HoxC12-like protein

Overview


Name	HoxC12-like protein
Smed ID	SMED30000303
Length (bp)	806

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of HoxC12-like protein (SMED30000303) t-SNE clustered cells

Violin plots show distribution of expression levels for HoxC12-like protein (SMED30000303) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of HoxC12-like protein (SMED30000303) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for HoxC12-like protein (SMED30000303) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30000303

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 25

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
posterior region of the whole animal	SMED30000303	h1SMcG0009116	dd_Smed_v4_12467_0_1	dd_Smed_v4	PMID:27063937 Scimone et al., 2016
posterior region of the whole animal	SMED30000303	h1SMcG0009116	dd_Smed_v4_12467_0_1	dd_Smed_v4	PMID:27063937 Scimone et al., 2016
tail region	SMED30000303	h1SMcG0009116	dd_Smed_v4_12467_0_1	dd_Smed_v4	PMID:27063937 Scimone et al., 2016
mouth	SMED30000303	h1SMcG0009116	SmedASXL_007760	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
posterior region of the whole animal	SMED30000303	h1SMcG0009116	SmedASXL_007760	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
posterior region of the whole animal	SMED30000303	h1SMcG0009116	SmedASXL_007760	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
posterior region of the whole animal	SMED30000303	h1SMcG0009116	SmedASXL_007760	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
prepharyngeal region	SMED30000303	h1SMcG0009116	SmedASXL_007760	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
prepharyngeal region	SMED30000303	h1SMcG0009116	SmedASXL_007760	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
parapharyngeal region	SMED30000303	h1SMcG0009116	SmedASXL_007760	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
parapharyngeal region	SMED30000303	h1SMcG0009116	SmedASXL_007760	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
tail region	SMED30000303	h1SMcG0009116	SmedASXL_007760	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
tail region	SMED30000303	h1SMcG0009116	SmedASXL_007760	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
posterior region of the whole animal	SMED30000303	h1SMcG0009116	Smed-Post-2c	smed_ncbi_20240424	PMID:27034770 Currie et al., 2016
X1 cell	SMED30000303	h1SMcG0009116	SmedASXL_007760	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
Category 2 cell	SMED30000303	h1SMcG0009116	SMED30000303	smed_20140614	PMID:29100657 Cheng et al., 2018
epidermis	SMED30000303	h1SMcG0009116	SMED30000303	smed_20140614	PMID:29100657 Cheng et al., 2018
Category 3 cell	SMED30000303	h1SMcG0009116	SMED30000303	smed_20140614	PMID:29100657 Cheng et al., 2018
tail region	SMED30000303	h1SMcG0009116	SMED30000303	smed_20140614	PMID:29100657 Cheng et al., 2018
neoblast	SMED30000303	h1SMcG0009116	SMED30000303	smed_20140614	PMID:29100657 Cheng et al., 2018
X1 cell	SMED30000303	h1SMcG0009116	SMED30000303	smed_20140614	PMID:29100657 Cheng et al., 2018
posterior side	SMED30000303	h1SMcG0009116	dd_Smed_v4_12467_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior muscle cell	SMED30000303	h1SMcG0009116	dd_Smed_v4_12467_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
tail region	SMED30000303	h1SMcG0009116	dd_Smed_v6_12467_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
tail region	SMED30000303	h1SMcG0009116	dd_Smed_v6_12467_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of HoxC12-like protein vs. Ensembl Human
Match: HOXC12 (homeobox C12 [Source:HGNC Symbol;Acc:HGNC:5124])

HSP 1 Score: 77.0258 bits (188), Expect = 6.026e-16
Identity = 32/61 (52.46%), Postives = 49/61 (80.33%), Query Frame = 1

Query:  460 DQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            + + R KR+PYS+ QL  LE E++  E+I+RQ+R +++ +LNLS++Q+KIWFQNRRMK K+
Sbjct:  211 NSRSRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 271

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BLAST of HoxC12-like protein vs. Ensembl Human
Match: HOXD12 (homeobox D12 [Source:HGNC Symbol;Acc:HGNC:5135])

HSP 1 Score: 74.7146 bits (182), Expect = 3.492e-15
Identity = 31/59 (52.54%), Postives = 49/59 (83.05%), Query Frame = 1

Query:  466 KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            + R KR+PY++ Q+  LE+E++  E+I+RQKR +++ +LNLS++Q+KIWFQNRRMK K+
Sbjct:  201 RARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 259

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BLAST of HoxC12-like protein vs. Ensembl Human
Match: HOXB9 (homeobox B9 [Source:HGNC Symbol;Acc:HGNC:5120])

HSP 1 Score: 74.3294 bits (181), Expect = 4.243e-15
Identity = 36/62 (58.06%), Postives = 48/62 (77.42%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK 654
            R KR PY++YQ + LE E++   Y++R +R ++A  LNLSERQ+KIWFQNRRMK KK NKE+
Sbjct:  186 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQ 247

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BLAST of HoxC12-like protein vs. Ensembl Human
Match: AC004080.3 (HOXA10-HOXA9 readthrough)

HSP 1 Score: 70.0922 bits (170), Expect = 1.053e-14
Identity = 33/62 (53.23%), Postives = 49/62 (79.03%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK 654
            R KR PY+++Q + LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK NK++
Sbjct:   47 RKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDR 108

[Close]

BLAST of HoxC12-like protein vs. Ensembl Human
Match: HOXA9 (homeobox A9 [Source:HGNC Symbol;Acc:HGNC:5109])

HSP 1 Score: 72.0182 bits (175), Expect = 1.401e-14
Identity = 33/62 (53.23%), Postives = 49/62 (79.03%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK 654
            R KR PY+++Q + LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK NK++
Sbjct:  148 RKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDR 209

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BLAST of HoxC12-like protein vs. Ensembl Celegans
Match: php-3 (Posterior Hox gene Paralog [Source:UniProtKB/TrEMBL;Acc:Q9XW88])

HSP 1 Score: 82.0333 bits (201), Expect = 3.874e-18
Identity = 40/89 (44.94%), Postives = 59/89 (66.29%), Query Frame = 1

Query:  394 FVSENLPSSCPNSNKSVEKE--EKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK 654
            F + ++PS   N N   + E        R KR+PY++ Q + LE E++   Y+S+QKRW++A  L+L+ERQ+KIWFQNRRMK KK K++
Sbjct:  172 FANYSMPSLDGNLNDGGQLEWTSSSHAMRKKRKPYTKAQTLELEKEFLYNTYVSKQKRWELAKYLHLTERQVKIWFQNRRMKDKKQKQR 260

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Query:  394 FVSENLPSSCPNSNKSVEKE--EKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK 654
            F + ++PS   N N   + E        R KR+PY++ Q + LE E++   Y+S+QKRW++A  L+L+ERQ+KIWFQNRRMK KK K++
Sbjct:  172 FANYSMPSLDGNLNDGGQLEWTSSSHAMRKKRKPYTKAQTLELEKEFLYNTYVSKQKRWELAKYLHLTERQVKIWFQNRRMKDKKQKQR 260

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BLAST of HoxC12-like protein vs. Ensembl Celegans
Match: lin-39 (Homeobox protein lin-39 [Source:UniProtKB/Swiss-Prot;Acc:P34684])

