mitfl-2 protein

Overview


Name	mitfl-2 protein (AGZ94933.1)
Smed ID	SMED30000409
Length (bp)	2389

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of mitfl-2 protein (SMED30000409) t-SNE clustered cells

Violin plots show distribution of expression levels for mitfl-2 protein (SMED30000409) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of mitfl-2 protein (SMED30000409) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for mitfl-2 protein (SMED30000409) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30000409

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 15

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
gut	SMED30000409	h1SMcG0011310	Contig2622	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
gut	SMED30000409	h1SMcG0011310	Contig2622	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30000409	h1SMcG0011310	Contig2622	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30000409	h1SMcG0011310	Contig2622	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
gut	SMED30000409	h1SMcG0022019	Contig2622	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
gut	SMED30000409	h1SMcG0022019	Contig2622	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30000409	h1SMcG0022019	Contig2622	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30000409	h1SMcG0022019	Contig2622	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
protonephridia	SMED30000409	h1SMcG0011310	dd_Smed_v4_7316_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30000409	h1SMcG0011310	dd_Smed_v4_7316_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30000409	h1SMcG0011310	dd_Smed_v4_7316_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
central nervous system	SMED30000409	h1SMcG0011310	KF487118	smed_ncbi_20240424	PMID:24173799 Cowles et al., 2013
progenitor cell	SMED30000409	h1SMcG0011310	KF487118	smed_ncbi_20240424	PMID:24173799 Cowles et al., 2013
stem cell	SMED30000409	h1SMcG0011310	KF487118	smed_ncbi_20240424	PMID:24173799 Cowles et al., 2013
parenchyma	SMED30000409	h1SMcG0011310	KF487118	smed_ncbi_20240424	PMID:24173799 Cowles et al., 2013

Note: Hover over icons to view figure legend

Homology

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BLAST of mitfl-2 protein vs. Ensembl Human
Match: USF1 (upstream transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12593])

HSP 1 Score: 61.6178 bits (148), Expect = 5.678e-10
Identity = 29/71 (40.85%), Postives = 48/71 (67.61%), Query Frame = 3

Query:  786 PEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            P+ +  +  RD  ++  HN +ER+RRD INN I +L +++P+    ST+S ++KGGIL  +  YIQ+L++S
Sbjct:  126 PKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQS 196

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BLAST of mitfl-2 protein vs. Ensembl Human
Match: USF1 (upstream transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12593])

HSP 1 Score: 63.1586 bits (152), Expect = 5.829e-10
Identity = 29/71 (40.85%), Postives = 48/71 (67.61%), Query Frame = 3

Query:  786 PEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            P+ +  +  RD  ++  HN +ER+RRD INN I +L +++P+    ST+S ++KGGIL  +  YIQ+L++S
Sbjct:  187 PKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQS 257

[Close]

Query:  786 PEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            P+ +  +  RD  ++  HN +ER+RRD INN I +L +++P+    ST+S ++KGGIL  +  YIQ+L++S
Sbjct:  187 PKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQS 257

[Close]

BLAST of mitfl-2 protein vs. Ensembl Human
Match: USF1 (upstream transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12593])

HSP 1 Score: 62.003 bits (149), Expect = 9.164e-10
Identity = 29/71 (40.85%), Postives = 48/71 (67.61%), Query Frame = 3

Query:  786 PEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            P+ +  +  RD  ++  HN +ER+RRD INN I +L +++P+    ST+S ++KGGIL  +  YIQ+L++S
Sbjct:  159 PKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQS 229

[Close]

BLAST of mitfl-2 protein vs. Ensembl Human
Match: TFE3 (transcription factor binding to IGHM enhancer 3 [Source:HGNC Symbol;Acc:HGNC:11752])

HSP 1 Score: 62.7734 bits (151), Expect = 1.860e-9
Identity = 41/98 (41.84%), Postives = 59/98 (60.20%), Query Frame = 3

Query:  702 SNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQE 995
            S    TP+ T S  N+ P  +  I   + E +    +++R KKD HN IER+RR  IN++I+ELG L+P+      E + NKG ILK SV YI++LQ+
Sbjct:  308 SQGVATPAITVS--NSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--SDPEMRWNKGTILKASVDYIRKLQK 401

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BLAST of mitfl-2 protein vs. Ensembl Celegans
Match: hlh-30 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86MJ3])

HSP 1 Score: 76.2554 bits (186), Expect = 3.096e-14
Identity = 41/101 (40.59%), Postives = 61/101 (60.40%), Query Frame = 3

Query:  807 WVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            + RDR KKD HN IER+RR  IN++I+ELGQ+LP+    S + K NKG ILK S  YI+ LQ+        Q++ +  E+    +   ++ L+++L   GV
Sbjct:  173 YYRDRRKKDIHNMIERRRRYNINDRIKELGQMLPKN--TSEDMKLNKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEMLARQGV 271

[Close]

BLAST of mitfl-2 protein vs. Ensembl Celegans
Match: hlh-30 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86MJ3])

HSP 1 Score: 76.2554 bits (186), Expect = 3.147e-14
Identity = 41/101 (40.59%), Postives = 61/101 (60.40%), Query Frame = 3

Query:  807 WVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            + RDR KKD HN IER+RR  IN++I+ELGQ+LP+    S + K NKG ILK S  YI+ LQ+        Q++ +  E+    +   ++ L+++L   GV
Sbjct:  182 YYRDRRKKDIHNMIERRRRYNINDRIKELGQMLPKN--TSEDMKLNKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEMLARQGV 280

[Close]

BLAST of mitfl-2 protein vs. Ensembl Celegans
Match: hlh-30 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86MJ3])

HSP 1 Score: 76.2554 bits (186), Expect = 3.349e-14
Identity = 41/101 (40.59%), Postives = 61/101 (60.40%), Query Frame = 3

Query:  807 WVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            + RDR KKD HN IER+RR  IN++I+ELGQ+LP+    S + K NKG ILK S  YI+ LQ+        Q++ +  E+    +   ++ L+++L   GV
Sbjct:  207 YYRDRRKKDIHNMIERRRRYNINDRIKELGQMLPKN--TSEDMKLNKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEMLARQGV 305

[Close]

BLAST of mitfl-2 protein vs. Ensembl Celegans
Match: hlh-30 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86MJ3])

HSP 1 Score: 75.0998 bits (183), Expect = 3.477e-14
Identity = 41/101 (40.59%), Postives = 61/101 (60.40%), Query Frame = 3

Query:  807 WVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            + RDR KKD HN IER+RR  IN++I+ELGQ+LP+    S + K NKG ILK S  YI+ LQ+        Q++ +  E+    +   ++ L+++L   GV
Sbjct:   95 YYRDRRKKDIHNMIERRRRYNINDRIKELGQMLPKN--TSEDMKLNKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEMLARQGV 193

[Close]

Query:  807 WVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            + RDR KKD HN IER+RR  IN++I+ELGQ+LP+    S + K NKG ILK S  YI+ LQ+        Q++ +  E+    +   ++ L+++L   GV
Sbjct:   95 YYRDRRKKDIHNMIERRRRYNINDRIKELGQMLPKN--TSEDMKLNKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEMLARQGV 193

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BLAST of mitfl-2 protein vs. Ensembl Fly
Match: Mitf (gene:FBgn0263112 transcript:FBtr0307326)

HSP 1 Score: 62.003 bits (149), Expect = 1.855e-9
Identity = 43/121 (35.54%), Postives = 65/121 (53.72%), Query Frame = 3

Query:  774 PSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKR----NKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQN 1124
            P  L + +     +DR KKD HN IER+RR  IN++I+ELG LLP+      E  R    NKG ILK+SV YI+ L+  ++ ++  +   +  E         I+ L+   KS+G+   +N
Sbjct:  384 PQNLTDAEMNALAKDRQKKDNHNMIERRRRFNINDRIKELGTLLPKGSDAFYEVVRDIRPNKGTILKSSVDYIKCLKHEVTRLRQNELRQRQVELQNRKLMSRIKELEMQAKSHGILLSEN 504

[Close]

BLAST of mitfl-2 protein vs. Ensembl Fly
Match: Mitf (gene:FBgn0263112 transcript:FBtr0307327)

HSP 1 Score: 62.003 bits (149), Expect = 1.855e-9
Identity = 43/121 (35.54%), Postives = 65/121 (53.72%), Query Frame = 3

Query:  774 PSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKR----NKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQN 1124
            P  L + +     +DR KKD HN IER+RR  IN++I+ELG LLP+      E  R    NKG ILK+SV YI+ L+  ++ ++  +   +  E         I+ L+   KS+G+   +N
Sbjct:  384 PQNLTDAEMNALAKDRQKKDNHNMIERRRRFNINDRIKELGTLLPKGSDAFYEVVRDIRPNKGTILKSSVDYIKCLKHEVTRLRQNELRQRQVELQNRKLMSRIKELEMQAKSHGILLSEN 504

[Close]

BLAST of mitfl-2 protein vs. Ensembl Fly
Match: Mitf (gene:FBgn0263112 transcript:FBtr0307328)

HSP 1 Score: 62.003 bits (149), Expect = 1.942e-9
Identity = 43/121 (35.54%), Postives = 65/121 (53.72%), Query Frame = 3

Query:  774 PSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKR----NKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQN 1124
            P  L + +     +DR KKD HN IER+RR  IN++I+ELG LLP+      E  R    NKG ILK+SV YI+ L+  ++ ++  +   +  E         I+ L+   KS+G+   +N
Sbjct:  491 PQNLTDAEMNALAKDRQKKDNHNMIERRRRFNINDRIKELGTLLPKGSDAFYEVVRDIRPNKGTILKSSVDYIKCLKHEVTRLRQNELRQRQVELQNRKLMSRIKELEMQAKSHGILLSEN 611

