Forkhead box protein C2

Overview
NameForkhead box protein C2
Smed IDSMED30000367
Length (bp)1474
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Forkhead box protein C2 (SMED30000367) t-SNE clustered cells

Violin plots show distribution of expression levels for Forkhead box protein C2 (SMED30000367) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Forkhead box protein C2 (SMED30000367) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Forkhead box protein C2 (SMED30000367) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30000367

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynx muscle cellSMED30000367h1SMcG0012283 BK013022smed_ncbi_20240424PMID:33536473
Pascual-Carreras et al., 2021
whole organism asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30000367h1SMcG0012283 SmedASXL_008164SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
muscle cellSMED30000367h1SMcG0012283 dd_Smed_v4_18389_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30000367h1SMcG0012283 dd_Smed_v6_18389_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Forkhead box protein C2 vs. Ensembl Human
Match: FOXC2 (forkhead box C2 [Source:HGNC Symbol;Acc:HGNC:3801])

HSP 1 Score: 177.948 bits (450), Expect = 2.553e-49
Identity = 86/114 (75.44%), Postives = 98/114 (85.96%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATA 922
            + LVKPPYSYIALITMAI + P+ +ITLNGIYQFI +RFP+YRENKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD +   E  A
Sbjct:   68 KDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKEKEERA 181          
BLAST of Forkhead box protein C2 vs. Ensembl Human
Match: FOXC1 (forkhead box C1 [Source:HGNC Symbol;Acc:HGNC:3800])

HSP 1 Score: 175.637 bits (444), Expect = 4.893e-48
Identity = 84/111 (75.68%), Postives = 96/111 (86.49%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAE 913
            + +VKPPYSYIALITMAI + PD +ITLNGIYQFI +RFP+YR+NKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD     E
Sbjct:   74 KDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKE 184          
BLAST of Forkhead box protein C2 vs. Ensembl Human
Match: FOXL1 (forkhead box L1 [Source:HGNC Symbol;Acc:HGNC:3817])

HSP 1 Score: 154.836 bits (390), Expect = 3.425e-42
Identity = 67/98 (68.37%), Postives = 80/98 (81.63%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
            KPPYSYIALI MAI   P+ R+TLNGIYQFI +RFP+Y +N+QGWQNSIRHNLSLN+CF+KV R   R GKGSYWTL P   +MFENG++ RR+R+ K
Sbjct:   49 KPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPK 146          
BLAST of Forkhead box protein C2 vs. Ensembl Human
Match: FOXA3 (forkhead box A3 [Source:HGNC Symbol;Acc:HGNC:5023])

HSP 1 Score: 149.828 bits (377), Expect = 2.489e-40
Identity = 65/114 (57.02%), Postives = 85/114 (74.56%), Query Frame = 2
Query:  590 VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNS 931
             KPPYSYI+LITMAI   P   +TL+ IYQ+I + FPYYREN+Q WQNSIRH+LS N+CF+KV+R   + GKGSYW LHP++ NMFENG +LRR++RFK ++      + A  +
Sbjct:  116 AKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKVKKGGSGAATT 229          
BLAST of Forkhead box protein C2 vs. Ensembl Human
Match: FOXB1 (forkhead box B1 [Source:HGNC Symbol;Acc:HGNC:3799])

HSP 1 Score: 148.673 bits (374), Expect = 3.683e-40
Identity = 64/98 (65.31%), Postives = 78/98 (79.59%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
            KPPYSYI+L  MAI S P+  + L+ IY+FI +RFPYYREN Q WQNS+RHNLS N+CFIK+ R   + GKGS+W LHP+  +MFENGSFLRRR+RFK
Sbjct:   13 KPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFK 110          
BLAST of Forkhead box protein C2 vs. Ensembl Celegans
Match: unc-130 (pep chromosome:WBcel235:II:11281986:11283953:1 gene:WBGene00006853.1 transcript:C47G2.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-130)

HSP 1 Score: 141.739 bits (356), Expect = 6.691e-38
Identity = 62/104 (59.62%), Postives = 79/104 (75.96%), Query Frame = 2
Query:  590 VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDT 901
             KPPYSYIALI M+I + P+ ++TL+ I +FI  +F YY+E    WQNSIRHNLSLN+CF+KV+RG    GKG+YW L PN  +MF+NGSFLRRR+R+K   DT
Sbjct:  126 AKPPYSYIALIAMSILNSPEKKLTLSEICEFIINKFEYYKEKFPAWQNSIRHNLSLNDCFVKVARGPGNPGKGNYWALDPNCEDMFDNGSFLRRRKRYKKNSDT 229          
BLAST of Forkhead box protein C2 vs. Ensembl Celegans
Match: pha-4 (Defective pharyngeal development protein 4 [Source:UniProtKB/Swiss-Prot;Acc:Q17381])

HSP 1 Score: 139.043 bits (349), Expect = 3.173e-36
Identity = 70/138 (50.72%), Postives = 94/138 (68.12%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIIISNSDDLEKVHTSKVENPHSIT 1006
            KPPYSYI+LITMAI      ++TL+ IY +I + FPYY+ N+Q WQNSIRH+LS N+CF+KV+R   + GKGS+WTLH +  NMFENG +LRR++RFK K+   S +    NS   +     + K+   K E+P SIT
Sbjct:  141 KPPYSYISLITMAIQKSNSRQLTLSEIYNWIMDLFPYYQNNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSFWTLHEHCGNMFENGCYLRRQKRFKVKEREPSRKKRNANSQ-QLHQQQHIPKMEI-KEEDPTSIT 276          
BLAST of Forkhead box protein C2 vs. Ensembl Celegans
Match: pha-4 (Defective pharyngeal development protein 4 [Source:UniProtKB/Swiss-Prot;Acc:Q17381])

HSP 1 Score: 139.043 bits (349), Expect = 5.088e-36
Identity = 70/138 (50.72%), Postives = 94/138 (68.12%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIIISNSDDLEKVHTSKVENPHSIT 1006
            KPPYSYI+LITMAI      ++TL+ IY +I + FPYY+ N+Q WQNSIRH+LS N+CF+KV+R   + GKGS+WTLH +  NMFENG +LRR++RFK K+   S +    NS   +     + K+   K E+P SIT
Sbjct:  172 KPPYSYISLITMAIQKSNSRQLTLSEIYNWIMDLFPYYQNNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSFWTLHEHCGNMFENGCYLRRQKRFKVKEREPSRKKRNANSQ-QLHQQQHIPKMEI-KEEDPTSIT 307          
BLAST of Forkhead box protein C2 vs. Ensembl Celegans
Match: pha-4 (Defective pharyngeal development protein 4 [Source:UniProtKB/Swiss-Prot;Acc:Q17381])

HSP 1 Score: 139.043 bits (349), Expect = 1.218e-35
Identity = 70/138 (50.72%), Postives = 94/138 (68.12%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIIISNSDDLEKVHTSKVENPHSIT 1006
            KPPYSYI+LITMAI      ++TL+ IY +I + FPYY+ N+Q WQNSIRH+LS N+CF+KV+R   + GKGS+WTLH +  NMFENG +LRR++RFK K+   S +    NS   +     + K+   K E+P SIT
Sbjct:  236 KPPYSYISLITMAIQKSNSRQLTLSEIYNWIMDLFPYYQNNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSFWTLHEHCGNMFENGCYLRRQKRFKVKEREPSRKKRNANSQ-QLHQQQHIPKMEI-KEEDPTSIT 371          
BLAST of Forkhead box protein C2 vs. Ensembl Celegans
Match: lin-31 (pep chromosome:WBcel235:II:3982549:3986944:1 gene:WBGene00003017.1 transcript:K10G6.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-31)

HSP 1 Score: 124.405 bits (311), Expect = 1.794e-32
Identity = 56/91 (61.54%), Postives = 66/91 (72.53%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFL 865
            KPPYSYI L  MAI    D  + L  IY++I +RFP+YR+N Q WQNS+RHNLS N+CFIK+ R   R GKGSYW +HPNA  MFENGS L
Sbjct:   13 KPPYSYIWLTYMAIQDSDDKMLPLTEIYKYIMDRFPFYRKNTQRWQNSLRHNLSFNDCFIKIPRRADRPGKGSYWAVHPNASGMFENGSCL 103          
BLAST of Forkhead box protein C2 vs. Ensembl Fly
Match: croc (gene:FBgn0014143 transcript:FBtr0078395)