HSP 1 Score: 73.1738 bits (178), Expect = 5.031e-15
Identity = 37/81 (45.68%), Postives = 56/81 (69.14%), Query Frame = 1

Query:  463 QKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK*TLPRILCR*LPITAN 702
            + E+ +R  Y+R Q++ LE E+   +Y++R++R ++A  L L+ERQ+KIWFQNRRMKHKK NK+K   P +    +P  AN
Sbjct:  163 RGEKRQRTAYTRNQVLELEKEFHTHKYLTRKRRIEVAHSLMLTERQVKIWFQNRRMKHKKENKDKPMTPPM----MPFGAN 239

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Query:  463 QKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK*TLPRILCR*LPITAN 702
            + E+ +R  Y+R Q++ LE E+   +Y++R++R ++A  L L+ERQ+KIWFQNRRMKHKK NK+K   P +    +P  AN
Sbjct:  163 RGEKRQRTAYTRNQVLELEKEFHTHKYLTRKRRIEVAHSLMLTERQVKIWFQNRRMKHKKENKDKPMTPPM----MPFGAN 239

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BLAST of HoxC12-like protein vs. Ensembl Celegans
Match: mab-5 (Homeobox protein mab-5 [Source:UniProtKB/Swiss-Prot;Acc:P10038])

HSP 1 Score: 66.2402 bits (160), Expect = 5.684e-13
Identity = 31/62 (50.00%), Postives = 46/62 (74.19%), Query Frame = 1

Query:  457 KDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            K  + +  R+ YSR Q + LE E+   +Y++R++R +I+  L+L+ERQ+KIWFQNRRMKHKK
Sbjct:  113 KGGESKRTRQTYSRSQTLELEKEFHYHKYLTRKRRQEISETLHLTERQVKIWFQNRRMKHKK 174

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BLAST of HoxC12-like protein vs. Ensembl Fly
Match: Abd-B (gene:FBgn0000015 transcript:FBtr0346764)

HSP 1 Score: 80.4925 bits (197), Expect = 1.800e-17
Identity = 34/57 (59.65%), Postives = 47/57 (82.46%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR+PYS++Q + LE E++   Y+S+QKRW++A  L L+ERQ+KIWFQNRRMK+KK
Sbjct:  165 RKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKK 221

[Close]

BLAST of HoxC12-like protein vs. Ensembl Fly
Match: Abd-B (gene:FBgn0000015 transcript:FBtr0083381)

HSP 1 Score: 80.1073 bits (196), Expect = 1.964e-17
Identity = 34/57 (59.65%), Postives = 47/57 (82.46%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR+PYS++Q + LE E++   Y+S+QKRW++A  L L+ERQ+KIWFQNRRMK+KK
Sbjct:  165 RKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKK 221

[Close]

BLAST of HoxC12-like protein vs. Ensembl Fly
Match: Abd-B (gene:FBgn0000015 transcript:FBtr0083382)

HSP 1 Score: 80.1073 bits (196), Expect = 1.964e-17
Identity = 34/57 (59.65%), Postives = 47/57 (82.46%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR+PYS++Q + LE E++   Y+S+QKRW++A  L L+ERQ+KIWFQNRRMK+KK
Sbjct:  165 RKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKK 221

[Close]

BLAST of HoxC12-like protein vs. Ensembl Fly
Match: Abd-B (gene:FBgn0000015 transcript:FBtr0415465)

HSP 1 Score: 80.1073 bits (196), Expect = 1.964e-17
Identity = 34/57 (59.65%), Postives = 47/57 (82.46%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR+PYS++Q + LE E++   Y+S+QKRW++A  L L+ERQ+KIWFQNRRMK+KK
Sbjct:  165 RKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKK 221

[Close]

BLAST of HoxC12-like protein vs. Ensembl Fly
Match: Abd-B (gene:FBgn0000015 transcript:FBtr0083385)

HSP 1 Score: 80.1073 bits (196), Expect = 1.964e-17
Identity = 34/57 (59.65%), Postives = 47/57 (82.46%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR+PYS++Q + LE E++   Y+S+QKRW++A  L L+ERQ+KIWFQNRRMK+KK
Sbjct:  165 RKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKK 221

[Close]

BLAST of HoxC12-like protein vs. Ensembl Zebrafish
Match: hoxd9a (homeobox D9a [Source:NCBI gene;Acc:30350])

HSP 1 Score: 78.1814 bits (191), Expect = 1.401e-16
Identity = 46/108 (42.59%), Postives = 66/108 (61.11%), Query Frame = 1

Query:  382 SADKFVSENLPSSCPNSNKSVEKEEKDQKE----------------RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK 654
            SADK   E + S   NS+    K+EK Q++                R KR PY++YQ + LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK N+E+
Sbjct:  152 SADKATEERVGSD--NSSHGEPKDEKQQQQLDPSNPAANWIHARSTRKKRCPYTKYQTLELEKEFLYNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMNRER 257

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BLAST of HoxC12-like protein vs. Ensembl Zebrafish
Match: hoxc12a (homeobox C12a [Source:ZFIN;Acc:ZDB-GENE-000822-6])

HSP 1 Score: 75.485 bits (184), Expect = 1.524e-15
Identity = 32/59 (54.24%), Postives = 48/59 (81.36%), Query Frame = 1

Query:  466 KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            + R KR+PYS+ QL  LE E++  E+I+RQ+R +++ +LNLS++Q+KIWFQNRRMK K+
Sbjct:  205 RTRKKRKPYSKLQLAELEGEFMLNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 263

[Close]

BLAST of HoxC12-like protein vs. Ensembl Zebrafish
Match: hoxc12b (homeobox C12b [Source:NCBI gene;Acc:58062])

HSP 1 Score: 74.7146 bits (182), Expect = 2.588e-15
Identity = 32/60 (53.33%), Postives = 49/60 (81.67%), Query Frame = 1

Query:  463 QKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            ++ R KR+PYS+ QL  LE E+I  E+I+RQ+R +++ +LNL+++Q+KIWFQNRRMK K+
Sbjct:  213 RQTRKKRKPYSKLQLNELEGEFILNEFITRQRRRELSDRLNLTDQQVKIWFQNRRMKKKR 272

[Close]

BLAST of HoxC12-like protein vs. Ensembl Zebrafish
Match: hoxa9a (homeobox A9a [Source:NCBI gene;Acc:58047])

HSP 1 Score: 74.3294 bits (181), Expect = 3.042e-15
Identity = 31/57 (54.39%), Postives = 46/57 (80.70%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR PY+++Q++ LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK
Sbjct:  185 RKKRCPYTKHQILELEKEFLFNTYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKK 241

[Close]

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR PY+++Q++ LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK
Sbjct:  185 RKKRCPYTKHQILELEKEFLFNTYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKK 241

[Close]

BLAST of HoxC12-like protein vs. Ensembl Xenopus
Match: irs1 (insulin receptor substrate 1 [Source:Xenbase;Acc:XB-GENE-478672])

HSP 1 Score: 75.0998 bits (183), Expect = 2.865e-15
Identity = 38/88 (43.18%), Postives = 54/88 (61.36%), Query Frame = 1

