Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30000377 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Human
Match: MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18957]) HSP 1 Score: 119.783 bits (299), Expect = 4.825e-27 Identity = 122/452 (26.99%), Postives = 185/452 (40.93%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P + T+LI I F + + I + P P I P N P F PA H S DST+ F P PD + +K+ I S + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 202 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------IGSETSLI--IHRGGFFS-PWKTPKPIMDRWENQGSPQTSLSAPAI----PQNLP-FPPALHRSSF--PDSTEAFDPRK-----------------------------PDPYELYEKSRAIYESPDYKELDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 599 HSP 2 Score: 55.4546 bits (132), Expect = 4.014e-7 Identity = 98/475 (20.63%), Postives = 168/475 (35.37%), Query Frame = 2
Query: 506 ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH-----------NPNYDMINFYLQKTEG-------------------GFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF----IPDTFYESKKTNTIKYS-----QPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
+ DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH N N+ + EG GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E + + +S S +++ + + + P + L L RQD + RQ P Y P D Q P P Y +T +Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 368 KELDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKR 820 HSP 3 Score: 53.5286 bits (127), Expect = 1.862e-6 Identity = 27/86 (31.40%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
LKK N GFG T++ D + L+VK++ DGPA + G ++ GD++ N++ ++G +V+K+F+ V +S+ L + +
Sbjct: 34 LSTTLKKSNMGFGFTIIGGDEPD--EFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCR 117
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Human
Match: MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18957]) HSP 1 Score: 119.783 bits (299), Expect = 5.042e-27 Identity = 122/452 (26.99%), Postives = 185/452 (40.93%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P + T+LI I F + + I + P P I P N P F PA H S DST+ F P PD + +K+ I S + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 202 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------IGSETSLI--IHRGGFFS-PWKTPKPIMDRWENQGSPQTSLSAPAI----PQNLP-FPPALHRSSF--PDSTEAFDPRK-----------------------------PDPYELYEKSRAIYESPDYKELDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 599 HSP 2 Score: 55.8398 bits (133), Expect = 3.357e-7 Identity = 98/475 (20.63%), Postives = 168/475 (35.37%), Query Frame = 2
Query: 506 ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH-----------NPNYDMINFYLQKTEG-------------------GFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF----IPDTFYESKKTNTIKYS-----QPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
+ DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH N N+ + EG GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E + + +S S +++ + + + P + L L RQD + RQ P Y P D Q P P Y +T +Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 368 KELDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKR 820 HSP 3 Score: 53.5286 bits (127), Expect = 1.726e-6 Identity = 27/86 (31.40%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
LKK N GFG T++ D + L+VK++ DGPA + G ++ GD++ N++ ++G +V+K+F+ V +S+ L + +
Sbjct: 34 LSTTLKKSNMGFGFTIIGGDEPD--EFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCR 117
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Human
Match: MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18957]) HSP 1 Score: 116.316 bits (290), Expect = 8.667e-26 Identity = 120/443 (27.09%), Postives = 184/443 (41.53%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
+++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P + T+LI I F + + I + P P I P N P F PA H S DST+ F P P Y + S++PD+ + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 439 ELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------IGSETSLI--IHRGGFFS-PWKTPKPIMDRWENQGSPQTSLSAPAI----PQNLP-FPPALHRSSF--PDSTEAFDPRK-------PDPYELYEKSRAIYESRRPDY--------------------KELDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 829 HSP 2 Score: 55.8398 bits (133), Expect = 4.099e-7 Identity = 98/475 (20.63%), Postives = 168/475 (35.37%), Query Frame = 2
Query: 506 ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH-----------NPNYDMINFYLQKTEG-------------------GFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF----IPDTFYESKKTNTIKYS-----QPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
+ DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH N N+ + EG GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E + + +S S +++ + + + P + L L RQD + RQ P Y P D Q P P Y +T +Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 598 KELDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKR 1050 HSP 3 Score: 53.5286 bits (127), Expect = 1.926e-6 Identity = 27/86 (31.40%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
LKK N GFG T++ D + L+VK++ DGPA + G ++ GD++ N++ ++G +V+K+F+ V +S+ L + +
Sbjct: 262 LSTTLKKSNMGFGFTIIGGDEPD--EFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCR 345
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Human
Match: MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18957]) HSP 1 Score: 116.316 bits (290), Expect = 1.109e-25 Identity = 122/452 (26.99%), Postives = 186/452 (41.15%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P + T+LI I F + + I + P P I P N P F PA H S DST+ F P P Y + S++PD+ + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 593 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------IGSETSLI--IHRGGFFS-PWKTPKPIMDRWENQGSPQTSLSAPAI----PQNLP-FPPALHRSSF--PDSTEAFDPRK-------PDPYELYEKSRAIYESRRPDY--------------------KELDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 992 HSP 2 Score: 55.8398 bits (133), Expect = 4.296e-7 Identity = 98/473 (20.72%), Postives = 167/473 (35.31%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH-----------NPNYDMINFYLQKTEG-------------------GFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF----IPDTFYESKKTNTIKYS-----QPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH N N+ + EG GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E + + +S S +++ + + + P + L L RQD + RQ P Y P D Q P P Y +T +Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 763 LDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKR 1213 HSP 3 Score: 52.7582 bits (125), Expect = 3.101e-6 Identity = 27/86 (31.40%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
LKK N GFG T++ D + L+VK++ DGPA + G ++ GD++ N++ ++G +V+K+F+ V +S+ L + +
Sbjct: 425 LSTTLKKSNMGFGFTIIGGDEPD--EFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCR 508
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Human
Match: MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18957]) HSP 1 Score: 115.931 bits (289), Expect = 1.266e-25 Identity = 122/452 (26.99%), Postives = 185/452 (40.93%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P + T+LI I F + + I + P P I P N P F PA H S DST+ F P ++PD P YE + + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 455 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------IGSETSLI--IHRGGFFS-PWKTPKPIMDRWENQGSPQTSLSAPAI----PQNLP-FPPALHRSSF--PDSTEAFDP-------------------------RKPD--PYELYEKSRAIYESRRPDYKELDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 854 HSP 2 Score: 56.225 bits (134), Expect = 3.158e-7 Identity = 98/473 (20.72%), Postives = 167/473 (35.31%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH-----------NPNYDMINFYLQKTEG-------------------GFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF----IPDTFYESKKTNTIKYS-----QPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH N N+ + EG GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E + + +S S +++ + + + P + L L RQD + RQ P Y P D Q P P Y +T +Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 625 LDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKR 1075 HSP 3 Score: 53.1434 bits (126), Expect = 2.382e-6 Identity = 27/86 (31.40%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
LKK N GFG T++ D + L+VK++ DGPA + G ++ GD++ N++ ++G +V+K+F+ V +S+ L + +
Sbjct: 287 LSTTLKKSNMGFGFTIIGGDEPD--EFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCR 370
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Celegans
Match: magi-1 (MAGI (Membrane Associated Guanylate kinase Inverted) homolog [Source:UniProtKB/TrEMBL;Acc:D3YT29]) HSP 1 Score: 157.918 bits (398), Expect = 2.070e-39 Identity = 138/519 (26.59%), Postives = 237/519 (45.66%), Query Frame = 2
Query: 503 AERFDVVLKKGNQGFGLTLV-DDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK-----IIQASRMRSHH----NPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQD----STKLFQPENCKTLR----QIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVE--RDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
E + KG +G G TL+ +D + ++VK++ GPA G+++ GDIL N ++G E +F + E++ + V + I A+R+ + + + D+ + K GFGF + + + ++ K+ L++ D I + + PH Q+V +L++ P + V R + + +F+ Y + N+ + + P PA S +D +T QP IP+S PS+ + + P++IP + Y K P + ++V L R P GFGFRL+GG E + +G I+ G ++ G + GD I++I+ + E +HSE V LL+ AA++ + KL + R SR +P GSL +VLL R+ + FGFV++S+ + +G+I PGS A +C L +GDR++AVNG L + D I +IK S L++ +T+
Sbjct: 221 GELISTKIVKGAKGLGFTLIGNDSSSRGDEFIQVKSVLSGGPAAANGVLRSGDILVRVNGRLLLGATQKEACDVFVAIPVNEAVDIQVCRGYELFIDPANRIVTENVYAAAKSRDLHEIDIFKGSEGFGFTIADNLNGQRIKKILFPSQCPNLME-GDTIVELDGRNVRPIPHTQLVDMLRERPIGYRGKLVVKRGSPKTRSRTPSAAFR----------YGEPQTNM----------MDSAAPLPVRSKTPAERQTSRTEEDQNVRNTLQRQPAVTSEWEGMSSAIPASRMRPSSTTLGFAT--PNYIPLSQYNQK---------PSDLITVSLIRKPV-GFGFRLLGGVESKTPLSVGQIVIGGAAEEDGRLQEGDEIVEIDGHNVEGASHSEAVVLLEAAAQNKHVKL-IVRRPSRTDPAR--RGSLNSAGPSGSYDVLLHRNENDGFGFVLMSSQHKNGST-VGQIQPGSPAARCGRLSVGDRVIAVNGIDILSLSHPDTISLIKDSGLSVRLTI 702
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Celegans
Match: magi-1 (MAGI (Membrane Associated Guanylate kinase Inverted) homolog [Source:UniProtKB/TrEMBL;Acc:D3YT29]) HSP 1 Score: 157.532 bits (397), Expect = 2.344e-39 Identity = 138/519 (26.59%), Postives = 237/519 (45.66%), Query Frame = 2
Query: 503 AERFDVVLKKGNQGFGLTLV-DDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK-----IIQASRMRSHH----NPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQD----STKLFQPENCKTLR----QIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVE--RDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
E + KG +G G TL+ +D + ++VK++ GPA G+++ GDIL N ++G E +F + E++ + V + I A+R+ + + + D+ + K GFGF + + + ++ K+ L++ D I + + PH Q+V +L++ P + V R + + +F+ Y + N+ + + P PA S +D +T QP IP+S PS+ + + P++IP + Y K P + ++V L R P GFGFRL+GG E + +G I+ G ++ G + GD I++I+ + E +HSE V LL+ AA++ + KL + R SR +P GSL +VLL R+ + FGFV++S+ + +G+I PGS A +C L +GDR++AVNG L + D I +IK S L++ +T+
Sbjct: 195 GELISTKIVKGAKGLGFTLIGNDSSSRGDEFIQVKSVLSGGPAAANGVLRSGDILVRVNGRLLLGATQKEACDVFVAIPVNEAVDIQVCRGYELFIDPANRIVTENVYAAAKSRDLHEIDIFKGSEGFGFTIADNLNGQRIKKILFPSQCPNLME-GDTIVELDGRNVRPIPHTQLVDMLRERPIGYRGKLVVKRGSPKTRSRTPSAAFR----------YGEPQTNM----------MDSAAPLPVRSKTPAERQTSRTEEDQNVRNTLQRQPAVTSEWEGMSSAIPASRMRPSSTTLGFAT--PNYIPLSQYNQK---------PSDLITVSLIRKPV-GFGFRLLGGVESKTPLSVGQIVIGGAAEEDGRLQEGDEIVEIDGHNVEGASHSEAVVLLEAAAQNKHVKL-IVRRPSRTDPAR--RGSLNSAGPSGSYDVLLHRNENDGFGFVLMSSQHKNGST-VGQIQPGSPAARCGRLSVGDRVIAVNGIDILSLSHPDTISLIKDSGLSVRLTI 676
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Celegans
Match: magi-1 (MAGI (Membrane Associated Guanylate kinase Inverted) homolog [Source:UniProtKB/TrEMBL;Acc:D3YT29]) HSP 1 Score: 157.147 bits (396), Expect = 2.386e-39 Identity = 135/517 (26.11%), Postives = 235/517 (45.45%), Query Frame = 2
Query: 503 AERFDVVLKKGNQGFGLTLV-DDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK-----IIQASRMRSHH----NPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDST--KLFQPENCKTLRQIPSSYSTPSANLIPDVS----QQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVE--RDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
E + KG +G G TL+ +D + ++VK++ GPA G+++ GDIL N ++G E +F + E++ + V + I A+R+ + + + D+ + K GFGF + + + ++ K+ L++ D I + + PH Q+V +L++ P + V R + + +F+ Y + N+ + + P PA S +D Q + T S + P++ + P + P++IP + Y K P + ++V L R P GFGFRL+GG E + +G I+ G ++ G + GD I++I+ + E +HSE V LL+ AA++ + KL + R SR +P GSL +VLL R+ + FGFV++S+ + +G+I PGS A +C L +GDR++AVNG L + D I +IK S L++ +T+
Sbjct: 168 GELISTKIVKGAKGLGFTLIGNDSSSRGDEFIQVKSVLSGGPAAANGVLRSGDILVRVNGRLLLGATQKEACDVFVAIPVNEAVDIQVCRGYELFIDPANRIVTENVYAAAKSRDLHEIDIFKGSEGFGFTIADNLNGQRIKKILFPSQCPNLME-GDTIVELDGRNVRPIPHTQLVDMLRERPIGYRGKLVVKRGSPKTRSRTPSAAFR----------YGEPQTNM----------MDSAAPLPVRSKTPAERQTSRTEEDQNVRNTLQRQPAVTSEWEGMSSAIPASRMRPSSTTLGFATPNYIPLSQYNQK---------PSDLITVSLIRKPV-GFGFRLLGGVESKTPLSVGQIVIGGAAEEDGRLQEGDEIVEIDGHNVEGASHSEAVVLLEAAAQNKHVKL-IVRRPSRTDPAR--RGSLNSAGPSGSYDVLLHRNENDGFGFVLMSSQHKNGST-VGQIQPGSPAARCGRLSVGDRVIAVNGIDILSLSHPDTISLIKDSGLSVRLTI 649
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Celegans
Match: magi-1 (MAGI (Membrane Associated Guanylate kinase Inverted) homolog [Source:UniProtKB/TrEMBL;Acc:D3YT29]) HSP 1 Score: 157.532 bits (397), Expect = 3.751e-39 Identity = 135/517 (26.11%), Postives = 235/517 (45.45%), Query Frame = 2
Query: 503 AERFDVVLKKGNQGFGLTLV-DDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK-----IIQASRMRSHH----NPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDST--KLFQPENCKTLRQIPSSYSTPSANLIPDVS----QQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVE--RDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
E + KG +G G TL+ +D + ++VK++ GPA G+++ GDIL N ++G E +F + E++ + V + I A+R+ + + + D+ + K GFGF + + + ++ K+ L++ D I + + PH Q+V +L++ P + V R + + +F+ Y + N+ + + P PA S +D Q + T S + P++ + P + P++IP + Y K P + ++V L R P GFGFRL+GG E + +G I+ G ++ G + GD I++I+ + E +HSE V LL+ AA++ + KL + R SR +P GSL +VLL R+ + FGFV++S+ + +G+I PGS A +C L +GDR++AVNG L + D I +IK S L++ +T+
Sbjct: 420 GELISTKIVKGAKGLGFTLIGNDSSSRGDEFIQVKSVLSGGPAAANGVLRSGDILVRVNGRLLLGATQKEACDVFVAIPVNEAVDIQVCRGYELFIDPANRIVTENVYAAAKSRDLHEIDIFKGSEGFGFTIADNLNGQRIKKILFPSQCPNLME-GDTIVELDGRNVRPIPHTQLVDMLRERPIGYRGKLVVKRGSPKTRSRTPSAAFR----------YGEPQTNM----------MDSAAPLPVRSKTPAERQTSRTEEDQNVRNTLQRQPAVTSEWEGMSSAIPASRMRPSSTTLGFATPNYIPLSQYNQK---------PSDLITVSLIRKPV-GFGFRLLGGVESKTPLSVGQIVIGGAAEEDGRLQEGDEIVEIDGHNVEGASHSEAVVLLEAAAQNKHVKL-IVRRPSRTDPAR--RGSLNSAGPSGSYDVLLHRNENDGFGFVLMSSQHKNGST-VGQIQPGSPAARCGRLSVGDRVIAVNGIDILSLSHPDTISLIKDSGLSVRLTI 901
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Celegans
