TPR_REGION domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30000421 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13
Homology
BLAST of TPR_REGION domain-containing protein vs. Ensembl Human
Match: TTC6 (tetratricopeptide repeat domain 6 [Source:HGNC Symbol;Acc:HGNC:19739]) HSP 1 Score: 702.975 bits (1813), Expect = 0.000e+0 Identity = 391/1014 (38.56%), Postives = 607/1014 (59.86%), Query Frame = 2
Query: 1364 DLPENIE--PVL---DEVDEEFRGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGD-FEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQ-SPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
D PE ++ P L D V+ + + + EVK +++++ + + AF RRGA+YRK+G L +A D+ I +EP + AYW RHL++L +KI A++DLN I K +KN AY S+A IY DI+LAI N +QAI+ +P D++ Y +R E+YE + LA++D+++ I P A++K GL+Y E W A +DF+++L N++A +RG AY K + +++A DFSA IHLDPNN+LA + RGCL RK+ P+ A++D+S+S L+ EN+ +++RGI+YA K + AI DFE VI + + A+VN+GLI+ D + +++ + + DP I++Y CRAE YF+++K + A+ +++RAIHL PD Y+ RG + L M ++A + Q AE+ L + SP+QQAL++SF +++D+AI+ L + + + + LL QMKAKR K+A+ L+ + ++ +A+ + + CY+E N + + +F+ VK NP+ AE++Y +G C+++L K ILD NRA+ +NP+ YQAYL+R +G K +Y+KAILNCN+ + I P +RAYLYRGVLKY K Y LAI D T AI +D N AF+NRA+C+ + + + A+ DY IVLL+ + ++NRGL+Y+ELG AL DF +A I + + + +CHH++ +EA+ FT L +P F+ A V RGN +M+Y + A KD+ L I+ ++ A ++ G+ QAQGKF+KAW+ FT+AI+ P + +GRA+VC+QM + A++D+N A++I + L NRGV+++ M K AMKDY AI + K +AYFNAG +Y H+ Q QA + F K ++ DP +E +N A+ K EE+ E I P A +YFNRA+ + L++Y+ AE D L + P+D V R R K G A+ DY ++
Sbjct: 869 DPPERVKEPPKLKLNDYVESDLPQEVIKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYYRGCLFRKSNPFRALQDYSVSALINDGYENLGCFLHRGIVYAHLKLWLLAICDFETVISLERTITLAYVNIGLIHLLHLDNYTEAIWQFSEAIRIDPLCIQSYLCRAETYFKLHKLKKAVNELSRAIHLQPDGIQLYIRRGQYLLMMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMAFDSFTKAVKANPDFAESFYQRGLCKVKLHK-DSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRAYLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYT-KIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFL-TNRGVIHEFMGHKQNAMKDYQDAITLNP-KYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQAL 1877 HSP 2 Score: 124.02 bits (310), Expect = 1.340e-27 Identity = 202/892 (22.65%), Postives = 348/892 (39.01%), Query Frame = 2
Query: 1508 RRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYN--QIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSV------------------LRHYPSNTEA-----------------WLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSI-XXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVV--ICFNK---DMC--FAHV---------------------------------------NLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVA-TRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVAR--CYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLF---GFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKA---YSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPK--FILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSML 3898
RRG +Y ++ V A D + I +P A +R L + AIED +L D A R Y A + S AI L P++ A R L+ ++ R AL+DY+ +I N + G+ Y +++ W LA DF +V L H + TEA +L R Y KL + + A+ + S IHL P+ Y +RG L + Y + F+I + + +S M + ++Y+ + +AI EV+ I +N+ MC A V NLGL Y E+G+ + + T + A+P + ++ R +++K + +I D NRAI L P Y+ R FY G+ A + +A +I ++ + + ++ + + Y AI L A + K S K + + A+T + L L K LN + R Y+EL Y + F I+ + + C R+ + ++ + AL INP AY+ R + G +A + + L I P ++A + G Y ++A + A FT AI D LA+ RAV N+ A+QD + + IS NRG+++ +G QNA+ D+ A + P + G + + +A F++ L DP+ ++L + N + + A +D+ +V+E + N +++ A + A+ PN + RA V ++ + A+ D N+A+ ++ +S++
Sbjct: 1024 RRGEMY-EITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYYRGCLFRKSNPFR-ALQDYSVSALINDGYENLGCFLHRGIVYAHLKLWLLAICDFETVISLERTITLAYVNIGLIHLLHLDNYTEAIWQFSEAIRIDPLCIQSYLCRAETYFKLHKLKKAVNELSRAIHLQPDGIQLYIRRGQYLLMMK-YYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAI---EVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMAFDSFTKAVKANPDFAESFYQRGLCKVKLHK-DSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRAYLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVL-LLDATETVK--------LNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFG---YNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNF-AAMQDINAAMKISTTAEF----LTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTIL-----KKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1886
BLAST of TPR_REGION domain-containing protein vs. Ensembl Human
Match: TTC6 (tetratricopeptide repeat domain 6 [Source:HGNC Symbol;Acc:HGNC:19739]) HSP 1 Score: 416.387 bits (1069), Expect = 1.744e-129 Identity = 226/587 (38.50%), Postives = 345/587 (58.77%), Query Frame = 2
Query: 2624 SPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
SP+QQAL++SF +++D+AI+ L + + + + LL QMKAKR K+A+ L+ + ++ +A+ + + CY+E N + + +F+ VK NP+ AE++Y +G C+++L K ILD NRA+ +NP+ YQAYL+R +G K +Y+KAILNCN+ + I P +RAYLYRGVLKY K Y LAI D T AI +D N AF+NRA+C+ + + + A+ DY IVLL+ + ++NRGL+Y+ELG AL DF +A I + + + +CHH++ +EA+ FT L +P F+ A V RGN +M+Y + A KD+ L I+ ++ A ++ G+ QAQGKF+KAW+ FT+AI+ P + +GRA+VC+QM + A++D+N A++I + L NRGV+++ M K AMKDY AI + K +AYFNAG +Y H+ Q QA + F K ++ DP +E +N A+ K EE+ E I P A +YFNRA+ + L++Y+ AE D L + P+D V R R K G A+ DY ++
Sbjct: 9 SPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMAFDSFTKAVKANPDFAESFYQRGLCKVKLHK-DSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRAYLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYT-KIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFL-TNRGVIHEFMGHKQNAMKDYQDAITLNP-KYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQAL 591 HSP 2 Score: 115.546 bits (288), Expect = 1.406e-25 Identity = 130/516 (25.19%), Postives = 216/516 (41.86%), Query Frame = 2
Query: 1514 GALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNT---EAWLHRGTAYAKLQQWQDALTDF-SAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRG---ILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKP--SVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRAL 3034
G Y + G L A A+ PD ++++R L + +K +I D N + + + AY SR Y G S AI N ++AI++ P+ AY R L N +LA+ D I + N+ A L Y I + Q+A D+ VL + T +L+RG Y +L Q+ AL DF A + N L + C R E A+ F+ +L + + +Y+ RG + Y + +A DF + N A ++ G +G F+K+ + T + DP AY RA QM A++DIN A+ + + F RG + MG + A + A ++ + ++ + + QA D A + P L+N T K++++A F +E P A + F A Y LK Y+ ++ + + + PN A Y + R ++G +++ + D N+AL
Sbjct: 91 GLCYMEEGNLQMAFDSFTKAVKANPDFAESFYQRGLCKVKLHK-DSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRAYLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLD--AYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKI-STTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMN-RAITNTILKKYEEAKEDFANVIESC----------PFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQAL 591 HSP 3 Score: 100.523 bits (249), Expect = 7.532e-21 Identity = 98/406 (24.14%), Postives = 176/406 (43.35%), Query Frame = 2
Query: 1511 RGAL-YRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVL---AYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNI---EQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCL-LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMA------AICVRQAAEISHNL-GQSPVQQALVHSFLQHYDQAID 2683
RG L Y Y +A + D+ AIS++ + A++ R L + ++QMA+ D ++L D + + +R IY G A+ + QA +S + A + + E A+ + +++ P A + G Y+ E + A KDF L P+ +A + G ++Q A F+ I DP NYLAY R + L+ + A++D + ++ + ++ E + + RG+++ A+ D++ I N A+ N G IYF F ++ Y + L DP RA + KYE+A +D I P + Y R FY + + E+A A+ ++ + +N + + L+ + Y+QA+D
Sbjct: 191 RGVLKYYNKTYKLAIT-DLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTN---RGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALD 592 HSP 4 Score: 98.2117 bits (243), Expect = 4.089e-20 Identity = 119/574 (20.73%), Postives = 233/574 (40.59%), Query Frame = 2
Query: 1568 DAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFE---VVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYE---DAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMA------AICVRQAAEISHNLGQSPVQQALVHSF--LQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKID 3247
DA +I D + + L ++ +QMA + +K + ++ ++ R G+ +I + ++AI L+P +AY R Y G A+ + N+ I++ P + A + G+ + ++LA D ++ + ++ A+ +R Y K+++ Q ALTD+ V+ LD + + +++ RG++Y Q+ A+ DF+ ++ N +C A + + +FE++V + T L +P ++ AY R +Y + E A KD +A+H+ P + G A GK + A AI +++ G++ V + ++F +Q + A+ A + +G Q K ++DAIT L PK + G Y + + ++ FS +K +P + ++ L K ++ D + P Y RA + QY A + N+ LS++P Y +R ++ KI A+ D+ +A+ ++
Sbjct: 78 DATAISADCL---YNLGLCYMEEGNLQMAFDSFTKAVKANPDFAESFYQR-GLCKVKLHKDSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRAYLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETV--------------------------------KLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHA---TAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYE-GRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAIT--------LNPKYSLAYFNAG---------NIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 594 HSP 5 Score: 95.5153 bits (236), Expect = 2.704e-19 Identity = 121/535 (22.62%), Postives = 221/535 (41.31%), Query Frame = 2
Query: 2327 NLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVA-TRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVAR--CYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLF---GFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKA---YSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPK--FILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSML 3898
NLGL Y E+G+ + + T + A+P + ++ R +++K + +I D NRAI L P Y+ R FY G+ A + +A +I ++ + + ++ + + Y AI L A + K S K + + A+T + L L K LN + R Y+EL Y + F I+ + + C R+ + ++ + AL INP AY+ R + G +A + + L I P ++A + G Y ++A + A FT AI D LA+ RAV N+ A+QD + + IS NRG+++ +G QNA+ D+ A + P + G + + +A F++ L DP+ ++L + N + + A +D+ +V+E + N +++ A + A+ PN + RA V ++ + A+ D N+A+ ++ +S++
Sbjct: 89 NLGLCYMEEGNLQMAFDSFTKAVKANPDFAESFYQRGLCKVKLHK-DSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRAYLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVL-LLDATETVK--------LNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFG---YNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFA-AMQDINAAMKISTTAEF----LTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTIL-----KKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI 600
BLAST of TPR_REGION domain-containing protein vs. Ensembl Human
Match: TTC6 (tetratricopeptide repeat domain 6 [Source:HGNC Symbol;Acc:HGNC:19739]) HSP 1 Score: 371.318 bits (952), Expect = 1.429e-113 Identity = 196/500 (39.20%), Postives = 302/500 (60.40%), Query Frame = 2
Query: 2555 MGKMEMAAICVRQAAEISHNLGQ-SPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQ 4051
M ++A + Q AE+ L + SP+QQAL++SF +++D+AI+ L + + + + LL QMKAKR K+A+ L+ + ++ +A+ + + CY+E N + + +F+ VK NP+ AE++Y +G C+++L K ILD NRA+ +NP+ YQAYL+R +G K +Y+KAILNCN+ + I P +RAYLYRGVLKY K Y LAI D T AI +D N AF+NRA+C+ + + + A+ DY IVLL+ + ++NRGL+Y+ELG AL DF +A I + + + +CHH++ +EA+ FT L +P F+ A V RGN +M+Y + A KD+ L I+ ++ A ++ G+ QAQGKF+KAW+ FT+AI+ P + +GRA+VC+QM + A++D+N A++I + L NRGV+++ M K AMKDY AI + K +AYFNAG +Y H+ Q Q
Sbjct: 2 MKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMAFDSFTKAVKANPDFAESFYQRGLCKVKLHK-DSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRAYLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYT-KIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFL-TNRGVIHEFMGHKQNAMKDYQDAITLNP-KYSLAYFNAGNIYFHHRQFSQ 497 HSP 2 Score: 98.5969 bits (244), Expect = 2.297e-20 Identity = 99/361 (27.42%), Postives = 155/361 (42.94%), Query Frame = 2
Query: 1514 GALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNT---EAWLHRGTAYAKLQQWQDALTDF-SAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRG---ILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMA 2575
G Y + G L A A+ PD ++++R L + +K +I D N + + + AY SR Y G S AI N ++AI++ P+ AY R L N +LA+ D I + N+ A L Y I + Q+A D+ VL + T +L+RG Y +L Q+ AL DF A + N L + C R E A+ F+ +L + + +Y+ RG + Y + +A DF + N A ++ G +G F+K+ + T + DP AY RA QM A++DIN A+ + + F RG + MG + A
Sbjct: 108 GLCYMEEGNLQMAFDSFTKAVKANPDFAESFYQRGLCKVKLHK-DSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRAYLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLD--AYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKI-STTAEFLTNRGVIHEFMGHKQNA 464 HSP 3 Score: 80.8777 bits (198), Expect = 1.001e-14 Identity = 96/389 (24.68%), Postives = 162/389 (41.65%), Query Frame = 2
Query: 2327 NLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVA-TRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVAR--CYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATL---FGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKA---YSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQP 3466
NLGL Y E+G+ + + T + A+P + ++ R +++K + +I D NRAI L P Y+ R FY G+ A + +A +I ++ + + ++ + + Y AI L A + K S K + + A+T + L L K LN + R Y+EL Y + F I+ + + C R+ + ++ + AL INP AY+ R +G +A + + L I P ++A + G Y ++A + A FT AI D LA+ RAV N+ A+QD + + IS NRG+++ +G QNA+ D+ A + P
Sbjct: 106 NLGLCYMEEGNLQMAFDSFTKAVKANPDFAESFYQRGLCKVKLHK-DSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRAYLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVL-LLDATETVK--------LNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFG---YNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFA-AMQDINAAMKISTTAEF----LTNRGVIHEFMGHKQNAMKDYQDAITLNP 476 HSP 4 Score: 78.9518 bits (193), Expect = 3.669e-14 Identity = 70/326 (21.47%), Postives = 137/326 (42.02%), Query Frame = 2
Query: 1568 DAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVV---------ICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYE---DAIKDINRAIHLFP 2509
DA +I D + + L ++ +QMA + +K + ++ ++ R G+ +I + ++AI L+P +AY R Y G A+ + N+ I++ P + A + G+ + ++LA D ++ + ++ A+ +R Y K+++ Q ALTD+ V+ LD + + +++ RG++Y Q+ A+ DF+ +C MC +N +FE++V + T L +P ++ AY R +Y + E A KD +A+H+ P
Sbjct: 95 DATAISADCL---YNLGLCYMEEGNLQMAFDSFTKAVKANPDFAESFYQR-GLCKVKLHKDSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRAYLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETV--------------------------------KLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRIN---------EFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINP 375 HSP 5 Score: 77.411 bits (189), Expect = 1.101e-13 Identity = 72/294 (24.49%), Postives = 130/294 (44.22%), Query Frame = 2
Query: 1511 RGAL-YRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVL---AYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNI---EQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCL-LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEK 2368
RG L Y Y +A + D+ AIS++ + A++ R L + ++QMA+ D ++L D + + +R IY G A+ + QA +S + A + + E A+ + +++ P A + G Y+ E + A KDF L P+ +A + G ++Q A F+ I DP NYLAY R + L+ + A++D + ++ + ++ E + + RG+++ A+ D++ I N A+ N G IYF F +
Sbjct: 208 RGVLKYYNKTYKLAIT-DLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTN---RGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQ 497
BLAST of TPR_REGION domain-containing protein vs. Ensembl Human
Match: TTC6 (tetratricopeptide repeat domain 6 [Source:HGNC Symbol;Acc:HGNC:19739]) HSP 1 Score: 266.159 bits (679), Expect = 1.132e-76 Identity = 154/423 (36.41%), Postives = 233/423 (55.08%), Query Frame = 2
Query: 3128 EVLSIEPRCLR----AYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+ +I CL Y+ G L+ Y LAI D T AI +D N AF+NRA+C+ + + + A+ DY IVLL+ + ++NRGL+Y+ELG AL DF +A I + + + +CHH++ +EA+ FT L +P F+ A V RGN +M+Y + A KD+ L I+ ++ A ++ G+ QAQGKF+KAW+ FT+AI+ P + +GRA+VC+QM + A++D+N A++I + L NRGV+++ M K AMKDY AI + K +AYFNAG +Y H+ Q QA + F K ++ DP +E +N A+ K EE+ E I P A +YFNRA+ + L++Y+ AE D L + P+D V R R K G A+ DY ++
Sbjct: 95 DATAISADCLYNLGLCYMEEGNLQ---MTYKLAITDLTTAISMDKNSYTAFYNRALCYT-KIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFL-TNRGVIHEFMGHKQNAMKDYQDAITLNP-KYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQAL 511 HSP 2 Score: 127.487 bits (319), Expect = 8.745e-30 Identity = 138/586 (23.55%), Postives = 236/586 (40.27%), Query Frame = 2
Query: 2555 MGKMEMAAICVRQAAEISHNLGQ-SPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKN----YKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGD---VQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRI 4288
M ++A + Q AE+ L + SP+QQAL++SF +++D+AI+ L + + + + LL QMKAKR K+A+ L+ + ++ +A+ + + CY+E N YK + + + ++ N A+Y++ C ++ +++ + D L +L+ E + L +L RG++ ++ Y A++DF +A I A+C + +E+A+ ++ L I+ AY+ RG Y+E G + A DF++A I P + G ++A FT +D DPK LA R V C Q F DI A K + L R ++ M A+KD +AI + P+ S+ Y N G +Y R A ++KA+ + N + E+A E F +ES P A + N A Y + E + E +N+++SL PN A +Y RA V + +EA D+ L +
Sbjct: 2 MKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVL--------------------------LLDATETVK-----LNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHH-RINEFEEAVNFFTWALKINPCF---LDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVV------------------------------------CLQMGNNFAAMQDI--NAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDP-ENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDL 513 HSP 3 Score: 99.7525 bits (247), Expect = 8.802e-21 Identity = 95/399 (23.81%), Postives = 174/399 (43.61%), Query Frame = 2
Query: 1529 KMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVL---AYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNI---EQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCL-LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMA------AICVRQAAEISHNL-GQSPVQQALVHSFLQHYDQAID 2683
+M Y +A + D+ AIS++ + A++ R L + ++QMA+ D ++L D + + +R IY G A+ + QA +S + A + + E A+ + +++ P A + G Y+ E + A KDF L P+ +A + G ++Q A F+ I DP NYLAY R + L+ + A++D + ++ + ++ E + + RG+++ A+ D++ I N A+ N G IYF F ++ Y + L DP RA + KYE+A +D I P + Y R FY + + E+A A+ ++ + +N + + L+ + Y+QA+D
Sbjct: 118 QMTYKLAIT-DLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTN---RGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALD 512 HSP 4 Score: 80.4925 bits (197), Expect = 9.988e-15 Identity = 101/435 (23.22%), Postives = 177/435 (40.69%), Query Frame = 2
Query: 1751 LAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAM---MKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTA--YAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPS--VALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRAL 3034
LAI++L+ AI + + A+ RA Y + E ++AL DY ++ L + + + GL Y+ + Q+ A +DF S T L TA + ++ ++++A+ F+ + ++P AY RG SYM G AT +A DF + N A ++ G +G F+K+ + T + DP AY RA QM A++DIN A+ + + F RG + MG + A + A ++ + ++ + + QA D A + P L+N T K++++A F +E P A + F A Y LK Y+ ++ + + + PN A Y + R ++G +++ + D N+AL
Sbjct: 123 LAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAA--LISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRG----------------------------NSYMEYGHDEAT----KQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKI-STTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNR-AITNTILKKYEEAKEDFANVIESC----------PFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQAL 511 HSP 5 Score: 58.151 bits (139), Expect = 1.162e-7 Identity = 59/239 (24.69%), Postives = 94/239 (39.33%), Query Frame = 2
Query: 1511 RGALYRKMGYLVA---ASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIH----------------------------------LDPNNYLAY 2116
RG Y + G+ A A KD A+ I P I A K Q A + + D LAY+ RA + G+ A+ +++ A+++S +E + R ++E G + A++DY I L P LA G Y + Q+ A+ FS L+ P N ++R L+++++A DF+ VI L PN+ L Y
Sbjct: 250 RGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVY 487
BLAST of TPR_REGION domain-containing protein vs. Ensembl Human
Match: TTC6 (tetratricopeptide repeat domain 6 [Source:HGNC Symbol;Acc:HGNC:19739]) HSP 1 Score: 266.159 bits (679), Expect = 1.132e-76 Identity = 154/423 (36.41%), Postives = 233/423 (55.08%), Query Frame = 2
Query: 3128 EVLSIEPRCLR----AYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+ +I CL Y+ G L+ Y LAI D T AI +D N AF+NRA+C+ + + + A+ DY IVLL+ + ++NRGL+Y+ELG AL DF +A I + + + +CHH++ +EA+ FT L +P F+ A V RGN +M+Y + A KD+ L I+ ++ A ++ G+ QAQGKF+KAW+ FT+AI+ P + +GRA+VC+QM + A++D+N A++I + L NRGV+++ M K AMKDY AI + K +AYFNAG +Y H+ Q QA + F K ++ DP +E +N A+ K EE+ E I P A +YFNRA+ + L++Y+ AE D L + P+D V R R K G A+ DY ++
Sbjct: 95 DATAISADCLYNLGLCYMEEGNLQ---MTYKLAITDLTTAISMDKNSYTAFYNRALCYT-KIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFL-TNRGVIHEFMGHKQNAMKDYQDAITLNP-KYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQAL 511 HSP 2 Score: 127.487 bits (319), Expect = 8.745e-30 Identity = 138/586 (23.55%), Postives = 236/586 (40.27%), Query Frame = 2
Query: 2555 MGKMEMAAICVRQAAEISHNLGQ-SPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKN----YKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGD---VQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRI 4288
M ++A + Q AE+ L + SP+QQAL++SF +++D+AI+ L + + + + LL QMKAKR K+A+ L+ + ++ +A+ + + CY+E N YK + + + ++ N A+Y++ C ++ +++ + D L +L+ E + L +L RG++ ++ Y A++DF +A I A+C + +E+A+ ++ L I+ AY+ RG Y+E G + A DF++A I P + G ++A FT +D DPK LA R V C Q F DI A K + L R ++ M A+KD +AI + P+ S+ Y N G +Y R A ++KA+ + N + E+A E F +ES P A + N A Y + E + E +N+++SL PN A +Y RA V + +EA D+ L +
Sbjct: 2 MKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVL--------------------------LLDATETVK-----LNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHH-RINEFEEAVNFFTWALKINPCF---LDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVV------------------------------------CLQMGNNFAAMQDI--NAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDP-ENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDL 513 HSP 3 Score: 99.7525 bits (247), Expect = 8.802e-21 Identity = 95/399 (23.81%), Postives = 174/399 (43.61%), Query Frame = 2
Query: 1529 KMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVL---AYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNI---EQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCL-LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMA------AICVRQAAEISHNL-GQSPVQQALVHSFLQHYDQAID 2683
+M Y +A + D+ AIS++ + A++ R L + ++QMA+ D ++L D + + +R IY G A+ + QA +S + A + + E A+ + +++ P A + G Y+ E + A KDF L P+ +A + G ++Q A F+ I DP NYLAY R + L+ + A++D + ++ + ++ E + + RG+++ A+ D++ I N A+ N G IYF F ++ Y + L DP RA + KYE+A +D I P + Y R FY + + E+A A+ ++ + +N + + L+ + Y+QA+D
Sbjct: 118 QMTYKLAIT-DLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTN---RGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALD 512 HSP 4 Score: 80.4925 bits (197), Expect = 9.988e-15 Identity = 101/435 (23.22%), Postives = 177/435 (40.69%), Query Frame = 2
Query: 1751 LAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAM---MKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTA--YAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPS--VALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRAL 3034
LAI++L+ AI + + A+ RA Y + E ++AL DY ++ L + + + GL Y+ + Q+ A +DF S T L TA + ++ ++++A+ F+ + ++P AY RG SYM G AT +A DF + N A ++ G +G F+K+ + T + DP AY RA QM A++DIN A+ + + F RG + MG + A + A ++ + ++ + + QA D A + P L+N T K++++A F +E P A + F A Y LK Y+ ++ + + + PN A Y + R ++G +++ + D N+AL
Sbjct: 123 LAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAA--LISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRG----------------------------NSYMEYGHDEAT----KQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKI-STTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNR-AITNTILKKYEEAKEDFANVIESC----------PFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQAL 511 HSP 5 Score: 58.151 bits (139), Expect = 1.162e-7 Identity = 59/239 (24.69%), Postives = 94/239 (39.33%), Query Frame = 2
Query: 1511 RGALYRKMGYLVA---ASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIH----------------------------------LDPNNYLAY 2116
RG Y + G+ A A KD A+ I P I A K Q A + + D LAY+ RA + G+ A+ +++ A+++S +E + R ++E G + A++DY I L P LA G Y + Q+ A+ FS L+ P N ++R L+++++A DF+ VI L PN+ L Y
Sbjct: 250 RGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVY 487
BLAST of TPR_REGION domain-containing protein vs. Ensembl Celegans
Match: ogt-1 (UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase [Source:UniProtKB/Swiss-Prot;Acc:O18158]) HSP 1 Score: 84.3445 bits (207), Expect = 6.281e-16 Identity = 99/415 (23.86%), Postives = 170/415 (40.96%), Query Frame = 2
Query: 2882 LELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA 4120
+ KN +KS +K+N AEAY + G G+++ + + A+ + P AY+ A +A+ L I P C+R+ L G L + A + +AI+ +A+ N FN++ + + AI + + + AYIN G V E A+ ++RA + N V + +++ + AI + + +D P F A + N + S A + Y LE+ H D+ NL ++ QGK + A ++ A+E +P A + Q LN A+ EAIRI P + Y N G + M D A+ YN+AI I A+ N ++ + +A++ + ++ P + NLA
Sbjct: 170 FQTKNLEKSMQYSMLAIKVNNQCAEAYSNLGNYYKEKGQLQDALENYKLAVKLKPEFIDAYINLAAALVSGGDLEQAVTAYFNALQINPDLYCVRSDL--GNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVFNSQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVSAYLRALNLSGNHAVVHGNLACVYYEQGLIDLAIDTYKKAIDLQPHFPDAYCNLANALKEKGSVVE---AEQMYMKALELCPTHADSQNNLANIKREQGKIEDATRLYLKALEIYPEFAAAHSNLASILQQQGKLNDAILHYKEAIRIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQINPAFAD-AHSNLASIHKDAGNMAEAIQSYSTALKLKPDFPDAYCNLA 574 HSP 2 Score: 74.7146 bits (182), Expect = 5.087e-13 Identity = 98/430 (22.79%), Postives = 178/430 (41.40%), Query Frame = 2
Query: 3101 YTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
Y +A CN V +P L L + ++ K +++ AIK++ C A+ N + EK + A+++Y + + + AYIN + GD++ A+ + A I P+ V +G + L+EA + + ++ P+F +A + G VF NS LA + + +D LDA +NL G K IF A+ + ++ +L+G N A+ + + +Y +G++ +A+ Y KAI + P AY N + +A + + K +E P NLA + Q K+E++ +++ + P A + N A++L + +A L + +RIAP G+ + GDS A+ Y ++ I
Sbjct: 141 YVEAEKYCNLVFQSDPNNLPTLLLLSAINFQTKNLEKSMQYSMLAIKVNNQCAEAYSNLGNYYK-EKGQLQDALENYKLAVKLKPEF---IDAYINLAAALVSGGDLEQAVTAYFNALQINPDLYCVRSDLGNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVF---NSQGEIWLAIHHFEKAVTLDPNFLDAYINL-------GNVLKEARIFDRAVSAY--------------LRALNLSG-----NHAV-VHGNLACVYYEQGLID-------LAIDTYKKAIDLQP-HFPDAYCNLANALKEKGSVVEAEQMYMKALELCPTHADSQNNLANIKREQGKIEDATRLYLKALEIYPEFAAAHSNLASILQQQGKLNDAILHYKEAIRIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQI 528 HSP 3 Score: 60.8474 bits (146), Expect = 8.255e-9 Identity = 77/364 (21.15%), Postives = 148/364 (40.66%), Query Frame = 2
Query: 1637 NKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNI-MSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHV----NLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKP 2713
++Q A+E+ L +K ++ AY + A S GD+ A++ A++++PD S L + G A Y + I QP +A G + + + LA F + P+ +A+++ G + + + A++ + ++L N+ + + C+ + + D +I ++ + Y + A ++ S +V+ E + ++C H NL I E+G E + + L P + A+ A Q K DAI AI + P ++ Y G+ MG A C +A +I+ + A +H + +AI + A + KP
Sbjct: 207 GQLQDALENYKLAVKLKPEFIDAYINLAAALVSGGDLEQAVTAYFNALQINPDLYCVRSDLGNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVFNSQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVSAYLRALNLSGNHAVVHGNLACVYYEQ----GLIDLAIDTYKKAIDLQPHFPDAYCNLANALKEKGS--VVEAEQMYMKALELCPTHADSQNNLANIKREQGKIEDATRLYLKALEIYPEFAAAHSNLASILQQQGKLNDAILHYKEAIRIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQINPAFADAHSNLASIHKDAGNMAEAIQSYSTALKLKP 564 HSP 4 Score: 60.8474 bits (146), Expect = 9.531e-9 Identity = 92/455 (20.22%), Postives = 188/455 (41.32%), Query Frame = 2
Query: 1667 NLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI------SH-NLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCR 2983
NL+ + D N + + I T ++ ++ AI+++ +EAYS Y++ G+ + ALE+Y ++L+P A Y+N+ ++ D + Y + N + + R G + + ++A + I P +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A + +A+ L P ++ + GK+E A +A EI +H NL QQ ++ + HY +AI R P+ A + +G T + AI + ++ P A+ + +A + + N ++ ++S +K+ P+ +AY + C
Sbjct: 149 NLVFQSDPNNLPTLLLLSAINFQTKNLEKSMQYSMLAIKVNNQCAEAYSNLGNYYKEKGQLQDALENYKLAVKLKPEFIDA-------YINLAAALVSGGDLEQAVTAYFNALQINPDLYCVRSDLGNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVFNSQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVSAYLRALNLSGNHAVVHGNLACVYYEQGLIDLAIDTYKKAIDLQPHFPDAYCNLANALKEKGSVVEAEQMYMKALELCPTHADSQNNLANIKREQGKIEDATRLYLKALEIYPEFAAAHSNLASILQQQGKLNDAILHYKEAI-------RIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQ----------INPAFADAHSNLASIHKDAGNMAEAIQSYSTALKLKPDFPDAYCNLAHCH 577
BLAST of TPR_REGION domain-containing protein vs. Ensembl Celegans
Match: ogt-1 (UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase [Source:UniProtKB/Swiss-Prot;Acc:O18158]) HSP 1 Score: 84.3445 bits (207), Expect = 6.281e-16 Identity = 99/415 (23.86%), Postives = 170/415 (40.96%), Query Frame = 2
Query: 2882 LELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA 4120
+ KN +KS +K+N AEAY + G G+++ + + A+ + P AY+ A +A+ L I P C+R+ L G L + A + +AI+ +A+ N FN++ + + AI + + + AYIN G V E A+ ++RA + N V + +++ + AI + + +D P F A + N + S A + Y LE+ H D+ NL ++ QGK + A ++ A+E +P A + Q LN A+ EAIRI P + Y N G + M D A+ YN+AI I A+ N ++ + +A++ + ++ P + NLA
Sbjct: 170 FQTKNLEKSMQYSMLAIKVNNQCAEAYSNLGNYYKEKGQLQDALENYKLAVKLKPEFIDAYINLAAALVSGGDLEQAVTAYFNALQINPDLYCVRSDL--GNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVFNSQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVSAYLRALNLSGNHAVVHGNLACVYYEQGLIDLAIDTYKKAIDLQPHFPDAYCNLANALKEKGSVVE---AEQMYMKALELCPTHADSQNNLANIKREQGKIEDATRLYLKALEIYPEFAAAHSNLASILQQQGKLNDAILHYKEAIRIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQINPAFAD-AHSNLASIHKDAGNMAEAIQSYSTALKLKPDFPDAYCNLA 574 HSP 2 Score: 74.7146 bits (182), Expect = 5.087e-13 Identity = 98/430 (22.79%), Postives = 178/430 (41.40%), Query Frame = 2
Query: 3101 YTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