[Close]

BLAST of mitfl-2 protein vs. Ensembl Fly
Match: Mitf (gene:FBgn0263112 transcript:FBtr0307329)

HSP 1 Score: 61.6178 bits (148), Expect = 2.070e-9
Identity = 36/81 (44.44%), Postives = 49/81 (60.49%), Query Frame = 3

Query:  774 PSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKR----NKGGILKNSVIYIQQLQESIS 1004
            P  L + +     +DR KKD HN IER+RR  IN++I+ELG LLP+      E  R    NKG ILK+SV YI+ L+  ++
Sbjct:  358 PQNLTDAEMNALAKDRQKKDNHNMIERRRRFNINDRIKELGTLLPKGSDAFYEVVRDIRPNKGTILKSSVDYIKCLKHEVT 438

[Close]

BLAST of mitfl-2 protein vs. Ensembl Zebrafish
Match: mitfb (melanocyte inducing transcription factor b [Source:ZFIN;Acc:ZDB-GENE-010919-1])

HSP 1 Score: 69.3218 bits (168), Expect = 9.493e-12
Identity = 53/144 (36.81%), Postives = 77/144 (53.47%), Query Frame = 3

Query:  615 STSCPANMAN---PFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWV-RDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQ 1034
            S SCPANM +    F  T  P +M  +   + S+ ++  S  R             P G P E +++ + ++R KKD HN IER+RR  IN++I+ELG L+P+      + + NKG ILK SV YI++LQ      QH  KE +
Sbjct:  237 SNSCPANMTSVKREFSVTPSPALM--HMMDKPSSCSKFESYQR-------------PEGFPVEVEVRALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--NDPDMRWNKGTILKASVDYIRKLQRE----QHRTKELE 359

[Close]

BLAST of mitfl-2 protein vs. Ensembl Zebrafish
Match: mitfb (melanocyte inducing transcription factor b [Source:ZFIN;Acc:ZDB-GENE-010919-1])

HSP 1 Score: 68.1662 bits (165), Expect = 1.467e-11
Identity = 53/144 (36.81%), Postives = 77/144 (53.47%), Query Frame = 3

Query:  615 STSCPANMAN---PFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWV-RDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQ 1034
            S SCPANM +    F  T  P +M  +   + S+ ++  S  R             P G P E +++ + ++R KKD HN IER+RR  IN++I+ELG L+P+      + + NKG ILK SV YI++LQ      QH  KE +
Sbjct:  237 SNSCPANMTSVKREFSVTPSPALM--HMMDKPSSCSKFESYQR-------------PEGFPVEVEVRALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--NDPDMRWNKGTILKASVDYIRKLQRE----QHRTKELE 359

[Close]

BLAST of mitfl-2 protein vs. Ensembl Zebrafish
Match: tfe3b (transcription factor binding to IGHM enhancer 3b [Source:ZFIN;Acc:ZDB-GENE-010919-3])

HSP 1 Score: 65.4698 bits (158), Expect = 1.307e-10
Identity = 46/135 (34.07%), Postives = 71/135 (52.59%), Query Frame = 3

Query:  735 SSANNTPQIVTT--IPSGLP-------EEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVN 1112
            S    TP I  +   P+ LP       E +   ++++R KKD HN IER+RR  IN++I+ELG L+P+      E + NKG ILK SV YI++LQ+     + ++   +  E         IQ L+   + +G+N
Sbjct:  182 SPGMTTPTITVSNSCPADLPNIKREYTETEARAFMKERQKKDNHNLIERRRRFNINDRIKELGALIPKS--TDPEMRWNKGTILKASVDYIRKLQKEQQRAKEIEMRQKKLEQSNQALILRIQELEIQARHHGLN 314

[Close]

BLAST of mitfl-2 protein vs. Ensembl Zebrafish
Match: tfe3b (transcription factor binding to IGHM enhancer 3b [Source:ZFIN;Acc:ZDB-GENE-010919-3])

HSP 1 Score: 64.6994 bits (156), Expect = 1.738e-10
Identity = 40/96 (41.67%), Postives = 57/96 (59.38%), Query Frame = 3

Query:  735 SSANNTPQIVTT--IPSGLP-------EEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQE 995
            S    TP I  +   P+ LP       E +   ++++R KKD HN IER+RR  IN++I+ELG L+P+      E + NKG ILK SV YI++LQ+
Sbjct:  182 SPGMTTPTITVSNSCPADLPNIKREYTETEARAFMKERQKKDNHNLIERRRRFNINDRIKELGALIPKS--TDPEMRWNKGTILKASVDYIRKLQK 275

[Close]

BLAST of mitfl-2 protein vs. Ensembl Zebrafish
Match: usf1 (upstream transcription factor 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1072])

HSP 1 Score: 62.7734 bits (151), Expect = 1.965e-10
Identity = 34/106 (32.08%), Postives = 63/106 (59.43%), Query Frame = 3

Query:  813 RDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES-------ISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            RD  ++  HN +ER+RRD INN I +L + +P+    ST++ ++KGGIL  +  YIQ+L++S       ++ I+ L+ + Q+    +  +    Q L++ L+ +G+
Sbjct:  116 RDEKRRAQHNEVERRRRDKINNWIVQLSKTIPDCTIDSTKTGQSKGGILSKACDYIQELRQSNSRLGDELNSIERLRMDNQLLRQEVEDWKSKNQILRNQLRQHGI 221

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BLAST of mitfl-2 protein vs. Ensembl Xenopus
Match: tfeb (transcription factor EB [Source:NCBI gene;Acc:780105])

HSP 1 Score: 67.0106 bits (162), Expect = 5.863e-11
Identity = 40/83 (48.19%), Postives = 53/83 (63.86%), Query Frame = 3

Query:  807 WVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLIT 1055
             VR+R KKD HN IER+RR  IN++I+ELG L+P+   LS +++ NKG IL+ SV Y          I+H+QKE Q S  L T
Sbjct:  223 LVRERQKKDTHNMIERRRRFNINDRIKELGTLIPKTNELS-DTRWNKGTILRASVDY----------IKHMQKEQQKSRELET 294

[Close]

BLAST of mitfl-2 protein vs. Ensembl Xenopus
Match: usf2 (upstream transcription factor 2, c-fos interacting [Source:NCBI gene;Acc:493244])

HSP 1 Score: 60.4622 bits (145), Expect = 4.635e-9
Identity = 38/118 (32.20%), Postives = 64/118 (54.24%), Query Frame = 3

Query:  813 RDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKNLLQEWFDIH 1166
            RD  ++  HN +ER+RRD INN I +L +++P+    ST++  +KGGIL  +  YI++L+++   +Q   KEA+            +Q   DLL+      E++ N+  LL+     H
Sbjct:  214 RDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNTESTKTGASKGGILSKACDYIRELRQTNQRMQETYKEAE-----------RLQMDNDLLRQ---QIEEHKNENALLRAQLQQH 317

[Close]

BLAST of mitfl-2 protein vs. Ensembl Xenopus
Match: ipo9 (importin 9 [Source:Xenbase;Acc:XB-GENE-5960761])

HSP 1 Score: 61.2326 bits (147), Expect = 5.071e-9
Identity = 37/96 (38.54%), Postives = 54/96 (56.25%), Query Frame = 3

Query:  705 NNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQ 992
             N   P    + +N+ P  +  I     E +     ++R KKD HN IER+RR  IN++I+ELG L+P+      + + NKG ILK SV YI++LQ
Sbjct:  254 GNQGMPPPGLNVSNSCPANLPHIKREFTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--NDPDMRWNKGTILKASVDYIRKLQ 347

[Close]

BLAST of mitfl-2 protein vs. Ensembl Xenopus
Match: ipo9 (importin 9 [Source:Xenbase;Acc:XB-GENE-5960761])

HSP 1 Score: 60.8474 bits (146), Expect = 5.453e-9
Identity = 37/96 (38.54%), Postives = 54/96 (56.25%), Query Frame = 3

Query:  705 NNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQ 992
             N   P    + +N+ P  +  I     E +     ++R KKD HN IER+RR  IN++I+ELG L+P+      + + NKG ILK SV YI++LQ
Sbjct:  229 GNQGMPPPGLNVSNSCPANLPHIKREFTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--NDPDMRWNKGTILKASVDYIRKLQ 322

[Close]

BLAST of mitfl-2 protein vs. Ensembl Xenopus
Match: ipo9 (importin 9 [Source:Xenbase;Acc:XB-GENE-5960761])

HSP 1 Score: 58.9214 bits (141), Expect = 1.956e-8
Identity = 32/68 (47.06%), Postives = 45/68 (66.18%), Query Frame = 3

Query:  789 EEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQ 992
            E +     ++R KKD HN IER+RR  IN++I+ELG L+P+      + + NKG ILK SV YI++LQ
Sbjct:  229 ESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--NDPDMRWNKGTILKASVDYIRKLQ 294

[Close]

BLAST of mitfl-2 protein vs. Ensembl Mouse
Match: Usf1 (upstream transcription factor 1 [Source:MGI Symbol;Acc:MGI:99542])

HSP 1 Score: 63.1586 bits (152), Expect = 3.633e-10
Identity = 29/71 (40.85%), Postives = 48/71 (67.61%), Query Frame = 3

Query:  786 PEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            P+ +  +  RD  ++  HN +ER+RRD INN I +L +++P+    ST+S ++KGGIL  +  YIQ+L++S
Sbjct:  187 PKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQS 257

[Close]

BLAST of mitfl-2 protein vs. Ensembl Mouse
Match: Usf1 (upstream transcription factor 1 [Source:MGI Symbol;Acc:MGI:99542])

