Ras-related C3 botulinum toxin substrate 1

Overview
NameRas-related C3 botulinum toxin substrate 1
Smed IDSMED30000430
Length (bp)743
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ras-related C3 botulinum toxin substrate 1 (SMED30000430) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras-related C3 botulinum toxin substrate 1 (SMED30000430) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras-related C3 botulinum toxin substrate 1 (SMED30000430) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras-related C3 botulinum toxin substrate 1 (SMED30000430) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30000430

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30000430h1SMcG0022020 Contig2853GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30000430h1SMcG0022020 Contig2853GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30000430h1SMcG0022020 dd_Smed_v4_3362_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
tail regionSMED30000430h1SMcG0022020 dd_Smed_v6_3362_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Human
Match: RAC1 (Rac family small GTPase 1 [Source:HGNC Symbol;Acc:HGNC:9801])

HSP 1 Score: 263.077 bits (671), Expect = 4.893e-89
Identity = 124/193 (64.25%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Human
Match: RAC2 (Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802])

HSP 1 Score: 257.684 bits (657), Expect = 5.566e-87
Identity = 121/193 (62.69%), Postives = 152/193 (78.76%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  S+ NV+ KWF EV H+  +TPIILVGTKLDLRD+KD  E  K +   +P+TY QGLAL +EI +VKY+ECSA TQ  LK VF+EA+R VL     R++ + CS L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKL-APITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Human
Match: RAC3 (Rac family small GTPase 3 [Source:HGNC Symbol;Acc:HGNC:9803])

HSP 1 Score: 251.521 bits (641), Expect = 1.404e-84
Identity = 116/178 (65.17%), Postives = 147/178 (82.58%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVL 599
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  +TPI+LVGTKLDLRD+KD  E  + +   +P+TY QGLA+ +EIG+VKY+ECSA TQ  LK VF+EA+R VL
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKL-APITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVL 177
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Human
Match: RAC1 (Rac family small GTPase 1 [Source:HGNC Symbol;Acc:HGNC:9801])

HSP 1 Score: 251.521 bits (641), Expect = 3.231e-84
Identity = 124/212 (58.49%), Postives = 153/212 (72.17%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQT-------------------DVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQT                   DVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Human
Match: RAC2 (Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802])

HSP 1 Score: 236.884 bits (603), Expect = 7.379e-79
Identity = 112/181 (61.88%), Postives = 140/181 (77.35%), Query Frame = 3 
Query:  102 AVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            AVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  S+ NV+ KWF EV H+  +TPIILVGTKLDLRD+KD  E  K +   +P+TY QGLAL +EI +VKY+ECSA TQ  LK VF+EA+R VL     R++ + CS L
Sbjct:    6 AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKL-APITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL 185
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Celegans
Match: ced-10 (Ras-related protein ced-10 [Source:UniProtKB/Swiss-Prot;Acc:Q03206])

HSP 1 Score: 246.514 bits (628), Expect = 4.833e-83
Identity = 115/193 (59.59%), Postives = 150/193 (77.72%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DG+PINLGLWDTAGQ+D+D +R +SYPQTDVFL+CF+L N  SF NV+ KW+ EVSH+  NTPIILVGTK DLR+++D  E  + +    PV+  QG  + +EI AVKY+ECSA TQ  LK VF+EA+R VL   ++ K++K C+ L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLGLWDTAGQEDYDRLRPLSYPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADLREDRDTVERLRERRL-QPVSQTQGYVMAKEIKAVKYLECSALTQRGLKQVFDEAIRAVLTPPQRAKKSK-CTVL 191
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Celegans
Match: rac-2 (Ras-related protein rac-2 [Source:UniProtKB/Swiss-Prot;Acc:Q94124])

HSP 1 Score: 225.328 bits (573), Expect = 1.212e-74
Identity = 109/196 (55.61%), Postives = 142/196 (72.45%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNK---TKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    I TVFD  S N+M+DG+PINL LWDTAGQDD+D  R +S+PQTDVFL+CF+L N  SF NV+ KW+ EVSH+  NTPIILVGTK DLR+++D  E  + +    PV++ QG  + +EI AVKY+ECSA TQ  LK VF+EA+R  L      + R +   C+ L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLLSYTTNAFPGEYILTVFDTYSTNVMVDGRPINLSLWDTAGQDDYDQFRHLSFPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADLREDRDTIERLRERRL-QPVSHTQGYVMAKEIKAVKYLECSALTQIGLKQVFDEAIRTGLTPPQTPQTRAKKSNCTVL 195
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Celegans
Match: mig-2 (Rac-like GTPase [Source:UniProtKB/TrEMBL;Acc:G5EBV3])

HSP 1 Score: 220.705 bits (561), Expect = 9.119e-73
Identity = 104/192 (54.17%), Postives = 140/192 (72.92%), Query Frame = 3 
Query:   69 RSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            R IKCVV+GDG VGKTC+L+S+TTD F    +PTVFDN SA M +DG  +NLGLWDTAGQ+D+D +R +SYPQTDVF++CFS+V+ VSF NV  KW  E+  +  + P+ILVGTKLDLRD  +     + +   SP++  QG+ + Q+I AVKY+ECSA TQ+ L  VFE+AVR +L+  K +K+ K C+ +
Sbjct:    6 RQIKCVVVGDGTVGKTCMLISYTTDSFPVQYVPTVFDNYSAQMSLDGNVVNLGLWDTAGQEDYDRLRPLSYPQTDVFILCFSVVSPVSFDNVASKWIPEIRQHCPDAPVILVGTKLDLRDEAEPMRALQAE-GKSPISKTQGMKMAQKIKAVKYLECSALTQQGLTQVFEDAVRSILH-PKPQKKKKSCNIM 195
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Celegans
Match: cdc-42 (Cell division control protein 42 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q05062])

HSP 1 Score: 209.149 bits (531), Expect = 2.391e-68
Identity = 101/193 (52.33%), Postives = 139/193 (72.02%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    +PTVFDN +  +MI G+P  LGL+DTAGQ+D+D +R +SYPQTDVFL+CFS+V   SF NV+EKW  E+SH+   TP +LVGT++DLRD+    E    +    PV+   G  L +E+ AVKY+ECSA TQ+ LK VF+EA+   L+  ++ K+ K C+ L
Sbjct:    1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVAPASFENVREKWVPEISHHCSKTPFLLVGTQVDLRDDPGMLEK-LAKNKQKPVSTDVGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALDPPQQEKKKK-CNIL 191
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Celegans
Match: rho-1 (Ras-like GTP-binding protein rhoA [Source:UniProtKB/Swiss-Prot;Acc:Q22038])

HSP 1 Score: 177.178 bits (448), Expect = 1.051e-55
Identity = 83/176 (47.16%), Postives = 119/176 (67.61%), Query Frame = 3 
Query:   78 KCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNK 605
            K V++GDGA GKTC+L+ F+ D F    +PTVF+N  A++ +DGK + L LWDTAGQ+D+D +R +SYP TDV L+CFS+ +  S  N+ EKW  EV H+  N PIILVG K DLR +      +  ++   PV  +QG A+ ++IGA  Y+ECSAKT++ ++ VFE+A +  L +
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPDVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKRDLRSDPQ-TVRELAKMKQEPVKPEQGRAIAEQIGAFAYLECSAKTKDGIREVFEKATQAALQQ 181
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Fly
Match: Rac1 (gene:FBgn0010333 transcript:FBtr0072730)

HSP 1 Score: 256.914 bits (655), Expect = 5.082e-87
Identity = 121/193 (62.69%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KPINLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLVN  SF NV+ KW+ EV H+  +TPIILVGTKLDLRD+K+  E  + +   +P+TY QGLA+ +EIGAVKY+ECSA TQ+ LK VF+EA+R VL    + K  + C+ L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEKLRDKKL-APITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVLCPVLQPKSKRKCALL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Fly
Match: Rac1 (gene:FBgn0010333 transcript:FBtr0331868)