Y +A CN V +P L L + ++ K +++ AIK++ C A+ N + EK + A+++Y + + + AYIN + GD++ A+ + A I P+ V +G + L+EA + + ++ P+F +A + G VF NS LA + + +D LDA +NL G K IF A+ + ++ +L+G N A+ + + +Y +G++ +A+ Y KAI + P AY N + +A + + K +E P NLA + Q K+E++ +++ + P A + N A++L + +A L + +RIAP G+ + GDS A+ Y ++ I
Sbjct: 141 YVEAEKYCNLVFQSDPNNLPTLLLLSAINFQTKNLEKSMQYSMLAIKVNNQCAEAYSNLGNYYK-EKGQLQDALENYKLAVKLKPEF---IDAYINLAAALVSGGDLEQAVTAYFNALQINPDLYCVRSDLGNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVF---NSQGEIWLAIHHFEKAVTLDPNFLDAYINL-------GNVLKEARIFDRAVSAY--------------LRALNLSG-----NHAV-VHGNLACVYYEQGLID-------LAIDTYKKAIDLQP-HFPDAYCNLANALKEKGSVVEAEQMYMKALELCPTHADSQNNLANIKREQGKIEDATRLYLKALEIYPEFAAAHSNLASILQQQGKLNDAILHYKEAIRIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQI 528 HSP 3 Score: 60.8474 bits (146), Expect = 8.255e-9 Identity = 77/364 (21.15%), Postives = 148/364 (40.66%), Query Frame = 2
Query: 1637 NKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNI-MSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHV----NLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKP 2713
++Q A+E+ L +K ++ AY + A S GD+ A++ A++++PD S L + G A Y + I QP +A G + + + LA F + P+ +A+++ G + + + A++ + ++L N+ + + C+ + + D +I ++ + Y + A ++ S +V+ E + ++C H NL I E+G E + + L P + A+ A Q K DAI AI + P ++ Y G+ MG A C +A +I+ + A +H + +AI + A + KP
Sbjct: 207 GQLQDALENYKLAVKLKPEFIDAYINLAAALVSGGDLEQAVTAYFNALQINPDLYCVRSDLGNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVFNSQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVSAYLRALNLSGNHAVVHGNLACVYYEQ----GLIDLAIDTYKKAIDLQPHFPDAYCNLANALKEKGS--VVEAEQMYMKALELCPTHADSQNNLANIKREQGKIEDATRLYLKALEIYPEFAAAHSNLASILQQQGKLNDAILHYKEAIRIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQINPAFADAHSNLASIHKDAGNMAEAIQSYSTALKLKP 564 HSP 4 Score: 60.8474 bits (146), Expect = 9.531e-9 Identity = 92/455 (20.22%), Postives = 188/455 (41.32%), Query Frame = 2
Query: 1667 NLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI------SH-NLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCR 2983
NL+ + D N + + I T ++ ++ AI+++ +EAYS Y++ G+ + ALE+Y ++L+P A Y+N+ ++ D + Y + N + + R G + + ++A + I P +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A + +A+ L P ++ + GK+E A +A EI +H NL QQ ++ + HY +AI R P+ A + +G T + AI + ++ P A+ + +A + + N ++ ++S +K+ P+ +AY + C
Sbjct: 149 NLVFQSDPNNLPTLLLLSAINFQTKNLEKSMQYSMLAIKVNNQCAEAYSNLGNYYKEKGQLQDALENYKLAVKLKPEFIDA-------YINLAAALVSGGDLEQAVTAYFNALQINPDLYCVRSDLGNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVFNSQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVSAYLRALNLSGNHAVVHGNLACVYYEQGLIDLAIDTYKKAIDLQPHFPDAYCNLANALKEKGSVVEAEQMYMKALELCPTHADSQNNLANIKREQGKIEDATRLYLKALEIYPEFAAAHSNLASILQQQGKLNDAILHYKEAI-------RIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQ----------INPAFADAHSNLASIHKDAGNMAEAIQSYSTALKLKPDFPDAYCNLAHCH 577
BLAST of TPR_REGION domain-containing protein vs. Ensembl Celegans
Match: ogt-1 (UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase [Source:UniProtKB/Swiss-Prot;Acc:O18158]) HSP 1 Score: 82.0333 bits (201), Expect = 2.990e-15 Identity = 104/434 (23.96%), Postives = 172/434 (39.63%), Query Frame = 2
Query: 2846 AANLNFLVARCYLELKNY--KKSQLA-----FSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPN--DLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA 4120
A +N A Y L NY +K QL + VK+ P +AY + + G ++Q + AL INP LY L + +A + + + +P+ A+ G + LAI F +A+ +D N + A+ N E + +++A+ Y L +S H + N VY E G + A+ + +A +QP+ D Y NL A++ +G+V A + Y LE+ H D+ NL ++ QGK + A ++ A+E +P A + Q LN A+ EAIRI P + Y N G + M D A+ YN+AI I A+ N ++ + +A++ + ++ P + NLA
Sbjct: 7 AIKVNNQCAEAYSNLGNYYKEKGQLQDALENYKLAVKLKPEFIDAYINLAAALVSGGDLEQAVTAYFNALQINPDLYCVRSDLGNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVFNSQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLK-EARIFDRAVSAYLRALNLSGN---HAVVHGNLACVYYEQGLIDLAIDTYKKAIDLQPHFPDAYC------------NLANALK-----------------EKGSVVE----------AEQMYMKALELCPTHADSQNNLANIKREQGKIEDATRLYLKALEIYPEFAAAHSNLASILQQQGKLNDAILHYKEAIRIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQINPAFAD-AHSNLASIHKDAGNMAEAIQSYSTALKLKPDFPDAYCNLA 396 HSP 2 Score: 73.1738 bits (178), Expect = 1.323e-12 Identity = 89/386 (23.06%), Postives = 161/386 (41.71%), Query Frame = 2
Query: 3233 AIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
AIK++ C A+ N + EK + A+++Y + + + AYIN + GD++ A+ + A I P+ V +G + L+EA + + ++ P+F +A + G VF NS LA + + +D LDA +NL G K IF A+ + ++ +L+G N A+ + + +Y +G++ +A+ Y KAI + P AY N + +A + + K +E P NLA + Q K+E++ +++ + P A + N A++L + +A L + +RIAP G+ + GDS A+ Y ++ I
Sbjct: 7 AIKVNNQCAEAYSNLGNYYK-EKGQLQDALENYKLAVKLKPEF---IDAYINLAAALVSGGDLEQAVTAYFNALQINPDLYCVRSDLGNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVF---NSQGEIWLAIHHFEKAVTLDPNFLDAYINL-------GNVLKEARIFDRAVSAY--------------LRALNLSG-----NHAV-VHGNLACVYYEQGLID-------LAIDTYKKAIDLQP-HFPDAYCNLANALKEKGSVVEAEQMYMKALELCPTHADSQNNLANIKREQGKIEDATRLYLKALEIYPEFAAAHSNLASILQQQGKLNDAILHYKEAIRIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQI 350 HSP 3 Score: 61.2326 bits (147), Expect = 5.733e-9 Identity = 97/398 (24.37%), Postives = 154/398 (38.69%), Query Frame = 2
Query: 2285 VVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLR---GDFYLAMGKMEMAAICVRQAAEIS-------HNLG-----QSPVQQALVH---------SFLQHY-------------DQAIDALLVATR--GKPSVALLNLL------GTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVL 3343
+ I N A+ NLG Y EKG + +++ + P +I AY A A E A+ A+ + PD Y +R G+ AMG++E A +C +A E NLG Q + A+ H +FL Y D+A+ A L A G +V NL G + +K AI L+P +P NL A E + +++ + +++ P HA++ + + GK++ +AL I P A+ A++ + + AIL+ E + I P AY G ++ S AI + AI+I+ A N A + + N +AIQ YS L
Sbjct: 6 LAIKVNNQCAEAYSNLGNYYKEKGQLQDALENYKLAVKLKPEFIDAYINLAAALVSGGDLEQAVTAYFNALQINPD---LYCVRSDLGNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVFNSQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVSAYLRALNLSGNHAVVHGNLACVYYEQGLIDLAIDTYKKAI--------DLQPH-----FPDAYCNL----ANALKEKGSVVEAEQMYMKALELCPTHADSQNNLANIKREQGKIEDATRLYLKALEIYPEFAAAHSNLASILQQQGKLNDAILHYKEAIRIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQINPAFADAHSNLA-SIHKDAGNMAEAIQSYSTAL 382 HSP 4 Score: 58.9214 bits (141), Expect = 3.396e-8 Identity = 86/419 (20.53%), Postives = 174/419 (41.53%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI------SH-NLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCR 2983
AI+++ +EAYS Y++ G+ + ALE+Y ++L+P A Y+N+ ++ D + Y + N + + R G + + ++A + I P +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A + +A+ L P ++ + GK+E A +A EI +H NL QQ ++ + HY +AI R P+ A + +G T + AI + ++ P A+ + +A + + N ++ ++S +K+ P+ +AY + C
Sbjct: 7 AIKVNNQCAEAYSNLGNYYKEKGQLQDALENYKLAVKLKPEFIDA-------YINLAAALVSGGDLEQAVTAYFNALQINPDLYCVRSDLGNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVFNSQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVSAYLRALNLSGNHAVVHGNLACVYYEQGLIDLAIDTYKKAIDLQPHFPDAYCNLANALKEKGSVVEAEQMYMKALELCPTHADSQNNLANIKREQGKIEDATRLYLKALEIYPEFAAAHSNLASILQQQGKLNDAILHYKEAI-------RIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQ----------INPAFADAHSNLASIHKDAGNMAEAIQSYSTALKLKPDFPDAYCNLAHCH 399 HSP 5 Score: 51.2174 bits (121), Expect = 6.470e-6 Identity = 83/400 (20.75%), Postives = 153/400 (38.25%), Query Frame = 2
Query: 2006 EAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYR---GILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDF---YLAMGKMEMAAICVRQAAEISH-------NLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAY 3166
EA+ + G Y + Q QDAL ++ + L P AY L + +++ + + N Y R G L + EA V + I A NLG ++ +G+ ++ + + DP ++ AY + ++ A+ RA++L N ++ G+ Y G +++A ++A ++ NL + ++ V Q Y +A++ L T N L + + + +DA + LE Y + +NL A + + L + ++I P A+AY + G +G I NRA+ INP A+ A++ +AI + + L ++P AY
Sbjct: 16 EAYSNLGNYYKEKGQLQDALENYKLAVKLKPEFIDAYINLAAALVSGGDL----EQAVTAYFNALQINPDLYCVRSDLGNLLKAMGRLEEAKVCYLKAIETQPQFAVAWSNLGCVFNSQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVSAYLRALNL---SGNHAVVHGNLACVYYEQGLIDLAIDTYKKAIDLQPHFPDAYCNLANALKEKGSVVEAEQMYMKALE--LCPTHADSQ----NNLANIKREQGKIEDATRLYLKALEI------YPEFAAAHSNL----ASILQQQGKLNDAILHYKEAIRIAPTFADAYSNMGNTLKEMGDSSAAIACYNRAIQINPAFADAHSNLASIHKDAGNMAEAIQSYSTALKLKPDFPDAY 392
BLAST of TPR_REGION domain-containing protein vs. Ensembl Celegans
Match: F38B6.6 (Protein O-mannosyl-transferase TMTC1 [Source:UniProtKB/Swiss-Prot;Acc:Q20144]) HSP 1 Score: 53.9138 bits (128), Expect = 1.028e-6 Identity = 49/207 (23.67%), Postives = 86/207 (41.55%), Query Frame = 2
Query: 3641 AAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAE 4261
A K+Y + +++D + AL NLG + G K A + A+ P+ I M + A K L ++ I+P S+ N GV+YQ MAM + A I ++ N V H Q Q ++ + + S P + + + + + + +I +I L+P S + N + + R++EAE
Sbjct: 451 AEKNYWNAIKLDPSYEQALNNLGNLLEKSGDSKTAESLLARAVTLRPSFAVAWMNLGISQMNLKKYYEAEKSLKNSLLIRPNSAHCLFNLGVLYQRTNRDEMAMSAWKNATRIDPSHSQ-SWTNLFVVLDHLSQCSQVIDLSYQALSSVPNESRVHMQIGSCHAKHSNFTAAENHIKSAIDLNPTSVLFHANLGILYQRMSRHKEAE 656
BLAST of TPR_REGION domain-containing protein vs. Ensembl Fly
Match: sxc (gene:FBgn0261403 transcript:FBtr0086085) HSP 1 Score: 93.9745 bits (232), Expect = 8.011e-19 Identity = 112/470 (23.83%), Postives = 194/470 (41.28%), Query Frame = 2
Query: 2861 FLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
L++ + + + KS + +K NP AEAY + G G++++ + + RA+ + P Y+ A A+ L P C+R+ L G L + A + +AI+ +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA + PN+ V + +++ + AI + R ++ P F A + N + A YN+ L + S H D+L NL ++ QG ++A ++ A+E P+ A V Q L AL EAIRIQP + Y N G + ++D A++ Y +AI I A+ N ++ + + +A++ +R ++ P + NLA LV I +LE+ NR S+ P+ + LY
Sbjct: 88 LLLSSIHFQCRRLDKSAQFSTLAIKQNPVLAEAYSNLGNVFKERGQLQEALDNYRRAVRLKPDFIDGYINLAAALVAARDMESAVQAYITALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGQVKE---AEDCYNTALRLCSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDIRMKKLVSIVTEQLEK-----NRLPSVHPHHSMLY 542 HSP 2 Score: 67.0106 bits (162), Expect = 1.435e-10 Identity = 77/341 (22.58%), Postives = 143/341 (41.94%), Query Frame = 2
Query: 3374 KAYINRGLVYLELGDVQNALHDFIRAQAIQPN--DLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+AY N G V+ E G +Q AL ++ RA ++P+ D Y+ + ++++ A++ + L ++P + GN+ + + A Y +E A NLG AQG+ A F A+ PN V + + A+ A+ + P +++++ N VY +A+ Y +AI + P AY N Q+++A +C+ + NLA + Q +EE+ +++ + P+ A + N A+VL + +EA + + +RI P G+ + D GAL+ Y ++ I
Sbjct: 119 EAYSNLGNVFKERGQLQEALDNYRRAVRLKPDFIDGYINLAAALV--AARDMESAVQAYITALQYNPDLYCVRSDLGNLL---KALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP-NFPDAYCNLANALKEKGQVKEAEDCYNTALRLCSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQI 453 HSP 3 Score: 61.6178 bits (148), Expect = 5.752e-9 Identity = 67/299 (22.41%), Postives = 125/299 (41.81%), Query Frame = 2
Query: 3479 VLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLN----------EAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTG 4345
VL ++ H + + L ++ + T + +P A + GNVF + A +Y + + +D +NL A + A + A++ +P+ + C++ SDL LK L +AI P ++ + N G V+ + +A+ + KA+ + AY N G V ++A+ + + + P + NLA VY Q ++ +I+ R+I L PN Y N AN L + + +EAE + + LR+ + L + + + G
Sbjct: 86 VLLLLSSIHFQCRRLDKSAQFSTLAIKQNPVLAEAYSNLGNVFKERGQLQE---ALDNYRRAVRLKPDFIDGYINLAAALVAARDMESAVQAYITALQYNPD---------LYCVR-SDLGNLLKALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP-NFLDAYINLGNVLKEARIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGQVKEAEDCYNTALRLCSNHADSLNNLANIKREQG 370 HSP 4 Score: 58.5362 bits (140), Expect = 5.651e-8 Identity = 84/461 (18.22%), Postives = 172/461 (37.31%), Query Frame = 2
Query: 1622 LHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI------SH-NLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
+H C ++ + + L +K++ AY + ++ G + A+ N +A+RL PD + Y A + A++ Y ++ P+ G + + + A + + P AW + G + + A+ F + LDPN AY G +L++A + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + + ++A N A+ L + ++ + G +E A +A E+ +H NL QQ + L HY +AI R +P+ A + +G T + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 93 IHFQCRRLDKSAQFSTLAIKQNPVLAEAYSNLGNVFKERGQLQEALDNYRRAVRLKPDFIDGYINLAAALVAARDMESAVQAYITALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEA-----------------------------------RIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGQVKEAEDCYNTALRLCSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAI-------RIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHC 501
BLAST of TPR_REGION domain-containing protein vs. Ensembl Fly
Match: sxc (gene:FBgn0261403 transcript:FBtr0086084) HSP 1 Score: 93.9745 bits (232), Expect = 8.011e-19 Identity = 112/470 (23.83%), Postives = 194/470 (41.28%), Query Frame = 2
Query: 2861 FLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
L++ + + + KS + +K NP AEAY + G G++++ + + RA+ + P Y+ A A+ L P C+R+ L G L + A + +AI+ +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA + PN+ V + +++ + AI + R ++ P F A + N + A YN+ L + S H D+L NL ++ QG ++A ++ A+E P+ A V Q L AL EAIRIQP + Y N G + ++D A++ Y +AI I A+ N ++ + + +A++ +R ++ P + NLA LV I +LE+ NR S+ P+ + LY
Sbjct: 88 LLLSSIHFQCRRLDKSAQFSTLAIKQNPVLAEAYSNLGNVFKERGQLQEALDNYRRAVRLKPDFIDGYINLAAALVAARDMESAVQAYITALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGQVKE---AEDCYNTALRLCSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDIRMKKLVSIVTEQLEK-----NRLPSVHPHHSMLY 542 HSP 2 Score: 67.0106 bits (162), Expect = 1.435e-10 Identity = 77/341 (22.58%), Postives = 143/341 (41.94%), Query Frame = 2
Query: 3374 KAYINRGLVYLELGDVQNALHDFIRAQAIQPN--DLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+AY N G V+ E G +Q AL ++ RA ++P+ D Y+ + ++++ A++ + L ++P + GN+ + + A Y +E A NLG AQG+ A F A+ PN V + + A+ A+ + P +++++ N VY +A+ Y +AI + P AY N Q+++A +C+ + NLA + Q +EE+ +++ + P+ A + N A+VL + +EA + + +RI P G+ + D GAL+ Y ++ I
Sbjct: 119 EAYSNLGNVFKERGQLQEALDNYRRAVRLKPDFIDGYINLAAALV--AARDMESAVQAYITALQYNPDLYCVRSDLGNLL---KALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP-NFPDAYCNLANALKEKGQVKEAEDCYNTALRLCSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQI 453 HSP 3 Score: 61.6178 bits (148), Expect = 5.752e-9 Identity = 67/299 (22.41%), Postives = 125/299 (41.81%), Query Frame = 2
Query: 3479 VLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLN----------EAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTG 4345
VL ++ H + + L ++ + T + +P A + GNVF + A +Y + + +D +NL A + A + A++ +P+ + C++ SDL LK L +AI P ++ + N G V+ + +A+ + KA+ + AY N G V ++A+ + + + P + NLA VY Q ++ +I+ R+I L PN Y N AN L + + +EAE + + LR+ + L + + + G
Sbjct: 86 VLLLLSSIHFQCRRLDKSAQFSTLAIKQNPVLAEAYSNLGNVFKERGQLQE---ALDNYRRAVRLKPDFIDGYINLAAALVAARDMESAVQAYITALQYNPD---------LYCVR-SDLGNLLKALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP-NFLDAYINLGNVLKEARIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGQVKEAEDCYNTALRLCSNHADSLNNLANIKREQG 370 HSP 4 Score: 58.5362 bits (140), Expect = 5.651e-8 Identity = 84/461 (18.22%), Postives = 172/461 (37.31%), Query Frame = 2
Query: 1622 LHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI------SH-NLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
+H C ++ + + L +K++ AY + ++ G + A+ N +A+RL PD + Y A + A++ Y ++ P+ G + + + A + + P AW + G + + A+ F + LDPN AY G +L++A + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + + ++A N A+ L + ++ + G +E A +A E+ +H NL QQ + L HY +AI R +P+ A + +G T + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 93 IHFQCRRLDKSAQFSTLAIKQNPVLAEAYSNLGNVFKERGQLQEALDNYRRAVRLKPDFIDGYINLAAALVAARDMESAVQAYITALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEA-----------------------------------RIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGQVKEAEDCYNTALRLCSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAI-------RIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHC 501
BLAST of TPR_REGION domain-containing protein vs. Ensembl Fly
Match: sxc (gene:FBgn0261403 transcript:FBtr0086086) HSP 1 Score: 93.9745 bits (232), Expect = 8.011e-19 Identity = 112/470 (23.83%), Postives = 194/470 (41.28%), Query Frame = 2
Query: 2861 FLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
L++ + + + KS + +K NP AEAY + G G++++ + + RA+ + P Y+ A A+ L P C+R+ L G L + A + +AI+ +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA + PN+ V + +++ + AI + R ++ P F A + N + A YN+ L + S H D+L NL ++ QG ++A ++ A+E P+ A V Q L AL EAIRIQP + Y N G + ++D A++ Y +AI I A+ N ++ + + +A++ +R ++ P + NLA LV I +LE+ NR S+ P+ + LY
Sbjct: 88 LLLSSIHFQCRRLDKSAQFSTLAIKQNPVLAEAYSNLGNVFKERGQLQEALDNYRRAVRLKPDFIDGYINLAAALVAARDMESAVQAYITALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGQVKE---AEDCYNTALRLCSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDIRMKKLVSIVTEQLEK-----NRLPSVHPHHSMLY 542 HSP 2 Score: 67.0106 bits (162), Expect = 1.435e-10 Identity = 77/341 (22.58%), Postives = 143/341 (41.94%), Query Frame = 2
Query: 3374 KAYINRGLVYLELGDVQNALHDFIRAQAIQPN--DLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+AY N G V+ E G +Q AL ++ RA ++P+ D Y+ + ++++ A++ + L ++P + GN+ + + A Y +E A NLG AQG+ A F A+ PN V + + A+ A+ + P +++++ N VY +A+ Y +AI + P AY N Q+++A +C+ + NLA + Q +EE+ +++ + P+ A + N A+VL + +EA + + +RI P G+ + D GAL+ Y ++ I
Sbjct: 119 EAYSNLGNVFKERGQLQEALDNYRRAVRLKPDFIDGYINLAAALV--AARDMESAVQAYITALQYNPDLYCVRSDLGNLL---KALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP-NFPDAYCNLANALKEKGQVKEAEDCYNTALRLCSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQI 453 HSP 3 Score: 61.6178 bits (148), Expect = 5.752e-9 Identity = 67/299 (22.41%), Postives = 125/299 (41.81%), Query Frame = 2
Query: 3479 VLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLN----------EAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTG 4345
VL ++ H + + L ++ + T + +P A + GNVF + A +Y + + +D +NL A + A + A++ +P+ + C++ SDL LK L +AI P ++ + N G V+ + +A+ + KA+ + AY N G V ++A+ + + + P + NLA VY Q ++ +I+ R+I L PN Y N AN L + + +EAE + + LR+ + L + + + G
Sbjct: 86 VLLLLSSIHFQCRRLDKSAQFSTLAIKQNPVLAEAYSNLGNVFKERGQLQE---ALDNYRRAVRLKPDFIDGYINLAAALVAARDMESAVQAYITALQYNPD---------LYCVR-SDLGNLLKALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP-NFLDAYINLGNVLKEARIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGQVKEAEDCYNTALRLCSNHADSLNNLANIKREQG 370 HSP 4 Score: 58.5362 bits (140), Expect = 5.651e-8 Identity = 84/461 (18.22%), Postives = 172/461 (37.31%), Query Frame = 2
Query: 1622 LHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI------SH-NLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
+H C ++ + + L +K++ AY + ++ G + A+ N +A+RL PD + Y A + A++ Y ++ P+ G + + + A + + P AW + G + + A+ F + LDPN AY G +L++A + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + + ++A N A+ L + ++ + G +E A +A E+ +H NL QQ + L HY +AI R +P+ A + +G T + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 93 IHFQCRRLDKSAQFSTLAIKQNPVLAEAYSNLGNVFKERGQLQEALDNYRRAVRLKPDFIDGYINLAAALVAARDMESAVQAYITALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETCPGFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEA-----------------------------------RIFDRAVAAYLRALNLSPNNAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGQVKEAEDCYNTALRLCSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAI-------RIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHC 501
BLAST of TPR_REGION domain-containing protein vs. Ensembl Fly
Match: CG5038 (gene:FBgn0038324 transcript:FBtr0083089) HSP 1 Score: 66.6254 bits (161), Expect = 1.513e-10 Identity = 52/221 (23.53%), Postives = 98/221 (44.34%), Query Frame = 2
Query: 3728 GKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
G KA+ + AIE +PN E L + + L+ A + + A++ P ++N G+V A+ Y KA+ + Y+N G +Y+ + +AL ++ V +P W N+ + + ++++ N+++ PN + F RANVL L+ Y EAE + + + P + G + + A+E Y+T++ I
Sbjct: 458 GNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRA-NFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAISI 677 HSP 2 Score: 51.2174 bits (121), Expect = 7.657e-6 Identity = 36/147 (24.49%), Postives = 70/147 (47.62%), Query Frame = 2
Query: 3863 EAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDP 4303
A+++ P ++ ++ N + M + A + Y++AI + A N G +Y + QL A E R +++ P A W+NL +V Q K ++++ +++ N A Y+N N+ + +RY EA + + + P P
Sbjct: 435 SALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYP-NYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQP 580
BLAST of TPR_REGION domain-containing protein vs. Ensembl Fly
Match: P58IPK (gene:FBgn0037718 transcript:FBtr0082074) HSP 1 Score: 59.6918 bits (143), Expect = 1.753e-8 Identity = 34/108 (31.48%), Postives = 54/108 (50.00%), Query Frame = 2
Query: 1787 SPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYL 2110
SP D E + + + + G+ AL Y+ + NN L + K G YL + + + A +DFS VL P A + RG + K +++ A+ DF V+ +PNN L
Sbjct: 39 SPADIENHLELGKEFLARGQLSDALTHYHAAVEGDANNYLTLFKRGTVYLALGKTRFAVQDFSRVLELKPDFMAARIQRGVVHMKSGEYEQAIQDFDQVLQEEPNNGL 146 HSP 2 Score: 56.9954 bits (136), Expect = 9.478e-8 Identity = 49/219 (22.37%), Postives = 86/219 (39.27%), Query Frame = 2
Query: 1994 PSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPT-------YIRAYPCR-----AEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHN 2614
P++ E L G + Q DALT + A + D NNYL FKRG + YLA+ A+ DF V+ D A + G+++ + G++E++++ L +P Y R P + + Q + +++AI I + + + P F R D Y+A+ +A +RQ ++ +
Sbjct: 40 PADIENHLELGKEFLARGQLSDALTHYHAAVEGDANNYLTLFKRGTV------YLALGKTRF-----------------------------AVQDFSRVLELKPDFMAARIQRGVVHMKSGEYEQAIQDFDQVLQEEPNNGLVLEHYSRLAPAQEQWVLVQQLIQYSDHQNAIPMITQLLEISPWAVPFRQARSDAYIAINDPLLAIADLRQVNRLTQD 223 HSP 3 Score: 56.9954 bits (136), Expect = 1.126e-7 Identity = 52/227 (22.91%), Postives = 94/227 (41.41%), Query Frame = 2
Query: 1370 PENIEPVLDEVDEEF--RGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAY----------------------------------------------KSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCL 1906
P +IE L E+ +EF RG L + L + D NY L +RG +Y +G A +D + + ++PD + A +R ++H+ + + AI+D + +L+++ N L ++R+ Y + D LAI++L Q RL+ D +E + K A+L G AL++ + ++ P + L
Sbjct: 40 PADIENHL-ELGKEFLARGQLSDALTHYHAAVEGDANNY-----LTLFKRGTVYLALGKTRFAVQDFSRVLELKPDFMAARIQRGVVHMKSGEYEQAIQDFDQVLQEEPNNGLVLEHYSRLAPAQEQWVLVQQLIQYSDHQNAIPMITQLLEISPWAVPFRQARSDAYIAINDPLLAIADLRQVNRLTQDSTEGHYKIAQLLYTIGHATNALKEIRECLKFDPEHKL 260 HSP 4 Score: 52.373 bits (124), Expect = 2.927e-6 Identity = 28/110 (25.45%), Postives = 55/110 (50.00%), Query Frame = 2
Query: 1628 LVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL 1957
L ++ A+ + ++ D N L R +Y + G A+ + S+ + L PD A +R ++ ++GE A++D++Q+++ +PNN L + + EQW L
Sbjct: 54 LARGQLSDALTHYHAAVEGDANNYLTLFKRGTVYLALGKTRFAVQDFSRVLELKPDFMAARIQRGVVHMKSGEYEQAIQDFDQVLQEEPNNGLVLEHYSRLAPAQEQWVL 163
BLAST of TPR_REGION domain-containing protein vs. Ensembl Zebrafish
Match: ttc6 (tetratricopeptide repeat domain 6 [Source:ZFIN;Acc:ZDB-GENE-090429-2]) HSP 1 Score: 782.326 bits (2019), Expect = 0.000e+0 Identity = 433/1138 (38.05%), Postives = 669/1138 (58.79%), Query Frame = 2
Query: 1004 LGQPPNKLDKTKSFENIRIELKRIRSCXXXXXXXXXXXXXXXXADIHNFEDWSKNRGYKKESNA-RDWITVIWDQWFDEIYPPIPDHIIDLTSDKPSETPYKNELLNREPTSVSAIQNEILDLPENIEPVLDEVDEEFRGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFE-KSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCY----LELKNYKKSQL-----AFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
L +PP L ++KS + E K + + SL + +FE + + G ++ R+W+ IWD WFDE++PP+ + + S P + L+++ + LD+ E ++ L D E EV +++ + NAF RRGALY K+GYL A +D++ AIS+EP L+ AYW RH ++L+ N A++DLN+I+ +K + A+ SRA IY G+ +LA+ + +QAI++ PDD+E Y KRA++Y++ GE LA+EDY + + P AMM HG+++ N +W ++ +DFS +L+ P N A +RG Y+KL ++ ++ D S +HL+P ++LA++ RGCLLR+ P+LA+RDFS S+L+ S EN ++++RG++Y T + + +AI DFE VI ++ AHVNLG+I K D ++++ + L ADPTY++AY CRA A++ +N A+KD+ RAIHL PD + Y++RG F+ M ++AA+C++ AAE+ LG S VQQA++ SFL + AI L A +PS L LLG T MK R+ +A+ +F L L A + +L+ CY L + S L AF++TV +NP+HAEA++ +G CR+ L + G+ D NRAL INP+ YQ +L+RA L+G + ++ KAIL+CNE + I+P+ LRA+LY+G LK+ +KAY A++D T A++ID C A++NR +CF E ++YE A++DYS+ LL+ L K INRGL+Y+EL D +AL D A +P D+ + + +GV HH+L L+EA+ ++ DP V RGNVFMDY + +R A +D+ S L ++ L A ++L + Q G F++AW+ FT+A+E +P GRA +QM + AL+D+N AI P + L+ NRG++ QL DK AMKDY AI + +AYFNA ++ +N Q EQA E + + E DP DE+ +N A+ + K+ ES++ N ++ L+P SA+ YFNRAN+ L+++Q AE D L + P D + K R D R G A+EDY+T++
Sbjct: 360 LREPPRTLTRSKSLCQLPWEHKTSKG----------RFSHLSLPVLLDFESFVTDHGGIPDTTPPREWVRNIWDTWFDEVFPPLEN----IQSSDPLPAALEENQLSQD--------EDKLDMCEVVDEGLSTADLE----------HEVAKLTQALTEGGNRNAFDRCRRGALYIKLGYLEQALEDLSAAISLEPHLLDAYWHRHSIYLLRNDPVRALDDLNVIVTNNKKHADAFMSRAEIYKQRGETTLALFSYTQAIKVKPDDAEIYFKRAKMYDKMGEILLAMEDYAKTFTIDPTRTDAMMLHGMHHFNSSKWTVSLEDFSLLLKQEPDNAIARTYRGRIYSKLGHFEKSVEDLSLAVHLNPADWLAFYHRGCLLREIMPHLALRDFSTSVLINDSAENWRAFLHRGMVYVTLQHWQQAIADFEAVIKLDRSAAVAHVNLGMICMLKMDRHYEAIRRFNNALKADPTYVKAYVCRARAFYNVNNLSKAVKDLTRAIHLKPDAYDLYIMRGKFFYEMKCFDLAALCIQYAAEMKTALGLSAVQQAVIQSFLGNDANAIVCLEQAVDTQPSPPHLILLGRTLMKEHRFTEAVETFKKALSFLGSTKAKLSPAKETAEVFYLIGVCYVTQRLLFQESGDSLLLQALDAFNSTVSLNPDHAEAHHQRGLCRIHL-QDSTGVQDFNRALKINPKFYQVHLSRAALYGAEGRHAKAILDCNEAIRIQPKSLRAHLYKGALKFYLKAYKSAVEDLTMAVQIDPACSFAYYNRGICFQ-ELQHYEMALRDYSVTLLLGCKTELELKVLINRGLLYVELNDYSSALQDLKAAAQKRPADVLIYHALGVIHHRLGQLQEAVDAYSEAARLDPFLQDCLVGRGNVFMDYGHNQARKKAQRDFLSALHLNPLCLSARISLAYNLQVLGFFQRAWNQFTVAVEVNPKCWAAYQGRAATSLQMGNKFAALQDINTAIEYNPFTEQLFTNRGLIQQLRGDKSSAMKDYQTAISLNPAYA-LAYFNAANLFFYNGQFEQACEYYSRAFELDPSDESAILNRAITHALLRKVPESLQDFNEALCLNPLSAHAYFNRANLHCSLRQFQSAERDLTQALVLEPGDALLYKLRADVRGCLGWMEEAMEDYRTAL 1462 HSP 2 Score: 55.8398 bits (133), Expect = 5.271e-7 Identity = 75/341 (21.99%), Postives = 127/341 (37.24%), Query Frame = 2
Query: 1613 RHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAEL---YEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNI-----EQWQ------------------------------LAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLL------RKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHL 2503
R LL++ N A++DL +K VL Y + I+ G + A+ S+A RL P + R + Y N + A D+ + L P CL+ Y L + W A +D ++ + + P + + +RG A+ D+ I L+P LAYF L +A Y + R F + ES+ N R I +A ++ E++ DF +C N A+ N ++ F+ + + +T L +P Y RA+ + E+A++D A+ L
Sbjct: 1132 RGLLYVELNDYSSALQDLKAAAQKRPADVLIYHALGVIHHRLGQLQEAVDAYSEAARLDPFLQDCLVGRGNVFMDYGHNQARKKAQRDFLSALHLNPL-CLSARISLAYNLQVLGFFQRAWNQFTVAVEVNPKCWAAYQGRAATSLQMGNKFAALQDINTAIEYNPFTEQLFTNRGLIQQLRGDKSSAMKDYQTAISLNPAYALAYFNAANLFFYNGQFEQACEYYS-RAFELDPSDESAILN------RAITHALLRKVPESLQDFNEALCLNPLSAHAYFNRANLHCSLRQFQSAERDLTQALVLEPGDALLYKLRADVRGCLGWMEEAMEDYRTALKL 1464
BLAST of TPR_REGION domain-containing protein vs. Ensembl Zebrafish
Match: ogt.1 (O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9631]) HSP 1 Score: 98.5969 bits (244), Expect = 3.886e-20 Identity = 122/536 (22.76%), Postives = 218/536 (40.67%), Query Frame = 2
Query: 2669 DQAIDALLVATRGKPSVALLNLLGTTQMKAKRWK--DAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
D A VA +P+ +L+ G ++ + ++ D + C++ + + P + L++ + + + +S + +K NP AEAY + G G++++ I AL + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + + + A + YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I ++LE+ NR S+ P+ + LY
Sbjct: 57 DMASSVGNVADSTEPTKRVLSFQGLAELAHREYQSGDFEAAERHCMQLWRQE-------PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSE---AEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEK-----NRLPSVHPHHSMLY 570 HSP 2 Score: 88.5817 bits (218), Expect = 4.396e-17 Identity = 98/425 (23.06%), Postives = 173/425 (40.71%), Query Frame = 2
Query: 3119 NCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPI---AYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+C ++ EP L + ++ + + T AIK + A+ N + E+ ++AI+ Y L + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP Y N + + A + YN A+ + CP + N + +E+A++ +RK +E P A NLA V Q KL+E++ + +I +SP A Y N N L ++Q Q A + ++I P +G+ A+ Y+T++
Sbjct: 100 HCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYK-ERGQLQEAIEHYRHALRLKPDF---IDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRL----CPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 513 HSP 3 Score: 77.0258 bits (188), Expect = 1.659e-13 Identity = 90/418 (21.53%), Postives = 176/418 (42.11%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
AI+ +P +EAYS +Y++ G+ + A+E Y +RL+P+ Y+N+ +AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A + N A+ L P ++ + G +E A R+A E+ NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 138 AIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 529 HSP 4 Score: 59.3066 bits (142), Expect = 4.380e-8 Identity = 94/492 (19.11%), Postives = 191/492 (38.82%), Query Frame = 2
Query: 1733 STGDISLAISNLSQAIRLSPDDSEAYSKR-------AELYE---QNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYR---GILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAY 3166
S GD++ ++ N++ DS +KR AEL Q+G+ A Q+ R +P+N ++ + + +A + ++ P EA+ + G Y + Q Q+A+ + + L P+ Y L A + ++ + + + N Y R G L + EA + I + A NLG ++ +G+ ++ + + DP ++ AY + ++ A+ RA+ L P+ + + Y G +++A R+A E+ + + A + +A + A R P+ A LN L + + ++A+ + LE P A + +A + +++ + + ++I+P A+AY + G + ++ + RA+ INP A+ A++ +AI + L ++P AY
Sbjct: 54 SEGDMASSVGNVA--------DSTEPTKRVLSFQGLAELAHREYQSGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAA----GDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVF----------PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 523 HSP 5 Score: 53.9138 bits (128), Expect = 1.648e-6 Identity = 80/377 (21.22%), Postives = 140/377 (37.14%), Query Frame = 2
Query: 1484 RPN-AFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL--AAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM----NKYEDAIKDI----------NRAIHLFPDRSNFYMLRGDFYLAMGK 2563
+PN A S G ++ G + A A++++P+ + AY + A+ L N+ + + + A +Y G I LAI +AI L P +AY A ++ G A E YN +RL P + ++ + L + EQ + A + + L +P A + + + + Q+AL + I + P AY G L++ ++D +G L T+ I N AH NL I+ + G+ +++ + L P + AY C Q+ Y++ +K + NR + P S Y L F A+ +