HSP 1 Score: 62.7734 bits (151), Expect = 5.111e-10
Identity = 29/71 (40.85%), Postives = 48/71 (67.61%), Query Frame = 3

Query:  786 PEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            P+ +  +  RD  ++  HN +ER+RRD INN I +L +++P+    ST+S ++KGGIL  +  YIQ+L++S
Sbjct:  187 PKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQS 257

[Close]

Query:  786 PEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            P+ +  +  RD  ++  HN +ER+RRD INN I +L +++P+    ST+S ++KGGIL  +  YIQ+L++S
Sbjct:  187 PKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQS 257

[Close]

BLAST of mitfl-2 protein vs. Ensembl Mouse
Match: Tfeb (transcription factor EB [Source:MGI Symbol;Acc:MGI:103270])

HSP 1 Score: 61.6178 bits (148), Expect = 1.489e-9
Identity = 37/100 (37.00%), Postives = 60/100 (60.00%), Query Frame = 3

Query:  810 VRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
             ++R KKD HN IER+RR  IN++I+ELG L+P+   L    + NKG ILK SV YI+++Q+ +   + L+  ++  E      +  IQ L+   + +G+
Sbjct:   89 AKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV--RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGL 186

[Close]

BLAST of mitfl-2 protein vs. Ensembl Mouse
Match: Tfe3 (transcription factor E3 [Source:MGI Symbol;Acc:MGI:98511])

HSP 1 Score: 62.003 bits (149), Expect = 1.771e-9
Identity = 41/98 (41.84%), Postives = 59/98 (60.20%), Query Frame = 3

Query:  702 SNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQE 995
            S    TP+ T S  N+ P  +  I   + E +    +++R KKD HN IER+RR  IN++I+ELG L+P+      E + NKG ILK SV YI++LQ+
Sbjct:  202 SQGVATPAITVS--NSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--NDPEMRWNKGTILKASVDYIRKLQK 295

[Close]

BLAST of mitfl-2 protein vs. UniProt/SwissProt
Match: sp|Q6XBT4|USF1_BOVIN (Upstream stimulatory factor 1 OS=Bos taurus OX=9913 GN=USF1 PE=2 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 2.466e-9
Identity = 29/71 (40.85%), Postives = 48/71 (67.61%), Query Frame = 3

Query:  786 PEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            P+ +  +  RD  ++  HN +ER+RRD INN I +L +++P+    ST+S ++KGGIL  +  YIQ+L++S
Sbjct:  187 PKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQS 257

[Close]

BLAST of mitfl-2 protein vs. UniProt/SwissProt
Match: sp|P22415|USF1_HUMAN (Upstream stimulatory factor 1 OS=Homo sapiens OX=9606 GN=USF1 PE=1 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 2.799e-9
Identity = 29/71 (40.85%), Postives = 48/71 (67.61%), Query Frame = 3

Query:  786 PEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            P+ +  +  RD  ++  HN +ER+RRD INN I +L +++P+    ST+S ++KGGIL  +  YIQ+L++S
Sbjct:  187 PKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQS 257

[Close]

BLAST of mitfl-2 protein vs. UniProt/SwissProt
Match: sp|Q61069|USF1_MOUSE (Upstream stimulatory factor 1 OS=Mus musculus OX=10090 GN=Usf1 PE=1 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 3.575e-9
Identity = 29/71 (40.85%), Postives = 48/71 (67.61%), Query Frame = 3

Query:  786 PEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            P+ +  +  RD  ++  HN +ER+RRD INN I +L +++P+    ST+S ++KGGIL  +  YIQ+L++S
Sbjct:  187 PKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQS 257

[Close]

BLAST of mitfl-2 protein vs. UniProt/SwissProt
Match: sp|Q05B92|TFE3_BOVIN (Transcription factor E3 OS=Bos taurus OX=9913 GN=TFE3 PE=2 SV=1)

HSP 1 Score: 63.5438 bits (153), Expect = 4.390e-9
Identity = 43/99 (43.43%), Postives = 61/99 (61.62%), Query Frame = 3

Query:  708 NNQ---TPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQE 995
            NNQ   TP+ T S  N+ P  +  I   + E +    +++R KKD HN IER+RR  IN++I+ELG L+P+      E + NKG ILK SV YI++LQ+
Sbjct:  305 NNQGVATPAITVS--NSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--SDPEMRWNKGTILKASVDYIRKLQK 399

[Close]

BLAST of mitfl-2 protein vs. UniProt/SwissProt
Match: sp|O02818|USF1_RABIT (Upstream stimulatory factor 1 OS=Oryctolagus cuniculus OX=9986 GN=USF1 PE=2 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 5.044e-9
Identity = 29/71 (40.85%), Postives = 47/71 (66.20%), Query Frame = 3

Query:  786 PEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            P+    +  RD  ++  HN +ER+RRD INN I +L +++P+    ST+S ++KGGIL  +  YIQ+L++S
Sbjct:  187 PKSAAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQS 257

[Close]

BLAST of mitfl-2 protein vs. TrEMBL
Match: U5YQE6 (Mitfl-2 protein (Fragment) OS=Schmidtea mediterranea OX=79327 GN=mitfl-2 PE=2 SV=1)

HSP 1 Score: 1232.62 bits (3188), Expect = 0.000e+0
Identity = 652/654 (99.69%), Postives = 653/654 (99.85%), Query Frame = 3

Query:  117 KSRTNAQQELMRQQIIEEERNILKHQNLKNLPQSVKFNKIITPSKNLVYSRDCLVKPXXXXXXXXXXXXKRQRSSSDVSQLKIESFSPTTKSPMDLAFSNLGNDHDVLDWNQIEPSITTTSDISPQEILEQITRSQNDSIPEGQMETGTEENDSIQDDQSVSSLKPSTSCPANMANPFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKNLLQEWFDIHQTNSHLLQKINAIQSTWTTENNHRDKLSVYTNYDDVSITENSVSAENILNSISIPREQTINXXXXXXXXTPITNYSSPITNTSSTVASNNRSRQTPVTNMNIIAVNSPQQFQSHIYGSSQPYVKSNFRMYEQSQSKPGITDSPVLSSILIGSGINNNGVKTFQDLQXXXXXXXXXXXXXXXVPDEPRISFFSHSSETNQGERYYLIPITKAKNLQLVTSEFKTSRGLVKVETDFSYNEDPVLSRIHSDSKNSSNRIQILNSFATTSLSHXXXXXVQNCIEISPEQIDNDDSLMGEFEFDDIPME 2078
            KSRTNAQQELMRQQIIEEERNILKHQNLKNLPQSVKFNKIITPSKNLVYSRDCLVKPNVTIVNNNSNISKRQRSSSDVSQLKIESFSPTTKSPMDLAFSNLGNDHDVLDWNQIEPSITTTSDISPQEILEQITRSQNDSIPEGQMETGTEENDSIQDDQSVSSLKPSTSCPANMANPFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKNLLQEWFDIHQTNSHLLQKINAIQSTWTTENNHRDKLSVYTNYDDVSITENSVSAENILNSISIPREQTINSGGGSSSGTPITNYSSPITNTSSTVASNNR RQTPVTNMNII+VNSPQQFQSHIYGSSQPYVKSNFRMYEQSQSKPGITDSPVLSSILIGSGINNNGVKTFQDLQSLSKSNTTSTSHSNSVPDEPRISFFSHSSETNQGERYYLIPITKAKNLQLVTSEFKTSRGLVKVETDFSYNEDPVLSRIHSDSKNSSNRIQILNSFATTSLSHEEEEEVQNCIEISPEQIDNDDSLMGEFEFDDIPME
Sbjct:    1 KSRTNAQQELMRQQIIEEERNILKHQNLKNLPQSVKFNKIITPSKNLVYSRDCLVKPNVTIVNNNSNISKRQRSSSDVSQLKIESFSPTTKSPMDLAFSNLGNDHDVLDWNQIEPSITTTSDISPQEILEQITRSQNDSIPEGQMETGTEENDSIQDDQSVSSLKPSTSCPANMANPFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKNLLQEWFDIHQTNSHLLQKINAIQSTWTTENNHRDKLSVYTNYDDVSITENSVSAENILNSISIPREQTINSGGGSSSGTPITNYSSPITNTSSTVASNNRPRQTPVTNMNIISVNSPQQFQSHIYGSSQPYVKSNFRMYEQSQSKPGITDSPVLSSILIGSGINNNGVKTFQDLQSLSKSNTTSTSHSNSVPDEPRISFFSHSSETNQGERYYLIPITKAKNLQLVTSEFKTSRGLVKVETDFSYNEDPVLSRIHSDSKNSSNRIQILNSFATTSLSHEEEEEVQNCIEISPEQIDNDDSLMGEFEFDDIPME 654

[Close]

BLAST of mitfl-2 protein vs. TrEMBL
Match: G7Y7J8 (Transcription factor EB OS=Clonorchis sinensis OX=79923 GN=CLF_102233 PE=4 SV=1)

HSP 1 Score: 148.288 bits (373), Expect = 6.681e-33
Identity = 104/299 (34.78%), Postives = 153/299 (51.17%), Query Frame = 3