HSP 1 Score: 256.914 bits (655), Expect = 5.082e-87
Identity = 121/193 (62.69%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KPINLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLVN  SF NV+ KW+ EV H+  +TPIILVGTKLDLRD+K+  E  + +   +P+TY QGLA+ +EIGAVKY+ECSA TQ+ LK VF+EA+R VL    + K  + C+ L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEKLRDKKL-APITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVLCPVLQPKSKRKCALL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Fly
Match: Rac2 (gene:FBgn0014011 transcript:FBtr0076867)

HSP 1 Score: 252.292 bits (643), Expect = 3.770e-85
Identity = 120/193 (62.18%), Postives = 149/193 (77.20%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KPINLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLVN  SF NV+ KWF EV H+  + PIILVGTKLDLRD+K   E  K +   +P+TY QGLA+ +EI AVKY+ECSA TQ+ LK VF+EA+R VL    +  +   C+ L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLKDKKL-TPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPVVRGPKRHKCALL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Fly
Match: Rac2 (gene:FBgn0014011 transcript:FBtr0332800)

HSP 1 Score: 252.292 bits (643), Expect = 3.770e-85
Identity = 120/193 (62.18%), Postives = 149/193 (77.20%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KPINLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLVN  SF NV+ KWF EV H+  + PIILVGTKLDLRD+K   E  K +   +P+TY QGLA+ +EI AVKY+ECSA TQ+ LK VF+EA+R VL    +  +   C+ L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLKDKKL-TPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPVVRGPKRHKCALL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Fly
Match: Cdc42 (gene:FBgn0010341 transcript:FBtr0309215)

HSP 1 Score: 216.853 bits (551), Expect = 3.154e-71
Identity = 104/194 (53.61%), Postives = 143/194 (73.71%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRD-NKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    +PTVFDN +  +MI G+P  LGL+DTAGQ+D+D +R +SYPQTDVFL+CFS+V+  SF NVKEKW  E++H+ + TP +LVGT++DLRD N   ++  K +    P+T +QG  L +E+ AVKY+ECSA TQ+ LK VF+EA+   L   +  K+ K C FL
Sbjct:    1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDENSTLEKLAKNK--QKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALEPPEPTKKRK-CKFL 191
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Zebrafish
Match: rac1b (Rac family small GTPase 1b [Source:ZFIN;Acc:ZDB-GENE-060312-45])

HSP 1 Score: 264.618 bits (675), Expect = 8.021e-90
Identity = 124/193 (64.25%), Postives = 154/193 (79.79%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+ + TPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR + CS L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCQTTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCSLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Zebrafish
Match: rac3b (Rac family small GTPase 3b [Source:ZFIN;Acc:ZDB-GENE-080220-21])

HSP 1 Score: 263.848 bits (673), Expect = 1.633e-89
Identity = 124/193 (64.25%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  + +   SP+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR K C+  
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKL-SPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRGKRCTLF 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Zebrafish
Match: rac3a (Rac family small GTPase 3a [Source:ZFIN;Acc:ZDB-GENE-040718-256])

HSP 1 Score: 262.307 bits (669), Expect = 5.617e-89
Identity = 123/191 (64.40%), Postives = 153/191 (80.10%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCS 638
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  + +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR K C+
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKL-APITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRGKKCT 190
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Zebrafish
Match: rac1a (Rac family small GTPase 1a [Source:ZFIN;Acc:ZDB-GENE-030131-5415])

HSP 1 Score: 258.07 bits (658), Expect = 3.038e-87
Identity = 123/193 (63.73%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     ++R + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKRRRRRCLLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Zebrafish
Match: rac2 (Rac family small GTPase 2 [Source:ZFIN;Acc:ZDB-GENE-040625-27])

HSP 1 Score: 251.906 bits (642), Expect = 8.277e-85
Identity = 120/193 (62.18%), Postives = 149/193 (77.20%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  +TPIILVGTKLDLRD K+  E  K +   +P+TY QGLAL +EI AVKY+ECSA TQ  LK VF+EA+R VL     + + K C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDEKETIEKLKEKKL-APITYPQGLALAKEIDAVKYLECSALTQRGLKTVFDEAIRAVLCPQPTKVKKKGCVML 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Xenopus
Match: rac1 (Rac family small GTPase 1 [Source:NCBI gene;Acc:448118])

HSP 1 Score: 263.077 bits (671), Expect = 4.435e-89
Identity = 124/193 (64.25%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Xenopus
Match: nab2 (NGFI-A binding protein 2 (EGR1 binding protein 2) [Source:Xenbase;Acc:XB-GENE-957953])

HSP 1 Score: 258.455 bits (659), Expect = 2.322e-87
Identity = 121/191 (63.35%), Postives = 152/191 (79.58%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCS 638
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  + +   SP+TY QGLA+ +EIG+VKY+ECSA TQ  LK VF+EA+R VL     ++  K C+
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKRL-SPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKRAGKKCT 190
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Xenopus
Match: yju2 (YJU2 splicing factor homolog [Source:Xenbase;Acc:XB-GENE-5938025])

HSP 1 Score: 250.751 bits (639), Expect = 2.706e-84
Identity = 119/193 (61.66%), Postives = 148/193 (76.68%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  S+ NV+ KW+ EV H+  +TPIILVGTKLDLRD+K+  E  K +   SP++Y QGLAL +EI AVKY+ECSA TQ  LK VF+EA+R VL     R     C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKETIEKLKEKKL-SPISYPQGLALAKEIEAVKYLECSALTQRGLKTVFDEAIRAVLCPPPSRPNKAKCVVL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Xenopus
Match: nab2 (NGFI-A binding protein 2 (EGR1 binding protein 2) [Source:Xenbase;Acc:XB-GENE-957953])

HSP 1 Score: 247.669 bits (631), Expect = 4.249e-83
Identity = 117/189 (61.90%), Postives = 148/189 (78.31%), Query Frame = 3 
Query:   72 SIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCS 638
            S++CV+I  GAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  + +   SP+TY QGLA+ +EIG+VKY+ECSA TQ  LK VF+EA+R VL     ++  K C+
Sbjct:    3 SLRCVIICWGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKRL-SPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKRAGKKCT 190
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Xenopus
Match: yju2 (YJU2 splicing factor homolog [Source:Xenbase;Acc:XB-GENE-5938025])

HSP 1 Score: 229.565 bits (584), Expect = 7.350e-76
Identity = 110/181 (60.77%), Postives = 136/181 (75.14%), Query Frame = 3 
Query:  102 AVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            AVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  S+ NV+ KW+ EV H+  +TPIILVGTKLDLRD+K+  E  K +   SP++Y QGLAL +EI AVKY+ECSA TQ  LK VF+EA+R VL     R     C  L
Sbjct:   12 AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKETIEKLKEKKL-SPISYPQGLALAKEIEAVKYLECSALTQRGLKTVFDEAIRAVLCPPPSRPNKAKCVVL 191
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Mouse
Match: Rac1 (Rac family small GTPase 1 [Source:MGI Symbol;Acc:MGI:97845])

HSP 1 Score: 263.077 bits (671), Expect = 3.359e-89
Identity = 124/193 (64.25%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Mouse
Match: Rac2 (Rac family small GTPase 2 [Source:MGI Symbol;Acc:MGI:97846])

HSP 1 Score: 255.758 bits (652), Expect = 2.295e-86
Identity = 120/193 (62.18%), Postives = 152/193 (78.76%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  S+ NV+ KWF EV H+  +TPIILVGTKLDLRD+KD  E  K +   +P+TY QGLAL ++I +VKY+ECSA TQ  LK VF+EA+R VL     R++ + CS L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKL-APITYPQGLALAKDIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRPCSLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Mouse
Match: Rac3 (Rac family small GTPase 3 [Source:MGI Symbol;Acc:MGI:2180784])

