tRNA-dihydrouridine synthase

Overview
NametRNA-dihydrouridine synthase
Smed IDSMED30000267
Length (bp)1267
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of tRNA-dihydrouridine synthase (SMED30000267) t-SNE clustered cells

Violin plots show distribution of expression levels for tRNA-dihydrouridine synthase (SMED30000267) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of tRNA-dihydrouridine synthase (SMED30000267) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for tRNA-dihydrouridine synthase (SMED30000267) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30000267

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30000267h1SMcG0010494 dd_Smed_v4_9471_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30000267h1SMcG0010494 dd_Smed_v4_9471_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Human
Match: DUS4L (dihydrouridine synthase 4 like [Source:HGNC Symbol;Acc:HGNC:21517])

HSP 1 Score: 233.032 bits (593), Expect = 4.901e-73
Identity = 116/289 (40.14%), Postives = 184/289 (63.67%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLIN 1047
            + + +L FR LVR+  CDL YTPMI+A  F+KS KAR SEF++   D PLIVQFA+ +   L +A+++V   A+G+D+NCGCPQ+WA+ E  G  L+ +PEL+ +M+K V+       N++ + GFSVS KIRI + +     TV+L ++ +  GV W+TVH RTA ER +P  +  +  I    N+S  ++ NGDI SL++A   +++T   GVM ARG+LANPA+F+      +   C   ++D+ ++ G      HQHL +M+E   +R ++ + +++SS++ +I+
Sbjct:   35 VRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVR-------NQVETPGFSVSIKIRIHDDLK---RTVDLCQKAEATGVSWITVHGRTAEERHQPVHYDSIKII--KENMSIPVIANGDIRSLKEAENVWRITGTDGVMVARGLLANPAMFAGYEE--TPLKCIWDWVDIALELGTPYMCFHQHLMYMMEKITSRQEKRVFNALSSTSAIID 309
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Human
Match: DUS4L (dihydrouridine synthase 4 like [Source:HGNC Symbol;Acc:HGNC:21517])

HSP 1 Score: 233.032 bits (593), Expect = 4.901e-73
Identity = 116/289 (40.14%), Postives = 184/289 (63.67%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLIN 1047
            + + +L FR LVR+  CDL YTPMI+A  F+KS KAR SEF++   D PLIVQFA+ +   L +A+++V   A+G+D+NCGCPQ+WA+ E  G  L+ +PEL+ +M+K V+       N++ + GFSVS KIRI + +     TV+L ++ +  GV W+TVH RTA ER +P  +  +  I    N+S  ++ NGDI SL++A   +++T   GVM ARG+LANPA+F+      +   C   ++D+ ++ G      HQHL +M+E   +R ++ + +++SS++ +I+
Sbjct:   35 VRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVR-------NQVETPGFSVSIKIRIHDDLK---RTVDLCQKAEATGVSWITVHGRTAEERHQPVHYDSIKII--KENMSIPVIANGDIRSLKEAENVWRITGTDGVMVARGLLANPAMFAGYEE--TPLKCIWDWVDIALELGTPYMCFHQHLMYMMEKITSRQEKRVFNALSSTSAIID 309
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Human
Match: DUS4L-BCAP29 (DUS4L-BCAP29 readthrough [Source:NCBI gene;Acc:115253422])

HSP 1 Score: 185.267 bits (469), Expect = 7.575e-53
Identity = 93/215 (43.26%), Postives = 139/215 (64.65%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGV 825
            + + +L FR LVR+  CDL YTPMI+A  F+KS KAR SEF++   D PLIVQFA+ +   L +A+++V   A+G+D+NCGCPQ+WA+ E  G  L+ +PEL+ +M+K V+       N++ + GFSVS KIRI + +     TV+L ++ +  GV W+TVH RTA ER +P  +  +  I    N+S  ++ NGDI SL++A   +++T   GV
Sbjct:   35 VRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVR-------NQVETPGFSVSIKIRIHDDLK---RTVDLCQKAEATGVSWITVHGRTAEERHQPVHYDSIKII--KENMSIPVIANGDIRSLKEAENVWRITGTDGV 237
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Human
Match: DUS4L-BCAP29 (DUS4L-BCAP29 readthrough [Source:NCBI gene;Acc:115253422])

HSP 1 Score: 185.267 bits (469), Expect = 7.575e-53
Identity = 93/215 (43.26%), Postives = 139/215 (64.65%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGV 825
            + + +L FR LVR+  CDL YTPMI+A  F+KS KAR SEF++   D PLIVQFA+ +   L +A+++V   A+G+D+NCGCPQ+WA+ E  G  L+ +PEL+ +M+K V+       N++ + GFSVS KIRI + +     TV+L ++ +  GV W+TVH RTA ER +P  +  +  I    N+S  ++ NGDI SL++A   +++T   GV
Sbjct:   35 VRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVR-------NQVETPGFSVSIKIRIHDDLK---RTVDLCQKAEATGVSWITVHGRTAEERHQPVHYDSIKII--KENMSIPVIANGDIRSLKEAENVWRITGTDGV 237
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Human
Match: DUS4L-BCAP29 (DUS4L-BCAP29 readthrough [Source:NCBI gene;Acc:115253422])