HSP 1 Score: 172.94 bits (437), Expect = 9.415e-48
Identity = 81/108 (75.00%), Postives = 96/108 (88.89%), Query Frame = 2
Query:  572 NDNRSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            + N+ +VKPPYSYIALI MAI +  D ++TLNGIYQ+I ERFPYYR+NKQGWQNSIRHNLSLNECF+KV+R D++ GKGSYWTL P++YNMF+NGSFLRRRRRFK KD
Sbjct:   63 HQNKEIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKD 170          
BLAST of Forkhead box protein C2 vs. Ensembl Fly
Match: fd96Cb (gene:FBgn0004898 transcript:FBtr0084771)

HSP 1 Score: 150.214 bits (378), Expect = 1.666e-41
Identity = 69/126 (54.76%), Postives = 90/126 (71.43%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKY----KDDTISAEATATNSDIIISNSDD 958
            KPPYSYI+L  MAI   P   + L+ IY+FI ++FP+YR+N Q WQNS+RHNLS N+CFIKV R   ++GKGSYWTLHP A++MFENGS LRRR+RF+     KD +    A A N++++    DD
Sbjct:   13 KPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVPRNVTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDISNWKLAAAANTEMVTHYLDD 138          
BLAST of Forkhead box protein C2 vs. Ensembl Fly
Match: fd96Ca (gene:FBgn0004897 transcript:FBtr0339246)

HSP 1 Score: 152.525 bits (384), Expect = 2.165e-41
Identity = 69/113 (61.06%), Postives = 85/113 (75.22%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKY---KDDTISAEATA 922
            KPPYSYI+L  MAI S P+  + L+ IY+FI++RFPYYR+N Q WQNS+RHNLS N+CFIKV R   R GKG+YW LHP A++MFENGS LRRR+RFK      D ++ E TA
Sbjct:   13 KPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLSFNDCFIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTA 125          
BLAST of Forkhead box protein C2 vs. Ensembl Fly
Match: fd96Ca (gene:FBgn0004897 transcript:FBtr0084770)

HSP 1 Score: 152.525 bits (384), Expect = 2.165e-41
Identity = 69/113 (61.06%), Postives = 85/113 (75.22%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKY---KDDTISAEATA 922
            KPPYSYI+L  MAI S P+  + L+ IY+FI++RFPYYR+N Q WQNS+RHNLS N+CFIKV R   R GKG+YW LHP A++MFENGS LRRR+RFK      D ++ E TA
Sbjct:   13 KPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLSFNDCFIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTA 125          
BLAST of Forkhead box protein C2 vs. Ensembl Fly
Match: fkh (gene:FBgn0000659 transcript:FBtr0300259)

HSP 1 Score: 147.517 bits (371), Expect = 1.800e-38
Identity = 62/99 (62.63%), Postives = 81/99 (81.82%), Query Frame = 2
Query:  590 VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
             KPPYSYI+LITMAI + P   +TL+ IYQFI + FP+YR+N+Q WQNSIRH+LS N+CF+K+ R   + GKGS+WTLHP++ NMFENG +LRR++RFK
Sbjct:  209 AKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFK 307          
BLAST of Forkhead box protein C2 vs. Ensembl Zebrafish
Match: foxc1a (forkhead box C1a [Source:NCBI gene;Acc:100148408])

HSP 1 Score: 177.563 bits (449), Expect = 1.342e-49
Identity = 83/105 (79.05%), Postives = 95/105 (90.48%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            + +VKPPYSYIALITMAI + PD ++TLNGIYQFI ERFP+YR+NKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD
Sbjct:   70 KDMVKPPYSYIALITMAIQNSPDKKVTLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD 174          
BLAST of Forkhead box protein C2 vs. Ensembl Zebrafish
Match: foxc1b (forkhead box C1b [Source:NCBI gene;Acc:79375])

HSP 1 Score: 174.096 bits (440), Expect = 1.150e-48
Identity = 83/105 (79.05%), Postives = 94/105 (89.52%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            + +VKPPYSYIALITMAI +  D +ITLNGIYQFI ERFP+YR+NKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD
Sbjct:   70 KDMVKPPYSYIALITMAIQNSSDKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD 174          
BLAST of Forkhead box protein C2 vs. Ensembl Zebrafish
Match: foxl1 (forkhead box L1 [Source:ZFIN;Acc:ZDB-GENE-040426-1181])

HSP 1 Score: 155.992 bits (393), Expect = 1.144e-42
Identity = 69/101 (68.32%), Postives = 81/101 (80.20%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            KPPYSYIALI MAI + PD R TL+GIYQFI +RFPYY +NKQGWQNSIRHNLSLN+CFIKV R   R GKGSYWTL     +MFENG++ RR+R+ + +D
Sbjct:   52 KPPYSYIALIAMAIKNAPDKRATLSGIYQFIMDRFPYYHDNKQGWQNSIRHNLSLNDCFIKVPREKGRPGKGSYWTLDTKCLDMFENGNYRRRKRKCRTQD 152          
BLAST of Forkhead box protein C2 vs. Ensembl Zebrafish
Match: foxl1 (forkhead box L1 [Source:ZFIN;Acc:ZDB-GENE-040426-1181])

HSP 1 Score: 155.992 bits (393), Expect = 1.144e-42
Identity = 69/101 (68.32%), Postives = 81/101 (80.20%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            KPPYSYIALI MAI + PD R TL+GIYQFI +RFPYY +NKQGWQNSIRHNLSLN+CFIKV R   R GKGSYWTL     +MFENG++ RR+R+ + +D
Sbjct:   52 KPPYSYIALIAMAIKNAPDKRATLSGIYQFIMDRFPYYHDNKQGWQNSIRHNLSLNDCFIKVPREKGRPGKGSYWTLDTKCLDMFENGNYRRRKRKCRTQD 152          
BLAST of Forkhead box protein C2 vs. Ensembl Zebrafish
Match: foxa1 (forkhead box A1 [Source:ZFIN;Acc:ZDB-GENE-990415-78])

HSP 1 Score: 151.754 bits (382), Expect = 1.494e-40
Identity = 70/114 (61.40%), Postives = 87/114 (76.32%), Query Frame = 2
Query:  551 NIKMENKNDNRSL--VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
            N   +NK   RS    KPPYSYI+LITMAI   P   +TL+ IYQ+I + FPYYR+N+Q WQNSIRH+LS N+CF+KVSR   + GKGSYWTLHP++ NMFENG +LRR++RFK
Sbjct:  141 NRARDNKTFRRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFK 254          
BLAST of Forkhead box protein C2 vs. Ensembl Xenopus
Match: foxc2 (forkhead box C2 [Source:NCBI gene;Acc:407875])

HSP 1 Score: 178.718 bits (452), Expect = 5.007e-50
Identity = 85/105 (80.95%), Postives = 95/105 (90.48%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            + LVKPPYSYIALITMAI + PD +ITLNGIYQFI +RFP+YRENKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD
Sbjct:   67 KDLVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD 171          
BLAST of Forkhead box protein C2 vs. Ensembl Xenopus
Match: myh10 (myosin, heavy chain 10, non-muscle [Source:Xenbase;Acc:XB-GENE-5957388])

HSP 1 Score: 178.333 bits (451), Expect = 1.553e-49
Identity = 86/121 (71.07%), Postives = 103/121 (85.12%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIII 943
            + +VKPPYSYIALITMAI + P+ +ITLNGIYQFI ERFP+YR+NKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD  +  +AT  + D ++
Sbjct:   75 KDMVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD--VVKDATKEDKDRLL 193          
BLAST of Forkhead box protein C2 vs. Ensembl Xenopus
Match: FOXL1 (forkhead box L1 [Source:HGNC Symbol;Acc:HGNC:3817])

HSP 1 Score: 164.081 bits (414), Expect = 3.207e-45
Identity = 72/98 (73.47%), Postives = 81/98 (82.65%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
            KPPYSYIALI MAI   PDHR+TLNGIYQFI +RFP+Y +NKQGWQNSIRHNLSLN+CFIKV R   R GKGSYWTL P   +MFENG+F RR+R+ K
Sbjct:   51 KPPYSYIALIAMAIKDSPDHRVTLNGIYQFIMDRFPFYHDNKQGWQNSIRHNLSLNDCFIKVPREKGRPGKGSYWTLDPKCLDMFENGNFRRRKRKPK 148          
BLAST of Forkhead box protein C2 vs. Ensembl Xenopus
Match: ventx1.2 (VENT homeobox 1, gene 2 [Source:Xenbase;Acc:XB-GENE-920868])