Sbjct: 244 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSL--NNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKE------MQDV------------------QGALQCYTR-----------AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY-CNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAE 582
BLAST of TPR_REGION domain-containing protein vs. Ensembl Zebrafish
Match: ogt.1 (O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9631]) HSP 1 Score: 98.2117 bits (243), Expect = 4.523e-20 Identity = 120/528 (22.73%), Postives = 216/528 (40.91%), Query Frame = 2
Query: 2693 VATRGKPSVALLNLLGTTQMKAKRWK--DAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
VA +P+ +L+ G ++ + ++ D + C++ + + P + L++ + + + +S + +K NP AEAY + G G++++ I AL + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + + + A + YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I ++LE+ NR S+ P+ + LY
Sbjct: 8 VADSTEPTKRVLSFQGLAELAHREYQSGDFEAAERHCMQLWRQE-------PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSE---AEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEK-----NRLPSVHPHHSMLY 513 HSP 2 Score: 88.1965 bits (217), Expect = 5.278e-17 Identity = 98/425 (23.06%), Postives = 173/425 (40.71%), Query Frame = 2
Query: 3119 NCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPI---AYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+C ++ EP L + ++ + + T AIK + A+ N + E+ ++AI+ Y L + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP Y N + + A + YN A+ + CP + N + +E+A++ +RK +E P A NLA V Q KL+E++ + +I +SP A Y N N L ++Q Q A + ++I P +G+ A+ Y+T++
Sbjct: 43 HCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYK-ERGQLQEAIEHYRHALRLKPDF---IDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRL----CPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 456 HSP 3 Score: 77.0258 bits (188), Expect = 1.663e-13 Identity = 91/418 (21.77%), Postives = 178/418 (42.58%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI------SH-NLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
AI+ +P +EAYS +Y++ G+ + A+E Y +RL+P+ Y+N+ +AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A + N A+ L P ++ + G +E A R+A E+ +H NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 81 AIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 472 HSP 4 Score: 56.225 bits (134), Expect = 3.670e-7 Identity = 83/448 (18.53%), Postives = 173/448 (38.62%), Query Frame = 2
Query: 1835 QNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYR---GILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAY 3166
Q+G+ A Q+ R +P+N ++ + + +A + ++ P EA+ + G Y + Q Q+A+ + + L P+ Y L A + ++ + + + N Y R G L + EA + I + A NLG ++ +G+ ++ + + DP ++ AY + ++ A+ RA+ L P+ + + Y G +++A R+A E+ + + A + +A + A R P+ A LN L + + ++A+ + LE P A + +A + +++ + + ++I+P A+AY + G + ++ + RA+ INP A+ A++ +AI + L ++P AY
Sbjct: 33 QSGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAA----GDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVF----------PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 466 HSP 5 Score: 53.9138 bits (128), Expect = 1.726e-6 Identity = 80/377 (21.22%), Postives = 140/377 (37.14%), Query Frame = 2
Query: 1484 RPN-AFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL--AAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM----NKYEDAIKDI----------NRAIHLFPDRSNFYMLRGDFYLAMGK 2563
+PN A S G ++ G + A A++++P+ + AY + A+ L N+ + + + A +Y G I LAI +AI L P +AY A ++ G A E YN +RL P + ++ + L + EQ + A + + L +P A + + + + Q+AL + I + P AY G L++ ++D +G L T+ I N AH NL I+ + G+ +++ + L P + AY C Q+ Y++ +K + NR + P S Y L F A+ +
Sbjct: 187 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSL--NNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKE------MQDV------------------QGALQCYTR-----------AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY-CNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAE 525
BLAST of TPR_REGION domain-containing protein vs. Ensembl Zebrafish
Match: ogt.1 (O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9631]) HSP 1 Score: 98.2117 bits (243), Expect = 5.600e-20 Identity = 122/536 (22.76%), Postives = 218/536 (40.67%), Query Frame = 2
Query: 2669 DQAIDALLVATRGKPSVALLNLLGTTQMKAKRWK--DAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
D A VA +P+ +L+ G ++ + ++ D + C++ + + P + L++ + + + +S + +K NP AEAY + G G++++ I AL + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + + + A + YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I ++LE+ NR S+ P+ + LY
Sbjct: 57 DMASSVGNVADSTEPTKRVLSFQGLAELAHREYQSGDFEAAERHCMQLWRQE-------PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSE---AEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEK-----NRLPSVHPHHSMLY 570 HSP 2 Score: 88.1965 bits (217), Expect = 6.540e-17 Identity = 98/425 (23.06%), Postives = 173/425 (40.71%), Query Frame = 2
Query: 3119 NCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPI---AYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+C ++ EP L + ++ + + T AIK + A+ N + E+ ++AI+ Y L + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP Y N + + A + YN A+ + CP + N + +E+A++ +RK +E P A NLA V Q KL+E++ + +I +SP A Y N N L ++Q Q A + ++I P +G+ A+ Y+T++
Sbjct: 100 HCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYK-ERGQLQEAIEHYRHALRLKPDF---IDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRL----CPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 513 HSP 3 Score: 76.6406 bits (187), Expect = 2.062e-13 Identity = 90/418 (21.53%), Postives = 176/418 (42.11%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
AI+ +P +EAYS +Y++ G+ + A+E Y +RL+P+ Y+N+ +AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A + N A+ L P ++ + G +E A R+A E+ NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 138 AIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 529 HSP 4 Score: 58.5362 bits (140), Expect = 6.711e-8 Identity = 94/492 (19.11%), Postives = 191/492 (38.82%), Query Frame = 2
Query: 1733 STGDISLAISNLSQAIRLSPDDSEAYSKR-------AELYE---QNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYR---GILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAY 3166
S GD++ ++ N++ DS +KR AEL Q+G+ A Q+ R +P+N ++ + + +A + ++ P EA+ + G Y + Q Q+A+ + + L P+ Y L A + ++ + + + N Y R G L + EA + I + A NLG ++ +G+ ++ + + DP ++ AY + ++ A+ RA+ L P+ + + Y G +++A R+A E+ + + A + +A + A R P+ A LN L + + ++A+ + LE P A + +A + +++ + + ++I+P A+AY + G + ++ + RA+ INP A+ A++ +AI + L ++P AY
Sbjct: 54 SEGDMASSVGNVA--------DSTEPTKRVLSFQGLAELAHREYQSGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAA----GDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVF----------PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 523 HSP 5 Score: 53.9138 bits (128), Expect = 1.862e-6 Identity = 80/377 (21.22%), Postives = 140/377 (37.14%), Query Frame = 2
Query: 1484 RPN-AFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL--AAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM----NKYEDAIKDI----------NRAIHLFPDRSNFYMLRGDFYLAMGK 2563
+PN A S G ++ G + A A++++P+ + AY + A+ L N+ + + + A +Y G I LAI +AI L P +AY A ++ G A E YN +RL P + ++ + L + EQ + A + + L +P A + + + + Q+AL + I + P AY G L++ ++D +G L T+ I N AH NL I+ + G+ +++ + L P + AY C Q+ Y++ +K + NR + P S Y L F A+ +
Sbjct: 244 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSL--NNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKE------MQDV------------------QGALQCYTR-----------AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY-CNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAE 582
BLAST of TPR_REGION domain-containing protein vs. Ensembl Zebrafish
Match: ogt.1 (O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9631]) HSP 1 Score: 97.8265 bits (242), Expect = 6.986e-20 Identity = 120/528 (22.73%), Postives = 216/528 (40.91%), Query Frame = 2
Query: 2693 VATRGKPSVALLNLLGTTQMKAKRWK--DAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
VA +P+ +L+ G ++ + ++ D + C++ + + P + L++ + + + +S + +K NP AEAY + G G++++ I AL + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + + + A + YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I ++LE+ NR S+ P+ + LY
Sbjct: 8 VADSTEPTKRVLSFQGLAELAHREYQSGDFEAAERHCMQLWRQE-------PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSE---AEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEK-----NRLPSVHPHHSMLY 513 HSP 2 Score: 87.8113 bits (216), Expect = 8.067e-17 Identity = 98/425 (23.06%), Postives = 173/425 (40.71%), Query Frame = 2
Query: 3119 NCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPI---AYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+C ++ EP L + ++ + + T AIK + A+ N + E+ ++AI+ Y L + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP Y N + + A + YN A+ + CP + N + +E+A++ +RK +E P A NLA V Q KL+E++ + +I +SP A Y N N L ++Q Q A + ++I P +G+ A+ Y+T++
Sbjct: 43 HCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYK-ERGQLQEAIEHYRHALRLKPDF---IDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRL----CPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 456 HSP 3 Score: 76.6406 bits (187), Expect = 2.105e-13 Identity = 91/418 (21.77%), Postives = 178/418 (42.58%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI------SH-NLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
AI+ +P +EAYS +Y++ G+ + A+E Y +RL+P+ Y+N+ +AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A + N A+ L P ++ + G +E A R+A E+ +H NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 81 AIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 472 HSP 4 Score: 55.8398 bits (133), Expect = 5.302e-7 Identity = 83/448 (18.53%), Postives = 173/448 (38.62%), Query Frame = 2
Query: 1835 QNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYR---GILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAY 3166
Q+G+ A Q+ R +P+N ++ + + +A + ++ P EA+ + G Y + Q Q+A+ + + L P+ Y L A + ++ + + + N Y R G L + EA + I + A NLG ++ +G+ ++ + + DP ++ AY + ++ A+ RA+ L P+ + + Y G +++A R+A E+ + + A + +A + A R P+ A LN L + + ++A+ + LE P A + +A + +++ + + ++I+P A+AY + G + ++ + RA+ INP A+ A++ +AI + L ++P AY
Sbjct: 33 QSGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAA----GDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVF----------PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 466 HSP 5 Score: 53.5286 bits (127), Expect = 2.215e-6 Identity = 80/377 (21.22%), Postives = 140/377 (37.14%), Query Frame = 2
Query: 1484 RPN-AFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL--AAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM----NKYEDAIKDI----------NRAIHLFPDRSNFYMLRGDFYLAMGK 2563
+PN A S G ++ G + A A++++P+ + AY + A+ L N+ + + + A +Y G I LAI +AI L P +AY A ++ G A E YN +RL P + ++ + L + EQ + A + + L +P A + + + + Q+AL + I + P AY G L++ ++D +G L T+ I N AH NL I+ + G+ +++ + L P + AY C Q+ Y++ +K + NR + P S Y L F A+ +
Sbjct: 187 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSL--NNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKE------MQDV------------------QGALQCYTR-----------AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY-CNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAE 525
BLAST of TPR_REGION domain-containing protein vs. Ensembl Xenopus
Match: tbx2 (T-box 2 [Source:Xenbase;Acc:XB-GENE-1018115]) HSP 1 Score: 340.502 bits (872), Expect = 1.490e-97 Identity = 283/1005 (28.16%), Postives = 473/1005 (47.06%), Query Frame = 2
Query: 1163 KNRGYKKESNARDWITVIWDQWFDEIYPPIPDHIIDLTSDKPSETPYKNELLNREPTSVSAIQNEILDLPENIEPVLDEVDEEFRGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAW-LHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLI-YFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM-------------------------------------------NKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEM-AAICV---RQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKP-SVALLNLLGTTQ--MKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGA---ANLNFLVAR--CYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATL---FGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSL---AIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKD-YNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGG 3985
K G + + R+W+ IW+ WFDE++PP +SD E PY + + + A + IL L ++++PVL E GA E L E+ ++ ++ ++P AF RRGAL RK+G L A +D+N AI++EP L+ AYW RHL+ + K A+EDLN+I+K +K Y AY S+A IY GD +++I + +QA++ PDD E Y +RA++YE E ++A++DY + +L + A+ KHG+Y W +A +DF+++++ +N EA + RG A+ +L + +A DFSA IHL+P+N++A++ RGCLLRK P+ A++DF + L S EN+ +++YRGILY ++EAI DFE V+ ++ + AH+NLGLI + D+ +++++ T+ L DP YI+AY CRA+A+ Q+ N ++ A++ + AI + Y RG + +M + A C+ +A EI+ N Q+ + +A + F + Y +AI A + +P SV G + +K +R I S C+ + K+ G + LV R YLEL+++ + T K EA + N+AL I P +A + R +G + +A + L + P C+ A R L Y ++A L A FT A+ ID IL F RA+ + + + A+QD + L + + L NRG+++ +G + NA+ D+ A + D + LA + N+++ N + AK+ Y + +D + A++N G + A F + + P S RA + + A D+++A+ +QP ++Y R + + A++DY AI + G
Sbjct: 123 KYGGIRDKQVVREWVRDIWNTWFDEVFPPS-----RASSDNEQEQPY-----SLKEITEGATKEGILWLQDSVQPVLIEDP----GASVEDLEGEIARLTVLIDEKEKPCAFHCCRRGALNRKLGKLSLAIQDLNLAINLEPQLLDAYWNRHLIFCLQGKTTAALEDLNMIIKLNKLYTDAYLSKAEIYKQEGDYTMSILSYTQALKCRPDDDEIYFRRAQMYEAQDEYKIAMDDYAKCFQLSQSRVDALQKHGMYCFENCNWNIAVQDFTALIKQDINNVEASRIFRGRAHTQLANYTEAAEDFSAAIHLNPSNWMAFYYRGCLLRKCLPWQAVQDFML---LCDSSENLNAFLYRGILYIDMGLWAEAICDFERVLALDRTVVLAHMNLGLISLLNRKDYAQAIRHFTAALNVDPVYIKAYLCRAQAFQQVHICYCLSALIFFFICIPLDIFLLKFHVVDPYSFCTLVPASYSYNTFQ-ALEALTSAIKVRSRFHEAYYQRG-----LCRMHLQQAKCLDDFNKALEINPNYFQALLCRATFYGFRKRYSKAIMNCNAAIKVQPHSVRAYLYRGALKYYIKVRR----ILSLIVCIYRGALKDYSIVLLLGGWKEVDSKVLVNRGLLYLELQDFANALEVSMCTQKFRQQFFEA-----------------VQAFNQALNITPLSAEACIGRGNAYIEYGHQRGTAQAKRDFLRALHLSPSCVAA---RICLGYTLQAQGLFQQAWNHFTVALDIDPQSILGFEGRAI-VSLQIGDTFAALQDMNAALKLCGSAQL----LTNRGVIHQFMGKLPNAMRDYQAA----------------------------------ITADQDYSLAYFNAANLYL----HNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQYQWAESDISQALNLQPDDPLIYKLRADIRGKLGLTKEAIEDYEHAITLLG 1037 HSP 2 Score: 317.005 bits (811), Expect = 1.289e-89 Identity = 272/956 (28.45%), Postives = 421/956 (44.04%), Query Frame = 2
Query: 1670 LILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPY-LAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPC-RAEAYFQMNKYEDAIKDINRAIHLFP-----------------------------DRS---NFYMLRGDFYLAMGKMEMAAIC-VRQAAEISHNLGQSPVQQALVHSFL--QHYDQAIDALLVATRGKP---SVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLV----ARCYLELKNYKKSQL----AFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKN-LKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
LI +K+K R + G +SLAI +L+ AI L P +AY R ++ G+ ALED N II+L + LY T+A+L + Y + + ++ ++ + P++ YF+R + + Y +A+ D YA Q S++ VD A G+ FE ++ +V+ T+ + D + A R A+ Q+ Y +A +D + AIHL P D S N ++ RG Y+ MG + AIC + + + + + L+ S L + Y QAI A P L Q+ A+ F C+ P L F V + C L +Y + A ++ +K+ EAYY +G CR+ L + K + D N+AL INP +QA L RAT +GF+ +Y+KAI+NCN + ++P +RAYLYRG LKY IK + + VC Y A++DYSIVLL+ + K +NRGL+YLEL D NAL V +C K + EA++ F + L+ P A + RGN +++Y A +D+ L + + A + LG+ QAQG F++AW+ FT+A++ P S +GRAIV +Q+ D AL+D+N A+++ S+ L NRGV++Q M AM+DY +A I +AYFNA +Y+HN Q QA E + + V DP +E+ +N + + + ++ +SL P S+ YFNRA++ LQ+YQ AE D L + PDDP + K R D R K G + A+EDY+ ++ +
Sbjct: 210 LIDEKEKPCAFHCCRRGALNRKLGKLSLAIQDLNLAINLEPQLLDAYWNRHLIFCLQGKTTAALEDLNMIIKL----------NKLY------------------------TDAYLSKAEIYKQEGDYTMSILSYTQALKCRPDDDEIYFRRAQMYEAQDEYKIAMDD-----------------------YAKCFQLSQSRVD-------------ALQKHGMYCFENCNWNIAVQDFTALIKQDINNVEASRIFRGRAHTQLANYTEAAEDFSAAIHLNPSNWMAFYYRGCLLRKCLPWQAVQDFMLLCDSSENLNAFLYRGILYIDMG-LWAEAICDFERVLALDRTVVLAHMNLGLI-SLLNRKDYAQAIRHFTAALNVDPVYIKAYLCRAQAFQQVHICYCLSALIFFFICI------------PLDIFLLKFHVVDPYSFCTLVPASYSYNTFQALEALTSAIKVRSRFHEAYYQRGLCRMHLQQAK-CLDDFNKALEINPNYFQALLCRATFYGFRKRYSKAIMNCNAAIKVQPHSVRAYLYRGALKYYIK-------------------VRRILSLIVCI------YRGALKDYSIVLLLGGWKEVDSKVLVNRGLLYLELQDFANALE------------------VSMCTQKFRQQFFEAVQAFNQALNITPLSAEACIGRGNAYIEYGHQRGTAQAKRDFLRALHLSPSCVAARICLGYTLQAQGLFQQAWNHFTVALDIDPQSILGFEGRAIVSLQIGDTFAALQDMNAALKL-CGSAQLLTNRGVIHQFMGKLPNAMRDY-QAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQYQWAESDISQALNLQPDDPLIYKLRADIRGKLGLTKEAIEDYEHAITL 1035
BLAST of TPR_REGION domain-containing protein vs. Ensembl Xenopus
Match: tbx2 (T-box 2 [Source:Xenbase;Acc:XB-GENE-1018115]) HSP 1 Score: 294.278 bits (752), Expect = 1.091e-86 Identity = 175/491 (35.64%), Postives = 262/491 (53.36%), Query Frame = 2
Query: 2915 AFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLK-NLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
A ++ +K+ EAYY +G CR+ L + K + D N+AL INP +QA L RAT +GF+ +Y+KAI+NCN + ++P +RAYLYRG LKY IK + + VC Y A++DYSIVLL+ + K +NRGL+YLEL D NAL V +C K + EA++ F + L+ P A + RGN +++Y A +D+ L + + A + LG+ QAQG F++AW+ FT+A++ P S +GRAIV +Q+ D AL+D+N A+++ S+ L NRGV++Q M AM+DY +A I +AYFNA +Y+HN Q QA E + + V DP +E+ +N + + + ++ +SL P S+ YFNRA++ LQ+YQ AE D L + PDDP + K R D R K G + A+EDY+ ++
Sbjct: 58 ALTSAIKVRSRFHEAYYQRGLCRMHLQQAK-CLDDFNKALEINPNYFQALLCRATFYGFRKRYSKAIMNCNAAIKVQPHSVRAYLYRGALKYYIK-------------------VRRILSLIVCI------YRGALKDYSIVLLLGGWKEVDSKVLVNRGLLYLELQDFANALE------------------VSMCTQKFRQQFFEAVQAFNQALNITPLSAEACIGRGNAYIEYGHQRGTAQAKRDFLRALHLSPSCVAARICLGYTLQAQGLFQQAWNHFTVALDIDPQSILGFEGRAIVSLQIGDTFAALQDMNAALKL-CGSAQLLTNRGVIHQFMGKLPNAMRDY-QAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQYQWAESDISQALNLQPDDPLIYKLRADIRGKLGLTKEAIEDYEHAI 502 HSP 2 Score: 75.485 bits (184), Expect = 3.955e-13 Identity = 59/205 (28.78%), Postives = 95/205 (46.34%), Query Frame = 2
Query: 1514 GALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRG 2128
G + G A A+ I+P I+ + R ++ L A++D+N LK + L +R I+ G + A+ + AI D S AY A LY N + A E Y + + L P N A++ G+ + ++ Q A DF VL P ++ A+ +R + Y LQQ+Q A +D S ++L P++ L Y R
Sbjct: 279 GYTLQAQGLFQQAWNHFTVALDIDPQSILGFEGRAIVSLQIGDTFAALQDMNAALKLCGSAQL-LTNRGVIHQFMGKLPNAMRDYQAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQYQWAESDISQALNLQPDDPLIYKLRA 482 HSP 3 Score: 69.707 bits (169), Expect = 2.496e-11 Identity = 107/479 (22.34%), Postives = 184/479 (38.41%), Query Frame = 2
Query: 1550 ASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRL----------ALEDYNQIIRL---QPNNCLAMMKHGLYYLNI-----------------EQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAK----------------------------------LQQ---WQDALTDFSAVIHLDPNNYLAYFKRGCL-LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAIT 2782
A + + AI + AY++R L + + + ++D N L+ + NY A RA Y S AI N + AI++ P AY R L R+ AL+DY+ ++ L + + ++ GL YL + +Q+ A + F+ L P + EA + RG AY + LQ +Q A F+ + +DP + L + R + L+ + + A++D + +L L S + + + RG+++ + A+ D++ I ++D A+ N +Y F ++ +Y T +A DP A R + + A+ D + L P S Y R Y + + + A +S + QAL LQ D I L RGK LG T+ + ++ AIT
Sbjct: 55 ALEALTSAIKVRSRFHEAYYQRGLCRMHLQQAK-CLDDFNKALEINPNYFQALLCRATFYGFRKRYSKAIMNCNAAIKVQPHSVRAYLYRGALKYYIKVRRILSLIVCIYRGALKDYSIVLLLGGWKEVDSKVLVNRGLLYLELQDFANALEVSMCTQKFRQQFFEAVQAFNQALNITPLSAEACIGRGNAYIEYGHQRGTAQAKRDFLRALHLSPSCVAARICLGYTLQAQGLFQQAWNHFTVALDIDPQSILGFEGRAIVSLQIGDTFAALQDMNAALKLCGSAQLLTN---RGVIHQFMGKLPNAMRDYQAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQYQWA---------------ESDISQALN---LQPDDPLIYKLRADIRGK--------LGLTKEAIEDYEHAIT 503 HSP 4 Score: 62.7734 bits (151), Expect = 3.065e-9 Identity = 55/218 (25.23%), Postives = 92/218 (42.20%), Query Frame = 2
Query: 1511 RGALYRKMGY---LVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPY 2155
RG Y + G+ A +D A+ + P + A Q A + L D +L ++ RA + GD A+ +++ A++L ++ + R +++ G+ A+ DY I + LA YL+ Q+ A + ++ + P+N A L+RG LQ Q AL DF V+ L P + AYF R L + Y
Sbjct: 241 RGNAYIEYGHQRGTAQAKRDFLRALHLSPSCVAARICLGYTLQAQGLFQQAWNHFTVALDIDPQSILGFEGRAIVSLQIGDTFAALQDMNAALKLC-GSAQLLTNRGVIHQFMGKLPNAMRDYQAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQY 457 HSP 5 Score: 61.2326 bits (147), Expect = 9.476e-9 Identity = 84/364 (23.08%), Postives = 151/364 (41.48%), Query Frame = 2
Query: 2390 GLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRG--DFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVAL------LNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLA---FSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLY--RGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDF 3442
L +P Y +A CRA Y +Y AI + N AI + P Y+ RG +Y+ + ++ +C+ + A +++ L + +D+ ++ RG + L L + TQ +++ +A+ +F NQ P +A Y+E + + + A F + ++P+ A G+ G +Q AL I+P+ + RA + A+ + N L + C A L RGV+ + A++D+ AI D + LA+FN A + + + +A + Y+ + + A + A +NRG+ + L D Q ALHDF
Sbjct: 95 ALEINPNYFQALLCRATFYGFRKRYSKAIMNCNAAIKVQPHSVRAYLYRGALKYYIKVRRILSLIVCIYRGALKDYSI-----------VLLLGGWKEVDSKVLVNRGLLYLELQDFANALEVSMCTQKFRQQFFEAVQAF----------NQALNITPLSAEACIGRGNAYIEYGHQRGTAQAKRDFLRALHLSPSCVAARICLGYTLQAQGLFQQAWNHFTVALDIDPQSILGFEGRAIVSLQIGDTFAALQDMNAALKL---CGSAQLLTNRGVIHQFMGKLPNAMRDYQAAITADQDYSLAYFNAANLY-LHNRQFTQAKEYYTRAVALDPA---NESAVLNRGITNMLLQDAQAALHDF 430 HSP 6 Score: 56.225 bits (134), Expect = 3.455e-7 Identity = 45/167 (26.95%), Postives = 72/167 (43.11%), Query Frame = 2
Query: 1490 NAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWE----------------------------------RHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRL 1888
+A LL+ RG +++ MG L A +D AI+ + D +AY+ R + +++ Q A+ D L+L AY +RA +Y + A S++SQA+ L PDD Y RA++ + G + A+EDY I L
Sbjct: 338 SAQLLTNRGVIHQFMGKLPNAMRDYQAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQYQWAESDISQALNLQPDDPLIYKLRADIRGKLGLTKEAIEDYEHAITL 504
BLAST of TPR_REGION domain-containing protein vs. Ensembl Xenopus
Match: tbx2 (T-box 2 [Source:Xenbase;Acc:XB-GENE-1018115]) HSP 1 Score: 241.891 bits (616), Expect = 3.111e-70 Identity = 133/361 (36.84%), Postives = 206/361 (57.06%), Query Frame = 2
Query: 3308 YEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
Y++A++DYSIVLL+ + K +NRGL+YLEL D NAL DF P D+ + V+G CH +L+ +EA++ F + L+ P A + RGN +++Y A +D+ L + + A + LG+ QAQG F++AW+ FT+A++ P S +GRAIV +Q+ D AL+D+N A+++ S+ L NRGV++Q M AM+DY +A I +AYFNA +Y+HN Q QA E + + V DP +E+ +N + + + ++ +SL P S+ YFNRA++ LQ+YQ AE D L + PDDP + K R D R K G + A+EDY+ ++ +
Sbjct: 2 YDEALKDYSIVLLLGGWKEVDSKVLVNRGLLYLELQDFANALEDFKCVALRTPGDIKIHLVIGNCHQRLQQYEEAVQAFNQALNITPLSAEACIGRGNAYIEYGHQRGTAQAKRDFLRALHLSPSCVAARICLGYTLQAQGLFQQAWNHFTVALDIDPQSILGFEGRAIVSLQIGDTFAALQDMNAALKL-CGSAQLLTNRGVIHQFMGKLPNAMRDY-QAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQYQWAESDISQALNLQPDDPLIYKLRADIRGKLGLTKEAIEDYEHAITL 360 HSP 2 Score: 74.7146 bits (182), Expect = 3.311e-13 Identity = 56/186 (30.11%), Postives = 91/186 (48.92%), Query Frame = 2
Query: 1571 AISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRG 2128
A+ I+P I+ + R ++ L A++D+N LK + L +R I+ G + A+ + AI D S AY A LY N + A E Y + + L P N A++ G+ + ++ Q A DF VL P ++ A+ +R + Y LQQ+Q A +D S ++L P++ L Y R
Sbjct: 154 ALDIDPQSILGFEGRAIVSLQIGDTFAALQDMNAALKLCGSAQL-LTNRGVIHQFMGKLPNAMRDYQAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQYQWAESDISQALNLQPDDPLIYKLRA 338 HSP 3 Score: 65.855 bits (159), Expect = 1.976e-10 Identity = 78/361 (21.61%), Postives = 151/361 (41.83%), Query Frame = 2
Query: 2258 FSEAIVDFEVVICFN--KDM-CFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVR---QAAEISHN-------LGQSPVQQALVHSFLQHYDQAID---ALLVATRGKPSVAL---------------LNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFL-VARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKI 3244
+ EA+ D+ +V+ K++ VN GL+Y E DF +++ P I+ + + ++ +YE+A++ N+A+++ P + + RG+ Y+ G A R +A +S + LG + Q L H+ A+D ++ G+ V+L L L G+ Q+ R I F L Q +L + A YL + + +++ ++ V ++P + A ++G + L + + D L++ P AY RA+L+ QY A + ++ L+++P Y R ++ K+ AI+D+ AI +
Sbjct: 2 YDEALKDYSIVLLLGGWKEVDSKVLVNRGLLYLELQDFANALEDFKCVALRTPGDIKIHLVIGNCHQRLQQYEEAVQAFNQALNITPLSAEACIGRGNAYIEYGHQRGTAQAKRDFLRALHLSPSCVAARICLGYTLQAQGLFQQAWNHFTVALDIDPQSILGFEGRAIVSLQIGDTFAALQDMNAALKLCGSAQLLTNR--GVIHQFMGKLPNAMRDYQAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQYQWAESDISQALNLQPDDPLIYKLRADIRGKLGLTKEAIEDYEHAITL 360 HSP 4 Score: 62.7734 bits (151), Expect = 1.820e-9 Identity = 62/299 (20.74%), Postives = 125/299 (41.81%), Query Frame = 2
Query: 1712 SRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAA---KDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCL-LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQA 2596
+R +Y D + A+ + +P D + + +++ + A++ +NQ + + P + A + G Y+ + A +DF L PS A + G +Q A F+ + +DP + L + R + L+ + + A++D + +L L S + + + RG+++ + A+ D++ I ++D A+ N +Y F ++ +Y T +A DP A R + + A+ D + L P S Y R Y + + + A + QA
Sbjct: 28 NRGLLYLELQDFANALEDFKCVALRTPGDIKIHLVIGNCHQRLQQYEEAVQAFNQALNITPLSAEACIGRGNAYIEYGHQRGTAQAKRDFLRALHLSPSCVAARICLGYTLQAQGLFQQAWNHFTVALDIDPQSILGFEGRAIVSLQIGDTFAALQDMNAALKLCGSAQLLTN---RGVIHQFMGKLPNAMRDYQAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQYQWAESDISQA 323 HSP 5 Score: 61.6178 bits (148), Expect = 4.413e-9 Identity = 55/218 (25.23%), Postives = 92/218 (42.20%), Query Frame = 2
Query: 1511 RGALYRKMGY---LVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPY 2155
RG Y + G+ A +D A+ + P + A Q A + L D +L ++ RA + GD A+ +++ A++L ++ + R +++ G+ A+ DY I + LA YL+ Q+ A + ++ + P+N A L+RG LQ Q AL DF V+ L P + AYF R L + Y
Sbjct: 97 RGNAYIEYGHQRGTAQAKRDFLRALHLSPSCVAARICLGYTLQAQGLFQQAWNHFTVALDIDPQSILGFEGRAIVSLQIGDTFAALQDMNAALKLC-GSAQLLTNRGVIHQFMGKLPNAMRDYQAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQY 313 HSP 6 Score: 61.2326 bits (147), Expect = 6.399e-9 Identity = 86/400 (21.50%), Postives = 158/400 (39.50%), Query Frame = 2
Query: 1856 ALEDYNQIIRL---QPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPS--VALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAI 3040
AL+DY+ ++ L + + ++ GL YL ++ + A +DF V P + + L G + +LQQ+++A+ F+ +++ P + A RG Y I Y + ++A DF + + A + LG +G F+++ + T L DP I + RA Q+ A++D+N A+ L + RG + MGK+ A + A + + A ++ + + QA + A P+ A+LN G T M + + A+ F L P ++ F A Y L+ Y+ ++ S + + P+ Y + R +LG K+ I D A+ +
Sbjct: 5 ALKDYSIVLLLGGWKEVDSKVLVNRGLLYLELQDFANALEDFKCVALRTPGDIKIHLVIGNCHQRLQQYEEAVQAFNQALNITPLSAEACIGRG------NAY--------------------------IEYGHQRGTAQAKRDFLRALHLSPSCVAARICLGYTLQAQGLFQQAWNHFTVALDIDPQSILGFEGRAIVSLQIGDTFAALQDMNAALKLCGS-AQLLTNRGVIHQFMGKLPNAMRDYQAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLN-RGITNMLLQDAQAALHDFQLVLS----------LCPVSSAAYFNRASLYNTLQQYQWAESDISQALNLQPDDPLIYKLRADIRGKLGLTKEAIEDYEHAITL 360 HSP 7 Score: 55.4546 bits (132), Expect = 3.817e-7 Identity = 45/167 (26.95%), Postives = 72/167 (43.11%), Query Frame = 2
Query: 1490 NAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWE----------------------------------RHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRL 1888
+A LL+ RG +++ MG L A +D AI+ + D +AY+ R + +++ Q A+ D L+L AY +RA +Y + A S++SQA+ L PDD Y RA++ + G + A+EDY I L
Sbjct: 194 SAQLLTNRGVIHQFMGKLPNAMRDYQAAITADQDYSLAYFNAANLYLHNRQFTQAKEYYTRAVALDPANESAVLNRGITNMLLQDAQAALHDFQLVLSLCPVSSAAYFNRASLYNTLQQYQWAESDISQALNLQPDDPLIYKLRADIRGKLGLTKEAIEDYEHAITL 360
BLAST of TPR_REGION domain-containing protein vs. Ensembl Xenopus
Match: eno4 (enolase 4 [Source:Xenbase;Acc:XB-GENE-1009720]) HSP 1 Score: 101.679 bits (252), Expect = 6.119e-21 Identity = 137/591 (23.18%), Postives = 240/591 (40.61%), Query Frame = 2
Query: 2693 VATRGKPSVALLNLLGTTQMKAKRWK--DAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY-----FNRANVLFDLQRYQEAELDFCSCLRIAP-DDPHVLKARGDCRSKTGDSLGALEDYKTS 4381
+ + GKP+ +L+ G ++ + ++ D + C++ + + P + L++ + + + +S + +K NP AEAY + G G++++ I AL + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + S A + YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I ++LE+ NR S+ P+ + LY F +A +R+ LD + L P + P LKA D R + G ++ TS
Sbjct: 7 IGSIGKPTKRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQE-------PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVVD---AEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEK-----NRLPSVHPHHSMLYPLSHGFRKAIA----ERHGNLCLDKINVLHKPPYEHPKDLKA-SDGRLRVGYVSSDFGNHPTS 570 HSP 2 Score: 89.7373 bits (221), Expect = 3.057e-17 Identity = 106/468 (22.65%), Postives = 185/468 (39.53%), Query Frame = 2
Query: 2990 LGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPI---AYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+GK + +L + R YQA + A +C ++ EP L + ++ + + T AIK + A+ N + E+ ++AI+ Y L + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP Y N + + A + YN A+ + CP + N + +E+A+ +RK +E P A NLA V Q KL+E++ + +I +SP A Y N N L ++Q Q A + ++I P +G+ A+ Y+T++
Sbjct: 10 IGKPTKRMLSFQGLAELAHREYQA-----------GDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYK-ERGQLQEAIEHYRHALRLKPDF---IDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVVDAEECYNTALRL----CPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 455 HSP 3 Score: 77.7962 bits (190), Expect = 1.233e-13 Identity = 91/418 (21.77%), Postives = 176/418 (42.11%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
AI+ +P +EAYS +Y++ G+ + A+E Y +RL+P+ Y+N+ +AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + DA + N A+ L P ++ + G +E A R+A E+ NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 80 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVVDAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 471 HSP 4 Score: 52.7582 bits (125), Expect = 5.633e-6 Identity = 79/377 (20.95%), Postives = 138/377 (36.60%), Query Frame = 2
Query: 1484 RPN-AFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL--AAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM----NKYEDAIKDI----------NRAIHLFPDRSNFYMLRGDFYLAMGK 2563
+PN A S G ++ G + A A++++P+ + AY + A+ L N+ + + + A +Y G I LAI +AI L P +AY A ++ G A E YN +RL P + ++ + L + EQ + A + + L +P A + + + + Q+AL + I + P AY G L++ + +G L T+ I N AH NL I+ + G+ +++ + L P + AY C Q+ Y++ +K + NR + P S Y L F A+ +