Match: magi-1 (MAGI (Membrane Associated Guanylate kinase Inverted) homolog [Source:UniProtKB/TrEMBL;Acc:D3YT29]) HSP 1 Score: 157.147 bits (396), Expect = 4.705e-39 Identity = 135/517 (26.11%), Postives = 235/517 (45.45%), Query Frame = 2
Query: 503 AERFDVVLKKGNQGFGLTLV-DDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK-----IIQASRMRSHH----NPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDST--KLFQPENCKTLRQIPSSYSTPSANLIPDVS----QQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVE--RDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
E + KG +G G TL+ +D + ++VK++ GPA G+++ GDIL N ++G E +F + E++ + V + I A+R+ + + + D+ + K GFGF + + + ++ K+ L++ D I + + PH Q+V +L++ P + V R + + +F+ Y + N+ + + P PA S +D Q + T S + P++ + P + P++IP + Y K P + ++V L R P GFGFRL+GG E + +G I+ G ++ G + GD I++I+ + E +HSE V LL+ AA++ + KL + R SR +P GSL +VLL R+ + FGFV++S+ + +G+I PGS A +C L +GDR++AVNG L + D I +IK S L++ +T+
Sbjct: 420 GELISTKIVKGAKGLGFTLIGNDSSSRGDEFIQVKSVLSGGPAAANGVLRSGDILVRVNGRLLLGATQKEACDVFVAIPVNEAVDIQVCRGYELFIDPANRIVTENVYAAAKSRDLHEIDIFKGSEGFGFTIADNLNGQRIKKILFPSQCPNLME-GDTIVELDGRNVRPIPHTQLVDMLRERPIGYRGKLVVKRGSPKTRSRTPSAAFR----------YGEPQTNM----------MDSAAPLPVRSKTPAERQTSRTEEDQNVRNTLQRQPAVTSEWEGMSSAIPASRMRPSSTTLGFATPNYIPLSQYNQK---------PSDLITVSLIRKPV-GFGFRLLGGVESKTPLSVGQIVIGGAAEEDGRLQEGDEIVEIDGHNVEGASHSEAVVLLEAAAQNKHVKL-IVRRPSRTDPAR--RGSLNSAGPSGSYDVLLHRNENDGFGFVLMSSQHKNGST-VGQIQPGSPAARCGRLSVGDRVIAVNGIDILSLSHPDTISLIKDSGLSVRLTI 901
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Fly
Match: Magi (gene:FBgn0034590 transcript:FBtr0342874) HSP 1 Score: 130.183 bits (326), Expect = 2.327e-30 Identity = 73/189 (38.62%), Postives = 112/189 (59.26%), Query Frame = 2
Query: 1433 ETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
E V L R GFGFR++GG EEG QV +G I+P G DQ IN GD I+ I+ + +H +VV+L+ E+A G++ + +R+ R S ++ R +V+++R E FGFVI+S+ N IG++ PGS A++C EL +GDRI+AVN G+ + DV+ +IK S L++ +T+
Sbjct: 925 ELTEVTLERQ-ALGFGFRIVGGTEEGSQVTVGHIVPGGAADQDQRINTGDEILSIDGINVLNSSHHKVVSLVGESA--LRGQVTMILRRRRTPLLQQAPVSTQLRRYPYDVIVSRHENEGFGFVIISSSNHYYGSTIGKLIPGSPADRCGELKVGDRIVAVNRIEIAGMSHGDVVNLIKESGLHVRLTI 1110 HSP 2 Score: 52.373 bits (124), Expect = 2.371e-6 Identity = 28/86 (32.56%), Postives = 41/86 (47.67%), Query Frame = 2
Query: 1430 QETVSVQLTRSP---------TKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAA 1660
Q VS QL R P +GFGF ++ + IG +IP P D+CG + GD I+ +N +H +VV L+ E+
Sbjct: 1018 QAPVSTQLRRYPYDVIVSRHENEGFGFVIISSSNHYYGSTIGKLIPGSPADRCGELKVGDRIVAVNRIEIAGMSHGDVVNLIKESG 1103
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Fly
Match: Magi (gene:FBgn0034590 transcript:FBtr0071636) HSP 1 Score: 130.183 bits (326), Expect = 2.327e-30 Identity = 73/189 (38.62%), Postives = 112/189 (59.26%), Query Frame = 2
Query: 1433 ETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
E V L R GFGFR++GG EEG QV +G I+P G DQ IN GD I+ I+ + +H +VV+L+ E+A G++ + +R+ R S ++ R +V+++R E FGFVI+S+ N IG++ PGS A++C EL +GDRI+AVN G+ + DV+ +IK S L++ +T+
Sbjct: 925 ELTEVTLERQ-ALGFGFRIVGGTEEGSQVTVGHIVPGGAADQDQRINTGDEILSIDGINVLNSSHHKVVSLVGESA--LRGQVTMILRRRRTPLLQQAPVSTQLRRYPYDVIVSRHENEGFGFVIISSSNHYYGSTIGKLIPGSPADRCGELKVGDRIVAVNRIEIAGMSHGDVVNLIKESGLHVRLTI 1110 HSP 2 Score: 52.373 bits (124), Expect = 2.371e-6 Identity = 28/86 (32.56%), Postives = 41/86 (47.67%), Query Frame = 2
Query: 1430 QETVSVQLTRSP---------TKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAA 1660
Q VS QL R P +GFGF ++ + IG +IP P D+CG + GD I+ +N +H +VV L+ E+
Sbjct: 1018 QAPVSTQLRRYPYDVIVSRHENEGFGFVIISSSNHYYGSTIGKLIPGSPADRCGELKVGDRIVAVNRIEIAGMSHGDVVNLIKESG 1103
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Fly
Match: Magi (gene:FBgn0034590 transcript:FBtr0342873) HSP 1 Score: 130.183 bits (326), Expect = 2.327e-30 Identity = 73/189 (38.62%), Postives = 112/189 (59.26%), Query Frame = 2
Query: 1433 ETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
E V L R GFGFR++GG EEG QV +G I+P G DQ IN GD I+ I+ + +H +VV+L+ E+A G++ + +R+ R S ++ R +V+++R E FGFVI+S+ N IG++ PGS A++C EL +GDRI+AVN G+ + DV+ +IK S L++ +T+
Sbjct: 925 ELTEVTLERQ-ALGFGFRIVGGTEEGSQVTVGHIVPGGAADQDQRINTGDEILSIDGINVLNSSHHKVVSLVGESA--LRGQVTMILRRRRTPLLQQAPVSTQLRRYPYDVIVSRHENEGFGFVIISSSNHYYGSTIGKLIPGSPADRCGELKVGDRIVAVNRIEIAGMSHGDVVNLIKESGLHVRLTI 1110 HSP 2 Score: 52.373 bits (124), Expect = 2.371e-6 Identity = 28/86 (32.56%), Postives = 41/86 (47.67%), Query Frame = 2
Query: 1430 QETVSVQLTRSP---------TKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAA 1660
Q VS QL R P +GFGF ++ + IG +IP P D+CG + GD I+ +N +H +VV L+ E+
Sbjct: 1018 QAPVSTQLRRYPYDVIVSRHENEGFGFVIISSSNHYYGSTIGKLIPGSPADRCGELKVGDRIVAVNRIEIAGMSHGDVVNLIKESG 1103
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0335521) HSP 1 Score: 72.7886 bits (177), Expect = 1.486e-12 Identity = 52/196 (26.53%), Postives = 88/196 (44.90%), Query Frame = 2
Query: 1475 FGFRLMGGAEEGC--------QVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEP-HSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAV-----NPTEPCGIG----RINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDG 2008
GF ++GG + C ++I I+P G +CG + GD I+ +N K TH + V L + ++ LT+ +H+P G V VLL+++ E G I + NP +P G +IN A + L +G R+L VNG S G ++D + +++++ I++ V G
Sbjct: 1154 LGFSIIGGTDHSCVPFGTREPGIFISHIVPGGIASKCGKLRMGDRILKVNEADVSKATHQDAVLELLKPGD----EIKLTI---QHDPLPPGFQSIEVVYVKTEEVLLSKAEGERLGMHIKGGLNGQRGNPADPSDEGVFVSKINSVGAARRDGRLKVGMRLLEVNGHSLLGASHQDAVNVLRNAGNEIQLVVCKG 1342
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0335522) HSP 1 Score: 71.633 bits (174), Expect = 2.995e-12 Identity = 52/196 (26.53%), Postives = 88/196 (44.90%), Query Frame = 2
Query: 1475 FGFRLMGGAEEGC--------QVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEP-HSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAV-----NPTEPCGIG----RINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDG 2008
GF ++GG + C ++I I+P G +CG + GD I+ +N K TH + V L + ++ LT+ +H+P G V VLL+++ E G I + NP +P G +IN A + L +G R+L VNG S G ++D + +++++ I++ V G
Sbjct: 1154 LGFSIIGGTDHSCVPFGTREPGIFISHIVPGGIASKCGKLRMGDRILKVNEADVSKATHQDAVLELLKPGD----EIKLTI---QHDPLPPGFQSIEVVYVKTEEVLLSKAEGERLGMHIKGGLNGQRGNPADPSDEGVFVSKINSVGAARRDGRLKVGMRLLEVNGHSLLGASHQDAVNVLRNAGNEIQLVVCKG 1342
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Zebrafish
Match: magi2b (membrane associated guanylate kinase, WW and PDZ domain containing 2b [Source:ZFIN;Acc:ZDB-GENE-141211-6]) HSP 1 Score: 119.783 bits (299), Expect = 4.412e-27 Identity = 123/465 (26.45%), Postives = 198/465 (42.58%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNT--PDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK----SRHEPHSGIHGSLKVERDCR-------------NVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEI-TVRDGDINRLKTIKYELPRHSSPELQFTETPETFSDLPTQPVSIM 2128
++++ + K GFGF + + +V +V L + D I I + + H QVV LLK P + R TT S + + S + +S + P G P T +P + L + D L+ E + + + S+QP P T +S ++Y + V V L R T GFGFR++GG E + IGAII N P ++ G + GD ++ ++ + H V+ L+ AA+ NG++ LTVR+ + +P GS R +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRI+AVN S + + D++K+IK + L + + + + D+N + SP + +P+T S TQ M
Sbjct: 475 ELLSLTITKGAEGFGFTIADSPTGQRVKQVLEPQGCPGLCE-GDLIVEINQKCLQGLNHTQVVQLLKDCPVGTEATLVIQRGTTAGGEDFSTWWTGKVMWDPQGSPQTGLSATLLPH--------GAPHPAQTLHRSSVPDSEAFHLGKPDPYDLY--EKSRAIYE----------------SRQP-LPPRTLTDS---TGVEYQE----VEVHLLREKT-GFGFRILGGDEAVQAIVIGAIIENSPAERDGRLRPGDELVSVDRMPVGGRPHRYVIDLMHAAAR--NGQVTLTVRRRVLTQQSQPCEENGGSANQNSSPRGHAVCPVNLPPTTDVVIHRKESEGFGFVIISSLNRPETTNTITVPHKIGRIIEGSPADRCGKLKVGDRIMAVNCQSIINMPHADIVKLIKDAGLTVTLHIIPEEDVNGAHSAPTS--EKQSPMVAQKHSPQTQSSPATQQSPTM 899 HSP 2 Score: 72.0182 bits (175), Expect = 2.923e-12 Identity = 98/451 (21.73%), Postives = 177/451 (39.25%), Query Frame = 2
Query: 506 ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII----------------QASRMRSHH------NPNYDMINFYLQKTEGGFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNES-----FQNMDYSMNSSIYSKISRNI-----------------DPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTL----RQIPSSYSTPSANLIPDVSQQPDFI---PDTFYESKKTNTIKYSQPQET--VSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAK 1663
+ +V L + GFG ++ + ++ + + AI ++ PA + G ++PGD L + +++ + G VI + + LTV + + Q S R H P D++ + +++EG FGF++ + + H++ ++ D LK D+I + I + PH +V L+K LH D + ++E Q SS ++ S + PL +Q PG + T + RQD +P+ C+ RQ P Y P + D Q P P + ++ + Y +PQ+ +V+L +S KGFGF + GG E +++ + +GP + G + GD II+IN ST +H+ + L+ +
Sbjct: 648 QEVEVHLLREKTGFGFRILGG--DEAVQAIVIGAIIENSPAERDGRLRPGDELVSVDRMPVGGRPHRYVIDLMHAAARNGQVTLTVRRRVLTQQSQPCEENGGSANQNSSPRGHAVCPVNLPPTTDVV-IHRKESEG-FGFVIISSLNRPETTNTITVPHKIGRIIEGSPADRCGKLKVGDRIMAVNCQSIINMPHADIVKLIKDAGLTVTLHIIPEEDVNGAHSAPTSEKQSPMVAQKHSPQTQSSPATQQSPTMAHPSPPAPHPSPATTQPSPLLVDQSPGAPHANQAGTGNKKHTQKSEVKARQD----VKPDICQAAYTDYRQPPVDYRHPP---VADYRQPPTMEYRHPPALIDYRQHSIADY-RPQDYDYFTVELEKS-VKGFGFSIRGGREYKMDLFVLRLAEDGPAVRNGRMRVGDQIIEINGESTRDMSHARAIELIKAGGR 1085
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Zebrafish
Match: magi2b (membrane associated guanylate kinase, WW and PDZ domain containing 2b [Source:ZFIN;Acc:ZDB-GENE-141211-6]) HSP 1 Score: 118.627 bits (296), Expect = 1.016e-26 Identity = 125/466 (26.82%), Postives = 200/466 (42.92%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISG---PCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK----SRHEPHSGIHGSLKVERDCR-------------NVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEI-TVRDGDINRLKTIKYELPRHSSPELQFTETPETFSDLPTQPVSIM 2128
++++ + K GFGF + + +V +V L + D I I + + H QVV LLK P + R TT + F + D ++ DP P G+S P P H S+ ++ L +P+ + + Y S+QP P T +S ++Y + V V L R T GFGFR++GG E + IGAII N P ++ G + GD ++ ++ + H V+ L+ AA+ NG++ LTVR+ + +P GS R +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRI+AVN S + + D++K+IK + L + + + + D+N + SP + +P+T S TQ M
Sbjct: 613 ELLSLTITKGAEGFGFTIADSPTGQRVKQVLEPQGCPGLCE-GDLIVEINQKCLQGLNHTQVVQLLKDCPVGTEATLVIQRGTTAGL-------FTSWD----------PAKQWDP---QGSPQTGLSATLLPHGAPHPAQTLHRSSVPDSEAFHLGKPDPYDLYEKSRAIYE----------SRQP-LPPRTLTDS---TGVEYQE----VEVHLLREKT-GFGFRILGGDEAVQAIVIGAIIENSPAERDGRLRPGDELVSVDRMPVGGRPHRYVIDLMHAAAR--NGQVTLTVRRRVLTQQSQPCEENGGSANQNSSPRGHAVCPVNLPPTTDVVIHRKESEGFGFVIISSLNRPETTNTITVPHKIGRIIEGSPADRCGKLKVGDRIMAVNCQSIINMPHADIVKLIKDAGLTVTLHIIPEEDVNGAHSAPTS--EKQSPMVAQKHSPQTQSSPATQQSPTM 1034 HSP 2 Score: 53.1434 bits (126), Expect = 1.567e-6 Identity = 51/206 (24.76%), Postives = 93/206 (45.15%), Query Frame = 2
Query: 1079 SISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQD--STKLFQPENCKTL----RQIPSSYSTPSANLIPDVSQQPDFI---PDTFYESKKTNTIKYSQPQET--VSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAK 1663
S+S ++M S ++ + +DP M GI + + P +P+ +L R + + + +P+ C+ RQ P Y P + D Q P P + ++ + Y +PQ+ +V+L +S KGFGF + GG E +++ + +GP + G + GD II+IN ST +H+ + L+ +
Sbjct: 1075 SVSQAGLESM---QTGSAMTQAAPVLDP----GMTGIQTTIIGSVPVPVPSQLYLHDTRSEVKARQDVKPDICQAAYTDYRQPPVDYRHPP---VADYRQPPTMEYRHPPALIDYRQHSIADY-RPQDYDYFTVELEKS-VKGFGFSIRGGREYKMDLFVLRLAEDGPAVRNGRMRVGDQIIEINGESTRDMSHARAIELIKAGGR 1268 HSP 3 Score: 50.8322 bits (120), Expect = 8.627e-6 Identity = 29/89 (32.58%), Postives = 45/89 (50.56%), Query Frame = 2
Query: 1382 TFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
T Y K T +Q + T + + GFGF ++GG E + + ++IP GP Q ++ GDVI+ IN+ TH++VV L
Sbjct: 407 TIYREKPPFTRDATQLKGTFLTTVLQKSNMGFGFTIIGGDEPDEFLQVKSVIPEGPAAQDSKMDTGDVIVYINDICVLGTTHADVVKLF 495
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Zebrafish
Match: magi2b (membrane associated guanylate kinase, WW and PDZ domain containing 2b [Source:ZFIN;Acc:ZDB-GENE-141211-6]) HSP 1 Score: 118.627 bits (296), Expect = 1.104e-26 Identity = 125/466 (26.82%), Postives = 200/466 (42.92%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISG---PCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK----SRHEPHSGIHGSLKVERDCR-------------NVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEI-TVRDGDINRLKTIKYELPRHSSPELQFTETPETFSDLPTQPVSIM 2128
++++ + K GFGF + + +V +V L + D I I + + H QVV LLK P + R TT + F + D ++ DP P G+S P P H S+ ++ L +P+ + + Y S+QP P T +S ++Y + V V L R T GFGFR++GG E + IGAII N P ++ G + GD ++ ++ + H V+ L+ AA+ NG++ LTVR+ + +P GS R +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRI+AVN S + + D++K+IK + L + + + + D+N + SP + +P+T S TQ M
Sbjct: 613 ELLSLTITKGAEGFGFTIADSPTGQRVKQVLEPQGCPGLCE-GDLIVEINQKCLQGLNHTQVVQLLKDCPVGTEATLVIQRGTTAGL-------FTSWD----------PAKQWDP---QGSPQTGLSATLLPHGAPHPAQTLHRSSVPDSEAFHLGKPDPYDLYEKSRAIYE----------SRQP-LPPRTLTDS---TGVEYQE----VEVHLLREKT-GFGFRILGGDEAVQAIVIGAIIENSPAERDGRLRPGDELVSVDRMPVGGRPHRYVIDLMHAAAR--NGQVTLTVRRRVLTQQSQPCEENGGSANQNSSPRGHAVCPVNLPPTTDVVIHRKESEGFGFVIISSLNRPETTNTITVPHKIGRIIEGSPADRCGKLKVGDRIMAVNCQSIINMPHADIVKLIKDAGLTVTLHIIPEEDVNGAHSAPTS--EKQSPMVAQKHSPQTQSSPATQQSPTM 1034 HSP 2 Score: 52.7582 bits (125), Expect = 2.154e-6 Identity = 51/206 (24.76%), Postives = 93/206 (45.15%), Query Frame = 2
Query: 1079 SISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQD--STKLFQPENCKTL----RQIPSSYSTPSANLIPDVSQQPDFI---PDTFYESKKTNTIKYSQPQET--VSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAK 1663
S+S ++M S ++ + +DP M GI + + P +P+ +L R + + + +P+ C+ RQ P Y P + D Q P P + ++ + Y +PQ+ +V+L +S KGFGF + GG E +++ + +GP + G + GD II+IN ST +H+ + L+ +
Sbjct: 1075 SVSQAGLESM---QTGSAMTQAAPVLDP----GMTGIQTTIIGSVPVPVPSQLYLHDTRSEVKARQDVKPDICQAAYTDYRQPPVDYRHPP---VADYRQPPTMEYRHPPALIDYRQHSIADY-RPQDYDYFTVELEKS-VKGFGFSIRGGREYKMDLFVLRLAEDGPAVRNGRMRVGDQIIEINGESTRDMSHARAIELIKAGGR 1268 HSP 3 Score: 50.8322 bits (120), Expect = 9.351e-6 Identity = 29/89 (32.58%), Postives = 45/89 (50.56%), Query Frame = 2
Query: 1382 TFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
T Y K T +Q + T + + GFGF ++GG E + + ++IP GP Q ++ GDVI+ IN+ TH++VV L
Sbjct: 407 TIYREKPPFTRDATQLKGTFLTTVLQKSNMGFGFTIIGGDEPDEFLQVKSVIPEGPAAQDSKMDTGDVIVYINDICVLGTTHADVVKLF 495
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Zebrafish
Match: wu:fi36a10 (wu:fi36a10 [Source:ZFIN;Acc:ZDB-GENE-030131-6139]) HSP 1 Score: 118.242 bits (295), Expect = 1.166e-26 Identity = 119/431 (27.61%), Postives = 184/431 (42.69%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRD-TTNLIRSI-----SNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQET--VSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKS----RHEPHSGIH-----------GSLK---VERDCR------NVLLTRSPEEEFGFVIVSAVNPTEPC----GIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
++++ L K GGFGF + +C +V + + LLK D I I R + H QVV +LK P ++ V+R T+ ++S+ + Q D SSI + +P P +P F P+ + S P P Y K+ ++ S+P T + V + R+ GFGFR++GG VYIGAI+P G ++ G + GD +I I+ + K+H +V+ L+ AA+ NG++ LTVR+ E G++ GS K VE +V L R E FGFVI+++ N P IGRI GS ++ L +GDRI AVNG S L + D++++IK + + +TV