HSP 1 Score: 251.521 bits (641), Expect = 9.642e-85
Identity = 116/178 (65.17%), Postives = 147/178 (82.58%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVL 599
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  +TPI+LVGTKLDLRD+KD  E  + +   +P+TY QGLA+ +EIG+VKY+ECSA TQ  LK VF+EA+R VL
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKL-APITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVL 177
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Mouse
Match: Rac1 (Rac family small GTPase 1 [Source:MGI Symbol;Acc:MGI:97845])

HSP 1 Score: 251.136 bits (640), Expect = 2.557e-84
Identity = 124/212 (58.49%), Postives = 153/212 (72.17%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQT-------------------DVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQT                   DVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGDTCGKDRPSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Mouse
Match: Rac3 (Rac family small GTPase 3 [Source:MGI Symbol;Acc:MGI:2180784])

HSP 1 Score: 231.106 bits (588), Expect = 8.494e-77
Identity = 107/166 (64.46%), Postives = 135/166 (81.33%), Query Frame = 3 
Query:  102 AVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVL 599
            AVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  +TPI+LVGTKLDLRD+KD  E  + +   +P+TY QGLA+ +EIG+VKY+ECSA TQ  LK VF+EA+R VL
Sbjct:    6 AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKL-APITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVL 170
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. UniProt/SwissProt
Match: sp|Q6RUV5|RAC1_RAT (Ras-related C3 botulinum toxin substrate 1 OS=Rattus norvegicus OX=10116 GN=Rac1 PE=1 SV=1)

HSP 1 Score: 263.077 bits (671), Expect = 2.350e-88
Identity = 124/193 (64.25%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. UniProt/SwissProt
Match: sp|P63001|RAC1_MOUSE (Ras-related C3 botulinum toxin substrate 1 OS=Mus musculus OX=10090 GN=Rac1 PE=1 SV=1)

HSP 1 Score: 263.077 bits (671), Expect = 2.350e-88
Identity = 124/193 (64.25%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. UniProt/SwissProt
Match: sp|P63000|RAC1_HUMAN (Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1)

HSP 1 Score: 263.077 bits (671), Expect = 2.350e-88
Identity = 124/193 (64.25%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. UniProt/SwissProt
Match: sp|P62999|RAC1_CANLF (Ras-related C3 botulinum toxin substrate 1 OS=Canis lupus familiaris OX=9615 GN=RAC1 PE=2 SV=1)

HSP 1 Score: 263.077 bits (671), Expect = 2.350e-88
Identity = 124/193 (64.25%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. UniProt/SwissProt
Match: sp|P62998|RAC1_BOVIN (Ras-related C3 botulinum toxin substrate 1 OS=Bos taurus OX=9913 GN=RAC1 PE=1 SV=1)

HSP 1 Score: 263.077 bits (671), Expect = 2.350e-88
Identity = 124/193 (64.25%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. TrEMBL
Match: A0A131XE62 (Putative ras-related c3 botulinum toxin substrate 1 OS=Hyalomma excavatum OX=257692 PE=2 SV=1)

HSP 1 Score: 267.314 bits (682), Expect = 1.273e-87
Identity = 126/193 (65.28%), Postives = 156/193 (80.83%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKPINLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLVN  SF NV+ KW+ EVSH+  NTPIILVGTKLDLR++KD  E  + +   +P+TY QGLA+ +EIGAVKY+ECSA TQ+ LK VF+EA+R VL    K K+ + CS L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVSHHCPNTPIILVGTKLDLREDKDTVEKLRDRKL-APITYPQGLAMAKEIGAVKYLECSALTQKGLKNVFDEAIRAVLCPQPKPKKRRPCSLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. TrEMBL
Match: A0A1E1X0F3 (Putative ras-related c3 botulinum toxin substrate 1 OS=Amblyomma aureolatum OX=187763 PE=2 SV=1)

HSP 1 Score: 267.314 bits (682), Expect = 1.273e-87
Identity = 126/193 (65.28%), Postives = 156/193 (80.83%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKPINLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLVN  SF NV+ KW+ EVSH+  NTPIILVGTKLDLR++KD  E  + +   +P+TY QGLA+ +EIGAVKY+ECSA TQ+ LK VF+EA+R VL    K K+ + CS L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVSHHCPNTPIILVGTKLDLREDKDTVEKLRDRKL-APITYPQGLAMAKEIGAVKYLECSALTQKGLKNVFDEAIRAVLCPQPKPKKRRPCSLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. TrEMBL
Match: A0A023GI74 (Putative ras-related c3 botulinum toxin substrate 1 OS=Amblyomma triste OX=251400 PE=2 SV=1)

HSP 1 Score: 267.314 bits (682), Expect = 1.273e-87
Identity = 126/193 (65.28%), Postives = 156/193 (80.83%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKPINLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLVN  SF NV+ KW+ EVSH+  NTPIILVGTKLDLR++KD  E  + +   +P+TY QGLA+ +EIGAVKY+ECSA TQ+ LK VF+EA+R VL    K K+ + CS L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVSHHCPNTPIILVGTKLDLREDKDTVEKLRDRKL-APITYPQGLAMAKEIGAVKYLECSALTQKGLKNVFDEAIRAVLCPQPKPKKRRPCSLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. TrEMBL
Match: A0A224Z5J4 (Ras-related protein Rac1 OS=Rhipicephalus zambeziensis OX=60191 PE=4 SV=1)

HSP 1 Score: 267.314 bits (682), Expect = 1.273e-87
Identity = 126/193 (65.28%), Postives = 156/193 (80.83%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKPINLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLVN  SF NV+ KW+ EVSH+  NTPIILVGTKLDLR++KD  E  + +   +P+TY QGLA+ +EIGAVKY+ECSA TQ+ LK VF+EA+R VL    K K+ + CS L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVSHHCPNTPIILVGTKLDLREDKDTVEKLRDRKL-APITYPQGLAMAKEIGAVKYLECSALTQKGLKNVFDEAIRAVLCPQPKPKKRRPCSLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. TrEMBL
Match: A0A1E1XJ72 (Putative ras-related c3 botulinum toxin substrate 1 OS=Amblyomma sculptum OX=1581419 PE=2 SV=1)

HSP 1 Score: 267.314 bits (682), Expect = 1.273e-87
Identity = 126/193 (65.28%), Postives = 156/193 (80.83%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKPINLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLVN  SF NV+ KW+ EVSH+  NTPIILVGTKLDLR++KD  E  + +   +P+TY QGLA+ +EIGAVKY+ECSA TQ+ LK VF+EA+R VL    K K+ + CS L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVSHHCPNTPIILVGTKLDLREDKDTVEKLRDRKL-APITYPQGLAMAKEIGAVKYLECSALTQKGLKNVFDEAIRAVLCPQPKPKKRRPCSLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Cavefish
Match: rac3b (ras-related C3 botulinum toxin substrate 3-like [Source:NCBI gene;Acc:111192386])

HSP 1 Score: 263.848 bits (673), Expect = 1.384e-89
Identity = 124/193 (64.25%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  + +   SP+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR K C+  
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKL-SPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRGKRCTLF 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Cavefish
Match: rac1a (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:103034053])

HSP 1 Score: 263.077 bits (671), Expect = 2.638e-89
Identity = 124/193 (64.25%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKL-TPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Cavefish
Match: rac3a (Rac family small GTPase 3 [Source:NCBI gene;Acc:103047109])