Query:  379 SSADKFVSENLPSSCPNSNKSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            S+ DK V+ +     P+           Q+ R KR PYS+YQ+  LE E+    YI+++KR  ++  LNL++RQ+KIWFQNRRMK KK
Sbjct:  172 STQDKKVTNDSSPGTPSGEAEKSNSSASQRLRKKRCPYSKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 259

[Close]

BLAST of HoxC12-like protein vs. Ensembl Xenopus
Match: ache (acetylcholinesterase (Cartwright blood group) [Source:Xenbase;Acc:XB-GENE-923160])

HSP 1 Score: 73.1738 bits (178), Expect = 1.025e-14
Identity = 35/62 (56.45%), Postives = 48/62 (77.42%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK 654
            R KR PY++YQ + LE E++   Y++R +R ++A  LNLSERQ+KIWFQNRRMK KK NK++
Sbjct:  182 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKLNKDQ 243

[Close]

BLAST of HoxC12-like protein vs. Ensembl Xenopus
Match: syt8 (synaptotagmin 8 [Source:Xenbase;Acc:XB-GENE-978920])

HSP 1 Score: 73.1738 bits (178), Expect = 1.031e-14
Identity = 31/59 (52.54%), Postives = 48/59 (81.36%), Query Frame = 1

Query:  466 KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            + R KR+PYS+ QL  LE E++  E+I+RQ+R +++ +L+LS++Q+KIWFQNRRMK K+
Sbjct:  194 RSRKKRKPYSKIQLAELEGEFMVNEFITRQRRRELSDRLSLSDQQVKIWFQNRRMKKKR 252

[Close]

BLAST of HoxC12-like protein vs. Ensembl Xenopus
Match: ENSXETT00000012532.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:6:32900780:32902234:1 gene:ENSXETG00000005181.1 transcript:ENSXETT00000012532.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.7886 bits (177), Expect = 1.838e-14
Identity = 33/62 (53.23%), Postives = 49/62 (79.03%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK 654
            R KR PY+++Q + LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK NK++
Sbjct:  196 RKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDR 257

[Close]

BLAST of HoxC12-like protein vs. Ensembl Xenopus
Match: hoxc8 (homeobox C8 [Source:NCBI gene;Acc:448482])

HSP 1 Score: 72.0182 bits (175), Expect = 2.213e-14
Identity = 33/65 (50.77%), Postives = 47/65 (72.31%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK*TLP 666
            R+ R+ YSRYQ + LE E++   Y++R++R +++  L L+ERQ+KIWFQNRRMK KK   K  LP
Sbjct:  150 RSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLP 214

[Close]

BLAST of HoxC12-like protein vs. Ensembl Mouse
Match: Hoxc12 (homeobox C12 [Source:MGI Symbol;Acc:MGI:96194])

HSP 1 Score: 76.6406 bits (187), Expect = 6.372e-16
Identity = 32/59 (54.24%), Postives = 48/59 (81.36%), Query Frame = 1

Query:  466 KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            + R KR+PYS+ QL  LE E++  E+I+RQ+R +++ +LNLS++Q+KIWFQNRRMK K+
Sbjct:  211 RSRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 269

[Close]

BLAST of HoxC12-like protein vs. Ensembl Mouse
Match: Hoxb9 (homeobox B9 [Source:MGI Symbol;Acc:MGI:96190])

HSP 1 Score: 74.3294 bits (181), Expect = 2.637e-15
Identity = 36/62 (58.06%), Postives = 48/62 (77.42%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK 654
            R KR PY++YQ + LE E++   Y++R +R ++A  LNLSERQ+KIWFQNRRMK KK NKE+
Sbjct:  186 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQ 247

[Close]

BLAST of HoxC12-like protein vs. Ensembl Mouse
Match: Hoxd12 (homeobox D12 [Source:MGI Symbol;Acc:MGI:96204])

HSP 1 Score: 74.7146 bits (182), Expect = 2.740e-15
Identity = 31/59 (52.54%), Postives = 49/59 (83.05%), Query Frame = 1

Query:  466 KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            + R KR+PY++ Q+  LE+E++  E+I+RQKR +++ +LNLS++Q+KIWFQNRRMK K+
Sbjct:  199 RARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 257

[Close]

BLAST of HoxC12-like protein vs. Ensembl Mouse
Match: Hoxa9 (homeobox A9 [Source:MGI Symbol;Acc:MGI:96180])

HSP 1 Score: 72.7886 bits (177), Expect = 1.421e-14
Identity = 33/62 (53.23%), Postives = 49/62 (79.03%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK 654
            R KR PY+++Q + LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK NK++
Sbjct:  206 RKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDR 267

[Close]

BLAST of HoxC12-like protein vs. Ensembl Mouse
Match: Hoxc8 (homeobox C8 [Source:MGI Symbol;Acc:MGI:96198])

HSP 1 Score: 72.4034 bits (176), Expect = 1.444e-14
Identity = 33/65 (50.77%), Postives = 47/65 (72.31%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK*TLP 666
            R+ R+ YSRYQ + LE E++   Y++R++R +++  L L+ERQ+KIWFQNRRMK KK   K  LP
Sbjct:  150 RSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLP 214

[Close]

BLAST of HoxC12-like protein vs. UniProt/SwissProt
Match: sp|P09087|ABDB_DROME (Homeobox protein abdominal-B OS=Drosophila melanogaster OX=7227 GN=Abd-B PE=1 SV=3)

HSP 1 Score: 81.6481 bits (200), Expect = 3.104e-16
Identity = 34/57 (59.65%), Postives = 47/57 (82.46%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR+PYS++Q + LE E++   Y+S+QKRW++A  L L+ERQ+KIWFQNRRMK+KK
Sbjct:  388 RKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKK 444

[Close]

BLAST of HoxC12-like protein vs. UniProt/SwissProt
Match: sp|Q9PWM6|HXD9A_DANRE (Homeobox protein Hox-D9a OS=Danio rerio OX=7955 GN=hoxd9a PE=2 SV=2)

HSP 1 Score: 78.1814 bits (191), Expect = 1.058e-15
Identity = 46/108 (42.59%), Postives = 66/108 (61.11%), Query Frame = 1

Query:  382 SADKFVSENLPSSCPNSNKSVEKEEKDQKE----------------RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK 654
            SADK   E + S   NS+    K+EK Q++                R KR PY++YQ + LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK N+E+
Sbjct:  152 SADKATEERVGSD--NSSHGEPKDEKQQQQLDPSNPAANWIHARSTRKKRCPYTKYQTLELEKEFLYNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMNRER 257

[Close]

BLAST of HoxC12-like protein vs. UniProt/SwissProt
Match: sp|P31275|HXC12_HUMAN (Homeobox protein Hox-C12 OS=Homo sapiens OX=9606 GN=HOXC12 PE=3 SV=2)

HSP 1 Score: 77.0258 bits (188), Expect = 2.894e-15
Identity = 32/61 (52.46%), Postives = 49/61 (80.33%), Query Frame = 1

Query:  460 DQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            + + R KR+PYS+ QL  LE E++  E+I+RQ+R +++ +LNLS++Q+KIWFQNRRMK K+
Sbjct:  211 NSRSRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 271

[Close]