Sbjct: 573 ELVSVPLVKGPGGFGFAIADCPLGQKVKMILDAQWCRGLLK-GDVIKEINRQNVQTLSHAQVVDILKDLPVGSEVNVLVLRGGQTSPVKSLKPITPAMPITQKQDIITTSSISTDTPSPAEP----------------APQSLP---------------FPPQLIR--------------------SSSPKLDPTELY--LKSKAMQDSKPINTKELDVFIKRNQETGFGFRVLGGEGPDQPVYIGAIVPLGAAEKDGRLRAGDELICIDGVPVKGKSHKQVLELMTNAAR--NGQVMLTVRRKLTFQDREEDDGVYPPAPQALSLVNGSPKPSHVEVSGHSHPQPYDVTLQRKDNEGFGFVILTSKNKPPPGVIPHKIGRIIEGSPTDRSGHLKVGDRISAVNGQSIIDLSHNDIVQLIKEAGNAVTLTV 947 HSP 2 Score: 50.8322 bits (120), Expect = 8.154e-6 Identity = 26/83 (31.33%), Postives = 46/83 (55.42%), Query Frame = 2
Query: 1760 NVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLN--IEITVR 2002
+V + R+ E FGF ++ P +P IG I P AEK L GD ++ ++G +G +K V++++ ++ N + +TVR
Sbjct: 736 DVFIKRNQETGFGFRVLGGEGPDQPVYIGAIVPLGAAEKDGRLRAGDELICIDGVPVKGKSHKQVLELMTNAARNGQVMLTVR 818
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Zebrafish
Match: wu:fi36a10 (wu:fi36a10 [Source:ZFIN;Acc:ZDB-GENE-030131-6139]) HSP 1 Score: 118.242 bits (295), Expect = 1.685e-26 Identity = 121/431 (28.07%), Postives = 186/431 (43.16%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRD-TTNLIRSI-----SNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQET--VSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKS-----RHE--------PH--SGIHGSLK---VERDCR------NVLLTRSPEEEFGFVIVSAVNPTEPC----GIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
++++ L K GGFGF + +C +V + + LLK D I I R + H QVV +LK P ++ V+R T+ ++S+ + Q D SSI + +P P +P F P+ + S P P Y K+ ++ S+P T + V + R+ GFGFR++GG VYIGAI+P G ++ G + GD +I I+ + K+H +V+ L+ AA+ NG++ LTVR+ R E P S ++GS K VE +V L R E FGFVI+++ N P IGRI GS ++ L +GDRI AVNG S L + D++++IK + + +TV
Sbjct: 573 ELVSVPLVKGPGGFGFAIADCPLGQKVKMILDAQWCRGLLK-GDVIKEINRQNVQTLSHAQVVDILKDLPVGSEVNVLVLRGGQTSPVKSLKPITPAMPITQKQDIITTSSISTDTPSPAEP----------------APQSLP---------------FPPQLIR--------------------SSSPKLDPTELY--LKSKAMQDSKPINTKELDVFIKRNQETGFGFRVLGGEGPDQPVYIGAIVPLGAAEKDGRLRAGDELICIDGVPVKGKSHKQVLELMTNAAR--NGQVMLTVRRKLTFQDREEDDGVYPPAPQALSLVNGSPKPSHVEVSGHSHPQPYDVTLQRKDNEGFGFVILTSKNKPPPGVIPHKIGRIIEGSPTDRSGHLKVGDRISAVNGQSIIDLSHNDIVQLIKEAGNAVTLTV 947 HSP 2 Score: 50.8322 bits (120), Expect = 8.050e-6 Identity = 26/83 (31.33%), Postives = 46/83 (55.42%), Query Frame = 2
Query: 1760 NVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLN--IEITVR 2002
+V + R+ E FGF ++ P +P IG I P AEK L GD ++ ++G +G +K V++++ ++ N + +TVR
Sbjct: 736 DVFIKRNQETGFGFRVLGGEGPDQPVYIGAIVPLGAAEKDGRLRAGDELICIDGVPVKGKSHKQVLELMTNAARNGQVMLTVR 818
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Xenopus
Match: gdf5 (growth differentiation factor 5 [Source:Xenbase;Acc:XB-GENE-481784]) HSP 1 Score: 129.798 bits (325), Expect = 5.684e-30 Identity = 155/603 (25.70%), Postives = 246/603 (40.80%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK--------------------IIQASRMRSHHNPNYDMINFYLQKT-------------------------------------EGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPD--FIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEG--CQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------SRHEPHSG--------------------IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
+LKK N GFG T++ D + L+VK++ +GPA + G ++ GD++ N+ ++G +V+K+F+ V +S+ L + + +I+ + + NY+ Y+ +T GFGF + + +V ++ DVQ L D I I + + + H +VV LLK+ P V + T+L+ I F +S S SK R+ P +S P P+ F P H S DST+ F P P Y + YES++ KY+ E + V L R + GFGFR++GG E G + IGA+I G D+ G + GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S HS G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVN S + + D++K+IK + L++ + +
Sbjct: 417 LSTILKKSNMGFGFTIIGGDEPD--EFLQVKSVIPEGPAAQDGKMETGDVIVYINEACVLGYTHADVVKIFQSVPIGQSVNLVLCRGYPLPYDPEDSANNLVSPLAVIERPPVVVNGRNNYETYLEYISRTPLENTFPPPPPTHDDNVSMASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DVQGCPGLFEGDLIVEINQQNVQNLNHLEVVELLKECP---------VGNETSLV--IQRGGF----FSPWKS--SKPVRS---------PQTSLSAPSLPPNVPFAPMLHRSSF--PDSTEAFDPRK-------PDPYELYEKSR-------------AIYESRR----KYNTFSE-LDVHLRRQES-GFGFRILGGDEPGQPVSILIGAVIAMGSADRDGRLRPGDELLYVDGIPVAGKTHRYVIDLMHNAAR--NGQVNLTVRRKVLSIADTCPENGRSPGSASTQHSSPRSDSAYPNSNHSAPCNPSPPEGFTSQSMQSSDVVIHRKENEGFGFVIISSLNRPESGATIAVPHKIGRIIEGSPADRCGKLKVGDRILAVNSQSIINMPHADIVKLIKDAGLSVTLCI 958 HSP 2 Score: 56.6102 bits (135), Expect = 2.277e-7 Identity = 100/468 (21.37%), Postives = 167/468 (35.68%), Query Frame = 2
Query: 494 YHIAERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII-------------QASRMRSHHNPNYDMI----------------NFYLQ-----------KTEGGFGFIL----------GNCKDEHQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYST---PSANLIPDVSQQP--DFI-PDTFYESKKTN--------TIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
Y+ DV L++ GFG ++ + + A+ G A + G ++PGD L + I + G VI + + LTV + + S H +P D F Q K GFGF++ H++ ++ D LK D+I + I + PH +V L+K + L T+ + E + + +S S +++ P+ Q P S P H L P L+ SSY + ++ PD+ Q P D+ P T Y + I + Q + +V+L + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 723 YNTFSELDVHLRRQESGFGFRILGGDEPGQPVSILIGAVIAMGSADRDGRLRPGDELLYVDGIPVAGKTHRYVIDLMHNAARNGQVNLTVRRKVLSIADTCPENGRSPGSASTQHSSPRSDSAYPNSNHSAPCNPSPPEGFTSQSMQSSDVVIHRKENEGFGFVIISSLNRPESGATIAVPHKIGRIIEGSPADRCGKLKVGDRILAVNSQSIINMPHADIVKLIK----DAGLSVTLC--------IVPQEELNSPASAPSSEKQSPMAQQHSPMA-QQSPVAQQS---------PVAHSL------------PPQPLQLQGHESSYRSEVKARQDVKPDIRQPPFTDYRQPSTDYRQPPVDYRHPPVHSLIFHLQDYDYFTVELEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVKLLLKR 1151
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Xenopus
Match: gdf5 (growth differentiation factor 5 [Source:Xenbase;Acc:XB-GENE-481784]) HSP 1 Score: 119.783 bits (299), Expect = 4.353e-27 Identity = 126/454 (27.75%), Postives = 193/454 (42.51%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQ-MPGIGISGPCNTPD--FIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----SRHE-PHSGI--------HGSLKVERDCRN------------------------VLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ DVQ L D I I + + + H +VV LLK+ P V + T+L+ I F + K S+ I + NQ P +S P P+ F P H S DST+ F P PD + +K+ I S + + V L R GFGFR++GG E G + IGA+I G D+ G + GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ R+ P +G H S + + N V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVN S + + D++K+IK + L++ + +
Sbjct: 193 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DVQGCPGLFEGDLIVEINQQNVQNLNHLEVVELLKECP---------VGNETSLV--IQRGGFFSP---------WKSSKPIMERWENQGSPQTSLSAPSLPPNVPFAPMLHRSSF--PDSTEAFDPRK-----------------------------PDPYELYEKSRAIYESPDYKELDVHLRRQ-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLRPGDELLYVDGIPVAGKTHRYVIDLMHNAAR--NGQVNLTVRRKVLSIGRYTCPENGRSPGSASTQHSSPRSDSAYPNSNHSAPCNPSPPEGFTSQSMQSSDVVIHRKENEGFGFVIISSLNRPESGATIAVPHKIGRIIEGSPADRCGKLKVGDRILAVNSQSIINMPHADIVKLIKDAGLSVTLCI 589 HSP 2 Score: 54.6842 bits (130), Expect = 6.605e-7 Identity = 103/491 (20.98%), Postives = 174/491 (35.44%), Query Frame = 2
Query: 506 ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII--------------QASRMRSHHNPNYDMI----------------NFYLQ-----------KTEGGFGFIL----------GNCKDEHQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLI-PDV--SQQPDFI-----PDTFYESKKTNTIKYSQPQ-------ETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLT 1774
+ DV L++ GFG ++ + + + + A+ G A + G ++PGD L + I + G VI + + LTV + + S H +P D F Q K GFGF++ H++ ++ D LK D+I + I + PH +V L+K + L + + + S+E M + P+ ++ P P + RQD + RQ + Y P + P V QQP I P Y +T ++ P + +V+L + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L ++ R H + SL +R+ + L+T
Sbjct: 359 KELDVHLRRQESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLRPGDELLYVDGIPVAGKTHRYVIDLMHNAARNGQVNLTVRRKVLSIGRYTCPENGRSPGSASTQHSSPRSDSAYPNSNHSAPCNPSPPEGFTSQSMQSSDVVIHRKENEGFGFVIISSLNRPESGATIAVPHKIGRIIEGSPADRCGKLKVGDRILAVNSQSIINMPHADIVKLIKDAGLSVTLCIVPQEELNSPASAPSSEKQSPMAQQHSPMAQQSPVAQQSPVAHSLPPQ-----PLQLQGHESSYRSEVKARQDVKPDIRQPPFTDYRQPSTDYRQPPVDYRHPPVVDYQQPPPIDYRQPPLIEYRQHSPDTRQFPLPDYRQFQDYDYFTVELEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVKLLLK--RGTGHVPEYASLLPKRNGTDSLIT 835 HSP 3 Score: 51.9878 bits (123), Expect = 4.614e-6 Identity = 26/86 (30.23%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
+LKK N GFG T++ D + L+VK++ +GPA + G ++ GD++ N+ ++G +V+K+F+ V +S+ L + +
Sbjct: 24 LSTILKKSNMGFGFTIIGGDEPD--EFLQVKSVIPEGPAAQDGKMETGDVIVYINEACVLGYTHADVVKIFQSVPIGQSVNLVLCR 107
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Xenopus
Match: gdf5 (growth differentiation factor 5 [Source:Xenbase;Acc:XB-GENE-481784]) HSP 1 Score: 117.857 bits (294), Expect = 3.147e-26 Identity = 126/454 (27.75%), Postives = 194/454 (42.73%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQ-MPGIGISGPCNTPD--FIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----SRHE-PHSGI--------HGSLKVERDCRN------------------------VLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ DVQ L D I I + + + H +VV LLK+ P V + T+L+ I F + K S+ I + NQ P +S P P+ F P H S DST+ F P P Y + YES++ + + + V L R GFGFR++GG E G + IGA+I G D+ G + GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ R+ P +G H S + + N V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVN S + + D++K+IK + L++ + +
Sbjct: 592 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DVQGCPGLFEGDLIVEINQQNVQNLNHLEVVELLKECP---------VGNETSLV--IQRGGFFSP---------WKSSKPIMERWENQGSPQTSLSAPSLPPNVPFAPMLHRSSF--PDSTEAFDPRK-------PDPYELYEKS-------------RAIYESRRYFYLTTGPDYKELDVHLRRQ-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLRPGDELLYVDGIPVAGKTHRYVIDLMHNAAR--NGQVNLTVRRKVLSIGRYTCPENGRSPGSASTQHSSPRSDSAYPNSNHSAPCNPSPPEGFTSQSMQSSDVVIHRKENEGFGFVIISSLNRPESGATIAVPHKIGRIIEGSPADRCGKLKVGDRILAVNSQSIINMPHADIVKLIKDAGLSVTLCI 997 HSP 2 Score: 53.9138 bits (128), Expect = 1.217e-6 Identity = 100/476 (21.01%), Postives = 167/476 (35.08%), Query Frame = 2
Query: 506 ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII--------------QASRMRSHHNPNYDMI----------------NFYLQ-----------KTEGGFGFIL----------GNCKDEHQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLI-PDV--SQQPDFI-----PDTFYESKKTNTIKYSQPQ-------ETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTV-RKSRHEPHSGI 1726
+ DV L++ GFG ++ + + + + A+ G A + G ++PGD L + I + G VI + + LTV + + S H +P D F Q K GFGF++ H++ ++ D LK D+I + I + PH +V L+K + L + + + S+E M + P+ ++ P P + RQD + RQ + Y P + P V QQP I P Y +T ++ P + +V+L + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L + R + H P G+
Sbjct: 767 KELDVHLRRQESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLRPGDELLYVDGIPVAGKTHRYVIDLMHNAARNGQVNLTVRRKVLSIGRYTCPENGRSPGSASTQHSSPRSDSAYPNSNHSAPCNPSPPEGFTSQSMQSSDVVIHRKENEGFGFVIISSLNRPESGATIAVPHKIGRIIEGSPADRCGKLKVGDRILAVNSQSIINMPHADIVKLIKDAGLSVTLCIVPQEELNSPASAPSSEKQSPMAQQHSPMAQQSPVAQQSPVAHSLPPQ-----PLQLQGHESSYRSEVKARQDVKPDIRQPPFTDYRQPSTDYRQPPVDYRHPPVVDYQQPPPIDYRQPPLIEYRQHSPDTRQFPLPDYRQFQDYDYFTVELEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVKLLLKRGTGHVPEYGM 1230 HSP 3 Score: 51.6026 bits (122), Expect = 6.818e-6 Identity = 26/86 (30.23%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
+LKK N GFG T++ D + L+VK++ +GPA + G ++ GD++ N+ ++G +V+K+F+ V +S+ L + +
Sbjct: 423 LSTILKKSNMGFGFTIIGGDEPD--EFLQVKSVIPEGPAAQDGKMETGDVIVYINEACVLGYTHADVVKIFQSVPIGQSVNLVLCR 506
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Xenopus
Match: gdf5 (growth differentiation factor 5 [Source:Xenbase;Acc:XB-GENE-481784]) HSP 1 Score: 117.472 bits (293), Expect = 3.332e-26 Identity = 126/454 (27.75%), Postives = 194/454 (42.73%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQ-MPGIGISGPCNTPD--FIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----SRHE-PHSGI--------HGSLKVERDCRN------------------------VLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ DVQ L D I I + + + H +VV LLK+ P V + T+L+ I F + K S+ I + NQ P +S P P+ F P H S DST+ F P P Y + YES++ + + + V L R GFGFR++GG E G + IGA+I G D+ G + GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ R+ P +G H S + + N V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVN S + + D++K+IK + L++ + +
Sbjct: 438 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DVQGCPGLFEGDLIVEINQQNVQNLNHLEVVELLKECP---------VGNETSLV--IQRGGFFSP---------WKSSKPIMERWENQGSPQTSLSAPSLPPNVPFAPMLHRSSF--PDSTEAFDPRK-------PDPYELYEKSR-------------AIYESRRYFYLTTGPDYKELDVHLRRQ-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLRPGDELLYVDGIPVAGKTHRYVIDLMHNAAR--NGQVNLTVRRKVLSIGRYTCPENGRSPGSASTQHSSPRSDSAYPNSNHSAPCNPSPPEGFTSQSMQSSDVVIHRKENEGFGFVIISSLNRPESGATIAVPHKIGRIIEGSPADRCGKLKVGDRILAVNSQSIINMPHADIVKLIKDAGLSVTLCI 843 HSP 2 Score: 52.373 bits (124), Expect = 3.857e-6 Identity = 28/86 (32.56%), Postives = 47/86 (54.65%), Query Frame = 2
Query: 1442 SVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
+V+L + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 986 TVELEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVKLLLKR 1066 HSP 3 Score: 51.9878 bits (123), Expect = 5.947e-6 Identity = 26/86 (30.23%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
+LKK N GFG T++ D + L+VK++ +GPA + G ++ GD++ N+ ++G +V+K+F+ V +S+ L + +
Sbjct: 269 LSTILKKSNMGFGFTIIGGDEPD--EFLQVKSVIPEGPAAQDGKMETGDVIVYINEACVLGYTHADVVKIFQSVPIGQSVNLVLCR 352
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Xenopus
Match: gdf5 (growth differentiation factor 5 [Source:Xenbase;Acc:XB-GENE-481784]) HSP 1 Score: 117.472 bits (293), Expect = 4.194e-26 Identity = 126/454 (27.75%), Postives = 195/454 (42.95%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQ-MPGIGISGPCNTPD--FIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----SRHE-PHSGI--------HGSLKVERDCRN------------------------VLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ DVQ L D I I + + + H +VV LLK+ P V + T+L+ I F + K S+ I + NQ P +S P P+ F P H S DST+ F P P Y + YES++ + + + V L R + GFGFR++GG E G + IGA+I G D+ G + GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ R+ P +G H S + + N V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVN S + + D++K+IK + L++ + +
Sbjct: 592 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DVQGCPGLFEGDLIVEINQQNVQNLNHLEVVELLKECP---------VGNETSLV--IQRGGFFSP---------WKSSKPIMERWENQGSPQTSLSAPSLPPNVPFAPMLHRSSF--PDSTEAFDPRK-------PDPYELYEKSR-------------AIYESRRYFYLTTGPDYKELDVHLRRQES-GFGFRILGGDEPGQPILIGAVIAMGSADRDGRLRPGDELLYVDGIPVAGKTHRYVIDLMHNAAR--NGQVNLTVRRKVLSIGRYTCPENGRSPGSASTQHSSPRSDSAYPNSNHSAPCNPSPPEGFTSQSMQSSDVVIHRKENEGFGFVIISSLNRPESGATIAVPHKIGRIIEGSPADRCGKLKVGDRILAVNSQSIINMPHADIVKLIKDAGLSVTLCI 997 HSP 2 Score: 51.9878 bits (123), Expect = 4.704e-6 Identity = 28/86 (32.56%), Postives = 47/86 (54.65%), Query Frame = 2
Query: 1442 SVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