HSP 1 Score: 150.599 bits (379), Expect = 3.466e-40
Identity = 67/103 (65.05%), Postives = 83/103 (80.58%), Query Frame = 2
Query:  578 NRSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
            N S  KPPYSYI+LITMAI   P+  +TLN IYQ+I + FPYYR+N+Q WQNSIRH+LS N+CF+KV R  ++ GKGSYWTLHP + NMFENG +LRR++RFK
Sbjct:  114 NYSHAKPPYSYISLITMAIQQAPNKMMTLNEIYQWIIDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVPRSPEKPGKGSYWTLHPESGNMFENGCYLRRQKRFK 216          
BLAST of Forkhead box protein C2 vs. Ensembl Xenopus
Match: xk (X-linked Kx blood group [Source:Xenbase;Acc:XB-GENE-1005584])

HSP 1 Score: 150.984 bits (380), Expect = 5.071e-40
Identity = 68/128 (53.12%), Postives = 90/128 (70.31%), Query Frame = 2
Query:  590 VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIIISNSDDLEKVH 973
             KPPYSYI+LITMAI   P   +TL+ IYQ+I + FPYYR+N+Q WQNSIRH+LS N+CF+KV+R   + GKGSYWTLHP++ NMFENG +LRR++RFK +      + +      +   S  L +VH
Sbjct:  157 AKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQQ-GGKGSQDGRKDVSGPSSPLHRVH 283          
BLAST of Forkhead box protein C2 vs. Ensembl Mouse
Match: Foxc2 (forkhead box C2 [Source:MGI Symbol;Acc:MGI:1347481])

HSP 1 Score: 177.948 bits (450), Expect = 1.506e-49
Identity = 84/105 (80.00%), Postives = 95/105 (90.48%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            + LVKPPYSYIALITMAI + P+ +ITLNGIYQFI +RFP+YRENKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD
Sbjct:   67 KDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD 171          
BLAST of Forkhead box protein C2 vs. Ensembl Mouse
Match: Foxc1 (forkhead box C1 [Source:MGI Symbol;Acc:MGI:1347466])

HSP 1 Score: 176.022 bits (445), Expect = 2.478e-48
Identity = 84/111 (75.68%), Postives = 96/111 (86.49%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAE 913
            + +VKPPYSYIALITMAI + PD +ITLNGIYQFI +RFP+YR+NKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD     E
Sbjct:   74 KDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKE 184          
BLAST of Forkhead box protein C2 vs. Ensembl Mouse
Match: Foxl1 (forkhead box L1 [Source:MGI Symbol;Acc:MGI:1347469])

HSP 1 Score: 158.688 bits (400), Expect = 6.418e-44
Identity = 70/109 (64.22%), Postives = 84/109 (77.06%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEAT 919
            KPPYSYIALI MAI   P+ R+TLNGIYQFI +RFP+Y +N+QGWQNSIRHNLSLNECF+KV R   R GKGSYWTL P   +MFENG++ RR+R+ K    +  A+ T
Sbjct:   49 KPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNECFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPAAGSPEAKRT 157          
BLAST of Forkhead box protein C2 vs. Ensembl Mouse
Match: Foxb1 (forkhead box B1 [Source:MGI Symbol;Acc:MGI:1927549])

HSP 1 Score: 148.673 bits (374), Expect = 2.608e-40
Identity = 64/98 (65.31%), Postives = 78/98 (79.59%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
            KPPYSYI+L  MAI S P+  + L+ IY+FI +RFPYYREN Q WQNS+RHNLS N+CFIK+ R   + GKGS+W LHP+  +MFENGSFLRRR+RFK
Sbjct:   13 KPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFK 110          
BLAST of Forkhead box protein C2 vs. Ensembl Mouse
Match: Foxa3 (forkhead box A3 [Source:MGI Symbol;Acc:MGI:1347477])

HSP 1 Score: 149.443 bits (376), Expect = 2.612e-40
Identity = 65/114 (57.02%), Postives = 85/114 (74.56%), Query Frame = 2
Query:  590 VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNS 931
             KPPYSYI+LITMAI   P   +TL+ IYQ+I + FPYYREN+Q WQNSIRH+LS N+CF+KV+R   + GKGSYW LHP++ NMFENG +LRR++RFK ++      +  + S
Sbjct:  118 AKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKAKKGNSATSAS 231          
BLAST of Forkhead box protein C2 vs. UniProt/SwissProt
Match: sp|Q9PVZ3|FXC1A_XENLA (Forkhead box protein C1-A OS=Xenopus laevis OX=8355 GN=foxc1-a PE=2 SV=1)

HSP 1 Score: 180.259 bits (456), Expect = 1.251e-49
Identity = 87/121 (71.90%), Postives = 104/121 (85.95%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIII 943
            + +VKPPYSYIALITMAI + PD +ITLNGIYQFI ERFP+YR+NKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD  +S +AT  + + ++
Sbjct:   75 KDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD--VSKDATKEDKERLL 193          
BLAST of Forkhead box protein C2 vs. UniProt/SwissProt
Match: sp|Q32NP8|FXC1B_XENLA (Forkhead box protein C1-B OS=Xenopus laevis OX=8355 GN=foxc1-b PE=2 SV=1)

HSP 1 Score: 180.259 bits (456), Expect = 1.438e-49
Identity = 87/121 (71.90%), Postives = 104/121 (85.95%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIII 943
            + +VKPPYSYIALITMAI + PD +ITLNGIYQFI ERFP+YR+NKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD  +S +AT  + + ++
Sbjct:   75 KDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD--VSKDATKEDKERLL 193          
BLAST of Forkhead box protein C2 vs. UniProt/SwissProt
Match: sp|Q6NVT7|FOXC2_XENTR (Forkhead box protein C2 OS=Xenopus tropicalis OX=8364 GN=foxc2 PE=2 SV=2)

HSP 1 Score: 179.104 bits (453), Expect = 2.519e-49
Identity = 85/105 (80.95%), Postives = 95/105 (90.48%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            + LVKPPYSYIALITMAI + PD +ITLNGIYQFI +RFP+YRENKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD
Sbjct:   68 KDLVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD 172          
BLAST of Forkhead box protein C2 vs. UniProt/SwissProt
Match: sp|Q9PVY8|FXC2B_XENLA (Forkhead box protein C2-B OS=Xenopus laevis OX=8355 GN=foxc2-b PE=2 SV=2)

HSP 1 Score: 177.563 bits (449), Expect = 6.916e-49
Identity = 85/111 (76.58%), Postives = 97/111 (87.39%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAE 913
            + LVKPPYSYIALITMAI + PD +ITLNGIYQFI +RFP+YRENKQGWQNSIRHNLSLNECF+KV R D++ GKGSYW+L P++YNMFENGSFLRRRRRFK KD +   E
Sbjct:   68 KDLVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWSLDPDSYNMFENGSFLRRRRRFKKKDASREKE 178          
BLAST of Forkhead box protein C2 vs. UniProt/SwissProt
Match: sp|Q68F77|FOXC1_XENTR (Forkhead box protein C1 OS=Xenopus tropicalis OX=8364 GN=foxc1 PE=2 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 8.225e-49
Identity = 86/121 (71.07%), Postives = 103/121 (85.12%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIII 943
            + +VKPPYSYIALITMAI + P+ +ITLNGIYQFI ERFP+YR+NKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD  +  +AT  + D ++
Sbjct:   75 KDMVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD--VVKDATKEDKDRLL 193          
BLAST of Forkhead box protein C2 vs. TrEMBL
Match: A0A087QY64 (Forkhead box protein C2 (Fragment) OS=Aptenodytes forsteri OX=9233 GN=AS27_11365 PE=4 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 1.314e-51
Identity = 81/100 (81.00%), Postives = 91/100 (91.00%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRR 880
            + LVKPPYSYIALITMAI + PD +ITLNGIYQFI +RFP+YRENKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRR
Sbjct:    1 KDLVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRR 100          
BLAST of Forkhead box protein C2 vs. TrEMBL
Match: A0A091USI2 (Forkhead box protein C2 (Fragment) OS=Nipponia nippon OX=128390 GN=Y956_11017 PE=4 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 1.314e-51
Identity = 81/100 (81.00%), Postives = 91/100 (91.00%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRR 880
            + LVKPPYSYIALITMAI + PD +ITLNGIYQFI +RFP+YRENKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRR
Sbjct:    1 KDLVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRR 100          
BLAST of Forkhead box protein C2 vs. TrEMBL
Match: A0A232F827 (Fork-head domain-containing protein OS=Trichomalopsis sarcophagae OX=543379 GN=TSAR_009734 PE=4 SV=1)

