Stromal cell-derived factor 2

Overview


Name	Stromal cell-derived factor 2
Smed ID	SMED30000463
Length (bp)	887

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Stromal cell-derived factor 2 (SMED30000463) t-SNE clustered cells

Violin plots show distribution of expression levels for Stromal cell-derived factor 2 (SMED30000463) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Stromal cell-derived factor 2 (SMED30000463) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Stromal cell-derived factor 2 (SMED30000463) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30000463

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30000463	h1SMcG0003062	Contig4578	GPL15192	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30000463	h1SMcG0008326	Contig4578	GPL15192	PMID:29674431 Fincher et al., 2018
epidermis	SMED30000463	h1SMcG0008326	dd_Smed_v4_1307_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30000463	h1SMcG0008326	dd_Smed_v4_1307_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Human
Match: SDF2 (stromal cell derived factor 2 [Source:HGNC Symbol;Acc:HGNC:10675])

HSP 1 Score: 197.208 bits (500), Expect = 3.616e-62
Identity = 106/179 (59.22%), Postives = 134/179 (74.86%), Query Frame = 2

Query:  119 VTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
            VTCGSV+KLLN  HNVRLHSHDV+YG GSGQQSVTGV S DD+NSYW+++ +S T   C RG P+KCGQ +RL H++TGRNLHSHHF SPL+ N EVSAFG+ G GD  DDW + C+ G +W R+  +  KHS+    L V+GE+YGRPI GQ E+  + + S++  W A EG+F+KPS
Sbjct:   24 VTCGSVVKLLNTRHNVRLHSHDVRYGSGSGQQSVTGVTSVDDSNSYWRIRGKSATV--CERGTPIKCGQPIRLTHVNTGRNLHSHHFTSPLSGNQEVSAFGEEGEGDYLDDWTVLCN-GPYWVRDGEVRFKHSSTEVLLSVTGEQYGRPISGQKEVHGMAQPSQNNYWKAMEGIFMKPS 199

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Human
Match: SDF2L1 (stromal cell derived factor 2 like 1 [Source:HGNC Symbol;Acc:HGNC:10676])

HSP 1 Score: 197.208 bits (500), Expect = 4.073e-62
Identity = 109/198 (55.05%), Postives = 139/198 (70.20%), Query Frame = 2

Query:  113 DYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL 706
            + VTCGSVLKLLN  H VRLHSHD+KYG GSGQQSVTGV++SDD NSYW++  R G+   C RG PV+CGQ VRL H+ TG+NLH+HHF SPL+NN EVSAFG++G GD+ D W ++CS G HW+R   +  +H     +L V+GE+YG PI GQ E+  +   +    W A EG+F+KPSVE        S+ H+EL
Sbjct:   34 ELVTCGSVLKLLNTHHRVRLHSHDIKYGSGSGQQSVTGVEASDDANSYWRI--RGGSEGGCPRGSPVRCGQAVRLTHVLTGKNLHTHHFPSPLSNNQEVSAFGEDGEGDDLDLWTVRCS-GQHWEREAAVRFQHVGTSVFLSVTGEQYGSPIRGQHEVHGMPSANTHNTWKAMEGIFIKPSVEP-------SAGHDEL 221

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Human
Match: SDF2 (stromal cell derived factor 2 [Source:HGNC Symbol;Acc:HGNC:10675])

HSP 1 Score: 115.931 bits (289), Expect = 6.169e-32
Identity = 66/94 (70.21%), Postives = 78/94 (82.98%), Query Frame = 2

Query:  119 VTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNN 400
            VTCGSV+KLLN  HNVRLHSHDV+YG GSGQQSVTGV S DD+NSYW+++ +S T   C RG P+KCGQ +RL H++TGRNLHSHHF SPL+ N
Sbjct:    5 VTCGSVVKLLNTRHNVRLHSHDVRYGSGSGQQSVTGVTSVDDSNSYWRIRGKSATV--CERGTPIKCGQPIRLTHVNTGRNLHSHHFTSPLSGN 96

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Human
Match: POMT2 (protein O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:19743])

HSP 1 Score: 54.299 bits (129), Expect = 1.438e-7
Identity = 45/163 (27.61%), Postives = 74/163 (45.40%), Query Frame = 2

Query:  242 DNNSYWQVKERSGTTKQCIRGRPVKC---GQTVRLMHLSTGRNLHSHHFKSPLT-NNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHA----YLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL 706
            D N+ W +K+ +  +       PV+    G  +RL H  T RNLHSH+ ++P+T  +++V+ +G NG GD  D W I+        R + +  +   IH      L  SG+   +    Q E++C      +   I      + P + + S+D  Q S  E L
Sbjct:  380 DYNNLWIIKKHNTNSDPLDPSFPVEFVRHGDIIRLEHKETSRNLHSHYHEAPMTRKHYQVTGYGINGTGDSNDFWRIEVVNRKFGNRIKVLRSRIRFIHLVTGCVLGSSGKVLPKWGWEQLEVTCTPYLKETLNSIWNVEDHINPKLPNISLDVLQPSFPEIL 542

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Celegans
Match: R12E2.13 (pep chromosome:WBcel235:I:4177305:4178447:-1 gene:WBGene00020038.1 transcript:R12E2.13.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:R12E2.13)

HSP 1 Score: 155.606 bits (392), Expect = 1.901e-46
Identity = 89/180 (49.44%), Postives = 117/180 (65.00%), Query Frame = 2

Query:  113 DYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNF-EVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVK 649
            D+VTC SVLK +NA    RLHSHDVKYG GSGQQSVT V +SDD NS+WQ+        +C RG  +KCG  +RL HL+TG  LHSHHF +PL+    EVSAFG     D GDDW + C+ G  W  +E   L+H+   +YL +SG+++GRPI GQ E+   +  +  + W  AEG+++K
Sbjct:   24 DFVTCYSVLKFINANDGSRLHSHDVKYGSGSGQQSVTAVKNSDDINSHWQI--FPALNAKCNRGDAIKCGDKIRLKHLTTGTFLHSHHFTAPLSKQHQEVSAFGSEAESDTGDDWTVICN-GDEWLESEQFKLRHAVTGSYLSLSGQQFGRPIHGQREVVGTDSITGGSAWKVAEGIYIK 200

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Fly
Match: CG11999 (gene:FBgn0037312 transcript:FBtr0078807)

HSP 1 Score: 186.422 bits (472), Expect = 3.479e-58
Identity = 106/221 (47.96%), Postives = 143/221 (64.71%), Query Frame = 2

Query:   41 MEFIIYFSVLFSLYCETNSIQFNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEE 703
            M+ I+  + L  +   +       + VTCGS+LKLLN+++  RLHSHDVKYG GSGQQSVTGV+  +D NS+W +K ++G  + C RG P+ CG TVRL HLST +NLHSHHF SPL+   EVSA+G +GLGD GD W + CS   +W R+ ++ L+H +   YL +SG  YGRPI GQ EI  +++    T W  AEG+F+ P          +SSTH+E
Sbjct:    1 MQHILLLTGLALVGSISRGAATESNVVTCGSILKLLNSDYAFRLHSHDVKYGSGSGQQSVTGVEQKEDVNSHWVIKAQTG--ELCERGEPIACGSTVRLEHLSTKKNLHSHHFSSPLSGEQEVSAYGTDGLGDTGDHWEVVCSN-ENWMRSAHVRLRHIDTGMYLGMSGRSYGRPISGQMEIVGVHKPQHGTRWTTAEGLFIVP--------KEKSSTHDE 210

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Fly
Match: tw (gene:FBgn0086368 transcript:FBtr0070139)

HSP 1 Score: 53.9138 bits (128), Expect = 8.074e-8
Identity = 38/137 (27.74%), Postives = 72/137 (52.55%), Query Frame = 2

Query:  242 DNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNN-FEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHV--------SGERYGRPIEGQAEISC-INRQSRSTEW 622
            D N+ W ++  +       + + ++ G  VRL H++T RNLHSH+  +P+T    +V+ +G+ GLGD  D W +    G   + NE ++   S +  ++H+        SG++  +    Q E+SC  N + ++++W
Sbjct:  364 DENNKWLIRPHNKPGPPKGKVQILRHGDLVRLTHMATRRNLHSHNEPAPMTKKHLQVTGYGELGLGDANDVWRVLIVGG---KVNETVHTVTSRLK-FIHLLQNCALTSSGKQLPKWGFEQQEVSCNPNVRDKNSQW 496