Sbjct: 186 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVVDAEECYNTALRLCPTHADSL--NNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQD------------------------VQGALQCYTR-----------AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY-CNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAE 524
BLAST of TPR_REGION domain-containing protein vs. Ensembl Xenopus
Match: eno4 (enolase 4 [Source:Xenbase;Acc:XB-GENE-1009720]) HSP 1 Score: 98.5969 bits (244), Expect = 4.991e-20 Identity = 137/592 (23.14%), Postives = 239/592 (40.37%), Query Frame = 2
Query: 2690 LVATRGKPSVALLNLLGTTQMKAKRWK--DAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY-----FNRANVLFDLQRYQEAELDFCSCLRIAP-DDPHVLKARGDCRSKTGDSLGALEDYKTS 4381
L+ KP+ +L+ G ++ + ++ D + C++ + + P + L++ + + + +S + +K NP AEAY + G G++++ I AL + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + S A + YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I ++LE+ NR S+ P+ + LY F +A +R+ LD + L P + P LKA D R + G ++ TS
Sbjct: 35 LLRNSTKPTKRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQE-------PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVVD---AEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEK-----NRLPSVHPHHSMLYPLSHGFRKAIA----ERHGNLCLDKINVLHKPPYEHPKDLKA-SDGRLRVGYVSSDFGNHPTS 599 HSP 2 Score: 88.9669 bits (219), Expect = 5.203e-17 Identity = 98/425 (23.06%), Postives = 172/425 (40.47%), Query Frame = 2
Query: 3119 NCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPI---AYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+C ++ EP L + ++ + + T AIK + A+ N + E+ ++AI+ Y L + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP Y N + + A + YN A+ + CP + N + +E+A+ +RK +E P A NLA V Q KL+E++ + +I +SP A Y N N L ++Q Q A + ++I P +G+ A+ Y+T++
Sbjct: 71 HCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYK-ERGQLQEAIEHYRHALRLKPDF---IDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVVDAEECYNTALRL----CPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 484 HSP 3 Score: 77.7962 bits (190), Expect = 1.334e-13 Identity = 91/418 (21.77%), Postives = 176/418 (42.11%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
AI+ +P +EAYS +Y++ G+ + A+E Y +RL+P+ Y+N+ +AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + DA + N A+ L P ++ + G +E A R+A E+ NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 109 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVVDAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 500 HSP 4 Score: 52.7582 bits (125), Expect = 5.078e-6 Identity = 79/377 (20.95%), Postives = 138/377 (36.60%), Query Frame = 2
Query: 1484 RPN-AFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL--AAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM----NKYEDAIKDI----------NRAIHLFPDRSNFYMLRGDFYLAMGK 2563
+PN A S G ++ G + A A++++P+ + AY + A+ L N+ + + + A +Y G I LAI +AI L P +AY A ++ G A E YN +RL P + ++ + L + EQ + A + + L +P A + + + + Q+AL + I + P AY G L++ + +G L T+ I N AH NL I+ + G+ +++ + L P + AY C Q+ Y++ +K + NR + P S Y L F A+ +
Sbjct: 215 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVVDAEECYNTALRLCPTHADSL--NNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQD------------------------VQGALQCYTR-----------AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY-CNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAE 553
BLAST of TPR_REGION domain-containing protein vs. Ensembl Mouse
Match: Ttc6 (tetratricopeptide repeat domain 6 [Source:MGI Symbol;Acc:MGI:2684915]) HSP 1 Score: 698.353 bits (1801), Expect = 0.000e+0 Identity = 399/1092 (36.54%), Postives = 638/1092 (58.42%), Query Frame = 2
Query: 1139 IHNFEDWSKNRGYKKESNARDWITVIWDQWFDEIYPPIPDHIIDLTSDKPSETPYKNELLNREPTSVSAIQNEILDLPENIEPVLD----EVDEEFRGALFETLLE----EVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGD-FEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQ-SPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
I NF+ ++++RG N W W E++ DKP +T T+V++ E D+PE PV++ E+ + + L +++ EV+ +++++++ +R AF+ RRGA+YRK+G L +A D+ +AI EP + AYW RH ++L +K+ A++DLN I K +KN+ AY S+A I+ DI+LAI N SQAI+ P D++ Y KR E+YE+ + LA++DY++ I A+ K G++Y W A DF+S+L+ P N++A +RG AY K ++ A DFSA IHLDPNN++A + R CL RK+ PY A++D+S+S+L+ +N+ +++RGILY K + AI DFE V+ ++ A++N+G+IY E D + ++ + T + DP Y+++Y CRAE Y +++K + A+ ++ RAIHL PD + Y++RG F L M ++A + Q AE++ + + SP+Q+AL++SF +++D+AI L KP ++ LL QMKAKR K+++ F LE ++ +A + + CY+E N++ + +F+ VK NP AEA+YH+G C+++L K + ILD NRAL +NP+ YQAYL+R +G K +Y+KAILNCNE + + P +RAY+ RGVLKY + Y L I D + AIK+D N A++NRA+C+ + ++ A++DY IVLL+ ++ INRGL+Y EL AL DF +A + + + CHH++K + A+ FTR + +P ++ A + RGN +M+Y+ ++ A KD+ L +D L A ++LG+ QAQGKF+KAW FT+ IE +P S +GRA+VC+QMS+ A++D+N AI+I + L NRGV+++ M + AM DY AI + +AYFNAG +Y+H+ Q QA + F ++ +P +E +N A+ K EE+ + + ++ P+ A LYFNRA+ L++Y+ AE D L + PD+ + R R K G A+ DY ++
Sbjct: 795 ILNFDKFAESRG-GIPKNTDPWT------WVLELF----------AKDKPRQTH----------TAVASSAQE--DVPE---PVIELSKLELSDHVKCNLPPEVIKYYESEVEKLTQEIKSEKRNLAFVYCRRGAIYRKLGKLQSAMNDLQEAIFQEPFFLNAYWHRHFIYLFQDKVNDALDDLNFITKYNKNHAEAYLSKAEIFREK-DITLAILNYSQAIKCRPKDADLYFKRGEMYEKTNKV-LAIDDYSKCIYYNRKRSDALWKRGMFYFENGNWIGAVYDFTSLLKLDPYNSKARTYRGRAYFKRNLYKQATQDFSAAIHLDPNNWVALYYRACLFRKSSPYRALQDYSVSVLINDGYDNLNCFLHRGILYTQLKFWMLAICDFETVVSLERNATLAYINIGIIYLEHLDNYTEAFWWFTEAIKVDPLYLQSYICRAETYSKLHKLKRAVIELTRAIHLQPDAIHLYIMRGQFLLMMKSYDLAKFTIYQVAEMNKGIIEMSPIQEALIYSFCENHDKAIHILEGVIASKPDISTYALLAKAQMKAKRIKESVRLFKKALELYTFSDKGPVATSVSAECLYNLGLCYMEEGNFQMAFESFTKAVKANPEFAEAFYHRGLCKVKLNK-QNSILDFNRALTLNPKHYQAYLSRVAYYGLKGRYSKAILNCNEAIKLYPESVRAYICRGVLKYYNRTYKLGITDLSTAIKMDKNNYTAYYNRALCYT-KIGEHQMALRDYGIVLLLDAGENIALNTLINRGLIYTELKQYGFALEDFKQAALMSGTSVSLCQATATCHHRIKEFEGAVEFFTRAIKINPHYVDAYIGRGNSYMEYSQEDAMIQAQKDFLKALHLDPSCLKARISLGYNLQAQGKFQKAWIHFTVGIESNPKSYLAYEGRAVVCLQMSNYFAAMQDINCAIKINSTAEFL-TNRGVIHEFMGQQQSAMADYQAAISLNP-SYSLAYFNAGNIYLHHRQFSQASDYFSTALKFNPENEYALMNRAVTNSVLKKYEEAEKDFSCAMERCPHWAALYFNRASFYVYLKKYKLAEEDLGIGLSLKPDEAIMYNLRAQVRGKMGLIAEAMSDYNQAL 1848 HSP 2 Score: 79.337 bits (194), Expect = 4.548e-14 Identity = 97/438 (22.15%), Postives = 177/438 (40.41%), Query Frame = 2
Query: 1511 RGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSK---RAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDAL----TDFSAVIHLD----------------------------------PNNYLAYFKRGCL-LRKAEPYLAIRDFSIXXXXXXXXXNI-------------------------------MSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI 2605
R A Y G A + N+AI + P+ + AY R +L ++ I DL+ +K DKN AY +RA Y G+ +A+ + + L ++ A + R +Y + + ALED+ Q + + + I++++ A + F+ ++ P +A++ RG +Y + Q +DA+ DF +HLD P +YLAY R + L+ + + A++D + ++ + S+ E + ++Y G +Y +QFS+A F + FN + +A +N + +E++ K + + P + Y RA Y + KY+ A +D+ + L PD + Y LR MG + A QA ++
Sbjct: 1414 RVAYYGLKGRYSKAILNCNEAIKLYPESVRAYICRGVLKYYNRTYKLGITDLSTAIKMDKNNYTAYYNRALCYTKIGEHQMALRDYGIVLLLDAGENIALNTLINRGLIYTELKQYGFALEDFKQAALMSGTSVSLCQATATCHHRIKEFEGAVEFFTRAIKINPHYVDAYIGRGNSYMEYSQ-EDAMIQAQKDFLKALHLDPSCLKARISLGYNLQAQGKFQKAWIHFTVGIESNPKSYLAYEGRAVVCLQMSNYFAAMQDINCAIKINSTAEFLTNRGVIHEFMGQQQSAMADYQAAISLNPSYSLAYFNAGNIYLHHRQFSQASDYFSTALKFNPENEYALMNRAVTNSVLKKYEEAEKDFSCAMERCPHWAALYFNRASFYVYLKKYKLAEEDLGIGLSLKPDEAIMYNLRAQVRGKMGLIAEAMSDYNQALDL 1850
BLAST of TPR_REGION domain-containing protein vs. Ensembl Mouse
Match: Ogt (O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) [Source:MGI Symbol;Acc:MGI:1339639]) HSP 1 Score: 97.0561 bits (240), Expect = 1.201e-19 Identity = 121/528 (22.92%), Postives = 213/528 (40.34%), Query Frame = 2
Query: 2693 VATRGKPSVALLNLLGTTQMKAKRWK--DAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
VA +P+ +L+ G ++ + ++ D + C++ + + P + L++ + + + +S + +K NP AEAY + G G++++ I AL + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + S A YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I +LE+ NR S+ P+ + LY
Sbjct: 8 VADSTEPTKRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQE-------PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAE---AEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVAEQLEK-----NRLPSVHPHHSMLY 513 HSP 2 Score: 87.4261 bits (215), Expect = 1.132e-16 Identity = 98/425 (23.06%), Postives = 170/425 (40.00%), Query Frame = 2
Query: 3119 NCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPI---AYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+C ++ EP L + ++ + + T AIK + A+ N + E+ ++AI+ Y L + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP Y N + A YN A+ + CP + N + +E+A+ +RK +E P A NLA V Q KL+E++ + +I +SP A Y N N L ++Q Q A + ++I P +G+ A+ Y+T++
Sbjct: 43 HCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYK-ERGQLQEAIEHYRHALRLKPDF---IDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRL----CPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 456 HSP 3 Score: 75.485 bits (184), Expect = 4.482e-13 Identity = 90/418 (21.53%), Postives = 175/418 (41.87%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
AI+ +P +EAYS +Y++ G+ + A+E Y +RL+P+ Y+N+ +AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A N A+ L P ++ + G +E A R+A E+ NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 472 HSP 4 Score: 51.9878 bits (123), Expect = 6.683e-6 Identity = 78/377 (20.69%), Postives = 138/377 (36.60%), Query Frame = 2
Query: 1484 RPN-AFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL--AAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM----NKYEDAIKDI----------NRAIHLFPDRSNFYMLRGDFYLAMGK 2563
+PN A S G ++ G + A A++++P+ + AY + A+ L N+ + + + A +Y G I LAI +AI L P +AY A ++ G A + YN +RL P + ++ + L + EQ + A + + L +P A + + + + Q+AL + I + P AY G L++ + +G L T+ I N AH NL I+ + G+ +++ + L P + AY C Q+ Y++ +K + NR + P S Y L F A+ +
Sbjct: 187 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSL--NNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQD------------------------VQGALQCYTR-----------AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY-CNLAHCLQIVCDWTDYDERMKKLVSIVAEQLEKNRLPSVHPHHSMLYPLSHGFRKAIAE 525
BLAST of TPR_REGION domain-containing protein vs. Ensembl Mouse
Match: Ogt (O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) [Source:MGI Symbol;Acc:MGI:1339639]) HSP 1 Score: 95.5153 bits (236), Expect = 3.917e-19 Identity = 114/477 (23.90%), Postives = 192/477 (40.25%), Query Frame = 2
Query: 2840 PGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
P + L++ + + + +S + +K NP AEAY + G G++++ I AL + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + S A YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I +LE+ NR S+ P+ + LY
Sbjct: 42 PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAE---AEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVAEQLEK-----NRLPSVHPHHSMLY 503 HSP 2 Score: 87.0409 bits (214), Expect = 1.323e-16 Identity = 98/425 (23.06%), Postives = 170/425 (40.00%), Query Frame = 2
Query: 3119 NCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPI---AYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+C ++ EP L + ++ + + T AIK + A+ N + E+ ++AI+ Y L + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP Y N + A YN A+ + CP + N + +E+A+ +RK +E P A NLA V Q KL+E++ + +I +SP A Y N N L ++Q Q A + ++I P +G+ A+ Y+T++
Sbjct: 33 HCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYK-ERGQLQEAIEHYRHALRLKPDF---IDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRL----CPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 446 HSP 3 Score: 75.485 bits (184), Expect = 4.578e-13 Identity = 90/418 (21.53%), Postives = 175/418 (41.87%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
AI+ +P +EAYS +Y++ G+ + A+E Y +RL+P+ Y+N+ +AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A N A+ L P ++ + G +E A R+A E+ NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 71 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 462 HSP 4 Score: 51.9878 bits (123), Expect = 7.014e-6 Identity = 85/400 (21.25%), Postives = 146/400 (36.50%), Query Frame = 2
Query: 1418 GALFETL--LEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL--AAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM----NKYEDAIKDI----------NRAIHLFPDRSNFYMLRGDFYLAMGK 2563
G L + L LEE K Q A S G ++ G + A A++++P+ + AY + A+ L N+ + + + A +Y G I LAI +AI L P +AY A ++ G A + YN +RL P + ++ + L + EQ + A + + L +P A + + + + Q+AL + I + P AY G L++ ++D +G L T+ I N AH NL I+ + G+ +++ + L P + AY C Q+ Y++ +K + NR + P S Y L F A+ +
Sbjct: 154 GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSL--NNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKE------MQDV------------------QGALQCYTR-----------AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY-CNLAHCLQIVCDWTDYDERMKKLVSIVAEQLEKNRLPSVHPHHSMLYPLSHGFRKAIAE 515
BLAST of TPR_REGION domain-containing protein vs. Ensembl Mouse
Match: Ttc13 (tetratricopeptide repeat domain 13 [Source:MGI Symbol;Acc:MGI:2384573]) HSP 1 Score: 73.9442 bits (180), Expect = 1.172e-12 Identity = 55/230 (23.91%), Postives = 106/230 (46.09%), Query Frame = 2
Query: 2885 ELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINP--RLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDP 3568
++KN + + S + + P+ E + + LG++ + + DL +A+ + P RLY+ R TL+ Y A + + L + A LY+G+ + AI+ F EA+K + I A+ + + E N++ A + + LL++ H + RG++ G +Q AL +F R ++P + Y+ G+ H + E I+ T+ + +DP
Sbjct: 179 DIKNAELALFELSRVIALEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYR---HRGTLYFISEDYATAHEDFQQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYR-ELGNFDAATESFQKALLLNQN---HVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 401 HSP 2 Score: 64.3142 bits (155), Expect = 1.277e-9 Identity = 58/242 (23.97%), Postives = 110/242 (45.45%), Query Frame = 2
Query: 1856 ALEDYNQIIRLQPNNCLAMMKHGLYY-----LNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPY-LAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGK 2563
A+ ++ +++ +P+ A+ G+ Y +I+ +LA + S V+ P E + R + L + +A+ D + I L P+ L Y RG L +E Y A DF SL L ++ M +Y+G+ + EAI F+ + D A+ +LG Y E G+F+ + + L + +++ R + ++A+K+ R + L P ++G ++AMG+
Sbjct: 147 AIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVIALEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARL-YRHRGTLYFISEDYATAHEDFQQSLELNRNQPTAM--LYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQ 385 HSP 3 Score: 63.1586 bits (152), Expect = 2.413e-9 Identity = 50/212 (23.58%), Postives = 96/212 (45.28%), Query Frame = 2
Query: 1958 AAKDFSSVLRHYPSNTEAWLHRGTAYAK-----LQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRK-AEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMA 2575
A + FS++L+ P A RG AY K ++ + AL + S VI L+P+ + +R +L A+ D + + + Y +RG LY ++ ++ A DF+ + N++ A + GL +F +G +++++ L +I AY +AY ++ ++ A + +A+ L + LRG G ++ A
Sbjct: 147 AIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVIALEPDRPEVFEQRAEILSPLGRINEAVNDLT---KAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEA 355 HSP 4 Score: 62.3882 bits (150), Expect = 4.720e-9 Identity = 59/258 (22.87%), Postives = 110/258 (42.64%), Query Frame = 2
Query: 3527 EAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVES--DPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAP 4294
EAIR F+ L +P + A RG + Y D+ E+ + L ++ L P+ + RA + + +N A+ DL +AI++QP S+ LY +RG +Y + D A +D+ +++ + + P A G + H L++A+E F++ ++ D +D + +L Y + + E +++ L+ N R +L+ QEA +F CL++ P
Sbjct: 146 EAIRHFSTMLQEEPDLVSAIYGRG---IAYGKKGLHDIKNA------ELALFELSRVIAL-----------------------EPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQP-SARLYRHRGTLYFISEDYATAHEDFQQSLELNRNQ-PTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFID--AYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEP 367 HSP 5 Score: 61.6178 bits (148), Expect = 7.277e-9 Identity = 63/269 (23.42%), Postives = 112/269 (41.64%), Query Frame = 2
Query: 1652 AIEDLNLILKKDKNYVLAYKSRAGIYASTG-----DISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTS--------GLAADPTYIR 2419
AI + +L+++ + V A R Y G + LA+ LS+ I L PD E + +RAE+ G A+ D + I+LQP+ L + LY+++ E + A +DF L + A L++G + ++A+ F + + AY G R+ + A + S L ++ ++ + RG++ EA+ +F+ + GL + G F + +K T G A P Y+R
Sbjct: 147 AIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVIALEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFIS-EDYATAHEDFQQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATE-SFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLR 413
BLAST of TPR_REGION domain-containing protein vs. Ensembl Mouse
Match: Dnajc7 (DnaJ heat shock protein family (Hsp40) member C7 [Source:MGI Symbol;Acc:MGI:1928373]) HSP 1 Score: 71.2478 bits (173), Expect = 6.174e-12 Identity = 73/352 (20.74%), Postives = 142/352 (40.34%), Query Frame = 2
Query: 2333 GLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLA---RATLFGFKNQYTKAILNCN---------EVLSIEPRCLRA----YLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIV 3340
G Y+ K D+ ++ Y T + P Y RA + ++ +A+ D +++ L ++ G +L++G A ++A E+ H Q+ + ++ +++ +A ++ K FC+++ + P L A C L Y ++Q S ++++ +A+A Y +G C +++ + +AL + P +A +A L K KA N E L I+P ++ Y RG + K++ AI+D T A+K+D I A+ RA C+ + + +E+A++DY V
Sbjct: 35 GNAYYAKKDYNEAYNYYTKAIDMCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEY---------------EKIAEVDF----------EKRDFRKVVFCMDRALE------FAPACHRFKILKAECLAMLGRYPEAQFVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACVACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRQLEDAIEDCTNAVKLDDTYIKAYLRRAQCY-MDTEQFEEAVRDYEKV 354 HSP 2 Score: 54.6842 bits (130), Expect = 8.432e-7 Identity = 72/302 (23.84%), Postives = 112/302 (37.09%), Query Frame = 2
Query: 3380 YINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVV--GVCHHKLKNLKEAIRVFTRCLDHDPKFILAK--VSRGNVFMDYNSSNSRDLAAKDYNSV-----------------------------------------LEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPL----DGRAIVCMQMSDLNGALKDLN---------EAIRIQPQ----SSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDE 4099
Y NR + LG + AL D Q+++ +D +V + G CH L N A R F R L+ D K A+ N M+Y D +D+ V L +DS + DAL G C + +KA F A+ P+ E+ + +A+ + D N A K+ N EA+ I P ++ LY NRG V +R A++D A+ + AY Y+ Q E+A+ + K +++ E
Sbjct: 65 YGNRAATLMMLGRFREALGDA--QQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAEVDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQFVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACVACRNAKALKA-KKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRQLEDAIEDCTNAVKLDDTYIK-AYLRRAQCYMDTEQFEEAVRDYEKVYQTEKTKE 362
BLAST of TPR_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q86TZ1|TTC6_HUMAN (Tetratricopeptide repeat protein 6 OS=Homo sapiens OX=9606 GN=TTC6 PE=2 SV=1) HSP 1 Score: 266.159 bits (679), Expect = 5.435e-76 Identity = 154/423 (36.41%), Postives = 233/423 (55.08%), Query Frame = 2
Query: 3128 EVLSIEPRCLR----AYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+ +I CL Y+ G L+ Y LAI D T AI +D N AF+NRA+C+ + + + A+ DY IVLL+ + ++NRGL+Y+ELG AL DF +A I + + + +CHH++ +EA+ FT L +P F+ A V RGN +M+Y + A KD+ L I+ ++ A ++ G+ QAQGKF+KAW+ FT+AI+ P + +GRA+VC+QM + A++D+N A++I + L NRGV+++ M K AMKDY AI + K +AYFNAG +Y H+ Q QA + F K ++ DP +E +N A+ K EE+ E I P A +YFNRA+ + L++Y+ AE D L + P+D V R R K G A+ DY ++
Sbjct: 95 DATAISADCLYNLGLCYMEEGNLQ---MTYKLAITDLTTAISMDKNSYTAFYNRALCYT-KIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFL-TNRGVIHEFMGHKQNAMKDYQDAITLNP-KYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQAL 511 HSP 2 Score: 127.487 bits (319), Expect = 4.200e-29 Identity = 138/586 (23.55%), Postives = 236/586 (40.27%), Query Frame = 2
Query: 2555 MGKMEMAAICVRQAAEISHNLGQ-SPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKN----YKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGD---VQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRI 4288
M ++A + Q AE+ L + SP+QQAL++SF +++D+AI+ L + + + + LL QMKAKR K+A+ L+ + ++ +A+ + + CY+E N YK + + + ++ N A+Y++ C ++ +++ + D L +L+ E + L +L RG++ ++ Y A++DF +A I A+C + +E+A+ ++ L I+ AY+ RG Y+E G + A DF++A I P + G ++A FT +D DPK LA R V C Q F DI A K + L R ++ M A+KD +AI + P+ S+ Y N G +Y R A ++KA+ + N + E+A E F +ES P A + N A Y + E + E +N+++SL PN A +Y RA V + +EA D+ L +
Sbjct: 2 MKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVL--------------------------LLDATETVK-----LNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHH-RINEFEEAVNFFTWALKINPCF---LDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVV------------------------------------CLQMGNNFAAMQDI--NAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDP-ENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDL 513 HSP 3 Score: 99.7525 bits (247), Expect = 4.227e-20 Identity = 95/399 (23.81%), Postives = 174/399 (43.61%), Query Frame = 2
Query: 1529 KMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVL---AYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNI---EQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCL-LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMA------AICVRQAAEISHNL-GQSPVQQALVHSFLQHYDQAID 2683
+M Y +A + D+ AIS++ + A++ R L + ++QMA+ D ++L D + + +R IY G A+ + QA +S + A + + E A+ + +++ P A + G Y+ E + A KDF L P+ +A + G ++Q A F+ I DP NYLAY R + L+ + A++D + ++ + ++ E + + RG+++ A+ D++ I N A+ N G IYF F ++ Y + L DP RA + KYE+A +D I P + Y R FY + + E+A A+ ++ + +N + + L+ + Y+QA+D
Sbjct: 118 QMTYKLAIT-DLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTN---RGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALD 512 HSP 4 Score: 80.4925 bits (197), Expect = 4.797e-14 Identity = 101/435 (23.22%), Postives = 177/435 (40.69%), Query Frame = 2
Query: 1751 LAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAM---MKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTA--YAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPS--VALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRAL 3034
LAI++L+ AI + + A+ RA Y + E ++AL DY ++ L + + + GL Y+ + Q+ A +DF S T L TA + ++ ++++A+ F+ + ++P AY RG SYM G AT +A DF + N A ++ G +G F+K+ + T + DP AY RA QM A++DIN A+ + + F RG + MG + A + A ++ + ++ + + QA D A + P L+N T K++++A F +E P A + F A Y LK Y+ ++ + + + PN A Y + R ++G +++ + D N+AL
Sbjct: 123 LAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAA--LISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRG----------------------------NSYMEYGHDEAT----KQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKI-STTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNR-AITNTILKKYEEAKEDFANVIESC----------PFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQAL 511 HSP 5 Score: 58.151 bits (139), Expect = 5.582e-7 Identity = 59/239 (24.69%), Postives = 94/239 (39.33%), Query Frame = 2
Query: 1511 RGALYRKMGYLVA---ASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIH----------------------------------LDPNNYLAY 2116
RG Y + G+ A A KD A+ I P I A K Q A + + D LAY+ RA + G+ A+ +++ A+++S +E + R ++E G + A++DY I L P LA G Y + Q+ A+ FS L+ P N ++R L+++++A DF+ VI L PN+ L Y
Sbjct: 250 RGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVY 487
BLAST of TPR_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9M8Y0|SEC_ARATH (Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC OS=Arabidopsis thaliana OX=3702 GN=SEC PE=1 SV=1) HSP 1 Score: 103.605 bits (257), Expect = 7.624e-21 Identity = 98/410 (23.90%), Postives = 167/410 (40.73%), Query Frame = 2
Query: 2861 FLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDP 4090
L+ Y +L+ Y ++I P AE Y + G + I A+ + P A+ A+ + K + ++A C + LS+ P + A+ G L A + EA++I +A+ N A F E + +A+Q Y + + A AY+N G VY LG A+ + A ++PN + +++ L AIR + + L DP+F+ A + GN D D A + YN L + H A+ NLG A +F + P + AI+ Q + + A+ NE +RI P ++ +NRG Y+ + A++DY AI A+ N Y + +E A+ +++ + P
Sbjct: 91 LLIGAIYYQLQEYDMCIARNEEALRIQPQFAECYGNMANAWKEKGDTDRAIRYYLIAIELRPNFADAWSNLASAYMRKGRLSEATQCCQQALSLNPLLVDAHSNLGNLMKAQGLIHEAYSCYLEAVRIQPTFAIAWSNLAGLF-MESGDLNRALQYYKEAVKLKPAFP---DAYLNLGNVYKALGRPTEAIMCYQHALQMRPNSAMAFGNIASIYYEQGQLDLAIRHYKQALSRDPRFLEAYNNLGNALKDIGRV---DEAVRCYNQCLALQPNHPQAMANLGNIYMEWNMMGPASSLFKATLAVTTGLSAPFNNLAIIYKQQGNYSDAISCYNEVLRIDPLAADALVNRGNTYKEIGRVTEAIQDYMHAINFRPTMAE-AHANLASAYKDSGHVEAAITSYKQALLLRP 492 HSP 2 Score: 80.4925 bits (197), Expect = 9.061e-14 Identity = 94/437 (21.51%), Postives = 177/437 (40.50%), Query Frame = 2
Query: 3101 YTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQP-------NDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+ +A+ + N V P L G + Y+++ Y + I EA++I + N A + EK + ++AI+ Y I + + A+ N Y+ G + A +A ++ P N ++ G+ H EA+R+ P F +A + +FM+ S + A + Y +++ DA +NLG +A G+ +A + A++ PNS A + + L+ A++ +A+ P+ Y N G + + A++ YN+ + + P A N G +Y+ + A F+ T+ A + NLA++Y Q ++I N + + P +A NR N ++ R EA D+ + P +G A+ YK ++ +
Sbjct: 69 FKQALEHSNMVYQRNPLRTDNLLLIGAIYYQLQEYDMCIARNEEALRIQPQFAECYGNMANAWK-EKGDTDRAIRYYLIAIELRPNFA---DAWSNLASAYMRKGRLSEATQCCQQALSLNPLLVDAHSNLGNLMKAQGLIHEAYSCYLEAVRI-------QPTFAIAWSNLAGLFME---SGDLNRALQYYKEAVKLKPAFPDAYLNLGNVYKALGRPTEAIMCYQHALQMRPNSAMAFGNIASIYYEQGQLDLAIRHYKQALSRDPRFLEAYNNLGNALKDIGRVDEAVRCYNQCLALQP-NHPQAMANLGNIYMEWNMMGPASSLFKATLAVTTGLSAPFNNLAIIYKQQGNYSDAISCYNEVLRIDPLAADALVNRGNTYKEIGRVTEAIQDYMHAINFRPTMAEAHANLASAYKDSGHVEAAITSYKQALLL 490 HSP 3 Score: 76.6406 bits (187), Expect = 1.428e-12 Identity = 80/349 (22.92%), Postives = 146/349 (41.83%), Query Frame = 2
Query: 1484 RPN-AFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCL-----LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPD 2512
RPN A S + Y + G L A++ A+S+ P L+ A+ L I A ++ + +A+ + AG++ +GD++ A+ +A++L P +AY +Y+ G A+ Y ++++PN+ +A Y Q LA + + L P EA+ + G A + + +A+ ++ + L PN+ A G + + L +++ L + N+ I+Y +S+AI + V+ + A VN G Y E G ++++ + PT A+ A AY E AI +A+ L PD
Sbjct: 151 RPNFADAWSNLASAYMRKGRLSEATQCCQQALSLNPLLVDAHSNLGNLMKAQGLIHEAYSCYLEAVRIQPTFAIAWSNLAGLFMESGDLNRALQYYKEAVKLKPAFPDAYLNLGNVYKALGRPTEAIMCYQHALQMRPNSAMAFGNIASIYYEQGQLDLAIRHYKQALSRDPRFLEAYNNLGNALKDIGRVDEAVRCYNQCLALQPNHPQAMANLGNIYMEWNMMGPASSLFKATLAVTTGLSAPFNNL------AIIYKQQGNYSDAISCYNEVLRIDPLAADALVNRGNTYKEIGRVTEAIQDYMHAINFRPTMAEAHANLASAYKDSGHVEAAITSYKQALLLRPD 493 HSP 4 Score: 69.707 bits (169), Expect = 1.826e-10 Identity = 69/305 (22.62%), Postives = 124/305 (40.66%), Query Frame = 2
Query: 3413 GDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGD 4327
GD + AL P L ++G +++L+ I L P+F GN+ + D A + Y +E+ DA NL +G+ +A A+ +P + ++ A EA+RIQP ++ + N ++ D A++ Y +A+ + P AY N G VY + +A+ C++ ++ P + N+A +Y Q +L+ +I + +++S P Y N N L D+ R EA + CL + P+ P + G+
Sbjct: 67 GDFKQALEHSNMVYQRNPLRTDNLLLIGAIYYQLQEYDMCIARNEEALRIQPQF---AECYGNMANAWKEKGDTDRAIRYYLIAIELRPNFADAWSNLASAYMRKGRLSEATQCCQQALSLNPLLVDAHSNLGNLMKAQGLIHEAYSCYLEAVRIQPTFAIAWSNLAGLFMESGDLNRALQYYKEAVKLKP-AFPDAYLNLGNVYKALGRPTEAIMCYQHALQMRPNSAMAFGNIASIYYEQGQLDLAIRHYKQALSRDPRFLEAYNNLGNALKDIGRVDEAVRCYNQCLALQPNHPQAMANLGN 367 HSP 5 Score: 67.781 bits (164), Expect = 7.087e-10 Identity = 72/310 (23.23%), Postives = 117/310 (37.74%), Query Frame = 2
Query: 1493 AFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRA 2422
A S L+ + G L A + +A+ ++P AY ++ + AI L+ N +A+ + A IY G + LAI + QA+ P EAY+ + G A+ YNQ + LQPN+ AM G Y+ A+ F + L + + + Y + + DA++ ++ V+ +DP LA + + RG Y + +EAI D+ I F M AH NL Y + G E ++ L P + A
Sbjct: 223 AIAWSNLAGLFMESGDLNRALQYYKEAVKLKPAFPDAYLNLGNVYKALGRPTEAIMCYQHALQMRPNSAMAFGNIASIYYEQGQLDLAIRHYKQALSRDPRFLEAYNNLGNALKDIGRVDEAVRCYNQCLALQPNHPQAMANLGNIYMEWNMMGPASSLFKATLAVTTGLSAPFNNLAIIYKQQGNYSDAISCYNEVLRIDP-------------------LAAD----------------ALVNRGNTYKEIGRVTEAIQDYMHAINFRPTMAEAHANLASAYKDSGHVEAAITSYKQALLLRPDFPEA 497 HSP 6 Score: 62.7734 bits (151), Expect = 2.828e-8 Identity = 73/385 (18.96%), Postives = 160/385 (41.56%), Query Frame = 2
Query: 1643 IQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFK-RGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKP--SVALLNLLGTTQMKAKRWKDAITSF 2788
+ A+E N++ +++ IY + + I+ +A+R+ P +E Y A +++ G+ A+ Y I L+PN A Y+ + A + L P +A + G +A + + + + P +A+ G + + A++ + ++ L+ + + +Y+ G +Y + +EAI+ ++ + + A N+ IY+E+G + ++++ L+ DP ++ AY A + + ++A++ N+ + L P+ G+ Y+ M A+ + ++ L A+++ +Y AI R P + AL+N G T + R +AI +
Sbjct: 69 FKQALEHSNMVYQRNPLRTDNLLLIGAIYYQLQEYDMCIARNEEALRIQPQFAECYGNMANAWKEKGDTDRAIRYYLIAIELRPNFADAWSNLASAYMRKGRLSEATQCCQQALSLNPLLVDAHSNLGNLMKAQGLIHEAYSCYLEAVRIQPTFAIAWSNLAGLFMESGDLNRALQYYKEAVKLKPAFPD--AYLNLGNVYKALGRPTEAIMCYQHALQMRPNSAMAFGNIASIYYEQGQLDLAIRHYKQALSRDPRFLEAYNNLGNALKDIGRVDEAVRCYNQCLALQPNHPQAMANLGNIYMEWNMMGPASSLFKATLAVTTGLSAPFNNLAIIYKQQGNYSDAISCYNEVLRIDPLAADALVN-RGNTYKEIGRVTEAIQDY 450 HSP 7 Score: 62.7734 bits (151), Expect = 2.900e-8 Identity = 73/343 (21.28%), Postives = 143/343 (41.69%), Query Frame = 2
Query: 1571 AISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRK-AEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQA 2596
AI + P+ A+ ++ ++ A + L + V A+ + + + G I A S +A+R+ P + A+S A L+ ++G+ AL+ Y + ++L+P A + G Y + + A + L+ P++ A+ + + Y + Q A+ + + DP AY G L+ A+R ++ L L+ + M+ + G +Y A F+ + + NL +IY ++G++ ++ L DP A R Y ++ + +AI+D AI+ P + + Y G +E A +QA
Sbjct: 147 AIELRPNFADAWSNLASAYMRKGRLSEATQCCQQALSLNPLLVDAHSNLGNLMKAQGLIHEAYSCYLEAVRIQPTFAIAWSNLAGLFMESGDLNRALQYYKEAVKLKPAFPDAYLNLGNVYKALGRPTEAIMCYQHALQMRPNSAMAFGNIASIYYEQGQLDLAIRHYKQALSRDPRFLEAYNNLGNALKDIGRVDEAVRCYNQCLALQPNHPQAMANL--GNIYMEWNMMGPASSLFKATLAVTTGLSAPFNNLAIIYKQQGNYSDAISCYNEVLRIDPLAADALVNRGNTYKEIGRVTEAIQDYMHAINFRPTMAEAHANLASAYKDSGHVEAAITSYKQA 487 HSP 8 Score: 58.9214 bits (141), Expect = 4.146e-7 Identity = 94/485 (19.38%), Postives = 180/485 (37.11%), Query Frame = 2
Query: 1793 DDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMS-YMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEIS-------HNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPK---------NQYKPW---PPGAANLNFLVARC-------------YLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEP 3148
DD + +LY + G+ + ALE N + + P ++ G Y ++++ + LR P E + + A+ + A+ + I L PN A+ N+ S YM +G + SEA + + N + AH NLG + +G ++ + PT+ A+ A + + A++ A+ L P + Y+ G+ Y A+G+ A +C + A ++ N+ +Q + ++HY QA+ +R + N LG R +A+ + CL L+P N Y W P ++ +A Y + NY + ++ ++I+P A+A ++G +G++ + I D A+ P + +A+ A+ + AI + + L + P