HSP 1 Score: 185.267 bits (469), Expect = 7.575e-53
Identity = 93/215 (43.26%), Postives = 139/215 (64.65%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGV 825
            + + +L FR LVR+  CDL YTPMI+A  F+KS KAR SEF++   D PLIVQFA+ +   L +A+++V   A+G+D+NCGCPQ+WA+ E  G  L+ +PEL+ +M+K V+       N++ + GFSVS KIRI + +     TV+L ++ +  GV W+TVH RTA ER +P  +  +  I    N+S  ++ NGDI SL++A   +++T   GV
Sbjct:   35 VRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVR-------NQVETPGFSVSIKIRIHDDLK---RTVDLCQKAEATGVSWITVHGRTAEERHQPVHYDSIKII--KENMSIPVIANGDIRSLKEAENVWRITGTDGV 237
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Celegans
Match: C45G9.2 (Uncharacterized tRNA-dihydrouridine synthase-like protein C45G9.2 [Source:UniProtKB/Swiss-Prot;Acc:Q09504])

HSP 1 Score: 192.586 bits (488), Expect = 2.611e-58
Identity = 109/294 (37.07%), Postives = 167/294 (56.80%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRL 1062
            + + +L FR LVR    D+ +TPMI A +F++SEK R SE S C  D PLIVQFA+ +P  L EA+++VY+ + GVDLNCGCP+     +  G +L+ +PEL+++M++  +  +PD         FSVS KIRI   I    +TV+L R+ +  GV  +TVH RT  +R+EP   + L   +   +VS  ++ NG I + ++A    + T   G+M+A G+L NPALF+      S  DC   F+ L  +YG      HQHL +ML    +   R + + ++    + + +N L
Sbjct:    2 VRYSKLAFRQLVRVYDVDVCFTPMIYAKNFIESEKCRSSELSVCEGDSPLIVQFATDDPFVLSEAAEMVYKCSTGVDLNCGCPKHDVRSKGFGSALLSKPELLADMVRQTRARIPD-------PDFSVSLKIRINHDIE---KTVDLCRKAEAAGVTHLTVHGRTPSQRAEPIDIQALR--IVKDSVSVPIIANGGITTREEALFLAEQTGVDGIMAANGLLDNPALFAGHEHTPS--DCVENFMRLSREYGLDWLLYHQHLQYMLRPVFSAQQRRVFNELNGRLAIDHFLNNL 281
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Celegans
Match: F36A2.2 (pep chromosome:WBcel235:I:8801612:8804697:-1 gene:WBGene00009452.1 transcript:F36A2.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F36A2.2)

HSP 1 Score: 132.109 bits (331), Expect = 1.373e-33
Identity = 94/318 (29.56%), Postives = 148/318 (46.54%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEP---ARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYW-----MLEGDLNRSDRTLLHSMSSSAGLINIVNRLSSWKLSAS*INDDVQVLNRIL 1125
            L FRM  R+ G  L +TPMI A  F+     R +  +   +DRPL+VQF +   +  L A +LV +  DGVDLN GCPQ  A + + G  L  E +LI EM+  V+    D           +S KIR+    +   +TVE  +RL   G   +TVH RT   +      A W ++ ++V A      ++ NG+I    D     Q T    +MSA G+L NP +F   ++ + ++  A  +++   ++    S +  H++      +LE +  R   +L H +       NIV  L+    S +    + +V  R L
Sbjct:   86 LAFRMFTRKYGAQLTFTPMIHAHLFVNDGTYRRNSLALVKADRPLVVQFCANKVDTFLAACRLVEDVCDGVDLNLGCPQMVAKRGRYGSWLQDEVDLICEMVSAVR----DYCR------LPISCKIRV---RDDRQQTVEYAKRLVDAGATMLTVHGRTRDMKGAETGLADWSRIRDVVEAVGSRVPVMANGNIQFPGDVERCMQATGAVAIMSAEGLLYNPLIFDDANAHVDTWKIAAEYLEYAKKFNAGTSAIRAHVFRICHHSLLEYEDLRMRVSLEHRIED---FENIVEELAKRAKSDAEAGKNREVEARTL 387
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Celegans
Match: Y37E11B.5 (tRNA-dihydrouridine(47) synthase [NAD(P)(+)] [Source:UniProtKB/TrEMBL;Acc:Q9TYN2])

HSP 1 Score: 89.7373 bits (221), Expect = 4.885e-19
Identity = 73/258 (28.29%), Postives = 116/258 (44.96%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYES--ADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIR--ICEGINGTAETVELLRRLDRMGVDWVTVHARTAVER-SEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSR----ISS---FDCARMFIDLGIQY 933
            LPFR +  + G D+    M +A S L    + YS       ++   VQ A    + + +AS++V E+   D +D+N GCP     Q+  GC+L   P+ + E++   K         +      ++ KIR  + EG+    E VE +++      D +T H R+  +R +  A W      V  A     L V GDI+S +D  E  +     G+M  RG L  P +F+    R    ISS   FD  + F+D G+ +
Sbjct:  217 LPFRRICVDYGADITCGEMALATSILSGTASEYSLLKRHPCEKIFGVQLAGGFADTMAKASQIVVENFDVDFIDINMGCPIDVVNQKGGGCALPSRPQKLFEVLAATK--------SVLGGCCPLTVKIRTGMKEGVLKAPEYVEHMKKHSWHTPDLITFHPRSKEQRYTRLANW-DFTFPVQEATKPVPLWVCGDILSWEDYYERLEQYPVNGIMIGRGALIKPWIFTEIDERRTWDISSTERFDLLKKFVDYGLDH 465
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Celegans
Match: dus-2 (DihydroUridine Synthase two homolog [Source:UniProtKB/TrEMBL;Acc:Q9XWJ9])