+V+L + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 1140 TVELEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVKLLLKR 1220 HSP 3 Score: 51.6026 bits (122), Expect = 7.374e-6 Identity = 26/86 (30.23%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
+LKK N GFG T++ D + L+VK++ +GPA + G ++ GD++ N+ ++G +V+K+F+ V +S+ L + +
Sbjct: 423 LSTILKKSNMGFGFTIIGGDEPD--EFLQVKSVIPEGPAAQDGKMETGDVIVYINEACVLGYTHADVVKIFQSVPIGQSVNLVLCR 506
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Mouse
Match: Magi2 (membrane associated guanylate kinase, WW and PDZ domain containing 2 [Source:MGI Symbol;Acc:MGI:1354953]) HSP 1 Score: 118.627 bits (296), Expect = 7.438e-27 Identity = 121/452 (26.77%), Postives = 185/452 (40.93%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P V T+LI I F + + + + P P + P N P F PA H S DST+ F P PD + +K+ I S + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 202 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------VGSETSLI--IHRGGFFS-PWKTPKPMMDRWENQGSPQTSLSAPAV----PQNLP-FPPALHRSSF--PDSTEAFDPRK-----------------------------PDPYELYEKSRAIYESPDYKELDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 599 HSP 2 Score: 61.6178 bits (148), Expect = 3.996e-9 Identity = 101/472 (21.40%), Postives = 170/472 (36.02%), Query Frame = 2
Query: 506 ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH-----------NPNYDMINFYLQKTEG-------------------GFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQ-MPGIGISGPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF-----IPDTFYESKKTNTIKYSQPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
+ DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH N N+ + EG GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E + + +S S +++ PL + + P + L L RQD + RQ P Y P D SQ P PDT ++ Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 368 KELDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNSPTSAPSSEKQSPMAQQHSPLAQQSPLAQPSPATPNSPVAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYSQPPPLDYRQHSPDT----RQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKR 813 HSP 3 Score: 53.5286 bits (127), Expect = 1.224e-6 Identity = 27/86 (31.40%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
LKK N GFG T++ D + L+VK++ DGPA + G ++ GD++ N++ ++G +V+K+F+ V +S+ L + +
Sbjct: 34 LSTTLKKSNMGFGFTIIGGDEPD--EFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCR 117 HSP 4 Score: 50.8322 bits (120), Expect = 7.985e-6 Identity = 24/59 (40.68%), Postives = 35/59 (59.32%), Query Frame = 2
Query: 1472 GFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
GFGF ++GG E + + ++IP+GP Q G + GDVI+ IN TH++VV L
Sbjct: 44 GFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLF 102
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Mouse
Match: Magi2 (membrane associated guanylate kinase, WW and PDZ domain containing 2 [Source:MGI Symbol;Acc:MGI:1354953]) HSP 1 Score: 115.546 bits (288), Expect = 1.287e-25 Identity = 121/452 (26.77%), Postives = 186/452 (41.15%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P V T+LI I F + + + + P P + P N P F PA H S DST+ F P P Y + S++PD+ + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 592 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------VGSETSLI--IHRGGFFS-PWKTPKPMMDRWENQGSPQTSLSAPAV----PQNLP-FPPALHRSSF--PDSTEAFDPRK-------PDPYELYEKSRAIYESRRPDY--------------------KELDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 991 HSP 2 Score: 62.003 bits (149), Expect = 3.319e-9 Identity = 104/485 (21.44%), Postives = 174/485 (35.88%), Query Frame = 2
Query: 506 ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH-----------NPNYDMINFYLQKTEG-------------------GFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQ-MPGIGISGPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF-----IPDTFYESKKTNTIKYSQPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSR------HEPHS 1720
+ DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH N N+ + EG GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E + + +S S +++ PL + + P + L L RQD + RQ P Y P D SQ P PDT ++ Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++ EPH+
Sbjct: 760 KELDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNSPTSAPSSEKQSPMAQQHSPLAQQSPLAQPSPATPNSPVAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYSQPPPLDYRQHSPDT----RQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKRGTGQVPEYDEPHA 1218 HSP 3 Score: 53.1434 bits (126), Expect = 1.996e-6 Identity = 27/86 (31.40%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
LKK N GFG T++ D + L+VK++ DGPA + G ++ GD++ N++ ++G +V+K+F+ V +S+ L + +
Sbjct: 424 LSTTLKKSNMGFGFTIIGGDEPD--EFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCR 507 HSP 4 Score: 50.8322 bits (120), Expect = 9.113e-6 Identity = 24/59 (40.68%), Postives = 35/59 (59.32%), Query Frame = 2
Query: 1472 GFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
GFGF ++GG E + + ++IP+GP Q G + GDVI+ IN TH++VV L
Sbjct: 434 GFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLF 492
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Mouse
Match: Magi2 (membrane associated guanylate kinase, WW and PDZ domain containing 2 [Source:MGI Symbol;Acc:MGI:1354953]) HSP 1 Score: 114.775 bits (286), Expect = 1.577e-25 Identity = 119/443 (26.86%), Postives = 183/443 (41.31%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
+++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P V T+LI I F + + + + P P + P N P F PA H S DST+ F P ++PD P YE + + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 438 ELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------VGSETSLI--IHRGGFFS-PWKTPKPMMDRWENQGSPQTSLSAPAV----PQNLP-FPPALHRSSF--PDSTEAFDP-------------------------RKPD--PYELYEKSRAIYESRRPDYKELDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 828 HSP 2 Score: 61.6178 bits (148), Expect = 4.738e-9 Identity = 101/472 (21.40%), Postives = 170/472 (36.02%), Query Frame = 2
Query: 506 ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH-----------NPNYDMINFYLQKTEG-------------------GFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQ-MPGIGISGPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF-----IPDTFYESKKTNTIKYSQPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
+ DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH N N+ + EG GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E + + +S S +++ PL + + P + L L RQD + RQ P Y P D SQ P PDT ++ Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 597 KELDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNSPTSAPSSEKQSPMAQQHSPLAQQSPLAQPSPATPNSPVAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYSQPPPLDYRQHSPDT----RQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKR 1042 HSP 3 Score: 53.5286 bits (127), Expect = 1.309e-6 Identity = 27/86 (31.40%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
LKK N GFG T++ D + L+VK++ DGPA + G ++ GD++ N++ ++G +V+K+F+ V +S+ L + +
Sbjct: 261 LSTTLKKSNMGFGFTIIGGDEPD--EFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCR 344 HSP 4 Score: 50.8322 bits (120), Expect = 7.797e-6 Identity = 24/59 (40.68%), Postives = 35/59 (59.32%), Query Frame = 2
Query: 1472 GFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
GFGF ++GG E + + ++IP+GP Q G + GDVI+ IN TH++VV L
Sbjct: 271 GFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLF 329
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Mouse
Match: Magi2 (membrane associated guanylate kinase, WW and PDZ domain containing 2 [Source:MGI Symbol;Acc:MGI:1354953]) HSP 1 Score: 114.005 bits (284), Expect = 2.592e-25 Identity = 123/453 (27.15%), Postives = 189/453 (41.72%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYST-PSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P V T+LI I F + + + + P P + P N P F PA H S DST+ F P P Y + I + QQ +P ++ Y + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 202 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------VGSETSLI--IHRGGFFS-PWKTPKPMMDRWENQGSPQTSLSAPAV----PQNLP-FPPALHRSSF--PDSTEAFDPRK-------PDPYELYEKSRAIYESRQQ---VPPRTSFRMDSSGPDYKE----LDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 615 HSP 2 Score: 62.003 bits (149), Expect = 3.198e-9 Identity = 106/501 (21.16%), Postives = 180/501 (35.93%), Query Frame = 2
Query: 431 FCTNRHMYSSLNSDPKIKSYLYHIA----ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH-----------NPNYDMINFYLQKTEG-------------------GFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQ-MPGIGISGPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF-----IPDTFYESKKTNTIKYSQPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
+ +R +Y S P S+ + + DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH N N+ + EG GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E + + +S S +++ PL + + P + L L RQD + RQ P Y P D SQ P PDT ++ Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 355 YEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNSPTSAPSSEKQSPMAQQHSPLAQQSPLAQPSPATPNSPVAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYSQPPPLDYRQHSPDT----RQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKR 829 HSP 3 Score: 53.5286 bits (127), Expect = 1.141e-6 Identity = 27/86 (31.40%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
LKK N GFG T++ D + L+VK++ DGPA + G ++ GD++ N++ ++G +V+K+F+ V +S+ L + +
Sbjct: 34 LSTTLKKSNMGFGFTIIGGDEPD--EFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCR 117 HSP 4 Score: 50.8322 bits (120), Expect = 7.895e-6 Identity = 24/59 (40.68%), Postives = 35/59 (59.32%), Query Frame = 2
Query: 1472 GFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
GFGF ++GG E + + ++IP+GP Q G + GDVI+ IN TH++VV L
Sbjct: 44 GFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLF 102
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Mouse
Match: Magi2 (membrane associated guanylate kinase, WW and PDZ domain containing 2 [Source:MGI Symbol;Acc:MGI:1354953]) HSP 1 Score: 113.62 bits (283), Expect = 4.842e-25 Identity = 123/453 (27.15%), Postives = 189/453 (41.72%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYST-PSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P V T+LI I F + + + + P P + P N P F PA H S DST+ F P P Y + I + QQ +P ++ Y + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 592 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------VGSETSLI--IHRGGFFS-PWKTPKPMMDRWENQGSPQTSLSAPAV----PQNLP-FPPALHRSSF--PDSTEAFDPRK-------PDPYELYEKSRAIYESRQQ---VPPRTSFRMDSSGPDYKE----LDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 1005 HSP 2 Score: 62.3882 bits (150), Expect = 2.309e-9 Identity = 109/514 (21.21%), Postives = 184/514 (35.80%), Query Frame = 2
Query: 431 FCTNRHMYSSLNSDPKIKSYLYHIA----ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH-----------NPNYDMINFYLQKTEG-------------------GFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQ-MPGIGISGPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF-----IPDTFYESKKTNTIKYSQPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSR------HEPHS 1720
+ +R +Y S P S+ + + DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH N N+ + EG GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E + + +S S +++ PL + + P + L L RQD + RQ P Y P D SQ P PDT ++ Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++ EPH+
Sbjct: 745 YEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNSPTSAPSSEKQSPMAQQHSPLAQQSPLAQPSPATPNSPVAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYSQPPPLDYRQHSPDT----RQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKRGTGQVPEYDEPHA 1232 HSP 3 Score: 52.7582 bits (125), Expect = 2.122e-6 Identity = 27/86 (31.40%), Postives = 50/86 (58.14%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
LKK N GFG T++ D + L+VK++ DGPA + G ++ GD++ N++ ++G +V+K+F+ V +S+ L + +
Sbjct: 424 LSTTLKKSNMGFGFTIIGGDEPD--EFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCR 507 HSP 4 Score: 50.8322 bits (120), Expect = 9.523e-6 Identity = 24/59 (40.68%), Postives = 35/59 (59.32%), Query Frame = 2
Query: 1472 GFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
GFGF ++GG E + + ++IP+GP Q G + GDVI+ IN TH++VV L
Sbjct: 434 GFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLF 492
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q86UL8|MAGI2_HUMAN (Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 OS=Homo sapiens OX=9606 GN=MAGI2 PE=1 SV=3) HSP 1 Score: 114.39 bits (285), Expect = 1.952e-24 Identity = 124/453 (27.37%), Postives = 189/453 (41.72%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYST-PSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P + T+LI I F + + I + P P I P N P F PA H S DST+ F P P Y + I + QQ +P ++ Y + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 593 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------IGSETSLI--IHRGGFFS-PWKTPKPIMDRWENQGSPQTSLSAPAI----PQNLP-FPPALHRSSF--PDSTEAFDPRK-------PDPYELYEKSRAIYESRQQ---VPPRTSFRMDSSGPDYKE----LDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 1006 HSP 2 Score: 56.225 bits (134), Expect = 1.341e-6 Identity = 103/504 (20.44%), Postives = 178/504 (35.32%), Query Frame = 2
Query: 431 FCTNRHMYSSLNSDPKIKSYLYHIA----ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH-----------NPNYDMINFYLQKTEG-------------------GFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF----IPDTFYESKKTNTIKYS-----QPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
+ +R +Y S P S+ + + DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH N N+ + EG GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E + + +S S +++ + + + P + L L RQD + RQ P Y P D Q P P Y +T +Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 746 YEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKR 1227
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9WVQ1|MAGI2_MOUSE (Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 OS=Mus musculus OX=10090 GN=Magi2 PE=1 SV=2) HSP 1 Score: 113.62 bits (283), Expect = 3.455e-24 Identity = 123/453 (27.15%), Postives = 189/453 (41.72%), Query Frame = 2
Query: 788 MRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYST-PSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
M S +++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P V T+LI I F + + + + P P + P N P F PA H S DST+ F P P Y + I + QQ +P ++ Y + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 592 MASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------VGSETSLI--IHRGGFFS-PWKTPKPMMDRWENQGSPQTSLSAPAV----PQNLP-FPPALHRSSF--PDSTEAFDPRK-------PDPYELYEKSRAIYESRQQ---VPPRTSFRMDSSGPDYKE----LDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 1005 HSP 2 Score: 62.003 bits (149), Expect = 2.560e-8 Identity = 106/501 (21.16%), Postives = 180/501 (35.93%), Query Frame = 2