HSP 1 Score: 189.119 bits (479), Expect = 1.426e-50
Identity = 82/103 (79.61%), Postives = 94/103 (91.26%), Query Frame = 2
Query:  587 LVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            +VKPPYSYIALITMAI + PD +ITLNGIYQFI ERFPYYRENKQGWQNSIRHNLSLNECF+KV R D++ GKGSYW+L P++YNMF+NGS+LRRRRRFK +D
Sbjct:    1 MVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMERFPYYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWSLDPDSYNMFDNGSYLRRRRRFKKQD 103          
BLAST of Forkhead box protein C2 vs. TrEMBL
Match: Q66S05 (Forkhead box protein C1 OS=Oikopleura dioica OX=34765 GN=008-49 PE=4 SV=1)

HSP 1 Score: 183.726 bits (465), Expect = 2.798e-50
Identity = 87/140 (62.14%), Postives = 111/140 (79.29%), Query Frame = 2
Query:  536 IDNQNNIKMENKNDNRSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIIISNSD 955
            I+++N  KM  K     +VKPPYSYIALI+MAI S+ D RITL+GIY+FIS++FPYYR+ KQGWQNSIRHNLSLNECFIK +R D++ GKGS+WTL P+A+NMFENGS+LRRRRRFK K D +  +A    +  + +NS+
Sbjct:   57 IESKN--KMSAKTSKNEMVKPPYSYIALISMAINSKKDRRITLSGIYKFISDKFPYYRDTKQGWQNSIRHNLSLNECFIKEARIDKKRGKGSFWTLDPDAFNMFENGSYLRRRRRFK-KADALKEKAMNIRNHRLAANSN 193          
BLAST of Forkhead box protein C2 vs. TrEMBL
Match: K7J6X2 (Fork-head domain-containing protein OS=Nasonia vitripennis OX=7425 PE=4 SV=1)

HSP 1 Score: 189.889 bits (481), Expect = 2.807e-50
Identity = 92/145 (63.45%), Postives = 112/145 (77.24%), Query Frame = 2
Query:  461 SASCYNNYQNQFPIINTDSKYPNSPIDNQNNIKMENKNDNRSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            +A  Y   Q ++    T + YP + I +Q +I    K+    +VKPPYSYIALITMAI + PD +ITLNGIYQFI ERFPYYRENKQGWQNSIRHNLSLNECF+KV R D++ GKGSYW+L P++YNMF+NGS+LRRRRRFK +D
Sbjct:   32 AAPSYYEAQYRYGGYATAAGYPVTGI-SQQHIHHPGKD----MVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMERFPYYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWSLDPDSYNMFDNGSYLRRRRRFKKQD 171          
BLAST of Forkhead box protein C2 vs. Ensembl Cavefish
Match: foxc1b (forkhead box C1b [Source:NCBI gene;Acc:79375])

HSP 1 Score: 173.711 bits (439), Expect = 3.799e-51
Identity = 86/114 (75.44%), Postives = 95/114 (83.33%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATA 922
            +  VKPPYSYIALITMAI S  + R+TLNGIYQFI ERFP+YRENKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD     E  A
Sbjct:   68 KDAVKPPYSYIALITMAIQSSAEKRVTLNGIYQFIMERFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVLRDKEERA 181          
BLAST of Forkhead box protein C2 vs. Ensembl Cavefish
Match: FOXC1 (forkhead box C1 [Source:HGNC Symbol;Acc:HGNC:3800])

HSP 1 Score: 177.948 bits (450), Expect = 2.444e-49
Identity = 84/105 (80.00%), Postives = 95/105 (90.48%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            + +VKPPYSYIALITMAI + PD +ITLNGIYQFI ERFP+YR+NKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD
Sbjct:   79 KDMVKPPYSYIALITMAIQNSPDKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD 183          
BLAST of Forkhead box protein C2 vs. Ensembl Cavefish
Match: foxl1 (forkhead box L1 [Source:ZFIN;Acc:ZDB-GENE-040426-1181])

HSP 1 Score: 149.058 bits (375), Expect = 7.482e-42
Identity = 66/98 (67.35%), Postives = 79/98 (80.61%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
            KPPYSYIALI MAI S P+ R TL+GIYQFI + FP+Y +NKQGWQNSIRHNLSLN+CF+KV R   R GKGSYWTL P   +MFENG++ RR+R+ +
Sbjct:   69 KPPYSYIALIAMAIKSAPEERATLSGIYQFIMDNFPFYHDNKQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPKCLDMFENGNYRRRKRKAR 166          
BLAST of Forkhead box protein C2 vs. Ensembl Cavefish
Match: ENSAMXT00000003861.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000133.1:1175856:1177001:-1 gene:ENSAMXG00000003780.2 transcript:ENSAMXT00000003861.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 148.288 bits (373), Expect = 1.022e-41
Identity = 70/127 (55.12%), Postives = 85/127 (66.93%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIIISNSDDLEKVH 973
            KPPYSYI+L  MAI S P+  + L+ IY+FI ERFPYYREN Q WQNS+RHNLS N+CFIK+ R   + GKGS+W LHP   +MFENGSFLRRR+RFK           A  +D +I +    E  H
Sbjct:   13 KPPYSYISLTAMAIQSCPEKMLPLSDIYKFIMERFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPRCGDMFENGSFLRRRKRFK----------VAPAADPLIRSKAAAEAAH 129          
BLAST of Forkhead box protein C2 vs. Ensembl Cavefish
Match: foxa3 (hepatocyte nuclear factor 3-gamma [Source:NCBI gene;Acc:103043939])

HSP 1 Score: 155.221 bits (391), Expect = 1.253e-41
Identity = 80/181 (44.20%), Postives = 107/181 (59.12%), Query Frame = 2
Query:  581 RSL--VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIIISNSDDLEKVHTSKVENPHSITNDFKGLNFSLKKNSTFGDECQEL------FDCQSKES 1099
            RSL   KPPYSYI+LITMAI       +TLN IYQ+I + FPYYREN+Q WQNSIRH+LS N+CF+KV+R   + GKGSYW LHPN+ NMFENG +LRR++RFK +D +     ++  S        + +  H   ++  HS      G + +    S  G   +E        DC S+ +
Sbjct:  136 RSLTHAKPPYSYISLITMAIQQSGSKMLTLNEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPNSGNMFENGCYLRRQKRFKIEDKSAKKSGSSGKSQ----EGGNGKNEHQDGIQEDHSPAAGSDGADSAQSDASHPGSVSEEQQRNLVPLDCPSQAT 312          
BLAST of Forkhead box protein C2 vs. Ensembl Sea Lamprey
Match: FOXC2 (forkhead box C2 [Source:HGNC Symbol;Acc:HGNC:3801])

HSP 1 Score: 171.014 bits (432), Expect = 2.184e-51
Identity = 75/96 (78.12%), Postives = 87/96 (90.62%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLR 868
            + LVKPPYSYIALITMAI S PD ++TLNGIYQFI ++FP+YRENKQGWQNSIRHNLSLNECF+KV R D++ GKGSYW+L P++YNMFENGSFLR
Sbjct:   73 KDLVKPPYSYIALITMAIQSAPDKKVTLNGIYQFIMDKFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWSLDPDSYNMFENGSFLR 168          
BLAST of Forkhead box protein C2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002547.1 (pep scaffold:Pmarinus_7.0:GL485262:1354:7435:1 gene:ENSPMAG00000002324.1 transcript:ENSPMAT00000002547.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 156.377 bits (394), Expect = 5.963e-45
Identity = 68/95 (71.58%), Postives = 81/95 (85.26%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFL 865
            + LVKPPYSYIALI MAI +  + R TL+ IYQFI+ RFP+YRENKQGWQNSIRHNLSLNECF+ V+R D+R GKGS+WTL P+++ MFENGSFL
Sbjct:   22 KDLVKPPYSYIALIAMAIQNSAEGRATLSAIYQFIAGRFPFYRENKQGWQNSIRHNLSLNECFVTVARDDRRPGKGSFWTLDPDSHGMFENGSFL 116          
BLAST of Forkhead box protein C2 vs. Ensembl Sea Lamprey
Match: foxb2 (forkhead box B2 [Source:ZFIN;Acc:ZDB-GENE-081104-320])

HSP 1 Score: 145.591 bits (366), Expect = 9.355e-40
Identity = 64/98 (65.31%), Postives = 76/98 (77.55%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
            KPPYSYI+L  MAI S  +  + L+ IY+FI ERFPYYREN Q WQNS+RHNLS N+CFIK+ R   + GKGS+W LHP   +MFENGSFLRRR+RFK
Sbjct:   13 KPPYSYISLTAMAIQSSAEKMLPLSEIYKFIMERFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPACGDMFENGSFLRRRKRFK 110          
BLAST of Forkhead box protein C2 vs. Ensembl Sea Lamprey
Match: foxf2a (forkhead box F2a [Source:ZFIN;Acc:ZDB-GENE-110407-5])