HSP 1 Score: 70.4774 bits (171), Expect = 5.223e-13
Identity = 59/265 (22.26%), Postives = 123/265 (46.42%), Query Frame = 1 
Query:  193 RLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCS----SDRPL----------IVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERS-EPARWKQLGEIVSAANVSCGLVVNG---DIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQY 933
            R P R+L  + G DL YT  I+    +++ +       +       D  L          I+Q  + +  +  + +++V +   G+D+N GCP+ ++I   +G +L+ + E I +++ ++K           +    V+ KIR+   ++   +T++L++ +++  V  + VH R   ER  +  R  ++ ++  A   S  ++ NG   +I    D  +   +T+    M AR  L+ P++F  E   +  ++  R F++L  QY
Sbjct:   19 RTPLRLLCLKYGADLCYTEEIVDKKLIEATRVVNEALGTIDYRNGDDIILRLAPEEKGRCILQIGTNSGEKAAKIAQIVGDDVAGIDVNMGCPKPFSIHCGMGAALLTQTEKIVDILTSLK----------SAAKVPVTCKIRV---LDDPEDTLKLVQEIEKCRVSALGVHGRRRDERQPDKCRIDEIRDVAQAVQ-SIPVISNGLSDEIEQYSDFEKYQLLTETSSTMIARKALSTPSIFRREGC-LDKYEDIRNFLELACQY 268
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Fly
Match: CG10495 (gene:FBgn0032750 transcript:FBtr0081150)

HSP 1 Score: 206.838 bits (525), Expect = 2.582e-62
Identity = 105/300 (35.00%), Postives = 176/300 (58.67%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANV----SCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTE--SSRISSFDCARMFIDLGIQYGCQI--SQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVN 1056
            + + +L FR LVR  G  LA+TPM+I+DS   SEKAR +EFS+ + D+PLI QFA+++P E + +++L+Y   DG+DLNCGCPQ WA+ +  GC ++++PEL+ ++++ V+  +P          FSVS K+R+  G      T++L R+L+  GV ++T+H RT  ++      K   +I + + V       L+VNG++ S +DA +  + T   GVM+ARG+LANPALF++     + +   C + ++D+    G  +     H HL +M    + R  R   +S+ S   +++ + 
Sbjct:   31 VRYSKLEFRRLVRLNGVQLAFTPMMISDSINNSEKARQNEFSTGADDQPLIAQFAAKDPTEFVTSAQLIYPYVDGIDLNCGCPQSWAMAKGYGCGMLRQPELVHQVVQEVRRTLP--------GDFSVSVKMRLLGGEESLQRTIDLARQLESAGVTFLTLHGRTPAQKHS----KDTLDIPAMSQVRQSLQIPLIVNGNVESYRDACDMHEQTGAAGVMAARGLLANPALFNSNYPDGKTTPLSCVQQWLDIASAAGDNLLFQCFHHHLTFMYSAQMKRDLRVQFNSLGSKEQVVDFLK 318
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Fly
Match: CG3645 (gene:FBgn0031238 transcript:FBtr0078140)

HSP 1 Score: 132.494 bits (332), Expect = 9.833e-34
Identity = 87/272 (31.99%), Postives = 136/272 (50.00%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEP----ARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLN 993
            L +RML R  G +L Y+PM  A+ F    K R     +C  DRPLI+QF   +  ++L+A+ L  +  D VD+N GCPQ  A +   G  L  E EL++E++ T+  KL +P            V+ KIRI E +    +T+   + L+  G   +TVH RT  E+  P    A W  +  +    ++   ++ NG+I++L D +     T   GVMSA G L NPA+F   S  +  +  A  +++L   + C  S +  HL+ +    +N
Sbjct:   41 LAWRMLCRRYGAELCYSPMYHANLFATDPKYRKDALQTCPEDRPLIIQFCGNDAQQILDAALLAQDHCDAVDINLGCPQAIAKRGHYGSFLQDEWELLTEIVSTLHAKLAVP------------VTCKIRIFEDLE---KTIRYAKMLEAAGCQLLTVHGRTR-EQKGPLTGVANWNYIKNVRQ--HIKIPMLANGNILALDDVHRCLTETGVDGVMSAEGNLHNPAIFKGVSPPV--WQMAHEYLELVQLHPCPSSFIRGHLFKLFHHIMN 292
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Fly
Match: CG3645 (gene:FBgn0031238 transcript:FBtr0078141)