Query: 431 FCTNRHMYSSLNSDPKIKSYLYHIA----ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH-----------NPNYDMINFYLQKTEG-------------------GFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQ-MPGIGISGPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF-----IPDTFYESKKTNTIKYSQPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
+ +R +Y S P S+ + + DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH N N+ + EG GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E + + +S S +++ PL + + P + L L RQD + RQ P Y P D SQ P PDT ++ Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 745 YEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNSPTSAPSSEKQSPMAQQHSPLAQQSPLAQPSPATPNSPVAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYSQPPPLDYRQHSPDT----RQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKR 1219
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|O88382|MAGI2_RAT (Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 OS=Rattus norvegicus OX=10116 GN=Magi2 PE=1 SV=1) HSP 1 Score: 112.464 bits (280), Expect = 6.358e-24 Identity = 123/447 (27.52%), Postives = 190/447 (42.51%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQ-MPGIGISGPC--NTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYST-PSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------------------------------SRHEPHSG----IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
+++ + K GFGF + + +V ++ D+Q L D I I + + + H +VV +LK P V T+LI I F +S + + R + NQ P +S P + F PA H S DST+ F P P Y + I + QQ +P ++ Y + + V L R GFGFR++GG E G + IGA+I G D+ G ++ GD ++ ++ KTH V+ L+ AA+ NG++NLTVR+ S H S G +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVNG S + + D++K+IK + L++ + +
Sbjct: 602 ELMTLTIVKGAKGFGFTIADSPTGQRVKQIL---DIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCP---------VGSETSLI--IHRGGF----FSPWKTPKPMVDR-----WENQGSPQTSLSAPAVPQSLPFPPALHRSSF--PDSTEAFDPRK-------PDPYELYEKSRAIYESRQQ---VPPRTSFRMDSSGPDYKE----LDVHLRRM-ESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR--NGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYANSNHAAPSNNASPPEGFASHSLQTSDVIIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 1006 HSP 2 Score: 62.3882 bits (150), Expect = 1.762e-8 Identity = 109/502 (21.71%), Postives = 180/502 (35.86%), Query Frame = 2
Query: 431 FCTNRHMYSSLNSDPKIKSYLYHIA----ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHHN-PNYDMINFY---------------------LQ--------KTEGGFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGIS--GPCNTPDFIPATHFLSLH------------RQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF-----IPDTFYESKKTNTIKYSQPQE--TVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
+ +R +Y S P S+ + + DV L++ GFG ++ + + + + A+ G A + G + PGD L + I + G VI + + LTV + + + +HH+ P D + LQ K GFGF++ + + H++ ++ D LK D+I + I + PH +V L+K + L T +R I E N + +S S +++ PL P S P + L L RQD + RQ P Y P D SQ PDT ++ Y QPQ+ +V + + KGFGF + GG E +Y+ + +GP + G + GD II+IN ST TH+ + L+ KS ++ L +++
Sbjct: 746 YEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGG--DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYANSNHAAPSNNASPPEGFASHSLQTSDVIIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIK----DAGLSVT--------LRIIPQEELNNPTSAPSSEKQSPMAQQHSPLAQQHSPLAQPSPATPNSPVAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGG---DYSQPSPLDYRQHSPDT----RQYPLSDYRQPQDFDYFTVDMEKG-AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI----KSGGRRVRLLLKR 1221
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|A1A5G4|MAGI3_XENTR (Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 OS=Xenopus tropicalis OX=8364 GN=magi3 PE=2 SV=1) HSP 1 Score: 110.153 bits (274), Expect = 3.060e-23 Identity = 79/243 (32.51%), Postives = 123/243 (50.62%), Query Frame = 2
Query: 1355 SQQPDFIPDTFYESKKTNTIKYSQPQETVSVQL-TRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKS-------------RHEP--HSG--------IHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPC----GIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
S P P Y KK+ I +P T + + R GFGFR++GG +YIGAIIP G ++ G + D +I I+ + K+H +V+ L+ AA+ NG + LTVR+ +H P H+G + K+ + +V+L R E FGFVI+++ N P IGR+ GS A++C +L +GDRI AVNG S L + +++++IK + + +TV
Sbjct: 698 SCSPKLDPSEVY--KKSKNIFEDKPPNTKDLDVFLRKQESGFGFRVLGGDGPDQAIYIGAIIPLGAAEKDGRLRAADELICIDGVPVKGKSHKQVLDLMTNAAR--NGHVLLTVRRQIYYTDKQQEEEELQHTPPAHNGSPRLNRIEVSAIPKLPAEAYDVILQRKDNEGFGFVILTSKNKPPPGVIPHKIGRVIEGSPADRCRKLKVGDRISAVNGQSIVELSHDNIVQLIKDAGNTVTLTV 936 HSP 2 Score: 55.8398 bits (133), Expect = 1.606e-6 Identity = 35/106 (33.02%), Postives = 57/106 (53.77%), Query Frame = 2
Query: 455 SSLNSDP-KIKSYLYHIAERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
S DP ++K L H + LKK GFG T++ D + L+VK + KDGPA + G I PGD++ N ++G EV++MF+L+ + + +T+ +
Sbjct: 392 SQFTRDPSQLKGALLHTS------LKKSAMGFGFTIIGGDRPD--EFLQVKNVLKDGPAAQDGKIAPGDVIVDINGTCVLGHTHAEVVQMFQLIPINQYVNMTLCR 489
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q4L1J4|MAGI1_RAT (Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Magi1 PE=1 SV=1) HSP 1 Score: 105.916 bits (263), Expect = 6.775e-22 Identity = 164/701 (23.40%), Postives = 276/701 (39.37%), Query Frame = 2
Query: 524 LKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGD-----------------ILSAFNQIDIIGVLPDEVIKMFKL----------------VKEKESIVLT-----------VWKIIQASRMR--------------SHHNPN------------YDMINFYLQKTEGGFGFILGNCKDE--HQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIR-SISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNT----PDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQ----ETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNL------TVRKSRHE-------------PHS---------GIHGSLKVERDCR------------------------NVLLTRSPEEEFGFVIVSAVNPTE-------------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGDINRLKTIKYELPRHSSPELQFTETPETFSDLPTQPVSIMKPISQFDKQIFRTFQQTPDE 2188
L+K ++GFG T+V D + L++K++ DGPA G ++ GD ++ F I I + E+ + + L + +KE I++ K + S M+ SH PN ++I ++ K GFGF + + +V ++ + + L K D I + + + H+QVV +L + P+ + V R + + S ++ + D S NSS +S + + + + P ++ P++ PA + + DS+ +P+ K Q S Y +S P ++ N+ + + Q + + L R T GFGFR++GG E G +YIG I+P G D G + GD +I ++ T K+H VV L+ +AAK + L + TV K+ +E P S G SL +V + R E FGFVIVS+V+ E P IGRI GS A++C +L +GDRILAVNG S + D++ +IK + + + + GD + T+ + ++ + T P T+ + KP SQF+ F+ Q T ++
Sbjct: 474 LRKSSRGFGFTVVGGDEPD--EFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYPLPFDPDDPNTSLVTSVAILDKEPIIVNGQETYDSPASHSSKTGKVSNMKDARPSSPADVASNSSHGYPNDTVSLASSIATQPELITVHIVKGPMGFGFTIADSPGGGGQRVKQIVDSPRCRGL-KEGDLIVEVNKRNVQALTHNQVVDMLIECPKGSEVTLLVQRGGLPVPKKSPKSQPLERKD-SQNSSQHS----------VSSLRSLHTASPSHSAQVLPEYPPA-DVPAPDQTDSSGQKKPDPFKIWAQSRSMYEDRP------MSPSPASGLSKGERDREINSTNFGECQIPDYQEQDIFLWRKET-GFGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDGTPVIGKSHQLVVQLMQQAAKQGHVNLTVRRKVVFTVPKAENEVPSPASSHHSSNQPASLTEEKRTPQGSQNSLNTVSSGSGSTSGIGSGGGGGSGVVSAVLQPYDVEIRRGENEGFGFVIVSSVSRPEAGTTFAGNACVAMPHKIGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDESSNATLLTNAEKIAT--ITTTHAPSQQGTQETRTTTKPKPDSQFE---FKGPQATQEQ 1147 HSP 2 Score: 61.2326 bits (147), Expect = 3.706e-8 Identity = 35/108 (32.41%), Postives = 60/108 (55.56%), Query Frame = 2
Query: 1376 PDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
PD+ +E K + +Q Q+ +V+L R KGFGF L GG E +Y+ + +GP ++CG + GD I++IN +T+ HS + L+ K+ ++ L +R+
Sbjct: 1132 PDSQFEFKGP---QATQEQDFYTVELERG-AKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHSRAIELI----KNGGRRVRLFLRR 1231
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. TrEMBL
Match: A0A077Z874 (Membrane associated guanylate kinase, WW and PDZ OS=Trichuris trichiura OX=36087 GN=TTRE_0000410101 PE=4 SV=1) HSP 1 Score: 174.481 bits (441), Expect = 1.878e-41 Identity = 153/525 (29.14%), Postives = 235/525 (44.76%), Query Frame = 2
Query: 503 AERFDVVLKKGNQGFGLTLV-DDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKIIQASRMRSHHNPNYDMI--NFYLQKTEG--GFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCR----NVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGDINRLKTIKYELPR 2050
E VL KG++G G TLV D + L++K++ GPA K G ++ GD+L N ++G DEVI++F+L+ + + L V + + +P+ D + N YL +G GFGF + + +V KV LL+ D + + + H +V +L+ P V R +++S I+ +D + P+ F SL R + P+ K Q TPS++ S P+++P T Y + + Y + V+V L R PT GFGFRL+GG EEG V +G ++P G Q G + D I++I+ H E V L+ +A++ G++ L VR+ R E I L D R +V + R E FGFVI+S+VN IGRI GS A +C L +GDRILAVNG + + D++ +IK S + +TV D R + + L R
Sbjct: 167 GEMVTAVLVKGHKGLGFTLVGSDGTSRGQEFLQIKSVLPGGPAYKDGRLRMGDVLVFVNDTCVLGYSQDEVIRVFQLISVGQQVTLQVCR--GYPLLFDPCDPSTDFVTQNAYLHIVKGDMGFGFTIADSPYGQKVKKVLDRPRCHGLLE-GDILCQVNGRDVRRLNHAAIVDVLRDCP--------VGRQVAMVVQS-------------------GITSQVD---------------TSRPEHPVGHLFASLPRSKTPGAAPPKPAKPNAQNGGRTRTPSSSYF--ASATPNYVPATVY-----SNLAY----DYVTVNLLRHPT-GFGFRLLGGTEEGSHVRVGQLVPGGAASQDGRLRFNDEIVEIDGQCILNCGHQEAVDLMSDASR--RGRVKLVVRRPRTEFPRSISMPLS-SSDVRAYPFDVTVVRRENEGFGFVIISSVN-RAGSAIGRIINGSPAARCGRLRVGDRILAVNGIGILKMPHGDIVNLIKDSGYAVTLTVGSPDGGRFVFVTFFLLR 630
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. TrEMBL
Match: F1KSV9 (Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Ascaris suum OX=6253 PE=2 SV=1) HSP 1 Score: 171.4 bits (433), Expect = 6.202e-40 Identity = 150/530 (28.30%), Postives = 247/530 (46.60%), Query Frame = 2
Query: 530 KGNQGFGLTLV-DDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVW-----------KII--QASRMRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNG--------TGDVQLLLKT----NDKITNIGRVRIDHF---PHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENC-------KTLRQIPSSYST--PSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIH--GSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
KG +G G TL+ +D + + L++K+I GPA + G++ GD+L N ++G ++F+ + ES+ L V KI+ A RSH D ++K + GFGF + +V K+ GD L ++T G+ + +F PH ++V++L+ P + V R + +F+ + + + S R+ P P S P P P H LSL + + P N T +I ++S PS+ + + P+++P T ++ ETV+V L R P GFGFR++GG EEG + +G I+P G + G + GD II+I+ + ++H+ V L+ ++A ANG + L VR+ + P S L V + +V+LTRS + FGFVI+S+VN IGRI GS A +C +L +GDR++AVNG L + +++ +IK S L++ +T+
Sbjct: 383 KGPKGLGFTLIGNDGSSIHEEFLQIKSIIPGGPAHRDGVLHMGDVLVYVNNECVLGATQSHACRIFQAINIGESVTLQVCRGYPLMLDPTNKIVTENAYAPRSH-----DEKEILIKKGDDGFGFTIFESLQGQRVKKILYPERCENLLEGDTLLEMRTTYPNGSPSKPFGQEVVTNFRGMPHHELVSVLRDCPVGFWAKLIVRRHSPRHRSRTPTAAFRYGE-QRGTPVPSLAPRSKTPAPQPPRPVKTYSSPSTLP---PVPHSLSLENGVAGGYYNPRNTIPRQHERGTHEEIYENFSRVRPSSTSLGFAT--PNYVPMTAL---------FNDGSETVTVNLIRKP-NGFGFRVVGGTEEGTCITVGQIVPGGAAAEDGRMRQGDEIIEIDGKNVVGESHATAVQLMQQSA--ANGHVKLIVRRQKEVPRSTSMPLNQLNVVLNTYDVVLTRSDHDGFGFVIISSVNKNGST-IGRIMEGSPAARCGQLRVGDRVIAVNGIDILSLAHNEIVNLIKDSGLSVRLTI 888
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. TrEMBL
Match: A0A3Q2XBK5 (Membrane associated guanylate kinase, WW and PDZ domain containing 3b OS=Hippocampus comes OX=109280 PE=4 SV=1) HSP 1 Score: 166.392 bits (420), Expect = 2.931e-38 Identity = 150/551 (27.22%), Postives = 250/551 (45.37%), Query Frame = 2
Query: 503 AERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTV---WKIIQASRMRSHHN-----PNY------------DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVR----DTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQ-ETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVR-----KSRH-------EPHSGIHGSLKVER---------DCRNVLLTRSPEEEFGFVIV-SAVNPTE---PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
+ + LKK +QGFG T++ D + L+VK ++ DGPA + GD++ N + ++G EV++MF+ + + + + + + + + + H PN ++++ L K GGFGF + +C +V + D Q L+ D I I R + H QVV +LK FP + V+R ++ +S F ++ +S ++ R + PL Q P ++ P P P TH S + P++++ P Q D +K + + ++P + + V L R GFGFR++GG VYIGAI+PNG ++ G + GD +I I+ + ++H +V+ L+ AA+ NG++ LTVR + RH E + ++GS K+ R + ++ L R E FGFVI+ S P P IGRI GS ++C LH+GDRI AVNG S L + D++++IK + + +TV
Sbjct: 395 GDMYRTALKKSSQGFGFTIIGGDRTD--EFLQVKNVFSDGPAANDNKMASGDVIVEINGLCVLGKTHPEVVQMFQSIPVNQYVDMVLCRGYALPPDVDLDTLHGVVAALPNGRQGESATGMLHPELVSVPLIKGPGGFGFAIADCPLGQKVKMIL---DAQWCRDLQKGDVIKEINRENVQTLSHAQVVDILKDFPVGSEVDVLVLRGGQTSPVKSLKPVSRHVFLPPLWNQHSVLFPTRRRWM-PLAI-QFPRHCLTTPTRAPCAPPTTH-------------------------QSGTPPNSDVSPSSPSQFD---------QKPSCLSSTEPHTKDIDVFLKRDIETGFGFRVLGGEGPQQPVYIGAIVPNGAAEKDGRLRAGDELIGIDGVMVKGRSHKQVLDLMTNAAR--NGQVMLTVRRKVIYRGRHATDEEAQEMPTLVNGSPKLPRLPMPSALDHESFDITLHRKESEGFGFVILTSKSRPPHGVIPHKIGRIIEGSPTDRCGLLHVGDRISAVNGRSILELSHNDIVQLIKEAGNVVTLTV 902
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. TrEMBL
Match: A0A0N4U6S4 (Uncharacterized protein OS=Dracunculus medinensis OX=318479 GN=DME_LOCUS7002 PE=4 SV=1) HSP 1 Score: 162.155 bits (409), Expect = 1.865e-37 Identity = 142/518 (27.41%), Postives = 238/518 (45.95%), Query Frame = 2
Query: 530 KGNQGFGLTLV-DDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKIIQ-------ASRMRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNG--------TGDVQLLLKTN-----DKITNIGRVRIDH--FPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFL---SLHRQDSTKLFQP--ENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
KG +G G TL+ +D + L++K + GPA + G+++PGD+L N ++G ++F+ + E + L V + Q + + + D ++K E GFGF + +V K+ GD L ++T+ T+I ID PH Q+V++L+ P + H V R++ N F+ + ++ + S + R+ P P P +H +L RQ + EN LR PSS S A P+++P N + Y+ ETV+V L R P GFGFR++GG+EEG + IG ++P G G + GD I++I+ + ++H+ V L +AA ANG + L VR+ + S + +V+L R+ + FGFVI+S+ N IG+I GS A +C +L +GDR++AVNG L + +++ +I+ S L++ +T+
Sbjct: 165 KGVKGLGFTLIGNDGSSLYEEFLQIKNVIPGGPAHRDGVLRPGDVLVFVNNECVLGATQSHACRIFQSINVGEMVSLRVCRGYQLFIDPCNKIVLENAYTKFQDEREILIRKGEDGFGFTIFESLQGQRVKKILYPERCENLLEGDTLLQIRTSYPNGSPTSTDIQEQIIDFRGMPHHQLVSILRDCPVGFWAHLLVRRNSPNHRSRTPTAGFRYGE-QRSTPVPSVMPRSRTP----------------APQPTPGSHSNPRNTLPRQYEKHIINDTYENLSHLR--PSSTSLGFAT--------PNYVP--------INPV-YNDSSETVTVNLIRKP-NGFGFRIVGGSEEGTMITIGQVVPGGAAADDGRLRPGDEIVEIDGKNVLGESHNTAVQLTQKAA--ANGHVKLVVRRPKECRRSAFSSDVNTLLTTYDVVLHRNETDGFGFVIISSANRIGST-IGKIIEGSAAARCGQLMIGDRVMAVNGIDIMNLPHNEIVDLIRDSGLSVRLTI 642
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. TrEMBL
Match: A0A3B5MNY1 (Membrane associated guanylate kinase, WW and PDZ domain containing 3b OS=Xiphophorus couchianus OX=32473 PE=4 SV=1) HSP 1 Score: 163.696 bits (413), Expect = 2.266e-37 Identity = 156/552 (28.26%), Postives = 254/552 (46.01%), Query Frame = 2
Query: 431 FCTNRHMYSSLNSDP-KIKSYLYHIAERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKIIQASRMRSHHNP-NYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRD-TTNLIRSISNESFQNMDYSMNSSIYSKISRN-IDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQP--ENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKS---RHEPHSG-----IHGSLKVER---------DCRNVLLTRSPEEEFGFVIVSAVNPTE----PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