HSP 1 Score: 262.307 bits (669), Expect = 4.761e-89
Identity = 123/191 (64.40%), Postives = 153/191 (80.10%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCS 638
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  + +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR K C+
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKL-APITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRGKKCT 190
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Cavefish
Match: rac1b (ras-related C3 botulinum toxin substrate 1-like [Source:NCBI gene;Acc:111192975])

HSP 1 Score: 262.307 bits (669), Expect = 5.253e-89
Identity = 122/193 (63.21%), Postives = 154/193 (79.79%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD++D  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ +LK VF+EA+R VL     + R + C+ L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDQDTIEKLKERKL-TPITYPQGLAMAKEIGAVKYLECSALTQRDLKTVFDEAIRAVLCPPPVKSRKRKCTLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Cavefish
Match: rac1b (ras-related C3 botulinum toxin substrate 1-like [Source:NCBI gene;Acc:111192975])

HSP 1 Score: 262.307 bits (669), Expect = 5.253e-89
Identity = 122/193 (63.21%), Postives = 154/193 (79.79%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD++D  E  K +   +P+TY QGLA+ +EIGAVKY+ECSA TQ +LK VF+EA+R VL     + R + C+ L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDQDTIEKLKERKL-TPITYPQGLAMAKEIGAVKYLECSALTQRDLKTVFDEAIRAVLCPPPVKSRKRKCTLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009835.1 (pep scaffold:Pmarinus_7.0:GL479385:19931:31465:1 gene:ENSPMAG00000008880.1 transcript:ENSPMAT00000009835.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 256.529 bits (654), Expect = 2.093e-87
Identity = 124/193 (64.25%), Postives = 153/193 (79.27%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  + +   +P+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR K C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTVEKLREKKL-APITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPAKKRKKKCQLL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007368.1 (pep scaffold:Pmarinus_7.0:GL476419:214196:224439:-1 gene:ENSPMAG00000006646.1 transcript:ENSPMAT00000007368.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 234.572 bits (597), Expect = 7.768e-79
Identity = 112/194 (57.73%), Postives = 148/194 (76.29%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKK-RKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+SF+ + F    IPTVFDN + N+M+DGK +NLGLWDTAGQ+D+D +R +SYPQTD+FLICFS+V+  S+ NV+ KWFKEV H+   TPIILVGTK D R++KD  +H + +    PVT  QGL+L +EIGA+KY+ECSA TQ  LK VF+E VR V++   K  ++ K C+ L
Sbjct:    1 MQAIKCVVVGDGAVGKTCMLISFSNNTFPGEYIPTVFDNYAVNLMVDGKYVNLGLWDTAGQEDYDRLRPLSYPQTDIFLICFSVVSPSSYDNVRVKWFKEVRHHCPETPIILVGTKQDQREDKDILKHLEEKSM-QPVTNAQGLSLAKEIGAIKYLECSALTQRGLKNVFDETVRAVISPEPKIERKKKSCALL 193
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Sea Lamprey
Match: rhoj (ras homolog family member J [Source:ZFIN;Acc:ZDB-GENE-040724-272])

HSP 1 Score: 186.422 bits (472), Expect = 1.307e-59
Identity = 87/185 (47.03%), Postives = 129/185 (69.73%), Query Frame = 3 
Query:   75 IKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTK 629
            +KCVV+GDGAVGKTC+++S+  D F    +PTVFD+ + N+ + G    LGL+DTAGQ+D+  +R +SYP TD+F+ICFS+VN  S+ NVKE+W  E+     + P +LVGT++DLRD        K ++   P+T+QQG+ L ++IGA  Y+ECSA TQ+ LK VF+EA+  +L + K ++ T+
Sbjct:   21 LKCVVVGDGAVGKTCLIMSYANDAFPEQYVPTVFDHYAVNVKVGGSCYLLGLYDTAGQEDYHQLRPLSYPNTDMFMICFSVVNPASYHNVKEEWVPELRACCPDVPYLLVGTQIDLRDATKTLMRLK-ELKEKPMTHQQGVKLAKQIGAHCYLECSALTQKGLKAVFDEAILTILQRKKCKRSTR 204
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004439.1 (pep scaffold:Pmarinus_7.0:GL476335:1598569:1600956:1 gene:ENSPMAG00000004041.1 transcript:ENSPMAT00000004439.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 182.57 bits (462), Expect = 2.312e-58
Identity = 89/189 (47.09%), Postives = 124/189 (65.61%), Query Frame = 3 
Query:   78 KCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            K V++GDGA GKTC+L+ F+ D F    +PTVF+N  A++ +DGK + L LWDTAGQ+D+D +R +SYP TDV L+CFS+ +  S  N+ EKW  EV H+  N PIILVG K DLR N D  + +  ++   PV  ++G  +   I A  Y+ECSAKT++ ++ VFE A R  L + +KRK+T  C  L
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR-NDDNTKRELAKMKQEPVRVEEGRDMANRINAFGYMECSAKTKDGVREVFEMATRAAL-QVRKRKKTGGCRLL 193
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001838.1 (pep scaffold:Pmarinus_7.0:GL478831:173097:182385:-1 gene:ENSPMAG00000001664.1 transcript:ENSPMAT00000001838.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 174.866 bits (442), Expect = 3.281e-55
Identity = 88/196 (44.90%), Postives = 122/196 (62.24%), Query Frame = 3 
Query:   78 KCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL*LFLISI 665
            K V++GDGA GKTC+L+ F+ D F    +PTVF+N  A++ +DGK + L LWDTAGQ+D+D +R +SYP TDV L+CFS+ +  S  N+ EKW  EV H+  N PIILVG K DLR N +    +  ++   PV  ++G  +   I A  Y+ECSAKT++ ++ VFE A R  L  T K           L+LIS+
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR-NDESTRRELAKMKQEPVKSEEGRDMANRINAFGYMECSAKTKDGVREVFEMATRAALQLTAK-----------LYLISV 190
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Yeast
Match: CDC42 (Small rho-like GTPase; essential for establishment and maintenance of cell polarity; plays a role late in cell fusion via activation of key cell fusion regulator Fus2p; mutants have defects in the organization of actin and septins; human homolog CDC42 can complement yeast cdc42 mutant [Source:SGD;Acc:S000004219])

HSP 1 Score: 206.068 bits (523), Expect = 9.266e-68
Identity = 100/193 (51.81%), Postives = 139/193 (72.02%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M+++KCVV+GDGAVGKTC+L+S+TT+ F    +PTVFDN +  +MI  +P  LGL+DTAGQ+D+D +R +SYP TDVFL+CFS+++  SF NVKEKWF EV H+    P ++VGT++DLRD+K   E  + Q    P+T +QG  L +E+ AVKY+ECSA TQ  LK VF+EA+   L +    K++K C+ L
Sbjct:    1 MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCLVVGTQIDLRDDKVIIEKLQRQRL-RPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAAL-EPPVIKKSKKCAIL 191
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Yeast
Match: RHO1 (GTP-binding protein of the rho subfamily of Ras-like proteins; involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p) [Source:SGD;Acc:S000006369])

HSP 1 Score: 168.703 bits (426), Expect = 6.104e-53
Identity = 84/179 (46.93%), Postives = 116/179 (64.80%), Query Frame = 3 
Query:   78 KCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKK 614
            K V++GDGA GKTC+L+ F+   F    +PTVF+N  A++ +DG+ + L LWDTAGQ+D+D +R +SYP ++V LICFS+    S  NV+EKW  EV H+ +  PIILVG K+DLR++    E  + Q    PVT Q+G ++  +IGA  Y ECSAKT   ++ VFE A R  L    K
Sbjct:   12 KLVIVGDGACGKTCLLIVFSKGQFPEVYVPTVFENYVADVEVDGRRVELALWDTAGQEDYDRLRPLSYPDSNVVLICFSIDLPDSLENVQEKWIAEVLHFCQGVPIILVGCKVDLRNDPQTIEQLR-QEGQQPVTSQEGQSVADQIGATGYYECSAKTGYGVREVFEAATRASLMGKSK 189
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Yeast
Match: RHO5 (Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; RAC1 ortholog; regulated by phosphorylation and ubiquitination; likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity [Source:SGD;Acc:S000005124])

