ K+KT KK TLNPY+NE F E+ ++ L ++V DYDR T++ IG + A G + W + NP + W L
Sbjct: 120 HLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDK--KKKFETKVHRKILNPVFNETFVFK-VPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEW--------KELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTL 388 HSP 2 Score: 66.2402 bits (160), Expect = 3.035e-11 Identity = 41/113 (36.28%), Postives = 64/113 (56.64%), Query Frame = 1
Query: 1708 DHERGKILISLLFNDKNSTIQVTIVRCTELAPMDCNGFSDPFCKIYLKPDXXXXXXXXXXXXXXXLNPYFNEEFVIELDQGWYKEKTLEISVWDYDRGPTNDFIGVVKFHFRA 2046
D GK+ SL ++ + + V +++ T+L MD +G SDP+ K+YL PD + K +T+ + LNP FNE FV ++ KTL +V+D+DR +D IG +K A
Sbjct: 118 DVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPD--KKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGA 228 The following BLAST results are available for this feature:
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Double C2-like domain-containing protein beta vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Double C2-like domain-containing protein beta vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Double C2-like domain-containing protein beta vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Double C2-like domain-containing protein beta vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30000488 ID=SMED30000488|Name=Double C2-like domain-containing protein beta|organism=Schmidtea mediterranea sexual|type=transcript|length=2155bpback to top protein sequence of SMED30000488-orf-1 >SMED30000488-orf-1 ID=SMED30000488-orf-1|Name=SMED30000488-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=611bp MDRWICPNDRQLALRAKLGTGWSVFTHKSHFDHESNISPEELQHISMVLKback to top Aliases
The feature 'Double C2-like domain-containing protein beta' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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