Sbjct: 52 DDDARLALAHQLY-KGGDFKQALEHSNMVYQRNPLRTDNLLLIGAIYYQLQEYDMCIARNEEALRIQPQFAECYGNMANAWKEKGDTDRAIRYYLIAIELRPNFADAW-----------------------------SNLASAYMRKG-------RLSEATQCCQQALSLNPLLVDAHSNLGNLMKAQGLIHEAYSCYLEAVRIQPTFAIAWSNLAGLFMESGDLNRALQYYKEAVKLKPAFPDAYLNLGNVYKALGRPTEAIMCYQHALQMRPNSAMAFGNIASIYYEQGQLDLAIRHYKQAL------SRDPRFLEAYNNLGNALKDIGRVDEAVRCYNQCLA-LQPNHPQAMANLGNIYMEWNMMGPASSLFKATLAVTTGLSAPFNNLAIIYKQQGNYSDAISCYNEVLRIDPLAADALVNRGNTYKEIGRVTEAIQDYMHAINFRPTMAEAHANLASAYKDSGHVEAAITSYKQALLLRP 492
BLAST of TPR_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q27HV0|OGT1_PIG (UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Sus scrofa OX=9823 GN=OGT PE=2 SV=1) HSP 1 Score: 97.8265 bits (242), Expect = 5.732e-19 Identity = 121/528 (22.92%), Postives = 214/528 (40.53%), Query Frame = 2
Query: 2693 VATRGKPSVALLNLLGTTQMKAKRWK--DAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
VA +P+ +L+ G ++ + ++ D + C++ + + P + L++ + + + +S + +K NP AEAY + G G++++ I AL + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + S A YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I ++LE+ NR S+ P+ + LY
Sbjct: 8 VADSTEPTKRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQE-------PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAE---AEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEK-----NRLPSVHPHHSMLY 513 HSP 2 Score: 87.0409 bits (214), Expect = 9.307e-16 Identity = 98/425 (23.06%), Postives = 170/425 (40.00%), Query Frame = 2
Query: 3119 NCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPI---AYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+C ++ EP L + ++ + + T AIK + A+ N + E+ ++AI+ Y L + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP Y N + A YN A+ + CP + N + +E+A+ +RK +E P A NLA V Q KL+E++ + +I +SP A Y N N L ++Q Q A + ++I P +G+ A+ Y+T++
Sbjct: 43 HCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYK-ERGQLQEAIEHYRHALRLKPDF---IDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRL----CPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 456 HSP 3 Score: 75.485 bits (184), Expect = 3.189e-12 Identity = 90/418 (21.53%), Postives = 175/418 (41.87%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
AI+ +P +EAYS +Y++ G+ + A+E Y +RL+P+ Y+N+ +AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A N A+ L P ++ + G +E A R+A E+ NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 472
BLAST of TPR_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|P81436|OGT1_RABIT (UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Oryctolagus cuniculus OX=9986 GN=OGT PE=1 SV=2) HSP 1 Score: 97.4413 bits (241), Expect = 7.027e-19 Identity = 121/528 (22.92%), Postives = 214/528 (40.53%), Query Frame = 2
Query: 2693 VATRGKPSVALLNLLGTTQMKAKRWK--DAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
VA +P+ +L+ G ++ + ++ D + C++ + + P + L++ + + + +S + +K NP AEAY + G G++++ I AL + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + S A YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I ++LE+ NR S+ P+ + LY
Sbjct: 8 VADSTEPTKRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQE-------PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAE---AEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEK-----NRLPSVHPHHSMLY 513 HSP 2 Score: 87.0409 bits (214), Expect = 1.039e-15 Identity = 98/425 (23.06%), Postives = 170/425 (40.00%), Query Frame = 2
Query: 3119 NCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPI---AYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+C ++ EP L + ++ + + T AIK + A+ N + E+ ++AI+ Y L + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP Y N + A YN A+ + CP + N + +E+A+ +RK +E P A NLA V Q KL+E++ + +I +SP A Y N N L ++Q Q A + ++I P +G+ A+ Y+T++
Sbjct: 43 HCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYK-ERGQLQEAIEHYRHALRLKPDF---IDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRL----CPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 456 HSP 3 Score: 75.485 bits (184), Expect = 3.590e-12 Identity = 90/418 (21.53%), Postives = 175/418 (41.87%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
AI+ +P +EAYS +Y++ G+ + A+E Y +RL+P+ Y+N+ +AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A N A+ L P ++ + G +E A R+A E+ NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 472
BLAST of TPR_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|O15294|OGT1_HUMAN (UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3) HSP 1 Score: 97.4413 bits (241), Expect = 7.332e-19 Identity = 121/528 (22.92%), Postives = 214/528 (40.53%), Query Frame = 2
Query: 2693 VATRGKPSVALLNLLGTTQMKAKRWK--DAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
VA +P+ +L+ G ++ + ++ D + C++ + + P + L++ + + + +S + +K NP AEAY + G G++++ I AL + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + S A YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I ++LE+ NR S+ P+ + LY
Sbjct: 8 VADSTEPTKRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQE-------PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAE---AEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEK-----NRLPSVHPHHSMLY 513 HSP 2 Score: 87.0409 bits (214), Expect = 1.084e-15 Identity = 98/425 (23.06%), Postives = 170/425 (40.00%), Query Frame = 2
Query: 3119 NCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPI---AYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+C ++ EP L + ++ + + T AIK + A+ N + E+ ++AI+ Y L + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP Y N + A YN A+ + CP + N + +E+A+ +RK +E P A NLA V Q KL+E++ + +I +SP A Y N N L ++Q Q A + ++I P +G+ A+ Y+T++
Sbjct: 43 HCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYK-ERGQLQEAIEHYRHALRLKPDF---IDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRL----CPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 456 HSP 3 Score: 75.485 bits (184), Expect = 3.652e-12 Identity = 90/418 (21.53%), Postives = 175/418 (41.87%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
AI+ +P +EAYS +Y++ G+ + A+E Y +RL+P+ Y+N+ +AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A N A+ L P ++ + G +E A R+A E+ NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 472
BLAST of TPR_REGION domain-containing protein vs. TrEMBL
Match: A0A1S3JZA6 (uncharacterized protein LOC106177489 OS=Lingula unguis OX=7574 GN=LOC106177489 PE=4 SV=1) HSP 1 Score: 999.964 bits (2584), Expect = 0.000e+0 Identity = 532/1287 (41.34%), Postives = 799/1287 (62.08%), Query Frame = 2
Query: 584 IIHQRKRCTSVPNRHWLEEDSLIVHLEYHQIMDEINIQRQKIRALKNTSEINEDINEKKPLEE--DEKIFNDN-FDSGILTTNVENEYKTHQSVKSIEDDCSSPAKNALRAGQNYIYYXXXXXXXXXXXXXXNIARISDIERFLGQPPNKLDKTKSFENIRIELKRIRSCXXXXXXXXXXXXXXXXADIHNFEDWSKNRGYKKESNARDWITVIWDQWFDEIYPPIPDHIIDLTSDKPSETPYKNELLNREPTSVSAIQNEILDLPENIEPVLDEVDEEFRGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGD-FEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYIXXXXXXXXXXNNCC 4432
+ + +R S+PN + +ED L + ++ MDEI Q ++I+ K + +K P+++ +E I +++ +G+ T + + K DD + A+ AL AG+ Y+ YP +K+ K P ++AR+ +IERFL PP KL++T+S + + ++R+ R +K +S+ DI +F+ +++ RGYK E + R+W IW+ WFDE++PP + + S + R S + I ++ + IEP+ D +E L L +EV+ +S+ + P AF L RRGA+YRK+G + +D++ AI++EP L+ AYW RHLLHL+ K A+EDLN +L+ K + AY+SRA IY +GD+++AI N +QAI+L P+D EAY +RAE+YE++GE RLALEDY RL P A+ KHGLYY N + WQ DF+ +L+ P+N EA +RG A+AK+ QW A+ D SA IHLDPNN +A++ RGCLLRK +P A++D S+S++L+ + N+M+Y +RGILY +T + +AI DFE V+ +KD+ AHVNLGLIY + D + +++ ++ + DPTYIRAY CRAEAY +++ + +A+ D RAIHL PD ++YM RG L MG +E+AA CVR A+E++ LGQSP+QQA+V SFL++YD+AI AL ATR KP +L LLG TQMKAK W++AI +F L LKP + WP AA +++L+ C +EL+ Y ++ AF+ +K++ +AEA+Y +G R+RL K +GI D NRALA++P+++Q YL+RA +G + QY+KAILNCNE + ++P +RAYL+RG LKY IKAY LAI+D T+A ID+ C LA+FNRAVC++ + KN+ KA+QDY IVLL+ DAL L K INRGL+Y + D +NAL DF+ A I + + + +G+C+HKL L++A++ F+ L D F+ + RGNV MDY A +DY L+++ +L A VNL + Q GK+ AW FT A+ +P + L+GRAIV +QMSD A +D+N ++R+ P + +L NRGV++Q M DK AM+DY +AI I +AYFNA +Y Q +QA + K + +P DE+ +N A+ + +++ ++ LSP+SA++YFNR N+ L+++ +AE D+ L + PDD V K R D R K G A+ DYK ++ I S N+
Sbjct: 1027 VFPKPRRTNSMPNLYGDDEDFLFIPQDFSTAMDEITKQMKQIKEAK--------LGKKTPVQQLPEEVIESESGAKTGVARTRSPTTEQRVYTRKQEYDDKPTLAEEALEAGRKYVMYPKRKKKKMVPL---DMARLEEIERFLAMPPGKLERTESLPKVNVPVERL----LRVPQYVKNKHRRSIPDILDFDSFAEKRGYKGE-DEREWTRDIWNAWFDEVFPPTQSERDEDEARAMSAMSSTTDRSVRSKGHASVVSTHISEVIDEIEPLAD-TEENAEAILL--LQDEVEKLSELISQSPTPTAFDLCRRGAIYRKLGQIKLGLEDLDRAIALEPMLLDAYWHRHLLHLLKGKKNDALEDLNFLLRHSKQHAGAYRSRAEIYRESGDVTMAIVNFNQAIKLDPNDHEAYYRRAEMYEKSGEMRLALEDYAIATRLAPEKTEALFKHGLYYFNSQNWQPCINDFTDLLKVEPNNAEARTYRGRAFAKMSQWTPAIEDLSAAIHLDPNNSVAHYHRGCLLRKLQPKKALQDLSVSIILDDGDSNVMAYFHRGILYNSTGRPEDAIPDFETVLKLDKDIASAHVNLGLIYMTQLDNVQNAIRKFSAAIKVDPTYIRAYVCRAEAYHRIHDHRNALLDFTRAIHLKPDTHHYYMYRGQLVLEMGNLELAAFCVRHASELNAGLGQSPMQQAVVQSFLKNYDKAIGALESATRQKPVASLFTLLGKTQMKAKLWRNAIGNFDKALGILKPWSDKDSWPHEAAEVHYLIGMCNMELRGYLEAHEAFNNAIKVDGTNAEAFYQRGLSRIRL-KQGKGIQDFNRALALDPKIFQVYLSRAAYYGLRGQYSKAILNCNEAIKLQPNSVRAYLFRGALKYHIKAYQLAIRDLTKATSIDSTCALAYFNRAVCYH-DSKNHAKALQDYGIVLLLGDALRL--KVLINRGLLYFDRDDYRNALQDFLLAAKIDAKNCKIYHTIGLCYHKLNCLEDAVKAFSVALTLDKFFLEGYIGRGNVLMDYGHDAGLKFARRDYERALQLNPIYLPARVNLAYNLQVCGKYMHAWRQFTAALTANPYYKPALEGRAIVNLQMSDTFAAFQDINASVRVVPSAELL-TNRGVIHQFMGDKANAMRDYQQAISIDPSHA-LAYFNAANIYFQMRQFKQAHAHYDKAILFNPKDESALLNRAITKVLLRDSAGALDDFKAAVKLSPHSAHMYFNRGNLYSSLKQFDKAEKDYTKALTLQPDDALVYKRRADVRGKLGKKAEAIADYKYAIEIQSKKRATIDANSVT 2288
BLAST of TPR_REGION domain-containing protein vs. TrEMBL
Match: A0A267G818 (TPR_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000887g9 PE=4 SV=1) HSP 1 Score: 943.725 bits (2438), Expect = 0.000e+0 Identity = 558/1526 (36.57%), Postives = 845/1526 (55.37%), Query Frame = 2
Query: 167 ERIISQKNEIEKWRTKANEMLN----------------------LTSEIEIVGTFIS--PSEPKIIDIWQPLAPRLFMSQNQVTNVLCPKYNPNI-----------FEPTIEEVSK-QNTFENF--------------TSEDLTLSNEASFCNEIDLEALETKERLLSRKINSVECLADERIDENKFSKIIHQRKRCTSVPNRHWLEEDSLIVHLEYHQIMDEINIQRQKIRALKNTSEINEDINEKKP----------LEEDEKIFNDNFDSGILTTNVENEYKTHQSVK--SIEDDCSSPAKNALRAGQNYIYYXXXXXXXXXXXXXX--------NIARISDIERFLGQPPNKLDKTKSFENIRI----EL---KRIRSCXXXXXXXXXXXXXXXXADIHNFEDWSKNRGYKKESNARDWITVIWDQWFDEIYPPIP---DHIID---------------LTSDKPSETPYKNE--LLNREP----------TSVSAIQNEILDLPENIEPVLDEVDEEFRGALFETLLEEVKNISKDMENYQR----PNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNL----GQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKP--WPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYL-ELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+RI+ + E W+ +A E L T ++E+VG+ + + +D+ +P PR QV L +Y + F P + Q +F + D+ + E++ AL T+ RL +R S+E L E +E R R S+P H EED+L+++L+Y+ I E+ Q + + +N ++NE + ++E E+ + +G T+ + + + ++ +I++ +PA+ AL AG+ Y+ P + + + ++ ++ARI IERFL +P N+L + +S ++++ EL KRIRS + R + +F W+ GY+ + + RDW+ +WD+WFDE+YPP D + T S++ +E LLN +P +S A + LPE I P LDE+ E R L +EV ++ D+E +R P+AF L RRGAL RK+GYL A +D++ I EP + AYW RHLL ++ N++ A++DLN++LK K+ AYK+RA IY D+++AI N QAI+L+P D++ Y KRA LYE+ GE RLALEDY+ +L P+ A+ KHGLYY EQWQ A DF+ +L P ++ A+ + G YAKLQQ A+ FS+ IHL+P N++A++ RG LLR+A+P A+RD SIS++L EN M++MYRGILY + +AI DFE ++ +D+ AHVNLGL+Y ++ + ++ + DPTYIRA CR +A+ M +Y +A+ DI R IH+ P ++YM+RG+ L MG ++MAA CVR +A ++H G SP Q+ALV SFL +D+AI L R +P +L LLG TQMKAKR+ DA SF CLE LKP K WP AA +++L+ C+ L+NY + +++A + I+ A+ +YH+G CR+ L K +G+ DLN+ALAINP +YQ YL+RA + + +Y+KA+LNCNE L ++P+C+RA LYRG +K +I+AY LA+ D T AI +D C LA+FNRAVC + E + + A++DY +VL+++D L Y+ +NRGL+YL D +NAL DF+ A +PND +L+ +G C+H+L+ L +A+R F+R LD + F A + R N ++D+ S S A +DY VL D HL A VNL F Q G+ + AWD + AI P+S +P + RA+V +QMS+L+GAL D NEA+R++P S+ + RGVV Q D++ AM+DY KA I+ +AY+NA VY+ Q QAL + + +P DE N AL ++ ++ +R+I LSP+ A+ +FNR + + AE DF + L I PDDP VLK+R DC K G A+EDYK +V +
Sbjct: 558 DRIMKEIESYEAWQKRAMEALRQLQADEAEEAAAAAAGVDLNSRRTPQLELVGSRVQFLGQTARRVDMLEPPPPRAQAGPEQVRAALFKQYESALPSDEFGAVGRGFSPVSANAERRQRNGTDFTGTGAAAGAATVGSANGDVVEGIAMTDVVEVEEGAL-TRMRLQNRLSRSIERLNAEYRNEGGVESFFGLR-RSRSLPTVHLDEEDNLVLNLDYNSIEKELQAQTRLMEEEENRVKLNEASQSAEEQQQQSEQGEGVQEGERAGST---AGGEETSAKTDAPRSKVLQQLAIKEPEPTPAQLALAAGRKYVILPRQVQQAQQQQQQLMRQRRGLVSMARIDAIERFLNEPANQLARRESLDSVKKPADWELRVPKRIRSTRRRSLPLNLR---------DDFPAWAAEHGYRGDGDPRDWVPAVWDRWFDEVYPPSSRDGDREVGADAAGGQLQRQPQRQRTDSATSDSAVTDERALLN-DPEFARVRHDSDSSSEAPSEHPVQLPEKIPPALDEIPEADRETAAAILEQEVAKLTADIEAAERLEKLPSAFQLCRRGALRRKLGYLRGAREDLDRCIGQEPRYLDAYWHRHLLKVLENRLSGALDDLNVLLKHTKDNASAYKARAEIYRKKNDVTMAIINYGQAIKLNPSDADCYHKRAGLYEKRGEMRLALEDYSMASKLSPDKTDALFKHGLYYFQNEQWQFAINDFTELLTRDPKDSRAYTYIGRCYAKLQQMIPAVQAFSSAIHLNPYNWIAFYHRGRLLRRAQPDKALRDLSISVMLNEDVENAMAFMYRGILYCEMDRPEDAIPDFETLVRLRQDIPCAHVNLGLVYHHTDRHHLAIHHYSAAINVDPTYIRAVRCRVDAFVAMREYRNALLDITRCIHMNPMDPSYYMVRGEILLKMGNLDMAAFCVRHSAAMNHGRRSAEGASPTQRALVLSFLGQFDEAIRVLAQEARFRPGKDILFLLGKTQMKAKRFADAAGSFQECLEILKPWGGDKKLVWPKEAAQVHYLIGDCHTALQNYGEGLESYTAALAIDSGFADGFYHRGLCRI-LMKQAKGVQDLNQALAINPAMYQVYLSRAAHYACEGRYSKAVLNCNEALRLQPQCVRALLYRGSIKCRIRAYGLAVDDLTRAIAVDPTCALAYFNRAVC-HGESRQPDLALRDYGVVLMLND-RRLRYRTLVNRGLLYLTSCSDPENALGDFLLAARDRPNDERLLHAIGTCYHRLRRLPQAVRAFSRALDANSNFYDAYIGRANCYLDFGSPRSVLFARRDYERVLMSDPRHLAARVNLAFSLQMDGRMRAAWDQLSAAIRFQPDSPKPWECRAVVSLQMSNLDGALADANEAVRLRPSSAESLVTRGVVQQCAGDRVSAMRDYQKA-ILAEPSFSLAYYNAANVYLQQRQYHQALRYYDSCIRLNPADEGAHNNRALTRGLLGDVDGALADASRAIELSPHMAHAFFNRGKLAVRAGNFDSAEADFSAALLIQPDDPVVLKSRADCLGKLGKRQAAIEDYKRAVQL 2064
BLAST of TPR_REGION domain-containing protein vs. TrEMBL
Match: K1PHE8 (Tetratricopeptide repeat protein 6 OS=Crassostrea gigas OX=29159 GN=CGI_10013650 PE=4 SV=1) HSP 1 Score: 942.954 bits (2436), Expect = 0.000e+0 Identity = 543/1314 (41.32%), Postives = 805/1314 (61.26%), Query Frame = 2
Query: 497 ETKERLLSRKINSVECLADERIDENKFSKIIHQRKRCTSVPNRHWLEEDSLIVHLEYHQIMDEINIQRQKIRALK--NTSEINEDINEKKPLE---EDEKIFNDNFDSGILTTNVENEYKTHQSVKSIEDDCSSPAKNALRAGQNYIYYXXXXXXXXXXXXXXNIARISDIERFLGQPPNKLDKTKSFENIRIELKRIRSCXXXXXXXXXXXXXXXXADIHNFEDWSKNRGYKKESNARDWITVIWDQWFDEIYPPIPDHIIDLT----SDKP-SETPYKNELLNREPTSVSAIQNEILDLPENIEPVLDEVDEEFRGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEK-GDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHN--LGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRL---GKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
ETKE ++ + + + D I F + R+ +++ L+ D+L+V +Y+ M+EI+ Q+ +R +K ++ E+ LE + EK+ + ++ YK +K D +PA+ AL+AG+ Y+ P K + KSK K ++ R+ IE+FL PP ++++ S I ++R + R S +++ SL ++ +F+ ++K + + R+W+ +W+ WFD+++PP P D D+P S+T + E + S+S+ I D IEP LD+ ++ L + + EE++ ++ + +P AF L RRGALYRK+G + AA D++ AI +EP L+ AYW RHLL+L+ ++ Q A DL ILK + + AY+S A I + + AI N S AI+L+P D EAY +RA +YE+ + LAL+D+ ++ P A++KH +YY + W A +DF+ +LR P N+ A ++RG A A+ QW A+ D SA IHLDP ++ A+F R C+LRKA P A+ D+S+SLL+ +++N+MSY++RGILY + +F +AI DFE V+ NKD+ AHVNLGLIY ++ +++K T+G+ DPTY+RAY CR EAY +++ A+KD RAIHL PD ++YM RG L +G +EMAA CV+ A+E+S N LG+ P QQA+V SFL++YD+AI+AL ATR KP L LLG TQMKAK +KDAITSF L+ KP + +PWP A+ +FL+ C++ELK Y +++ AF++ VKINPN+A+A Y +G +++L G ++GI D NRALAINPR++QAYL+RA +G K YTKAILNCNE ++PR +RAYLYRG LKY IKAY LAI+D AI ID+ C LAFFNRAVC+ EKKNY K+++DY IVLL+ D L K INRGL+Y D NAL+DF A + P + +L+ +G+C+HK+ LKEA+ VFT CL+ +P F+ ++RGNV+MDY S A +DY VL + HL A VNL + Q GKF AW FT AIE +P + L+GRA+V +QMS+ A +D+ E+I++ P + +L NRGV+ Q M+D++ AMKDY AI + +AYFNA VY H +QAL + VE +P DE+ +N A+ + + ++ +I LSP++A++YFNR N+ ++++ +AE D+ L + PDDP VLK R D K G A+EDYK +V I
Sbjct: 890 ETKEAPVTPVLQRMTEMTDNEI----FPVFVPLRRSTSTLGLSKGLD-DTLLVPQDYNAAMEEISTQKSNVRQMKLNKKLLEAKEKEEESRLEWQLQQEKLAEERAET----------YKEEPKMK----DEPTPAELALQAGRAYVILPKKGKKKSKRKAPISMERLEQIEKFLRAPPKPIERSNSMLKIVPPVER----ELRVSSKVRQGSRLSLPNLLDFDSFTKIKKMPNDCVPREWVRDMWNGWFDQVFPPTPSESEDEEPEYQPDEPVSQTREEKEKEKKRKDSLSSY---ISDALSEIEP-LDDSEQNIE--LHQIIHEEIQKLTGQIA-MGKPKAFDLCRRGALYRKVGMIKAAQIDLDLAIKMEPLLLDAYWHRHLLYLLKDQKQQAKADLTFILKYNNKHGGAYRSMAEILRKENNPNDAIINYSMAIKLNPRDHEAYFQRAAMYEKTDKMPLALDDFMMCKKILPTRTDAILKHAMYYFQQKNWNTAIQDFTDLLRVDPLNSMARMYRGRALAEQNQWNAAVEDLSAAIHLDPKSWQAFFYRACILRKAHPKQALHDYSVSLLINDNDDNVMSYLHRGILYNSMNRFEDAIPDFESVLKLNKDIACAHVNLGLIYMNHYENYHRAIKKFTAGIKVDPTYVRAYVCRGEAYHKIHDLRAALKDFTRAIHLRPDVHHYYMYRGQLVLELGNLEMAAFCVKHASEMSSNSSLGEMPTQQAVVQSFLKNYDKAIEALNAATRVKPVPPLFMLLGKTQMKAKVFKDAITSFDRALQLYKPWRR-EPWPMEASECHFLIGMCHIELKGYHEAKDAFTSAVKINPNYAQALYQRGVAKMKLSSRGLSREGIQDFNRALAINPRIFQAYLSRACYYGMKKNYTKAILNCNEATKLQPRSVRAYLYRGALKYHIKAYDLAIRDLDIAIGIDSTCDLAFFNRAVCYQ-EKKNYHKSLKDYGIVLLLGDDNRLRTKVLINRGLLYFSQKDYTNALYDFKMAAKLDPQNYRILHTLGLCYHKMDRLKEAVGVFTSCLERNPFFLDGIIARGNVYMDYGSQGGIIYARRDYERVLMQNPLHLPARVNLAYTLQVSGKFMHAWRQFTAAIEINPRFKPALEGRAVVNLQMSNTFAAFQDICESIKVSPTAELL-TNRGVINQFMKDRVNAMKDYQNAIRMDPTYS-LAYFNAANVYFHTRHFKQALNYYNSAVEHNPQDESALLNRAITKVMLRDSQGALGDFKAAIKLSPHTAHMYFNRGNLYASMEQFDQAEKDYSKALSLKPDDPLVLKRRADVLGKLGKRDEAIEDYKRAVEI 2169
BLAST of TPR_REGION domain-containing protein vs. TrEMBL
Match: A0A267EN22 (TPR_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000887g4 PE=4 SV=1) HSP 1 Score: 942.569 bits (2435), Expect = 0.000e+0 Identity = 558/1528 (36.52%), Postives = 846/1528 (55.37%), Query Frame = 2
Query: 167 ERIISQKNEIEKWRTKANEMLN----------------------LTSEIEIVGTFIS--PSEPKIIDIWQPLAPRLFMSQNQVTNVLCPKYNPNI-----------FEPTIEEVSK-QNTFENF---------------TSEDLTLSNEASFCNEIDLEALETKERLLSRKINSVECLADERIDENKFSKIIHQRKRCTSVPNRHWLEEDSLIVHLEYHQIMDEINIQRQKIRALKNTSEINEDINEKKP------------LEEDEKIFNDNFDSGILTTNVENEYKTHQSVK--SIEDDCSSPAKNALRAGQNYIYYXXXXXXXXXXXXXX-------NIARISDIERFLGQPPNKLDKTKSFENIRI----EL---KRIRSCXXXXXXXXXXXXXXXXADIHNFEDWSKNRGYKKESNARDWITVIWDQWFDEIYPPI---------PDHIIDLTSDKP---------SETPYKNE--LLNREP----------TSVSAIQNEILDLPENIEPVLDEVDEEFRGALFETLLEEVKNISKDMENYQR----PNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNL----GQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKP--WPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYL-ELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+RI+ + E W+ +A E L T ++E+VG+ + + +D+ +P PR QV L +Y + F P + Q +F + D+ + E++ AL T+ RL +R S+E L E +E R R +S+P H EED+L+++L+Y+ I E+ Q + + +N ++NE + ++E E+ + +G T+ + + + ++ +I++ +PA+ AL AG+ Y+ P + + + ++ ++ARI IERFL +P N+L + +S ++++ EL KRIRS + R + +F W+ GY+ + + RDW+ +WD WFDE+YPP D + +P S++ +E LLN +P +S A + LPE I P LDE+ E R L +EV ++ D+E +R P+AF L RRGAL RK+GYL A +D++ I EP + AYW RHLL ++ N++ A++DLN++LK K+ AYK+RA IY D+++AI N QAI+L+P D++ Y KRA LYE+ GE RLALEDY+ +L P+ A+ KHGLYY EQWQ A DF+ +L P ++ A+ + G YAKLQQ A+ FS+ IHL+P N++A++ RG LLR+A+P A+RD SIS++L EN M++MYRGILY + +AI DFE ++ +D+ AHVNLGL+Y ++ + ++ + DPTYIRA CR +A+ M +Y +A+ DI R IH+ P ++YM+RG+ L MG ++MAA CVR +A ++H G SP Q+ALV SFL +D+AI L R +P +L LLG TQMKAKR+ DA SF CLE LKP K WP AA +++L+ C+ L+NY + +++A + I+ A+ +YH+G CR+ L K +G+ DLN+ALAINP +YQ YL+RA + + +Y+KA+LNCNE L ++P+C+RA LYRG +K +I+AY LA+ D T AI +D C LA+FNRAVC + E + + A++DY +VL+++D L Y+ +NRGL+YL D +NAL DF+ A +PND +L+ +G C+H+L+ L +A+R F+R LD + F A + R N ++D+ S S A +DY VL D HL A VNL F Q G+ + AWD + AI P+S +P + RA+V +QMS+L+GAL D NEA+R++P S+ + RGVV Q D++ AM+DY KA I+ +AY+NA VY+ Q QAL + + +P DE N AL ++ ++ +R+I LSP+ A+ +FNR + + AE DF + L I PDDP VLK+R DC K G A+EDYK +V +
Sbjct: 556 DRIMKEIESYEAWQKRAMEALRQLQADEAEEAAAAAAGVDLNSRRTPQLELVGSRVQFLGQTARRVDMLEPPPPRAQAGPEQVRAALFKQYESALPSDEFGAVGRGFSPVSANAERRQRNGTDFTGTGAAAAGAATVGSANGDVVEGIAMTDVVEVEEGAL-TRMRLQNRLSRSIERLNAEYRNEGGVESFFGLR-RSSSLPTVHLDEEDNLVLNLDYNSIEKELQAQTRLMVEEENRVKLNEASQSAEEQQQQQQSEQGEGVQEGERAGST---AGGEETSAKTDAPRSKVLQQLAIKEPEPTPAQLALAAGRKYVILPRQVQQAQQQQQLMRQRRGLVSMARIDAIERFLNEPANQLARRESLDSVKKPADWELRVPKRIRSTRRRSLPLNLR---------DDFPAWAAEHGYRGDGDPRDWVPAVWDLWFDEVYPPSSRDGDREVGADAAGGQSQRQPQRQWTDSATSDSAVTDERALLN-DPEFARVRHDSDSSSEAPSEHPVQLPEKIPPALDEIPEADRETAAAILEQEVAKLTADIEAAERLEKLPSAFQLCRRGALRRKLGYLRGAREDLDRCIGQEPRYLDAYWHRHLLKVLENRLSGALDDLNVLLKHTKDNASAYKARAEIYRKKNDVTMAIINYGQAIKLNPSDADCYHKRAGLYEKRGEMRLALEDYSMASKLSPDKTDALFKHGLYYFQNEQWQFAINDFTELLTRDPKDSRAYTYIGRCYAKLQQMIPAVQAFSSAIHLNPYNWIAFYHRGRLLRRAQPDKALRDLSISVMLNEDVENAMAFMYRGILYCEMDRPEDAIPDFETLVRLRQDIPCAHVNLGLVYHHTDRHHLAIHHYSAAINVDPTYIRAVRCRVDAFVAMREYRNALLDITRCIHMNPMDPSYYMVRGEILLKMGNLDMAAFCVRHSAAMNHGRRSAEGASPTQRALVLSFLGQFDEAIRVLAEEARFRPGKDILFLLGKTQMKAKRFADAAGSFQECLEILKPWGGDKKLVWPKEAAQVHYLIGDCHTALQNYGEGLESYTAALAIDSGFADGFYHRGLCRI-LMKQAKGVQDLNQALAINPAMYQVYLSRAAHYACEGRYSKAVLNCNEALRLQPQCVRALLYRGSIKCRIRAYGLAVDDLTRAIAVDPTCALAYFNRAVC-HGESRQPDLALRDYGVVLMLND-RRLRYRTLVNRGLLYLTSCSDPENALGDFLLAARDRPNDERLLHAIGTCYHRLRRLPQAVRAFSRALDANSNFYDAYIGRANCYLDFGSPRSVLFARRDYERVLMSDPRHLAARVNLAFSLQMDGRMRAAWDQLSAAIRFQPDSPKPWECRAVVSLQMSNLDGALADANEAVRLRPSSAESLVTRGVVQQCAGDRVSAMRDYQKA-ILAEPSFSLAYYNAANVYLQQRQYHQALRYYDSCIRLNPADEGAHNNRALTRGLLGDVDGALADASRAIELSPHMAHAFFNRGKLAVRAGNFDSAEADFSAALLIQPDDPVVLKSRADCLGKLGKRQAAIEDYKRAVQL 2064
BLAST of TPR_REGION domain-containing protein vs. TrEMBL
Match: A0A267F2Y6 (TPR_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000887g3 PE=4 SV=1) HSP 1 Score: 937.947 bits (2423), Expect = 0.000e+0 Identity = 557/1527 (36.48%), Postives = 842/1527 (55.14%), Query Frame = 2
Query: 167 ERIISQKNEIEKWRTKANEMLN----------------------LTSEIEIVGTFIS--PSEPKIIDIWQPLAPRLFMSQNQVTNVLCPKYNPNI-----------FEPTIEEVSK-QNTFENF--------------TSEDLTLSNEASFCNEIDLEALETKERLLSRKINSVECLADERIDENKFSKIIHQRKRCTSVPNRHWLEEDSLIVHLEYHQIMDEINIQRQKIRALKNTSEINEDINEKKP------------LEEDEKIFNDNFDSGILTTNVENEYKTHQSVK--SIEDDCSSPAKNALRAGQNYIYYXXXXXXXXXXXXXX-------NIARISDIERFLGQPPNKLDKTKSFENIRI----EL---KRIRSCXXXXXXXXXXXXXXXXADIHNFEDWSKNRGYKKESNARDWITVIWDQWFDEIYPPIP---DHIID---------------LTSDKPSETPYKNE--LLNREP----------TSVSAIQNEILDLPENIEPVLDEVDEEFRGALFETLLEEVKNISKDMENYQR----PNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNL----GQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKP--WPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYL-ELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+RI+ + E W+ +A E L T ++E+VG+ + + +D+ +P PR QV L +Y + F P + Q +F + D+ + E++ AL T+ RL +R S+E L E +E R R S+P H EED+L+++L+Y+ I E+ Q + + +N ++NE + ++E E+ + +G T+ + + + ++ +I++ +PA+ AL AG+ Y+ P + + + ++ ++ARI IERFL +P N+L + +S ++++ EL KRIRS + R + +F W+ GY+ + + RDW+ +WD WFDE+YPP D + T S++ +E LLN +P +S A + LPE I P LDE+ E R L +EV ++ D+E +R P+AF L RRGAL RK+GYL A +D++ I EP + AYW RHLL ++ N++ A++DLN++LK K+ AYK+RA IY D+++AI N QAI+L+P D++ Y KRA LYE+ GE RLALEDY+ +L P+ A+ KHGLYY EQWQ A DF+ +L P ++ A+ + G YAKLQQ A+ FS+ IHL+P N++A++ RG LLR+A+P A+RD SIS++L EN M++MYRGILY + +AI DFE ++ +D+ AHVNLGL+Y ++ + ++ + DPTYIRA CR +A+ M +Y +A+ DI R IH+ P ++YM+RG+ L MG ++MAA CVR +A ++H G SP Q+ALV SFL +D+AI L R +P +L LLG TQMKAKR+ DA SF CLE LKP K WP AA +++L+ C+ L+NY + +++A + I+ A+ +YH+G CR+ L K +G+ DLN+ALAINP +YQ YL+RA + + +Y+KA+LNCNE L ++P+C+RA LYRG +K +I+AY LA+ D T AI +D C LA+FNRAVC + E + + A++DY +VL+++D L Y+ +NRGL+YL D +NAL DF+ A +PND +L+ +G C+H+L+ L +A+R F+R LD + F A + R N ++D+ S S A +DY VL D HL A VNL F Q G+ + AWD + AI P+S +P + RA+V +QMS+L+GAL D NEA+R++P S+ RGVV Q D++ AM+DY KA I+ +AY+NA VY+ Q QAL + + +P DE N AL ++ ++ +R+I LSP+ + +FNR + + AE DF + L I PDDP VLK+R DC K G A+EDYK +V +
Sbjct: 556 DRIMKEIESYEAWQKRAMEALRQLQADEAEEAAAAAAGVDLNSRRTPQLELVGSRVQFLGQTARRVDMLEPPPPRAQAGPEQVRAALFKQYESALPSDEFGAVGRGFSPVSANAERRQRNGTDFTGTGAAAGAAMVGSANGDVVEGIAMTDVVEVEEGAL-TRMRLQNRLSRSIERLNAEYRNEGGVESFFGLR-RSRSLPTVHLDEEDNLVLNLDYNSIEKELQAQTRLMVEEENRVKLNEASQSAEEQQQQQQSEQGEGVQEGERAGST---AGGEETSAKTDAPRSKVLQQLAIKEPEPTPAQLALAAGRKYVILPRQVQQAQQQQQLMRQRRGLVSMARIDAIERFLNEPANQLARRESLDSVKKPADWELRVPKRIRSTRRRSLPLNLR---------DDFPAWAAEHGYRGDGDPRDWVPAVWDLWFDEVYPPSSRDGDREVGADAAGGQSQRQPQRQRTDSATSDSAVTDERALLN-DPEFARVRHDSDSSSEAPSEHPVQLPEKIPPALDEIPEADRETAAAILEQEVAKLTADIEAAERLEKLPSAFQLCRRGALRRKLGYLRGAREDLDRCIGQEPRYLDAYWHRHLLKVLENRLSGALDDLNVLLKHTKDNASAYKARAEIYRKKNDVTMAIINYGQAIKLNPSDADCYHKRAGLYEKRGEMRLALEDYSMASKLSPDKTDALFKHGLYYFQNEQWQFAINDFTELLTRDPKDSRAYTYIGRCYAKLQQMIPAVQAFSSAIHLNPYNWIAFYHRGRLLRRAQPDKALRDLSISVMLNEDVENAMAFMYRGILYCEMDRPEDAIPDFETLVRLRQDIPCAHVNLGLVYHHTDRHHLAIHHYSAAINVDPTYIRAVRCRVDAFVAMREYRNALLDITRCIHMNPMDPSYYMVRGEILLKMGNLDMAAFCVRHSAAMNHGRRSAEGASPTQRALVLSFLGQFDEAIRVLAEEARFRPGKDILFLLGKTQMKAKRFADAAGSFQECLEILKPWGGDKKLVWPKEAAQVHYLIGDCHTALQNYGEGLESYTAALAIDSGFADGFYHRGLCRI-LMKQAKGVQDLNQALAINPAMYQVYLSRAAHYACEGRYSKAVLNCNEALRLQPQCVRALLYRGSIKCRIRAYGLAVDDLTRAIAVDPTCALAYFNRAVC-HGESRQPDLALRDYGVVLMLNDR-RLRYRTLVNRGLLYLTSCSDPENALGDFLLAARDRPNDERLLHAIGTCYHRLRRLPQAVRAFSRALDANSNFYDAYIGRANCYLDFGSPRSVLFARRDYERVLMSDPRHLAARVNLAFSLQMDGRMRAAWDQLSAAIRFQPDSPKPWECRAVVSLQMSNLDGALADANEAVRLRPSSAESLATRGVVQQCAGDRVSAMRDYQKA-ILAEPSFSLAYYNAANVYLQQRQYHQALRYYDSCIRLNPADEGAHNNRALTRGLLGDVDGALADASRAIELSPHMVHAFFNRGKLAVRAGNFDSAEADFSAALLIQPDDPVVLKSRADCLGKLGKRQAAIEDYKRAVQL 2063
BLAST of TPR_REGION domain-containing protein vs. Ensembl Cavefish
Match: ttc6 (tetratricopeptide repeat domain 6 [Source:ZFIN;Acc:ZDB-GENE-090429-2]) HSP 1 Score: 786.563 bits (2030), Expect = 0.000e+0 Identity = 427/1070 (39.91%), Postives = 644/1070 (60.19%), Query Frame = 2
Query: 1196 RDWITVIWDQWFDEIYPPIPDHIIDLTSDKPSETPYKNELLNREPTSVSAIQNEILDLPENIEPVLDEVD--EEF-RGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEK-GDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYL---ELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
++W+ IW+ WFDE++PP DH S T + E +P S N+ L + I P+LD+VD E G E L EV +++ M N F L RRGALY+K+G L A D+N AIS+EP L+ AYW RH + L+ N A++DLN I+K +K + A++SRA IY G+ LAI + +Q I+ PDD+E Y +RA+LYE+ E LA+EDY + + A+M H L++ + W++A DFS +L+ P+N A +RG +AKL +++A+ DF +HLDP ++LA++ RGCLLR+ P +A+RD S+S+L+ S EN+ +++YRG+LY +Q+ +A+ DF+ VI ++ + AH+NLGLIY K +K+++ ++ + ADPT I+ Y CRA AY +N + A+KD+ RA+HL PD +++RG M + +A C++ +AE+ LG + VQQA V SFLQ+ +AI L+ A PS ++L LLG TQ+K ++ +A+ SF L L PK P A L +L CY+ E ++ AFS +INP++AEAY+ +G CR+RL + + D NRAL INP YQAYL+RA L+G K Y KAI NC+E L I+P+ ++AYLY+G LK+ +K Y A++D T AI+ID++C LA++NR VC+ ++ Y+ A++DYS VLL+ + + +K INR LV+ EL D NAL D A + QP D + + +G+ H+L L+EA+ ++ L P + A V RGN FMDY S A +D+ S L ++ A + L + Q G F++ W+ FT+A+E +P +GRAIV +QM + A +D+N A++ P S L NRGV+ Q M DK+ AM DY +AI + C +A+FNA +Y +N Q EQA E + + +E DP DE+ +N A+ K+ ES++ + ++ L P SA++YFNRAN+ L++Y+ AE +F L++ PDD + K R D R G A++DY+T+V
Sbjct: 655 QEWVGDIWNTWFDEVFPP-QDH---------SSTKSEPEARQMQPVS-----NKQLKKKKEI-PILDKVDLSEALDEGFTVEDLEMEVAKLTESMIKNTGNNGFDLCRRGALYKKLGLLKQALDDLNAAISLEPHLLDAYWHRHSISLLRNAPNSALDDLNFIIKHNKKHADAFRSRAEIYRMRGETRLAILDYTQVIKNKPDDAENYFRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLLRRILPDVALRDLSVSVLINGSSENLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYMLKMNQSQKAIRRFSNAIKADPTNIKGYVCRARAYHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGLTLVQQAAVQSFLQNDAKAIACLVSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRIRL-QHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEIDSSCSLAYYNRGVCYQVLQE-YKLALRDYSTVLLLPEQKEIEFKVLINRTLVHKELNDHYNALQDLKAAASKQPKDASLFHSLGLYFHRLGQLQEAVEAYSEALRLSPFLLNAYVGRGNAFMDYGHSQGYKQAQRDFLSALHLNPRCSSARIGLAYNLQVFGCFQRVWNQFTVAVEVNPKCWAAYEGRAIVNLQMGNTYAAFQDINNALKCNPHSDQLLTNRGVINQFMGDKVSAMSDYQRAISLNP-TCALAFFNAANLYFYNRQFEQACEYYSRAIELDPSDESPVLNRAISLALLQKIPESLQDFSEALRLCPYSAHIYFNRANLYHSLRKYKAAEREFTQALQLQPDDALLYKLRADVRGHLGLMEEAVKDYRTAV 1705 HSP 2 Score: 141.739 bits (356), Expect = 2.659e-33 Identity = 195/904 (21.57%), Postives = 363/904 (40.15%), Query Frame = 2
Query: 1448 VKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDD--------------------------------SE---AYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGL-YYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRG-CL------------------LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRG---------ILYATTK----QFSEAIVDFEVVICF----NKDMCFA------HVNLGLIYFEKGD---FEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNL-LGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYL--ELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLF---GFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIK---DFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLI---SDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQ 3880
+KN D ENY RR LY K + A +D +I + A L H + ++A++D +L+LK++ A R +A G AI + A+ L P D SE A+ R LY + + + A+ D+ +I++ A + GL Y L + Q Q A + FS+ ++ P+N + ++ R AY + + AL D + +HL P++ + RG CL ++KA ++ ++ L++ + I + IL T+ +F EA+ F+ + F ++C + G+ Y +G+ ++++ + +P Y AY R ++ ++ ++++D NRA+ + P+ Y+ R Y A G A +A +I ++ + + + +L+ Y +A++ L VA S +L G + +K A+ ++ L L P+ + L+ R + EL ++ + A P A ++ G RLG++++ + + AL ++P L AY+ R F G Y +A + L + PRC A R L Y ++ + + FT A++++ C A+ RA+ N + N A QD + L SD L NRG++ +GD +A+ D+ RA ++ P + + + ++A ++R ++ DP ++R + + L +D++ L + Y N + K+K A FT A++ P+ RA V + + A+KD A+ +Q
Sbjct: 836 IKNKPDDAENY--------FRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLLRRILPDVALRDLSVSVLINGSSENLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYMLKMNQSQKAIRRFSNAIKADPTNIKGYVCRARAYHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGLTLVQQAAVQSFLQNDAKAIACLVSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRIRL-QHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEIDSSCSLAYYNRGVCYQVLQEYKLALRDYSTVL--LLPEQK-------EIEFKVLINRTLVHKELNDHYNALQDLKAAASKQPKDASLFHSLGLYFHRLGQLQEAVEAYSEALRLSPFLLNAYVGRGNAFMDYGHSQGYKQAQRDFLSALHLNPRCSSA---RIGLAYNLQVFGCFQRVWNQFTVAVEVNPKCWAAYEGRAI-VNLQMGNTYAAFQDINNALKCNPHSDQL------LTNRGVINQFMGDKVSAMSDYQRAISLNPTCALAFFNAANLYFYNRQFEQACEYYSRAIELDPSDESPVLNRA-ISLALLQKIPESL--QDFSEALRLCPYSAHIYFNRANLYHSLRKYKAAEREFTQALQLQPDDALLYKLRADVRGHLGLMEEAVKDYRTAVELQ 1708 HSP 3 Score: 96.6709 bits (239), Expect = 1.684e-19 Identity = 124/515 (24.08%), Postives = 221/515 (42.91%), Query Frame = 2
Query: 2912 LAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFI------RAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEI---DSY-HL---DALVNL------GFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQ---LEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