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Fly
Match: tw (gene:FBgn0086368 transcript:FBtr0335403)

HSP 1 Score: 53.9138 bits (128), Expect = 8.074e-8
Identity = 38/137 (27.74%), Postives = 72/137 (52.55%), Query Frame = 2

Query:  242 DNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNN-FEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHV--------SGERYGRPIEGQAEISC-INRQSRSTEW 622
            D N+ W ++  +       + + ++ G  VRL H++T RNLHSH+  +P+T    +V+ +G+ GLGD  D W +    G   + NE ++   S +  ++H+        SG++  +    Q E+SC  N + ++++W
Sbjct:  364 DENNKWLIRPHNKPGPPKGKVQILRHGDLVRLTHMATRRNLHSHNEPAPMTKKHLQVTGYGELGLGDANDVWRVLIVGG---KVNETVHTVTSRLK-FIHLLQNCALTSSGKQLPKWGFEQQEVSCNPNVRDKNSQW 496

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Zebrafish
Match: sdf2 (stromal cell-derived factor 2 [Source:ZFIN;Acc:ZDB-GENE-030131-8823])

HSP 1 Score: 192.971 bits (489), Expect = 1.607e-60
Identity = 109/218 (50.00%), Postives = 150/218 (68.81%), Query Frame = 2

Query:   23 IFH*FRMEFIIYFSVLFSLYCETNSIQFNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVD 676
            +F   ++   +  S +F+L     ++    + VTCGSV+KL+N +HNVRLHSHDV+YG GSGQQSVTGV + +D+NSYW V  R  +   C RG PV+CGQ +RL H++TGRNLHSH+F SPL++N EVSAFG+NG GD  D+W + C+ G+ WQR+E +  +H+   A L V+GE+YGRPI GQ E+  +   S  + W   EG+F+KPS E+ S D
Sbjct:    5 VFLRVQLPLTVLLSCVFTL-----TLCSEMNCVTCGSVVKLINVKHNVRLHSHDVRYGSGSGQQSVTGVTTVEDSNSYWSV--RGTSDHSCHRGTPVRCGQNIRLTHVNTGRNLHSHYFTSPLSSNQEVSAFGENGEGDHLDEWTVLCA-GSIWQRDESVRFQHTATEALLSVTGEQYGRPIHGQREVHGMMVSSSHSYWRTMEGIFIKPS-EAGSRD 213

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Zebrafish
Match: sdf2l1 (stromal cell-derived factor 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-040808-46])

HSP 1 Score: 192.586 bits (488), Expect = 1.669e-60
Identity = 102/205 (49.76%), Postives = 143/205 (69.76%), Query Frame = 2

Query:   41 MEFIIYFSVLFSLYCETNSIQFNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
            M   +   ++  ++    +   +  YVTCGS++KL+N  H+VRLHSHDVKYG GSGQQSVTGVDS+DD NSYW+++ + G+   C RG P++CGQ +R+ H++TGRNLHSHHF SPL+N+ EVSAFG+NG GD+ D W +QCS  T+W R + +  KH+    +L V+GE+YG PI GQ E+  +   ++   W   EGVF++PS
Sbjct:    8 MSVFLDLILVCLVFSPCGARDVDSSYVTCGSLVKLMNTRHSVRLHSHDVKYGSGSGQQSVTGVDSADDANSYWRIRGKPGSI--CQRGAPIRCGQAIRITHMTTGRNLHSHHFSSPLSNHQEVSAFGENGEGDDLDVWNVQCS-ATYWDREDAVRFKHTGTEVFLSVTGEQYGHPIRGQREVHGMPSPNQHNYWKVMEGVFIQPS 209

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Zebrafish
Match: pomt2 (protein-O-mannosyltransferase 2 [Source:NCBI gene;Acc:563878])

HSP 1 Score: 50.8322 bits (120), Expect = 1.026e-6
Identity = 29/79 (36.71%), Postives = 40/79 (50.63%), Query Frame = 2

Query:  242 DNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNN-FEVSAFGDNGLGDEGDDWIIQCSRG 475
            D N+ W VK    +         V+ G  +RL H  T RNLHSH  ++PLT    +V+ +G NG GD  D W ++   G
Sbjct:  390 DYNNLWLVKRLDNSDDLTGSPELVRHGDIIRLEHKETTRNLHSHFHEAPLTKKHLQVTGYGINGSGDVNDLWQVEVCGG 468

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Query:  242 DNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNN-FEVSAFGDNGLGDEGDDWIIQCSRG 475
            D N+ W VK    +         V+ G  +RL H  T RNLHSH  ++PLT    +V+ +G NG GD  D W ++   G
Sbjct:  390 DYNNLWLVKRLDNSDDLTGSPELVRHGDIIRLEHKETTRNLHSHFHEAPLTKKHLQVTGYGINGSGDVNDLWQVEVCGG 468

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Xenopus
Match: rpl13 (ribosomal protein L13 [Source:Xenbase;Acc:XB-GENE-964820])

HSP 1 Score: 198.749 bits (504), Expect = 8.953e-63
Identity = 109/183 (59.56%), Postives = 135/183 (73.77%), Query Frame = 2

Query:  107 NYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
            + +YVTCGSV+KLLN+ HNVRLHSHDVKYG GSGQQSVTGV++SDD NSYW++  R  T   C RG P+KCGQ VRL H++TG+NLH+HHF SPL+NN EVSAFGDNG GD+ D W++QCS  T W+R E +  KH   + YL ++GE+YG PI GQ E+  I   +    W   EGVF+K S
Sbjct:   28 DAEYVTCGSVVKLLNSRHNVRLHSHDVKYGSGSGQQSVTGVEASDDANSYWRI--RGKTDADCSRGEPIKCGQAVRLTHVNTGKNLHTHHFPSPLSNNQEVSAFGDNGEGDDLDAWMVQCSD-TLWEREESVRFKHIGTNVYLTITGEQYGHPIRGQREVHGITNPNAHNYWKVMEGVFLKQS 207

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Xenopus
Match: sdf2l1 (stromal cell-derived factor 2-like protein 1 [Source:NCBI gene;Acc:101732749])

HSP 1 Score: 198.749 bits (504), Expect = 8.953e-63
Identity = 109/183 (59.56%), Postives = 135/183 (73.77%), Query Frame = 2

Query:  107 NYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
            + +YVTCGSV+KLLN+ HNVRLHSHDVKYG GSGQQSVTGV++SDD NSYW++  R  T   C RG P+KCGQ VRL H++TG+NLH+HHF SPL+NN EVSAFGDNG GD+ D W++QCS  T W+R E +  KH   + YL ++GE+YG PI GQ E+  I   +    W   EGVF+K S
Sbjct:   28 DAEYVTCGSVVKLLNSRHNVRLHSHDVKYGSGSGQQSVTGVEASDDANSYWRI--RGKTDADCSRGEPIKCGQAVRLTHVNTGKNLHTHHFPSPLSNNQEVSAFGDNGEGDDLDAWMVQCSD-TLWEREESVRFKHIGTNVYLTITGEQYGHPIRGQREVHGITNPNAHNYWKVMEGVFLKQS 207

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Xenopus
Match: scmh1 (Scm polycomb group protein homolog 1 [Source:Xenbase;Acc:XB-GENE-968911])

HSP 1 Score: 196.438 bits (498), Expect = 7.478e-62
Identity = 105/192 (54.69%), Postives = 142/192 (73.96%), Query Frame = 2

Query:   95 SIQFNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNS 670
            SI      VTCGSV+KLLN +H+VRLHSHDV+YG GSGQQSVTGV S DD NSYW+++ ++ T   C RG+ +KCGQ+VRL H++TGRNLHSHHF SPL+ N EVSAFGD+G GD  DDW + C  G  WQR++ +  +H++   +L V+GE+YGRPI GQ E+  ++  ++++ W   EG+F+KPS +S +
Sbjct:   25 SIASELSVVTCGSVVKLLNIKHSVRLHSHDVRYGSGSGQQSVTGVTSVDDGNSYWRIRGQTSTV--CERGKLIKCGQSVRLTHVNTGRNLHSHHFTSPLSGNQEVSAFGDDGEGDILDDWTVLCG-GEFWQRDDEVRFRHTSTSVFLSVTGEQYGRPINGQREVHGMSYANQNSYWKVMEGIFMKPSEQSRT 213