HSP 1 Score: 138.272 bits (347), Expect = 2.477e-39
Identity = 67/131 (51.15%), Postives = 84/131 (64.12%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTIS---------AEATATNSDIIISNSDD 958
            KPP+SYIALI MAI S P  R+TL+ IYQF+  RFP++R   QGW+NS+RHNLSLNECF+K+ +G  R GKG YWT+ P +  MFE GSF RR R F+ K    S             +T S II +N+  
Sbjct:    6 KPPFSYIALIVMAIQSSPAKRVTLSEIYQFLQGRFPFFRGAYQGWKNSVRHNLSLNECFVKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRLKSRQASPVCRRQRKVGHTLSTISPIITTNTSS 136          
BLAST of Forkhead box protein C2 vs. Ensembl Sea Lamprey
Match: foxf2a (forkhead box F2a [Source:ZFIN;Acc:ZDB-GENE-110407-5])

HSP 1 Score: 135.961 bits (341), Expect = 6.741e-39
Identity = 61/101 (60.40%), Postives = 75/101 (74.26%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            KPP+SYIALI MAI S P  R+TL+ IYQF+  RFP++R   QGW+NS+RHNLSLNECF+K+ +G  R GKG YWT+ P +  MFE GSF RR R F+ K 
Sbjct:    5 KPPFSYIALIVMAIQSSPAKRVTLSEIYQFLQGRFPFFRGAYQGWKNSVRHNLSLNECFVKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRLKS 105          
BLAST of Forkhead box protein C2 vs. Ensembl Yeast
Match: HCM1 (Forkhead transcription factor; drives S-phase activation of genes involved in chromosome segregation, spindle dynamics, budding; also activates genes involved in respiration, use of alternative energy sources (like proline), NAD synthesis, oxidative stress resistance; key factor in early adaptation to nutrient deficiency and diauxic shift; suppressor of calmodulin mutants with specific SPB assembly defects; ortholog of C. elegans lifespan regulator PHA-4 [Source:SGD;Acc:S000000661])

HSP 1 Score: 92.4337 bits (228), Expect = 1.936e-20
Identity = 53/142 (37.32%), Postives = 76/142 (53.52%), Query Frame = 2
Query:  560 MENKNDNRSLVK-PPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIIISNSDDLEKVHTSK 982
            +E +  N  L K PPYSY  LI +AI    + ++TL+ IY +I   FPYY++    WQNSIRHNLSLN+ FIK  +     GKG +W + P A   F    F    R +++  D++         D   S  D+LE+V + +
Sbjct:   97 LERRRINGELAKKPPYSYATLICLAILQSQEGKLTLSQIYHWIHVHFPYYKQKDASWQNSIRHNLSLNDAFIKTEKS--CDGKGHFWEVRPGAETKF----FKGENRGYEFVKDSLQDIGKYFEID---STLDELEQVESGE 229          
BLAST of Forkhead box protein C2 vs. Ensembl Yeast
Match: FKH2 (Forkhead family transcription factor; rate-limiting activator of replication origins; evolutionarily conserved regulator of lifespan; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; positively regulates transcriptional elongation; facilitates clustering, activation of early-firing replication origins; negative role in chromatin silencing at HML and HMR; major role in expression of G2/M phase genes; relocalizes to cytosol under hypoxia [Source:SGD;Acc:S000005012])

HSP 1 Score: 91.6633 bits (226), Expect = 5.013e-20
Identity = 46/87 (52.87%), Postives = 56/87 (64.37%), Query Frame = 2
Query:  563 ENKNDNRSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTL 823
            EN+N     VKPP+SY  +IT AI S P+  I+L  IY++IS  + YYR  K GWQNSIRHNLSLN+ F KV R     GKG  W +
Sbjct:  335 ENRN-----VKPPHSYATMITQAILSSPEGVISLADIYKYISSNYAYYRFAKSGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWRI 416          
BLAST of Forkhead box protein C2 vs. Ensembl Yeast
Match: FKH1 (Forkhead family transcription factor; rate-limiting replication origin activator; evolutionarily conserved lifespan regulator; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; regulates transcription elongation, chromatin silencing at mating loci, expression of G2/M phase genes; facilitates clustering, activation of early-firing replication origins; binds HML recombination enhancer, regulates donor preference during mating-type switching [Source:SGD;Acc:S000001393])

HSP 1 Score: 87.4261 bits (215), Expect = 5.345e-19
Identity = 53/133 (39.85%), Postives = 75/133 (56.39%), Query Frame = 2
Query:  506 NTDSKYPNSPIDNQNNIKMENKND-----NRSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFEN----GSFLRRRR 877
            NT +   N+ + N N   +EN +D     NR  +KPP SY ++IT AI S P+  I+L  IY+FIS+ + +YR ++  WQNS+RHNLSLN+ F KV +   + GKG  W +       F N    G   + RR
Sbjct:  270 NTYTSSSNNAVTNGNVPHIENPSDLSLDENR-YIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRR 401          
BLAST of Forkhead box protein C2 vs. Ensembl Yeast
Match: FHL1 (Regulator of ribosomal protein (RP) transcription; has forkhead associated domain that binds phosphorylated proteins; recruits coactivator Ifh1p or corepressor Crf1p to RP gene promoters; also has forkhead DNA-binding domain though in vitro DNA binding assays give inconsistent results; computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p motifs at others; suppresses RNA pol III and splicing factor prp4 mutants [Source:SGD;Acc:S000006308])

HSP 1 Score: 68.5514 bits (166), Expect = 1.015e-12
Identity = 44/113 (38.94%), Postives = 60/113 (53.10%), Query Frame = 2
Query:  590 VKPPYSYIALITMAITSQPDHR-ITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTIS-AEATA 922
             KP  SY A++T  I      + ++L+ IY  I E FPYY+    GWQ+S+RHNLSLN+ F KVS    + GKG  W L         +  ++  R R K K   I+ A+A A
Sbjct:  460 TKPTVSYSAMLTTCIRKYSTAKGMSLSEIYAGIRELFPYYKYCPDGWQSSVRHNLSLNKSFRKVS----KEGKGWLWGL---------DEEYIAERERQKKKQSEIAVAKAQA 559          
BLAST of Forkhead box protein C2 vs. Ensembl Nematostella
Match: EDO33900 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQU5])

HSP 1 Score: 160.999 bits (406), Expect = 3.379e-44
Identity = 81/136 (59.56%), Postives = 101/136 (74.26%), Query Frame = 2
Query:  587 LVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD--DTISAEATATNSDIIISNSDDLEKVHTSKVE 988
            +VKPPYSYIALI MAI S P+ RITL+GIY FI +RFPYYR NKQGWQNSIRHNLSLNECF+KV R D++ GKGS+W L P++ NMFENGS+LRRR+RF+ KD   ++  E+   +    + NS    +  T+  E
Sbjct:   77 MVKPPYSYIALIAMAIQSAPEKRITLSGIYSFIMDRFPYYRNNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSFWMLDPDSLNMFENGSYLRRRKRFRKKDVQKSMEGESQRKSDGTSVENSTARSETSTTSAE 212          
BLAST of Forkhead box protein C2 vs. Ensembl Nematostella
Match: EDO42492 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1E3])

HSP 1 Score: 152.14 bits (383), Expect = 1.975e-42
Identity = 66/99 (66.67%), Postives = 80/99 (80.81%), Query Frame = 2
Query:  590 VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
             KPPYSYI+LITMAI   P+  +TL+ IYQFI + FPYYR+N+Q WQNSIRH+LS N+CF+KV R   R GKGSYWTLHP+  NMFENG +LRR++RFK
Sbjct:   39 AKPPYSYISLITMAIQQSPNKMLTLSEIYQFIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVPRSPDRPGKGSYWTLHPDCGNMFENGCYLRRQKRFK 137          
BLAST of Forkhead box protein C2 vs. Ensembl Nematostella
Match: EDO39562 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9S5])

HSP 1 Score: 145.206 bits (365), Expect = 3.089e-40
Identity = 69/140 (49.29%), Postives = 94/140 (67.14%), Query Frame = 2
Query:  590 VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIIISNSDDLEKVHTSKVENPHSITN 1009
             KPPYSYI+L  MAI S P   ++L+ IYQFI + FP+YR+N Q WQNS+RHNLS N+CF+K+ R   + GKGS W LHP+   MFENGSFLRRR+RFK +      E T+  + +I +  +D +++  S+ E+  S T 
Sbjct:   12 AKPPYSYISLTAMAIQSSPQKMLSLSEIYQFIMDHFPFYRDNTQRWQNSLRHNLSFNDCFVKIPRRPDQPGKGSLWALHPDCGTMFENGSFLRRRKRFKSER-----ERTSKLAKLISATREDEDELSPSEQESAPSPTG 146          
BLAST of Forkhead box protein C2 vs. Ensembl Nematostella
Match: EDO39529 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9S2])