BLAST of HoxC12-like protein vs. UniProt/SwissProt
Match: sp|Q8K5B8|HXC12_MOUSE (Homeobox protein Hox-C12 OS=Mus musculus OX=10090 GN=Hoxc12 PE=2 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 4.457e-15
Identity = 32/59 (54.24%), Postives = 48/59 (81.36%), Query Frame = 1

Query:  466 KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            + R KR+PYS+ QL  LE E++  E+I+RQ+R +++ +LNLS++Q+KIWFQNRRMK K+
Sbjct:  211 RSRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 269

[Close]

BLAST of HoxC12-like protein vs. UniProt/SwissProt
Match: sp|P48590|FTZ_DROHY (Segmentation protein fushi tarazu OS=Drosophila hydei OX=7224 GN=ftz PE=3 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 4.848e-15
Identity = 41/71 (57.75%), Postives = 53/71 (74.65%), Query Frame = 1

Query:  436 KSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNK 648
            +++  + KD K RT R+ YSRYQ + LE E+    YI+R++R DIA  LNLSERQIKIWFQNRRMK KK++
Sbjct:  274 ETIASDCKDSK-RT-RQTYSRYQTLELEKEFHFNRYITRRRRMDIAHALNLSERQIKIWFQNRRMKSKKDR 342

[Close]

BLAST of HoxC12-like protein vs. TrEMBL
Match: A0A165FWV6 (HoxC12-like protein OS=Schmidtea mediterranea OX=79327 GN=hoxC12 PE=2 SV=1)

HSP 1 Score: 337.035 bits (863), Expect = 2.620e-115
Identity = 163/163 (100.00%), Postives = 163/163 (100.00%), Query Frame = 1

Query:  166 MIHDNDNYIYHHNWAPESPIYTPQYEWHPLGPIKESISGFPDYIPHVKESFHSSFNHLSFRYPQAIQPVSLSSADKFVSENLPSSCPNSNKSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK 654
            MIHDNDNYIYHHNWAPESPIYTPQYEWHPLGPIKESISGFPDYIPHVKESFHSSFNHLSFRYPQAIQPVSLSSADKFVSENLPSSCPNSNKSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK
Sbjct:    1 MIHDNDNYIYHHNWAPESPIYTPQYEWHPLGPIKESISGFPDYIPHVKESFHSSFNHLSFRYPQAIQPVSLSSADKFVSENLPSSCPNSNKSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK 163

[Close]

BLAST of HoxC12-like protein vs. TrEMBL
Match: Q9BLF9 (Hox class homeodomain protein DjAbd-Ba OS=Dugesia japonica OX=6161 GN=DjAbd-Ba PE=2 SV=1)

HSP 1 Score: 113.235 bits (282), Expect = 7.549e-26
Identity = 55/104 (52.88%), Postives = 71/104 (68.27%), Query Frame = 1

Query:  343 FRYPQAIQPVSLSSADKFVSENLPSSCPNSNKSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK 654
            +R PQ     + +S     + N+ S+  +  KS  K  +  K R KR+PYSRYQ M+LESEY+   YI+RQKRW+IACKL+LSERQIK+WFQNRRMK KK K +
Sbjct:  152 YRLPQTATSTAANSQSDSGNSNICSTTKSITKSENKSSETVKTRKKRKPYSRYQTMILESEYVGNTYITRQKRWEIACKLHLSERQIKVWFQNRRMKTKKIKNR 255

[Close]

BLAST of HoxC12-like protein vs. TrEMBL
Match: B6RFY1 (Post2 hox protein OS=Capitella teleta OX=283909 PE=2 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 3.352e-25
Identity = 65/146 (44.52%), Postives = 92/146 (63.01%), Query Frame = 1

Query:  238 YEWHPLG--PIKESISGFPDYIPHVKESFH--SSFNHLSFRYPQAIQPV-SLSSADKFVSENLP--SSCPNSNKSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK 654
            ++ +PL   P   +I+ FP Y P V   +H  +S NH +         + S+ S  +F S+ +P  +  PNS     +     K+R KR+PY+RYQ MVLE+E+IN  YI+RQKRW+I+CKL+LSERQ+K+WFQNRRMK KK  E+
Sbjct:  122 HQLNPLNSLPPPRNIANFPFYSPEV---YHQAASANHGAMSGAGLFSDIPSIPSMTRFDSDGVPPYAVDPNS-----QNPDAPKQRKKRKPYTRYQTMVLENEFINNSYITRQKRWEISCKLHLSERQVKVWFQNRRMKRKKLNER 259

[Close]

BLAST of HoxC12-like protein vs. TrEMBL
Match: R7UM68 (Post2 hox protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_126009 PE=4 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 9.468e-23
Identity = 44/63 (69.84%), Postives = 56/63 (88.89%), Query Frame = 1

Query:  466 KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK 654
            K+R KR+PY+RYQ MVLE+E+IN  YI+RQKRW+I+CKL+LSERQ+K+WFQNRRMK KK  E+
Sbjct:    5 KQRKKRKPYTRYQTMVLENEFINNSYITRQKRWEISCKLHLSERQVKVWFQNRRMKRKKLNER 67

[Close]

BLAST of HoxC12-like protein vs. TrEMBL
Match: A0A4D6QJT8 (Post2 OS=Acanthochitona rubrolineata OX=761904 PE=2 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 9.712e-23
Identity = 44/74 (59.46%), Postives = 59/74 (79.73%), Query Frame = 1

Query:  433 NKSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK 654
            N  V+   ++ K R KR+PY+RYQ MVLE+E++N  YI+RQKRW+I+CKL L+ERQ+K+WFQNRRMK KK  E+
Sbjct:  163 NGQVDGGTQEPKGRKKRKPYTRYQTMVLENEFLNNSYITRQKRWEISCKLQLTERQVKVWFQNRRMKRKKLNER 236

[Close]

BLAST of HoxC12-like protein vs. Ensembl Cavefish
Match: hoxc12a (homeobox protein Hox-C12a-like [Source:NCBI gene;Acc:103031159])

HSP 1 Score: 76.2554 bits (186), Expect = 7.246e-16
Identity = 32/59 (54.24%), Postives = 48/59 (81.36%), Query Frame = 1

Query:  466 KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            + R KR+PYS+ QL  LE E++  E+I+RQ+R +++ +LNLS++Q+KIWFQNRRMK K+
Sbjct:  208 RTRKKRKPYSKLQLAELEGEFMMNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 266

[Close]

BLAST of HoxC12-like protein vs. Ensembl Cavefish
Match: hoxd9a (homeobox protein Hox-D9a [Source:NCBI gene;Acc:103033248])

HSP 1 Score: 74.7146 bits (182), Expect = 2.102e-15
Identity = 34/62 (54.84%), Postives = 49/62 (79.03%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK 654
            R KR PY++YQ + LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK N+E+
Sbjct:  196 RKKRCPYTKYQTLELEKEFLYNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMNRER 257

[Close]

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK-NKEK 654
            R KR PY++YQ + LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK N+E+
Sbjct:  196 RKKRCPYTKYQTLELEKEFLYNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMNRER 257

[Close]

BLAST of HoxC12-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000005320.2 (homeobox protein Hox-A9a-like [Source:NCBI gene;Acc:103022020])