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Xenopus
Match: POMT2 (protein-O-mannosyltransferase 2 [Source:NCBI gene;Acc:100490100])

HSP 1 Score: 62.003 bits (149), Expect = 3.371e-10
Identity = 44/133 (33.08%), Postives = 64/133 (48.12%), Query Frame = 2

Query:  239 DDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNN-FEVSAFGDNGLGDEGDDWIIQC--SRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISC--INRQSRSTEW 622
             D N+ W +K+ +  +        V+ G  +RL H  T RNLHSH  ++PLT    +V+ +G NG GD  D W I+   SR        +I L H +    L  SG+   R    Q E++C    R++ ST W
Sbjct:  366 KDQNNLWIIKKHNSESDPASPVELVRHGDIIRLEHKMTSRNLHSHQREAPLTKKHLQVTTYGMNGTGDSNDYWRIEVLGSRSKVKVLRSHIRLLHLSTGCLLGSSGKTLPRWGWEQGEVTCSPYVRETPSTLW 498

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Xenopus
Match: POMT2 (protein-O-mannosyltransferase 2 [Source:NCBI gene;Acc:100490100])

HSP 1 Score: 61.2326 bits (147), Expect = 7.263e-10
Identity = 45/135 (33.33%), Postives = 66/135 (48.89%), Query Frame = 2

Query:  242 DNNSYWQVKERSGTTKQCIRGRPVKC---GQTVRLMHLSTGRNLHSHHFKSPLTNN-FEVSAFGDNGLGDEGDDWIIQC--SRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISC--INRQSRSTEW 622
            D N+ W +K+ +  + +     PV+    G  +RL H  T RNLHSH  ++PLT    +V+ +G NG GD  D W I+   SR        +I L H +    L  SG+   R    Q E++C    R++ ST W
Sbjct:  326 DQNNLWIIKKHNSESGERDPASPVELVRHGDIIRLEHKMTSRNLHSHQREAPLTKKHLQVTTYGMNGTGDSNDYWRIEVLGSRSKVKVLRSHIRLLHLSTGCLLGSSGKTLPRWGWEQGEVTCSPYVRETPSTLW 460

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Mouse
Match: Sdf2 (stromal cell derived factor 2 [Source:MGI Symbol;Acc:MGI:108019])

HSP 1 Score: 197.978 bits (502), Expect = 1.797e-62
Identity = 106/183 (57.92%), Postives = 135/183 (73.77%), Query Frame = 2

Query:  107 NYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
            N   VTCGSV+KLLN  HNVRLHSHDV+YG GSGQQSVTGV S DD+NSYW+++ ++ T   C RG P+KCGQ +RL H++TGRNLHSHHF SPL+ N EVSAFG+ G GD  DDW + C+ G +W R+  +  KHS+    L V+GE+YGRPI GQ E+  + + S++  W A EG+F+KPS
Sbjct:   28 NMAVVTCGSVVKLLNTRHNVRLHSHDVRYGSGSGQQSVTGVTSVDDSNSYWRIRGKTATV--CERGTPIKCGQPIRLTHINTGRNLHSHHFTSPLSGNQEVSAFGEEGEGDYLDDWTVLCN-GPYWVRDGEVRFKHSSTDVLLSVTGEQYGRPISGQKEVHGMAQPSQNNYWKAMEGIFMKPS 207

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Mouse
Match: Sdf2l1 (stromal cell-derived factor 2-like 1 [Source:MGI Symbol;Acc:MGI:2149842])

HSP 1 Score: 191.815 bits (486), Expect = 3.787e-60
Identity = 106/196 (54.08%), Postives = 136/196 (69.39%), Query Frame = 2

Query:  119 VTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL 706
            VTCGSVLKLLN  H VRLHSHD+KYG GSGQQSVTGV+ SDD NSYW++  R G+   C RG PV+CGQ VRL H+ TG+NLH+HHF SPL+NN EVSAFG++G GD+ D W ++CS G HW+R   +  +H     +L V+GE+YG PI GQ E+  +   +    W A EG+F+KP        ++ S+ H+EL
Sbjct:   36 VTCGSVLKLLNTHHKVRLHSHDIKYGSGSGQQSVTGVEESDDANSYWRI--RGGSEGGCPRGLPVRCGQAVRLTHVLTGKNLHTHHFPSPLSNNQEVSAFGEDGEGDDLDLWTVRCS-GQHWEREASVRFQHVGTSVFLSVTGEQYGNPIRGQHEVHGMPSANAHNTWKAMEGIFIKPG-------ADLSTGHDEL 221

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Mouse
Match: Pomt2 (protein-O-mannosyltransferase 2 [Source:MGI Symbol;Acc:MGI:2444430])

HSP 1 Score: 60.077 bits (144), Expect = 1.010e-9
Identity = 60/208 (28.85%), Postives = 93/208 (44.71%), Query Frame = 2

Query:  113 DYVTCGSVLKLLNAEHNV-RLHSHDVKYXXXXXXXXXXXXXXX-DDNNSYWQVKERSGTTKQCIRGRPVKC---GQTVRLMHLSTGRNLHSHHFKSPLT-NNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEY----INLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL 706
            +++  GSV+ + N    +  LHSH   Y +G G +          D N+ W +K+ +  T       PV+    G  +RL H  T RNLHSH+ ++PLT  +++V+ +G NG GD  D W I+        R +     I L H      L  SG+   +    Q E++C      +T  I      + P + + S+D  Q S  E L
Sbjct:  335 EHLAYGSVITVKNLRMAIGYLHSHRHLYPEGIGARQQQVTTYLHKDYNNLWIIKKYNANTDPLDPSFPVEFVRHGDIIRLEHKETTRNLHSHYHEAPLTRKHYQVTGYGINGTGDSNDFWRIEVVNRKFGNRIKVLRSRIRLIHLVTGCVLGSSGKILPKWGWEQLEVTCTPYLKETTNSIWNIEEHINPKLPNISLDVLQPSFPEIL 542

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Mouse
Match: Pomt2 (protein-O-mannosyltransferase 2 [Source:MGI Symbol;Acc:MGI:2444430])

HSP 1 Score: 59.3066 bits (142), Expect = 1.918e-9
Identity = 60/208 (28.85%), Postives = 93/208 (44.71%), Query Frame = 2

Query:  113 DYVTCGSVLKLLNAEHNV-RLHSHDVKYXXXXXXXXXXXXXXX-DDNNSYWQVKERSGTTKQCIRGRPVKC---GQTVRLMHLSTGRNLHSHHFKSPLT-NNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEY----INLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL 706
            +++  GSV+ + N    +  LHSH   Y +G G +          D N+ W +K+ +  T       PV+    G  +RL H  T RNLHSH+ ++PLT  +++V+ +G NG GD  D W I+        R +     I L H      L  SG+   +    Q E++C      +T  I      + P + + S+D  Q S  E L
Sbjct:  405 EHLAYGSVITVKNLRMAIGYLHSHRHLYPEGIGARQQQVTTYLHKDYNNLWIIKKYNANTDPLDPSFPVEFVRHGDIIRLEHKETTRNLHSHYHEAPLTRKHYQVTGYGINGTGDSNDFWRIEVVNRKFGNRIKVLRSRIRLIHLVTGCVLGSSGKILPKWGWEQLEVTCTPYLKETTNSIWNIEEHINPKLPNISLDVLQPSFPEIL 612

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BLAST of Stromal cell-derived factor 2 vs. UniProt/SwissProt
Match: sp|Q3T083|SDF2L_BOVIN (Stromal cell-derived factor 2-like protein 1 OS=Bos taurus OX=9913 GN=SDF2L1 PE=2 SV=1)

HSP 1 Score: 199.904 bits (507), Expect = 2.237e-62
Identity = 106/182 (58.24%), Postives = 134/182 (73.63%), Query Frame = 2

Query:  119 VTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVES 664
            VTCGSVLKL N +H VRLHSHD+KYG GSGQQSVTGV++SDD NSYW++  R GT  +C RG PV+CGQ VRL H+ TG+NLH+HHF SPLTNN EVSAFG++G GD+ D W ++CS G HW+R   +  +H     +L V+GE+YG PI GQ E+  +   S   +W A EG+F+KPS E+
Sbjct:   36 VTCGSVLKLFNTQHRVRLHSHDIKYGSGSGQQSVTGVEASDDANSYWRI--RGGTEGECPRGSPVRCGQAVRLTHVLTGKNLHTHHFPSPLTNNQEVSAFGEDGEGDDLDLWTVRCS-GQHWEREAAVRFQHVGTSVFLSVTGEQYGSPIRGQHEVHGMASASAHNKWKAMEGIFIKPSPEA 214