HSP 1 Score: 159.844 bits (403), Expect = 5.062e-48
Identity = 95/220 (43.18%), Postives = 119/220 (54.09%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMI------------------------------DGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYS--ENT---------PIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGL-ALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVL 599
            MRSIKCV+IGDGAVGKT +L+S+TT+ F    +PTVFDN S  + I                              D K   + LWDTAGQ+D+D +R + YPQTD+FLICFS+    SF NV EKW  E+   S  E T         PI+LVGTK DLRD  D     K Q  +S    Q+ +  L Q  G + Y ECSA TQ  ++ VFE+AVR  +
Sbjct:    1 MRSIKCVIIGDGAVGKTSLLISYTTNSFPTDYVPTVFDNYSTTIAIPNGTASSPLELDNGNDKRGSLSSASSSPSTDRKLYKINLWDTAGQEDYDRLRPLCYPQTDIFLICFSVSEHASFANVTEKWLPELKQTSNIEGTSLYTKLGKYPILLVGTKSDLRD--DPATQKKLQEANSDYVSQEEIDELVQRCGFMGYTECSAATQAGVREVFEQAVRYAI 218
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Yeast
Match: RHO3 (Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p [Source:SGD;Acc:S000001380])

HSP 1 Score: 142.895 bits (359), Expect = 1.251e-42
Identity = 73/194 (37.63%), Postives = 113/194 (58.25%), Query Frame = 3 
Query:   78 KCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDE--------------HDKGQVFSSP------VTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVL 599
            K V++GDGA GKT +L  FT   F     PTVF+N   ++ +D K I L LWDTAGQ++FD +R +SY  T   ++CFS+ ++ S  NV+ KW  E++ + E   ++LV  K DLR+N++                 +D G   +S       ++Y++GLA+ ++IGA++Y+ECSAK  + +   F EA R+ L
Sbjct:   18 KIVILGDGACGKTSLLNVFTRGYFPEVYEPTVFENYIHDIFVDSKHITLSLWDTAGQEEFDRLRSLSYSDTQCIMLCFSIDSRDSLENVQNKWVGEITDHCEGVKLVLVALKCDLRNNENESNAITPNNIQQDNSVSNDNGNNINSTSNGKNLISYEEGLAMAKKIGALRYLECSAKLNKGVNEAFTEAARVAL 211
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Yeast
Match: RHO4 (Non-essential small GTPase; member of the Rho/Rac subfamily of Ras-like proteins; likely to be involved in the establishment of cell polarity; has long N-terminal extension that plays an important role in Rho4p function and is shared with Rho4 homologs in other yeasts and filamentous fungi [Source:SGD;Acc:S000001763])

HSP 1 Score: 144.436 bits (363), Expect = 1.558e-42
Identity = 72/177 (40.68%), Postives = 110/177 (62.15%), Query Frame = 3 
Query:   75 IKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMM-IDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLN 602
            +K VV+GDGAVGKTC+L+S+    F    IPT+F+N   N+   +G+ I L LWDTAGQ+++  +R +SY   DV ++C+S+ +K S  NV++ WF EV H+  +TPI+LVG K DL +  +          S  V      +L + +GA  +I+CSA+ +EN+  VFE A+  +L+
Sbjct:   73 LKIVVVGDGAVGKTCLLISYVQGTFPTDYIPTIFENYVTNIEGPNGQIIELALWDTAGQEEYSRLRPLSYTNADVLMVCYSVGSKTSLKNVEDLWFPEVKHFCPSTPIMLVGLKSDLYEADN---------LSDLVEPSSAESLAKRLGAFAHIQCSARLKENIDEVFETAIHTLLS 240
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Nematostella
Match: EDO38536 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCK6])

HSP 1 Score: 256.914 bits (655), Expect = 2.359e-87
Identity = 122/195 (62.56%), Postives = 154/195 (78.97%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTK--KRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKPINLGLWDTAGQ+D+D +R +SYPQTDVFLICFSL++  S+ NV+ KW+ EVSH+  NTPI+LVGTKLDLRD+K+  +  K +    P+ Y QGL + +EIGAVKY+ECSA TQ+ LK VF+EA+R VL  TK  K+ R K C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASYENVRAKWYPEVSHHCPNTPIVLVGTKLDLRDDKETIDKLKEKKL-GPIGYTQGLQMAKEIGAVKYLECSALTQKGLKTVFDEAIRAVLCPTKPAKKPRNKGCKLL 194
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Nematostella
Match: EDO35019 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMN7])

HSP 1 Score: 235.343 bits (599), Expect = 7.025e-79
Identity = 112/193 (58.03%), Postives = 150/193 (77.72%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DG+PINLGLWDTAGQ+D+D +R +SYPQTDVFLICFS+++  SF NV+ KW+ EVSH+   TPIILVGTK DLR++K+  E  K +   +P++   GL + +EI A KY+ECSA TQ+ LK VF++A+R VL   K +K+ + C+ L
Sbjct:    1 MQAIKCVVVGDGAVGKTCMLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSVISPASFENVRAKWYPEVSHHCPGTPIILVGTKTDLREDKEMIEKLKEKKL-NPLSTSHGLQMAKEIKAAKYLECSALTQKGLKTVFDDAIRAVLEPKKPQKKRRKCNPL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Nematostella
Match: EDO37472 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFJ1])

HSP 1 Score: 206.838 bits (525), Expect = 9.999e-68
Identity = 99/194 (51.03%), Postives = 140/194 (72.16%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKD-FDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    +PTVFDN +  +MI G+P  LGL+DTAGQ+D+D +R +SYPQTDVFL+CFS+V+  SF NVKEKW  E++H+   TP +LVGT++DLRD++   ++  K +    P+  +    L +E+ AVKY+ECSA TQ+ LK VF+EA+   L   + +K+ K C  L
Sbjct:    1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQVDLRDDQGTIEKLSKNK--QKPIAVEAAEKLARELRAVKYVECSALTQKGLKNVFDEAILAALEPPEPQKKKK-CRLL 191
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Nematostella
Match: EDO39465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9Y5])

HSP 1 Score: 174.481 bits (441), Expect = 7.186e-55
Identity = 85/178 (47.75%), Postives = 117/178 (65.73%), Query Frame = 3 
Query:   78 KCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVF---SSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLN 602
            K V++GDGA GKTC+L+ F+ D F    +PTVF+N  A++ +DGK + L LWDTAGQ+D+D +R +SYP TDV L+CFS+ +  S  N+ EKW  EV H+  N PIILVG K DLR     DE+ K ++      PV  ++G A+  +I A  Y+ECSAKT++ ++ VFE A R  L 
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR----MDENTKRELQKMKQEPVKIEEGRAMADKISAYAYLECSAKTKDGVREVFETATRAALQ 180
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Nematostella
Match: EDO36553 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI94])

HSP 1 Score: 157.147 bits (396), Expect = 1.519e-44
Identity = 74/161 (45.96%), Postives = 109/161 (67.70%), Query Frame = 3 
Query:  111 KTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRI 593
            K+  L++ TT+ F    IPTVFDN S+N+M+DGK  N+GLWDTAGQ+D+D +R +SYP TDVFL+CF + ++ SF N++ KW  E++H+   TP ILVG K DLR  +     D       P+TY++G AL + +G ++Y+E S+ TQ+ +K V   A+R+
Sbjct:   18 KSAFLITATTNAFPGEYIPTVFDNYSSNIMLDGKAYNVGLWDTAGQEDYDRLRPLSYPMTDVFLVCFDIGSRTSFENIESKWLPELNHHMPETPKILVGNKRDLRSAQQNTSRD-------PITYEEGKALAKRLG-MQYLENSSLTQDGVKDVMSAAIRV 170
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Medaka
Match: ENSORLT00000038381.1 (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:101175028])