Query:  363 IESFSPTTKSPMDLAFSNLGNDH--DVLDWNQIEPSITTTSDISPQEILEQITR--SQNDSIPEGQMETGTEENDS--IQD----------DQSVSSLKPSTSCPANM---ANPFHATSGPTVMIKYQFSQKSNNNQTP---SSTRSSANNTPQIVTTIP--SGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLK-SNGVNYEQ--NINDKNLLQEWFDIHQTNS 1178
            + S S    SPM+  F+N+  +H  D +D N I PSI  ++ +   E L    +  S ND + +    TG  +     +QD           +  S +K S SCP ++    NP   +  P   +  Q     +        ++   S + T  + TT+   S  PEEQ+  WVRDR KKD HNRIERKRRDYIN QI ELG LLPE++F   + K+NKG ILKNSV +I  L+  +S +  +++E  ++  +I    K IQYL+++   S G N     N++    LQEW  +H+ N+
Sbjct:  214 LSSVSSDLNSPMESCFANILEEHGNDSIDLNSITPSIQFSTPVG-SEFLNYAGQHTSTNDRVHQVHCTTGQPQLGIRILQDYDTRQISPKLSEGSSPIKSSASCPTDVQGVLNPLGTSPLPVGSLGTQVGTSGSGGSLGGVSATDGGSGSGTALLFTTVSPMSRHPEEQRAAWVRDRTKKDSHNRIERKRRDYINCQISELGNLLPEEMFRDGDCKKNKGSILKNSVEFICLLRAELSQLSEVRRETNLAAKVIGQLIKRIQYLEEVCGISQGSNTLDLGNLDYHRCLQEWLLLHERNT 511

[Close]

BLAST of mitfl-2 protein vs. TrEMBL
Match: A0A3R7CHW0 (Transcription factor EB OS=Clonorchis sinensis OX=79923 GN=Tfeb PE=4 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 8.408e-33
Identity = 104/299 (34.78%), Postives = 153/299 (51.17%), Query Frame = 3

Query:  363 IESFSPTTKSPMDLAFSNLGNDH--DVLDWNQIEPSITTTSDISPQEILEQITR--SQNDSIPEGQMETGTEENDS--IQD----------DQSVSSLKPSTSCPANM---ANPFHATSGPTVMIKYQFSQKSNNNQTP---SSTRSSANNTPQIVTTIP--SGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLK-SNGVNYEQ--NINDKNLLQEWFDIHQTNS 1178
            + S S    SPM+  F+N+  +H  D +D N I PSI  ++ +   E L    +  S ND + +    TG  +     +QD           +  S +K S SCP ++    NP   +  P   +  Q     +        ++   S + T  + TT+   S  PEEQ+  WVRDR KKD HNRIERKRRDYIN QI ELG LLPE++F   + K+NKG ILKNSV +I  L+  +S +  +++E  ++  +I    K IQYL+++   S G N     N++    LQEW  +H+ N+
Sbjct:  214 LSSVSSDLNSPMESCFANILEEHGNDSIDLNSITPSIQFSTPVG-SEFLNYARQHTSTNDRVHQVHCTTGQPQLGIRILQDYDTRQISPKLSEGSSPIKSSASCPTDVQGVLNPLGTSPLPVGSLGTQVGTSGSGGSLGGVSATDGGSGSGTALLFTTVSPMSRHPEEQRAAWVRDRTKKDSHNRIERKRRDYINCQISELGNLLPEEMFRDGDCKKNKGSILKNSVEFICLLRAELSQLSEVRRETNLAAKVIGQLIKRIQYLEEVCGISQGSNTLDLGNLDYHRCLQEWLLLHERNT 511

[Close]

BLAST of mitfl-2 protein vs. TrEMBL
Match: A0A075AI01 (BHLH domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_02816 PE=4 SV=1)

HSP 1 Score: 144.436 bits (363), Expect = 1.180e-31
Identity = 104/299 (34.78%), Postives = 156/299 (52.17%), Query Frame = 3

Query:  363 IESFSPTTKSPMDLAFSNLGNDH--DVLDWNQIEPSITTTSDISPQEILEQITR--SQNDSIPE-----GQMETGT---EENDSIQDD----QSVSSLKPSTSCPANM---ANPFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANN---TPQIVTTIP--SGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLK-SNGVNYEQ--NINDKNLLQEWFDIHQTNS 1178
            + S S    SPM+  F+N+  +H  D +D N I PSI  ++ +   E L    +  S ND + +     GQ++ G    ++ D+ Q      +  S +K S SCP ++    NP   +  P   +  Q     +       + +   +   T  + TT+   S  PEEQ+  WVRDR KKD HNRIERKRRDYIN QI ELG LLPE++F   + K+NKG ILKNSV +I  L+  +S +  +++E  ++  +I    K IQYL+++   S G N     N++    LQEW  +H+ N+
Sbjct:  211 LSSVSSDLNSPMESCFANILEEHGNDSIDLNSITPSIQFSTPVG-SEFLNYARQHTSTNDRVHQVPCTAGQLQLGIRILQDYDTRQISPKLSEGSSPIKSSASCPTDVQGVLNPLGTSPLPVGSLGTQVGTSGSGGSLGGVSGTDGGSGSGTALLFTTVSPMSRHPEEQRAAWVRDRTKKDSHNRIERKRRDYINCQISELGNLLPEEMFRDGDCKKNKGSILKNSVEFICLLRAELSQLSEVRRETNLAAKVIGQLIKRIQYLEEVCGISQGSNTLDLGNLDYHRCLQEWLLLHERNT 508

[Close]

BLAST of mitfl-2 protein vs. TrEMBL
Match: A0A4S2M3M1 (BHLH domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002952 PE=4 SV=1)

HSP 1 Score: 143.28 bits (360), Expect = 2.165e-31
Identity = 105/299 (35.12%), Postives = 155/299 (51.84%), Query Frame = 3

Query:  363 IESFSPTTKSPMDLAFSNLGNDH--DVLDWNQIEPSITTTSDISPQEILEQITR--SQNDSIPE-----GQMETGT---EENDSIQDD----QSVSSLKPSTSCPANM---ANPFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANN---TPQIVTTIP--SGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLK-SNGVNYEQ--NINDKNLLQEWFDIHQTNS 1178
            + S S    SPM+  F+N+  +H  D +D N I PSI  ++ +   E L    +  S ND + +     GQ + G    ++ DS Q      +  S +K S SCP ++    NP   +  P   +  Q     +       + +   +   T  + TT+   S  PEEQ+  WVRDR KKD HNRIERKRRDYIN QI ELG LLPE++F   + K+NKG ILKNSV +I  L+  +S +  +++E  ++  +I    K IQYL+++   S G N     N++    LQEW  +H+ N+
Sbjct:  214 LSSVSSDLNSPMESCFANILEEHGNDSIDLNSITPSIQFSTPVG-SEFLNYARQHTSTNDRVHQVPCTAGQPQLGIRILQDYDSRQISPKLSEGSSPIKSSASCPTDVQGVLNPLGTSPLPVGSLGTQVGTSGSGGSLGGVSGTDGGSGSGTALLFTTVSPMSRHPEEQRAAWVRDRTKKDSHNRIERKRRDYINCQISELGNLLPEEMFRDGDCKKNKGSILKNSVEFICLLRAELSQLSEVRRETNLAAKVIGQLIKRIQYLEEVCGISQGSNTLDLGNLDYHRCLQEWLLLHERNT 511

[Close]

BLAST of mitfl-2 protein vs. Ensembl Cavefish
Match: tfe3a (transcription factor E3 [Source:NCBI gene;Acc:103028851])

HSP 1 Score: 67.781 bits (164), Expect = 2.398e-11
Identity = 45/117 (38.46%), Postives = 67/117 (57.26%), Query Frame = 3

Query:  807 WVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLIT----VFYKHIQYLQDLLKSNGVNYEQNINDKNLL 1145
             +++R KKD HN IER+RR  IN++I+ELG L+P K    +E + NKG ILK SV YI++LQ+     QH  KE ++ +  +          IQ L+   + +G+   Q  +D  LL
Sbjct:  333 LIKERQKKDNHNLIERRRRFNINDRIKELGALVP-KSSDPSEMRWNKGTILKASVDYIRKLQKE----QHRAKEMELRQKKLEHANRTLLLRIQELEMQARVHGIASTQG-SDSTLL 443

[Close]

BLAST of mitfl-2 protein vs. Ensembl Cavefish
Match: mitfa (melanocyte inducing transcription factor a [Source:ZFIN;Acc:ZDB-GENE-990910-11])

HSP 1 Score: 66.6254 bits (161), Expect = 4.970e-11
Identity = 37/74 (50.00%), Postives = 52/74 (70.27%), Query Frame = 3

Query:  774 PSGLPEEQKLQ-WVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQ 992
            P GLP E +++  V++R KKD HN IER+RR  IN++I+ELG L+P+      + + NKG ILK SV YI++LQ
Sbjct:  171 PEGLPVEAEVRAMVKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--NDPDMRWNKGTILKASVDYIRKLQ 242

[Close]

BLAST of mitfl-2 protein vs. Ensembl Cavefish
Match: tfe3b (transcription factor binding to IGHM enhancer 3b [Source:ZFIN;Acc:ZDB-GENE-010919-3])

HSP 1 Score: 65.0846 bits (157), Expect = 1.461e-10
Identity = 40/93 (43.01%), Postives = 60/93 (64.52%), Query Frame = 3

Query:  717 TPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQE 995
            TP+ T S  N+ P  +  I + L + +    +++R KKD HN IER+RR  IN++I+ELG L+P+   +  E + NKG ILK SV YI++LQ+
Sbjct:  247 TPTITVS--NSCPADLPKIKTELTDVEAKALMKERQKKDNHNLIERRRRFNINDRIKELGALIPKS--VDPEMRWNKGTILKASVDYIRKLQK 335

[Close]

BLAST of mitfl-2 protein vs. Ensembl Cavefish
Match: usf1 (upstream transcription factor 1 [Source:NCBI gene;Acc:103024707])

HSP 1 Score: 61.6178 bits (148), Expect = 9.669e-10
Identity = 32/106 (30.19%), Postives = 61/106 (57.55%), Query Frame = 3