HSP 1 Score: 132.494 bits (332), Expect = 9.833e-34
Identity = 87/272 (31.99%), Postives = 136/272 (50.00%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEP----ARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLN 993
            L +RML R  G +L Y+PM  A+ F    K R     +C  DRPLI+QF   +  ++L+A+ L  +  D VD+N GCPQ  A +   G  L  E EL++E++ T+  KL +P            V+ KIRI E +    +T+   + L+  G   +TVH RT  E+  P    A W  +  +    ++   ++ NG+I++L D +     T   GVMSA G L NPA+F   S  +  +  A  +++L   + C  S +  HL+ +    +N
Sbjct:   41 LAWRMLCRRYGAELCYSPMYHANLFATDPKYRKDALQTCPEDRPLIIQFCGNDAQQILDAALLAQDHCDAVDINLGCPQAIAKRGHYGSFLQDEWELLTEIVSTLHAKLAVP------------VTCKIRIFEDLE---KTIRYAKMLEAAGCQLLTVHGRTR-EQKGPLTGVANWNYIKNVRQ--HIKIPMLANGNILALDDVHRCLTETGVDGVMSAEGNLHNPAIFKGVSPPV--WQMAHEYLELVQLHPCPSSFIRGHLFKLFHHIMN 292
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Fly
Match: CG3645 (gene:FBgn0031238 transcript:FBtr0336989)

HSP 1 Score: 132.494 bits (332), Expect = 9.833e-34
Identity = 87/272 (31.99%), Postives = 136/272 (50.00%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEP----ARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLN 993
            L +RML R  G +L Y+PM  A+ F    K R     +C  DRPLI+QF   +  ++L+A+ L  +  D VD+N GCPQ  A +   G  L  E EL++E++ T+  KL +P            V+ KIRI E +    +T+   + L+  G   +TVH RT  E+  P    A W  +  +    ++   ++ NG+I++L D +     T   GVMSA G L NPA+F   S  +  +  A  +++L   + C  S +  HL+ +    +N
Sbjct:   41 LAWRMLCRRYGAELCYSPMYHANLFATDPKYRKDALQTCPEDRPLIIQFCGNDAQQILDAALLAQDHCDAVDINLGCPQAIAKRGHYGSFLQDEWELLTEIVSTLHAKLAVP------------VTCKIRIFEDLE---KTIRYAKMLEAAGCQLLTVHGRTR-EQKGPLTGVANWNYIKNVRQ--HIKIPMLANGNILALDDVHRCLTETGVDGVMSAEGNLHNPAIFKGVSPPV--WQMAHEYLELVQLHPCPSSFIRGHLFKLFHHIMN 292
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Fly
Match: CG1434 (gene:FBgn0030554 transcript:FBtr0073903)

HSP 1 Score: 84.3445 bits (207), Expect = 2.631e-17
Identity = 64/261 (24.52%), Postives = 123/261 (47.13%), Query Frame = 1 
Query:  157 NQIYFIYNLNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSE---------------FSSCSSDRP-LIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSE-PARWKQLGEIVSAANVSCGLVVNGDIMSLQ--DANEAFQVTQC--QGVMSARGILANPALFSTES 876
            N++     +    LP R+L  E+G D+ YT  ++    +KS +                    F +C+ +   L++Q  + +    L   KL+     G+D+N GCP++++I+  +G +L+ +P+  + +++T+  G+             V+ KIRI   + G   T++L+++L   G+  + +HART  ER + PA  + L  +  A ++   ++ NG   ++   D    FQ+ +C    VM AR    N ++F  E 
Sbjct:   24 NKLILAPMVRVGTLPMRLLALEMGADIVYTEELVDIKLIKSIRRPNPALGTVDFVDPSDGTIVFRTCAQETSRLVLQMGTSDAGRALAVGKLLQRDISGLDINMGCPKEFSIKGGMGAALLADPDKAAHILRTLCSGL----------DIPVTCKIRILPDVEG---TIDLVQKLAATGIAAIGIHARTRDERPQHPAHPEVLRAVAQAVDIP--IIANGGSKNMHCYDDLRKFQM-ECGADSVMVARAAQINVSIFRPEG 268
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Zebrafish
Match: dus4l (dihydrouridine synthase 4-like (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-040801-233])

HSP 1 Score: 230.335 bits (586), Expect = 2.348e-72
Identity = 113/292 (38.70%), Postives = 188/292 (64.38%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVN 1056
            + + +L FR LVR+  CD+ +TPMIIA  F++S KAR SEF++  +DRPLIVQFA+++   L +A+ +V   +DGVDLNCGCPQ+WA+ E  G  L+ +PEL+ +M++ V+       N+I +  ++VS KIRI + +    +TV+L ++++  GV ++TVH RTA+ER +P  +  +  I  +  +S  ++ NGDI S+QD     ++T   GVMSARG+L+NPA+FS      +   C   ++D+  ++G   +  H HL  MLE   ++ +R + +++SS++ +I+ ++
Sbjct:   24 VRYSKLAFRTLVRKYDCDVCFTPMIIAADFMRSAKARDSEFTTNKNDRPLIVQFAAKDAQTLADAACVVSPFSDGVDLNCGCPQRWAMSEGYGACLINKPELVKDMVRHVR-------NQIDNPNYAVSIKIRIHKDVR---QTVDLCQKVEAAGVSYITVHGRTAIERHQPVHYDTIKTIKDS--LSIPVIANGDIKSMQDVEAVCELTGVDGVMSARGLLSNPAMFSGFEE--TPLQCVWDWVDIAAEHGTPFTCFHHHLIHMLERITSQPERRVFNNLSSTSAVIDFLH 301
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Zebrafish
Match: dus1l (dihydrouridine synthase 1-like (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-030131-1435])