HSP 1 Score: 256.914 bits (655), Expect = 6.340e-87
Identity = 122/193 (63.21%), Postives = 150/193 (77.72%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+   TPIILVGTKLDLRD+KD  E  K +   SP+ Y QGLA+ +EI AVKY+ECSA TQ  LK VF+EA+R VL     RK+ + C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPVTPIILVGTKLDLRDDKDTIEKLKEKKL-SPIIYPQGLAMAKEISAVKYLECSALTQRGLKTVFDEAIRAVLCPPPDRKKKRKCRIL 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Medaka
Match: RAC1 (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:101159016])

HSP 1 Score: 256.144 bits (653), Expect = 1.235e-86
Identity = 119/178 (66.85%), Postives = 147/178 (82.58%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVL 599
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+K+  E  K +   SP+TY QGLA+ +EIG+VKY+ECSA TQ  LK VF+EA+R VL
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKETTEKLKEKKL-SPITYPQGLAMAKEIGSVKYLECSALTQRGLKTVFDEAIRAVL 177
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Medaka
Match: RAC1 (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:101159016])

HSP 1 Score: 256.144 bits (653), Expect = 1.235e-86
Identity = 119/178 (66.85%), Postives = 147/178 (82.58%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVL 599
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+K+  E  K +   SP+TY QGLA+ +EIG+VKY+ECSA TQ  LK VF+EA+R VL
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKETTEKLKEKKL-SPITYPQGLAMAKEIGSVKYLECSALTQRGLKTVFDEAIRAVL 177
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Medaka
Match: ENSORLT00000041989.1 (Rac family small GTPase 2 [Source:NCBI gene;Acc:101163549])

HSP 1 Score: 250.751 bits (639), Expect = 1.531e-84
Identity = 119/193 (61.66%), Postives = 148/193 (76.68%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  S+ NV+ KW+ EV H+  +TPIILVGTKLDLRD KD  E  K +   +P+TY QGLAL +EI AVKY+ECSA TQ  LK VF+EA+R VL     + +   C  L
Sbjct:    1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWYPEVRHHCPSTPIILVGTKLDLRDEKDTIEKLKEKKL-APITYPQGLALAKEIDAVKYLECSALTQRGLKTVFDEAIRAVLCPQPAKVKKANCLML 192
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Medaka
Match: rac3b (ras-related C3 botulinum toxin substrate 3 [Source:NCBI gene;Acc:105354522])

HSP 1 Score: 243.047 bits (619), Expect = 2.321e-81
Identity = 115/180 (63.89%), Postives = 141/180 (78.33%), Query Frame = 3 
Query:  102 AVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSF 641
            AVGKTC+L+S+TT+ F    IPTVFDN SAN+M+DGKP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSLV+  SF NV+ KW+ EV H+  NTPIILVGTKLDLRD+KD  E  + +   SP+TY QGLA+ +EIGAVKY+ECSA TQ  LK VF+EA+R VL     +KR K C+ 
Sbjct:   18 AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKL-SPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRGKRCTM 196
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Planmine SMEST
Match: SMESG000005012.1 (SMESG000005012.1)

HSP 1 Score: 395.586 bits (1015), Expect = 8.897e-142
Identity = 192/193 (99.48%), Postives = 192/193 (99.48%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            MRSIKCVVIGDGAVGKTCILVSFTTDVFS SPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL
Sbjct:    1 MRSIKCVVIGDGAVGKTCILVSFTTDVFSSSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 193
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Planmine SMEST
Match: SMESG000005010.1 (SMESG000005010.1)

HSP 1 Score: 309.686 bits (792), Expect = 8.227e-108
Identity = 144/194 (74.23%), Postives = 170/194 (87.63%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTK-KRKRTKFCSFL 644
            MRSIKCVV+GDGAVGKTCIL+S+TTD F  + +PTVFDNMSAN+MI+G PINLGLWDTAGQ+++D +R +SYP+TDVFLICFSLVNK SF NVKEKW+KEVSH+S+ TPIILVGTKLDLR+ +  +E+DK Q+ SSPVTYQQGLALCQEIGAVKYIECSA+TQ NL+ VFEEA+R+V+NK K    R KFCS L
Sbjct:    1 MRSIKCVVVGDGAVGKTCILISYTTDAFPTTHVPTVFDNMSANVMIEGTPINLGLWDTAGQEEYDRLRPLSYPETDVFLICFSLVNKDSFANVKEKWYKEVSHFSKETPIILVGTKLDLREERALNENDKNQIRSSPVTYQQGLALCQEIGAVKYIECSARTQVNLRQVFEEAIRVVINKPKPSNPRFKFCSLL 194
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Planmine SMEST
Match: SMESG000024961.1 (SMESG000024961.1)

HSP 1 Score: 254.218 bits (648), Expect = 4.957e-86
Identity = 120/193 (62.18%), Postives = 152/193 (78.76%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M+ IKCVV+GDGAVGKTC+L+S+TT+ F    IPTVFDN SAN+M+D KP+NLGLWDTAGQ+D+D +R +SYPQTDVFLICFSL+N  S+ NV+ KW+ E++H+  NTPIILVGTKLDLR+N    E  K +  ++P++Y QGL L +EIGAVKY+ECSA TQ+ LK VF+EA+R VL     RK+T  C FL
Sbjct:    1 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDR-RNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKT--CKFL 190
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Planmine SMEST
Match: SMESG000024968.1 (SMESG000024968.1)

HSP 1 Score: 236.884 bits (603), Expect = 2.987e-79
Identity = 114/193 (59.07%), Postives = 146/193 (75.65%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M+ IKCVV+GDGAVGKTC+L+S+TT  F    IPTVFDN SAN+M+D KP+NLGLWDTAGQ+D+D +R +SYPQTDVF+ICFSLVN  S+ NV+ KW+ EV+++  NTPIILVGTKLDLRD    ++          ++Y QGL L +EIGA KY+ECSA TQ  LK VF+E++R+VL   K+++  K CS L
Sbjct:    1 MQGIKCVVVGDGAVGKTCLLISYTTSAFPGEYIPTVFDNYSANIMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFIICFSLVNPSSYENVRAKWYPEVNNHCPNTPIILVGTKLDLRDESQTNKT------GGHISYPQGLILMKEIGAKKYLECSALTQTGLKTVFDESIRVVLCP-KQKQNKKRCSIL 186
[Close]
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Planmine SMEST
Match: SMESG000005013.1 (SMESG000005013.1)