L ++ +K P+ AE Y+ + + ++ + D + AIN A +A A + + A+ + + +L EP RA YRG K+ + AI+DF A+ +D LAF++R + + A++D S+ +LI+ + + A++ RGL+Y E Q A+ DF R A +L ++Y++ K+ ++AIR F+ + DP I V R Y++ N A KD L + D Y H+ L N+ FC Q + KKA + T+ + S D +AI C+ ++ A + +I I + L +++ + K ++ + K I + P Y+ G Y+ + L QALE F K +P + L I + + S++ NR++ ++PN Y +RA + Y +A + L+I P + +G + + A+ED ++ I
Sbjct: 830 LDYTQVIKNKPDDAENYFRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLL--RRILPDVALRDLSVSVLINGSSE-NLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYML-----KMNQSQKAIRRFSNAIKADPTNIKGYVCRARA---YHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGL-TLVQQAAVQSFLQNDAKAIACL----VSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRI-RLQHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEI 1327
BLAST of TPR_REGION domain-containing protein vs. Ensembl Cavefish
Match: ttc6 (tetratricopeptide repeat domain 6 [Source:ZFIN;Acc:ZDB-GENE-090429-2]) HSP 1 Score: 786.178 bits (2029), Expect = 0.000e+0 Identity = 427/1070 (39.91%), Postives = 644/1070 (60.19%), Query Frame = 2
Query: 1196 RDWITVIWDQWFDEIYPPIPDHIIDLTSDKPSETPYKNELLNREPTSVSAIQNEILDLPENIEPVLDEVD--EEF-RGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEK-GDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYL---ELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
++W+ IW+ WFDE++PP DH S T + E +P S N+ L + I P+LD+VD E G E L EV +++ M N F L RRGALY+K+G L A D+N AIS+EP L+ AYW RH + L+ N A++DLN I+K +K + A++SRA IY G+ LAI + +Q I+ PDD+E Y +RA+LYE+ E LA+EDY + + A+M H L++ + W++A DFS +L+ P+N A +RG +AKL +++A+ DF +HLDP ++LA++ RGCLLR+ P +A+RD S+S+L+ S EN+ +++YRG+LY +Q+ +A+ DF+ VI ++ + AH+NLGLIY K +K+++ ++ + ADPT I+ Y CRA AY +N + A+KD+ RA+HL PD +++RG M + +A C++ +AE+ LG + VQQA V SFLQ+ +AI L+ A PS ++L LLG TQ+K ++ +A+ SF L L PK P A L +L CY+ E ++ AFS +INP++AEAY+ +G CR+RL + + D NRAL INP YQAYL+RA L+G K Y KAI NC+E L I+P+ ++AYLY+G LK+ +K Y A++D T AI+ID++C LA++NR VC+ ++ Y+ A++DYS VLL+ + + +K INR LV+ EL D NAL D A + QP D + + +G+ H+L L+EA+ ++ L P + A V RGN FMDY S A +D+ S L ++ A + L + Q G F++ W+ FT+A+E +P +GRAIV +QM + A +D+N A++ P S L NRGV+ Q M DK+ AM DY +AI + C +A+FNA +Y +N Q EQA E + + +E DP DE+ +N A+ K+ ES++ + ++ L P SA++YFNRAN+ L++Y+ AE +F L++ PDD + K R D R G A++DY+T+V
Sbjct: 690 QEWVGDIWNTWFDEVFPP-QDH---------SSTKSEPEARQMQPVS-----NKQLKKKKEI-PILDKVDLSEALDEGFTVEDLEMEVAKLTESMIKNTGNNGFDLCRRGALYKKLGLLKQALDDLNAAISLEPHLLDAYWHRHSISLLRNAPNSALDDLNFIIKHNKKHADAFRSRAEIYRMRGETRLAILDYTQVIKNKPDDAENYFRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLLRRILPDVALRDLSVSVLINGSSENLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYMLKMNQSQKAIRRFSNAIKADPTNIKGYVCRARAYHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGLTLVQQAAVQSFLQNDAKAIACLVSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRIRL-QHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEIDSSCSLAYYNRGVCYQVLQE-YKLALRDYSTVLLLPEQKEIEFKVLINRTLVHKELNDHYNALQDLKAAASKQPKDASLFHSLGLYFHRLGQLQEAVEAYSEALRLSPFLLNAYVGRGNAFMDYGHSQGYKQAQRDFLSALHLNPRCSSARIGLAYNLQVFGCFQRVWNQFTVAVEVNPKCWAAYEGRAIVNLQMGNTYAAFQDINNALKCNPHSDQLLTNRGVINQFMGDKVSAMSDYQRAISLNP-TCALAFFNAANLYFYNRQFEQACEYYSRAIELDPSDESPVLNRAISLALLQKIPESLQDFSEALRLCPYSAHIYFNRANLYHSLRKYKAAEREFTQALQLQPDDALLYKLRADVRGHLGLMEEAVKDYRTAV 1740 HSP 2 Score: 141.354 bits (355), Expect = 3.979e-33 Identity = 195/904 (21.57%), Postives = 363/904 (40.15%), Query Frame = 2
Query: 1448 VKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDD--------------------------------SE---AYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGL-YYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRG-CL------------------LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRG---------ILYATTK----QFSEAIVDFEVVICF----NKDMCFA------HVNLGLIYFEKGD---FEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNL-LGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYL--ELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLF---GFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIK---DFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLI---SDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQ 3880
+KN D ENY RR LY K + A +D +I + A L H + ++A++D +L+LK++ A R +A G AI + A+ L P D SE A+ R LY + + + A+ D+ +I++ A + GL Y L + Q Q A + FS+ ++ P+N + ++ R AY + + AL D + +HL P++ + RG CL ++KA ++ ++ L++ + I + IL T+ +F EA+ F+ + F ++C + G+ Y +G+ ++++ + +P Y AY R ++ ++ ++++D NRA+ + P+ Y+ R Y A G A +A +I ++ + + + +L+ Y +A++ L VA S +L G + +K A+ ++ L L P+ + L+ R + EL ++ + A P A ++ G RLG++++ + + AL ++P L AY+ R F G Y +A + L + PRC A R L Y ++ + + FT A++++ C A+ RA+ N + N A QD + L SD L NRG++ +GD +A+ D+ RA ++ P + + + ++A ++R ++ DP ++R + + L +D++ L + Y N + K+K A FT A++ P+ RA V + + A+KD A+ +Q
Sbjct: 871 IKNKPDDAENY--------FRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLLRRILPDVALRDLSVSVLINGSSENLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYMLKMNQSQKAIRRFSNAIKADPTNIKGYVCRARAYHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGLTLVQQAAVQSFLQNDAKAIACLVSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRIRL-QHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEIDSSCSLAYYNRGVCYQVLQEYKLALRDYSTVL--LLPEQK-------EIEFKVLINRTLVHKELNDHYNALQDLKAAASKQPKDASLFHSLGLYFHRLGQLQEAVEAYSEALRLSPFLLNAYVGRGNAFMDYGHSQGYKQAQRDFLSALHLNPRCSSA---RIGLAYNLQVFGCFQRVWNQFTVAVEVNPKCWAAYEGRAI-VNLQMGNTYAAFQDINNALKCNPHSDQL------LTNRGVINQFMGDKVSAMSDYQRAISLNPTCALAFFNAANLYFYNRQFEQACEYYSRAIELDPSDESPVLNRA-ISLALLQKIPESL--QDFSEALRLCPYSAHIYFNRANLYHSLRKYKAAEREFTQALQLQPDDALLYKLRADVRGHLGLMEEAVKDYRTAVELQ 1743 HSP 3 Score: 96.6709 bits (239), Expect = 1.871e-19 Identity = 124/515 (24.08%), Postives = 221/515 (42.91%), Query Frame = 2
Query: 2912 LAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFI------RAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEI---DSY-HL---DALVNL------GFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQ---LEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
L ++ +K P+ AE Y+ + + ++ + D + AIN A +A A + + A+ + + +L EP RA YRG K+ + AI+DF A+ +D LAF++R + + A++D S+ +LI+ + + A++ RGL+Y E Q A+ DF R A +L ++Y++ K+ ++AIR F+ + DP I V R Y++ N A KD L + D Y H+ L N+ FC Q + KKA + T+ + S D +AI C+ ++ A + +I I + L +++ + K ++ + K I + P Y+ G Y+ + L QALE F K +P + L I + + S++ NR++ ++PN Y +RA + Y +A + L+I P + +G + + A+ED ++ I
Sbjct: 865 LDYTQVIKNKPDDAENYFRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLL--RRILPDVALRDLSVSVLINGSSE-NLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYML-----KMNQSQKAIRRFSNAIKADPTNIKGYVCRARA---YHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGL-TLVQQAAVQSFLQNDAKAIACL----VSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRI-RLQHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEI 1362
BLAST of TPR_REGION domain-containing protein vs. Ensembl Cavefish
Match: ttc6 (tetratricopeptide repeat domain 6 [Source:ZFIN;Acc:ZDB-GENE-090429-2]) HSP 1 Score: 786.178 bits (2029), Expect = 0.000e+0 Identity = 427/1070 (39.91%), Postives = 644/1070 (60.19%), Query Frame = 2
Query: 1196 RDWITVIWDQWFDEIYPPIPDHIIDLTSDKPSETPYKNELLNREPTSVSAIQNEILDLPENIEPVLDEVD--EEF-RGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEK-GDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYL---ELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
++W+ IW+ WFDE++PP DH S T + E +P S N+ L + I P+LD+VD E G E L EV +++ M N F L RRGALY+K+G L A D+N AIS+EP L+ AYW RH + L+ N A++DLN I+K +K + A++SRA IY G+ LAI + +Q I+ PDD+E Y +RA+LYE+ E LA+EDY + + A+M H L++ + W++A DFS +L+ P+N A +RG +AKL +++A+ DF +HLDP ++LA++ RGCLLR+ P +A+RD S+S+L+ S EN+ +++YRG+LY +Q+ +A+ DF+ VI ++ + AH+NLGLIY K +K+++ ++ + ADPT I+ Y CRA AY +N + A+KD+ RA+HL PD +++RG M + +A C++ +AE+ LG + VQQA V SFLQ+ +AI L+ A PS ++L LLG TQ+K ++ +A+ SF L L PK P A L +L CY+ E ++ AFS +INP++AEAY+ +G CR+RL + + D NRAL INP YQAYL+RA L+G K Y KAI NC+E L I+P+ ++AYLY+G LK+ +K Y A++D T AI+ID++C LA++NR VC+ ++ Y+ A++DYS VLL+ + + +K INR LV+ EL D NAL D A + QP D + + +G+ H+L L+EA+ ++ L P + A V RGN FMDY S A +D+ S L ++ A + L + Q G F++ W+ FT+A+E +P +GRAIV +QM + A +D+N A++ P S L NRGV+ Q M DK+ AM DY +AI + C +A+FNA +Y +N Q EQA E + + +E DP DE+ +N A+ K+ ES++ + ++ L P SA++YFNRAN+ L++Y+ AE +F L++ PDD + K R D R G A++DY+T+V
Sbjct: 656 QEWVGDIWNTWFDEVFPP-QDH---------SSTKSEPEARQMQPVS-----NKQLKKKKEI-PILDKVDLSEALDEGFTVEDLEMEVAKLTESMIKNTGNNGFDLCRRGALYKKLGLLKQALDDLNAAISLEPHLLDAYWHRHSISLLRNAPNSALDDLNFIIKHNKKHADAFRSRAEIYRMRGETRLAILDYTQVIKNKPDDAENYFRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLLRRILPDVALRDLSVSVLINGSSENLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYMLKMNQSQKAIRRFSNAIKADPTNIKGYVCRARAYHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGLTLVQQAAVQSFLQNDAKAIACLVSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRIRL-QHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEIDSSCSLAYYNRGVCYQVLQE-YKLALRDYSTVLLLPEQKEIEFKVLINRTLVHKELNDHYNALQDLKAAASKQPKDASLFHSLGLYFHRLGQLQEAVEAYSEALRLSPFLLNAYVGRGNAFMDYGHSQGYKQAQRDFLSALHLNPRCSSARIGLAYNLQVFGCFQRVWNQFTVAVEVNPKCWAAYEGRAIVNLQMGNTYAAFQDINNALKCNPHSDQLLTNRGVINQFMGDKVSAMSDYQRAISLNP-TCALAFFNAANLYFYNRQFEQACEYYSRAIELDPSDESPVLNRAISLALLQKIPESLQDFSEALRLCPYSAHIYFNRANLYHSLRKYKAAEREFTQALQLQPDDALLYKLRADVRGHLGLMEEAVKDYRTAV 1706 HSP 2 Score: 142.124 bits (357), Expect = 2.403e-33 Identity = 195/904 (21.57%), Postives = 363/904 (40.15%), Query Frame = 2
Query: 1448 VKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDD--------------------------------SE---AYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGL-YYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRG-CL------------------LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRG---------ILYATTK----QFSEAIVDFEVVICF----NKDMCFA------HVNLGLIYFEKGD---FEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNL-LGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYL--ELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLF---GFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIK---DFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLI---SDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQ 3880
+KN D ENY RR LY K + A +D +I + A L H + ++A++D +L+LK++ A R +A G AI + A+ L P D SE A+ R LY + + + A+ D+ +I++ A + GL Y L + Q Q A + FS+ ++ P+N + ++ R AY + + AL D + +HL P++ + RG CL ++KA ++ ++ L++ + I + IL T+ +F EA+ F+ + F ++C + G+ Y +G+ ++++ + +P Y AY R ++ ++ ++++D NRA+ + P+ Y+ R Y A G A +A +I ++ + + + +L+ Y +A++ L VA S +L G + +K A+ ++ L L P+ + L+ R + EL ++ + A P A ++ G RLG++++ + + AL ++P L AY+ R F G Y +A + L + PRC A R L Y ++ + + FT A++++ C A+ RA+ N + N A QD + L SD L NRG++ +GD +A+ D+ RA ++ P + + + ++A ++R ++ DP ++R + + L +D++ L + Y N + K+K A FT A++ P+ RA V + + A+KD A+ +Q
Sbjct: 837 IKNKPDDAENY--------FRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLLRRILPDVALRDLSVSVLINGSSENLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYMLKMNQSQKAIRRFSNAIKADPTNIKGYVCRARAYHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGLTLVQQAAVQSFLQNDAKAIACLVSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRIRL-QHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEIDSSCSLAYYNRGVCYQVLQEYKLALRDYSTVL--LLPEQK-------EIEFKVLINRTLVHKELNDHYNALQDLKAAASKQPKDASLFHSLGLYFHRLGQLQEAVEAYSEALRLSPFLLNAYVGRGNAFMDYGHSQGYKQAQRDFLSALHLNPRCSSA---RIGLAYNLQVFGCFQRVWNQFTVAVEVNPKCWAAYEGRAI-VNLQMGNTYAAFQDINNALKCNPHSDQL------LTNRGVINQFMGDKVSAMSDYQRAISLNPTCALAFFNAANLYFYNRQFEQACEYYSRAIELDPSDESPVLNRA-ISLALLQKIPESL--QDFSEALRLCPYSAHIYFNRANLYHSLRKYKAAEREFTQALQLQPDDALLYKLRADVRGHLGLMEEAVKDYRTAVELQ 1709 HSP 3 Score: 96.6709 bits (239), Expect = 1.459e-19 Identity = 124/515 (24.08%), Postives = 221/515 (42.91%), Query Frame = 2
Query: 2912 LAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFI------RAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEI---DSY-HL---DALVNL------GFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQ---LEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
L ++ +K P+ AE Y+ + + ++ + D + AIN A +A A + + A+ + + +L EP RA YRG K+ + AI+DF A+ +D LAF++R + + A++D S+ +LI+ + + A++ RGL+Y E Q A+ DF R A +L ++Y++ K+ ++AIR F+ + DP I V R Y++ N A KD L + D Y H+ L N+ FC Q + KKA + T+ + S D +AI C+ ++ A + +I I + L +++ + K ++ + K I + P Y+ G Y+ + L QALE F K +P + L I + + S++ NR++ ++PN Y +RA + Y +A + L+I P + +G + + A+ED ++ I
Sbjct: 831 LDYTQVIKNKPDDAENYFRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLL--RRILPDVALRDLSVSVLINGSSE-NLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYML-----KMNQSQKAIRRFSNAIKADPTNIKGYVCRARA---YHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGL-TLVQQAAVQSFLQNDAKAIACL----VSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRI-RLQHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEI 1328
BLAST of TPR_REGION domain-containing protein vs. Ensembl Cavefish
Match: ttc6 (tetratricopeptide repeat domain 6 [Source:ZFIN;Acc:ZDB-GENE-090429-2]) HSP 1 Score: 785.793 bits (2028), Expect = 0.000e+0 Identity = 427/1070 (39.91%), Postives = 644/1070 (60.19%), Query Frame = 2
Query: 1196 RDWITVIWDQWFDEIYPPIPDHIIDLTSDKPSETPYKNELLNREPTSVSAIQNEILDLPENIEPVLDEVD--EEF-RGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEK-GDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYL---ELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
++W+ IW+ WFDE++PP DH S T + E +P S N+ L + I P+LD+VD E G E L EV +++ M N F L RRGALY+K+G L A D+N AIS+EP L+ AYW RH + L+ N A++DLN I+K +K + A++SRA IY G+ LAI + +Q I+ PDD+E Y +RA+LYE+ E LA+EDY + + A+M H L++ + W++A DFS +L+ P+N A +RG +AKL +++A+ DF +HLDP ++LA++ RGCLLR+ P +A+RD S+S+L+ S EN+ +++YRG+LY +Q+ +A+ DF+ VI ++ + AH+NLGLIY K +K+++ ++ + ADPT I+ Y CRA AY +N + A+KD+ RA+HL PD +++RG M + +A C++ +AE+ LG + VQQA V SFLQ+ +AI L+ A PS ++L LLG TQ+K ++ +A+ SF L L PK P A L +L CY+ E ++ AFS +INP++AEAY+ +G CR+RL + + D NRAL INP YQAYL+RA L+G K Y KAI NC+E L I+P+ ++AYLY+G LK+ +K Y A++D T AI+ID++C LA++NR VC+ ++ Y+ A++DYS VLL+ + + +K INR LV+ EL D NAL D A + QP D + + +G+ H+L L+EA+ ++ L P + A V RGN FMDY S A +D+ S L ++ A + L + Q G F++ W+ FT+A+E +P +GRAIV +QM + A +D+N A++ P S L NRGV+ Q M DK+ AM DY +AI + C +A+FNA +Y +N Q EQA E + + +E DP DE+ +N A+ K+ ES++ + ++ L P SA++YFNRAN+ L++Y+ AE +F L++ PDD + K R D R G A++DY+T+V
Sbjct: 690 QEWVGDIWNTWFDEVFPP-QDH---------SSTKSEPEARQMQPVS-----NKQLKKKKEI-PILDKVDLSEALDEGFTVEDLEMEVAKLTESMIKNTGNNGFDLCRRGALYKKLGLLKQALDDLNAAISLEPHLLDAYWHRHSISLLRNAPNSALDDLNFIIKHNKKHADAFRSRAEIYRMRGETRLAILDYTQVIKNKPDDAENYFRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLLRRILPDVALRDLSVSVLINGSSENLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYMLKMNQSQKAIRRFSNAIKADPTNIKGYVCRARAYHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGLTLVQQAAVQSFLQNDAKAIACLVSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRIRL-QHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEIDSSCSLAYYNRGVCYQVLQE-YKLALRDYSTVLLLPEQKEIEFKVLINRTLVHKELNDHYNALQDLKAAASKQPKDASLFHSLGLYFHRLGQLQEAVEAYSEALRLSPFLLNAYVGRGNAFMDYGHSQGYKQAQRDFLSALHLNPRCSSARIGLAYNLQVFGCFQRVWNQFTVAVEVNPKCWAAYEGRAIVNLQMGNTYAAFQDINNALKCNPHSDQLLTNRGVINQFMGDKVSAMSDYQRAISLNP-TCALAFFNAANLYFYNRQFEQACEYYSRAIELDPSDESPVLNRAISLALLQKIPESLQDFSEALRLCPYSAHIYFNRANLYHSLRKYKAAEREFTQALQLQPDDALLYKLRADVRGHLGLMEEAVKDYRTAV 1740 HSP 2 Score: 142.124 bits (357), Expect = 2.349e-33 Identity = 195/904 (21.57%), Postives = 363/904 (40.15%), Query Frame = 2
Query: 1448 VKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDD--------------------------------SE---AYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGL-YYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRG-CL------------------LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRG---------ILYATTK----QFSEAIVDFEVVICF----NKDMCFA------HVNLGLIYFEKGD---FEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNL-LGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYL--ELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLF---GFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIK---DFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLI---SDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQ 3880
+KN D ENY RR LY K + A +D +I + A L H + ++A++D +L+LK++ A R +A G AI + A+ L P D SE A+ R LY + + + A+ D+ +I++ A + GL Y L + Q Q A + FS+ ++ P+N + ++ R AY + + AL D + +HL P++ + RG CL ++KA ++ ++ L++ + I + IL T+ +F EA+ F+ + F ++C + G+ Y +G+ ++++ + +P Y AY R ++ ++ ++++D NRA+ + P+ Y+ R Y A G A +A +I ++ + + + +L+ Y +A++ L VA S +L G + +K A+ ++ L L P+ + L+ R + EL ++ + A P A ++ G RLG++++ + + AL ++P L AY+ R F G Y +A + L + PRC A R L Y ++ + + FT A++++ C A+ RA+ N + N A QD + L SD L NRG++ +GD +A+ D+ RA ++ P + + + ++A ++R ++ DP ++R + + L +D++ L + Y N + K+K A FT A++ P+ RA V + + A+KD A+ +Q
Sbjct: 871 IKNKPDDAENY--------FRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLLRRILPDVALRDLSVSVLINGSSENLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYMLKMNQSQKAIRRFSNAIKADPTNIKGYVCRARAYHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGLTLVQQAAVQSFLQNDAKAIACLVSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRIRL-QHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEIDSSCSLAYYNRGVCYQVLQEYKLALRDYSTVL--LLPEQK-------EIEFKVLINRTLVHKELNDHYNALQDLKAAASKQPKDASLFHSLGLYFHRLGQLQEAVEAYSEALRLSPFLLNAYVGRGNAFMDYGHSQGYKQAQRDFLSALHLNPRCSSA---RIGLAYNLQVFGCFQRVWNQFTVAVEVNPKCWAAYEGRAI-VNLQMGNTYAAFQDINNALKCNPHSDQL------LTNRGVINQFMGDKVSAMSDYQRAISLNPTCALAFFNAANLYFYNRQFEQACEYYSRAIELDPSDESPVLNRA-ISLALLQKIPESL--QDFSEALRLCPYSAHIYFNRANLYHSLRKYKAAEREFTQALQLQPDDALLYKLRADVRGHLGLMEEAVKDYRTAVELQ 1743 HSP 3 Score: 96.6709 bits (239), Expect = 1.598e-19 Identity = 124/515 (24.08%), Postives = 221/515 (42.91%), Query Frame = 2
Query: 2912 LAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFI------RAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEI---DSY-HL---DALVNL------GFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQ---LEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
L ++ +K P+ AE Y+ + + ++ + D + AIN A +A A + + A+ + + +L EP RA YRG K+ + AI+DF A+ +D LAF++R + + A++D S+ +LI+ + + A++ RGL+Y E Q A+ DF R A +L ++Y++ K+ ++AIR F+ + DP I V R Y++ N A KD L + D Y H+ L N+ FC Q + KKA + T+ + S D +AI C+ ++ A + +I I + L +++ + K ++ + K I + P Y+ G Y+ + L QALE F K +P + L I + + S++ NR++ ++PN Y +RA + Y +A + L+I P + +G + + A+ED ++ I
Sbjct: 865 LDYTQVIKNKPDDAENYFRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLL--RRILPDVALRDLSVSVLINGSSE-NLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYML-----KMNQSQKAIRRFSNAIKADPTNIKGYVCRARA---YHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGL-TLVQQAAVQSFLQNDAKAIACL----VSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRI-RLQHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEI 1362
BLAST of TPR_REGION domain-containing protein vs. Ensembl Cavefish
Match: ttc6 (tetratricopeptide repeat domain 6 [Source:ZFIN;Acc:ZDB-GENE-090429-2]) HSP 1 Score: 760.37 bits (1962), Expect = 0.000e+0 Identity = 413/1032 (40.02%), Postives = 623/1032 (60.37%), Query Frame = 2
Query: 1196 RDWITVIWDQWFDEIYPPIPDHIIDLTSDKPSETPYKNELLNREPTSVSAIQNEILDLPENIEPVLDEVD--EEF-RGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEK-GDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYL---ELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDF 4270
++W+ IW+ WFDE++PP DH S T + E +P S N+ L + I P+LD+VD E G E L EV +++ M N F L RRGALY+K+G L A D+N AIS+EP L+ AYW RH + L+ N A++DLN I+K +K + A++SRA IY G+ LAI + +Q I+ PDD+E Y +RA+LYE+ E LA+EDY + + A+M H L++ + W++A DFS +L+ P+N A +RG +AKL +++A+ DF +HLDP ++LA++ RGCLLR+ P +A+RD S+S+L+ S EN+ +++YRG+LY +Q+ +A+ DF+ VI ++ + AH+NLGLIY K +K+++ ++ + ADPT I+ Y CRA AY +N + A+KD+ RA+HL PD +++RG M + +A C++ +AE+ LG + VQQA V SFLQ+ +AI L+ A PS ++L LLG TQ+K ++ +A+ SF L L PK P A L +L CY+ E ++ AFS +INP++AEAY+ +G CR+RL + + D NRAL INP YQAYL+RA L+G K Y KAI NC+E L I+P+ ++AYLY+G LK+ +K Y A++D T AI+ID++C LA++NR VC+ ++ Y+ A++DYS VLL+ + + +K INR LV+ EL D NAL D A + QP D + + +G+ H+L L+EA+ ++ L P + A V RGN FMDY S A +D+ S L ++ A + L + Q G F++ W+ FT+A+E +P +GRAIV +QM + A +D+N A++ P S L NRGV+ Q M DK+ AM DY +AI + C +A+FNA +Y +N Q EQA E + + +E DP DE+ +N A+ K+ ES++ + ++ L P SA++YFNRAN+ L++Y+ AE +F
Sbjct: 690 QEWVGDIWNTWFDEVFPP-QDH---------SSTKSEPEARQMQPVS-----NKQLKKKKEI-PILDKVDLSEALDEGFTVEDLEMEVAKLTESMIKNTGNNGFDLCRRGALYKKLGLLKQALDDLNAAISLEPHLLDAYWHRHSISLLRNAPNSALDDLNFIIKHNKKHADAFRSRAEIYRMRGETRLAILDYTQVIKNKPDDAENYFRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYHRGCLLRRILPDVALRDLSVSVLINGSSENLAAFLYRGLLYTEQQQWQKAMADFKAVIKIDRTVAAAHINLGLIYMLKMNQSQKAIRRFSNAIKADPTNIKGYVCRARAYHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGLTLVQQAAVQSFLQNDAKAIACLVSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPDYAEAYHQRGLCRIRL-QHSNSVQDFNRALCINPNFYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKKAVEDLTVAIEIDSSCSLAYYNRGVCYQVLQE-YKLALRDYSTVLLLPEQKEIEFKVLINRTLVHKELNDHYNALQDLKAAASKQPKDASLFHSLGLYFHRLGQLQEAVEAYSEALRLSPFLLNAYVGRGNAFMDYGHSQGYKQAQRDFLSALHLNPRCSSARIGLAYNLQVFGCFQRVWNQFTVAVEVNPKCWAAYEGRAIVNLQMGNTYAAFQDINNALKCNPHSDQLLTNRGVINQFMGDKVSAMSDYQRAISLNP-TCALAFFNAANLYFYNRQFEQACEYYSRAIELDPSDESPVLNRAISLALLQKIPESLQDFSEALRLCPYSAHIYFNRANLYHSLRKYKAAEREF 1702 HSP 2 Score: 98.9821 bits (245), Expect = 3.067e-20 Identity = 188/898 (20.94%), Postives = 360/898 (40.09%), Query Frame = 2
Query: 1877 IIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFP-DRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLR----LGKMKQGILDLNRALAINPRLYQAYLARA---------TLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYR------------------------GVLKYKIKAYSLAIKDFTEAI-----KIDANCILA-----FFNRAVCFNAEKKN--YEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNL-KEAIRVFTRCLDHDPKFILAKVSRGNV---FMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAI---EKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGG--LKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+I+ NN + + G Y + + A D ++ + P +A+ HR + AL D + +I + + A+ R + R + E LAI D++ ++++ ++ +Y R LY T + S A+ D+ N + A + L +F + ++ + L +P RA R + ++ +++AI+D A+HL P D FY RG + + + + +R + V + + + A L RG LL T Q ++W+ A+ F ++ + AA++N + L++ +K+ FS +K +P + + Y CR R + +K+ + DL RAL + P ++ R L F QY+ + + ++ ++++L G + K+ + A++ F +A+ K C + ++ VC+ A+ ++ +A++ +S I+ + +AY RGL + L N++ DF RA I PN Y Y+ + K L +AI + L PK + A + +G + +Y A +D +EIDS A N G C Q ++K A ++ + E+ + L R +V +++D AL+DL A QP+ + L+ + G+ + + A++ Y++A+ + L + NA Y H+ +QA F + +P + + LA + ++ ++P Y RA V + A D + L+ P +L RG GD + A+ DY+ ++ +
Sbjct: 768 MIKNTGNNGFDLCRRGALYKKLGLLKQALDDLNAAISLEPHLLDAYWHRHSISLLRNAPNSALDDLNFIIKHNKKHADAFRSRAEIYRMRGETRLAILDYT--QVIKNKPDDAENYFRRADLYEKTNEISLAMEDYAKTFAINLERTDALMAHALHHFHTSVWRVALDDFSLLLKQEPANARARTYRGRTFAKLGLFKEAIEDFCLAVHLDPRDWLAFYH-RG----CLLRRILPDVALRDLS---------------VSVLINGSSENLAAFLY--RG--------LLYTEQ---QQWQKAMADFKAVIKIDRTV--------AAAHINLGLIY-MLKMNQSQKAIRRFSNAIKADPTNIKGYV----CRARAYHNVNDLKRALKDLTRALHLRPDDQYLHIMRGQCLCNMEQTALATFCIQYSAEMKKALGLTLVQQAAVQSFLQNDAKAIACLVSAANSCPSPSILILLGKTQLKVHKFMEAVESFKKALSFLNPKKTNICNVPEAPELYYLTGVCYMAQGEDSLLPQALEAFSKATRINPD---YAEAYHQRGLCRIRLQH-SNSVQDFNRALCINPN-FYQAYLSRAALYGAKGLYNKAIFNCSEALKIQPKNVKAYLYKGALKFYLKEYKK------AVEDLTVAIEIDSSCSLAYYNRGVCYQVLQEYKLALRDYSTVLLLPEQKEIEFKVLINRTLVHKELNDHYNALQDLKAAASKQPKDASLFHSLGLYFHRLGQLQEAVEAYSEALRLSPFLLNAYVGRGNAFMDYGHSQGYKQAQRDFLSALHLNPRCSSARIGLAYNLQVFGCFQRVWNQFTVAVEVNPKCWAAYEGRAIVNLQMGNTYAAFQDINNALKCNPHSDQLLTNRGVINQFMGDKVSAMSDYQRAISL 1606
BLAST of TPR_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: TTC6 (tetratricopeptide repeat domain 6 [Source:HGNC Symbol;Acc:HGNC:19739]) HSP 1 Score: 449.899 bits (1156), Expect = 8.700e-143 Identity = 239/594 (40.24%), Postives = 352/594 (59.26%), Query Frame = 2
Query: 2615 LGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQ-YKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNA-EKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
LG +QQA++ SFL+ + QAI L +P V L LLG+ QMKA+++++A SF L N+ +P AN+ FL+ C +E N+K++ AFSA + I P H EA Y +G CRLRL + G+LD+N+ LA+NP QAYL RA +G K ++TKAI+NCNEVL I+P C+RA+LYRG LKY IKAY LA++D + AI +D +C LA +NRA+C+ + + +A++DYS + L+ L K NRGL+Y + GD QNA DF A I P D +L +G+C+H+L +KEA+ F DP ++ A V RGN M+Y + A +DY L ++ A VNL + QA G+F+KAW+ FT AIE +GRA+V +QM+ AL+D+N A+++ + +L NRG ++Q D + AM+DY +A I+ +AY+NA VY+H QL QAL+ + + VE DP+DE +N A+V ++ ++ +LSP ++Y+YFNRAN+ L +Y+ AE D+ L + P D R + R K G+ A+ DY+ +V I
Sbjct: 4 LGLCSMQQAIIQSFLKDHQQAIACLAGMCSMQPQVTTLALLGSIQMKAEQFQEAKMSFEQALHLSNSVNKDQQPADAARANIYFLLGLCLIEQSNFKEALKAFSAVLHIVPKHQEALYKRGICRLRL-QDSSGLLDINQTLALNPHHIQAYLTRAAYYGMKGRFTKAIMNCNEVLKIQPSCVRAFLYRGSLKYYIKAYKLAVEDLSSAIYLDGSCSLALYNRAICYQELHETDKMQAVKDYSTIALLGKQNDLCRKVMTNRGLLYFDRGDYQNAQQDFYAASKISPTDPKLLQALGICYHRLGRVKEAVAAFGEATKADPFYVSAYVGRGNALMNYGHAPGTRAAQRDYLRALRLNPLSAHARVNLAYSLQANGRFQKAWNHFTTAIELDTRCAEAFEGRAVVNLQMNSTFAALQDINAAVKLGKSAEVL-TNRGAIHQCSGDVVSAMRDY-QAAIVADPNYALAYYNAANVYLHGRQLTQALDYYDRVVELDPMDECAILNRAIVRSLSGDATGALADFCKAATLSPQTSYIYFNRANLHSMLGQYKRAEADYTEALTLQPHDAVTYLCRAEVRGKLGEKEDAISDYRRAVEI 594 HSP 2 Score: 91.6633 bits (226), Expect = 5.210e-19 Identity = 120/507 (23.67%), Postives = 195/507 (38.46%), Query Frame = 2
Query: 1559 DINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEG--RLALEDYNQIIRLQPNNCL---AMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHL------FPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFT-FC-LEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAI 3040
DIN +++ P I AY R + + + AI + N +LK + V A+ R + LA+ +LS AI L S A RA Y++ E A++DY+ I L N L M GL Y + +Q A +DF + + P++ + G Y +L + ++A+ F DP AY RG L M+Y + A + + A+ N A VNL G F+K+ + T+ + D A+ RA QMN A++DIN A+ L +R + GD AM + A + A +N + + L +YD+ ++ A+LN + DA + FC L P+ Y + F A + L YK+++ ++ + + P+ A Y + R +LG+ + I D RA+ I
Sbjct: 138 DINQTLALNPHHIQAYLTRAAYYGMKGRFTKAIMNCNEVLKIQPSCVRAFLYRGSLKYYIKAYKLAVEDLSSAIYLDGSCSLALYNRAICYQELHETDKMQAVKDYSTIALLGKQNDLCRKVMTNRGLLYFDRGDYQNAQQDFYAASKISPTDPKLLQALGICYHRLGRVKEAVAAFGEATKADPFYVSAYVGRGNAL-------------------------MNYGHAPGTRAAQRDYLRALR-------LNPLSAHARVNLAYSLQANGRFQKAWNHFTTAIELDTRCAEAFEGRAVVNLQMNSTFAALQDINAAVKLGKSAEVLTNRGAIHQCSGDVVSAMRDYQAAIVADPNYALAYYNAANVYLHGRQLTQALDYYDRVVE-----LDPMDECAILNRAIVRSLSG----DATGALADFCKAATLSPQTSY---------IYFNRANLHSMLGQYKRAEADYTEALTLQPHDAVTYLCRAEVRGKLGEKEDAISDYRRAVEI 594 HSP 3 Score: 74.3294 bits (181), Expect = 1.392e-13 Identity = 137/637 (21.51%), Postives = 244/637 (38.30%), Query Frame = 2
Query: 1859 LEDYNQII-------RLQPN-NCLAMMKHGLYYLNIEQWQLAAKDFSSVLR--------HYPSNT---EAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRG-CLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKME-MAAICVRQAAEISHNLGQSPV-QQALVHSFLQHYDQ-----AIDALLVATRGKPS-VALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAAN--LNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDS 3679
L+D+ Q I +QP LA++ G + EQ+Q A F L P++ + G + +++AL FSAV+H+ P + A +KRG C LR Q S ++D + N A++ Y KG F K++ L P+ +RA+ R + + Y+ A++D++ AI+L S R Y + + + M A V+ + I+ Q+ + ++ + + L ++D+ A A++ P+ LL LG + R K+A+ +F E K Y G N +N Y + +Q + +++NP A A + + G+ ++ A+ ++ R +A+ RA + N A+ + N + + + RG + A++D+ AI D N LA++N A + + +A+ Y V+ + + A +NR +V GD AL DF +A + P Y+ + H L K A +T L P + + R V ++ A DY +EI +
Sbjct: 18 LKDHQQAIACLAGMCSMQPQVTTLALL--GSIQMKAEQFQEAKMSFEQALHLSNSVNKDQQPADAARANIYFLLGLCLIEQSNFKEALKAFSAVLHIVPKHQEALYKRGICRLR-------------------------------------LQDSSGLLDINQTLALNPHHIQAYLTRAAYYGMKGRFTKAIMNCNEVLKIQPSCVRAFLYRGSLKYYIKAYKLAVEDLSSAIYLDGSCSLALYNRAICYQELHETDKMQA--VKDYSTIALLGKQNDLCRKVMTNRGLLYFDRGDYQNAQQDFYAASKISPTDPKLLQALGICYHRLGRVKEAVAAFG---EATKADPFYVSAYVGRGNALMN------YGHAPGTRAAQRDYLRALRLNPLSAHARVNLAYSLQANGRFQKAWNHFTTAIELDTRCAEAFEGRAVVNLQMNSTFAALQDINAAVKL-GKSAEVLTNRGAIHQCSGDVVSAMRDYQAAIVADPNYALAYYNAANVY-LHGRQLTQALDYYDRVVELDP---MDECAILNRAIVRSLSGDATGALADFCKAATLSPQTSYIYFNRANLHSMLGQYKRAEADYTEALTLQPHDAVTYLCRAEV---RGKLGEKEDAISDYRRAVEIQT 596 HSP 4 Score: 63.5438 bits (153), Expect = 2.361e-10 Identity = 39/142 (27.46%), Postives = 80/142 (56.34%), Query Frame = 2
Query: 1490 NAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMM 1915
+A +L+ RGA+++ G +V+A +D AI +P+ +AY+ ++L ++ A++ + +++ D A +RA + + +GD + A+++ +A LSP S Y RA L+ G+ + A DY + + LQP++ + +
Sbjct: 428 SAEVLTNRGAIHQCSGDVVSAMRDYQAAIVADPNYALAYYNAANVYLHGRQLTQALDYYDRVVELDPMDECAILNRAIVRSLSGDATGALADFCKAATLSPQTSYIYFNRANLHSMLGQYKRAEADYTEALTLQPHDAVTYL 569 HSP 5 Score: 62.7734 bits (151), Expect = 4.805e-10 Identity = 45/194 (23.20%), Postives = 82/194 (42.27%), Query Frame = 2
Query: 1511 RGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHL 2092
R + +M AA +DIN A+ + + R +H + A+ D + D NY LAY + A +Y ++ A+ + + L P D A RA + +G+ AL D+ + L P + + Q++ A D++ L P + +L R KL + +DA++D+ + +
Sbjct: 402 RAVVNLQMNSTFAALQDINAAVKLGKSAEV-LTNRGAIHQCSGDVVSAMRDYQAAIVADPNYALAYYNAANVYLHGRQLTQALDYYDRVVELDPMDECAILNRAIVRSLSGDATGALADFCKAATLSPQTSYIYFNRANLHSMLGQYKRAEADYTEALTLQPHDAVTYLCRAEVRGKLGEKEDAISDYRRAVEI 594
BLAST of TPR_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ogt.1 (O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9631]) HSP 1 Score: 85.1149 bits (209), Expect = 9.327e-17 Identity = 111/483 (22.98%), Postives = 192/483 (39.75%), Query Frame = 2
Query: 2840 PGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKK------NYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
P + L++ + + + +S + +K NP AEAY + G G++ + + A+ + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FN++ + ++EKA+ L AYIN G V E A+ ++RA ++ N V + +++ + AI + R ++ P F A + N + + A + YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I +LE+ NR S+ P+ + LY