HSP 1 Score: 130.954 bits (328), Expect = 4.788e-33
Identity = 93/302 (30.79%), Postives = 151/302 (50.00%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKAR----YSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVER---SEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYG-CQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNRLS 1065
            L +R+L R  G +L YTPM+ A  F++    R    YSE +    DRPLI QF + +P   ++A+ L  +  D +DLN GCPQ  A +   G  L  E +L+ +MIK    KL +P            ++ KIR+   I    +TV+  + L++ G   +TVH RT  ++   +  A WK +  +  A N+   +  NG+I  L D +   + T  QGVMSA G L NPALF   S  +  ++ A  ++D+  ++  C +S +  H++  W     +++  R  L    +  G++ +  +L 
Sbjct:   47 LAWRLLSRRHGAELCYTPMLHAQVFVRDANYRRENLYSEVNQ--EDRPLITQFCANDPEVFIQAALLAQDYCDAIDLNLGCPQMIAKRGHYGVFLQDEWDLLEKMIKLANEKLSVP------------ITCKIRVFPEIE---KTVKYAKMLEKAGCQLLTVHGRTKDQKGALTGIASWKHIKAVREAVNIP--VFANGNIQHLSDVHHCMEETGVQGVMSAEGNLHNPALFEGRSPPV--WEMAEEYLDIVEKHSPCSLSFVRAHIFKLWHHTLQIHQDLREDLAKAKNVDGIVEVNRQLK 327
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Zebrafish
Match: dus2 (dihydrouridine synthase 2 [Source:ZFIN;Acc:ZDB-GENE-100922-233])

HSP 1 Score: 85.5001 bits (210), Expect = 1.630e-17
Identity = 70/266 (26.32%), Postives = 122/266 (45.86%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYS--------------EFSSCSSDRPLIV-QFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERS-EPARWKQLGEIVSAANVSCGLVVNG---DIMSLQDANEAF-QVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQY 933
            LP R+L  + G D+ Y   +I     + E+                   F +CS +   +V Q  + +P   L  +KLV      VD+N GCP++++ +  +G +L+ +PE I  ++ T+  G+             V+ KIRI   I    +TV L++R+++ GV  + VH R   ER   P     +  +  A +VS  ++ NG   DI+   +  E F + T    VM AR  + NP++F  + + +S     + +I   ++Y
Sbjct:   30 LPMRLLALDYGADIVYCEELIDIKMAQCERVENDVLQTIDFVAPDERVMFRTCSKESGRVVFQMGTADPERALAVAKLVENDVAAVDVNMGCPKEYSTKGGMGSALLSDPEKIEAILTTLVKGISK----------PVTCKIRILSTIE---DTVNLVKRIEKTGVAAIAVHGRMKDERPRHPVHCDYIQAV--AQSVSVPVIANGGSSDIVKEFEDIETFRESTGASSVMLARAAMWNPSVFRQQGA-LSVDQVMQEYITYAVRY 279
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Zebrafish
Match: dus2 (dihydrouridine synthase 2 [Source:ZFIN;Acc:ZDB-GENE-100922-233])

HSP 1 Score: 85.5001 bits (210), Expect = 1.630e-17
Identity = 70/266 (26.32%), Postives = 122/266 (45.86%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYS--------------EFSSCSSDRPLIV-QFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERS-EPARWKQLGEIVSAANVSCGLVVNG---DIMSLQDANEAF-QVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQY 933
            LP R+L  + G D+ Y   +I     + E+                   F +CS +   +V Q  + +P   L  +KLV      VD+N GCP++++ +  +G +L+ +PE I  ++ T+  G+             V+ KIRI   I    +TV L++R+++ GV  + VH R   ER   P     +  +  A +VS  ++ NG   DI+   +  E F + T    VM AR  + NP++F  + + +S     + +I   ++Y
Sbjct:   30 LPMRLLALDYGADIVYCEELIDIKMAQCERVENDVLQTIDFVAPDERVMFRTCSKESGRVVFQMGTADPERALAVAKLVENDVAAVDVNMGCPKEYSTKGGMGSALLSDPEKIEAILTTLVKGISK----------PVTCKIRILSTIE---DTVNLVKRIEKTGVAAIAVHGRMKDERPRHPVHCDYIQAV--AQSVSVPVIANGGSSDIVKEFEDIETFRESTGASSVMLARAAMWNPSVFRQQGA-LSVDQVMQEYITYAVRY 279
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Zebrafish
Match: dus3l (dihydrouridine synthase 3-like (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-040426-1260])