HSP 1 Score: 214.542 bits (545), Expect = 2.518e-70
Identity = 103/193 (53.37%), Postives = 140/193 (72.54%), Query Frame = 3 
Query:   66 MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKPINLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKEVSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEIGAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL 644
            M++IKCVV+GDG VGKTC L+S+TT+ F    +PT+FDN  AN+M+DG  INL LWDTAGQ+ +D +RV  Y  T VFL+CFS++++ ++ NVK  W KE+ +Y    PIILVGTK+DLR +    ++       S VTYQ+GL L ++I AVK++ECSAK++E L  VFEEA+R V+N+T KRK+ K CS L
Sbjct:    1 MKAIKCVVVGDGQVGKTCTLISYTTNRFPNEYVPTMFDNWCANLMVDGIGINLSLWDTAGQETYDQLRVTCYQNTSVFLVCFSVMDRTTYENVKYTWAKEIRNYCPKIPIILVGTKVDLR-HLAIGDNTSNSTNVSYVTYQEGLILAKQINAVKFVECSAKSREGLSQVFEEAIRAVINQTPKRKKPK-CSLL 191
The following BLAST results are available for this feature:
BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RAC14.893e-8964.25Rac family small GTPase 1 [Source:HGNC Symbol;Acc:... [more]
RAC25.566e-8762.69Rac family small GTPase 2 [Source:HGNC Symbol;Acc:... [more]
RAC31.404e-8465.17Rac family small GTPase 3 [Source:HGNC Symbol;Acc:... [more]
RAC13.231e-8458.49Rac family small GTPase 1 [Source:HGNC Symbol;Acc:... [more]
RAC27.379e-7961.88Rac family small GTPase 2 [Source:HGNC Symbol;Acc:... [more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ced-104.833e-8359.59Ras-related protein ced-10 [Source:UniProtKB/Swis... [more]
rac-21.212e-7455.61Ras-related protein rac-2 [Source:UniProtKB/Swiss... [more]
mig-29.119e-7354.17Rac-like GTPase [Source:UniProtKB/TrEMBL;Acc:G5EB... [more]
cdc-422.391e-6852.33Cell division control protein 42 homolog [Source:... [more]
rho-11.051e-5547.16Ras-like GTP-binding protein rhoA [Source:UniProt... [more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rac15.082e-8762.69gene:FBgn0010333 transcript:FBtr0072730[more]
Rac15.082e-8762.69gene:FBgn0010333 transcript:FBtr0331868[more]
Rac23.770e-8562.18gene:FBgn0014011 transcript:FBtr0076867[more]
Rac23.770e-8562.18gene:FBgn0014011 transcript:FBtr0332800[more]
Cdc423.154e-7153.61gene:FBgn0010341 transcript:FBtr0309215[more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rac1b8.021e-9064.25Rac family small GTPase 1b [Source:ZFIN;Acc:ZDB-GE... [more]
rac3b1.633e-8964.25Rac family small GTPase 3b [Source:ZFIN;Acc:ZDB-GE... [more]
rac3a5.617e-8964.40Rac family small GTPase 3a [Source:ZFIN;Acc:ZDB-GE... [more]
rac1a3.038e-8763.73Rac family small GTPase 1a [Source:ZFIN;Acc:ZDB-GE... [more]
rac28.277e-8562.18Rac family small GTPase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rac14.435e-8964.25Rac family small GTPase 1 [Source:NCBI gene;Acc:44... [more]
nab22.322e-8763.35NGFI-A binding protein 2 (EGR1 binding protein 2) ... [more]
yju22.706e-8461.66YJU2 splicing factor homolog [Source:Xenbase;Acc:X... [more]
nab24.249e-8361.90NGFI-A binding protein 2 (EGR1 binding protein 2) ... [more]
yju27.350e-7660.77YJU2 splicing factor homolog [Source:Xenbase;Acc:X... [more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rac13.359e-8964.25Rac family small GTPase 1 [Source:MGI Symbol;Acc:M... [more]
Rac22.295e-8662.18Rac family small GTPase 2 [Source:MGI Symbol;Acc:M... [more]
Rac39.642e-8565.17Rac family small GTPase 3 [Source:MGI Symbol;Acc:M... [more]
Rac12.557e-8458.49Rac family small GTPase 1 [Source:MGI Symbol;Acc:M... [more]
Rac38.494e-7764.46Rac family small GTPase 3 [Source:MGI Symbol;Acc:M... [more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6RUV5|RAC1_RAT2.350e-8864.25Ras-related C3 botulinum toxin substrate 1 OS=Ratt... [more]
sp|P63001|RAC1_MOUSE2.350e-8864.25Ras-related C3 botulinum toxin substrate 1 OS=Mus ... [more]
sp|P63000|RAC1_HUMAN2.350e-8864.25Ras-related C3 botulinum toxin substrate 1 OS=Homo... [more]
sp|P62999|RAC1_CANLF2.350e-8864.25Ras-related C3 botulinum toxin substrate 1 OS=Cani... [more]
sp|P62998|RAC1_BOVIN2.350e-8864.25Ras-related C3 botulinum toxin substrate 1 OS=Bos ... [more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A131XE621.273e-8765.28Putative ras-related c3 botulinum toxin substrate ... [more]
A0A1E1X0F31.273e-8765.28Putative ras-related c3 botulinum toxin substrate ... [more]
A0A023GI741.273e-8765.28Putative ras-related c3 botulinum toxin substrate ... [more]
A0A224Z5J41.273e-8765.28Ras-related protein Rac1 OS=Rhipicephalus zambezie... [more]
A0A1E1XJ721.273e-8765.28Putative ras-related c3 botulinum toxin substrate ... [more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rac3b1.384e-8964.25ras-related C3 botulinum toxin substrate 3-like [S... [more]
rac1a2.638e-8964.25ras-related C3 botulinum toxin substrate 1 [Source... [more]
rac3a4.761e-8964.40Rac family small GTPase 3 [Source:NCBI gene;Acc:10... [more]
rac1b5.253e-8963.21ras-related C3 botulinum toxin substrate 1-like [S... [more]
rac1b5.253e-8963.21ras-related C3 botulinum toxin substrate 1-like [S... [more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000009835.12.093e-8764.25pep scaffold:Pmarinus_7.0:GL479385:19931:31465:1 g... [more]
ENSPMAT00000007368.17.768e-7957.73pep scaffold:Pmarinus_7.0:GL476419:214196:224439:-... [more]
rhoj1.307e-5947.03ras homolog family member J [Source:ZFIN;Acc:ZDB-G... [more]
ENSPMAT00000004439.12.312e-5847.09pep scaffold:Pmarinus_7.0:GL476335:1598569:1600956... [more]
ENSPMAT00000001838.13.281e-5544.90pep scaffold:Pmarinus_7.0:GL478831:173097:182385:-... [more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
CDC429.266e-6851.81Small rho-like GTPase; essential for establishment... [more]
RHO16.104e-5346.93GTP-binding protein of the rho subfamily of Ras-li... [more]
RHO55.062e-4843.18Non-essential small GTPase of the Rho/Rac family o... [more]
RHO31.251e-4237.63Non-essential small GTPase of the Rho/Rac family o... [more]
RHO41.558e-4240.68Non-essential small GTPase; member of the Rho/Rac ... [more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO385362.359e-8762.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO350197.025e-7958.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO374729.999e-6851.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO394657.186e-5547.75Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO365531.519e-4445.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000038381.16.340e-8763.21ras-related C3 botulinum toxin substrate 1 [Source... [more]
RAC11.235e-8666.85ras-related C3 botulinum toxin substrate 1 [Source... [more]
RAC11.235e-8666.85ras-related C3 botulinum toxin substrate 1 [Source... [more]
ENSORLT00000041989.11.531e-8461.66Rac family small GTPase 2 [Source:NCBI gene;Acc:10... [more]
rac3b2.321e-8163.89ras-related C3 botulinum toxin substrate 3 [Source... [more]
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BLAST of Ras-related C3 botulinum toxin substrate 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000005012.18.897e-14299.48SMESG000005012.1[more]
SMESG000005010.18.227e-10874.23SMESG000005010.1[more]
SMESG000024961.14.957e-8662.18SMESG000024961.1[more]
SMESG000024968.12.987e-7959.07SMESG000024968.1[more]
SMESG000005013.12.518e-7053.37SMESG000005013.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30000430 ID=SMED30000430|Name=Ras-related C3 botulinum toxin substrate 1|organism=Schmidtea mediterranea sexual|type=transcript|length=743bp
ATTAATTTCAAAAATAATAAGTGGTAGAAATAATAATTGCTTTATTTCGT
ATTTTTTACTGATAAATGCGAAGTATTAAATGTGTGGTCATTGGGGATGG
TGCAGTTGGGAAAACATGCATACTCGTAAGTTTCACAACAGATGTGTTTT
CTTTCAGTCCCATTCCTACAGTTTTTGATAACATGTCGGCGAATATGATG
ATCGATGGAAAGCCTATCAATCTTGGTCTATGGGATACTGCGGGGCAGGA
TGACTTTGATGGTATTCGTGTAGTGTCGTATCCACAAACCGATGTGTTTC
TAATTTGTTTTTCTCTTGTTAATAAAGTTTCATTTGTCAATGTAAAAGAA
AAATGGTTCAAAGAAGTTTCTCATTACTCAGAAAACACACCAATAATTTT
AGTTGGCACTAAACTTGATTTGAGAGACAACAAAGATTTTGATGAACATG
ACAAAGGACAGGTTTTCTCTTCTCCCGTCACATATCAACAAGGTTTGGCT
TTGTGTCAAGAAATCGGAGCAGTCAAATATATTGAATGTTCTGCTAAAAC
TCAAGAAAATTTGAAAATGGTTTTTGAAGAAGCCGTCCGAATAGTGCTGA
ATAAGACCAAAAAACGGAAACGCACAAAGTTTTGTTCGTTTTTGTAATTA
TTTCTCATTTCAATTGAAAATTTATTCAATGTTTCTGTTACTCGGATATT
TCAATCAGTGAAATTTGTTCAACATTTTCGATATTATATGCTT
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protein sequence of SMED30000430-orf-1