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BLAST of Stromal cell-derived factor 2 vs. UniProt/SwissProt
Match: sp|Q9DCT5|SDF2_MOUSE (Stromal cell-derived factor 2 OS=Mus musculus OX=10090 GN=Sdf2 PE=1 SV=1)

HSP 1 Score: 197.593 bits (501), Expect = 1.383e-61
Identity = 106/183 (57.92%), Postives = 135/183 (73.77%), Query Frame = 2

Query:  107 NYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
            N   VTCGSV+KLLN  HNVRLHSHDV+YG GSGQQSVTGV S DD+NSYW+++ ++ T   C RG P+KCGQ +RL H++TGRNLHSHHF SPL+ N EVSAFG+ G GD  DDW + C+ G +W R+  +  KHS+    L V+GE+YGRPI GQ E+  + + S++  W A EG+F+KPS
Sbjct:   20 NMAVVTCGSVVKLLNTRHNVRLHSHDVRYGSGSGQQSVTGVTSVDDSNSYWRIRGKTATV--CERGTPIKCGQPIRLTHINTGRNLHSHHFTSPLSGNQEVSAFGEEGEGDYLDDWTVLCN-GPYWVRDGEVRFKHSSTDVLLSVTGEQYGRPISGQKEVHGMAQPSQNNYWKAMEGIFMKPS 199

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BLAST of Stromal cell-derived factor 2 vs. UniProt/SwissProt
Match: sp|Q99470|SDF2_HUMAN (Stromal cell-derived factor 2 OS=Homo sapiens OX=9606 GN=SDF2 PE=1 SV=2)

HSP 1 Score: 197.208 bits (500), Expect = 1.737e-61
Identity = 106/179 (59.22%), Postives = 134/179 (74.86%), Query Frame = 2

Query:  119 VTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
            VTCGSV+KLLN  HNVRLHSHDV+YG GSGQQSVTGV S DD+NSYW+++ +S T   C RG P+KCGQ +RL H++TGRNLHSHHF SPL+ N EVSAFG+ G GD  DDW + C+ G +W R+  +  KHS+    L V+GE+YGRPI GQ E+  + + S++  W A EG+F+KPS
Sbjct:   24 VTCGSVVKLLNTRHNVRLHSHDVRYGSGSGQQSVTGVTSVDDSNSYWRIRGKSATV--CERGTPIKCGQPIRLTHVNTGRNLHSHHFTSPLSGNQEVSAFGEEGEGDYLDDWTVLCN-GPYWVRDGEVRFKHSSTEVLLSVTGEQYGRPISGQKEVHGMAQPSQNNYWKAMEGIFMKPS 199

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BLAST of Stromal cell-derived factor 2 vs. UniProt/SwissProt
Match: sp|Q9HCN8|SDF2L_HUMAN (Stromal cell-derived factor 2-like protein 1 OS=Homo sapiens OX=9606 GN=SDF2L1 PE=1 SV=2)

HSP 1 Score: 197.208 bits (500), Expect = 1.956e-61
Identity = 109/198 (55.05%), Postives = 139/198 (70.20%), Query Frame = 2

Query:  113 DYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL 706
            + VTCGSVLKLLN  H VRLHSHD+KYG GSGQQSVTGV++SDD NSYW++  R G+   C RG PV+CGQ VRL H+ TG+NLH+HHF SPL+NN EVSAFG++G GD+ D W ++CS G HW+R   +  +H     +L V+GE+YG PI GQ E+  +   +    W A EG+F+KPSVE        S+ H+EL
Sbjct:   34 ELVTCGSVLKLLNTHHRVRLHSHDIKYGSGSGQQSVTGVEASDDANSYWRI--RGGSEGGCPRGSPVRCGQAVRLTHVLTGKNLHTHHFPSPLSNNQEVSAFGEDGEGDDLDLWTVRCS-GQHWEREAAVRFQHVGTSVFLSVTGEQYGSPIRGQHEVHGMPSANTHNTWKAMEGIFIKPSVEP-------SAGHDEL 221

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BLAST of Stromal cell-derived factor 2 vs. UniProt/SwissProt
Match: sp|Q3SZ45|SDF2_BOVIN (Stromal cell-derived factor 2 OS=Bos taurus OX=9913 GN=SDF2 PE=2 SV=1)

HSP 1 Score: 196.438 bits (498), Expect = 3.402e-61
Identity = 105/183 (57.38%), Postives = 135/183 (73.77%), Query Frame = 2

Query:  107 NYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
            N   VTCGSV+KLLN  HNVRLHSHDV+YG GSGQQSVTGV S DD+NSYW+++ ++ T   C RG P++CGQ +RL H++TGRNLHSHHF SPL+ N EVSAFG+ G GD  DDW + C+ G +W R+  +  KHS+    L V+GE+YGRPI GQ E+  + + S++  W A EG+F+KPS
Sbjct:   20 NLAVVTCGSVVKLLNTRHNVRLHSHDVRYGSGSGQQSVTGVTSVDDSNSYWRIRGKTATV--CERGTPIRCGQPIRLTHVNTGRNLHSHHFTSPLSGNQEVSAFGEEGEGDYLDDWTVLCN-GPYWVRDGEVRFKHSSTEVLLSVTGEQYGRPISGQKEVHGMAQPSQNNYWKAMEGIFMKPS 199

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BLAST of Stromal cell-derived factor 2 vs. TrEMBL
Match: V4CBE7 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_151586 PE=4 SV=1)

HSP 1 Score: 231.106 bits (588), Expect = 2.640e-72
Identity = 126/218 (57.80%), Postives = 161/218 (73.85%), Query Frame = 2

Query:   56 YFSVLFSLYCETNSI-QFNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL 706
            +FSVL   + E  +    NY++VTCGSVLKL+N +H VRLHSHDVKYG GSGQQSVTGVD+SDD+NSYWQ++ ++G T  C RG P+KCGQ++RLMHLST RNLHSHHF+SPL+ N EVSAFGD G+GDEGD+W++ CS   +W R + +  KH     YLHVSG+ +GRPI GQ EIS     +    W AAEG+FVKP+ + N   + ++ TH+EL
Sbjct:    5 WFSVLVLAFFEIIAASDMNYEFVTCGSVLKLMNQQHQVRLHSHDVKYGSGSGQQSVTGVDTSDDHNSYWQIQPKTGAT--CNRGIPIKCGQSIRLMHLSTQRNLHSHHFQSPLSRNLEVSAFGDEGVGDEGDNWVVTCS-SKYWSRRDQVRFKHVVTEHYLHVSGDTFGRPISGQREISAYPNPNSLNYWQAAEGIFVKPAPDPN---TGKTFTHDEL 216

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BLAST of Stromal cell-derived factor 2 vs. TrEMBL
Match: A0A2C9K016 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106074725 PE=4 SV=1)

HSP 1 Score: 231.876 bits (590), Expect = 4.145e-72
Identity = 125/203 (61.58%), Postives = 155/203 (76.35%), Query Frame = 2

Query:   47 FIIYFSVLFSLYCETNSIQFNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
            F+I+  +L S+Y    S +F+YD+VTCGS LK+LN  HN RLHSHDVKYG GSGQQSVTGVDSSDD+NSYWQV  ++G    C RG PVKCGQT+RLMH++T RNLHSHHF+SPL++N EVSAFG+NG GDEGD+W+I C+ G +W RNE +  KH     YLH+SG+ YGRPI GQ EIS  +  S    W AAEG+++KP+
Sbjct:   17 FVIFTFLLDSIY----SSKFDYDFVTCGSALKILNTAHNARLHSHDVKYGSGSGQQSVTGVDSSDDHNSYWQVMAKTGAL--CTRGNPVKCGQTIRLMHVATKRNLHSHHFQSPLSHNLEVSAFGENGEGDEGDNWVIVCN-GKYWSRNERVRFKHVTTEYYLHMSGDTYGRPIHGQREISAYSGISDLNSWQAAEGIYIKPT 212

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BLAST of Stromal cell-derived factor 2 vs. TrEMBL
Match: A0A210R482 (Stromal cell-derived factor 2 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT23836 PE=4 SV=1)

HSP 1 Score: 225.713 bits (574), Expect = 2.662e-70
Identity = 126/201 (62.69%), Postives = 151/201 (75.12%), Query Frame = 2