HSP 1 Score: 80.4925 bits (197), Expect = 7.977e-16
Identity = 67/257 (26.07%), Postives = 119/257 (46.30%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYES--ADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETV-ELLRRLDRMGVDWVTVHARTAVER-SEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFS----TESSRISS---FDCARMFIDLGIQY 933
            LPFR + +  G D+    M +  + L+ + + ++     +S+    VQ     P+ +   ++L+ ++   D VD+N GCP     ++  GC LM       ++++    GM  V++        V   ++I  G+   +    +L+  + + GV  +T+H R+  +R ++ A W  +      A     L  NGDI+S +DA +A + T   G+M ARG L  P LF+    T    ISS    D  R F   G+++
Sbjct:  328 LPFRRVCKRFGADITCGEMAMCTNLLQGQASEWALLKRHASEDLFGVQLEGCFPDTMTRCAELLNQNIDVDFVDINSGCPIDLVYKKGGGCGLMTRTSKFEQIVR----GMNSVLD--------VPLTVKIRTGVQQNSNIAHKLIPEMKKWGVSLITLHGRSREQRYTKLADWDYINTCAQLA-APVPLFGNGDILSYEDAMKARE-TGVSGIMVARGALIKPWLFTEIKETRHWDISSTERLDILRDFTHFGLEH 570
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Xenopus
Match: dus4l (dihydrouridine synthase 4-like [Source:NCBI gene;Acc:493309])

HSP 1 Score: 235.728 bits (600), Expect = 3.601e-74
Identity = 118/289 (40.83%), Postives = 183/289 (63.32%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLIN 1047
            + + +L FR LVR+  CDL YTPMIIA  F+KS KAR SEF++   DRPLIVQFA++    L +A+ LV   A G+DLNCGCPQ+WA+ E  G  L+  PEL+S+M+K V+       N++   GF++S KIRI   I   + TV+L R+ +  GV W+TVH RT  ER +P  +  +  I    ++S  +V NGD+ SL++A    ++T   GVM+ARG+LANPA+F+      +   C + +ID+ +++G   + LH HL +M+E   ++ ++ + + +SS++ +++
Sbjct:   32 VRYSKLAFRTLVRKYDCDLCYTPMIIAADFVKSVKARDSEFTTNQGDRPLIVQFAAKEAQVLADAASLVSPFASGIDLNCGCPQRWAMAEGYGACLINNPELVSDMVKQVR-------NQVGDPGFTISIKIRIHADI---SRTVDLCRKAEAAGVSWITVHGRTHDERHQPVHYDAIKSI--KESLSIPVVANGDVKSLKEAENIREITGADGVMAARGLLANPAMFAGYEE--TPLACIQDWIDITLEHGTPFTCLHHHLIYMMERITSKQEKRVFNVLSSTSAVLD 306
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Xenopus
Match: ubash3b (ubiquitin associated and SH3 domain containing B [Source:Xenbase;Acc:XB-GENE-5757837])

HSP 1 Score: 140.584 bits (353), Expect = 9.403e-37
Identity = 99/298 (33.22%), Postives = 151/298 (50.67%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEF--SSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEP----ARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNR 1059
            L +R+L R  G  L YTPM+ A  F++    R        CS DRPLIVQF + +P   ++A+ L  +  D +DLN GCPQ  A +   G  L  E +L+ +M++    KL +P            V+ KIR+   I    +TVE  + L++ G   +TVH RT  E+  P    A W+ +  + +A N+   +  NG+I  L DA    + T  QGVMSA G L NPALF   +  +  ++ A  ++DL  Q+ C +S +  HL+  W     +++  R  L  + +  G++  VNR
Sbjct:   30 LAWRLLSRRHGVQLCYTPMLHAQVFVRDANYRKENLYCEVCSEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQDEWDLLEKMVQLAHQKLSVP------------VTCKIRVFPEIE---KTVEYAKMLEKAGCQLLTVHGRTK-EQKGPLTGIASWEHIKAVRNAVNIP--VFANGNIQYLNDAERCMRETAVQGVMSAEGNLHNPALFEGRNPVV--WEMAEEYLDLVRQFPCSLSFVRAHLFKLWHHTLQVHQELREELAKVKTLEGVM-AVNR 306
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Xenopus
Match: ubash3b (ubiquitin associated and SH3 domain containing B [Source:Xenbase;Acc:XB-GENE-5757837])

HSP 1 Score: 140.584 bits (353), Expect = 1.147e-36
Identity = 99/298 (33.22%), Postives = 151/298 (50.67%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEF--SSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEP----ARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNR 1059
            L +R+L R  G  L YTPM+ A  F++    R        CS DRPLIVQF + +P   ++A+ L  +  D +DLN GCPQ  A +   G  L  E +L+ +M++    KL +P            V+ KIR+   I    +TVE  + L++ G   +TVH RT  E+  P    A W+ +  + +A N+   +  NG+I  L DA    + T  QGVMSA G L NPALF   +  +  ++ A  ++DL  Q+ C +S +  HL+  W     +++  R  L  + +  G++  VNR
Sbjct:   30 LAWRLLSRRHGVQLCYTPMLHAQVFVRDANYRKENLYCEVCSEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQDEWDLLEKMVQLAHQKLSVP------------VTCKIRVFPEIE---KTVEYAKMLEKAGCQLLTVHGRTK-EQKGPLTGIASWEHIKAVRNAVNIP--VFANGNIQYLNDAERCMRETAVQGVMSAEGNLHNPALFEGRNPVV--WEMAEEYLDLVRQFPCSLSFVRAHLFKLWHHTLQVHQELREELAKVKTLEGVM-AVNR 306
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Xenopus
Match: ubash3b (ubiquitin associated and SH3 domain containing B [Source:Xenbase;Acc:XB-GENE-5757837])