>SMED30000430-orf-1 ID=SMED30000430-orf-1|Name=SMED30000430-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=194bp
MRSIKCVVIGDGAVGKTCILVSFTTDVFSFSPIPTVFDNMSANMMIDGKP
INLGLWDTAGQDDFDGIRVVSYPQTDVFLICFSLVNKVSFVNVKEKWFKE
VSHYSENTPIILVGTKLDLRDNKDFDEHDKGQVFSSPVTYQQGLALCQEI
GAVKYIECSAKTQENLKMVFEEAVRIVLNKTKKRKRTKFCSFL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000421tail
Vocabulary: INTERPRO
TermDefinition
IPR005225Small_GTP-bd_dom
IPR003578Small_GTPase_Rho
IPR027417P-loop_NTPase
IPR001806Small_GTPase
Vocabulary: biological process
TermDefinition
GO:0007264small GTPase mediated signal transduction
GO:0010592positive regulation of lamellipodium assembly
GO:0010762regulation of fibroblast migration
GO:0010811positive regulation of cell-substrate adhesion
GO:0014041regulation of neuron maturation
GO:0016358dendrite development
GO:0016477cell migration
GO:0016601Rac protein signal transduction
GO:0021799cerebral cortex radially oriented cell migration
GO:0021831embryonic olfactory bulb interneuron precursor migration
GO:0021894cerebral cortex GABAergic interneuron development
GO:0022604regulation of cell morphogenesis
GO:0030032lamellipodium assembly
GO:0030036actin cytoskeleton organization
GO:0030041actin filament polymerization
GO:0030334regulation of cell migration
GO:0030838positive regulation of actin filament polymerization
GO:0031529ruffle organization
GO:0032707negative regulation of interleukin-23 production
GO:0034446substrate adhesion-dependent cell spreading
GO:0035567non-canonical Wnt signaling pathway
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity
GO:0043652engulfment of apoptotic cell
GO:0045216cell-cell junction organization
GO:0045453bone resorption
GO:0045740positive regulation of DNA replication
GO:0048168regulation of neuronal synaptic plasticity
GO:0048532anatomical structure arrangement
GO:0048812neuron projection morphogenesis
GO:0048813dendrite morphogenesis
GO:0048870cell motility
GO:0048873homeostasis of number of cells within a tissue
GO:0051496positive regulation of stress fiber assembly
GO:0051668localization within membrane
GO:0051894positive regulation of focal adhesion assembly
GO:0051932synaptic transmission, GABAergic
GO:0060071Wnt signaling pathway, planar cell polarity pathway
GO:0060263regulation of respiratory burst
GO:0060999positive regulation of dendritic spine development
GO:0071260cellular response to mechanical stimulus
GO:0071526semaphorin-plexin signaling pathway
GO:0071542dopaminergic neuron differentiation
GO:0072659protein localization to plasma membrane
GO:0090023positive regulation of neutrophil chemotaxis
GO:0090103cochlea morphogenesis
GO:0097178ruffle assembly
GO:1900026positive regulation of substrate adhesion-dependent cell spreading
GO:1904948midbrain dopaminergic neuron differentiation
GO:0001934positive regulation of protein phosphorylation
GO:0002093auditory receptor cell morphogenesis
GO:0002551mast cell chemotaxis
GO:0003382epithelial cell morphogenesis
GO:0006897endocytosis
GO:0006911phagocytosis, engulfment
GO:0006935chemotaxis
GO:0006972hyperosmotic response
GO:0007010cytoskeleton organization
GO:0007015actin filament organization
GO:0007155cell adhesion
GO:0007186G-protein coupled receptor signaling pathway
GO:0007411axon guidance
GO:0008283cell proliferation
GO:0008361regulation of cell size
Vocabulary: molecular function
TermDefinition
GO:0005525GTP binding
GO:0017137Rab GTPase binding
GO:0019899enzyme binding
GO:0019901protein kinase binding
GO:0030742GTP-dependent protein binding
GO:0031996thioesterase binding
GO:0042826histone deacetylase binding
GO:0051022Rho GDP-dissociation inhibitor binding
GO:0051117ATPase binding
GO:0000166nucleotide binding
GO:0003924GTPase activity
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0019897extrinsic component of plasma membrane
GO:0030027lamellipodium
GO:0031012extracellular matrix
GO:0031410cytoplasmic vesicle
GO:0031901early endosome membrane
GO:0032587ruffle membrane
GO:0036464cytoplasmic ribonucleoprotein granule
GO:0042470melanosome
GO:0042995cell projection
GO:0043197dendritic spine
GO:0060091kinocilium
GO:0070062extracellular exosome
GO:0000139Golgi membrane
GO:0000242pericentriolar material
GO:0001891phagocytic cup
GO:0005634nucleus
GO:0005737cytoplasm
GO:0005802trans-Golgi network
GO:0005829cytosol
GO:0005884actin filament
GO:0005886plasma membrane
GO:0005925focal adhesion
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00449RASTRNSFRMNGcoord: 4..25
score: 46.95
coord: 44..66
score: 43.89
coord: 27..43
score: 23.89
coord: 106..119
score: 52.3
coord: 155..177
score: 36.79
NoneNo IPR availableSMARTSM00174rho_sub_3coord: 6..180
e-value: 4.9E-100
score: 348.3
NoneNo IPR availableSMARTSM00175rab_sub_5coord: 4..180
e-value: 2.9E-25
score: 99.9
NoneNo IPR availableSMARTSM00173ras_sub_4coord: 1..180
e-value: 1.5E-15
score: 67.7
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 1..182
e-value: 2.6E-66
score: 224.3
NoneNo IPR availablePANTHERPTHR24072RHO FAMILY GTPASEcoord: 1..190
NoneNo IPR availablePANTHERPTHR24072:SF291coord: 1..190
NoneNo IPR availableCDDcd00157Rhocoord: 4..176
e-value: 5.27298E-98
score: 279.429
IPR001806Small GTPasePFAMPF00071Rascoord: 5..178
e-value: 6.7E-52
score: 175.4
IPR005225Small GTP-binding protein domainTIGRFAMTIGR00231TIGR00231coord: 1..132
e-value: 7.1E-32
score: 108.4
IPR003578Small GTPase RhoPROSITEPS51420RHOcoord: 1..177
score: 23.211
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 3..178