Query:  813 RDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQ-------ESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            RD  ++  HN +ER+RRD INN I +L + +P+    +T++ ++KGGIL  +  YIQ+L+       E +  ++ L+ + Q+    +  +    Q L++ L+ +G+
Sbjct:  195 RDDKRRAQHNEVERRRRDKINNWIVQLSKTIPDCTLDATKTGQSKGGILSKACDYIQELRQNNNRLGEELGMLERLRMDNQLLRQEVEDWKSKNQILRNQLRQHGI 300

[Close]

BLAST of mitfl-2 protein vs. Ensembl Cavefish
Match: usf1 (upstream transcription factor 1 [Source:NCBI gene;Acc:103024707])

HSP 1 Score: 60.8474 bits (146), Expect = 1.181e-9
Identity = 32/106 (30.19%), Postives = 61/106 (57.55%), Query Frame = 3

Query:  813 RDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQ-------ESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            RD  ++  HN +ER+RRD INN I +L + +P+    +T++ ++KGGIL  +  YIQ+L+       E +  ++ L+ + Q+    +  +    Q L++ L+ +G+
Sbjct:  174 RDDKRRAQHNEVERRRRDKINNWIVQLSKTIPDCTLDATKTGQSKGGILSKACDYIQELRQNNNRLGEELGMLERLRMDNQLLRQEVEDWKSKNQILRNQLRQHGI 279

[Close]

BLAST of mitfl-2 protein vs. Ensembl Sea Lamprey
Match: USF2 (upstream transcription factor 2, c-fos interacting [Source:HGNC Symbol;Acc:HGNC:12594])

HSP 1 Score: 61.2326 bits (147), Expect = 9.925e-11
Identity = 54/189 (28.57%), Postives = 92/189 (48.68%), Query Frame = 3

Query:  546 QMETGTEEND-SIQDDQSVSSLKPSTSCPANMANPFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEA---QISENLITVFYKHIQYLQDLLKS 1100
            QM+ GT   D S  DD +  ++          A  F+  S     I+YQF  +S++ Q            P    T P   P+ +  +  RD  ++  HN +ER+RRD INN I EL + +P+     T+S ++KGG+L  +  YIQ+L+++   ++   KEA   Q+   L+   ++ ++    LL++
Sbjct:   34 QMQEGTSAGDGSGADDHTAVAI-----ASVQQATAFNDPS-----IQYQFRTESSDGQ-------GGAQRPIAPRTHPY-TPKLEGPRTPRDERRRAQHNEVERRRRDKINNWIVELSKYIPDCANDHTKSVQSKGGVLSKACEYIQELRQTNQRMEEELKEAERTQLEHELLMQQFEELKNESALLRT 204

[Close]

BLAST of mitfl-2 protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001122.1 (pep scaffold:Pmarinus_7.0:GL489212:1806:7231:1 gene:ENSPMAG00000001002.1 transcript:ENSPMAT00000001122.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.077 bits (144), Expect = 7.403e-10
Identity = 39/93 (41.94%), Postives = 58/93 (62.37%), Query Frame = 3

Query:  717 TPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQE 995
            T SS  ++ +N  Q VT       E +    V++R KKD HN IER+RR  IN++I+ELG L+P+      +++ NKG ILK SV YI+++Q+
Sbjct:  245 TSSSCPATLDNVKQEVT-------EVEARAIVKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--SDPDTRWNKGTILKASVDYIRRMQK 328

[Close]

BLAST of mitfl-2 protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001124.1 (pep scaffold:Pmarinus_7.0:GL489212:1887:7231:1 gene:ENSPMAG00000001002.1 transcript:ENSPMAT00000001124.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.6918 bits (143), Expect = 9.418e-10
Identity = 31/62 (50.00%), Postives = 46/62 (74.19%), Query Frame = 3

Query:  810 VRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQE 995
            V++R KKD HN IER+RR  IN++I+ELG L+P+      +++ NKG ILK SV YI+++Q+
Sbjct:  255 VKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--SDPDTRWNKGTILKASVDYIRRMQK 314

[Close]

BLAST of mitfl-2 protein vs. Ensembl Sea Lamprey
Match: USF2 (upstream transcription factor 2, c-fos interacting [Source:HGNC Symbol;Acc:HGNC:12594])

HSP 1 Score: 58.9214 bits (141), Expect = 1.861e-9
Identity = 33/99 (33.33%), Postives = 59/99 (59.60%), Query Frame = 3

Query:  813 RDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEA---QISENLITVFYKHIQYLQDLLKS 1100
            RD  ++  HN +ER+RRD INN I EL + +P+     T+S ++KGG+L  +  YIQ+L+++   ++   KEA   Q+   L+   ++ ++    LL++
Sbjct:  235 RDERRRAQHNEVERRRRDKINNWIVELSKYIPDCANDHTKSVQSKGGVLSKACEYIQELRQTNQRMEEELKEAERTQLEHELLMQQFEELKNESALLRT 333

[Close]

BLAST of mitfl-2 protein vs. Ensembl Sea Lamprey
Match: mitfa (melanocyte inducing transcription factor a [Source:ZFIN;Acc:ZDB-GENE-990910-11])

HSP 1 Score: 56.9954 bits (136), Expect = 2.649e-9
Identity = 38/108 (35.19%), Postives = 63/108 (58.33%), Query Frame = 3

Query:  786 PEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            PE + L   ++R KKD HN IER+RR  IN++I+ELG L+P+      + + NKG ILK SV YI++LQ+    ++ ++   +  E         +Q L+   +++G+
Sbjct:    2 PEVRAL--AKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--NDPDMRWNKGTILKASVDYIRRLQKEQQRVKEMENRQRRLEQTNRGLIMRMQELEMQARAHGL 105

[Close]

BLAST of mitfl-2 protein vs. Ensembl Yeast
Match: RTG3 (bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways; forms a complex with another bHLH/Zip protein, Rtg1p, to activate the pathways; target of Hog1p [Source:SGD;Acc:S000000199])

HSP 1 Score: 62.003 bits (149), Expect = 1.768e-10
Identity = 38/94 (40.43%), Postives = 53/94 (56.38%), Query Frame = 3

Query:  726 STRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLF----LSTESKRNKGGILKNSVIYIQQLQE 995
            S+  + N  P  V  I  GL  ++KL     R K++ HN +ER+RR+ I  +I+ELGQL+P  L     L  + K NKG IL  +V Y+Q L E
Sbjct:  258 SSNMTENIGPGSVPKILGGLTSDEKL-----RRKREFHNAVERRRRELIKQKIKELGQLVPPSLLNYDDLGKQIKPNKGIILDRTVEYLQYLAE 346

[Close]

BLAST of mitfl-2 protein vs. Ensembl Yeast
Match: CBF1 (Basic helix-loop-helix (bHLH) protein; forms homodimer to bind E-box consensus sequence CACGTG present at MET gene promoters and centromere DNA element I (CDEI); affects nucleosome positioning at this motif; associates with other transcription factors such as Met4p and Isw1p to mediate transcriptional activation or repression; associates with kinetochore proteins, required for chromosome segregation; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003821])

HSP 1 Score: 52.7582 bits (125), Expect = 1.048e-7
Identity = 38/120 (31.67%), Postives = 59/120 (49.17%), Query Frame = 3

Query:  804 QWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISC------IQHLQKE------AQISENL---ITVFYKHIQYLQDLLKSNGVNYE 1118
            +W + R  KD H  +ER+RR+ IN  I  L  LLP +       + +K  IL  +  YIQ+L+E+         +Q L  E      A  +E L   +   YK I+Y++ +L+  G+ YE
Sbjct:  218 EWKKQR--KDSHKEVERRRRENINTAINVLSDLLPVR-------ESSKAAILACAAEYIQKLKETDEANIEKWTLQKLLSEQNASQLASANEKLQEELGNAYKEIEYMKRVLRKEGIEYE 328

[Close]

BLAST of mitfl-2 protein vs. Ensembl Nematostella
Match: EDO44411 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVM3])

HSP 1 Score: 73.9442 bits (180), Expect = 8.407e-14
Identity = 46/130 (35.38%), Postives = 74/130 (56.92%), Query Frame = 3

Query:  744 NNTPQIVTTIPSGLPE---EQKL-----QWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            N TP +    PS  P    E  +        RDR KKD HN IER+RR  IN++I+ELG +LP++     +S++NKG ILK SV YI+ L++ +  ++ +++E +  E L       +Q L+   +++G+
Sbjct:  242 NFTPMVQNAAPSSCPAVLNEPGISMDPNMLARDRQKKDNHNMIERRRRFNINDRIKELGTMLPKQ---DPDSRQNKGTILKASVDYIRNLKKDVDKMKLIEEEKRQLEMLNRKLLLRVQELEMHARAHGI 368

[Close]

BLAST of mitfl-2 protein vs. Ensembl Nematostella
Match: EDO39334 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAA2])

HSP 1 Score: 55.4546 bits (132), Expect = 1.990e-8
Identity = 32/95 (33.68%), Postives = 52/95 (54.74%), Query Frame = 3

Query:  720 PSSTRSSANNTPQIVTTI--PSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            P + RS A  T Q+ + +  P G          RD  ++  HN +ER+RRD IN  I +L +++P+     T++ ++KGGIL  +V YI  L+ +
Sbjct:  103 PGAQRSIAPRTHQLGSKLEGPRG---------ARDEKRRATHNEVERRRRDKINGWITKLAKVVPDCSSDQTKTGQSKGGILAKTVDYITDLRAA 188

[Close]

BLAST of mitfl-2 protein vs. Ensembl Nematostella
Match: EDO28110 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7E1])