HSP 1 Score: 137.887 bits (346), Expect = 3.049e-39
Identity = 65/102 (63.73%), Postives = 81/102 (79.41%), Query Frame = 2
Query:  590 VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGD-QRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYK 892
            VKPP+SYIALITM+I + P    TLN IY+FI  RFPY+R+N+Q WQNSIRHNLSLN+CF+KV R    + GKG+YWTLHP+  +MF +GSFLRR +RFK +
Sbjct:   15 VKPPFSYIALITMSIEASPYRMRTLNEIYEFIMTRFPYFRKNQQKWQNSIRHNLSLNDCFVKVPRSIFGKPGKGNYWTLHPSCGDMFGSGSFLRRPKRFKCR 116          
BLAST of Forkhead box protein C2 vs. Ensembl Nematostella
Match: EDO47812 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL76])

HSP 1 Score: 132.109 bits (331), Expect = 2.523e-37
Identity = 59/90 (65.56%), Postives = 70/90 (77.78%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSF 862
            KPPYSY+ALI MAI   P+ R+TLNGIYQ+I  +FPYY +NK+GWQNSIRHNLSLNECFIKV R      KG+YWTL P   +MFE G++
Sbjct:    1 KPPYSYVALIAMAIRESPEKRLTLNGIYQYIISKFPYYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNY 90          
BLAST of Forkhead box protein C2 vs. Ensembl Medaka
Match: foxc1a (forkhead box C1-A [Source:NCBI gene;Acc:111949083])

HSP 1 Score: 176.792 bits (447), Expect = 2.283e-49
Identity = 83/105 (79.05%), Postives = 95/105 (90.48%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            + +VKPPYSYIALITMAI + PD ++TLNGIYQFI ERFP+YR+NKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD
Sbjct:   70 KDMVKPPYSYIALITMAIQNSPDKKVTLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD 174          
BLAST of Forkhead box protein C2 vs. Ensembl Medaka
Match: foxc1 (forkhead box C1 [Source:NCBI gene;Acc:100301605])

HSP 1 Score: 176.022 bits (445), Expect = 2.995e-49
Identity = 83/105 (79.05%), Postives = 95/105 (90.48%), Query Frame = 2
Query:  581 RSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            + +VKPPYSYIALITMAI + P+ +ITLNGIYQFI ERFP+YR+NKQGWQNSIRHNLSLNECF+KV R D++ GKGSYWTL P++YNMFENGSFLRRRRRFK KD
Sbjct:   67 KDMVKPPYSYIALITMAIQNSPEKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD 171          
BLAST of Forkhead box protein C2 vs. Ensembl Medaka
Match: foxl1 (forkhead box L1 [Source:NCBI gene;Acc:100144369])

HSP 1 Score: 150.599 bits (379), Expect = 4.472e-41
Identity = 68/98 (69.39%), Postives = 78/98 (79.59%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
            KPPYSYIALI MAI S P  R TL+GIYQFI +RFP+Y +NKQGWQNSIRHNLSLN+CFIKV R   R GKGSYWTL     +MFENG++ RR+R+ K
Sbjct:   50 KPPYSYIALIAMAIKSAPGQRATLSGIYQFIMDRFPFYHDNKQGWQNSIRHNLSLNDCFIKVPRERGRPGKGSYWTLDTKCLDMFENGNYRRRKRKTK 147          
BLAST of Forkhead box protein C2 vs. Ensembl Medaka
Match: foxb1 (forkhead box B1 [Source:NCBI gene;Acc:100301603])

HSP 1 Score: 149.828 bits (377), Expect = 6.137e-41
Identity = 65/98 (66.33%), Postives = 78/98 (79.59%), Query Frame = 2
Query:  593 KPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
            KPPYSYI+L  MAI S P+  + L+ IY+FI +RFPYYREN Q WQNS+RHNLS N+CFIK+ R   + GKGS+W LHPN  +MFENGSFLRRR+RFK
Sbjct:   13 KPPYSYISLTAMAIQSCPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPNCGDMFENGSFLRRRKRFK 110          
BLAST of Forkhead box protein C2 vs. Ensembl Medaka
Match: ENSORLT00000024271.2 (forkhead box A1 [Source:NCBI gene;Acc:100301627])

HSP 1 Score: 152.14 bits (383), Expect = 7.311e-41
Identity = 77/149 (51.68%), Postives = 101/149 (67.79%), Query Frame = 2
Query:  476 NNYQNQFPIINTDSKYPNSPIDNQNNIKMENKNDNRSL--VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEA 916
            N Y +  P ++    Y  + +    N   +NK   RS    KPPYSYI+LITMAI   P   +TL+ IYQ+I + FPYYR+N+Q WQNSIRH+LS N+CF+KVSR   + GKGSYWTLHP++ NMFENG +LRR++RFK  +  IS +A
Sbjct:  112 NPYGSMSPAMSPSMAYSGAGL----NRARDNKTFRRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKC-EKKISGKA 255          
BLAST of Forkhead box protein C2 vs. Planmine SMEST
Match: SMESG000004239.1 (SMESG000004239.1)

HSP 1 Score: 804.283 bits (2076), Expect = 0.000e+0
Identity = 392/397 (98.74%), Postives = 394/397 (99.24%), Query Frame = 2
Query:  158 MNVDHISVLTAANSAPQIPRHPISDHASLLYYSSAYQFPGCESSSFLWPNSSYNSNSDSWKAAYLNSDPHHLNSYYPSLNSQDVQQDLLFHKSIHSDFYSMSASCYNNYQNQFPIINTDSKYPNSPIDNQNNIKMENKNDNRSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIIISNSDDLEKVHTSKVENPHSITNDFKGLNFSLKKNSTFGDECQELFDCQSKESYSKFINIKPNVIKEIENFDKQAFDFNPNGLYNQFPYFSNISPQNEYPPSNNHLRPPLPYSMNFMQKPNPYLLSNYLSHPQEIS 1348
            MNVDHISVLTAANSAPQIPRHPISDHASLLYYSSAYQFPGCESSSFLWPNSSYNSNSDSWKAAYLNSDPHHLNSYYPSLNSQDVQQDLLFHKSIHSDFYSMSASCYNNYQNQFPIINTDSKYPNSPI+NQNNIK+ENKNDNRSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIIISNSDDLEKVHT KVENPHSITNDFKGLNFSLKKNSTFGDECQELFDCQSKESYSKFINIKPNVIKEIENFDKQAFDFNPNGLYNQFPYFSNISPQNEYP SNNHLRPPLPY MNFMQKPNPYLLSNYLSHPQEIS
Sbjct:    1 MNVDHISVLTAANSAPQIPRHPISDHASLLYYSSAYQFPGCESSSFLWPNSSYNSNSDSWKAAYLNSDPHHLNSYYPSLNSQDVQQDLLFHKSIHSDFYSMSASCYNNYQNQFPIINTDSKYPNSPIENQNNIKIENKNDNRSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAEATATNSDIIISNSDDLEKVHTCKVENPHSITNDFKGLNFSLKKNSTFGDECQELFDCQSKESYSKFINIKPNVIKEIENFDKQAFDFNPNGLYNQFPYFSNISPQNEYPQSNNHLRPPLPYGMNFMQKPNPYLLSNYLSHPQEIS 397          
BLAST of Forkhead box protein C2 vs. Planmine SMEST
Match: SMESG000015673.1 (SMESG000015673.1)

HSP 1 Score: 194.897 bits (494), Expect = 1.435e-56
Identity = 85/109 (77.98%), Postives = 97/109 (88.99%), Query Frame = 2
Query:  569 KNDNRSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKD 895
            +N +R LVKPPYSYIALITMA+ + P+ ++TL+GIYQFI E+FPYYRENKQGWQNSIRHNLSLNECFIK+ R D++ GKGSYW LHP AYNMFENGSFLRRRRRFK KD
Sbjct:   65 RNPSRDLVKPPYSYIALITMAVHAHPEKKVTLSGIYQFIMEKFPYYRENKQGWQNSIRHNLSLNECFIKIPRDDKKPGKGSYWALHPQAYNMFENGSFLRRRRRFKAKD 173          
BLAST of Forkhead box protein C2 vs. Planmine SMEST
Match: SMESG000065670.1 (SMESG000065670.1)