Query:  104 FNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL 706
            F+YDYVTCGS LKLLN  HNVRLHSHDVKYG GSGQQSVT VDSS+D+NSYWQV+ ++G    C RG PVKCGQT+RLMHL+T RNLHSHHF+SPL++N EVSAFG+NG GDEGD+W+I C+ G +W R E + +K+     YLHVSG+ YGRPI GQ EIS     S    W A EG+F+KP+ E +S     S  H+EL
Sbjct:    9 FDYDYVTCGSSLKLLNNHHNVRLHSHDVKYGSGSGQQSVTAVDSSEDHNSYWQVRGKTGIG--CTRGEPVKCGQTLRLMHLNTRRNLHSHHFQSPLSHNLEVSAFGENGEGDEGDNWVIVCA-GKYWSRKEKVKIKNVVTEYYLHVSGDTYGRPIHGQREISAYPSPSELNYWQAKEGIFIKPTSEPSS-----SGYHDEL 201

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BLAST of Stromal cell-derived factor 2 vs. TrEMBL
Match: A0A2C9K026 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106074725 PE=4 SV=1)

HSP 1 Score: 224.942 bits (572), Expect = 7.983e-70
Identity = 119/185 (64.32%), Postives = 145/185 (78.38%), Query Frame = 2

Query:  101 QFNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
            +F+YD+VTCGS LK+LN  HN RLHSHDVKYG GSGQQSVTGVDSSDD+NSYWQV  ++G    C RG PVKCGQT+RLMH++T RNLHSHHF+SPL++N EVSAFG+NG GDEGD+W+I C+ G +W RNE +  KH     YLH+SG+ YGRPI GQ EIS  +  S    W AAEG+++KP+
Sbjct:    8 EFDYDFVTCGSALKILNTAHNARLHSHDVKYGSGSGQQSVTGVDSSDDHNSYWQVMAKTGAL--CTRGNPVKCGQTIRLMHVATKRNLHSHHFQSPLSHNLEVSAFGENGEGDEGDNWVIVCN-GKYWSRNERVRFKHVTTEYYLHMSGDTYGRPIHGQREISAYSGISDLNSWQAAEGIYIKPT 189

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BLAST of Stromal cell-derived factor 2 vs. TrEMBL
Match: A0A0L8GHQ5 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22033425mg PE=4 SV=1)

HSP 1 Score: 223.787 bits (569), Expect = 2.103e-69
Identity = 117/202 (57.92%), Postives = 152/202 (75.25%), Query Frame = 2

Query:   65 VLFSLYCETNSIQFNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNS 670
            +LFS +  T + QF+Y YVTCGS LKLLN  H VRLHSHD+KYG GSGQQSVT V+SSDD+NSYWQ++ + GT+  C RG PVKC QT++LMH++T RNLH HHF+SPL+NN EVSAFG++G+GD GDDW + C  G +W R E I LK+    +YLHV+G+ YGRPI+GQ E+S  +  +    W A EG+F+KP++  +S
Sbjct:   12 LLFSAFTLTETEQFHYKYVTCGSTLKLLNPYHKVRLHSHDIKYGSGSGQQSVTAVESSDDHNSYWQIQPKPGTS--CFRGVPVKCDQTIQLMHVATRRNLHGHHFRSPLSNNLEVSAFGEDGVGDAGDDWTVICKTG-NWSREERIRLKNVVTGSYLHVNGDVYGRPIQGQREVSAHDHPNEKNYWQAGEGIFIKPALPIHS 210

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BLAST of Stromal cell-derived factor 2 vs. Ensembl Cavefish
Match: sdf2 (stromal cell derived factor 2 [Source:NCBI gene;Acc:103045583])

HSP 1 Score: 202.986 bits (515), Expect = 1.424e-64
Identity = 111/201 (55.22%), Postives = 144/201 (71.64%), Query Frame = 2

Query:   53 IYFSVLFSLYCETNSIQFNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
            ++ SVL S  C   S+     +VTCGSV+KLLN +HNVRLHSHDV+YG GSGQQSVTGV + +D+NSYW V+  SG    C RG PVKCGQ +RL H++TGRNLHSH+F SPL++N EVSAFG+ G GD  D+W + C  G+ WQR+E +  +H+   A L V+GE+YGRPI GQ E+  +   S+ + W A EG+F+KPS
Sbjct:   16 LWVSVLLSSMCHF-SLGSEIRFVTCGSVVKLLNVKHNVRLHSHDVRYGSGSGQQSVTGVTTVEDSNSYWSVRGTSGAV--CHRGTPVKCGQNIRLTHVNTGRNLHSHYFASPLSSNQEVSAFGEEGEGDNLDEWTVLCG-GSMWQRDESVRFRHTATDALLSVTGEQYGRPIHGQREVHAMTSTSQHSYWKAMEGIFMKPS 212

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Cavefish
Match: sdf2 (stromal cell derived factor 2 [Source:NCBI gene;Acc:103045583])

HSP 1 Score: 200.29 bits (508), Expect = 1.236e-63
Identity = 110/203 (54.19%), Postives = 142/203 (69.95%), Query Frame = 2

Query:   47 FIIYFSVLFSLYCETNSIQFNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
              I   +L S  C   S+     +VTCGSV+KLLN +HNVRLHSHDV+YG GSGQQSVTGV + +D+NSYW V+  SG    C RG PVKCGQ +RL H++TGRNLHSH+F SPL++N EVSAFG+ G GD  D+W + C  G+ WQR+E +  +H+   A L V+GE+YGRPI GQ E+  +   S+ + W A EG+F+KPS
Sbjct:    1 MFILVLILLSSMCHF-SLGSEIRFVTCGSVVKLLNVKHNVRLHSHDVRYGSGSGQQSVTGVTTVEDSNSYWSVRGTSGAV--CHRGTPVKCGQNIRLTHVNTGRNLHSHYFASPLSSNQEVSAFGEEGEGDNLDEWTVLCG-GSMWQRDESVRFRHTATDALLSVTGEQYGRPIHGQREVHAMTSTSQHSYWKAMEGIFMKPS 199

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Cavefish
Match: sdf2l1 (stromal cell derived factor 2 like 1 [Source:NCBI gene;Acc:103043821])

HSP 1 Score: 198.749 bits (504), Expect = 5.567e-63
Identity = 105/182 (57.69%), Postives = 135/182 (74.18%), Query Frame = 2

Query:  116 YVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVE 661
            YVTCGS++KLLN  HNVRLHSHDVKYG GSGQQSVTGVD++DD NSYW+++ +   T  C RG P+KCGQ +R  H+ TGRNLHSHHF SPL+NN EVSAFG+NG GD+ D W +QCS GT+W+R + +  KH     +L ++GE+YG PI GQ E+  ++  + +  W   EGVF++PS E
Sbjct:   32 YVTCGSLVKLLNTRHNVRLHSHDVKYGSGSGQQSVTGVDTADDANSYWRIRGKPNET--CQRGIPIKCGQAIRFTHMKTGRNLHSHHFSSPLSNNQEVSAFGENGEGDDLDVWAVQCS-GTYWEREDAVRFKHVGTSVFLSITGEQYGHPIRGQREVHGMHSANHNNYWKVMEGVFIQPSNE 210

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Cavefish
Match: sdf2l1 (stromal cell derived factor 2 like 1 [Source:NCBI gene;Acc:103043821])

HSP 1 Score: 197.978 bits (502), Expect = 1.030e-62
Identity = 110/218 (50.46%), Postives = 147/218 (67.43%), Query Frame = 2

Query:   53 IYFSVLFSLYCETNSIQFNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL 706
            +   +LF       + + +  YVTCGS++KLLN  HNVRLHSHDVKYG GSGQQSVTGVD++DD NSYW+++ +   T  C RG P+KCGQ +R  H+ TGRNLHSHHF SPL+NN EVSAFG+NG GD+ D W +QCS GT+W+R + +  KH     +L ++GE+YG PI GQ E+  ++  + +  W   EGVF++P        SN+   H+EL
Sbjct:    3 VLILMLFLCLWYIGAREPDTAYVTCGSLVKLLNTRHNVRLHSHDVKYGSGSGQQSVTGVDTADDANSYWRIRGKPNET--CQRGIPIKCGQAIRFTHMKTGRNLHSHHFSSPLSNNQEVSAFGENGEGDDLDVWAVQCS-GTYWEREDAVRFKHVGTSVFLSITGEQYGHPIRGQREVHGMHSANHNNYWKVMEGVFIQP--------SNEPLYHDEL 209