HSP 1 Score: 49.2914 bits (116), Expect = 4.561e-7
Identity = 24/62 (38.71%), Postives = 40/62 (64.52%), Query Frame = 3

Query:  813 RDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQES 998
            RD  ++  HN +ER+RRD IN  I +L +++P+     T++ ++KGGIL  +V YI  L+ +
Sbjct:   21 RDEKRRATHNEVERRRRDKINGWITKLAKVVPDCSSDQTKTGQSKGGILAKTVDYITDLRAA 82

[Close]

BLAST of mitfl-2 protein vs. Ensembl Medaka
Match: ENSORLT00000031443.1 (transcription factor E3 [Source:NCBI gene;Acc:101174799])

HSP 1 Score: 68.1662 bits (165), Expect = 1.516e-11
Identity = 48/148 (32.43%), Postives = 81/148 (54.73%), Query Frame = 3

Query:  702 SNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKNLL 1145
            S   + PS+  S  N+ P  +  I   L E++    ++DR KK+ HN IER+RR  IN++I+ELG L+P+      E++ NKG ILK SV YI++LQ+     + L++  +  E+        IQ L+   + +G+    +++ +  L
Sbjct:  214 SGGQEVPSAAIS--NSCPANLHVIKKELSEDEAKALMKDRQKKNNHNLIERRRRFNINDRIKELGVLIPKS--SDMEARWNKGTILKASVDYIRKLQKDQQRARDLEERQKKLESTNRFLLLRIQELEQQARQHGLLSSSSVDPQTFL 357

[Close]

BLAST of mitfl-2 protein vs. Ensembl Medaka
Match: MITF (microphthalmia-associated transcription factor [Source:NCBI gene;Acc:101165733])

HSP 1 Score: 62.7734 bits (151), Expect = 9.571e-10
Identity = 40/112 (35.71%), Postives = 62/112 (55.36%), Query Frame = 3

Query:  774 PSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            P G P  +     ++R KKD HN IER+RR  IN++I+ELG L+P+      + + NKG ILK SV YI++LQ      + L+   +  E+        IQ L+   +++G+
Sbjct:  282 PEGFPVAEVRALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLMLRIQELEMQARAHGL 391

[Close]

BLAST of mitfl-2 protein vs. Ensembl Medaka
Match: MITF (microphthalmia-associated transcription factor [Source:NCBI gene;Acc:101165733])

HSP 1 Score: 62.3882 bits (150), Expect = 9.724e-10
Identity = 50/169 (29.59%), Postives = 84/169 (49.70%), Query Frame = 3

Query:  615 STSCPANMAN---PFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWV-RDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            S SCP N+ N    +  +  P +M  +   +  +  +  +  R             P G P E +++ + ++R KKD HN IER+RR  IN++I+ELG L+P+      + + NKG ILK SV YI++LQ      + L+   +  E+        IQ L+   +++G+
Sbjct:  191 SNSCPPNLPNIKREYSVSQSPAIM--HMLDKSGSCGKFDTYQR-------------PEGFPVEAEVRALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLMLRIQELEMQARAHGL 342

[Close]

BLAST of mitfl-2 protein vs. Ensembl Medaka
Match: MITF (microphthalmia-associated transcription factor [Source:NCBI gene;Acc:101165733])

HSP 1 Score: 62.3882 bits (150), Expect = 1.191e-9
Identity = 41/113 (36.28%), Postives = 66/113 (58.41%), Query Frame = 3

Query:  774 PSGLPEEQKLQWV-RDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            P G P E +++ + ++R KKD HN IER+RR  IN++I+ELG L+P+      + + NKG ILK SV YI++LQ      + L+   +  E+        IQ L+   +++G+
Sbjct:  264 PEGFPVEAEVRALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLMLRIQELEMQARAHGL 374

[Close]

BLAST of mitfl-2 protein vs. Ensembl Medaka
Match: MITF (microphthalmia-associated transcription factor [Source:NCBI gene;Acc:101165733])

HSP 1 Score: 62.003 bits (149), Expect = 1.347e-9
Identity = 50/169 (29.59%), Postives = 84/169 (49.70%), Query Frame = 3

Query:  615 STSCPANMAN---PFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWV-RDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGV 1109
            S SCP N+ N    +  +  P +M  +   +  +  +  +  R             P G P E +++ + ++R KKD HN IER+RR  IN++I+ELG L+P+      + + NKG ILK SV YI++LQ      + L+   +  E+        IQ L+   +++G+
Sbjct:  139 SNSCPPNLPNIKREYSVSQSPAIM--HMLDKSGSCGKFDTYQR-------------PEGFPVEAEVRALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS--NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLMLRIQELEMQARAHGL 290

[Close]

BLAST of mitfl-2 protein vs. Planmine SMEST
Match: SMESG000077129.1 (SMESG000077129.1)

HSP 1 Score: 1241.1 bits (3210), Expect = 0.000e+0
Identity = 655/655 (100.00%), Postives = 655/655 (100.00%), Query Frame = 3

Query:  114 MKSRTNAQQELMRQQIIEEERNILKHQNLKNLPQSVKFNKIITPSKNLVYSRDCLVKPXXXXXXXXXXXXKRQRSSSDVSQLKIESFSPTTKSPMDLAFSNLGNDHDVLDWNQIEPSITTTSDISPQEILEQITRSQNDSIPEGQMETGTEENDSIQDDQSVSSLKPSTSCPANMANPFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKNLLQEWFDIHQTNSHLLQKINAIQSTWTTENNHRDKLSVYTNYDDVSITENSVSAENILNSISIPREQTINXXXXXXXXTPITNYSSPITNTSSTVASNNRSRQTPVTNMNIIAVNSPQQFQSHIYGSSQPYVKSNFRMYEQSQSKPGITDSPVLSSILIGSGINNNGVKTFQDLQXXXXXXXXXXXXXXXVPDEPRISFFSHSSETNQGERYYLIPITKAKNLQLVTSEFKTSRGLVKVETDFSYNEDPVLSRIHSDSKNSSNRIQILNSFATTSLSHXXXXXVQNCIEISPEQIDNDDSLMGEFEFDDIPME 2078
            MKSRTNAQQELMRQQIIEEERNILKHQNLKNLPQSVKFNKIITPSKNLVYSRDCLVKPNVTIVNNNSNISKRQRSSSDVSQLKIESFSPTTKSPMDLAFSNLGNDHDVLDWNQIEPSITTTSDISPQEILEQITRSQNDSIPEGQMETGTEENDSIQDDQSVSSLKPSTSCPANMANPFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKNLLQEWFDIHQTNSHLLQKINAIQSTWTTENNHRDKLSVYTNYDDVSITENSVSAENILNSISIPREQTINSGGGSSSGTPITNYSSPITNTSSTVASNNRSRQTPVTNMNIIAVNSPQQFQSHIYGSSQPYVKSNFRMYEQSQSKPGITDSPVLSSILIGSGINNNGVKTFQDLQSLSKSNTTSTSHSNSVPDEPRISFFSHSSETNQGERYYLIPITKAKNLQLVTSEFKTSRGLVKVETDFSYNEDPVLSRIHSDSKNSSNRIQILNSFATTSLSHEEEEEVQNCIEISPEQIDNDDSLMGEFEFDDIPME
Sbjct:    1 MKSRTNAQQELMRQQIIEEERNILKHQNLKNLPQSVKFNKIITPSKNLVYSRDCLVKPNVTIVNNNSNISKRQRSSSDVSQLKIESFSPTTKSPMDLAFSNLGNDHDVLDWNQIEPSITTTSDISPQEILEQITRSQNDSIPEGQMETGTEENDSIQDDQSVSSLKPSTSCPANMANPFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKNLLQEWFDIHQTNSHLLQKINAIQSTWTTENNHRDKLSVYTNYDDVSITENSVSAENILNSISIPREQTINSGGGSSSGTPITNYSSPITNTSSTVASNNRSRQTPVTNMNIIAVNSPQQFQSHIYGSSQPYVKSNFRMYEQSQSKPGITDSPVLSSILIGSGINNNGVKTFQDLQSLSKSNTTSTSHSNSVPDEPRISFFSHSSETNQGERYYLIPITKAKNLQLVTSEFKTSRGLVKVETDFSYNEDPVLSRIHSDSKNSSNRIQILNSFATTSLSHEEEEEVQNCIEISPEQIDNDDSLMGEFEFDDIPME 655

[Close]

BLAST of mitfl-2 protein vs. Planmine SMEST
Match: SMESG000077129.1 (SMESG000077129.1)

HSP 1 Score: 471.855 bits (1213), Expect = 1.351e-162
Identity = 244/244 (100.00%), Postives = 244/244 (100.00%), Query Frame = 3

Query:  114 MKSRTNAQQELMRQQIIEEERNILKHQNLKNLPQSVKFNKIITPSKNLVYSRDCLVKPXXXXXXXXXXXXKRQRSSSDVSQLKIESFSPTTKSPMDLAFSNLGNDHDVLDWNQIEPSITTTSDISPQEILEQITRSQNDSIPEGQMETGTEENDSIQDDQSVSSLKPSTSCPANMANPFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNR 845
            MKSRTNAQQELMRQQIIEEERNILKHQNLKNLPQSVKFNKIITPSKNLVYSRDCLVKPNVTIVNNNSNISKRQRSSSDVSQLKIESFSPTTKSPMDLAFSNLGNDHDVLDWNQIEPSITTTSDISPQEILEQITRSQNDSIPEGQMETGTEENDSIQDDQSVSSLKPSTSCPANMANPFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNR
Sbjct:    1 MKSRTNAQQELMRQQIIEEERNILKHQNLKNLPQSVKFNKIITPSKNLVYSRDCLVKPNVTIVNNNSNISKRQRSSSDVSQLKIESFSPTTKSPMDLAFSNLGNDHDVLDWNQIEPSITTTSDISPQEILEQITRSQNDSIPEGQMETGTEENDSIQDDQSVSSLKPSTSCPANMANPFHATSGPTVMIKYQFSQKSNNNQTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNR 244