Sbjct: 53 PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVFKERGQLAEALEHYRHAVRLKPDFIDGYINLAAALVAAGDLEGAVQAYVTALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFSVAWSNLGCVFNSQGEIWLAIHHFEKAVSLDPNFL----------DAYINLGNVLKEARIFDRAVAAYLRALSLNHNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGNIAE---AEECYNTALHLCPNHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQDALLHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAISSYRTALKLKPDFPDAYCNLAHCLQIICDWTDYDERMKKLVQIVAEQLEK-----NRLPSVHPHHSMLY 514 HSP 2 Score: 82.8037 bits (203), Expect = 4.403e-16 Identity = 101/432 (23.38%), Postives = 175/432 (40.51%), Query Frame = 2
Query: 3101 YTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDY-SIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCP---IAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
Y A +C ++ EP L + ++ + + T AIK + A+ N F E+ +A++ Y V L D + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF NS LA + + +D LDA +NLG + F +A + A+ + N A V + ++ A+ AI +QP Y N + + A + YN A+ + CP + N + +E+A+ +RK +E P A NLA V Q KL++++ + +I +SP A Y N N L ++Q Q A + ++I P +G+ A+ Y+T++
Sbjct: 38 YEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVFK-ERGQLAEALEHYRHAVRLKPDFI----DGYINLAAALVAAGDLEGAVQAYVTALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFSVAWSNLGCVF---NSQGEIWLAIHHFEKAVSLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLNHNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGNIAEAEECYNTALHL----CPNHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQDALLHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAISSYRTAL 457 HSP 3 Score: 80.1073 bits (196), Expect = 3.069e-15 Identity = 91/418 (21.77%), Postives = 177/418 (42.34%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
AI+ +P +EAYS ++++ G+ ALE Y +RL+P+ Y+N+ +AA D ++ Y + N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + N + H NL +Y+E+G + ++ + P + AY A A + +A + N A+HL P+ ++ + G +E A R+A E+ NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C
Sbjct: 82 AIKQNPMLAEAYSNLGNVFKERGQLAEALEHYRHAVRLKPDFIDG-------YINLAAALVAAGDLEGAVQAYVTALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFSVAWSNLGCVFNSQGEIWLAIHHFEKAVSLDPNFLD--AYINLGNVLKEARIFDRAVAAYLRALSLNHNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGNIAEAEECYNTALHLCPNHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQDALLHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAISSYRTALKLKPDFPDAYCNLAHC 473 HSP 4 Score: 64.6994 bits (156), Expect = 1.786e-10 Identity = 76/341 (22.29%), Postives = 137/341 (40.18%), Query Frame = 2
Query: 3374 KAYINRGLVYLELGDVQNALHDFIRAQAIQPN--DLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+AY N G V+ E G + AL + A ++P+ D Y+ + +L+ A++ + L ++P + GN+ + + A Y +E A NLG +QG+ A F A+ PN V + + A+ A+ + ++++ N VY +A+ Y +AI + P AY N + +A EC+ + P NLA + Q +EE++ +++ + P A + N A+VL + Q+A L + +RI+P G+ + D GAL+ Y ++ I
Sbjct: 91 EAYSNLGNVFKERGQLAEALEHYRHAVRLKPDFIDGYINLAAALV--AAGDLEGAVQAYVTALQYNPDLYCVRSDLGNLL---KALGRLEEAKACYLKAIETQPNFSVAWSNLGCVFNSQGEIWLAIHHFEKAVSLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLNHNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP-NFPDAYCNLANALKEKGNIAEAEECYNTALHLCPNHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQDALLHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI 425 HSP 5 Score: 55.8398 bits (133), Expect = 7.654e-8 Identity = 78/369 (21.14%), Postives = 136/369 (36.86%), Query Frame = 2
Query: 1505 SRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL--AAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM----NKYEDAIKDI----------NRAIHLFPDRSNFYMLRGDFYLAMGK 2563
S G ++ G + A A+S++P+ + AY + A+ L + N+ + + + A +Y G I LAI +AI L P+ +AY A ++ G A E YN + L PN+ ++ + L + EQ + A + + L +P A + + + + QDAL + I + P AY G L++ + +G L T+ I N AH NL I+ + G+ +++ + L P + AY C Q+ Y++ +K + NR + P S Y L F A+ +
Sbjct: 196 SNLGCVFNSQGEIWLAIHHFEKAVSLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLNHNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGNIAEAEECYNTALHLCPNHADSL--NNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQDALLHYKEAIRISPTFADAYSNMGNTLKEMQD------------------------VQGALQCYTR-----------AIQINPAFADAHSNLASIHKDSGNIPEAISSYRTALKLKPDFPDAY-CNLAHCLQIICDWTDYDERMKKLVQIVAEQLEKNRLPSVHPHHSMLYPLSHAFRRAIAE 526
BLAST of TPR_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: bbs4 (Bardet-Biedl syndrome 4 [Source:ZFIN;Acc:ZDB-GENE-060126-2]) HSP 1 Score: 51.2174 bits (121), Expect = 1.397e-6 Identity = 65/293 (22.18%), Postives = 117/293 (39.93%), Query Frame = 2
Query: 3371 YKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFM---DYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDL 4240
Y Y+ + L++ G +Q +L F + P + L V L K AI V+ + + ++G +M DY + A + NS L+ + L + V LG +G ++A +++ AIE P + L ++ +QM A + L A+ P + + G + Q D +A+ Y A + P + N + + A+ C ++ P D NL LV++ + + +++ +ISL P LY A L +L
Sbjct: 57 YAVYV-QALIFRLEGKIQESLELFQTCAILNPQNAENLKQVARSLFLLGKHKAAIEVYNEAAKMNERDWEISHNQGVCYMYLKDY------EKAKECLNSALQCSRHDLTSGV-LGRVHLLEGDAERAIEVYRRAIEHSPENTELLTTLGLLYLQMGSYQRAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVA-AHSAPESPPLWNNIAMCFFGKKKYVAAISCLKRAHYLAPFDGKVLYNLGLVHLTMQQHASAFHFLSAAISLMPRMGELYMLLAVALNNL 340
BLAST of TPR_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ift88 (intraflagellar transport 88 homolog [Source:ZFIN;Acc:ZDB-GENE-030131-574]) HSP 1 Score: 50.8322 bits (120), Expect = 2.238e-6 Identity = 79/385 (20.52%), Postives = 151/385 (39.22%), Query Frame = 2
Query: 3296 EKKNYEKAIQDYSIVL--LISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCL---------------DHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLD-GRAIVCMQMSDLNGALKDLN----EAIRIQPQSSM----LYINRGVVYQLMR--DKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALE 4366
++KN+ KAI+ Y + L + S + K N G+ +L +G A+ F + P DL + + +C+ L + R F R + + DP L + N + R +A + + ++ + ++ G+ W + T+ ++ L+ +AI+ +++ D + A++ L + R++ ++ L+ R V Q R D MA YN P A N G EQA + +R+ + +D NL LV+ +L+++++ + S+ N + + A++ L+ +A + + P DPH L GD GD AL+
Sbjct: 82 KQKNFPKAIKFYRMALDQVPSSQREMRMKIMQNIGVAFLRVGHYTEAVSAFEHIMSESP-DLRAAFNLTLCYFALGEHERIKRAFQRLVAVPLGVGDEDRYTPHNDDPHTNLVIDAIKNDMLRQMERERRTMAERFIMTAAKLIAPAIEETFVAGY----------DWCVETVKASQYVELANDLEINKAIMYLKLKDFDQAVEALKMFEKKDTRVKSAAATNLAFLFFLRNDVAQAERYADAAMAADRYN----------PQALVNKGNCLFLGGSAEQAADYYREALRNDASCTEALYNLGLVHKHLGRLQDALDCFLKLHSILRNHPPVMHHIASIYEALEEAGQAAEWLLQLVTVVPTDPHALARLGDVYDADGDKSQALQ 445
BLAST of TPR_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007591.1 (pep scaffold:Pmarinus_7.0:GL480573:24572:27393:-1 gene:ENSPMAG00000006852.1 transcript:ENSPMAT00000007591.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 49.2914 bits (116), Expect = 5.258e-6 Identity = 45/166 (27.11%), Postives = 69/166 (41.57%), Query Frame = 2
Query: 3809 AIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNK---LEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPD 4297
+I+ S L A +AI ++P + YI+RG + M+ A Y KA+ + G + ++N V+I Q AL F + + P N AL+ LEE+ + R L P+ YFN V D+ R EAE + + PD
Sbjct: 22 SIIRTNESRLQEADSLYRQAIAMRPDFTQAYISRGELLLKMQRLPEARAAYEKAVALDGDNADL-WYNLAIVHIELRQPRDALAHFERALALKPAHRLALFNSALLIQETGASELLEEAHGRLLRYAELEPSDEKAYFNLGMVATDMGRADEAERWLRRAVALRPD 186
BLAST of TPR_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO40344 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7J9]) HSP 1 Score: 749.969 bits (1935), Expect = 0.000e+0 Identity = 397/919 (43.20%), Postives = 589/919 (64.09%), Query Frame = 2
Query: 1502 LSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEK-GDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQE 4255
L RRGA++RK+G L A D+N AI +E L+ AYW RHLL+L+ N + A++DL I+K + AY+SRA +Y GD ++AI N SQAI+L+P+D E Y +RA +++ G+ LALEDY RL P+ AM + G+Y N E W A DF+ +L P ++ A+ +RGT +AK+ Q+ AL D +A +H +P+N +A+++RGC+LRK P A++DFS+SLLL+ SEEN+M++M+RGILY K++ +AI DFE I + + A+VN+GLIY K +++K+++ TS + DPTY+RA CRAEA+ +M ++AI D RAIH+ PD S+++M RG L K+++A+ V+QAA+++ LG S QQA+VHSFL+++DQAID L ATR KPS + LLG T MKAKR++DAI+SF +E L P N P P AA + FL+ C E+ N + A++ +K+NP++AEA+Y +G +++L K G+ D NRALAINP+L+QA+L+RA +G K +Y+K I++CNE + ++P+ +RAYLYRG LKY IKA+ LA+KD TEA+ ID C LA+FNRAVC + E K ++KA+ DY V+L+ +L K NRGL+YLE+GD++NAL DF A + + + + +G+C+HKL L+EA+ + L DP F+ A RGN MD+ L +DY L +D L A VNL + Q +GKF+ AW+ F+ AI + L+GRA++ +QM + GA D+NEA++I + +L NRGVV Q M D + A++DY AI + ++Y+NAG VY Q +QAL F K + DE+ +N A+ + + +Y +I L P+ A Y+N NV F +++++
Sbjct: 3 LCRRGAIHRKVGELKKAWDDLNKAIELENMLLDAYWHRHLLYLLQNNKKAALDDLTFIIKHSSSQARAYRSRAELYRQEGDATMAIVNYSQAIKLNPNDVETYYQRAAMFKMRGDMLLALEDYKIASRLLPSKTEAMFEIGMYRFNNENWTGAVNDFTEILEQDPQDSRAYTYRGTVFAKMGQFSKALPDLAAGVHYNPDNAVAFYQRGCILRKIHPRRALQDFSVSLLLDDSEENVMAFMHRGILYTDLKRWEDAIPDFEAAIRLDPSLASAYVNIGLIYIIKHSNYQKAIRQYTSAIRVDPTYVRALICRAEAFQKMGMLQEAILDYARAIHMRPDVSDYHMARGKLLLEQKKLDLASFHVKQAAQLNQGLGASATQQAVVHSFLKNFDQAIDVLERATRVKPSAQIFVLLGKTNMKAKRFEDAISSFLKAIEILTPWNSRNPMPLEAAGVYFLIGMCQSEVHNDSGALDAYNEAIKVNPDYAEAFYQRGLTKMKLSHTK-GVHDFNRALAINPKLFQAFLSRAAYYGMKGRYSKGIMSCNEAIKLQPQSVRAYLYRGALKYHIKAFGLAVKDLTEAVAIDCRCSLAYFNRAVCHH-EMKYFQKALMDYGTVMLLETNPNL--KVLQNRGLLYLEIGDIENALEDFKAAAKVSTLNPKIRHTLGLCYHKLNKLEEAVAAYDDALKIDPFFVEAYNGRGNALMDFGHEQGNVLGRRDYLKALHLDPLCLSARVNLAYNLQVEGKFQAAWNQFSAAIAIDSTCQAALEGRAVINLQMGNTFGAFVDMNEALKISKTAELLN-NRGVVQQYMGDYVNAVRDYQAAIRLEP-SYALSYYNAGNVYFRQRQFKQALSYFNKALSWIGDDESAVLNRAITKYMGDYVNAVRDY-QAAIRLEPSYALSYYNAGNVYFRQRQFKQ 914 HSP 2 Score: 126.331 bits (316), Expect = 2.962e-29 Identity = 186/909 (20.46%), Postives = 350/909 (38.50%), Query Frame = 2
Query: 1814 KRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYL-ELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLF---------------------GFKNQYTKAIL------NCNEVLSIEPRCLRA------YLYRGVLKYKIKAYSLAIKDFTEAIKI----------DANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKN-LKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIF--TMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFR----KTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSV 4384
+R ++ + GE + A +D N+ I L+ A L YL + A D + +++H S A+ R Y + A+ ++S I L+PN+ Y++R + + + + LA+ D+ I+ L S+ M FE+ G+ F ++ +V T L DP RAY R + +M ++ A+ D+ +H PD + + RG C+ L + ++AL Q L+ + +V G KRW+DAI F + P A+ + Y+ + NY+K+ +++ ++++P + A + ++G +++ ILD RA+ + P + ++AR L G T+ + N ++ + + R R ++ G K K + AI F +AI+I +F +C +E N A+ Y+ + ++ + +A+ RGL ++L + +HDF RA AI P L+ ++ ++ +K + I + P+ + A + RG + + LA KD + ID A N C F+KA + M +E +PN + L R ++ +++ D+ AL+D A ++ + + G+ Y + A+ Y+ A+ I + +N + +F EQ R K + DPL + VNLA + K + + + +I++ RA + + A +D L+I+ +L RG + GD + A+ DY+ ++
Sbjct: 5 RRGAIHRKVGELKKAWDDLNKAIELENMLLDAYWHRHLLYLLQNNKKAALDDLTFIIKHSSSQARAYRSRAELYRQEGDATMAIVNYSQAIKLNPNDVETYYQRAAMFKMRGDMLLALEDYKIASRLLPSKTEAM---------------------FEI---------------GMYRFNNENWTGAVNDFTEILEQDPQDSRAYTYRGTVFAKMGQFSKALPDLAAGVHYNPDNAVAFYQRG--------------CI---------LRKIHPRRAL---------QDFSVSLLLDDSEENVMAFMHRGILYTDLKRWEDAIPDFEAAIR----------LDPSLASAYVNIGLIYIIKHSNYQKAIRQYTSAIRVDPTYVRALICRAEAFQKMGMLQEAILDYARAIHMRPDVSDYHMARGKLLLEQKKLDLASFHVKQAAQLNQGLGASATQQAVVHSFLKNFDQAIDVLERATRVKPSAQIFVLLGKTNMKAKRFEDAISSFLKAIEILTPWNSRNPMPLEAAGVYFLIGMC-QSEVHNDSGALDAYNEAIKVNPD---YAEAFYQRGLTKMKLSHTK-GVHDFNRALAINPK-LFQAFLSRAAYYGMKGRYSKGIMSCNEAIKLQPQSVRAYLYRGALKYHIKAFG---LAVKDLTEAVAIDCRCSLAYFNRAVCHHEMKYFQKALMDYGTVMLLETNPNL-KVLQNRGLLYLEIGDIENALEDFKAAAKVSTLNPKIRHTLGLCYHKLNKLEEAVAAYDDALKIDPF--FVEAYNGRGNALMDFGHEQGNVLGRRDYLKALHLDPLCLSARVNLAYNLQVEGKFQAAWNQFSAAIAIDSTCQAALEGRAVINLQMGNTFGAFVDMNEALKISK-TAELLNNRGVVQQYMGDYVNAVRDYQAAI 822 HSP 3 Score: 116.701 bits (291), Expect = 3.324e-26 Identity = 123/568 (21.65%), Postives = 243/568 (42.78%), Query Frame = 2
Query: 2918 FSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQ-YTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHH-KLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVF----------MDYNSSNSRDLAAKDYNSV----------LEIDSYHLD--ALVNLGFCRQAQGK---------FKKAWDIFTMAIEKHP-----------------------------------NSERPLDGRA-----IVCMQMSDLN---GALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPD-DPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+S +K+NPN E YY + G M + D A + P +A + ++ F N+ +T A+ + E+L +P+ RAY YRG + K+ +S A+ D + + + +AF+ R K + +A+QD+S+ LL+ D+ + A+++RG++Y +L ++A+ DF A + P+ +G+ + K N ++AIR +T + DP ++ A + R F +DY + DY+ L++ S+H+ A +N G A + F +A D+ A P NS P+ A ++ M S+++ GAL NEAI++ P + + RG+ ++ + D+N+A+ I K A+ + Y + + + + ++ P ++ + +++ + ++++ + YFNRA +++ +Q+A +D+ + + + + + VL+ RG + GD ALED+K + +
Sbjct: 91 YSQAIKLNPNDVETYYQRAAMFKMRGDMLLALEDYKIASRLLPSKTEA-MFEIGMYRFNNENWTGAVNDFTEILEQDPQDSRAYTYRGTVFAKMGQFSKALPDLAAGVHYNPDNAVAFYQRGCIL--RKIHPRRALQDFSVSLLLDDSEE-NVMAFMHRGILYTDLKRWEDAIPDFEAAIRLDPSLASAYVNIGLIYIIKHSNYQKAIRQYTSAIRVDPTYVRALICRAEAFQKMGMLQEAILDYARAIHMRPDVSDYHMARGKLLLEQKKLDLASFHVKQAAQLNQGLGASATQQAVVHSFLKNFDQAIDVLERATRVKPSAQIFVLLGKTNMKAKRFEDAISSFLKAIEILTPWNSRNPMPLEAAGVYFLIGMCQSEVHNDSGALDAYNEAIKVNPDYAEAFYQRGLT-KMKLSHTKGVHDFNRALAINP-KLFQAFLSRAAYYGMKGRYSKGIMSCNEAIKLQPQSVRAYLYRGALKYHIKAFGLAVKDLTEAVAIDCRCSLAYFNRAVCHHEMKYFQKALMDYGTVMLLETNPNLKVLQNRGLLYLEIGDIENALEDFKAAAKV 652 HSP 4 Score: 51.9878 bits (123), Expect = 1.870e-6 Identity = 61/259 (23.55%), Postives = 104/259 (40.15%), Query Frame = 2
Query: 1514 GALYRKMGYLVAASKDINDAISIEPDLIIAYWER---------------------HLLHL----------------VCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRG-TAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFS 2176
G Y K+ L A +DA+ I+P + AY R LHL V K Q A + + D A + RA I G+ A ++++A+++S +E + R + + G+ A+ DY IRL+P+ L+ G Y Q++ A F+ L + A L+R T Y + + +A+ D+ A I L+P+ L+Y+ G + + + +R S
Sbjct: 664 GLCYHKLNKLEEAVAAYDDALKIDPFFVEAYNGRGNALMDFGHEQGNVLGRRDYLKALHLDPLCLSARVNLAYNLQVEGKFQAAWNQFSAAIAIDSTCQAALEGRAVINLQMGNTFGAFVDMNEALKISKT-AELLNNRGVVQQYMGDYVNAVRDYQAAIRLEPSYALSYYNAGNVYFRQRQFKQALSYFNKALSWIGDDESAVLNRAITKY--MGDYVNAVRDYQAAIRLEPSYALSYYNAGNVYFRQRQFKQVRRSS 919
BLAST of TPR_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO47073 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN48]) HSP 1 Score: 97.0561 bits (240), Expect = 3.405e-20 Identity = 113/483 (23.40%), Postives = 198/483 (40.99%), Query Frame = 2
Query: 2840 PGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKK------NYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLY 4210
P + L++ + + + +S + +K NP AEAY + G G++K + + A+ + P Y+ A A+ L P C+R+ L G L + A + +AI+ + +A+ N FNA+ + ++EKA+Q L AYIN G V E A+ ++RA + PN V + +++ + A+ + R ++ P F A + N + + A + YN+ L++ H D+L NL ++ QGK +++ ++ A+E P A V Q L AL EAIRI P + + N G + + M+D A++ Y++AI I A+ N V+ + + +A++ +R ++ P + NLA LV I +LE NR S+ P+ + LY
Sbjct: 48 PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVFKERGQLKDALANYRHAVKLKPDFIDGYINLAAALVAAGDLEGAVHAYATALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPSFAVAWSNLGCVFNAQGEIWLAIHHFEKAVQLDPNFL----------DAYINLGNVLKEARIFDRAVAAYLRALNLSPNHAVVHGNLACVYYEQGLIDLAVDTYRRAIELQPNFPDAYCNLANALKEQGKVSE---AEECYNTALQLSPTHADSLNNLANIKREQGKIEESIRLYCKALEIFPEFAAAHSNLASVLQQQGKLQEALLHYKEAIRIHPTFADAFSNMGNLLKEMQDIQGAIQCYSRAIQINPAFAD-AHSNLASVHKDSGNIPEAIQSYRTALKLKPSFPDAYCNLAHCLQIICDWTDYDNRMKKLVNIVAEQLEH-----NRLPSVHPHHSMLY 509 HSP 2 Score: 80.4925 bits (197), Expect = 4.291e-15 Identity = 98/431 (22.74%), Postives = 165/431 (38.28%), Query Frame = 2
Query: 3101 YTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDY-SIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
Y +A C ++ EP L + ++ + + T AIK + A+ N F E+ + A+ +Y V L D + YIN + GD++ A+H + A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + +++D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP P AY N ++ +A EC+ ++ P NLA + Q K+EESI +++ + P A + N A+VL + QEA L + +RI P G+ + D GA++ Y ++ I
Sbjct: 33 YDRAEQICMQLWRREPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVFK-ERGQLKDALANYRHAVKLKPDFI----DGYINLAAALVAAGDLEGAVHAYATALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPSFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVQLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALNLSPNHAVVHGNLACVYYEQGLIDLAVDTYRRAIELQP-----------------------------------NFPDAYCNLANALKEQGKVSEAEECYNTALQLSPTHADSLNNLANIKREQGKIEESIRLYCKALEIFPEFAAAHSNLASVLQQQGKLQEALLHYKEAIRIHPTFADAFSNMGNLLKEMQDIQGAIQCYSRAIQI 420 HSP 3 Score: 68.1662 bits (165), Expect = 2.553e-11 Identity = 89/432 (20.60%), Postives = 161/432 (37.27%), Query Frame = 2
Query: 1583 EPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPY-----LAIRDFSIXXXXXXXXXNIMSYMY-RGILYATTKQFSEAI---VDF------------------EVVICFNKDMCFAHV------NLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSV--ALLNLLGTTQMKAKRWKD 2773
EPD +H C ++ + L +K++ AY + ++ G + A++N A++L PD + Y A G+ A+ Y ++ P+ G + + + A + + PS AW + G + + A+ F + LDPN AY G +L++A + +R ++S N+ Y +G++ + AI +F E C+N + + NL I E+G E+S++ L P + A+ A Q K ++A+ AI + P ++ + G+ M ++ A C +A +I+ + A VH + +AI + A + KPS A NL Q+ W D
Sbjct: 47 EPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVFKERGQLKDALANYRHAVKLKPDFIDGYINLAAALVAAGDLEGAVHAYATALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPSFAVAWSNLGCVFNAQGEIWLAIHHFEKAVQLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALNLSPNHAVVHGNLACVYYEQGLIDLAVDTYRRAIELQPNFPDAYCNLANALKEQGKVSEAEECYNTALQLSPTHADSLNNLANIKREQGKIEESIRLYCKALEIFPEFAAAHSNLASVLQQQGKLQEALLHYKEAIRIHPTFADAFSNMGNLLKEMQDIQGAIQCYSRAIQINPAFADAHSNLASVHKDSGNIPEAIQSYRTALKLKPSFPDAYCNLAHCLQIICD-WTD 477 HSP 4 Score: 57.3806 bits (137), Expect = 5.092e-8 Identity = 80/433 (18.48%), Postives = 171/433 (39.49%), Query Frame = 2
Query: 1874 QIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFK-RGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAY 3166
Q+ R +P+N ++ + + +A + ++ P EA+ + G + + Q +DAL ++ + L P+ Y L+ + A+ ++ +L + S + G L + EA + I A NLG ++ +G+ ++ + + DP ++ AY + ++ A+ RA++L P+ + + Y G +++A R+A E+ N + A +A + A + P+ A LN L + + + +++I + LE P A + +A + +++ L + ++I+P A+A+ + G + ++ I +RA+ INP A+ A++ +AI + L ++P AY
Sbjct: 42 QLWRREPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVFKERGQLKDALANYRHAVKLKPDFIDGYINLAAALVAAGDLEGAVHAYATALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPSFAVAWSNLGCVFNAQGEIWLAIHHFEKAVQLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALNLSPNHAVVHGNLACVYYEQGLIDLAVDTYRRAIELQPNFPDAYCNLANALKEQGKVSEAEECYNTALQLSPTHADSLNNLANIKREQGKIEESIRLYCKALEIF----------PEFAAAHSNLASVLQQQGKLQEALLHYKEAIRIHPTFADAFSNMGNLLKEMQDIQGAIQCYSRAIQINPAFADAHSNLASVHKDSGNIPEAIQSYRTALKLKPSFPDAY 462 HSP 5 Score: 51.9878 bits (123), Expect = 1.907e-6 Identity = 75/384 (19.53%), Postives = 159/384 (41.41%), Query Frame = 2
Query: 1514 GALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNI-----EQWQLAAKD--FSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLL-RKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM----NKYEDAIKDI----------NRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAA 2599
G L + +G L A AI +P +A+ + +I +AI ++ D N++ AY + + A++ +A+ LSP+ + + A +Y + G LA++ Y + I LQPN A Y N+ EQ +++ + +++ L+ P++ ++ + + + ++++ + + + P A+ +L ++ + A+ + ++ + + + S M G L + AI + I N AH NL ++ + G+ ++++ + L P++ AY C Q+ Y++ +K + NR + P S Y L +F A+ +CV + A
Sbjct: 160 GNLLKALGRLEEAKACYLKAIETQPSFAVAWSNLGCVFNAQGEIWLAIHHFEKAVQLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALNLSPNHAVVHGNLACVYYEQGLIDLAVDTYRRAIELQPNFPDA-------YCNLANALKEQGKVSEAEECYNTALQLSPTHADSLNNLANIKREQGKIEESIRLYCKALEIFPEFAAAHSNLASVLQQQGKLQEALLHYKEAIRIHPTFADAFSNM--GNLLKEMQDIQGAIQCYSRAIQINPAFADAHSNLASVHKDSGNIPEAIQSYRTALKLKPSFPDAY-CNLAHCLQIICDWTDYDNRMKKLVNIVAEQLEHNRLPSVHPHHSMLYPLTHEFRRAIANRH-GNLCVEKVA 532
BLAST of TPR_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO43484 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYL8]) HSP 1 Score: 65.0846 bits (157), Expect = 1.962e-10 Identity = 52/203 (25.62%), Postives = 91/203 (44.83%), Query Frame = 2
Query: 3701 NLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHV 4309
N+G R Q + ++A + A+ +P L+ + + +++ A K L A+ + ++N G V + A Y AI K P A+FN G +YI + +A+ FRK V+ W+N L+ +K E IE ++ P+ + ++FN N+L +R++EAE F L + P P +
Sbjct: 516 NIGKVRSTQQRDEEALAYYREAVRLNPTYSDALNNLGNLLKEKGEISEAEKLLERAVDSSKAFAAGWMNLGTVKAALNKMQEAETCYKNAIRYRK-KYPDAFFNLGNLYIDWNRDAEAVAAFRKAVKLKSDHVGAWMNHILLLDKTDKRTEGIELAYEALKHIPDESSIHFNLGNMLGQEKRFKEAEKHFLRALELNPVQPEI 717
BLAST of TPR_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO33965 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQP9]) HSP 1 Score: 63.5438 bits (153), Expect = 5.481e-10 Identity = 54/220 (24.55%), Postives = 96/220 (43.64%), Query Frame = 2
Query: 2918 FSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFN-AEKKNYEKAIQDYSIVLLI----SDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDH 3562
FS + +P + E + + +G++ + I D++ AL++ P + YL TL Y A N + L P A LY G+ Y AI + +A++ + N A +R++ E + A + ++ LL+ ++ HL RG++ G AL+DF Q+ P + LY+ VC+ L N E +++ T+ H
Sbjct: 68 FSTVISHSPKNPEGWIRRAEVLSPIGRIPEAIKDISVALSLQPSA-ELYLISGTLHFMSEDYVTATKNLEKSLEYNPSQATATLYLGLSLYHRGLIQQAIPLYKKALQANTNT--AEVHRSLGHAYRELGDASAAYEHFTAALLLEPRSAETFHL-------RGMLQYMNGKPALALNDFKACQSFDPQNTACLYMKAVCYATLGNFYETVKMSTKVRLH 277 HSP 2 Score: 62.7734 bits (151), Expect = 1.056e-9 Identity = 54/240 (22.50%), Postives = 96/240 (40.00%), Query Frame = 2
Query: 1856 ALEDYNQIIRLQPNNCLAMMKHGLYYLNI-----EQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMG 2560
A+ + +II+ P A + G Y+ E A DFS+V+ H P N E W+ R + + + +A+ D S + L P+ L Y G L +E Y+ ++ LE + + +Y G+ +AI ++ + N + H +LG Y E GD + ++ T+ L +P + R + K A+ D P + ++ Y +G
Sbjct: 25 AISYFTKIIKEHPKVTSAFLGRGTAYVKKGIQIKENSDAAISDFSTVISHSPKNPEGWIRRAEVLSPIGRIPEAIKDISVALSLQPSAEL-YLISGTLHFMSEDYVTATK-NLEKSLEYNPSQATATLYLGLSLYHRGLIQQAIPLYKKALQANTNTAEVHRSLGHAYRELGDASAAYEHFTAALLLEPRSAETFHLRGMLQYMNGKPALALNDFKACQSFDPQNTACLYMKAVCYATLG 262 HSP 3 Score: 62.003 bits (149), Expect = 1.760e-9 Identity = 65/268 (24.25%), Postives = 105/268 (39.18%), Query Frame = 2
Query: 1592 LIIAYWERHLLHLV-CNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTG-----DISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWL-------HRGT---------------------------AYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCL-LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAI 2272
L +++ H + L+ C I AI I+K+ A+ R Y G + AIS+ S I SP + E + +RAE+ G A++D + + LQP+ L ++ L++++ E + A K+ L + PS A L HRG AY +L A F+A + L+P + + RG L +P LA+ DF +N + + YAT F E +
Sbjct: 4 LFVSFITAHAISLLGCGDIDDAISYFTKIIKEHPKVTSAFLGRGTAYVKKGIQIKENSDAAISDFSTVISHSPKNPEGWIRRAEVLSPIGRIPEAIKDISVALSLQPSAELYLISGTLHFMS-EDYVTATKNLEKSLEYNPSQATATLYLGLSLYHRGLIQQAIPLYKKALQANTNTAEVHRSLGHAYRELGDASAAYEHFTAALLLEPRSAETFHLRGMLQYMNGKPALALNDFK--ACQSFDPQNTACLYMKAVCYATLGNFYETV 268
BLAST of TPR_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO43788 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXJ9]) HSP 1 Score: 58.5362 bits (140), Expect = 1.713e-8 Identity = 46/207 (22.22%), Postives = 87/207 (42.03%), Query Frame = 2
Query: 3833 DLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLY----------------------------------FNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDS 4351
+L+ L E R P++ + G + L ++ A+K + +A+ + C AY G Y+ +L++A+ C+R + SDP W + ++Y Q K + + +++S++P+S+ LY F+RA++LF + +YQEA + +I P + V G K G +
Sbjct: 540 ELSSLAHHLVEVDRSSPEA---WCATGNCFSLQKEHDTAIKFFQRAVQVDQ-ACTYAYTLLGHEYVLTEELDRAMSCYRMAIRSDPRHYNAWYGVGMIYYKQEKFNLAEVHFRKALSINPSSSVLYCHVGVVQHAMRKSEAALATINKAMLIDPKNPLCKFHRASILFSIDKYQEALHELEDLKKIVPREALVYFLIGKVYKKLGQA 742 HSP 2 Score: 51.9878 bits (123), Expect = 2.063e-6 Identity = 53/222 (23.87%), Postives = 89/222 (40.09%), Query Frame = 2
Query: 3392 GLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQAL 4057
G + EL + Q A F + Q + P+ L + + L+ E + ++ D A + GN F + D A K + +++D A LG + +A + MAI P G ++ + N A +A+ I P SS+LY + GVV MR A+ NKA++I K P+ F+ + + ++AL
Sbjct: 495 GRAHFELAEYQLAEKVFSQVQHLDPSRLEGMEIYSTILWHLQKEVELSSLAHHLVEVDRSSPEAWCATGNCF---SLQKEHDTAIKFFQRAVQVDQACTYAYTLLGHEYVLTEELDRAMSCYRMAIRSDPRHYNAWYGVGMIYYKQEKFNLAEVHFRKALSINPSSSVLYCHVGVVQHAMRKSEAALATINKAMLIDP-KNPLCKFHRASILFSIDKYQEAL 712
BLAST of TPR_REGION domain-containing protein vs. Ensembl Medaka
Match: ogt.1 (O-linked N-acetylglucosamine (GlcNAc) transferase [Source:NCBI gene;Acc:101164571]) HSP 1 Score: 96.2857 bits (238), Expect = 1.718e-19 Identity = 123/517 (23.79%), Postives = 212/517 (41.01%), Query Frame = 2
Query: 2840 PGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPR--CLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDL-QRYQEAELDFCSCL-RIAPDDPHVLKARG 4324
P + L++ + + + +S + +K NP AEAY + G G++++ I AL + P Y+ A A+ L P C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + + + A + YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I ++L++ NR S+ P+ + LY N + +R+ LD + L + A + P LKA G
Sbjct: 42 PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSE---AEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLDK-----NRLPSVHPHHSMLYPLSHNFRKAIAERHGNLCLDKINALHKPAYEHPKDLKASG 543 HSP 2 Score: 77.411 bits (189), Expect = 9.777e-14 Identity = 101/476 (21.22%), Postives = 197/476 (41.39%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRL----------RLGKMKQGI---LDLNRALAINPRLYQAYLARATLFGFKNQYTKAI 3115
AI+ +P +EAYS +Y++ G+ + A+E Y +RL+P+ Y+N+ +AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A + N A+ L P ++ + G +E A R+A E+ NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C R+ K+ + LD NR +++P + L+ + + KAI
Sbjct: 71 AIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG-------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLDKNRLPSVHPH-------HSMLYPLSHNFRKAI 513 HSP 3 Score: 75.8702 bits (185), Expect = 3.176e-13 Identity = 90/424 (21.23%), Postives = 160/424 (37.74%), Query Frame = 2
Query: 3119 NCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+C ++ EP L + ++ + + T AIK + A+ N + E+ ++AI+ Y L + YIN + GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP P AY N + +A EC+ + P NLA + Q +EE+++ +++ + P A + N A+VL + QEA + + +RI+P G+ + D GAL+ Y ++ I
Sbjct: 33 HCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYK-ERGQLQEAIEHYRHALRLKPDF---IDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPH-----------------------------------FPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI 414 HSP 4 Score: 58.9214 bits (141), Expect = 4.958e-8 Identity = 86/461 (18.66%), Postives = 178/461 (38.61%), Query Frame = 2
Query: 1796 DSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYR---GILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAY 3166
DS ++ A Q+G+ A Q+ R +P+N ++ + + +A + ++ P EA+ + G Y + Q Q+A+ + + L P+ Y L A + ++ + + + N Y R G L + EA + I + A NLG ++ +G+ ++ + + DP ++ AY + ++ A+ RA+ L P+ + + Y G +++A R+A E+ + + A + +A + A R P+ A LN L + + ++A+ + LE P A + +A + +++ + + ++I+P A+AY + G + ++ + RA+ INP A+ A++ +AI + L ++P AY
Sbjct: 10 DSTGLAELAHREYQSGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAA----GDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVF----------PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 456 HSP 5 Score: 55.8398 bits (133), Expect = 4.327e-7 Identity = 81/377 (21.49%), Postives = 141/377 (37.40%), Query Frame = 2
Query: 1484 RPN-AFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL--AAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM----NKYEDAIK----------DINRAIHLFPDRSNFYMLRGDFYLAMGK 2563
+PN A S G ++ G + A A++++P+ + AY + A+ L N+ + + + A +Y G I LAI +AI L P +AY A ++ G A E YN +RL P + ++ + L + EQ + A + + L +P A + + + + Q+AL + I + P AY G L++ ++D +G L T+ I N AH NL I+ + G+ +++ + L P + AY C Q+ Y++ +K D NR + P S Y L +F A+ +
Sbjct: 177 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSL--NNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKE------MQDV------------------QGALQCYTR-----------AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY-CNLAHCLQIVCDWTDYDERMKKLVSIVADQLDKNRLPSVHPHHSMLYPLSHNFRKAIAE 515
BLAST of TPR_REGION domain-containing protein vs. Ensembl Medaka
Match: ogt.1 (O-linked N-acetylglucosamine (GlcNAc) transferase [Source:NCBI gene;Acc:101164571]) HSP 1 Score: 83.1889 bits (204), Expect = 1.525e-15 Identity = 121/521 (23.22%), Postives = 206/521 (39.54%), Query Frame = 2
Query: 2840 PGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAY------YHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA------------------LVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDL-QRYQEAELDFCSCL-RIAPDDPHVLKARG 4324
P + L++ + + + +S + +K NP AEAY Y + + G M+ + AL NP LY C+R+ L G L + A + +AI+ N +A+ N FNA+ + + AI + + + AYIN G V E A+ ++RA ++ PN V + +++ + AI + R ++ P F A + N + + + A + YN+ L + H D+L NL ++ QG ++A ++ A+E P A V Q L AL EAIRI P + Y N G + M+D A++ Y +AI I A+ N ++ + + +A+ +R ++ P + NLA LV I ++L++ NR S+ P+ + LY N + +R+ LD + L + A + P LKA G
Sbjct: 42 PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERAALVAAGDMEGAVQAYVSALQYNPDLY--------------------------------CVRSDL--GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNF---LDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSE---AEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD-AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLDK-----NRLPSVHPHHSMLYPLSHNFRKAIAERHGNLCLDKINALHKPAYEHPKDLKASG 515 HSP 2 Score: 72.7886 bits (177), Expect = 2.359e-12 Identity = 79/345 (22.90%), Postives = 133/345 (38.55%), Query Frame = 2
Query: 3374 KAYINRGLVYLE------LGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+AY N G VY E GD++ A+ ++ A P+ V +G L L+EA + + ++ P F +A + G VF N+ LA + + +D LDA +NLG + F +A + A+ PN A V + ++ A+ AI +QP P AY N + +A EC+ + P NLA + Q +EE+++ +++ + P A + N A+VL + QEA + + +RI+P G+ + D GAL+ Y ++ I
Sbjct: 80 EAYSNLGNVYKERAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF---NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPH-----------------------------------FPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI 386 HSP 3 Score: 55.8398 bits (133), Expect = 4.047e-7 Identity = 81/377 (21.49%), Postives = 141/377 (37.40%), Query Frame = 2