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Cavefish
Match: sdf2 (stromal cell derived factor 2 [Source:NCBI gene;Acc:103045583])

HSP 1 Score: 198.364 bits (503), Expect = 1.136e-62
Identity = 105/180 (58.33%), Postives = 135/180 (75.00%), Query Frame = 2

Query:  116 YVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPS 655
            +VTCGSV+KLLN +HNVRLHSHDV+YG GSGQQSVTGV + +D+NSYW V+  SG    C RG PVKCGQ +RL H++TGRNLHSH+F SPL++N EVSAFG+ G GD  D+W + C  G+ WQR+E +  +H+   A L V+GE+YGRPI GQ E+  +   S+ + W A EG+F+KPS
Sbjct:   37 FVTCGSVVKLLNVKHNVRLHSHDVRYGSGSGQQSVTGVTTVEDSNSYWSVRGTSGAV--CHRGTPVKCGQNIRLTHVNTGRNLHSHYFASPLSSNQEVSAFGEEGEGDNLDEWTVLCG-GSMWQRDESVRFRHTATDALLSVTGEQYGRPIHGQREVHAMTSTSQHSYWKAMEGIFMKPS 213

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Sea Lamprey
Match: pomt2 (protein-O-mannosyltransferase 2 [Source:NCBI gene;Acc:563878])

HSP 1 Score: 55.4546 bits (132), Expect = 5.477e-9
Identity = 41/125 (32.80%), Postives = 61/125 (48.80%), Query Frame = 2

Query:  113 DYVTCGSVLKLLNAE-HNVRLHSHDVKYXXXXXXXXXXXXXXX-DDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNN-FEVSAFGDNGLGDEGDDWIIQCSRGT 478
            +Y+  GSV+ L N       LHSH   Y +G G         +  D N+ W VK+             V+ G  +RL H+ T RNLHSH  ++PL++   +V+ +G+NG GD  D W ++   G 
Sbjct:  225 EYIAYGSVVTLKNVRTAGGYLHSHWHLYPEGVGAMQQQITAYTHKDQNNMWLVKKHDRNPSDSDPPELVQNGDVIRLEHVVTKRNLHSHKERAPLSSKHLQVTGYGENGTGDSNDLWRVEVVGGA 349

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Yeast
Match: PMT6 (Protein O-mannosyltransferase; transfers mannose from dolichyl phosphate-D-mannose to protein serine/threonine residues of secretory proteins; reaction is essential for cell wall rigidity; member of a family of mannosyltransferases [Source:SGD;Acc:S000003431])

HSP 1 Score: 63.929 bits (154), Expect = 7.263e-12
Identity = 43/123 (34.96%), Postives = 59/123 (47.97%), Query Frame = 2

Query:  308 PVKCGQTVRLMHLSTGRNLHSHHFKSPLT-NNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYIN--------------LKHSNIHAYLHVSGERYGRPIEGQAEISCIN---RQSRSTEW 622
            P+  G  VRL H +TG NLHSH   S ++  N+EVS +G   +GDE DDWI++  +        Y N              L+H  +  YL  +G  Y      QAEI C +   R+ +ST W
Sbjct:  413 PITDGVEVRLSHKNTGSNLHSHDVPSHVSRGNYEVSGYGSQSVGDEKDDWIVEIVKQMDSPNPVYSNENSTILHPVSTFFRLRHKVLGCYLASTGLTYPAWGFKQAEIVCKDSWSRRDKSTWW 535

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Yeast
Match: PMT3 (Protein O-mannosyltransferase; transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt5p, can instead interact with Pmt1p in some conditions; antifungal drug target; PMT3 has a paralog, PMT2, that arose from the whole genome duplication [Source:SGD;Acc:S000005848])

HSP 1 Score: 61.6178 bits (148), Expect = 3.876e-11
Identity = 37/108 (34.26%), Postives = 58/108 (53.70%), Query Frame = 2

Query:  311 VKCGQTVRLMHLSTGRNLHSHHFKSPLTNN-FEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYIN-------LKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSR 610
            VK G+  RLMH  TG+NLH+H   +P++ + +EVSA+GD  LGD  D+WII+       +    ++       +K+S +  YL  SG+        Q E+ C+   S+
Sbjct:  404 VKGGEMYRLMHRLTGKNLHTHEVPAPISKSEYEVSAYGDVDLGDYKDNWIIEIVEQVGEEDPTLLHPLSTSFRIKNSILGCYLAQSGKHLPEWGFRQGEVVCLKHASK 511

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Yeast
Match: PMT2 (Protein O-mannosyltransferase of the ER membrane; transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; involved in ER quality control; acts in a complex with Pmt1p, can instead interact with Pmt5p; antifungal drug target; PMT2 has a paralog, PMT3, that arose from the whole genome duplication [Source:SGD;Acc:S000000021])

HSP 1 Score: 56.9954 bits (136), Expect = 1.312e-9
Identity = 41/101 (40.59%), Postives = 59/101 (58.42%), Query Frame = 2

Query:  170 LHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKER--SGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNN-FEVSAFGDNGLGDEGDDWIIQ 463
            LHSH   Y  GS QQ VT     D NN ++  +ER     ++       +K G + RL+H STGRNLH+H   +P++   +EVS +GDN +GD  D+W+I+
Sbjct:  361 LHSHIQTYPDGSNQQQVTCYGYKDANNEWFFNRERGLPSWSENETDIEYLKPGTSYRLVHKSTGRNLHTHPVAAPVSKTQWEVSGYGDNVVGDNKDNWVIE 461

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Yeast
Match: PMT5 (Protein O-mannosyltransferase; transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt3p, can instead interact with Pmt2p in some conditions; target for new antifungals [Source:SGD;Acc:S000002251])

HSP 1 Score: 46.595 bits (109), Expect = 2.860e-6
Identity = 51/155 (32.90%), Postives = 66/155 (42.58%), Query Frame = 2

Query:  170 LHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNF----EVSAFGDNGL-GDEGDDWIIQC--SRGTHWQRNEYI-------NLKHSNIHAYLHVSGERYGRPIEGQAEISC 592
            LHSH   Y  GS QQ VT     D NN  W ++      +     + +  G  ++L  L  G  LHSH  K P++ N     EVS +G  G  GD  DDWII+    R       E+I        LKH     YL    E+      GQ E++C
Sbjct:  341 LHSHLHNYPAGSMQQQVTLYPHIDQNNK-WIIELAEHPNENVTSFQNLTDGTIIKLRQLKNGCRLHSHDHKPPVSQNADWQKEVSCYGYEGFEGDINDDWIIEIDKKRSEPGPAQEHIRAIETKFRLKHYLTGCYLFSHPEKLPEWGFGQQEVTC 494

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Nematostella
Match: EDO45492 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSN3])

HSP 1 Score: 196.823 bits (499), Expect = 1.375e-62
Identity = 102/182 (56.04%), Postives = 135/182 (74.18%), Query Frame = 2

Query:  107 NYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKP 652
            ++ YVTCGSV+KLLN +HNVRLHSH+VKYG GSGQQSVTGV S DD NSYW +K  +   K C RG P+KC +T+RL HL+T RNLHSHHF+SP+++N EVSAFG+ G GD  DDW++ CS+  +W+R + +  +H     YLH++G+++GRPI GQ E+S  N    S EW   EG+++KP
Sbjct:   41 DFKYVTCGSVVKLLNTKHNVRLHSHEVKYGSGSGQQSVTGVLSVDDGNSYWVIKGEN--DKPCKRGEPIKCDETIRLQHLATKRNLHSHHFQSPISHNQEVSAFGEGGNGDNLDDWVVVCSK-KNWERKDTVRFRHKITEMYLHITGDQFGRPIHGQREVSGFNYPDVSNEWKTMEGIYIKP 219

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Nematostella
Match: EDO43071 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZY4])

HSP 1 Score: 54.299 bits (129), Expect = 2.322e-8
Identity = 41/123 (33.33%), Postives = 62/123 (50.41%), Query Frame = 2