HSP 1 Score: 73.9442 bits (180), Expect = 3.562e-15
Identity = 31/57 (54.39%), Postives = 46/57 (80.70%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR PY+++Q++ LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK
Sbjct:  192 RKKRCPYTKHQILELEKEFLFNTYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKK 248

[Close]

BLAST of HoxC12-like protein vs. Ensembl Cavefish
Match: hoxd12a (homeobox protein Hox-D12a-like [Source:NCBI gene;Acc:103047027])

HSP 1 Score: 73.559 bits (179), Expect = 4.620e-15
Identity = 32/59 (54.24%), Postives = 49/59 (83.05%), Query Frame = 1

Query:  466 KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            + R KR+PY++ QL  LE+E++  E+I+RQKR +++ +LNLS++Q+KIWFQNRRMK K+
Sbjct:  192 RARKKRKPYTKPQLAELENEFMINEFINRQKRKELSDRLNLSDQQVKIWFQNRRMKKKR 250

[Close]

BLAST of HoxC12-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011221.1 (pep scaffold:Pmarinus_7.0:GL477881:55654:55833:1 gene:ENSPMAG00000010194.1 transcript:ENSPMAT00000011221.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 67.0106 bits (162), Expect = 3.648e-15
Identity = 30/57 (52.63%), Postives = 45/57 (78.95%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR PY++YQ + LE E++   Y++R++R +I+  +NL++RQ+KIWFQNRRMK KK
Sbjct:    2 RKKRCPYTKYQTLELEKEFLFNMYLTRERRLEISRGVNLTDRQVKIWFQNRRMKLKK 58

[Close]

BLAST of HoxC12-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011242.1 (pep scaffold:Pmarinus_7.0:GL476758:607601:607780:-1 gene:ENSPMAG00000010215.1 transcript:ENSPMAT00000011242.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.855 bits (159), Expect = 9.998e-15
Identity = 33/59 (55.93%), Postives = 45/59 (76.27%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNK 648
            R KR PYS+ Q + LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK K
Sbjct:    2 RKKRCPYSKQQTLELEKEFLFNMYLTRDRRYEVARGLNLTERQVKIWFQNRRMKLKKMK 60

[Close]

BLAST of HoxC12-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011060.1 (pep scaffold:Pmarinus_7.0:GL482503:5543:5722:1 gene:ENSPMAG00000010033.1 transcript:ENSPMAT00000011060.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.855 bits (159), Expect = 9.998e-15
Identity = 33/59 (55.93%), Postives = 45/59 (76.27%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNK 648
            R KR PYS+ Q + LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK K
Sbjct:    2 RKKRCPYSKQQTLELEKEFLFNMYLTRDRRYEVARGLNLTERQVKIWFQNRRMKLKKMK 60

[Close]

BLAST of HoxC12-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005057.1 (pep scaffold:Pmarinus_7.0:GL483321:9136:13526:-1 gene:ENSPMAG00000004598.1 transcript:ENSPMAT00000005057.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.4698 bits (158), Expect = 3.111e-14
Identity = 32/65 (49.23%), Postives = 45/65 (69.23%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK*TLP 666
            R  R+ YSRYQ + LE E++   Y++R++R +++  L LSERQ+KIWFQNRRMK KK   +   P
Sbjct:   28 RRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHVLGLSERQVKIWFQNRRMKWKKENNRDKFP 92

[Close]

BLAST of HoxC12-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011449.1 (pep scaffold:Pmarinus_7.0:GL493006:3300:3479:1 gene:ENSPMAG00000010422.1 transcript:ENSPMAT00000011449.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.3142 bits (155), Expect = 4.250e-14
Identity = 29/57 (50.88%), Postives = 46/57 (80.70%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR PY+++Q + LE E++ + Y++R++R +I+  L+L++RQ+KIWFQNRRMK KK
Sbjct:    2 RKKRCPYTKHQTLELEKEFLFSMYLTRERRLEISHLLSLTDRQVKIWFQNRRMKLKK 58

[Close]

BLAST of HoxC12-like protein vs. Ensembl Yeast
Match: YOX1 (Homeobox transcriptional repressor; binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; phosphorylated by Cdc28p; relocalizes from nucleus to cytoplasm upon DNA replication stress; YOX1 has a paralog, YHP1, that arose from the whole genome duplication [Source:SGD;Acc:S000004489])

HSP 1 Score: 44.669 bits (104), Expect = 7.029e-6
Identity = 20/59 (33.90%), Postives = 38/59 (64.41%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNK 648
            R KRR  S  +L +L++E+      S++KR ++A   +++E+ ++IWFQN+R   K+ +
Sbjct:  177 RRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKRQR 235

[Close]

BLAST of HoxC12-like protein vs. Ensembl Nematostella
Match: MOXC (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR27])

HSP 1 Score: 67.3958 bits (163), Expect = 1.148e-14
Identity = 31/72 (43.06%), Postives = 49/72 (68.06%), Query Frame = 1

Query:  433 NKSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNK 648
            N+    E+   ++R +R  +S+YQL  LE E+    Y++R +R++IA  L+L ERQ+K+WFQNRRMK K+ +
Sbjct:    2 NEMERNEDAKSRKRKERTVFSKYQLTELEREFCRNNYLTRLRRYEIAVSLDLGERQVKVWFQNRRMKWKRGR 73

[Close]

BLAST of HoxC12-like protein vs. Ensembl Nematostella
Match: MOXB (MoxB; Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR28])

HSP 1 Score: 65.0846 bits (157), Expect = 1.190e-13
Identity = 29/63 (46.03%), Postives = 48/63 (76.19%), Query Frame = 1

Query:  466 KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK 654
            K+R +R  ++++Q+  LE+E+    Y++R +R++IA  L+L+ERQ+K+WFQNRRMK K+ K K
Sbjct:   15 KKRKERTAFTKHQIQELENEFQRNNYLTRLRRYEIAVSLDLTERQVKVWFQNRRMKWKRVKGK 77

[Close]

BLAST of HoxC12-like protein vs. Ensembl Nematostella
Match: ANTHOX1A.NV (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGM8])

HSP 1 Score: 65.0846 bits (157), Expect = 3.218e-13
Identity = 30/56 (53.57%), Postives = 44/56 (78.57%), Query Frame = 1

Query:  478 KRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKN 645
            KR  Y+R QL+ LE E+  T Y+++++R ++A  L+L+ERQ+KIWFQNRRMK KK+
Sbjct:   82 KRMAYTRIQLLELEKEFHFTRYLTKERRTEMARMLDLTERQVKIWFQNRRMKWKKD 137

[Close]

BLAST of HoxC12-like protein vs. Ensembl Nematostella
Match: EDO33847 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR26])

HSP 1 Score: 61.2326 bits (147), Expect = 1.015e-12
Identity = 27/50 (54.00%), Postives = 40/50 (80.00%), Query Frame = 1

Query:  499 YQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNK 648
            +QL  LE+E+I   Y++R +R++IA  L+L+ERQ+K+WFQNRRMK K+ K
Sbjct:    1 HQLQELENEFIRNNYLTRLRRYEIAVSLDLTERQVKVWFQNRRMKWKRVK 50

[Close]