[Close]

BLAST of mitfl-2 protein vs. Planmine SMEST
Match: SMESG000051880.1 (SMESG000051880.1)

HSP 1 Score: 98.5969 bits (244), Expect = 1.546e-21
Identity = 58/154 (37.66%), Postives = 93/154 (60.39%), Query Frame = 3

Query:  738 SANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKNLLQEWFD---IHQTNSHLLQ 1190
            S+ N P   ++   G  +   L+  +DRNKK+ HNRIERKRRDYIN+QI ELG+L+P ++    ESK+NKG ILKNSV Y+ +L+   + I +  KE +++  L+  + K  Q L++ +K+       +I+ +NL   + +   +H+ N  + Q
Sbjct:  171 SSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYSTTTNSIDSQNLATNYHNYLLLHEQNQKIYQ 324

[Close]

BLAST of mitfl-2 protein vs. Planmine SMEST
Match: SMESG000051880.1 (SMESG000051880.1)

HSP 1 Score: 98.2117 bits (243), Expect = 2.311e-21
Identity = 58/154 (37.66%), Postives = 93/154 (60.39%), Query Frame = 3

Query:  738 SANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKNLLQEWFD---IHQTNSHLLQ 1190
            S+ N P   ++   G  +   L+  +DRNKK+ HNRIERKRRDYIN+QI ELG+L+P ++    ESK+NKG ILKNSV Y+ +L+   + I +  KE +++  L+  + K  Q L++ +K+       +I+ +NL   + +   +H+ N  + Q
Sbjct:  184 SSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYSTTTNSIDSQNLATNYHNYLLLHEQNQKIYQ 337

[Close]

BLAST of mitfl-2 protein vs. Planmine SMEST
Match: SMESG000009137.1 (SMESG000009137.1)

HSP 1 Score: 92.4337 bits (228), Expect = 1.250e-19
Identity = 57/138 (41.30%), Postives = 85/138 (61.59%), Query Frame = 3

Query:  804 QWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYI--QQLQESIS--CIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKN---LLQEWFDIHQTNSHLLQKI 1196
            Q ++D++KK+ HNR+ERKRRD+IN QIQ+L +LLP + FL+ + K NKG ILKNSV YI   +L E I+   I   +  A++  +LI+  Y  +   Q  +  N +NY     + +   L+ +W+ IHQ N  LLQ+ 
Sbjct:   90 QLIKDKHKKETHNRVERKRRDFINCQIQKLAELLPTEFFLNCDLKMNKGVILKNSVEYITSMKLVEQINHQLIHENELGAKLIRSLISSNYTDLNCSQLSINEN-LNYGAGNEEPDIGILINQWYAIHQDNKQLLQQF 226

The following BLAST results are available for this feature:

BLAST of mitfl-2 protein vs. Ensembl Human
BLAST of mitfl-2 protein vs. Ensembl Celegans
BLAST of mitfl-2 protein vs. Ensembl Fly
BLAST of mitfl-2 protein vs. Ensembl Zebrafish
BLAST of mitfl-2 protein vs. Ensembl Xenopus
BLAST of mitfl-2 protein vs. Ensembl Mouse
BLAST of mitfl-2 protein vs. UniProt/SwissProt
BLAST of mitfl-2 protein vs. TrEMBL
BLAST of mitfl-2 protein vs. Ensembl Cavefish
BLAST of mitfl-2 protein vs. Ensembl Sea Lamprey
BLAST of mitfl-2 protein vs. Ensembl Yeast
BLAST of mitfl-2 protein vs. Ensembl Nematostella
BLAST of mitfl-2 protein vs. Ensembl Medaka
BLAST of mitfl-2 protein vs. Planmine SMEST

BLAST of mitfl-2 protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
USF1	5.678e-10	40.85	upstream transcription factor 1 [Source:HGNC Symbo...	[more]
USF1	5.829e-10	40.85	upstream transcription factor 1 [Source:HGNC Symbo...	[more]
USF1	5.829e-10	40.85	upstream transcription factor 1 [Source:HGNC Symbo...	[more]
USF1	9.164e-10	40.85	upstream transcription factor 1 [Source:HGNC Symbo...	[more]
TFE3	1.860e-9	41.84	transcription factor binding to IGHM enhancer 3 [S...	[more]

BLAST of mitfl-2 protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hlh-30	3.096e-14	40.59	Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86...	[more]
hlh-30	3.147e-14	40.59	Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86...	[more]
hlh-30	3.349e-14	40.59	Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86...	[more]
hlh-30	3.477e-14	40.59	Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86...	[more]
hlh-30	3.477e-14	40.59	Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86...	[more]

BLAST of mitfl-2 protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Mitf	1.855e-9	35.54	gene:FBgn0263112 transcript:FBtr0307326	[more]
Mitf	1.855e-9	35.54	gene:FBgn0263112 transcript:FBtr0307327	[more]
Mitf	1.942e-9	35.54	gene:FBgn0263112 transcript:FBtr0307328	[more]
Mitf	2.070e-9	44.44	gene:FBgn0263112 transcript:FBtr0307329	[more]

BLAST of mitfl-2 protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mitfb	9.493e-12	36.81	melanocyte inducing transcription factor b [Source...	[more]
mitfb	1.467e-11	36.81	melanocyte inducing transcription factor b [Source...	[more]
tfe3b	1.307e-10	34.07	transcription factor binding to IGHM enhancer 3b [...	[more]
tfe3b	1.738e-10	41.67	transcription factor binding to IGHM enhancer 3b [...	[more]
usf1	1.965e-10	32.08	upstream transcription factor 1 [Source:ZFIN;Acc:Z...	[more]

BLAST of mitfl-2 protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfeb	5.863e-11	48.19	transcription factor EB [Source:NCBI gene;Acc:7801...	[more]
usf2	4.635e-9	32.20	upstream transcription factor 2, c-fos interacting...	[more]
ipo9	5.071e-9	38.54	importin 9 [Source:Xenbase;Acc:XB-GENE-5960761]	[more]
ipo9	5.453e-9	38.54	importin 9 [Source:Xenbase;Acc:XB-GENE-5960761]	[more]
ipo9	1.956e-8	47.06	importin 9 [Source:Xenbase;Acc:XB-GENE-5960761]	[more]

BLAST of mitfl-2 protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Usf1	3.633e-10	40.85	upstream transcription factor 1 [Source:MGI Symbol...	[more]
Usf1	5.111e-10	40.85	upstream transcription factor 1 [Source:MGI Symbol...	[more]
Usf1	5.111e-10	40.85	upstream transcription factor 1 [Source:MGI Symbol...	[more]
Tfeb	1.489e-9	37.00	transcription factor EB [Source:MGI Symbol;Acc:MGI...	[more]
Tfe3	1.771e-9	41.84	transcription factor E3 [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of mitfl-2 protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q6XBT4\|USF1_BOVIN	2.466e-9	40.85	Upstream stimulatory factor 1 OS=Bos taurus OX=991...	[more]
sp\|P22415\|USF1_HUMAN	2.799e-9	40.85	Upstream stimulatory factor 1 OS=Homo sapiens OX=9...	[more]
sp\|Q61069\|USF1_MOUSE	3.575e-9	40.85	Upstream stimulatory factor 1 OS=Mus musculus OX=1...	[more]
sp\|Q05B92\|TFE3_BOVIN	4.390e-9	43.43	Transcription factor E3 OS=Bos taurus OX=9913 GN=T...	[more]
sp\|O02818\|USF1_RABIT	5.044e-9	40.85	Upstream stimulatory factor 1 OS=Oryctolagus cunic...	[more]

BLAST of mitfl-2 protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
U5YQE6	0.000e+0	99.69	Mitfl-2 protein (Fragment) OS=Schmidtea mediterran...	[more]
G7Y7J8	6.681e-33	34.78	Transcription factor EB OS=Clonorchis sinensis OX=...	[more]
A0A3R7CHW0	8.408e-33	34.78	Transcription factor EB OS=Clonorchis sinensis OX=...	[more]
A0A075AI01	1.180e-31	34.78	BHLH domain-containing protein OS=Opisthorchis viv...	[more]
A0A4S2M3M1	2.165e-31	35.12	BHLH domain-containing protein OS=Opisthorchis fel...	[more]

BLAST of mitfl-2 protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfe3a	2.398e-11	38.46	transcription factor E3 [Source:NCBI gene;Acc:1030...	[more]
mitfa	4.970e-11	50.00	melanocyte inducing transcription factor a [Source...	[more]
tfe3b	1.461e-10	43.01	transcription factor binding to IGHM enhancer 3b [...	[more]
usf1	9.669e-10	30.19	upstream transcription factor 1 [Source:NCBI gene;...	[more]
usf1	1.181e-9	30.19	upstream transcription factor 1 [Source:NCBI gene;...	[more]

BLAST of mitfl-2 protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
USF2	9.925e-11	28.57	upstream transcription factor 2, c-fos interacting...	[more]
ENSPMAT00000001122.1	7.403e-10	41.94	pep scaffold:Pmarinus_7.0:GL489212:1806:7231:1 gen...	[more]
ENSPMAT00000001124.1	9.418e-10	50.00	pep scaffold:Pmarinus_7.0:GL489212:1887:7231:1 gen...	[more]
USF2	1.861e-9	33.33	upstream transcription factor 2, c-fos interacting...	[more]
mitfa	2.649e-9	35.19	melanocyte inducing transcription factor a [Source...	[more]