HSP 1 Score: 155.992 bits (393), Expect = 9.206e-42
Identity = 81/160 (50.62%), Postives = 108/160 (67.50%), Query Frame = 2
Query:  527 NSPIDNQNNIKMENKNDNRSL--VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAE----ATATNSDIIISNSDDLEKVHTSKVE 988
            +SP D +N+I   N+   RS    KPPYSYI+LITMAI + P +  TL+ IYQFI + FPYYR+N+Q WQNSIRH+LS N+CF+KVSR  ++ GKGSYWTLHP + NMFENG +LRR++RFK     I  +    AT   S++  +N D+  +  +   E
Sbjct:   85 DSPRD-KNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAE 243          
BLAST of Forkhead box protein C2 vs. Planmine SMEST
Match: SMESG000021434.1 (SMESG000021434.1)

HSP 1 Score: 149.828 bits (377), Expect = 1.929e-41
Identity = 75/140 (53.57%), Postives = 99/140 (70.71%), Query Frame = 2
Query:  587 LVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKY---KDDTISAEATATNSDIIISNSDDLEKVHTSKVENPH 997
            L KPPYSYIALI MAI + PD +ITL+GIY+FI++ FP+Y  NKQGWQNSIRHNLSLN+CFIK++R     GKG+YWTL+ N   MF++G+F RRRR+ K    K D   +E+  T S   + NSD +E  + ++   P+
Sbjct:   62 LEKPPYSYIALIAMAIRNTPDKKITLSGIYKFITDNFPFYHRNKQGWQNSIRHNLSLNDCFIKIARDKNNPGKGNYWTLNENFEEMFDHGNFRRRRRKTKSLTNKQDCQDSESHQTRSCSSV-NSDSIEMRNKTQESTPN 200          
BLAST of Forkhead box protein C2 vs. Planmine SMEST
Match: SMESG000067799.1 (SMESG000067799.1)

HSP 1 Score: 147.517 bits (371), Expect = 1.190e-40
Identity = 71/123 (57.72%), Postives = 91/123 (73.98%), Query Frame = 2
Query:  521 YPN-SPIDNQNNIKMENKNDNRSLVKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFK 886
            +PN SP+D   +    N +   S  KPPYSYI+LITMAI + P    TL+ IYQFI + FPYY++N+Q WQNSIRH+LS N+CFIK SR  ++ GKGS+W LHP++ NMFENG FLRR++RFK
Sbjct:   24 FPNKSPLDASLD---GNSHKRISCSKPPYSYISLITMAIQNSPQKMCTLSEIYQFIMDSFPYYQQNQQRWQNSIRHSLSFNDCFIKASRCTEKPGKGSFWVLHPDSGNMFENGCFLRRQKRFK 143          
The following BLAST results are available for this feature:
BLAST of Forkhead box protein C2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FOXC22.553e-4975.44forkhead box C2 [Source:HGNC Symbol;Acc:HGNC:3801][more]
FOXC14.893e-4875.68forkhead box C1 [Source:HGNC Symbol;Acc:HGNC:3800][more]
FOXL13.425e-4268.37forkhead box L1 [Source:HGNC Symbol;Acc:HGNC:3817][more]
FOXA32.489e-4057.02forkhead box A3 [Source:HGNC Symbol;Acc:HGNC:5023][more]
FOXB13.683e-4065.31forkhead box B1 [Source:HGNC Symbol;Acc:HGNC:3799][more]
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BLAST of Forkhead box protein C2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-1306.691e-3859.62pep chromosome:WBcel235:II:11281986:11283953:1 gen... [more]
pha-43.173e-3650.72Defective pharyngeal development protein 4 [Sourc... [more]
pha-45.088e-3650.72Defective pharyngeal development protein 4 [Sourc... [more]
pha-41.218e-3550.72Defective pharyngeal development protein 4 [Sourc... [more]
lin-311.794e-3261.54pep chromosome:WBcel235:II:3982549:3986944:1 gene:... [more]
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BLAST of Forkhead box protein C2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
croc9.415e-4875.00gene:FBgn0014143 transcript:FBtr0078395[more]
fd96Cb1.666e-4154.76gene:FBgn0004898 transcript:FBtr0084771[more]
fd96Ca2.165e-4161.06gene:FBgn0004897 transcript:FBtr0339246[more]
fd96Ca2.165e-4161.06gene:FBgn0004897 transcript:FBtr0084770[more]
fkh1.800e-3862.63gene:FBgn0000659 transcript:FBtr0300259[more]
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BLAST of Forkhead box protein C2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
foxc1a1.342e-4979.05forkhead box C1a [Source:NCBI gene;Acc:100148408][more]
foxc1b1.150e-4879.05forkhead box C1b [Source:NCBI gene;Acc:79375][more]
foxl11.144e-4268.32forkhead box L1 [Source:ZFIN;Acc:ZDB-GENE-040426-1... [more]
foxl11.144e-4268.32forkhead box L1 [Source:ZFIN;Acc:ZDB-GENE-040426-1... [more]
foxa11.494e-4061.40forkhead box A1 [Source:ZFIN;Acc:ZDB-GENE-990415-7... [more]
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BLAST of Forkhead box protein C2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
foxc25.007e-5080.95forkhead box C2 [Source:NCBI gene;Acc:407875][more]
myh101.553e-4971.07myosin, heavy chain 10, non-muscle [Source:Xenbase... [more]
FOXL13.207e-4573.47forkhead box L1 [Source:HGNC Symbol;Acc:HGNC:3817][more]
ventx1.23.466e-4065.05VENT homeobox 1, gene 2 [Source:Xenbase;Acc:XB-GEN... [more]
xk5.071e-4053.13X-linked Kx blood group [Source:Xenbase;Acc:XB-GEN... [more]
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BLAST of Forkhead box protein C2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Foxc21.506e-4980.00forkhead box C2 [Source:MGI Symbol;Acc:MGI:1347481... [more]
Foxc12.478e-4875.68forkhead box C1 [Source:MGI Symbol;Acc:MGI:1347466... [more]
Foxl16.418e-4464.22forkhead box L1 [Source:MGI Symbol;Acc:MGI:1347469... [more]
Foxb12.608e-4065.31forkhead box B1 [Source:MGI Symbol;Acc:MGI:1927549... [more]
Foxa32.612e-4057.02forkhead box A3 [Source:MGI Symbol;Acc:MGI:1347477... [more]
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BLAST of Forkhead box protein C2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9PVZ3|FXC1A_XENLA1.251e-4971.90Forkhead box protein C1-A OS=Xenopus laevis OX=835... [more]
sp|Q32NP8|FXC1B_XENLA1.438e-4971.90Forkhead box protein C1-B OS=Xenopus laevis OX=835... [more]
sp|Q6NVT7|FOXC2_XENTR2.519e-4980.95Forkhead box protein C2 OS=Xenopus tropicalis OX=8... [more]
sp|Q9PVY8|FXC2B_XENLA6.916e-4976.58Forkhead box protein C2-B OS=Xenopus laevis OX=835... [more]
sp|Q68F77|FOXC1_XENTR8.225e-4971.07Forkhead box protein C1 OS=Xenopus tropicalis OX=8... [more]
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BLAST of Forkhead box protein C2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A087QY641.314e-5181.00Forkhead box protein C2 (Fragment) OS=Aptenodytes ... [more]
A0A091USI21.314e-5181.00Forkhead box protein C2 (Fragment) OS=Nipponia nip... [more]
A0A232F8271.426e-5079.61Fork-head domain-containing protein OS=Trichomalop... [more]
Q66S052.798e-5062.14Forkhead box protein C1 OS=Oikopleura dioica OX=34... [more]
K7J6X22.807e-5063.45Fork-head domain-containing protein OS=Nasonia vit... [more]
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BLAST of Forkhead box protein C2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
foxc1b3.799e-5175.44forkhead box C1b [Source:NCBI gene;Acc:79375][more]
FOXC12.444e-4980.00forkhead box C1 [Source:HGNC Symbol;Acc:HGNC:3800][more]
foxl17.482e-4267.35forkhead box L1 [Source:ZFIN;Acc:ZDB-GENE-040426-1... [more]
ENSAMXT00000003861.21.022e-4155.12pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
foxa31.253e-4144.20hepatocyte nuclear factor 3-gamma [Source:NCBI gen... [more]
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BLAST of Forkhead box protein C2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FOXC22.184e-5178.13forkhead box C2 [Source:HGNC Symbol;Acc:HGNC:3801][more]
ENSPMAT00000002547.15.963e-4571.58pep scaffold:Pmarinus_7.0:GL485262:1354:7435:1 gen... [more]
foxb29.355e-4065.31forkhead box B2 [Source:ZFIN;Acc:ZDB-GENE-081104-3... [more]
foxf2a2.477e-3951.15forkhead box F2a [Source:ZFIN;Acc:ZDB-GENE-110407-... [more]
foxf2a6.741e-3960.40forkhead box F2a [Source:ZFIN;Acc:ZDB-GENE-110407-... [more]
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BLAST of Forkhead box protein C2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4
Match NameE-valueIdentityDescription
HCM11.936e-2037.32Forkhead transcription factor; drives S-phase acti... [more]
FKH25.013e-2052.87Forkhead family transcription factor; rate-limitin... [more]
FKH15.345e-1939.85Forkhead family transcription factor; rate-limitin... [more]
FHL11.015e-1238.94Regulator of ribosomal protein (RP) transcription;... [more]
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BLAST of Forkhead box protein C2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO339003.379e-4459.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO424921.975e-4266.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO395623.089e-4049.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO395293.049e-3963.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO478122.523e-3765.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Forkhead box protein C2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
foxc1a2.283e-4979.05forkhead box C1-A [Source:NCBI gene;Acc:111949083][more]
foxc12.995e-4979.05forkhead box C1 [Source:NCBI gene;Acc:100301605][more]
foxl14.472e-4169.39forkhead box L1 [Source:NCBI gene;Acc:100144369][more]
foxb16.137e-4166.33forkhead box B1 [Source:NCBI gene;Acc:100301603][more]
ENSORLT00000024271.27.311e-4151.68forkhead box A1 [Source:NCBI gene;Acc:100301627][more]
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BLAST of Forkhead box protein C2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000004239.10.000e+098.74SMESG000004239.1[more]
SMESG000015673.11.435e-5677.98SMESG000015673.1[more]
SMESG000065670.19.206e-4250.63SMESG000065670.1[more]
SMESG000021434.11.929e-4153.57SMESG000021434.1[more]
SMESG000067799.11.190e-4057.72SMESG000067799.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30000367 ID=SMED30000367|Name=Forkhead box protein C2|organism=Schmidtea mediterranea sexual|type=transcript|length=1474bp
AAATAATAAGATATTTCAACAAGTGCCAATAGGACAAGTTTCACAATATT
GTTTTTATTATTTATCTTAGATATAGGAGGAAAAAAACTCTTCCCAAAAC
CAATTCTGTCAATTAGAAAAACAAATTTGTTTATTCAAGTTATCCATAAA
GCCGAAAATGAATGTTGATCACATCTCGGTATTAACTGCGGCAAATTCAG
CGCCACAAATTCCGCGCCATCCAATTTCCGATCATGCGTCGTTGTTGTAT
TATTCATCAGCTTATCAATTTCCCGGATGTGAATCTTCGAGCTTCTTGTG
GCCAAATTCTTCATACAATTCTAATTCGGATTCCTGGAAAGCTGCCTACT
TAAATTCAGATCCCCATCATCTAAATTCTTACTATCCATCGTTGAATTCT
CAAGATGTTCAACAAGATTTGCTTTTTCACAAATCAATTCATTCAGATTT
TTATTCCATGTCAGCCTCGTGTTACAATAATTATCAAAACCAATTCCCAA
TCATTAATACCGATTCAAAATATCCTAATTCCCCTATCGATAATCAGAAT
AATATTAAAATGGAGAATAAAAACGATAACAGATCTTTAGTTAAGCCCCC
ATATTCATATATAGCACTGATAACAATGGCAATAACATCTCAACCAGACC
ATCGAATAACTTTGAATGGCATCTATCAGTTTATTTCAGAAAGATTTCCT
TATTATCGTGAGAATAAGCAAGGCTGGCAGAATTCTATTAGGCATAATTT
ATCGCTCAATGAGTGTTTCATTAAGGTATCTAGAGGTGACCAAAGATCTG
GAAAAGGCAGTTATTGGACTTTGCACCCGAATGCATATAATATGTTTGAA
AATGGATCTTTTCTTCGTAGAAGACGCCGTTTTAAGTATAAGGACGATAC
GATATCAGCTGAAGCAACTGCTACAAACTCAGATATAATAATTTCAAATT
CTGATGATCTTGAAAAGGTTCATACATCCAAAGTTGAAAATCCTCATTCT
ATAACAAATGACTTCAAAGGTTTGAATTTTTCATTGAAGAAAAATAGTAC
TTTTGGCGATGAATGTCAAGAACTTTTTGACTGTCAGTCGAAAGAATCAT
ATTCAAAATTCATCAACATTAAGCCGAATGTTATAAAAGAAATAGAGAAT
TTCGACAAACAAGCTTTTGATTTCAATCCTAATGGGTTATACAACCAATT
TCCTTATTTTTCAAATATTAGCCCCCAGAACGAATATCCTCCGTCAAATA
ACCACCTCAGACCTCCATTGCCTTACAGCATGAATTTTATGCAGAAACCG
AATCCATATTTATTGAGCAACTATTTATCTCATCCTCAAGAAATTTCCTG
ACCAATTTTTAGAAATTAATCTGTTTAAATCGTGGTGGTGGTGATGGTTT
TCTAATAAACCATGAAATTCTGCAATTTTTGTTAAATTTTCAGTGCATTT
AATGAATATAAGTTTTTATTTGTG
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protein sequence of SMED30000367-orf-1