BLAST of HoxC12-like protein vs. Ensembl Nematostella
Match: HOX2 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RS10])

HSP 1 Score: 63.929 bits (154), Expect = 2.284e-12
Identity = 30/57 (52.63%), Postives = 41/57 (71.93%), Query Frame = 1

Query:  481 RRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKE 651
            R  Y+  QL+ LE E+    Y+SR +R  IA  L+LSE+Q+KIWFQNRR+K KK+K+
Sbjct:  127 RTAYTSMQLLELEKEFSQNRYLSRLRRIQIAALLDLSEKQVKIWFQNRRVKWKKDKK 183

[Close]

BLAST of HoxC12-like protein vs. Ensembl Medaka
Match: hoxc12a (homeobox protein Hox-C12a [Source:NCBI gene;Acc:101173058])

HSP 1 Score: 75.485 bits (184), Expect = 1.192e-15
Identity = 32/59 (54.24%), Postives = 48/59 (81.36%), Query Frame = 1

Query:  466 KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            + R KR+PYS+ QL  LE E++  E+I+RQ+R +++ +LNLS++Q+KIWFQNRRMK K+
Sbjct:  203 RTRKKRKPYSKLQLAELEGEFMLNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 261

[Close]

BLAST of HoxC12-like protein vs. Ensembl Medaka
Match: hoxa9 (homeobox A9 [Source:NCBI gene;Acc:100049208])

HSP 1 Score: 74.3294 bits (181), Expect = 2.353e-15
Identity = 31/57 (54.39%), Postives = 46/57 (80.70%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR PY+++Q++ LE E++   Y++R +R+++A  LNL+ERQ+KIWFQNRRMK KK
Sbjct:  197 RKKRCPYTKHQILELEKEFLFNTYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKK 253

[Close]

BLAST of HoxC12-like protein vs. Ensembl Medaka
Match: hoxd12a (homeobox D12 [Source:NCBI gene;Acc:101162794])

HSP 1 Score: 74.3294 bits (181), Expect = 2.542e-15
Identity = 33/59 (55.93%), Postives = 49/59 (83.05%), Query Frame = 1

Query:  466 KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            + R KR+PYS+ QL  LE+E++  E+I+RQKR +++ KL+LS++Q+KIWFQNRRMK K+
Sbjct:  186 RSRKKRKPYSKPQLAELENEFLMNEFINRQKRKELSDKLDLSDQQVKIWFQNRRMKKKR 244

[Close]

BLAST of HoxC12-like protein vs. Ensembl Medaka
Match: hoxa11b (homeobox protein Hox-A11b [Source:NCBI gene;Acc:101158794])

HSP 1 Score: 74.3294 bits (181), Expect = 3.194e-15
Identity = 43/115 (37.39%), Postives = 62/115 (53.91%), Query Frame = 1

Query:  316 FHSSFNHLSFRYPQAIQPVSLSSADKFVSENLPSSCPNSNKSVEKEEKDQ------KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            F  ++       P+A +    S A      +   SC   + S   EEK        + R KR PYS+YQ+  LE E+  + YI+++KR  ++  LNL++RQ+KIWFQNRRMK KK
Sbjct:  138 FDPAYGSAEGSVPEADRHSRTSPAPAHAGSDSAESCSPKSSSGNSEEKQTSSGSVPRTRKKRCPYSKYQIRELEREFFFSVYINKEKRMQLSRMLNLTDRQVKIWFQNRRMKEKK 252

[Close]

BLAST of HoxC12-like protein vs. Ensembl Medaka
Match: hoxb9a (homeobox B9 [Source:NCBI gene;Acc:100049206])

HSP 1 Score: 73.9442 bits (180), Expect = 5.280e-15
Identity = 32/57 (56.14%), Postives = 44/57 (77.19%), Query Frame = 1

Query:  472 RTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            R KR PY++YQ + LE E++   Y++R +R ++A  LNL+ERQ+KIWFQNRRMK KK
Sbjct:  218 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARALNLTERQVKIWFQNRRMKMKK 274

[Close]

BLAST of HoxC12-like protein vs. Planmine SMEST
Match: SMESG000022668.1 (SMESG000022668.1)

HSP 1 Score: 330.872 bits (847), Expect = 1.989e-116
Identity = 160/163 (98.16%), Postives = 161/163 (98.77%), Query Frame = 1

Query:  166 MIHDNDNYIYHHNWAPESPIYTPQYEWHPLGPIKESISGFPDYIPHVKESFHSSFNHLSFRYPQAIQPVSLSSADKFVSENLPSSCPNSNKSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK 654
            MIHDNDNYIYHHNWAPESPIYTPQYEWHPLGPIKESISGFPDYIPHVKESFH SFN+LSFRYPQAIQPVSLSSADKF SENLPSSCPNSNKSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK
Sbjct:    1 MIHDNDNYIYHHNWAPESPIYTPQYEWHPLGPIKESISGFPDYIPHVKESFHPSFNNLSFRYPQAIQPVSLSSADKFASENLPSSCPNSNKSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK 163

[Close]

BLAST of HoxC12-like protein vs. Planmine SMEST
Match: SMESG000033048.1 (SMESG000033048.1)

HSP 1 Score: 99.7525 bits (247), Expect = 7.300e-24
Identity = 42/63 (66.67%), Postives = 53/63 (84.13%), Query Frame = 1

Query:  454 EKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKK 642
            E + + R KR+PY+RYQ MVLESE+    YI+RQKRW+I+CKL+LSERQ+K+WFQNRRMK KK
Sbjct:  321 EAEMRSRKKRKPYTRYQTMVLESEFTGNAYITRQKRWEISCKLHLSERQVKVWFQNRRMKKKK 383

[Close]

BLAST of HoxC12-like protein vs. Planmine SMEST
Match: SMESG000054107.1 (SMESG000054107.1)

HSP 1 Score: 93.5893 bits (231), Expect = 4.110e-22
Identity = 44/70 (62.86%), Postives = 57/70 (81.43%), Query Frame = 1

Query:  430 SNKSVEKE---EKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRM 630
            +N  +E+E   E D + R KR+PY+RYQ +VLESE+ +  YI+RQKRW+I+CKLNLSERQIK+WFQNRRM
Sbjct:  225 NNPMMEQEYVPEMDHRCRKKRKPYTRYQNLVLESEFNSNSYITRQKRWEISCKLNLSERQIKVWFQNRRM 294

[Close]

BLAST of HoxC12-like protein vs. Planmine SMEST
Match: SMESG000025656.1 (SMESG000025656.1)

HSP 1 Score: 72.7886 bits (177), Expect = 1.330e-14
Identity = 35/77 (45.45%), Postives = 52/77 (67.53%), Query Frame = 1

Query:  481 RRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKNKEK*TLPRILCR*LPITANPII 711
            R  +S+ QL+ LE E+I+T Y+ R  R  +A KLNL E+QIK+WFQNRRMK K+++ +    + L   LP ++N I+
Sbjct:   97 RTTFSQSQLLELEKEFIHTAYLDRANRISLAGKLNLKEKQIKVWFQNRRMKRKRDESEQKRRKSLNENLPDSSNTIV 173

[Close]

BLAST of HoxC12-like protein vs. Planmine SMEST
Match: SMESG000044469.1 (SMESG000044469.1)