FC + +DP ++K +YH A LKK +QGFG T++ D + L+VK + DGPA + GD++ N ++G EV++M++ + + + + + + + H ++++ L K GGFGF + +C +V + D Q L+ D I I R + H QVV +LK FP + V+R T+ ++S+ +S+N + PL Y P IS + F+ T L D+T P N TLR S +P + + + +SK Y++ + V L R GFGFR++GG VYIGAI+P+G ++ G + GD +I I+ + ++H +V+ L+ AA+ NG++ LTVR+ R E ++GS K+ R + ++ L R E FGFVI+++ + P IGRI GS ++C LH+GDRI AVNG S L + D++++IK + + +TV
Sbjct: 391 FCKGSML--GFTADPSQLKGEMYHTA------LKKSSQGFGFTIIGGDRTD--EFLQVKNVLSDGPAALDNKMASGDVIVEINGTCVLGKTHPEVVQMYQSIPINQYVDMVLCRGYPLPPDQPLHGMLQPELVSVPLVKGPGGFGFAIADCPLGQKVKMIL---DAQWCRGLQKGDVIKEINRQNVQSLSHAQVVDILKDFPVGSEVSVLVLRGGQTSPVKSLK-----------------PVSKNALFPLSYPLFPHGDISFNLISKHFVLHTETLDTI-ADATPQALPYHSNTSTLR----SSDSPKRDAT-----------EMYLKSKALLEKPYTK---DIDVFLKRDIETGFGFRVLGGEGPQQPVYIGAIVPSGAAEKDGRLRAGDELIGIDGVMVKGRSHKQVLDLMTNAAR--NGQVMLTVRRKVIYRDEDIQEMTPVLVNGSPKLPRLPMPSALDHESFDITLHRKENEGFGFVILTSKSKPPYGVIPHKIGRIIEGSPTDRCGLLHVGDRISAVNGRSIIELSHNDIVQLIKEAGTVVTLTV 891
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Cavefish
Match: wu:fi36a10 (wu:fi36a10 [Source:ZFIN;Acc:ZDB-GENE-030131-6139]) HSP 1 Score: 153.295 bits (386), Expect = 1.405e-37 Identity = 145/548 (26.46%), Postives = 238/548 (43.43%), Query Frame = 2
Query: 518 VVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK-----------------IIQASRMR--SHHNPNY------DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRD-TTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQET--VSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKS-------------RHEPHSGIHGSLK---------VERDCRNVLLTRSPEEEFGFVIVSAVNPTEPC----GIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
L+K QGFG T++ D + L+VK + +DGPA + I GD++ N ++G +V++MF+ + + + + + + +Q +++ P ++++ L K GGFGF + +C +V + + LLK D I I R + H QVV +LK P ++ V+R T+ ++S+ PC I H +S + S QPE IP S P N++ S P P Y K+ I S+P T + V + R+ GFGFR++GG VYIGAI+P G ++ G + GD ++ I+ + K+H +V+ L+ AA+ NG++ LTVR+ H + ++GS K + + ++ L R E FGFVI+++ N P IGRI GS ++C +L +GDRI AVNG S L + D++++IK + + +TV
Sbjct: 412 TALRKSPQGFGFTIIGGDRPD--EFLQVKNVLRDGPAAQDNKISSGDVIVDINGTCVLGKTHADVVQMFQSISINQYVDMVLCRGYPLPEDAGTSDDGTGDAVQPPQLQDVQPRAPELSTLLQPELVSVPLVKGPGGFGFAIADCPLGQKVKMILDAQWCRGLLK-GDVIKEINRQNVQTLSHAQVVDILKDLPVGAEVNVLVLRGGQTSPVKSLK--------------------------------------PCAAAMPITQKHEISTNTVSSESPSQPE------PIPQSLPFP-PNMV--RSSSPKLDPSELY--LKSKAILDSKPSNTKELDVFIKRNQESGFGFRVLGGEGPDQPVYIGAIVPLGAAEKDGRLRAGDELLCIDGIPVKGKSHKQVLELMTNAAR--NGQVMLTVRRKLTYTDGKEEDSGPAHIAPAQVNGSPKPPHIEVPSPSQPEPYDITLQRKDNEGFGFVILTSKNKPPPGVIPHKIGRIIEGSPTDRCGKLKVGDRISAVNGQSIVDLSHNDIVQLIKQAGNTVTLTV 905 HSP 2 Score: 62.7734 bits (151), Expect = 1.632e-9 Identity = 79/320 (24.69%), Postives = 125/320 (39.06%), Query Frame = 2
Query: 1421 SQPQETVSVQLTRSPTKGFGFRLMGGAEE---GCQVY-IGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIH-------------GSLKVERDCRNVLLTRS-------------PEEEFGFVIVSAVNPTEPC----------GIG----------------RINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGDINRLKTIKYELPRHSSPELQFTETPE-----TFSDLPTQPVSIMKPISQFDKQIFRT-FQQTPDEVL 2194
SQP E + L R +GFGF ++ + G + IG II P D+CG + GD I +N S +H+++V L+ +A + L + + P SG G RD RN L T P+ E G +I S P + C G G R+ A K +H+GD+I+ +NG T+G+ + I++I+ + + +R G + ++P H+ E+ T P + D P+ P S+ P + F T + PDE L
Sbjct: 816 SQP-EPYDITLQRKDNEGFGFVILTSKNKPPPGVIPHKIGRIIEGSPTDRCGKLKVGDRISAVNGQSIVDLSHNDIVQLIKQAGNTVT--LTVLPEEEHSGPPSGTSSAKQSPASQHKAVGQQAASRDDRNGLETEERKEGVAWTEYKSLPKSEMGTMITSG--PKQGCFLVELERGARGFGFSLRGGKEYNMGLFILRLAEDGPALKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGTKVLLLLRPG--------QGQIPDHNVKEMTTTGPPANILRYSAPDEPSMPASLSSPSLSPSEGTFSTSWISVPDEHL 1122 HSP 3 Score: 55.8398 bits (133), Expect = 2.228e-7 Identity = 62/240 (25.83%), Postives = 105/240 (43.75%), Query Frame = 2
Query: 1394 SKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTL-------------------LDEAAKSANGKLNLTVRKSRH---EPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIG-RINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV---RDGDINRLKTIK 2035
S K T SQ Q + R +GFGF ++GG + + ++ +GP Q I+ GDVI+DIN T KTH++VV + L E A +++ V+ + +P + +L ++ + +V L + P FGF I C +G ++ A+ C L GD I +N + + L + V+ I+K + E+ V R G + +K++K
Sbjct: 394 SGKGFTRDPSQLQGAILRTALRKSPQGFGFTIIGGDRPDEFLQVKNVLRDGPAAQDNKISSGDVIVDINGTCVLGKTHADVVQMFQSISINQYVDMVLCRGYPLPEDAGTSDDGTGDAVQPPQLQDVQPRAPELSTL-LQPELVSVPLVKGP-GGFGFAIAD-------CPLGQKVKMILDAQWCRGLLKGDVIKEINRQNVQTLSHAQVVDILKDLPVGAEVNVLVLRGGQTSPVKSLK 624
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Cavefish
Match: magi3b (membrane associated guanylate kinase, WW and PDZ domain containing 3b [Source:ZFIN;Acc:ZDB-GENE-060503-301]) HSP 1 Score: 148.288 bits (373), Expect = 5.115e-36 Identity = 158/598 (26.42%), Postives = 262/598 (43.81%), Query Frame = 2
Query: 470 DP-KIKSYLYHIAERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKL--------------------VKEKESIVLTVWKIIQAS----RMRSHHNPNY--DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQ-ETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKS---RHEPHSG--------------IHGSLK---------VERDCRNVLLTRSPEEEFGFVIVSAVNPTEPC----GIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV--RDGDIN-RLKTIKYELPRHSSPELQFTE 2080
DP ++K LYH A L+K +QGFG T++ D + L+VK + DGPA + GD++ N ++G +V++MF+ V+E V+T +I + +H ++++ L K GGFGF + +C +V + + LLK D I I R + H QVV +LK+ P ++ V+R R ES ++ ++ SS P +M ST L + C + P + + S+ L P S + D + + +K T+ + PQ + + V + R GFGFR++GG VYIGAIIP G ++ G + GD ++ I+ + + K+H +V+ L+ AA+ NG++ L+VR+ R E ++GS + ++ + ++ L R E FGFVI+++ + P IGRI GS ++C L +GDRI AVNG S L + D++++IK + + +TV DG+ N ++ ++ EL L TE
Sbjct: 341 DPTQLKGDLYHTA------LRKSSQGFGFTIIGGDRPD--EFLQVKNVLADGPAAHDNKMSSGDVIVEINGALVLGKTHADVVQMFQCIPINQYVDMVLCRGYSLPPDVEEDMGEVVTAVPLINGQPLLVKGETHEGAMLQPELVSVPLVKGPGGFGFAIADCPLGQKVKMILDAQWCRGLLK-GDVIKEINRQNVQTLSHAQVVDILKELPVGSEVNLLVLRGGE---RETKRESLGHLVMTVFSS---------SPFQRQEM---------------------------STSLEALDRCHDV-GAPQALTYYSSTL-PCSSPRRDT---SLHRTKPKATVDTTLPQYKELDVFIKRDQETGFGFRVLGGEGPEQPVYIGAIIPQGAAEKDGRLWAGDELMGIDGITVKGKSHKQVLDLMTNAAR--NGQVLLSVRRKVIYRGEFRDNDDEDDGVQSVAPVLVNGSPRPPRIQVPSVLDHESFDITLHRKDSEGFGFVILTSKSKPPPGVIPHKIGRIIEGSPTDRCGLLSVGDRISAVNGQSIIELSHNDIVQLIKDAGHTVTLTVVPEDGEYNLDMEEMRDELAWAEYKTLPITE 883 HSP 2 Score: 62.7734 bits (151), Expect = 1.526e-9 Identity = 57/235 (24.26%), Postives = 106/235 (45.11%), Query Frame = 2
Query: 1433 ETVSVQLTRSPTKGFGFRLMGGAEE---GCQVY-IGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSA-------NGKLNLTVRKSRHEPHSGIHGSLKV-----------ERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGD---INRLKTIKYELPRHSSP 2062
E+ + L R ++GFGF ++ + G + IG II P D+CGL++ GD I +N S + +H+++V L+ +A + +G+ NL + + R E + +L + ++ C V L R FGF + I R+ A + +GD+I+ +NG T+G+ + I++I+ + + +R G + +++ E P S P
Sbjct: 767 ESFDITLHRKDSEGFGFVILTSKSKPPPGVIPHKIGRIIEGSPTDRCGLLSVGDRISAVNGQSIIELSHNDIVQLIKDAGHTVTLTVVPEDGEYNLDMEEMRDELAWAEYKTLPITEKGTLCVTGSKQGCILVELERG-SRGFGFSLRGGTEYNMGLYILRLAEDGPALLDGRIQVGDQIVEINGEPTQGISHTRAIELIQAGGNKVLLLLRPGQGLVSDNSESVYPEFPTASEP 1000
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Cavefish
Match: magi2a (membrane associated guanylate kinase, WW and PDZ domain containing 2a [Source:ZFIN;Acc:ZDB-GENE-050810-4]) HSP 1 Score: 116.316 bits (290), Expect = 3.978e-26 Identity = 77/248 (31.05%), Postives = 122/248 (49.19%), Query Frame = 2
Query: 1376 PDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHE-----PHSGIH-GSLKVERD---------------------------CRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
PD + K+ + S+ + V V L R GFGFR++GG E G + IGAII N P D+ G + GD ++ ++ K H V+ L+ AA+ NG++ +T+R+ P +G GS+ + +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRILAVN S + + D++K+IK + L++ + +
Sbjct: 558 PDPYDLYAKSRAMYESRQFQEVEVNLRRE-KSGFGFRILGGEEAGQPILIGAIIENSPADKDGRLRPGDELLSVDGIPVAGKPHRYVIDLMHGAAR--NGQVKMTIRRRAQNTGDQCPQNGRSPGSISTQHSSPRSDLNSGTFSNNSAPTEMAANQSLQASDVIIQRKESEGFGFVIISSLNRPETAAAAAVPHKIGRIIEGSPADRCGKLKVGDRILAVNNQSIVSMAHADIVKLIKDAGLSVTLRI 802 HSP 2 Score: 54.6842 bits (130), Expect = 4.072e-7 Identity = 39/133 (29.32%), Postives = 65/133 (48.87%), Query Frame = 2
Query: 1301 RQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
RQ+P+ P + +PD QQ DF D F +V+L +S KGFGF + GG E +++ + +GP + G + GD II+IN +T + TH+ + L+ KS ++ L +++
Sbjct: 904 RQLPTD---PRSFALPDYRQQQDF--DFF------------------TVELDKS-VKGFGFSIRGGREYKMDLFVLRLAEDGPAIRNGRMRVGDQIIEINGETTREMTHARAIELI----KSGGRRVRLLLKR 1008
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Cavefish
Match: magi2b (membrane associated guanylate kinase, WW and PDZ domain containing 2b [Source:ZFIN;Acc:ZDB-GENE-141211-6]) HSP 1 Score: 110.538 bits (275), Expect = 2.666e-24 Identity = 70/209 (33.49%), Postives = 109/209 (52.15%), Query Frame = 2
Query: 1433 ETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCR-------------NVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
+ V V L R T GFGFR++GG E + IGAII N P ++ G + GD ++ ++ + H V+ L+ AA+ NG++ LTVR+ P + R +V++ R E FGFVI+S++N E P IGRI GS A++C +L +GDRI+AVN S + + D++K+IK + L + + +
Sbjct: 777 QEVEVHLLREKT-GFGFRILGGDEAVQAIVIGAIIENSPAERDGRLRPGDELVSVDRMPVAGRPHRYVIDLMHAAAR--NGQVTLTVRRRVLPPQPKNGAATNQSSSPRGHAVCPVNLPPTTDVVIHRKETEGFGFVIISSLNRPENTTTISVPHKIGRIIEGSPADRCGKLKVGDRIMAVNSQSIINMPHADIVKLIKDAGLTVTLHI 982 HSP 2 Score: 70.0922 bits (170), Expect = 8.311e-12 Identity = 95/425 (22.35%), Postives = 173/425 (40.71%), Query Frame = 2
Query: 506 ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKII------------QASRMRSHH------NPNYDMINFYLQKTEGGFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNS-SIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKT----LRQIPSSYSTPSANLIPDVSQQP--DFIPDTFYESKKTNTIKYSQPQET--VSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAK 1663
+ +V L + GFG ++ + ++ + + AI ++ PA + G ++PGD L + +++ + G VI + + LTV + + Q+S R H P D++ + ++TEG FGF++ + + H++ ++ D LK D+I + I + PH +V L+K LH D + + ++E + +S S + P + P P T RQD +P+ C+ RQ P Y P + D Q P D+ + ++I +PQ+ +V+L +S KGFGF + GG E +++ + +GP + G + GD II+IN ST +H+ + L+ +
Sbjct: 777 QEVEVHLLREKTGFGFRILGG--DEAVQAIVIGAIIENSPAERDGRLRPGDELVSVDRMPVAGRPHRYVIDLMHAAARNGQVTLTVRRRVLPPQPKNGAATNQSSSPRGHAVCPVNLPPTTDVV-IHRKETEG-FGFVIISSLNRPENTTTISVPHKIGRIIEGSPADRCGKLKVGDRIMAVNSQSIINMPHADIVKLIKDAGLTVTLHIIPEEDVSGPHSAPTSEKQSPLVGQKHSPQTQSSPAAQQSPTVVHPSPPAPHPSPATTQPSPQLVESEVKARQD----VKPDICQPPYTDYRQPPVDYRHPP---VADYRQPPTMDYRHPPPLIDYRQHSIPDYRPQDYDYFTVELEKS-VKGFGFSIRGGREYKMDLFVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMSHARAIELIKAGGR 1189 HSP 3 Score: 51.9878 bits (123), Expect = 2.855e-6 Identity = 33/90 (36.67%), Postives = 49/90 (54.44%), Query Frame = 2
Query: 1382 TFYESKKTNTIKYSQPQET-VSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
T Y K T +Q + T +S L +S + GFGF ++GG E + + ++IP GP Q G + GDVI+ IN+ TH++VV L
Sbjct: 407 TIYREKPPFTRDATQLKGTFLSTALQKS-SMGFGFTIIGGDEPDEFLQVKSVIPEGPAAQDGKMATGDVIVYINDICVLGTTHADVVKLF 495
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Cavefish
Match: magi1a (membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1-like [Source:NCBI gene;Acc:103040795]) HSP 1 Score: 99.7525 bits (247), Expect = 6.568e-21 Identity = 107/451 (23.73%), Postives = 178/451 (39.47%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL-------LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNES--FQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEE--------FGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGDINRLKTIKYELPRHSSPELQFTETPETFSDLPTQP 2116
++I +++K + GFGF + +C G Q++ LK D + + + + H+QVV LL K PR + V R + + + S + D S SS +S S + P + + + T +P+ K Q S Y + +PD +Q D F K T GFGFR++GG E G +YIG I+ G D+ G + GD +I ++ T+ K+H VV L+ +AAK G +NLTVR+ S L + T +P+ FGF + + R+ A + ++ +GD IL +NG ST+ + + I++IK+ + ++ GD + +Y+ P P P+ S++ T P
Sbjct: 597 ELITVHMEKGDKGFGFTIADCGS----GTCGGQKVKQIVDYPRCRGLKEGDILVEVNKRNVQSMSHNQVVDLLSKCPRGSEVTMLVQRGKNRPLPAAAPRSCPLERKD-SQGSSQHSVCSHRS---THTDSPARAVP--------PLPSLPPLEPPANGTLQKKPDPFKIWAQSRSMYES----RMPDSQEQ-----DIFLWRKDT----------------------GFGFRILGGNEPGEPIYIGHIVKYGAADEDGRLRSGDELICVDGTAVVGKSHQLVVQLMQQAAK--QGHVNLTVRRKTGYGESSNASLLTNAEKIATITTTHTPQSSSEPRDSKGFGFSLRGGKEYNMDLYVLRLAEDGAAVRNGKMRVGDEILEINGESTKNMKHSRAIELIKNGGRRARLVLKRGDGS---VPEYDGPNDGYPA---PPGPQNLSEMRTMP 992
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003180.1 (pep scaffold:Pmarinus_7.0:GL477326:20216:45383:1 gene:ENSPMAG00000002903.1 transcript:ENSPMAT00000003180.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 83.1889 bits (204), Expect = 1.298e-16 Identity = 68/301 (22.59%), Postives = 128/301 (42.52%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNL-IRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGI---GISGPCNTPDFI--PATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK 1699
++++ + K GFGF + + ++ ++ + L L+ D I I + H VVTLLK+ + R +L S ++++ D ++R+ P ++Q P + GI+ P P + PA F RQ+++++++ P + YE + + + +++ L R GFGFR++GG E G + IGAI+P G D G + GD ++ ++ K+H V+ L+ +AA+ NG + LT+ +
Sbjct: 230 ELVSVKIVKGRAGFGFTIADSPSGQRIKQILDS-RRGLELREGDLILEINGRSVRECSHMDVVTLLKECATGAQASMLLQRGEVDLPAASQMQQAYERHDSQ------GSLTRDSPPRRFSQPPALPPAGIAPPHAQPSYRRPPAEEFRG--RQEASRVYED-------------------------------PQSLYEDSQRVCARAGNSYQEITIHLRRQ-EAGFGFRILGGEELGQPIRIGAIVPGGSADLDGRMRSGDELVSVDGIPVSGKSHRSVIGLMQQAAR--NGLVALTIHR 487 HSP 2 Score: 48.1358 bits (113), Expect = 9.371e-6 Identity = 35/115 (30.43%), Postives = 51/115 (44.35%), Query Frame = 2
Query: 1304 QIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
++PS ST IP V+ P T + N SQ E +L R T GFGF + GG E ++I + GP + + GD I++IN ST H+ + L+
Sbjct: 667 RLPSITSTSVLTFIPSVA---SLDPSTLF----NNLYLCSQDGEYFVAELERGNT-GFGFSIRGGKEYSMDLFILRVAEEGPAIRQSRMRVGDQIMEINGESTRDMMHARAIELI 773
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001444.1 (pep scaffold:Pmarinus_7.0:GL476357:122445:266872:1 gene:ENSPMAG00000001288.1 transcript:ENSPMAT00000001444.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 80.1073 bits (196), Expect = 1.341e-15 Identity = 76/246 (30.89%), Postives = 111/246 (45.12%), Query Frame = 2
Query: 1433 ETVSVQLTRSPTKGFGFRLMGGAEE----GCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTST-EKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHE-PHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVN--PTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGDINRLK-----TIKY--ELPRHSSPELQFTETPETFSDLPTQPVSI 2125