>SMED30000367-orf-1 ID=SMED30000367-orf-1|Name=SMED30000367-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=398bp
MNVDHISVLTAANSAPQIPRHPISDHASLLYYSSAYQFPGCESSSFLWPN
SSYNSNSDSWKAAYLNSDPHHLNSYYPSLNSQDVQQDLLFHKSIHSDFYS
MSASCYNNYQNQFPIINTDSKYPNSPIDNQNNIKMENKNDNRSLVKPPYS
YIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSL
NECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTIS
AEATATNSDIIISNSDDLEKVHTSKVENPHSITNDFKGLNFSLKKNSTFG
DECQELFDCQSKESYSKFINIKPNVIKEIENFDKQAFDFNPNGLYNQFPY
FSNISPQNEYPPSNNHLRPPLPYSMNFMQKPNPYLLSNYLSHPQEIS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0001946lymphangiogenesis
GO:0008286insulin receptor signaling pathway
GO:0009725response to hormone
GO:0045893positive regulation of transcription, DNA-templated
GO:0045944positive regulation of transcription from RNA polymerase II promoter
GO:0006355regulation of transcription, DNA-templated
GO:0006351transcription, DNA-templated
GO:0007155cell adhesion
GO:0007275multicellular organism development
GO:0007498mesoderm development
GO:0048793pronephros development
Vocabulary: molecular function
TermDefinition
GO:0031490chromatin DNA binding
GO:1990841promoter-specific chromatin binding
GO:0003700transcription factor activity, sequence-specific DNA binding
GO:0043565sequence-specific DNA binding
GO:0003677DNA binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR036388WH-like_DNA-bd_sf
IPR036390WH_DNA-bd_sf
IPR001766Fork_head_dom
IPR011991WHTH_DNA-bd_dom
IPR030456TF_fork_head_CS_2
IPR018122TF_fork_head_CS_1
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001766Fork head domainPRINTSPR00053FORKHEADcoord: 146..159
score: 79.2
coord: 190..207
score: 79.54
coord: 167..184
score: 56.61
IPR001766Fork head domainSMARTSM00339forkneu4coord: 144..234
e-value: 4.0E-56
score: 202.5
IPR001766Fork head domainPFAMPF00250Forkheadcoord: 146..231
e-value: 8.4E-39
score: 131.7
IPR001766Fork head domainPROSITEPS50039FORK_HEAD_3coord: 146..240
score: 39.276
IPR001766Fork head domainCDDcd00059FHcoord: 146..223
e-value: 1.98583E-45
score: 149.241
IPR036388Winged helix-like DNA-binding domain superfamilyGENE3DG3DSA:1.10.10.10coord: 145..245
e-value: 8.7E-46
score: 156.1
NoneNo IPR availablePANTHERPTHR11829FORKHEAD BOX PROTEINcoord: 38..292
IPR030456Fork head domain conserved site 2PROSITEPS00658FORK_HEAD_2coord: 190..196
IPR018122Fork head domain conserved site1PROSITEPS00657FORK_HEAD_1coord: 146..159
IPR036390Winged helix DNA-binding domain superfamilySUPERFAMILYSSF46785"Winged helix" DNA-binding domaincoord: 145..240