Query:  239 DDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTN-NFEVSAFGDNGLGDEGDDW---IIQCSRGTHWQRNEYI-NLKHSNIHAYLHVSGERYGRPIEGQAEISC 592
            DDNN +  +K+             VK G  +RL H +T RN+HSH+ K+PLT  + +V+A+G+ G GD  D W   I+  S   H +    I  L H N+   LH+  +   +    Q E++C
Sbjct:  328 DDNNKF-LIKKAYEDYDANEPVEFVKNGDWIRLEHAATKRNIHSHNEKAPLTKHHMQVTAYGEEGKGDANDFWRVEIVSGSPDNHVKTVRTIFRLIHVNLDCALHMGSKTLPKWGWEQLEVTC 449

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Medaka
Match: sdf2 (stromal cell-derived factor 2 [Source:NCBI gene;Acc:101163102])

HSP 1 Score: 199.904 bits (507), Expect = 2.919e-63
Identity = 113/220 (51.36%), Postives = 149/220 (67.73%), Query Frame = 2

Query:   47 FIIYFSVLFSLYCETNSIQFNYDYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL 706
            F+    V+FS  C+  S+     +VTCGSV+KLLN +HNVRLHSHDV+YG GSGQQSVTGV + +D+NSYW +  R      C RG PVKCGQ +RL H++TGRNLHSH+F SPL++N EVSAFG+ G GD  D+W + C+ G+ W+R E I  +H      L V+GE+YGRPI GQ E+  +   S+ + W A EG+F+KPS E ++   + S TH E 
Sbjct:   12 FLSTLFVVFSCICQL-SLGTELSFVTCGSVVKLLNVKHNVRLHSHDVRYGSGSGQQSVTGVTTVEDSNSYWSI--RGTRDALCQRGTPVKCGQAIRLTHVNTGRNLHSHYFASPLSSNQEVSAFGEEGEGDHLDEWTVHCA-GSVWKREEAIRFRHKATDVLLSVTGEQYGRPIHGQMEVHGMASPSQHSLWKAMEGIFMKPS-EISAGGQDYSHTHTEF 226

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Medaka
Match: sdf2l1 (stromal cell derived factor 2 like 1 [Source:NCBI gene;Acc:101175244])

HSP 1 Score: 198.364 bits (503), Expect = 8.799e-63
Identity = 104/183 (56.83%), Postives = 136/183 (74.32%), Query Frame = 2

Query:  113 DYVTCGSVLKLLNAEHNVRLHSHDVKYXXXXXXXXXXXXXXXDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVE 661
            ++VTCGS++KLLN  HNVRLHSHDVKYG GSGQQSVTGV++++D NSYWQ+  R    + C RG P+KCGQ VR+ H+ TGRNLHSHHF SPL+NN EVSAFG+NG GD+ D W +QC  G  W+R+E +  KH     +L V+GE+YG PI GQ E+  ++  ++ + W   EGVF++PS+E
Sbjct:   33 NHVTCGSLVKLLNTRHNVRLHSHDVKYGSGSGQQSVTGVETAEDANSYWQI--RGKPDRPCQRGSPIKCGQAVRITHMKTGRNLHSHHFSSPLSNNQEVSAFGENGQGDDLDVWTVQCD-GVLWERDEAVRFKHVGTEVFLSVTGEQYGHPIRGQREVHGMSSPTQHSWWRTMEGVFIQPSME 212

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Medaka
Match: pomt2 (protein O-mannosyltransferase 2 [Source:NCBI gene;Acc:101167160])

HSP 1 Score: 58.5362 bits (140), Expect = 3.081e-9
Identity = 40/137 (29.20%), Postives = 67/137 (48.91%), Query Frame = 2

Query:  242 DNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNN-FEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIH-------AYLHVSGERYGRPIEGQAEISCIN--RQSRSTEW 622
            D N+ W V++      +      V+ G  +RL H  T RNLH+H  ++PLT   F+V+ +G NG GD  D W ++   G   QR + + +  S +          L+ SG+   +    Q E++C    ++S S++W
Sbjct:  387 DYNNLWLVRKPEENDSESRTPVLVRHGDIIRLEHKETTRNLHAHRQEAPLTKKHFQVTGYGINGTGDSNDLWRVEVCGG---QRGDLVKVLRSKVRFLHKATGCVLYSSGKTLPKWGWEQVEVTCSPYLKESPSSQW 520

[Close]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Medaka
Match: pomt2 (protein O-mannosyltransferase 2 [Source:NCBI gene;Acc:101167160])

HSP 1 Score: 58.5362 bits (140), Expect = 3.084e-9
Identity = 40/137 (29.20%), Postives = 67/137 (48.91%), Query Frame = 2

Query:  242 DNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLMHLSTGRNLHSHHFKSPLTNN-FEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIH-------AYLHVSGERYGRPIEGQAEISCIN--RQSRSTEW 622
            D N+ W V++      +      V+ G  +RL H  T RNLH+H  ++PLT   F+V+ +G NG GD  D W ++   G   QR + + +  S +          L+ SG+   +    Q E++C    ++S S++W
Sbjct:  387 DYNNLWLVRKPEENDSESRTPVLVRHGDIIRLEHKETTRNLHAHRQEAPLTKKHFQVTGYGINGTGDSNDLWRVEVCGG---QRGDLVKVLRSKVRFLHKATGCVLYSSGKTLPKWGWEQVEVTCSPYLKESPSSQW 520

[Close]

BLAST of Stromal cell-derived factor 2 vs. Planmine SMEST
Match: SMESG000076890.1 (SMESG000076890.1)

HSP 1 Score: 257.684 bits (657), Expect = 1.495e-87
Identity = 123/123 (100.00%), Postives = 123/123 (100.00%), Query Frame = 2

Query:  338 MHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL 706
            MHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL
Sbjct:    1 MHLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQRNEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGVFVKPSVESNSVDSNQSSTHEEL 123

The following BLAST results are available for this feature:

BLAST of Stromal cell-derived factor 2 vs. Ensembl Human
BLAST of Stromal cell-derived factor 2 vs. Ensembl Celegans
BLAST of Stromal cell-derived factor 2 vs. Ensembl Fly
BLAST of Stromal cell-derived factor 2 vs. Ensembl Zebrafish
BLAST of Stromal cell-derived factor 2 vs. Ensembl Xenopus
BLAST of Stromal cell-derived factor 2 vs. Ensembl Mouse
BLAST of Stromal cell-derived factor 2 vs. UniProt/SwissProt
BLAST of Stromal cell-derived factor 2 vs. TrEMBL
BLAST of Stromal cell-derived factor 2 vs. Ensembl Cavefish
BLAST of Stromal cell-derived factor 2 vs. Ensembl Sea Lamprey
BLAST of Stromal cell-derived factor 2 vs. Ensembl Yeast
BLAST of Stromal cell-derived factor 2 vs. Ensembl Nematostella
BLAST of Stromal cell-derived factor 2 vs. Ensembl Medaka
BLAST of Stromal cell-derived factor 2 vs. Planmine SMEST

BLAST of Stromal cell-derived factor 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4


Match Name	E-value	Identity	Description
SDF2	3.616e-62	59.22	stromal cell derived factor 2 [Source:HGNC Symbol;...	[more]
SDF2L1	4.073e-62	55.05	stromal cell derived factor 2 like 1 [Source:HGNC ...	[more]
SDF2	6.169e-32	70.21	stromal cell derived factor 2 [Source:HGNC Symbol;...	[more]
POMT2	1.438e-7	27.61	protein O-mannosyltransferase 2 [Source:HGNC Symbo...	[more]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
R12E2.13	1.901e-46	49.44	pep chromosome:WBcel235:I:4177305:4178447:-1 gene:...	[more]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3