BLAST of mitfl-2 protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
RTG3	1.768e-10	40.43	bHLH/Zip transcription factor for retrograde (RTG)...	[more]
CBF1	1.048e-7	31.67	Basic helix-loop-helix (bHLH) protein; forms homod...	[more]

BLAST of mitfl-2 protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3


Match Name	E-value	Identity	Description
EDO44411	8.407e-14	35.38	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39334	1.990e-8	33.68	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28110	4.561e-7	38.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of mitfl-2 protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000031443.1	1.516e-11	32.43	transcription factor E3 [Source:NCBI gene;Acc:1011...	[more]
MITF	9.571e-10	35.71	microphthalmia-associated transcription factor [So...	[more]
MITF	9.724e-10	29.59	microphthalmia-associated transcription factor [So...	[more]
MITF	1.191e-9	36.28	microphthalmia-associated transcription factor [So...	[more]
MITF	1.347e-9	29.59	microphthalmia-associated transcription factor [So...	[more]

BLAST of mitfl-2 protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000077129.1	0.000e+0	100.00	SMESG000077129.1	[more]
SMESG000077129.1	1.351e-162	100.00	SMESG000077129.1	[more]
SMESG000051880.1	1.546e-21	37.66	SMESG000051880.1	[more]
SMESG000051880.1	2.311e-21	37.66	SMESG000051880.1	[more]
SMESG000009137.1	1.250e-19	41.30	SMESG000009137.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30000409
GenBank	AGZ94933.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30000409 ID=SMED30000409|Name=mitfl-2 protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2389bp
TCTGAATGTGAAAATTGATTATTGCTTTGTTATAATAATTATATTTAATT
GTAAATTAATAAAATAAAACCTTAAATAAATAATTAAAAATCAAAATTTG
AATTAAATAATCCATGAAGTCTCGCACAAATGCTCAACAAGAATTAATGA
GACAACAGATTATAGAAGAAGAACGGAATATTCTAAAACATCAAAATTTG
AAAAATTTACCACAAAGTGTAAAGTTTAATAAAATAATAACTCCAAGTAA
GAATTTAGTCTACAGCCGTGATTGTTTGGTAAAGCCCAATGTTACAATCG
TTAATAACAACAGTAATATAAGTAAAAGGCAAAGATCATCCTCAGACGTA
TCTCAGCTGAAAATCGAATCATTTTCACCTACCACTAAATCACCGATGGA
TTTGGCATTTTCTAATCTTGGAAACGATCACGATGTTCTGGACTGGAATC
AAATTGAACCATCTATCACAACTACCTCAGATATTTCACCTCAAGAGATT
TTAGAGCAAATCACACGATCACAAAATGATTCGATTCCCGAAGGTCAAAT
GGAAACTGGAACCGAAGAGAATGATTCTATTCAAGACGATCAAAGCGTCA
GTTCATTAAAACCATCTACGTCTTGCCCGGCGAACATGGCTAATCCATTC
CATGCCACTTCTGGACCAACTGTGATGATTAAATACCAGTTTTCTCAAAA
ATCAAACAACAATCAAACACCTAGTTCAACTCGTTCTTCAGCCAATAACA
CCCCACAAATCGTCACCACAATTCCATCGGGTTTGCCAGAAGAACAGAAA
TTACAATGGGTTCGCGATCGCAACAAAAAAGATTGTCATAATCGAATCGA
AAGAAAGCGAAGAGATTATATAAATAATCAGATCCAAGAACTTGGTCAAT
TATTACCAGAGAAATTATTTTTAAGCACAGAATCCAAACGTAACAAAGGT
GGAATATTGAAAAACTCTGTGATTTATATTCAACAGTTACAAGAATCAAT
TTCTTGTATTCAGCATTTGCAAAAGGAAGCACAAATATCAGAAAATCTAA
TTACAGTGTTTTACAAGCATATTCAGTATTTACAAGATTTATTAAAATCT
AATGGAGTTAATTATGAGCAAAATATCAATGACAAGAATCTCTTGCAAGA
ATGGTTTGATATTCATCAAACCAACAGTCATTTATTGCAGAAAATAAATG
CTATTCAGTCAACTTGGACTACTGAAAATAATCACCGAGACAAATTGTCC
GTCTATACAAACTATGATGACGTCTCTATAACAGAAAATTCAGTATCAGC
AGAGAATATATTGAATTCAATTTCAATTCCTAGAGAGCAAACAATTAATA
GCGGGGGTGGCAGTAGTTCTGGAACTCCCATTACAAACTACAGCTCCCCT
ATTACAAATACCTCAAGTACAGTCGCTAGTAACAACAGATCTCGTCAGAC
TCCCGTGACAAACATGAATATCATTGCTGTAAATTCACCTCAACAATTTC
AATCTCACATTTACGGATCATCTCAACCATATGTAAAATCGAATTTCCGA
ATGTATGAGCAATCTCAATCGAAACCAGGGATTACCGATAGTCCAGTATT
AAGTTCAATACTTATTGGATCTGGTATTAATAACAATGGTGTGAAGACAT
TTCAAGATTTACAATCTCTCTCTAAAAGCAATACTACGTCTACTAGTCAC
AGCAATAGTGTCCCAGATGAACCTAGAATAAGTTTTTTTAGTCATTCATC
AGAAACAAATCAAGGTGAAAGGTATTACTTGATCCCGATAACTAAAGCTA
AAAACTTGCAACTTGTCACTAGTGAATTCAAAACCTCCAGGGGTTTAGTA
AAGGTGGAAACTGATTTTTCATACAATGAAGATCCCGTTCTAAGTAGAAT
ACATTCAGATTCAAAAAACAGTTCAAATAGAATTCAAATTTTAAATTCCT
TTGCCACAACATCATTAAGTCACGAAGAAGAAGAAGAAGTTCAAAATTGT
ATTGAAATATCACCCGAACAGATAGACAATGATGATTCACTGATGGGAGA
GTTCGAGTTTGACGACATTCCTATGGAATGACGAAAGATTTGTCTCAAAA
CCACTTCCAAAGAAAAATTAAGAAACTGTATATAAGATTTATCCCTGGTA
TTTGAGACCTCGATTCATCACAAGGATGGCAGTGTTTGTGTAACACGTTG
TTTCGTAAATCATCATTTTATTCATGTAATTAATTGACCACTGACGAGTA
CACAAATATTTGTGCTTTACTGATATTTTGTTTTCTTTGTATGTATTTAA
GACTGAACGATTCTAAAAGTAATTTTATAGACAGTTAATGTAATTTTGAC
CTATCCTTTCACTTCATGAACAGAAGTTTTCTATTGTGT

protein sequence of SMED30000409-orf-1

>SMED30000409-orf-1 ID=SMED30000409-orf-1|Name=SMED30000409-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=656bp
MKSRTNAQQELMRQQIIEEERNILKHQNLKNLPQSVKFNKIITPSKNLVY
SRDCLVKPNVTIVNNNSNISKRQRSSSDVSQLKIESFSPTTKSPMDLAFS
NLGNDHDVLDWNQIEPSITTTSDISPQEILEQITRSQNDSIPEGQMETGT
EENDSIQDDQSVSSLKPSTSCPANMANPFHATSGPTVMIKYQFSQKSNNN
QTPSSTRSSANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRR
DYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQ
HLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKNLLQEWFDI
HQTNSHLLQKINAIQSTWTTENNHRDKLSVYTNYDDVSITENSVSAENIL
NSISIPREQTINSGGGSSSGTPITNYSSPITNTSSTVASNNRSRQTPVTN
MNIIAVNSPQQFQSHIYGSSQPYVKSNFRMYEQSQSKPGITDSPVLSSIL
IGSGINNNGVKTFQDLQSLSKSNTTSTSHSNSVPDEPRISFFSHSSETNQ
GERYYLIPITKAKNLQLVTSEFKTSRGLVKVETDFSYNEDPVLSRIHSDS
KNSSNRIQILNSFATTSLSHEEEEEVQNCIEISPEQIDNDDSLMGEFEFD
DIPME*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000026	gut
PLANA:0000070	intestinal phagocyte
PLANA:0000099	neuron
PLANA:0000103	central nervous system
PLANA:0000120	progenitor cell
PLANA:0000121	stem cell
PLANA:0002032	epidermal cell
PLANA:0002142	parenchyma

Vocabulary: **INTERPRO**
Term	Definition
IPR036638	HLH_DNA-bd_sf
IPR011598	bHLH_dom

Vocabulary: **molecular function**
Term	Definition
GO:0046983	protein dimerization activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain	SMART	SM00353	finulus	coord: 243..298 e-value: 5.1E-9 score: 46.0
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain	PFAM	PF00010	HLH	coord: 239..293 e-value: 7.2E-13 score: 48.3
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain	PROSITE	PS50888	BHLH	coord: 237..292 score: 13.3
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain	CDD	cd00083	HLH	coord: 235..297 e-value: 2.88113E-10 score: 54.1423
IPR036638	Helix-loop-helix DNA-binding domain superfamily	GENE3D	G3DSA:4.10.280.10		coord: 234..296 e-value: 4.0E-18 score: 67.2
IPR036638	Helix-loop-helix DNA-binding domain superfamily	SUPERFAMILY	SSF47459	HLH, helix-loop-helix DNA-binding domain	coord: 235..295
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 136..170
None	No IPR available	PANTHER	PTHR46117:SF3	FI24210P1	coord: 17..308
None	No IPR available	PANTHER	PTHR46117	FAMILY NOT NAMED	coord: 17..308