E+V++ L GFG L GG G + IG I P+ P ++CGL+ GD I+ +N T E + +EV L E A + L + + P SG +V L + E G I S + P+EP I I GSVA + L GDR+LA+N + E + + I++ SD +++ VR + N + I Y EL RH P L T + +D PT P+ I
Sbjct: 338 ESVALHLASDGGPGFGLHLQGGTFSTDVFGAPLLIGYIEPDSPAERCGLLQPGDRILSVNGIPTAELGSLAEVSQYLHEQALVGSASLEVEFDVAESVIPSSGTF----------HVTLPKKKGVELGITITSPTHRKPSEPLVITEIKKGSVAHRLGTLEPGDRLLAINHTRLETSSVDETVHILQQSDDFVKLKVRKDEDNSDEQEASGAISYSVELRRHGGP-LGIT---ISGTDEPTDPILI 569 HSP 2 Score: 53.5286 bits (127), Expect = 2.051e-7 Identity = 44/177 (24.86%), Postives = 77/177 (43.50%), Query Frame = 2
Query: 1475 FGFRLMGGAEEGCQ----VYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCG------IGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHS 1975
FGF + GG + + + + + GP D+ G + GD ++ + + + E +L ++ + A + V S E G L VE + ++ G + E CG I +I P S+AE+C LH+GDRIL+V+GS E + ++ ++ S
Sbjct: 23 FGFVVRGGVQSDKKKSRPIVVSHVRQGGPADRDGTLKAGDRLLAVEGIPVQGLSLCEASVVLKQSGQDARVLVEYDV--SVMESVQNATGPLLVE-------IRKTSGANLGISL-----SKESCGMKQIVVIDKIRPASIAERCGALHVGDRILSVDGSGVEQMSVEEASVLLACS 185 HSP 3 Score: 51.2174 bits (121), Expect = 1.034e-6 Identity = 49/188 (26.06%), Postives = 84/188 (44.68%), Query Frame = 2
Query: 1556 QCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSR-----HEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGDINRLKTIKYELPRHSSPELQFTETPETFSDL 2104
+ G + GD ++ IN+T E + E V +L ++ + + L VRK E I S+++ R + +T S +E PT+P I + P +AE+ +H+GD+ILA++G S +G + I +++ R G+I LK K + S F + P T D+
Sbjct: 483 RLGTLEPGDRLLAINHTRLETSSVDETVHILQQS----DDFVKLKVRKDEDNSDEQEASGAISYSVELRRHGGPLGITISGTDE----------PTDPILIASLTPDGLAERTGAIHVGDQILAIDGMSLKGKPLSEAIALLQ----------RAGEIVALKIKKRTAGQPQSANSAF-KAPGTLGDV 645
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010851.1 (pep scaffold:Pmarinus_7.0:GL477227:46102:76179:-1 gene:ENSPMAG00000009830.1 transcript:ENSPMAT00000010851.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 63.5438 bits (153), Expect = 1.580e-10 Identity = 47/180 (26.11%), Postives = 88/180 (48.89%), Query Frame = 2
Query: 1475 FGFRLMGGAEEGCQ----VYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGI-GRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
FGF + GGA E + + + P GP D+ G + GD +++++ S +H+E + +L E + A ++ V S + + G L VE + ++P G + S + +P I +I P SVAE+C LH GD+IL+++G+ E + +++ + N+ + +
Sbjct: 19 FGFVIRGGAHEQRHKSRPILVTCVRPGGPADREGTLKAGDRLLNVDGMSLHGVSHAEALAILRECGQEATLQIEYDV--SIMDSVTNASGPLLVE-------VAKTPGSSLGVSLSSPGHLHKPTIIIDKIRPASVAERCGALHAGDQILSIDGTGMEHCSLLEATQLLASATDNVRLEI 189 HSP 2 Score: 55.4546 bits (132), Expect = 5.793e-8 Identity = 55/193 (28.50%), Postives = 82/193 (42.49%), Query Frame = 2
Query: 1556 QCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHE---PHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAV--NPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGDINR-----LKTIKY--ELPRHSSP-ELQFTETPETF 2095
+CG++ GD ++ + TE+ T EV LL EAA A G+ L V E P SG +V L + E G I S +P I + GSVA + L GD++LA++G + +D I++ D + + +R D N I Y EL R+ P + + T E F
Sbjct: 362 RCGVLQMGDRLLAVGGVPTEEATLDEVHQLLREAA--AGGRTRLQVEFDVAESVVPSSGTF----------HVKLPKRRGVELGITISSPAYRKAGDPLVISDVKKGSVAHRTGTLEPGDQLLAIDGVRLDHCSMEDAAHILRQGDELVRLKIRKDDDNSDELEGTGAISYTVELKRYGGPLGITISGTEEPF 542
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: lin7a (lin-7 homolog A (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-040426-1665]) HSP 1 Score: 57.3806 bits (137), Expect = 1.144e-9 Identity = 30/76 (39.47%), Postives = 42/76 (55.26%), Query Frame = 2
Query: 1469 KGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVR 1696
+G GF +MGG E+ +YI IIP G D+ G + GD ++ +N S E + H + V LL K A G + L VR
Sbjct: 88 EGLGFNIMGGKEQNSPIYISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHEKAVELL----KQAQGTVKLVVR 159 HSP 2 Score: 53.5286 bits (127), Expect = 2.552e-8 Identity = 26/73 (35.62%), Postives = 43/73 (58.90%), Query Frame = 2
Query: 1784 EEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVR 2002
+E GF I+ P I RI PG VA++ L GD++L+VNG S EG H++ ++++K + +++ VR
Sbjct: 87 DEGLGFNIMGGKEQNSPIYISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHEKAVELLKQAQGTVKLVVR 159
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: LIN7B (lin-7 homolog B, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17788]) HSP 1 Score: 56.6102 bits (135), Expect = 1.857e-9 Identity = 30/76 (39.47%), Postives = 41/76 (53.95%), Query Frame = 2
Query: 1469 KGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVR 1696
+G GF +MGG E+ +YI IIP G D+ G + GD ++ +N S E + H V LL K A G + L VR
Sbjct: 78 EGLGFNVMGGKEQNSPIYISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHERAVELL----KQAQGSVKLVVR 149 HSP 2 Score: 52.373 bits (124), Expect = 4.687e-8 Identity = 25/73 (34.25%), Postives = 44/73 (60.27%), Query Frame = 2
Query: 1784 EEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVR 2002
+E GF ++ P I RI PG VA++ L GD++L+VNG S EG H++ ++++K + ++++ VR
Sbjct: 77 DEGLGFNVMGGKEQNSPIYISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHERAVELLKQAQGSVKLVVR 149
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO42539 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S157]) HSP 1 Score: 108.227 bits (269), Expect = 5.617e-24 Identity = 71/232 (30.60%), Postives = 112/232 (48.28%), Query Frame = 2
Query: 1472 GFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPH----SGIH---------------------------------------GSLKVER-------------DCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
GFGFR++GG E+ QV IG I+ P G + GD I+ ++ S H +V++L+ AA+ NG++ L VR+ + P SG+ GS + R D R++ L R E FGFVI+S+V+ + IGRI GS A++C EL++GD+++AVNG+S G+H+ D++ IK S L++ + +
Sbjct: 693 GFGFRIVGGKEDNTQVAIGTIVDGTPAAADGRLRRGDEILYVDGVSVIDGYHRDVISLMKSAAQ--NGQVTLGVRRRQTMPGRSTPSGVRRTSQSNSVRLTSRSAGNLTELARRDEYEPNGFRSPSERAGSTRDRRRSESDKLQPDIPMDYRDITLNRGAHEGFGFVILSSVHKSGST-IGRIIQGSPADRCRELYVGDKLVAVNGTSIVGMHHSDIVNTIKQSGLSVTLRI 921 HSP 2 Score: 54.299 bits (129), Expect = 2.347e-7 Identity = 23/60 (38.33%), Postives = 37/60 (61.67%), Query Frame = 2
Query: 1469 KGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
+GFGF ++GG + G + I +I+P+G + G + GD +I +N S KTH EVV++
Sbjct: 352 RGFGFTIIGGDQSGELLQIKSIVPDGAAAKDGKLRTGDALIKVNGRSVVNKTHQEVVSMF 411 HSP 3 Score: 49.2914 bits (116), Expect = 7.325e-6 Identity = 26/98 (26.53%), Postives = 49/98 (50.00%), Query Frame = 2
Query: 1370 FIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAK 1663
F P ES+ + + + + ++L R +G+GF + GG E +Y+ I G D G I GD +++IN ST+ H++ ++++ +K
Sbjct: 1027 FKPRPKSESELMRDPRTGEVTQVLEIELIRK-NQGYGFSIRGGQEMDMPIYVLKIAEGGVADLDGRIKVGDEVLEINGRSTQHMLHTDAISMIRGGSK 1123
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO46059 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR65]) HSP 1 Score: 59.3066 bits (142), Expect = 6.623e-10 Identity = 49/199 (24.62%), Postives = 87/199 (43.72%), Query Frame = 2
Query: 1433 ETVSVQLTRSPTKGFGFRLMGG-----AEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCG-----IGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
ET+ + L R + G GF + GG ++ +YI +IP G Q G + D I+ +N T+T H + V +A K+A ++ L K R + R ++ + GF I G I +I G A++ L +GD+I++VN + E + ++D ++++K + + I V
Sbjct: 3 ETLEITLERGGS-GLGFSIAGGTDNPHVDDDFGIYITKVIPGGAAAQDGRLQVNDCILSVNGTNTVDIEHQQAV----DALKAAGSQVTLVREKKRGNAPT------------REEIVLIKGSKGLGFSIAGGSGNQHVPGDNGIYITKIIEGGAAQQDGRLQVGDKIISVNLQNLEDVSHEDAVQVLKATKERVTIVV 184
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO34828 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNC4]) HSP 1 Score: 56.225 bits (134), Expect = 2.594e-9 Identity = 35/114 (30.70%), Postives = 59/114 (51.75%), Query Frame = 2
Query: 1403 TNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSR---HEPHSGIHGS 1735
T YS ++ V L + P +G G L GG E G +YI ++P G CG + DVI+ +N S ++ T+ E +++L ++ ++ L V++SR + P+ G GS
Sbjct: 30 TQYTDYSAEEQPFEVHLIKGP-QGLGMSLTGG-ESGGPIYIKRLVPGGSAALCGQLQVNDVILQVNGKSLDRLTYREALSIL----RNCPPEVRLLVKRSRGSSYPPYPGYRGS 137
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO47722 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLN6]) HSP 1 Score: 56.225 bits (134), Expect = 6.207e-9 Identity = 27/66 (40.91%), Postives = 38/66 (57.58%), Query Frame = 2
Query: 1469 KGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKS 1666
+G GF +MGG E+ +YI IIP G D+ G + GD ++ +N S E + H + V LL EA S
Sbjct: 100 EGLGFNVMGGREQNSPIYISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGENHEKAVDLLKEAQGS 165 HSP 2 Score: 47.7506 bits (112), Expect = 4.861e-6 Identity = 23/73 (31.51%), Postives = 42/73 (57.53%), Query Frame = 2
Query: 1784 EEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVR 2002
+E GF ++ P I RI PG VA++ L GD++L+VNG S EG +++ + ++K + ++ + V+
Sbjct: 99 DEGLGFNVMGGREQNSPIYISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGENHEKAVDLLKEAQGSVRLVVK 171
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO45624 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSE9]) HSP 1 Score: 54.6842 bits (130), Expect = 4.486e-8 Identity = 44/169 (26.04%), Postives = 82/169 (48.52%), Query Frame = 2
Query: 1469 KGFGFRLMGGAEEGC-QVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKH 1972
+G G ++GG + +YI I P P ++CG + GD ++ +N+ TH+ + +L K+ + LTV + + +P + D V L + + G + V T + + P VA K + GDR+L+VNG ST+GL +++V+ ++++
Sbjct: 7 QGIGLMVIGGLDTPLGMLYIKDIQPGTPAEKCGHLRTGDQLLQVNDECLVGVTHAYALEVL----KNTPPLVKLTVARKK-DPDR--------DSDVFTVELKKDSKGSLGIHVSGGVG-TNCIDVRHVVPLGVAAKDGRIRKGDRVLSVNGRSTKGLTHQEVLNLLQN 161
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Medaka
Match: wu:fi36a10 (membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 [Source:NCBI gene;Acc:101159504]) HSP 1 Score: 118.242 bits (295), Expect = 1.277e-26 Identity = 120/436 (27.52%), Postives = 188/436 (43.12%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRD-TTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQ---IPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQET--VSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHG-------------------------SLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPC----GIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGDIN 2017
++++ L K GGFGF + +C +V + + LLK D I I R + H QVV +LK + V+R T+ ++S+ + + +S + Q P P +P H S H + + +TL Q P+S S L S P PD ++ I S+P T + V + R+ GFGFR++GG VYIGAI+P G ++ G + GD ++ I+ + K+H +V+ L+ AA+ NG + LTVR R H+ + G L + +V L R E FGFVI+++ N P IGRI GS ++ ++ +GDRI AVNG S L + D++++IK + + +TV D N
Sbjct: 593 ELVSVPLVKGPGGFGFAIADCPLGQKVKMILDAQWCRGLLK-GDVIKEINRQNVQTLSHSQVVDILKDLAVGSEVSVLVLRGGQTSPVKSLK-------------PVTAPVSHTVSQPVLEQ-------APLPVPQQLP--HPPSHHHLQQQQQEMISSTETLTQSDVTPNSLPVSSGTL---RSSSPK--PDASELYLRSKAILDSKPPNTKELDVFIKRNQESGFGFRVLGGEGPDQPVYIGAIVPYGAAEKDGRLRAGDELLCIDGIPVKGKSHKQVLELMTNAAR--NGHVMLTVR--RRLAHADVAGEEANGPQSQQVSSSPKMPRVEAPNSGLPTRPESFDVTLHRRDNEGFGFVILTSKNKPPPGVIPHKIGRIIEGSPTDRLGQMKVGDRISAVNGLSIMELSHNDIVQLIKDAGNTVTLTVVPEDDN 996 HSP 2 Score: 51.9878 bits (123), Expect = 3.102e-6 Identity = 29/84 (34.52%), Postives = 48/84 (57.14%), Query Frame = 2
Query: 1445 VQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVR 1696
V+L RS +GFGF L GG E +YI + +GP + G I+ GD I++IN T+ TH+ + L+ ++ +++L +R
Sbjct: 1056 VELERS-QRGFGFSLRGGKEYNMGLYILRLAEDGPALKDGRIHVGDKIVEINGEPTQGITHTRAIELI----QAGGNRVHLLLR 1134
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Medaka
Match: magi3b (membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 [Source:NCBI gene;Acc:101160155]) HSP 1 Score: 117.857 bits (294), Expect = 1.917e-26 Identity = 118/430 (27.44%), Postives = 189/430 (43.95%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRD-TTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQ-ETVSVQLTRSPTKGFGFRLMGGAEEGCQ-------VYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------SRHEPHSGIHGSLKVER---------DCRNVLLTRSPEEEFGFVIVSAVNPTE----PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
++++ L K GGFGF + +C +V + D Q L+ D I I R + H QVV +LK FP ++ V+R T+ ++S+ + Q + SM + + G+ + P L+ H N TLR S P Y K ++ QP + + V L R GFGFR++GG EG Q VYIGAI+PNG ++ G + GD +I I+ + ++H +V+ L+ AA+ NG++ L+VR+ + ++GS ++ R + ++ L R E FGFVI+++ + P IGRI GS ++C LH+GDRI AVNG S L + D++++IK + + +TV
Sbjct: 584 ELVSVPLVKGPGGFGFAIADCPLGQKVKMIL---DAQWCRGLQKGDVIKEIDRQNVQTLSHAQVVDILKDFPVGSEVNVLVLRGGQTSPVKSL--KPRQELTASMET-----------------LDGVTDATP----------QALTYH----------SNTSTLRS----------------SDSPKREATEMYLKSKA-LLESRQPHTKDIDVFLKRDIETGFGFRVLGG--EGPQQPNVFPQVYIGAIVPNGAAEKDGRLRAGDELIGIDGVMVKGRSHKQVLDLMTNAAR--NGQVMLSVRRKVMYRDVADDEGQEMAPVLVNGSPRLPRIPMPSALDHESFDITLHRKDAEGFGFVILTSKSKPPHGVIPHKIGRIIEGSPTDRCGLLHVGDRISAVNGRSIIELSHNDIVQLIKDAGNVVTLTV 950 HSP 2 Score: 55.0694 bits (131), Expect = 3.450e-7 Identity = 32/92 (34.78%), Postives = 52/92 (56.52%), Query Frame = 2
Query: 461 LNSDP-KIKSYLYHIAERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLV 733
+DP ++K LYH + LKK +QGFG T++ D + L+VK + DGPA + + GD++ N++ ++G EV+KMF+ V
Sbjct: 393 FTADPSQLKGELYHTS------LKKSSQGFGFTIIGGDRTD--EFLQVKNVLSDGPAAQDNKMASGDVIVEINRMCVLGRTHPEVVKMFQSV 476
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Medaka
Match: magi3b (membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 [Source:NCBI gene;Acc:101160155]) HSP 1 Score: 117.472 bits (293), Expect = 2.354e-26 Identity = 118/430 (27.44%), Postives = 189/430 (43.95%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLL--LKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRD-TTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQ-ETVSVQLTRSPTKGFGFRLMGGAEEGCQ-------VYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRK-----------SRHEPHSGIHGSLKVER---------DCRNVLLTRSPEEEFGFVIVSAVNPTE----PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
++++ L K GGFGF + +C +V + D Q L+ D I I R + H QVV +LK FP ++ V+R T+ ++S+ + Q + SM + + G+ + P L+ H N TLR S P Y K ++ QP + + V L R GFGFR++GG EG Q VYIGAI+PNG ++ G + GD +I I+ + ++H +V+ L+ AA+ NG++ L+VR+ + ++GS ++ R + ++ L R E FGFVI+++ + P IGRI GS ++C LH+GDRI AVNG S L + D++++IK + + +TV
Sbjct: 584 ELVSVPLVKGPGGFGFAIADCPLGQKVKMIL---DAQWCRGLQKGDVIKEIDRQNVQTLSHAQVVDILKDFPVGSEVNVLVLRGGQTSPVKSL--KPRQELTASMET-----------------LDGVTDATP----------QALTYH----------SNTSTLRS----------------SDSPKREATEMYLKSKA-LLESRQPHTKDIDVFLKRDIETGFGFRVLGG--EGPQQPNVFPQVYIGAIVPNGAAEKDGRLRAGDELIGIDGVMVKGRSHKQVLDLMTNAAR--NGQVMLSVRRKVMYRDVADDEGQEMAPVLVNGSPRLPRIPMPSALDHESFDITLHRKDAEGFGFVILTSKSKPPHGVIPHKIGRIIEGSPTDRCGLLHVGDRISAVNGRSIIELSHNDIVQLIKDAGNVVTLTV 950 HSP 2 Score: 55.0694 bits (131), Expect = 3.974e-7 Identity = 32/92 (34.78%), Postives = 52/92 (56.52%), Query Frame = 2
Query: 461 LNSDP-KIKSYLYHIAERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLV 733