Match Name	E-value	Identity	Description
CG11999	3.479e-58	47.96	gene:FBgn0037312 transcript:FBtr0078807	[more]
tw	8.074e-8	27.74	gene:FBgn0086368 transcript:FBtr0070139	[more]
tw	8.074e-8	27.74	gene:FBgn0086368 transcript:FBtr0335403	[more]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
sdf2	1.607e-60	50.00	stromal cell-derived factor 2 [Source:ZFIN;Acc:ZDB...	[more]
sdf2l1	1.669e-60	49.76	stromal cell-derived factor 2-like 1 [Source:ZFIN;...	[more]
pomt2	1.026e-6	36.71	protein-O-mannosyltransferase 2 [Source:NCBI gene;...	[more]
pomt2	1.026e-6	36.71	protein-O-mannosyltransferase 2 [Source:NCBI gene;...	[more]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rpl13	8.953e-63	59.56	ribosomal protein L13 [Source:Xenbase;Acc:XB-GENE-...	[more]
sdf2l1	8.953e-63	59.56	stromal cell-derived factor 2-like protein 1 [Sour...	[more]
scmh1	7.478e-62	54.69	Scm polycomb group protein homolog 1 [Source:Xenba...	[more]
POMT2	3.371e-10	33.08	protein-O-mannosyltransferase 2 [Source:NCBI gene;...	[more]
POMT2	7.263e-10	33.33	protein-O-mannosyltransferase 2 [Source:NCBI gene;...	[more]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Sdf2	1.797e-62	57.92	stromal cell derived factor 2 [Source:MGI Symbol;A...	[more]
Sdf2l1	3.787e-60	54.08	stromal cell-derived factor 2-like 1 [Source:MGI S...	[more]
Pomt2	1.010e-9	28.85	protein-O-mannosyltransferase 2 [Source:MGI Symbol...	[more]
Pomt2	1.918e-9	28.85	protein-O-mannosyltransferase 2 [Source:MGI Symbol...	[more]

BLAST of Stromal cell-derived factor 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q3T083\|SDF2L_BOVIN	2.237e-62	58.24	Stromal cell-derived factor 2-like protein 1 OS=Bo...	[more]
sp\|Q9DCT5\|SDF2_MOUSE	1.383e-61	57.92	Stromal cell-derived factor 2 OS=Mus musculus OX=1...	[more]
sp\|Q99470\|SDF2_HUMAN	1.737e-61	59.22	Stromal cell-derived factor 2 OS=Homo sapiens OX=9...	[more]
sp\|Q9HCN8\|SDF2L_HUMAN	1.956e-61	55.05	Stromal cell-derived factor 2-like protein 1 OS=Ho...	[more]
sp\|Q3SZ45\|SDF2_BOVIN	3.402e-61	57.38	Stromal cell-derived factor 2 OS=Bos taurus OX=991...	[more]

BLAST of Stromal cell-derived factor 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
V4CBE7	2.640e-72	57.80	Uncharacterized protein OS=Lottia gigantea OX=2251...	[more]
A0A2C9K016	4.145e-72	61.58	Uncharacterized protein OS=Biomphalaria glabrata O...	[more]
A0A210R482	2.662e-70	62.69	Stromal cell-derived factor 2 OS=Mizuhopecten yess...	[more]
A0A2C9K026	7.983e-70	64.32	Uncharacterized protein OS=Biomphalaria glabrata O...	[more]
A0A0L8GHQ5	2.103e-69	57.92	Uncharacterized protein OS=Octopus bimaculoides OX...	[more]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sdf2	1.424e-64	55.22	stromal cell derived factor 2 [Source:NCBI gene;Ac...	[more]
sdf2	1.236e-63	54.19	stromal cell derived factor 2 [Source:NCBI gene;Ac...	[more]
sdf2l1	5.567e-63	57.69	stromal cell derived factor 2 like 1 [Source:NCBI ...	[more]
sdf2l1	1.030e-62	50.46	stromal cell derived factor 2 like 1 [Source:NCBI ...	[more]
sdf2	1.136e-62	58.33	stromal cell derived factor 2 [Source:NCBI gene;Ac...	[more]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
pomt2	5.477e-9	32.80	protein-O-mannosyltransferase 2 [Source:NCBI gene;...	[more]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4


Match Name	E-value	Identity	Description
PMT6	7.263e-12	34.96	Protein O-mannosyltransferase; transfers mannose f...	[more]
PMT3	3.876e-11	34.26	Protein O-mannosyltransferase; transfers mannose r...	[more]
PMT2	1.312e-9	40.59	Protein O-mannosyltransferase of the ER membrane; ...	[more]
PMT5	2.860e-6	32.90	Protein O-mannosyltransferase; transfers mannose r...	[more]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO45492	1.375e-62	56.04	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43071	2.322e-8	33.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Stromal cell-derived factor 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
sdf2	2.919e-63	51.36	stromal cell-derived factor 2 [Source:NCBI gene;Ac...	[more]
sdf2l1	8.799e-63	56.83	stromal cell derived factor 2 like 1 [Source:NCBI ...	[more]
pomt2	3.081e-9	29.20	protein O-mannosyltransferase 2 [Source:NCBI gene;...	[more]
pomt2	3.084e-9	29.20	protein O-mannosyltransferase 2 [Source:NCBI gene;...	[more]

BLAST of Stromal cell-derived factor 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000076890.1	1.495e-87	100.00	SMESG000076890.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30000463 ID=SMED30000463|Name=Stromal cell-derived factor 2|organism=Schmidtea mediterranea sexual|type=transcript|length=887bp
CTTTGTTTAAATATCCACACGTATATTTCACTAATTTAGAATGGAATTTA
TAATTTATTTTAGTGTTTTATTTTCATTATACTGTGAGACAAATTCTATA
CAATTTAATTATGACTATGTTACATGTGGGTCTGTATTAAAGCTTCTGAA
TGCTGAACATAATGTTCGTTTGCATTCTCATGATGTTAAGTATGGACAAG
GAAGTGGCCAGCAATCTGTTACTGGTGTAGATTCTTCTGATGATAACAAT
AGTTATTGGCAGGTTAAAGAAAGAAGTGGTACGACTAAGCAATGCATAAG
AGGAAGACCTGTTAAATGCGGACAAACAGTGCGATTAATGCATTTGTCGA
CAGGAAGAAATTTACACAGTCACCATTTTAAATCTCCATTAACCAACAAT
TTTGAAGTGTCGGCATTTGGAGACAATGGGCTAGGAGATGAAGGCGATGA
TTGGATAATCCAATGTTCCCGTGGAACTCACTGGCAAAGGAATGAATACA
TCAATTTGAAGCACTCAAATATCCATGCATATCTTCACGTGAGCGGGGAA
AGATATGGCCGACCAATTGAAGGCCAGGCAGAGATTTCCTGCATCAATCG
TCAATCGCGATCGACTGAATGGATCGCAGCCGAGGGAGTATTTGTCAAGC
CTTCAGTGGAATCCAATTCAGTCGACTCCAACCAATCATCTACTCATGAG
GAATTGTAATCTTACACAGATATGGCATATTTTATCCGCATTTTTGCTTC
TACTTGTAAAATGTTAGCAGTTTCAATTTTTCCTTATTAATAATAAATAA
TTATAATAATCAGTAGCGAGGCAAATTTAATATTTTAAAATTTCTTTTCT
TTATTGTTGTAATAAATGTTGGTTTTCCTGAAAAAAA

protein sequence of SMED30000463-orf-1

>SMED30000463-orf-1 ID=SMED30000463-orf-1|Name=SMED30000463-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=223bp
MEFIIYFSVLFSLYCETNSIQFNYDYVTCGSVLKLLNAEHNVRLHSHDVK
YGQGSGQQSVTGVDSSDDNNSYWQVKERSGTTKQCIRGRPVKCGQTVRLM
HLSTGRNLHSHHFKSPLTNNFEVSAFGDNGLGDEGDDWIIQCSRGTHWQR
NEYINLKHSNIHAYLHVSGERYGRPIEGQAEISCINRQSRSTEWIAAEGV
FVKPSVESNSVDSNQSSTHEEL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036300	MIR_dom_sf
IPR016093	MIR_motif

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR016093	MIR motif	SMART	SM00472	mir_2	coord: 145..199 e-value: 1.4 score: 15.0 coord: 88..143 e-value: 7.1E-14 score: 62.1 coord: 24..78 e-value: 1.1E-8 score: 44.8
IPR016093	MIR motif	PFAM	PF02815	MIR	coord: 36..134 e-value: 2.3E-12 score: 47.1
IPR016093	MIR motif	PROSITE	PS50919	MIR	coord: 145..199 score: 8.186
IPR016093	MIR motif	PROSITE	PS50919	MIR	coord: 88..143 score: 13.742
IPR016093	MIR motif	PROSITE	PS50919	MIR	coord: 24..78 score: 11.857
None	No IPR available	GENE3D	G3DSA:2.80.10.50		coord: 22..208 e-value: 4.6E-58 score: 197.9
None	No IPR available	PANTHER	PTHR46809	FAMILY NOT NAMED	coord: 8..210
None	No IPR available	PANTHER	PTHR46809:SF1		coord: 8..210
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..19 score: 0.488
IPR036300	Mir domain superfamily	SUPERFAMILY	SSF82109	MIR domain	coord: 25..199