HSP 1 Score: 140.969 bits (354), Expect = 1.175e-36
Identity = 99/298 (33.22%), Postives = 151/298 (50.67%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEF--SSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEP----ARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNR 1059
            L +R+L R  G  L YTPM+ A  F++    R        CS DRPLIVQF + +P   ++A+ L  +  D +DLN GCPQ  A +   G  L  E +L+ +M++    KL +P            V+ KIR+   I    +TVE  + L++ G   +TVH RT  E+  P    A W+ +  + +A N+   +  NG+I  L DA    + T  QGVMSA G L NPALF   +  +  ++ A  ++DL  Q+ C +S +  HL+  W     +++  R  L  + +  G++  VNR
Sbjct:   42 LAWRLLSRRHGVQLCYTPMLHAQVFVRDANYRKENLYCEVCSEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQDEWDLLEKMVQLAHQKLSVP------------VTCKIRVFPEIE---KTVEYAKMLEKAGCQLLTVHGRTK-EQKGPLTGIASWEHIKAVRNAVNIP--VFANGNIQYLNDAERCMRETAVQGVMSAEGNLHNPALFEGRNPVV--WEMAEEYLDLVRQFPCSLSFVRAHLFKLWHHTLQVHQELREELAKVKTLEGVM-AVNR 318
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Xenopus
Match: ubash3b (ubiquitin associated and SH3 domain containing B [Source:Xenbase;Acc:XB-GENE-5757837])

HSP 1 Score: 140.584 bits (353), Expect = 1.766e-36
Identity = 99/298 (33.22%), Postives = 151/298 (50.67%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEF--SSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEP----ARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNR 1059
            L +R+L R  G  L YTPM+ A  F++    R        CS DRPLIVQF + +P   ++A+ L  +  D +DLN GCPQ  A +   G  L  E +L+ +M++    KL +P            V+ KIR+   I    +TVE  + L++ G   +TVH RT  E+  P    A W+ +  + +A N+   +  NG+I  L DA    + T  QGVMSA G L NPALF   +  +  ++ A  ++DL  Q+ C +S +  HL+  W     +++  R  L  + +  G++  VNR
Sbjct:   73 LAWRLLSRRHGVQLCYTPMLHAQVFVRDANYRKENLYCEVCSEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQDEWDLLEKMVQLAHQKLSVP------------VTCKIRVFPEIE---KTVEYAKMLEKAGCQLLTVHGRTK-EQKGPLTGIASWEHIKAVRNAVNIP--VFANGNIQYLNDAERCMRETAVQGVMSAEGNLHNPALFEGRNPVV--WEMAEEYLDLVRQFPCSLSFVRAHLFKLWHHTLQVHQELREELAKVKTLEGVM-AVNR 349
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Mouse
Match: Dus4l (dihydrouridine synthase 4-like (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1919166])

HSP 1 Score: 227.639 bits (579), Expect = 4.687e-71
Identity = 116/289 (40.14%), Postives = 180/289 (62.28%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLIN 1047
            + + +L FR LVR+  CDL YTPMIIA  F++S KAR SEF++   D PLIVQFA+ +   L +A+ LV   A+G+D+NCGCPQ+WA+ +  G  L+ +PEL+ +M++ V+       N + S  FSVS KIRI + +   A T++L R+ +  GV W+TVH RT  ER +P  +  +  I    NVS  +V NGDI SL++A   +Q+T   GVM ARG+L NPA+F+      +   C   ++D+ ++ G      HQHL +M+E   +R ++ + +++SS++ +++
Sbjct:   35 VRYSKLAFRTLVRKYSCDLCYTPMIIAADFVRSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAALLVCPYANGIDINCGCPQRWAMADGYGACLINKPELVHDMVRQVR-------NRVESPRFSVSIKIRIHDDL---ARTIDLCRKAEATGVSWITVHGRTVEERHQPVHYDAIKMI--KENVSIPIVANGDIRSLKEAENVWQMTGTDGVMVARGLLTNPAMFAGYEE--TPLKCIWDWVDISLELGTPFMCFHQHLMYMMEKITSRQEKRVFNALSSTSAVLD 309
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Mouse
Match: Dus1l (dihydrouridine synthase 1-like (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1915980])