+DP ++K LYH + LKK +QGFG T++ D + L+VK + DGPA + + GD++ N++ ++G EV+KMF+ V
Sbjct: 393 FTADPSQLKGELYHTS------LKKSSQGFGFTIIGGDRTD--EFLQVKNVLSDGPAAQDNKMASGDVIVEINRMCVLGRTHPEVVKMFQSV 476 HSP 3 Score: 50.8322 bits (120), Expect = 7.349e-6 Identity = 26/73 (35.62%), Postives = 39/73 (53.42%), Query Frame = 2
Query: 1430 QETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
Q ++V+L R P +GFGF L GG E +YI + +GP G I+ GD I++IN H+ + L+
Sbjct: 1022 QGCLTVELERGP-RGFGFSLRGGTEYNMGLYILRLAEDGPAQMDGRIHVGDEIVEINGEPARGIYHTRAIDLI 1093
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Medaka
Match: magi2b (membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 [Source:NCBI gene;Acc:101173221]) HSP 1 Score: 116.316 bits (290), Expect = 6.009e-26 Identity = 119/452 (26.33%), Postives = 188/452 (41.59%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGD-VQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDF-IPDTFYESKKTNTIKYSQ-PQ-ETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDC----------------------------------------------RNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
+++ + K GFGF + + +V +V G L D I + + + H +VV LLK+ P V + T LI+ + S ++ + DP + P +SGP P T F + QP++ + +PD ++ D PD + +K+ I S+ P+ E V V L R T GFGFR++GG E + IGAII N P ++ G + GD +I ++ K H V+ L+ AA+ NG+++LTVR+ P + HG C +V++ R E FGFVI+S++N E P IGRI GS A++C L +G+RILAVNG S + + D++K+IK + L + + +
Sbjct: 622 ELLTVTMVKGAEGFGFTIADSPTGQRVKQVLEPGSQAASGLIEGDLILEVNQQPVAAAGHGRVVELLKECP--------VGAEATLLIQRVGTGHISPWKAS------KQLPDHWDP---HGSPQANLSGPV----LPPGTPFPN----------QPQHRTS---------------VPDSTEGFDLNKPDPYDLYEKSRAIYESRRPEYEEVEVHLLREKT-GFGFRILGGDEAVQAIVIGAIIENTPAERDGRLQPGDELISVDKNVVAGKPHKYVIDLMHAAAR--NGQVSLTVRRRVQMPAASPHGIFSAGEPCPVNGRSPGSVSTQHSSPRSDAASAAGPNAASVPVTAVAPEGSALQTSDVVIHRKENEGFGFVIISSLNRPENPTVITVPHKIGRIIEGSPADRCGRLKVGNRILAVNGQSIINMPHADIVKLIKDAGLTVTLHI 1024 HSP 2 Score: 53.1434 bits (126), Expect = 1.594e-6 Identity = 27/86 (31.40%), Postives = 48/86 (55.81%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
L+K N GFG T++ D + L+VK++ DGPA + G + GD++ N I ++G +V+K+F+ V +S+ L + +
Sbjct: 433 LSTALQKSNMGFGFTIIGGDEPD--EFLQVKSVIPDGPAAQDGKMDTGDVIVYINDICVLGTTHADVVKLFQSVPIGQSVTLVLCR 516 HSP 3 Score: 52.373 bits (124), Expect = 2.628e-6 Identity = 26/74 (35.14%), Postives = 42/74 (56.76%), Query Frame = 2
Query: 1442 SVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAK 1663
+V+L +S TKGFGF + GG E +++ + +GP + G + GD II+IN ST TH+ + L+ +
Sbjct: 1212 TVELEKS-TKGFGFSIRGGREYSMDLFVLRLAEDGPAIRNGRMRVGDQIIEINGDSTRDMTHARAIELIKAGGR 1284 HSP 4 Score: 51.6026 bits (122), Expect = 4.016e-6 Identity = 33/90 (36.67%), Postives = 50/90 (55.56%), Query Frame = 2
Query: 1382 TFYESKKTNTIKYSQPQET-VSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
T Y K T +Q + T +S L +S GFGF ++GG E + + ++IP+GP Q G ++ GDVI+ IN+ TH++VV L
Sbjct: 413 TIYREKPLFTRDPTQLKGTFLSTALQKS-NMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMDTGDVIVYINDICVLGTTHADVVKLF 501
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Medaka
Match: magi2b (membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 [Source:NCBI gene;Acc:101173221]) HSP 1 Score: 113.235 bits (282), Expect = 3.769e-25 Identity = 136/488 (27.87%), Postives = 208/488 (42.62%), Query Frame = 2
Query: 815 DMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSL--HRQ---DSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKK---TNTIKYSQPQ-ETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPH-------------SGIHGSLKVER-----------------------DCRNVLLTRSPEEEFGFVIVSAVNPTE-------PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGDINRLKTIKYELP--RHSSPELQFTETPETFSDLPTQP 2116
+++ + K GFGF + + +V K G+ L++ D I + + + H +VV LLK+ P V + T LI+ + S ++ + DP + P +SGP P T F + HR DST+ F P Y D+ ++ I YES+K T + S P+ E V V L R T GFGFR++GG E + IGAII N P ++ G + GD +I ++ K H V+ L+ AA+ NG+++LTVR+ P S H S + + +V++ R E FGFVI+S++N E P IGRI GS A++C L +G+RILAVNG S + + D++K+IK + L + + + I T + P SP +Q +P+T L QP
Sbjct: 455 ELLTVTMVKGAEGFGFTIADSPTGQRV-KQPGSQAASGLIE-GDLILEVNQQPVAAAGHGRVVELLKECP--------VGAEATLLIQRVGTGHISPWKAS------KQLPDHWDP---HGSPQANLSGPV----LPPGTPFPNQPQHRTSVPDSTEGFD-------LNKPDPY---------DLYEKSRAI----YESRKCVFTARLSGSGPEYEEVEVHLLREKT-GFGFRILGGDEAVQAIVIGAIIENTPAERDGRLQPGDELISVDKNVVAGKPHKYVIDLMHAAAR--NGQVSLTVRRRVQMPGEPCPVNGRSPGSVSTQHSSPRSDAASAAGPNAASVPVTAVAPEGSALQTSDVVIHRKENEGFGFVIISSLNRPENPTVITVPHKIGRIIEGSPADRCGRLKVGNRILAVNGQSIINMPHADIVKLIKDAGLTVTLHI----IPEEGTCSHSGPSSEKQSPMIQ-KHSPQTQPSLVAQP 891 HSP 2 Score: 60.4622 bits (145), Expect = 7.315e-9 Identity = 103/476 (21.64%), Postives = 162/476 (34.03%), Query Frame = 2
Query: 506 ERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKIIQ-------------ASRMRSHHNPNYDMINFYL--------------------------QKTEGGFGFILGNCKDE----------HQVAKV--NGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGP----------------CNTPDFIPATHFLSLH---RQDSTKLFQPENCKTLRQIPSSYSTPSA---------------NLI-----PDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAK 1663
E +V L + GFG ++ + ++ + + AI ++ PA + G +QPGD L + ++ + G VI + + LTV + +Q S H +P D + +K GFGF++ + + H++ ++ D LK ++I + I + PH +V L+K LH T S S + K S P Q PG G + P T P H L RQD F RQ P Y P L+ P +Q P IP F Q + +V+L +S TKGFGF + GG E +++ + +GP + G + GD II+IN ST TH+ + L+ +
Sbjct: 627 EEVEVHLLREKTGFGFRILGG--DEAVQAIVIGAIIENTPAERDGRLQPGDELISVDKNVVAGKPHKYVIDLMHAAARNGQVSLTVRRRVQMPGEPCPVNGRSPGSVSTQHSSPRSDAASAAGPNAASVPVTAVAPEGSALQTSDVVIHRKENEGFGFVIISSLNRPENPTVITVPHKIGRIIEGSPADRCGRLKVGNRILAVNGQSIINMPHADIVKLIKDAGLTVTLHIIPEEGTC---------SHSGPSSEKQSPMIQKHSPQTQPSLVAQ-PGQGGTHPGQVVLQPSQTAAQPGQLQTHTQSPVFHLLRSEVKARQDVKPDFHHPPFTDYRQPPVDYRHPPVTDYRQPPTLDYRHPPGLLDFRQHPAAAQFPLGIPSDFR----------LQDYDYFTVELEKS-TKGFGFSIRGGREYSMDLFVLRLAEDGPAIRNGRMRVGDQIIEINGDSTRDMTHARAIELIKAGGR 1079 HSP 3 Score: 53.1434 bits (126), Expect = 1.285e-6 Identity = 27/86 (31.40%), Postives = 48/86 (55.81%), Query Frame = 2
Query: 512 FDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWK 769
L+K N GFG T++ D + L+VK++ DGPA + G + GD++ N I ++G +V+K+F+ V +S+ L + +
Sbjct: 266 LSTALQKSNMGFGFTIIGGDEPD--EFLQVKSVIPDGPAAQDGKMDTGDVIVYINDICVLGTTHADVVKLFQSVPIGQSVTLVLCR 349 HSP 4 Score: 52.373 bits (124), Expect = 2.556e-6 Identity = 33/90 (36.67%), Postives = 50/90 (55.56%), Query Frame = 2
Query: 1382 TFYESKKTNTIKYSQPQET-VSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLL 1648
T Y K T +Q + T +S L +S GFGF ++GG E + + ++IP+GP Q G ++ GDVI+ IN+ TH++VV L
Sbjct: 246 TIYREKPLFTRDPTQLKGTFLSTALQKS-NMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMDTGDVIVYINDICVLGTTHADVVKLF 334
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000026494.1 (SMESG000026494.1) HSP 1 Score: 1253.81 bits (3243), Expect = 0.000e+0 Identity = 611/616 (99.19%), Postives = 612/616 (99.35%), Query Frame = 2
Query: 449 MYSSLNSDPKIKSYLYHIAERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKIIQASRMRSHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPATHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGDINRLKTIKYELPRHSSPELQFTETPETFSDLPTQPVSIMKPISQFDKQIFRTFQQTPDEVLDESDKPIQGSYIQSIKSGDYQSSNDLLSSLAQKR 2296
MYSSLNSDPKIKSYLYHIAERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKIIQASRMR HHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIP THFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYS P ETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKV+RDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGDINRLKTIKYELPRHSSPELQFTETPETFSDLPTQPVSIMKPISQFDKQIFRTFQQTPDEVLDESDKPIQGSYIQSIKSGDYQSSNDLLSSLAQKR
Sbjct: 1 MYSSLNSDPKIKSYLYHIAERFDVVLKKGNQGFGLTLVDDLFIDNIKLLKVKAIYKDGPAGKCGIIQPGDILSAFNQIDIIGVLPDEVIKMFKLVKEKESIVLTVWKIIQASRMRPHHNPNYDMINFYLQKTEGGFGFILGNCKDEHQVAKVNGTGDVQLLLKTNDKITNIGRVRIDHFPHDQVVTLLKKFPRNHFLHFTVVRDTTNLIRSISNESFQNMDYSMNSSIYSKISRNIDPLFYNQMPGIGISGPCNTPDFIPTTHFLSLHRQDSTKLFQPENCKTLRQIPSSYSTPSANLIPDVSQQPDFIPDTFYESKKTNTIKYSHPPETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVDRDCRNVLLTRSPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVRDGDINRLKTIKYELPRHSSPELQFTETPETFSDLPTQPVSIMKPISQFDKQIFRTFQQTPDEVLDESDKPIQGSYIQSIKSGDYQSSNDLLSSLAQKR 616
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000030959.1 (SMESG000030959.1) HSP 1 Score: 103.99 bits (258), Expect = 2.703e-22 Identity = 61/179 (34.08%), Postives = 104/179 (58.10%), Query Frame = 2
Query: 1472 GFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPT-EPCG--IGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
GFGFR++GGAE+ ++ IG ++P+G + G+I GD ++ +N H +VV L++ AA+ G + L +R+S S + ++ D V L RS E FGFVIV+++ + G IG++ S A+KC L +GDRIL+VNG+S + ++ +++ IK+ N+ + +
Sbjct: 1065 GFGFRIIGGAEDNTKITIGPLVPDGAAIRSGMIKEGDELVSVNGAGVVGALHKKVVQLVEAAARL--GSVTLGLRRSS---KSNLTPQRRIPFD---VTLARSENEGFGFVIVTSMTRSGSHVGEYIGKLIENSPAQKCGLLRVGDRILSVNGNSVSRMRHEKIVQTIKNCGRNVTLRI 1235 HSP 2 Score: 71.2478 bits (173), Expect = 2.747e-12 Identity = 55/211 (26.07%), Postives = 92/211 (43.60%), Query Frame = 2
Query: 1445 VQLTRSPTKGFGFRLMGG-AEEGCQV--YIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCR---------------------NVLLTRSPEEEFGFVIVSAVNPTE-PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVR 2002
V L RS +GFGF ++ G V YIG +I N P +CGL+ GD I+ +N S + H ++V + ++ +++ + H + I+ ++ +V L R + FGF I + + P + RI A++ L +GD+IL +NG ST G+ + I II+ +I + VR
Sbjct: 1154 VTLARSENEGFGFVIVTSMTRSGSHVGEYIGKLIENSPAQKCGLLRVGDRILSVNGNSVSRMRHEKIVQTIKNCGRNVTLRISPVPEEGGHSGPTSINSYESSDQGSSIRSSNASYQKSDTNSSGDVDFDVTLNRG-SKGFGFSIRGGQDFNKMPLFVLRIADDGPAKQDGRLKVGDKILQINGKSTTGMTHNQAINIIQAGGKSIRLLVR 1363
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000030959.1 (SMESG000030959.1) HSP 1 Score: 103.99 bits (258), Expect = 2.739e-22 Identity = 61/179 (34.08%), Postives = 104/179 (58.10%), Query Frame = 2
Query: 1472 GFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAVNPT-EPCG--IGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
GFGFR++GGAE+ ++ IG ++P+G + G+I GD ++ +N H +VV L++ AA+ G + L +R+S S + ++ D V L RS E FGFVIV+++ + G IG++ S A+KC L +GDRIL+VNG+S + ++ +++ IK+ N+ + +
Sbjct: 1065 GFGFRIIGGAEDNTKITIGPLVPDGAAIRSGMIKEGDELVSVNGAGVVGALHKKVVQLVEAAARL--GSVTLGLRRSS---KSNLTPQRRIPFD---VTLARSENEGFGFVIVTSMTRSGSHVGEYIGKLIENSPAQKCGLLRVGDRILSVNGNSVSRMRHEKIVQTIKNCGRNVTLRI 1235 HSP 2 Score: 71.2478 bits (173), Expect = 2.605e-12 Identity = 55/211 (26.07%), Postives = 92/211 (43.60%), Query Frame = 2
Query: 1445 VQLTRSPTKGFGFRLMGG-AEEGCQV--YIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCR---------------------NVLLTRSPEEEFGFVIVSAVNPTE-PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVR 2002
V L RS +GFGF ++ G V YIG +I N P +CGL+ GD I+ +N S + H ++V + ++ +++ + H + I+ ++ +V L R + FGF I + + P + RI A++ L +GD+IL +NG ST G+ + I II+ +I + VR
Sbjct: 1154 VTLARSENEGFGFVIVTSMTRSGSHVGEYIGKLIENSPAQKCGLLRVGDRILSVNGNSVSRMRHEKIVQTIKNCGRNVTLRISPVPEEGGHSGPTSINSYESSDQGSSIRSSNASYQKSDTNSSGDVDFDVTLNRG-SKGFGFSIRGGQDFNKMPLFVLRIADDGPAKQDGRLKVGDKILQINGKSTTGMTHNQAINIIQAGGKSIRLLVR 1363
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000057909.1 (SMESG000057909.1) HSP 1 Score: 60.4622 bits (145), Expect = 4.765e-10 Identity = 30/76 (39.47%), Postives = 43/76 (56.58%), Query Frame = 2
Query: 1469 KGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVR 1696
+G GF +MGG E+ +YI IIP G D+ G + GD ++ +N S E + H + V LL K+A G + L VR
Sbjct: 98 EGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLL----KAAQGTVKLVVR 169 HSP 2 Score: 51.2174 bits (121), Expect = 6.022e-7 Identity = 25/73 (34.25%), Postives = 41/73 (56.16%), Query Frame = 2
Query: 1784 EEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVR 2002
EE GF ++ P I RI PG VA++ L GD++L+VNG S E H++ + ++K + +++ VR
Sbjct: 97 EEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVR 169
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000009125.1 (SMESG000009125.1) HSP 1 Score: 63.1586 bits (152), Expect = 8.194e-10 Identity = 51/183 (27.87%), Postives = 85/183 (46.45%), Query Frame = 2
Query: 1457 RSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRS-PEEEFGFVIVSAVNPT-EPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITV 1999
+S + G + + G + I ++P +CG I GD+++ ++ EK T +E V LL ++ S L + ++K P S G+ + + V L R P + +G VI + +P I INP SVA +L GD+IL++NG S G +K++ + ITV
Sbjct: 587 QSGSLGINLQALVTRTTGEPLLISKVLPGSAASRCGCIAPGDLLLALDKKPIEKCTLAEAVHLLQNSSDS----LTVRIKKGSPLPKSS-SGTSQSDFGVFTVDLKRELPCQPWGIVISGTDDSIDQPILIDSINPASVASGVSKLSSGDQILSINGHSLRGYTLTQAMKMLHQYPDQVRITV 764 HSP 2 Score: 63.1586 bits (152), Expect = 8.406e-10 Identity = 55/208 (26.44%), Postives = 100/208 (48.08%), Query Frame = 2
Query: 1418 YSQPQETVSVQLTRSPTKGFGFRLMGGAEEGCQVYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSRHEPHSGIHGSLKVERDCRNVLLTRSPEEEFGFVIVSAV--NPTE--PCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIK-HSD---LNIEITVRDGDIN 2017
Y + ++V + + + G + GGA+ G I I P ++ + GD II IN ST H E+V+L+ KS+ K++L + E + I +K+++ + + +E FGFV +P++ P + I PGSVA++ + GD+I++ + L ++VI +++ H D L IE +V D++
Sbjct: 34 YQEKISRINVDIIKKDNETLGLTVSGGADRGETPVIANIRPGSIAERSDIFLIGDHIISINGISTSSLCHQEIVSLV----KSSKPKISLIIDYELPE-KTEIQKEIKIKQASLTLPKSDDVDEGFGFVARGGYCKDPSKMRPLTVMHIRPGSVADRDGRIKPGDKIVSFGNCKVDHLTPENVIALLREHRDKLTLTIEYSVASVDMS 236 HSP 3 Score: 60.077 bits (144), Expect = 8.202e-9 Identity = 34/94 (36.17%), Postives = 52/94 (55.32%), Query Frame = 2
Query: 1724 IHGSLKVERDCRNVLLTR-SPEEEFGFVIVSAVNPTEPCGIGRINPGSVAEKCHELHLGDRILAVNGSSTEGLHYKDVIKIIKHSDLNIEITVR 2002
IH S + R+ + L R +P E FG + ++P + I I P S A +C L+L D I+ VNG STE + DV+ +I S+ N+E+ +R
Sbjct: 1062 IHSSSTLSRNIMTIRLCRKTPTESFGIGVSEGLSP-KGTFISAIKPNSPASRCASLNLYDEIIQVNGLSTENMRCSDVVTLISQSENNLELLIR 1154 HSP 4 Score: 50.8322 bits (120), Expect = 4.793e-6 Identity = 33/93 (35.48%), Postives = 50/93 (53.76%), Query Frame = 2
Query: 1439 VSVQLTR-SPTKGFGFRLMGGAEEGCQ---VYIGAIIPNGPVDQCGLINCGDVIIDINNTSTEKKTHSEVVTLLDEAAKSANGKLNLTVRKSR 1705
++++L R +PT+ FG G EG +I AI PN P +C +N D II +N STE S+VVTL+ ++ + L L +RK +
Sbjct: 1073 MTIRLCRKTPTESFGI----GVSEGLSPKGTFISAIKPNSPASRCASLNLYDEIIQVNGLSTENMRCSDVVTLISQSENN----LELLIRKRK 1157 The following BLAST results are available for this feature:
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30000377 ID=SMED30000377|Name=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2569bpback to top protein sequence of SMED30000377-orf-1 >SMED30000377-orf-1 ID=SMED30000377-orf-1|Name=SMED30000377-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=648bp MLNSNCPSYSTLTRSTESSNTTRESFCTNRHMYSSLNSDPKIKSYLYHIAback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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