Query: 1484 RPN-AFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL--AAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQM----NKYEDAIK----------DINRAIHLFPDRSNFYMLRGDFYLAMGK 2563
+PN A S G ++ G + A A++++P+ + AY + A+ L N+ + + + A +Y G I LAI +AI L P +AY A ++ G A E YN +RL P + ++ + L + EQ + A + + L +P A + + + + Q+AL + I + P AY G L++ ++D +G L T+ I N AH NL I+ + G+ +++ + L P + AY C Q+ Y++ +K D NR + P S Y L +F A+ +
Sbjct: 149 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSL--NNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKE------MQDV------------------QGALQCYTR-----------AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY-CNLAHCLQIVCDWTDYDERMKKLVSIVADQLDKNRLPSVHPHHSMLYPLSHNFRKAIAE 487 HSP 4 Score: 55.4546 bits (132), Expect = 4.713e-7 Identity = 100/490 (20.41%), Postives = 194/490 (39.59%), Query Frame = 2
Query: 1736 TGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQL-AAKDFSSVLRHYPS----NTEAWLHR---GTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRL----------RLGKMKQGI---LDLNRALAINPRLYQAYLARATLFGFKNQYTKAI 3115
+GD A + Q R PD++ + ++ Q RL + + ++ N LA L + E+ L AA D ++ Y S N + + R G L + ++A + I PN +A+ GC+ + E +LAI F ++ L+ + + +Y+ G + + F A+ + + + + H NL +Y+E+G + ++ + P + AY A A + +A + N A+ L P ++ + G +E A R+A E+ NL QQ + L HY +AI R P+ A + +G T + + + A+ +T ++ P A+ + +A + + N ++ ++ +K+ P+ +AY + C R+ K+ + LD NR +++P + L+ + + KAI
Sbjct: 24 SGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCR--RLDRSAHFSTLAIKQNPMLAEAYSNLGNVYKERAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLD--AYINLGNVLKEARIFDRAVAGYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGNVSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI-------RISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ----------INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLDKNRLPSVHPH-------HSMLYPLSHNFRKAI 485
BLAST of TPR_REGION domain-containing protein vs. Ensembl Medaka
Match: ttc13 (tetratricopeptide repeat domain 13 [Source:NCBI gene;Acc:101171797]) HSP 1 Score: 77.411 bits (189), Expect = 9.718e-14 Identity = 57/232 (24.57%), Postives = 111/232 (47.84%), Query Frame = 2
Query: 2888 LKNYKKSQLAF---SATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINP--RLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDP 3568
L++ K + LA + + + PN E Y + LG++ + + DL +A+ + P RLY+ R TL Y A+ + L ++ A LY+G+ + AI+ F EA+K+ ++ I A+ + + E ++E A++ + L+++ H ++ RG++ G +Q AL +F R ++P + Y+ G+ H + E I+ T+ + +DP
Sbjct: 158 LQDIKNADLALYELNRVIALEPNWPEVYEQRAEILSPLGRISEALSDLTKAIQLQPSARLYR---HRGTLLFISEDYVAAMEDFQRSLELKKNQPIAMLYKGLTYFHRGMLKEAIETFKEALKLKSDFIDAYKSLGQAYR-ELGDFESAMESFQKALMMNQN---HIQSLQLRGMMLYHHGSLQEALGNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 382 HSP 2 Score: 73.9442 bits (180), Expect = 1.108e-12 Identity = 62/248 (25.00%), Postives = 115/248 (46.37%), Query Frame = 2
Query: 1838 NGEGRLALEDYNQIIRLQPNNCLAMMKHGLYY-----LNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLA-IRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGK 2563
NG A++ ++ +++ P A+ G+ Y +I+ LA + + V+ P+ E + R + L + +AL+D + I L P+ L Y RG LL +E Y+A + DF LE + ++ +Y+G+ Y EAI F+ + D A+ +LG Y E GDFE +++ L + +I++ R + ++A+ + R + L P ++G ++AMG+
Sbjct: 122 NGLYDEAIKHFSLLLQNDPELVSAIYGRGIAYGKKSLQDIKNADLALYELNRVIALEPNWPEVYEQRAEILSPLGRISEALSDLTKAIQLQPSARL-YRHRGTLLFISEDYVAAMEDFQ--RSLELKKNQPIAMLYKGLTYFHRGMLKEAIETFKEALKLKSDFIDAYKSLGQAYRELGDFESAMESFQKALMMNQNHIQSLQLRGMMLYHHGSLQEALGNFKRCLQLEPYNEVCQYMKGLSHVAMGQ 366 HSP 3 Score: 72.4034 bits (176), Expect = 3.462e-12 Identity = 64/258 (24.81%), Postives = 119/258 (46.12%), Query Frame = 2
Query: 3527 EAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKT--VESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAP 4294
EAI+ F+ L +DP+ + A RG + Y + +D+ D + Y L+ ++ L PN + RA + + ++ AL DL +AI++QP S+ LY +RG + + D + AM+D+ +++ + + PIA G Y H L++A+E F++ ++SD +D + +L Y E ++E +++ ++ N R +L+ QEA +F CL++ P
Sbjct: 127 EAIKHFSLLLQNDPELVSAIYGRG---IAYGKKSLQDIKNAD------LALYELNRVIAL-----------------------EPNWPEVYEQRAEILSPLGRISEALSDLTKAIQLQP-SARLYRHRGTLLFISEDYVAAMEDFQRSLELKKNQ-PIAMLYKGLTYFHRGMLKEAIETFKEALKLKSDFID--AYKSLGQAYRELGDFESAMESFQKALMMNQNHIQSLQLRGMMLYHHGSLQEALGNFKRCLQLEP 348 HSP 4 Score: 63.929 bits (154), Expect = 1.295e-9 Identity = 68/262 (25.95%), Postives = 110/262 (41.98%), Query Frame = 2
Query: 1652 AIEDLNLILKKDKNYVLAYKSRAGIYA--STGDIS---LAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDF-----SIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADP 2407
AI+ +L+L+ D V A R Y S DI LA+ L++ I L P+ E Y +RAE+ G AL D + I+LQP+ L + L +++ E + A +DF L + A L++G Y ++A+ F + L + AY G + Y + DF S L ++ +I S RG++ EA+ +F+ + GL + G F + +K T + DP
Sbjct: 128 AIKHFSLLLQNDPELVSAIYGRGIAYGKKSLQDIKNADLALYELNRVIALEPNWPEVYEQRAEILSPLGRISEALSDLTKAIQLQPSARLYRHRGTLLFIS-EDYVAAMEDFQRSLELKKNQPIAMLYKGLTYFHRGMLKEAIETFKEALKLKSDFIDAYKSLG------QAYRELGDFESAMESFQKALMMNQNHIQSLQLRGMMLYHHGSLQEALGNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 382 HSP 5 Score: 53.9138 bits (128), Expect = 1.378e-6 Identity = 49/209 (23.44%), Postives = 99/209 (47.37%), Query Frame = 2
Query: 1379 IEPVLDEVDEEFRGALFETL---LEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYP 1996
+EP EV E+ R + L E + +++K ++ +P+A L RG L VAA +D ++ ++ + IA + L + ++ AIE LK +++ AYKS Y GD A+ + +A+ ++ + ++ R + +G + AL ++ + ++L+P N + GL ++ + Q+ K + V+ + P
Sbjct: 177 LEPNWPEVYEQ-RAEILSPLGRISEALSDLTKAIQ--LQPSARLYRHRGTLLFISEDYVAAMEDFQRSLELKKNQPIAMLYKGLTYFHRGMLKEAIETFKEALKLKSDFIDAYKSLGQAYRELGDFESAMESFQKALMMNQNHIQSLQLRGMMLYHHGSLQEALGNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 382
BLAST of TPR_REGION domain-containing protein vs. Ensembl Medaka
Match: ttc13 (tetratricopeptide repeat domain 13 [Source:NCBI gene;Acc:101171797]) HSP 1 Score: 77.0258 bits (188), Expect = 1.111e-13 Identity = 57/232 (24.57%), Postives = 111/232 (47.84%), Query Frame = 2
Query: 2888 LKNYKKSQLAF---SATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINP--RLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDP 3568
L++ K + LA + + + PN E Y + LG++ + + DL +A+ + P RLY+ R TL Y A+ + L ++ A LY+G+ + AI+ F EA+K+ ++ I A+ + + E ++E A++ + L+++ H ++ RG++ G +Q AL +F R ++P + Y+ G+ H + E I+ T+ + +DP
Sbjct: 158 LQDIKNADLALYELNRVIALEPNWPEVYEQRAEILSPLGRISEALSDLTKAIQLQPSARLYR---HRGTLLFISEDYVAAMEDFQRSLELKKNQPIAMLYKGLTYFHRGMLKEAIETFKEALKLKSDFIDAYKSLGQAYR-ELGDFESAMESFQKALMMNQN---HIQSLQLRGMMLYHHGSLQEALGNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 382 HSP 2 Score: 73.559 bits (179), Expect = 1.214e-12 Identity = 62/248 (25.00%), Postives = 115/248 (46.37%), Query Frame = 2
Query: 1838 NGEGRLALEDYNQIIRLQPNNCLAMMKHGLYY-----LNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLA-IRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGK 2563
NG A++ ++ +++ P A+ G+ Y +I+ LA + + V+ P+ E + R + L + +AL+D + I L P+ L Y RG LL +E Y+A + DF LE + ++ +Y+G+ Y EAI F+ + D A+ +LG Y E GDFE +++ L + +I++ R + ++A+ + R + L P ++G ++AMG+
Sbjct: 122 NGLYDEAIKHFSLLLQNDPELVSAIYGRGIAYGKKSLQDIKNADLALYELNRVIALEPNWPEVYEQRAEILSPLGRISEALSDLTKAIQLQPSARL-YRHRGTLLFISEDYVAAMEDFQ--RSLELKKNQPIAMLYKGLTYFHRGMLKEAIETFKEALKLKSDFIDAYKSLGQAYRELGDFESAMESFQKALMMNQNHIQSLQLRGMMLYHHGSLQEALGNFKRCLQLEPYNEVCQYMKGLSHVAMGQ 366 HSP 3 Score: 72.4034 bits (176), Expect = 3.426e-12 Identity = 64/258 (24.81%), Postives = 119/258 (46.12%), Query Frame = 2
Query: 3527 EAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKT--VESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAP 4294
EAI+ F+ L +DP+ + A RG + Y + +D+ D + Y L+ ++ L PN + RA + + ++ AL DL +AI++QP S+ LY +RG + + D + AM+D+ +++ + + PIA G Y H L++A+E F++ ++SD +D + +L Y E ++E +++ ++ N R +L+ QEA +F CL++ P
Sbjct: 127 EAIKHFSLLLQNDPELVSAIYGRG---IAYGKKSLQDIKNAD------LALYELNRVIAL-----------------------EPNWPEVYEQRAEILSPLGRISEALSDLTKAIQLQP-SARLYRHRGTLLFISEDYVAAMEDFQRSLELKKNQ-PIAMLYKGLTYFHRGMLKEAIETFKEALKLKSDFID--AYKSLGQAYRELGDFESAMESFQKALMMNQNHIQSLQLRGMMLYHHGSLQEALGNFKRCLQLEP 348 HSP 4 Score: 63.5438 bits (153), Expect = 1.431e-9 Identity = 66/257 (25.68%), Postives = 110/257 (42.80%), Query Frame = 2
Query: 1652 AIEDLNLILKKDKNYVLAYKSRAGIYA--STGDIS---LAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADP 2407
AI+ +L+L+ D V A R Y S DI LA+ L++ I L P+ E Y +RAE+ G AL D + I+LQP+ L + L +++ E + A +DF L + A L++G Y ++A+ F + L + AY G R+ + + + S L ++ +I S RG++ EA+ +F+ + GL + G F + +K T + DP
Sbjct: 128 AIKHFSLLLQNDPELVSAIYGRGIAYGKKSLQDIKNADLALYELNRVIALEPNWPEVYEQRAEILSPLGRISEALSDLTKAIQLQPSARLYRHRGTLLFIS-EDYVAAMEDFQRSLELKKNQPIAMLYKGLTYFHRGMLKEAIETFKEALKLKSDFIDAYKSLGQAYRELGDFESAME-SFQKALMMNQNHIQSLQLRGMMLYHHGSLQEALGNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 382 HSP 5 Score: 53.9138 bits (128), Expect = 1.330e-6 Identity = 49/209 (23.44%), Postives = 99/209 (47.37%), Query Frame = 2
Query: 1379 IEPVLDEVDEEFRGALFETL---LEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYP 1996
+EP EV E+ R + L E + +++K ++ +P+A L RG L VAA +D ++ ++ + IA + L + ++ AIE LK +++ AYKS Y GD A+ + +A+ ++ + ++ R + +G + AL ++ + ++L+P N + GL ++ + Q+ K + V+ + P
Sbjct: 177 LEPNWPEVYEQ-RAEILSPLGRISEALSDLTKAIQ--LQPSARLYRHRGTLLFISEDYVAAMEDFQRSLELKKNQPIAMLYKGLTYFHRGMLKEAIETFKEALKLKSDFIDAYKSLGQAYRELGDFESAMESFQKALMMNQNHIQSLQLRGMMLYHHGSLQEALGNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 382
BLAST of TPR_REGION domain-containing protein vs. Ensembl Medaka
Match: DNAJC7 (dnaJ homolog subfamily C member 7 [Source:NCBI gene;Acc:101160690]) HSP 1 Score: 74.3294 bits (181), Expect = 4.447e-13 Identity = 77/352 (21.88%), Postives = 143/352 (40.62%), Query Frame = 2
Query: 2333 GLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLA---RATLFGFKNQYTKAILNCN---------EVLSIEPRCLRA----YLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIV 3340
G Y+ K D+ + Y T + A P Y RA + ++ +A++D +A+ L ++ G +L++G AA C ++ E+ + ++ ++ + L+ Y++ D K +C+++ P L A C L Y ++Q S ++++ +A+A Y +G C + + + +AL + P +A LA L K + + NC+ E L+I+P ++ Y R K+K + AI D T+AIK+D I A+ RA C+ + + YE+A++DY V
Sbjct: 49 GNAYYSKKDYPAAFNYYTKAIDASPKTASYYGNRAATLMMLCRFREALEDSQQAVRLDDGFMKGHLREGKCHLSLGNAMAAARCFQKVLELEPSNKEAQQEKKNATTLLE-YERMADFSFD------------------------KRDFRKVVYCMDRAIA------LAPTCQRFKILKAECLALLGRYPEAQSVASDILRMDATNADALYVRGLCLYYEDCIDKAVQFFVQALRMAPDHEKARLACRNAKALKAKKEEGNQVFKNCSYDAAYQLYTEALAIDPNNIKTNAKLYCNRATAGAKLKKFDQAIDDCTKAIKLDDTYIKAYLRRAQCY-MDTELYEEAVRDYEKV 368 HSP 2 Score: 53.9138 bits (128), Expect = 1.193e-6 Identity = 80/332 (24.10%), Postives = 123/332 (37.05%), Query Frame = 2
Query: 1643 IQMAIEDLNLILKKDK--NYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTA-----YAKLQQWQDALTDFSAVIH-------LDPN-NYLAYFKRGCLL---RKAEPYLAIRDFSIXXXXXXXXXNI--MSYMYRGILYATTKQFSEAI---VDFEV--VICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRA----YPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYL 2551
I M +E + I +D +K + Y S D A + ++AI SP + Y RA R ALED Q +RL ++ G +L++ AA+ F VL PSN EA + A Y ++ + DF V++ L P K CL R E D + + + Y + + F +A+ D E + C N A G F+ ++ + + T LA DP I+ Y RA A ++ K++ AI D +AI L Y+ R Y+
Sbjct: 22 IDMPVEPESQIRSQDDLDRQAEIFKEQGNAYYSKKDYPAAFNYYTKAIDASPKTASYYGNRAATLMMLCRFREALEDSQQAVRLDDGFMKGHLREGKCHLSLGNAMAAARCFQKVLELEPSNKEAQQEKKNATTLLEYERMADFSFDKRDFRKVVYCMDRAIALAPTCQRFKILKAECLALLGRYPEAQSVASDILRMDATNADALYVRGLCLYYEDCIDKAVQFFVQALRMAPDHEKARLACRNAKALKAKKEEGNQVFKNCSYDAAYQLYTEALAIDPNNIKTNAKLYCNRATAGAKLKKFDQAIDDCTKAIKLDDTYIKAYLRRAQCYM 353
BLAST of TPR_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000071973.1 (SMESG000071973.1) HSP 1 Score: 2878.97 bits (7462), Expect = 0.000e+0 Identity = 1422/1423 (99.93%), Postives = 1423/1423 (100.00%), Query Frame = 2
Query: 122 KDVSASSVERIEKAAERIISQKNEIEKWRTKANEMLNLTSEIEIVGTFISPSEPKIIDIWQPLAPRLFMSQNQVTNVLCPKYNPNIFEPTIEEVSKQNTFENFTSEDLTLSNEASFCNEIDLEALETKERLLSRKINSVECLADERIDENKFSKIIHQRKRCTSVPNRHWLEEDSLIVHLEYHQIMDEINIQRQKIRALKNTSEINEDINEKKPLEEDEKIFNDNFDSGILTTNVENEYKTHQSVKSIEDDCSSPAKNALRAGQNYIYYXXXXXXXXXXXXXXNIARISDIERFLGQPPNKLDKTKSFENIRIELKRIRSCXXXXXXXXXXXXXXXXADIHNFEDWSKNRGYKKESNARDWITVIWDQWFDEIYPPIPDHIIDLTSDKPSETPYKNELLNREPTSVSAIQNEILDLPENIEPVLDEVDEEFRGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
KDVSASSVERIEKAAERIISQKNEIEKWRTKANEMLNLTSEIEIVGTFISPSEPKIIDIWQPLAPRLFMSQNQVTNVLCPKYNPNIFEPTIEEVSKQNTFENFTSEDLTLSNEASFCNEIDLEALETKERLLSRKINSVECLADERIDENKFSKIIHQRKRCTSVPNRHWLEEDSLIVHLEYHQIMDEINIQRQKIRALKNTSEINEDINEKKPLEEDEKIFNDNFDSGILTTNVENEYKTHQSVKSIEDDCSSPAKNALRAGQNYIYYPPKKRSKSKPKKSKNIARISDIERFLGQPPNKLDKTKSFENIRIELKRIRSCKSREKSDLKKSLSKSLADIHNFEDWSKNRGYKKESNARDWITVIWDQWFDEIYPPIPDHIIDLTSDKPSETPYKNELLNREPTSVSAIQNEILDLPENIEPVLDEVDEEFRGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSISLLLESSEENIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGW+NLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI
Sbjct: 452 KDVSASSVERIEKAAERIISQKNEIEKWRTKANEMLNLTSEIEIVGTFISPSEPKIIDIWQPLAPRLFMSQNQVTNVLCPKYNPNIFEPTIEEVSKQNTFENFTSEDLTLSNEASFCNEIDLEALETKERLLSRKINSVECLADERIDENKFSKIIHQRKRCTSVPNRHWLEEDSLIVHLEYHQIMDEINIQRQKIRALKNTSEINEDINEKKPLEEDEKIFNDNFDSGILTTNVENEYKTHQSVKSIEDDCSSPAKNALRAGQNYIYYPPKKRSKSKPKKSKNIARISDIERFLGQPPNKLDKTKSFENIRIELKRIRSCKSREKSDLKKSLSKSLADIHNFEDWSKNRGYKKESNARDWITVIWDQWFDEIYPPIPDHIIDLTSDKPSETPYKNELLNREPTSVSAIQNEILDLPENIEPVLDEVDEEFRGALFETLLEEVKNISKDMENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSISLLLESSEENIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWINLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 1874
BLAST of TPR_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000002813.1 (SMESG000002813.1) HSP 1 Score: 97.4413 bits (241), Expect = 5.534e-20 Identity = 109/478 (22.80%), Postives = 187/478 (39.12%), Query Frame = 2
Query: 2885 ELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYL-------YRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPD 4297
+L NY+K++ K++PN++ +L K+ + A+ NP++ +AY +F K Q +AI + L ++P + AY+ G L I Y L + E + + + F K Y KAI+ Y + A+ N G ++ GD+ A+H F +A + PN L +G + K A+ +T+ L D + GN+ Y DLA Y +E+ DA NL + +G +A + A+ +PN L+ A + + A+ +A+ I P+ ++ + N + QL A+ Y +AI I AY N G + L A++C+++ ++ P NLA VY + E+I ++ + PN Y EA + CL+I D
Sbjct: 23 QLGNYEKAEKYCLEIWKLDPNNSAILLFLSSVYFQLKKLDKSAFFCQLAIKQNPQMAEAYSNLGNVFKEKGQLIEAISFYKQALQLKPNFIDAYINLASAFVAAGNLDNAISTYILVLNHNPELYHVRSE-LGNLFKALGKLEEAKSCYLKAIETYPAFAV----------AWSNVGCIFNAQGDIWLAIHHFEKAVTLDPNFLDAHVNLGHVFKEAKIFDRAVAAYTKALTLDSD---NPILHGNLACVYYEQGLYDLAIDSYRKAIELQPNFPDAYCNLANALKEKGNVLEAEKCYNTALRLNPNHADSLNNLANIKREQGLNEEAMNLYKKALEIYPEFAVAHSNLASMLQLQGHLQSALNHYREAIKISP-NFADAYSNMGNTFKELQDLPNAVQCYQRAIQIKPTFADAHSNLASVYKDTGNINEAIGSYTTALKIKPN-----------------YPEAFCNLTHCLQIVCD 468 HSP 2 Score: 79.337 bits (194), Expect = 2.127e-14 Identity = 102/434 (23.50%), Postives = 175/434 (40.32%), Query Frame = 2
Query: 3101 YTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCM----QMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
Y KA C E+ ++P L+ + +++K + AIK + A+ N F EK +AI Y L + AYIN ++ G++ NA+ +I P +V +G L L+EA + + ++ P F +A + G +F N+ LA + + +D LDA VNLG + F +A +T A+ +S+ P+ + C+ + DL A+ +AI +QP Y N + + + A K YN A+ + + N + E+A+ ++K +E P NLA + Q L+ ++ + +I +SPN A Y N N +LQ A + ++I P TG+ A+ Y T++ I
Sbjct: 27 YEKAEKYCLEIWKLDPNNSAILLFLSSVYFQLKKLDKSAFFCQLAIKQNPQMAEAYSNLGNVFK-EKGQLIEAISFYKQALQLKPNF---IDAYINLASAFVAAGNLDNAISTYILVLNHNPELYHVRSELGNLFKALGKLEEAKSCYLKAIETYPAFAVAWSNVGCIF---NAQGDIWLAIHHFEKAVTLDPNFLDAHVNLGHVFKEAKIFDRAVAAYTKALTL--DSDNPILHGNLACVYYEQGLYDL--AIDSYRKAIELQPNFPDAYCNLANALKEKGNVLEAEKCYNTALRLNPNHAD-SLNNLANIKREQGLNEEAMNLYKKALEIYPEFAVAHSNLASMLQLQGHLQSALNHYREAIKISPNFADAYSNMGNTFKELQDLPNAVQCYQRAIQIKPTFADAHSNLASVYKDTGNINEAIGSYTTALKI 448 HSP 3 Score: 71.2478 bits (173), Expect = 6.072e-12 Identity = 81/356 (22.75%), Postives = 147/356 (41.29%), Query Frame = 2
Query: 3344 LISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEA-------IRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+IS AL ++ Y +LG+ + A + + PN+ +L + + +LK L ++ + +P+ A + GNVF + A Y L++ +DA +NL A G A + + + +P V ++ +L AL L EA I P ++ + N G ++ D +A+ + KA+ + A+ N G V+ ++A+ + K + D + NLA VY Q + +I+ ++I L PN Y N AN L + EAE + + LR+ P+ L + + + G + A+ YK ++ I
Sbjct: 10 MISQALSFAHREY--------QLGNYEKAEKYCLEIWKLDPNNSAILLFLSSVYFQLKKLDKSAFFCQLAIKQNPQMAEAYSNLGNVFKE---KGQLIEAISFYKQALQLKPNFIDAYINLASAFVAAGNLDNAISTYILVLNHNPELYH-------VRSELGNLFKALGKLEEAKSCYLKAIETYPAFAVAWSNVGCIFNAQGDIWLAIHHFEKAVTLDP-NFLDAHVNLGHVFKEAKIFDRAVAAYTKALTLDSDNPILHGNLACVYYEQGLYDLAIDSYRKAIELQPNFPDAYCNLANALKEKGNVLEAEKCYNTALRLNPNHADSLNNLANIKREQGLNEEAMNLYKKALEI 346 HSP 4 Score: 68.1662 bits (165), Expect = 4.923e-11 Identity = 91/445 (20.45%), Postives = 169/445 (37.98%), Query Frame = 2
Query: 1670 LILKKDKNYVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI-------SHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSVA-LLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWC 2980
L +K++ AY + ++ G + AIS QA++L P+ +AY A + G A+ Y ++ P + G + + + + A + + YP+ AW + G + A+ F + LDPN A+ G + ++A K F A+ + + + D H NL +Y+E+G ++ ++ + P + AY A A + +A K N A+ L P+ ++ + G E A ++A EI NL Q + S L HY +AI + P+ A + +G T + + +A+ + + Q+KP + +NL A Y + N ++ +++ +KI PN+ EA+ + C
Sbjct: 70 LAIKQNPQMAEAYSNLGNVFKEKGQLIEAISFYKQALQLKPNFIDAYINLASAFVAAGNLDNAISTYILVLNHNPELYHVRSELGNLFKALGKLEEAKSCYLKAIETYPAFAVAWSNVGCIFNAQGDIWLAIHHFEKAVTLDPNFLDAHVNLGHVFKEA-----------------------------------KIFDRAVAAYTKALTLDSDNPILHGNLACVYYEQGLYDLAIDSYRKAIELQPNFPDAYCNLANALKEKGNVLEAEKCYNTALRLNPNHADSLNNLANIKREQGLNEEAMNLYKKALEIYPEFAVAHSNLASMLQLQGHLQSALNHYREAI-------KISPNFADAYSNMGNTFKELQDLPNAVQCYQRAI-QIKPT-----FADAHSNL----ASVYKDTGNINEAIGSYTTALKIKPNYPEAFCNLTHC 462 HSP 5 Score: 63.5438 bits (153), Expect = 1.200e-9 Identity = 102/460 (22.17%), Postives = 182/460 (39.57%), Query Frame = 2
Query: 2222 MYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEIS-------HNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSV--ALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKF 3574
++ +Y K+ ++ ++ I N M A+ NLG ++ EKG +++ + L P +I AY A A+ ++AI ++ P+ + G+ + A+GK+E A C +A E N+G Q + + H+++A+ P+ A +N LG +AK + A+ ++T L L N P NL A Y E Y + ++ +++ PN +AY + G + + N AL +NP + A + + +A+ + L I P A+ + A+ + EAIKI N A+ N F E ++ A+Q Y + I A+ N VY + G++ A+ + A I+PN Y C NL +++ D+D +
Sbjct: 49 LFLSSVYFQLKKLDKSAFFCQLAIKQNPQMAEAYSNLGNVFKEKGQLIEAISFYKQALQLKPNFIDAYINLASAFVAAGNLDNAISTYILVLNHNPELYHVRSELGNLFKALGKLEEAKSCYLKAIETYPAFAVAWSNVGCIFNAQGDIWLAIHHFEKAVTL-------DPNFLDAHVN-LGHVFKEAKIFDRAVAAYTKAL-TLDSDN-----PILHGNL----ACVYYEQGLYDLAIDSYRKAIELQPNFPDAYCNLANALKEKGNVLEAEKCYNTALRLNPNHADSLNNLANIKREQGLNEEAMNLYKKALEIYPEFAVAHSNLASMLQLQGHLQSALNHYREAIKISPNFADAYSNMGNTFK-ELQDLPNAVQCYQRAIQIKPTF---ADAHSNLASVYKDTGNINEAIGSYTTALKIKPN-----YPEAFC-----NLTHCLQIVCDWADYDTRM 476 HSP 6 Score: 53.5286 bits (127), Expect = 1.386e-6 Identity = 99/473 (20.93%), Postives = 188/473 (39.75%), Query Frame = 2
Query: 2345 FEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKPSV-ALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLV---ARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAI---NPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYL-YRGVLKYKIKAYSLAIKDFTEAIKIDANCI-----LAFFNRAVCFNAEKKN-YEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQ 3721
++ G++EK+ KY DP + YFQ+ K + + AI P + Y G+ + G++ A +QA ++ N + + A + D AI ++ P + + + LG + ++A + + LK Y + +N+ + +L + +++K+ V ++PN +A+ + G + + +AL + NP L+ A ++ + Y AI + + + ++P AY LK K A K + A++++ N LA R N E N Y+KA++ Y + A+ N + G +Q+AL+ + A I PN +G +L++L A++ + R + P F A + +V+ D + N A Y + L+I + +A NL C Q
Sbjct: 22 YQLGNYEKAEKYCLEIWKLDPNNSAILLFLSSVYFQLKKLDKSAFFCQLAIKQNPQMAEAYSNLGNVFKEKGQLIEAISFYKQALQLKPNFIDAYINLASAFVAAGNLDNAISTYILVLNHNPELYHVRSELGNLFKALGKLEEAKSCY------LKAIETYPAFAVAWSNVGCIFNAQGDIWLAIHHFEKA-------VTLDPNFLDAHVNLGHVFKEAKIFDRAVAAYTKALTLDSDNPILHGNL---ACVYYEQGLYDLAIDSYRKAIELQPNFPDAYCNLANALKEKGNVLE-AEKCYNTALRLNPNHADSLNNLANIKREQGLNEEAMNLYKKALEIYPEFAV----------AHSNLASMLQLQGHLQSALNHYREAIKISPNFADAYSNMGNTFKELQDLPNAVQCYQRAIQIKPTFADAHSNLASVYKDTGNINE---AIGSYTTALKIKPNYPEAFCNLTHCLQ 464
BLAST of TPR_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000004465.1 (SMESG000004465.1) HSP 1 Score: 95.5153 bits (236), Expect = 7.116e-20 Identity = 107/434 (24.65%), Postives = 177/434 (40.78%), Query Frame = 2
Query: 2840 PGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKK------NYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKE-AIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLA 4120
P + L++ Y +++ KS +K NP AEAY + G G++ + I + AL I P YL A F AI VL+ P G L + A + +AI+ +A+ N FNA+ + ++EKA+ L AY+N G V+ E A+ +++A + PN+ +++ C + +NL E AI + R ++ P F A + N + + A + YN+ L + H D+L NL ++ Q ++A ++ A+E +P A + LN AL EAIRI P + Y N G + M+D AM+ Y +AI I A+ N +Y + A+ ++ ++ P + NLA
Sbjct: 44 PHNTAILLLLSSIYFQMRKLDKSGFFCQLAIKQNPQMAEAYSNLGNVLKEKGQLAEAIENYKHALRIKPEFIDGYLNLAAAFVAAGHMESAISTYMIVLNNNPDLYYVRSDLGNLFKALGRLDEAKSCYLKAIETCPQFAVAWSNLGCVFNAQSEIWLAIHHFEKAVSLDPNFL----------DAYLNLGNVFKEARIFDRAVTAYLKALNLAPNNA-IIHGNLACVYYEQNLVELAIDTYKRAIELQPNFPDAYCNLANALKEKGKVSE---AEECYNTALRLQPTHADSLNNLANIKREQCHSEEAMQLYVRALEIYPEFAVAHSNLASMLQLQGKLNEALMHYREAIRISPNFADAYSNMGNTLKEMQDINGAMQCYQRAIQINPTFAD-AHSNLASIYKDTGNINDAISSYKTALKIKPNYHDAFCNLA 462 HSP 2 Score: 78.9518 bits (193), Expect = 1.350e-14 Identity = 97/431 (22.51%), Postives = 173/431 (40.14%), Query Frame = 2
Query: 3098 QYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEAIRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
Y +A +C ++ IEP L + ++++ + AIK + A+ N EK +AI++Y L I Y+N ++ G +++A+ ++ P+ YV +G L L EA + + ++ P+F +A + G VF N+ + LA + + +D LDA +NLG + F +A + A+ PN+ A V + + + A+ AI +QP Y N + A + YN A+ + + N + E+A++ + + +E P NLA + Q KL E++ + +I +SPN A Y N N L ++Q A + ++I P TG+ A+ YKT++ I
Sbjct: 28 HYERAEKHCIDLWKIEPHNTAILLLLSSIYFQMRKLDKSGFFCQLAIKQNPQMAEAYSNLGNVLK-EKGQLAEAIENYKHALRIKPEF---IDGYLNLAAAFVAAGHMESAISTYMIVLNNNPDLYYVRSDLGNLFKALGRLDEAKSCYLKAIETCPQFAVAWSNLGCVF---NAQSEIWLAIHHFEKAVSLDPNFLDAYLNLGNVFKEARIFDRAVTAYLKALNLAPNNAIIHGNLACVYYEQNLVELAIDTYKRAIELQPNFPDAYCNLANALKEKGKVSEAEECYNTALRLQPTHAD-SLNNLANIKREQCHSEEAMQLYVRALEIYPEFAVAHSNLASMLQLQGKLNEALMHYREAIRISPNFADAYSNMGNTLKEMQDINGAMQCYQRAIQINPTFADAHSNLASIYKDTGNINDAISSYKTALKI 450 HSP 3 Score: 74.3294 bits (181), Expect = 3.769e-13 Identity = 83/366 (22.68%), Postives = 153/366 (41.80%), Query Frame = 2
Query: 3314 KAIQDYSIVLLISDALHLHYKAYINRGLVYLELGDVQNALHDFIRAQAIQPNDLYVLYVVGVCHHKLKNLKEAIRVFTRCLDHDPKFILAKVSRGNVFMDYNSSNSRDLAAKDYNSVLEIDSYHLDALVNLGFCRQAQGKFKKAWDIFTMAIEKHPNSERPLDGRAIVCMQMSDLNGALKDLNEA-------IRIQPQSSMLYINRGVVYQLMRDKIMAMKDYNKAIIIGGLKCPIAYFNAGCVYIHNFQLEQALECFRKTVESDPLDEAGWVNLALVYIFQNKLEESIEYINRSISLSPNSAYLYFNRANVLFDLQRYQEAELDFCSCLRIAPDDPHVLKARGDCRSKTGDSLGALEDYKTSVYI 4390
+AIQ+ + + + H Y+A G + A I I+P++ +L ++ + +++ L ++ + +P+ A + GNV + A ++Y L I +D +NL A G + A + + + +P+ V + +L AL L+EA I PQ ++ + N G V+ + +A+ + KA+ + AY N G V+ ++A+ + K + P + NLA VY QN +E +I+ R+I L PN Y N AN L + + EAE + + LR+ P L + + + S A++ Y ++ I
Sbjct: 5 QAIQNGMTTMQVLELAHREYQA-----------GHYERAEKHCIDLWKIEPHNTAILLLLSSIYFQMRKLDKSGFFCQLAIKQNPQMAEAYSNLGNVLKEKGQLAE---AIENYKHALRIKPEFIDGYLNLAAAFVAAGHMESAISTYMIVLNNNPD-------LYYVRSDLGNLFKALGRLDEAKSCYLKAIETCPQFAVAWSNLGCVFNAQSEIWLAIHHFEKAVSLDP-NFLDAYLNLGNVFKEARIFDRAVTAYLKALNLAPNNAIIHGNLACVYYEQNLVELAIDTYKRAIELQPNFPDAYCNLANALKEKGKVSEAEECYNTALRLQPTHADSLNNLANIKREQCHSEEAMQLYVRALEI 348 HSP 4 Score: 59.6918 bits (143), Expect = 1.312e-8 Identity = 89/399 (22.31%), Postives = 161/399 (40.35%), Query Frame = 2
Query: 2282 EVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLR---GDFYLAMGKMEMAAICVRQAAEIS-------HNLG-----QSPVQQALVH---------SFLQHY-------------DQAIDALLVATRGKPSVALLNL-LGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAYLARATLFGFKNQYTKAILNCNEVLSIEPRCLRAYLYRGVLKYKIKAYSLAIKDFTEAIKIDANCILAFFNRAVCFNAEKKNYEKAIQDYSIVLLISDALH 3364
++ I N M A+ NLG + EKG ++++ L P +I Y A A+ E AI ++ PD Y +R G+ + A+G+++ A C +A E NLG QS + A+ H +FL Y D+A+ A L A P+ A+++ L + + AI ++ +E L+P +P NL A E +++ ++ +++ P HA++ + + ++ + RAL I P A+ A++ + + +A+++ E + I P AY G +++ + A++ + AI+I+ A N A + + N AI Y L I H
Sbjct: 71 QLAIKQNPQMAEAYSNLGNVLKEKGQLAEAIENYKHALRIKPEFIDGYLNLAAAFVAAGHMESAISTYMIVLNNNPD---LYYVRSDLGNLFKALGRLDEAKSCYLKAIETCPQFAVAWSNLGCVFNAQSEIWLAIHHFEKAVSLDPNFLDAYLNLGNVFKEARIFDRAVTAYLKALNLAPNNAIIHGNLACVYYEQNLVELAIDTYKRAIE-LQPN-----FPDAYCNL----ANALKEKGKVSEAEECYNTALRLQPTHADSLNNLANIKREQCHSEEAMQLYVRALEIYPEFAVAHSNLASMLQLQGKLNEALMHYREAIRISPNFADAYSNMGNTLKEMQDINGAMQCYQRAIQINPTFADAHSNLASIYK-DTGNINDAISSYKTALKIKPNYH 455 HSP 5 Score: 58.151 bits (139), Expect = 3.906e-8 Identity = 85/433 (19.63%), Postives = 159/433 (36.72%), Query Frame = 2
Query: 1775 AIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCLLR-KAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEISHNLGQSPVQQALVHSFLQHYDQAIDALLVATRGKP--SVALLNLLGTTQMKAKRWKDAITSFTFCLEQLKPKNQYKPWPPGAANLNFLVARCYLELKNYKKSQLAFSATVKINPNHAEAYYHQGWCRLRLGKMKQGILDLNRALAINPRLYQAY 3064
AI+ +P +EAYS + ++ G+ A+E+Y +R++P + ++ + A + VL + P G + L + +A + + I P +A+ GC+ ++E +LAI F E + + + A++NLG ++ E F+++V L P + A Y++ N E AI RAI L P+ + Y + GK+ A C A + S A + H ++A+ + A P +VA NL Q++ K +A+ + + P A+ + E+++ + + ++INP A+A+ + G + I AL I P + A+
Sbjct: 73 AIKQNPQMAEAYSNLGNVLKEKGQLAEAIENYKHALRIKPEFIDGYLNLAAAFVAAGHMESAISTYMIVLNNNPDLYYVRSDLGNLFKALGRLDEAKSCYLKAIETCPQFAVAWSNLGCVFNAQSEIWLAIHHF------------------------------------EKAVSLDPNFLDAYLNLGNVFKEARIFDRAVTAYLKALNLAPNNAIIHGNLACVYYEQNLVELAIDTYKRAIELQPNFPDAYCNLANALKEKGKVSEAEECYNTALRLQPTHADSLNNLANIKREQCHSEEAMQLYVRALEIYPEFAVAHSNLASMLQLQGK-LNEALMHYREAIR----------ISPNFADAYSNMGNTLKEMQDINGAMQCYQRAIQINPTFADAHSNLASIYKDTGNINDAISSYKTALKIKPNYHDAF 458 HSP 6 Score: 53.1434 bits (126), Expect = 1.549e-6 Identity = 69/386 (17.88%), Postives = 144/386 (37.31%), Query Frame = 2
Query: 1472 ENYQRPNAFLLSRRGALYRKMGYLVAASKDINDAISIEPDLIIAYWERHLLHLVCNKIQMAIEDLNLILKKDKN----------------------------------YVLAYKSRAGIYASTGDISLAISNLSQAIRLSPDDSEAYSKRAELYEQNGEGRLALEDYNQIIRLQPNNCLAMMKHGLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPN-----NYLAYFKRGCLLRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAHVNLGLIYFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPD 2512
+N Q A+ S G + ++ G L A ++ A+ I+P+ I Y + ++ AI ++L + + + +A+ + ++ + +I LAI + +A+ L P+ +AY ++++ A+ Y + + L PNN + Y +LA + + P+ +A+ + A + + +A ++ + L P N LA KR + L +R I + N+ S + + +EA++ + I + + A+ N+G E D +++ + +PT+ A+ A Y DAI A+ + P+
Sbjct: 76 QNPQMAEAY--SNLGNVLKEKGQLAEAIENYKHALRIKPEFIDGYLNLAAAFVAAGHMESAISTYMIVLNNNPDLYYVRSDLGNLFKALGRLDEAKSCYLKAIETCPQFAVAWSNLGCVFNAQSEIWLAIHHFEKAVSLDPNFLDAYLNLGNVFKEARIFDRAVTAYLKALNLAPNNAIIHGNLACVYYEQNLVELAIDTYKRAIELQPNFPDAYCNLANALKEKGKVSEAEECYNTALRLQPTHADSLNNLANIKREQCHSEEAMQLYVRALEIYPEFAVAHSNLASML------QLQGKLNEALMHYREAIRISPNFADAYSNMGNTLKEMQDINGAMQCYQRAIQINPTFADAHSNLASIYKDTGNINDAISSYKTALKIKPN 453
BLAST of TPR_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000040140.1 (SMESG000040140.1) HSP 1 Score: 58.151 bits (139), Expect = 5.225e-8 Identity = 25/64 (39.06%), Postives = 37/64 (57.81%), Query Frame = 2
Query: 1922 GLYYLNIEQWQLAAKDFSSVLRHYPSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLA 2113
GL Y+ + W+ A +D S L+ PSN +A R + Y+++ QDA+TD +I L PNN A
Sbjct: 259 GLVYMKQKNWEEAIRDLSITLKKDPSNIKALQRRASCYSEIHNLQDAITDCRKIIKLSPNNKFA 322
BLAST of TPR_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000009124.1 (SMESG000009124.1) HSP 1 Score: 55.4546 bits (132), Expect = 2.844e-7 Identity = 54/217 (24.88%), Postives = 90/217 (41.47%), Query Frame = 2
Query: 1994 PSNTEAWLHRGTAYAKLQQWQDALTDFSAVIHLDPNNYLAYFKRGCL-LRKAEPYLAIRDFSIXXXXXXXXXNIMSYMYRGILYATTKQFSEAIVDFEVVICFNKDMCFAH---VNLGLI---------YFEKGDFEKSVKYMTSGLAADPTYIRAYPCRAEAYFQMNKYEDAIKDINRAIHLFPDRSNFYMLRGDFYLAMGKMEMAAICVRQAAEI 2605
P + + +L GT Q DAL + + DPNNYL Y++R + L + AI D S SLLL+ + I + R LY + SEA D +++ + A VN+G I Y+E FE ++ Y+ + RA +Y + + AI D A+ L D + + G + + + +R+ ++
Sbjct: 28 PGDVDKYLQTGTRLLAAGQLLDALVQYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNF--IPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKL 242 The following BLAST results are available for this feature:
BLAST of TPR_REGION domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TPR_REGION domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 4
BLAST of TPR_REGION domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of TPR_REGION domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TPR_REGION domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TPR_REGION domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TPR_REGION domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TPR_REGION domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TPR_REGION domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TPR_REGION domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of TPR_REGION domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TPR_REGION domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TPR_REGION domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TPR_REGION domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30000421 ID=SMED30000421|Name=TPR_REGION domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=4485bpback to top protein sequence of SMED30000421-orf-1 >SMED30000421-orf-1 ID=SMED30000421-orf-1|Name=SMED30000421-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1399bp MLNLTSEIEIVGTFISPSEPKIIDIWQPLAPRLFMSQNQVTNVLCPKYNPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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