HSP 1 Score: 68.5514 bits (166), Expect = 4.982e-14
Identity = 34/72 (47.22%), Postives = 50/72 (69.44%), Query Frame = 1

Query:  430 SNKSVEKEEKDQKERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWFQNRRMKHKKN 645
            SN    K ++  + +  R+ YSR Q + LE E+   +Y++R++R +IA  + LSERQIKIWFQNRRMK+KK+
Sbjct:   92 SNTRKNKSDRSAEYKRSRQAYSRQQTLELEKEFYYNQYLTRRRRIEIANSVCLSERQIKIWFQNRRMKYKKD 163

The following BLAST results are available for this feature:

BLAST of HoxC12-like protein vs. Ensembl Human
BLAST of HoxC12-like protein vs. Ensembl Celegans
BLAST of HoxC12-like protein vs. Ensembl Fly
BLAST of HoxC12-like protein vs. Ensembl Zebrafish
BLAST of HoxC12-like protein vs. Ensembl Xenopus
BLAST of HoxC12-like protein vs. Ensembl Mouse
BLAST of HoxC12-like protein vs. UniProt/SwissProt
BLAST of HoxC12-like protein vs. TrEMBL
BLAST of HoxC12-like protein vs. Ensembl Cavefish
BLAST of HoxC12-like protein vs. Ensembl Sea Lamprey
BLAST of HoxC12-like protein vs. Ensembl Yeast
BLAST of HoxC12-like protein vs. Ensembl Nematostella
BLAST of HoxC12-like protein vs. Ensembl Medaka
BLAST of HoxC12-like protein vs. Planmine SMEST

BLAST of HoxC12-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
HOXC12	6.026e-16	52.46	homeobox C12 [Source:HGNC Symbol;Acc:HGNC:5124]	[more]
HOXD12	3.492e-15	52.54	homeobox D12 [Source:HGNC Symbol;Acc:HGNC:5135]	[more]
HOXB9	4.243e-15	58.06	homeobox B9 [Source:HGNC Symbol;Acc:HGNC:5120]	[more]
AC004080.3	1.053e-14	53.23	HOXA10-HOXA9 readthrough	[more]
HOXA9	1.401e-14	53.23	homeobox A9 [Source:HGNC Symbol;Acc:HGNC:5109]	[more]

BLAST of HoxC12-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
php-3	3.874e-18	44.94	Posterior Hox gene Paralog [Source:UniProtKB/TrEM...	[more]
php-3	3.874e-18	44.94	Posterior Hox gene Paralog [Source:UniProtKB/TrEM...	[more]
lin-39	5.031e-15	45.68	Homeobox protein lin-39 [Source:UniProtKB/Swiss-P...	[more]
lin-39	5.031e-15	45.68	Homeobox protein lin-39 [Source:UniProtKB/Swiss-P...	[more]
mab-5	5.684e-13	50.00	Homeobox protein mab-5 [Source:UniProtKB/Swiss-Pr...	[more]

BLAST of HoxC12-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Abd-B	1.800e-17	59.65	gene:FBgn0000015 transcript:FBtr0346764	[more]
Abd-B	1.964e-17	59.65	gene:FBgn0000015 transcript:FBtr0083381	[more]
Abd-B	1.964e-17	59.65	gene:FBgn0000015 transcript:FBtr0083382	[more]
Abd-B	1.964e-17	59.65	gene:FBgn0000015 transcript:FBtr0415465	[more]
Abd-B	1.964e-17	59.65	gene:FBgn0000015 transcript:FBtr0083385	[more]

BLAST of HoxC12-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hoxd9a	1.401e-16	42.59	homeobox D9a [Source:NCBI gene;Acc:30350]	[more]
hoxc12a	1.524e-15	54.24	homeobox C12a [Source:ZFIN;Acc:ZDB-GENE-000822-6]	[more]
hoxc12b	2.588e-15	53.33	homeobox C12b [Source:NCBI gene;Acc:58062]	[more]
hoxa9a	3.042e-15	54.39	homeobox A9a [Source:NCBI gene;Acc:58047]	[more]
hoxa9a	3.042e-15	54.39	homeobox A9a [Source:NCBI gene;Acc:58047]	[more]

BLAST of HoxC12-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
irs1	2.865e-15	43.18	insulin receptor substrate 1 [Source:Xenbase;Acc:X...	[more]
ache	1.025e-14	56.45	acetylcholinesterase (Cartwright blood group) [Sou...	[more]
syt8	1.031e-14	52.54	synaptotagmin 8 [Source:Xenbase;Acc:XB-GENE-978920...	[more]
ENSXETT00000012532.1	1.838e-14	53.23	pep primary_assembly:Xenopus_tropicalis_v9.1:6:329...	[more]
hoxc8	2.213e-14	50.77	homeobox C8 [Source:NCBI gene;Acc:448482]	[more]

BLAST of HoxC12-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Hoxc12	6.372e-16	54.24	homeobox C12 [Source:MGI Symbol;Acc:MGI:96194]	[more]
Hoxb9	2.637e-15	58.06	homeobox B9 [Source:MGI Symbol;Acc:MGI:96190]	[more]
Hoxd12	2.740e-15	52.54	homeobox D12 [Source:MGI Symbol;Acc:MGI:96204]	[more]
Hoxa9	1.421e-14	53.23	homeobox A9 [Source:MGI Symbol;Acc:MGI:96180]	[more]
Hoxc8	1.444e-14	50.77	homeobox C8 [Source:MGI Symbol;Acc:MGI:96198]	[more]

BLAST of HoxC12-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P09087\|ABDB_DROME	3.104e-16	59.65	Homeobox protein abdominal-B OS=Drosophila melanog...	[more]
sp\|Q9PWM6\|HXD9A_DANRE	1.058e-15	42.59	Homeobox protein Hox-D9a OS=Danio rerio OX=7955 GN...	[more]
sp\|P31275\|HXC12_HUMAN	2.894e-15	52.46	Homeobox protein Hox-C12 OS=Homo sapiens OX=9606 G...	[more]
sp\|Q8K5B8\|HXC12_MOUSE	4.457e-15	54.24	Homeobox protein Hox-C12 OS=Mus musculus OX=10090 ...	[more]
sp\|P48590\|FTZ_DROHY	4.848e-15	57.75	Segmentation protein fushi tarazu OS=Drosophila hy...	[more]

BLAST of HoxC12-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A165FWV6	2.620e-115	100.00	HoxC12-like protein OS=Schmidtea mediterranea OX=7...	[more]
Q9BLF9	7.549e-26	52.88	Hox class homeodomain protein DjAbd-Ba OS=Dugesia ...	[more]
B6RFY1	3.352e-25	44.52	Post2 hox protein OS=Capitella teleta OX=283909 PE...	[more]
R7UM68	9.468e-23	69.84	Post2 hox protein (Fragment) OS=Capitella teleta O...	[more]
A0A4D6QJT8	9.712e-23	59.46	Post2 OS=Acanthochitona rubrolineata OX=761904 PE=...	[more]

BLAST of HoxC12-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hoxc12a	7.246e-16	54.24	homeobox protein Hox-C12a-like [Source:NCBI gene;A...	[more]
hoxd9a	2.102e-15	54.84	homeobox protein Hox-D9a [Source:NCBI gene;Acc:103...	[more]
hoxd9a	2.102e-15	54.84	homeobox protein Hox-D9a [Source:NCBI gene;Acc:103...	[more]
ENSAMXT00000005320.2	3.562e-15	54.39	homeobox protein Hox-A9a-like [Source:NCBI gene;Ac...	[more]
hoxd12a	4.620e-15	54.24	homeobox protein Hox-D12a-like [Source:NCBI gene;A...	[more]

BLAST of HoxC12-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000011221.1	3.648e-15	52.63	pep scaffold:Pmarinus_7.0:GL477881:55654:55833:1 g...	[more]
ENSPMAT00000011242.1	9.998e-15	55.93	pep scaffold:Pmarinus_7.0:GL476758:607601:607780:-...	[more]
ENSPMAT00000011060.1	9.998e-15	55.93	pep scaffold:Pmarinus_7.0:GL482503:5543:5722:1 gen...	[more]
ENSPMAT00000005057.1	3.111e-14	49.23	pep scaffold:Pmarinus_7.0:GL483321:9136:13526:-1 g...	[more]
ENSPMAT00000011449.1	4.250e-14	50.88	pep scaffold:Pmarinus_7.0:GL493006:3300:3479:1 gen...	[more]

BLAST of HoxC12-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
YOX1	7.029e-6	33.90	Homeobox transcriptional repressor; binds to Mcm1p...	[more]

BLAST of HoxC12-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
MOXC	1.148e-14	43.06	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
MOXB	1.190e-13	46.03	MoxB; Predicted protein [Source:UniProtKB/TrEMBL;...	[more]
ANTHOX1A.NV	3.218e-13	53.57	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33847	1.015e-12	54.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
HOX2	2.284e-12	52.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of HoxC12-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hoxc12a	1.192e-15	54.24	homeobox protein Hox-C12a [Source:NCBI gene;Acc:10...	[more]
hoxa9	2.353e-15	54.39	homeobox A9 [Source:NCBI gene;Acc:100049208]	[more]
hoxd12a	2.542e-15	55.93	homeobox D12 [Source:NCBI gene;Acc:101162794]	[more]
hoxa11b	3.194e-15	37.39	homeobox protein Hox-A11b [Source:NCBI gene;Acc:10...	[more]
hoxb9a	5.280e-15	56.14	homeobox B9 [Source:NCBI gene;Acc:100049206]	[more]

BLAST of HoxC12-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000022668.1	1.989e-116	98.16	SMESG000022668.1	[more]
SMESG000033048.1	7.300e-24	66.67	SMESG000033048.1	[more]
SMESG000054107.1	4.110e-22	62.86	SMESG000054107.1	[more]
SMESG000025656.1	1.330e-14	45.45	SMESG000025656.1	[more]
SMESG000044469.1	4.982e-14	47.22	SMESG000044469.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30000303 ID=SMED30000303|Name=HoxC12-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=806bp
TATATTCCACAACTGTGCAGTTTGCGATCTGTATTGCAATAGATATTGGA
ATCGACTGACGGAAGTACTCCATTCTTTCTCGCTGCAACTGGATTTTGAA
GCTGTGGAGCATTTCAGTTTTGAGCATCGATTGGAAGCTGGAAAACTAAA
AAAAGGTTCACTATTATGATTCATGATAACGACAACTACATTTACCATCA
TAATTGGGCCCCCGAATCACCGATTTACACTCCCCAGTACGAATGGCATC
CTCTGGGTCCAATCAAAGAATCTATCAGCGGGTTCCCAGACTACATCCCA
CATGTCAAGGAATCCTTCCATTCGTCATTCAATCATCTGTCATTCAGATA
TCCCCAAGCAATCCAACCGGTTAGTTTAAGTTCTGCTGACAAATTCGTAA
GTGAAAATTTACCGAGTTCTTGTCCGAATTCAAATAAATCAGTTGAAAAA
GAAGAGAAAGACCAAAAGGAAAGGACAAAACGACGTCCATACTCTCGATA
TCAGCTGATGGTGCTGGAAAGCGAATATATCAACACTGAATATATATCCA
GACAGAAACGGTGGGACATCGCCTGCAAGTTGAATTTATCAGAGCGCCAA
ATCAAAATATGGTTCCAGAATCGCCGGATGAAACATAAAAAGAATAAAGA
GAAATAAACCCTTCCTAGGATTTTGTGTCGATGATTGCCAATTACAGCAA
ACCCAATAATAAAATTCCTTTACTCCAAAAATATCAGTATATTATCAAGT
GCTGTGTGAATGTAATAAATAAATAAAAATAAATATTAACTAATTTTTTC
AGTGAC

protein sequence of SMED30000303-orf-1

>SMED30000303-orf-1 ID=SMED30000303-orf-1|Name=SMED30000303-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=164bp
MIHDNDNYIYHHNWAPESPIYTPQYEWHPLGPIKESISGFPDYIPHVKES
FHSSFNHLSFRYPQAIQPVSLSSADKFVSENLPSSCPNSNKSVEKEEKDQ
KERTKRRPYSRYQLMVLESEYINTEYISRQKRWDIACKLNLSERQIKIWF
QNRRMKHKKNKEK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000028	Category 2 cell
PLANA:0000034	epidermis
PLANA:0000035	Category 3 cell
PLANA:0000101	muscle cell
PLANA:0000142	posterior region of the whole animal
PLANA:0000421	tail
PLANA:0000429	neoblast
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR020479	Homeobox_metazoa
IPR001356	Homeobox_dom
IPR009057	Homeobox-like_sf
IPR017970	Homeobox_CS

Vocabulary: **molecular function**
Term	Definition
GO:0003677	DNA binding
GO:0043565	sequence-specific DNA binding

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR020479	Homeobox domain, metazoa	PRINTS	PR00024	HOMEOBOX	coord: 149..158 score: 80.31 coord: 139..149 score: 63.83 coord: 124..135 score: 27.77
IPR001356	Homeobox domain	SMART	SM00389	HOX_1	coord: 102..163 e-value: 8.0E-18 score: 75.2
IPR001356	Homeobox domain	PFAM	PF00046	Homeodomain	coord: 103..159 e-value: 4.8E-20 score: 71.2
IPR001356	Homeobox domain	PROSITE	PS50071	HOMEOBOX_2	coord: 100..160 score: 19.24
IPR001356	Homeobox domain	CDD	cd00086	homeodomain	coord: 103..161 e-value: 3.50895E-19 score: 74.202
None	No IPR available	GENE3D	G3DSA:1.10.10.60		coord: 90..163 e-value: 8.0E-24 score: 85.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 91..107
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 79..107
None	No IPR available	PANTHER	PTHR45874	FAMILY NOT NAMED	coord: 62..162
None	No IPR available	PANTHER	PTHR45874:SF4	HOMEOBOX PROTEIN ABDOMINAL-B	coord: 62..162
IPR017970	Homeobox, conserved site	PROSITE	PS00027	HOMEOBOX_1	coord: 135..158
IPR009057	Homeobox-like domain superfamily	SUPERFAMILY	SSF46689	Homeodomain-like	coord: 84..161