HSP 1 Score: 134.035 bits (336), Expect = 3.286e-34
Identity = 93/299 (31.10%), Postives = 144/299 (48.16%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEF--SSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSE---PARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNRLS 1065
            L +R+L R  G  L YTPM+ A  F++    R        C  DRPLIVQF + +P   ++A+ L  +  D +DLN GCPQ  A +   G  L +E +L+  MI     +L +P            V+ KIR+   I+   +TV   + L++ G   +TVH RT  ++      A W+ +  +  A  +   +  NG+I  LQD     Q T  QGVMSA G L NPALF   S  +  ++ A  ++D+  Q+ C +S +  HL+  W     +++  R  L  + +  G+  +   L 
Sbjct:   30 LAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCDVCPEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQEEWDLLQRMILLAHERLSVP------------VTCKIRVFPEID---KTVRYAQMLEKAGCQLLTVHGRTKEQKGPMAGTASWEHIKAVRKAVGIP--VFANGNIQCLQDVERCIQDTGVQGVMSAEGNLHNPALFEGRSPAV--WELAEEYLDIVRQHPCPLSYVRAHLFKLWHHTLQVHQQLREELAKVKTLEGVAAVSQALK 309
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Mouse
Match: Dus1l (dihydrouridine synthase 1-like (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1915980])

HSP 1 Score: 133.65 bits (335), Expect = 4.045e-34
Identity = 93/299 (31.10%), Postives = 144/299 (48.16%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEF--SSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSE---PARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNRLS 1065
            L +R+L R  G  L YTPM+ A  F++    R        C  DRPLIVQF + +P   ++A+ L  +  D +DLN GCPQ  A +   G  L +E +L+  MI     +L +P            V+ KIR+   I+   +TV   + L++ G   +TVH RT  ++      A W+ +  +  A  +   +  NG+I  LQD     Q T  QGVMSA G L NPALF   S  +  ++ A  ++D+  Q+ C +S +  HL+  W     +++  R  L  + +  G+  +   L 
Sbjct:   30 LAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCDVCPEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQEEWDLLQRMILLAHERLSVP------------VTCKIRVFPEID---KTVRYAQMLEKAGCQLLTVHGRTKEQKGPMAGTASWEHIKAVRKAVGIP--VFANGNIQCLQDVERCIQDTGVQGVMSAEGNLHNPALFEGRSPAV--WELAEEYLDIVRQHPCPLSYVRAHLFKLWHHTLQVHQQLREELAKVKTLEGVAAVSQALK 309
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Mouse
Match: Dus1l (dihydrouridine synthase 1-like (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1915980])

HSP 1 Score: 133.65 bits (335), Expect = 4.045e-34
Identity = 93/299 (31.10%), Postives = 144/299 (48.16%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEF--SSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSE---PARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNRLS 1065
            L +R+L R  G  L YTPM+ A  F++    R        C  DRPLIVQF + +P   ++A+ L  +  D +DLN GCPQ  A +   G  L +E +L+  MI     +L +P            V+ KIR+   I+   +TV   + L++ G   +TVH RT  ++      A W+ +  +  A  +   +  NG+I  LQD     Q T  QGVMSA G L NPALF   S  +  ++ A  ++D+  Q+ C +S +  HL+  W     +++  R  L  + +  G+  +   L 
Sbjct:   30 LAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCDVCPEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQEEWDLLQRMILLAHERLSVP------------VTCKIRVFPEID---KTVRYAQMLEKAGCQLLTVHGRTKEQKGPMAGTASWEHIKAVRKAVGIP--VFANGNIQCLQDVERCIQDTGVQGVMSAEGNLHNPALFEGRSPAV--WELAEEYLDIVRQHPCPLSYVRAHLFKLWHHTLQVHQQLREELAKVKTLEGVAAVSQALK 309
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Mouse
Match: Dus1l (dihydrouridine synthase 1-like (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1915980])

HSP 1 Score: 133.65 bits (335), Expect = 4.045e-34
Identity = 93/299 (31.10%), Postives = 144/299 (48.16%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEF--SSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSE---PARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNRLS 1065
            L +R+L R  G  L YTPM+ A  F++    R        C  DRPLIVQF + +P   ++A+ L  +  D +DLN GCPQ  A +   G  L +E +L+  MI     +L +P            V+ KIR+   I+   +TV   + L++ G   +TVH RT  ++      A W+ +  +  A  +   +  NG+I  LQD     Q T  QGVMSA G L NPALF   S  +  ++ A  ++D+  Q+ C +S +  HL+  W     +++  R  L  + +  G+  +   L 
Sbjct:   30 LAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCDVCPEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQEEWDLLQRMILLAHERLSVP------------VTCKIRVFPEID---KTVRYAQMLEKAGCQLLTVHGRTKEQKGPMAGTASWEHIKAVRKAVGIP--VFANGNIQCLQDVERCIQDTGVQGVMSAEGNLHNPALFEGRSPAV--WELAEEYLDIVRQHPCPLSYVRAHLFKLWHHTLQVHQQLREELAKVKTLEGVAAVSQALK 309
[Close]
BLAST of tRNA-dihydrouridine synthase vs. UniProt/SwissProt
Match: sp|O95620|DUS4L_HUMAN (tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like OS=Homo sapiens OX=9606 GN=DUS4L PE=2 SV=2)

HSP 1 Score: 233.032 bits (593), Expect = 2.353e-72
Identity = 116/289 (40.14%), Postives = 184/289 (63.67%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLIN 1047
            + + +L FR LVR+  CDL YTPMI+A  F+KS KAR SEF++   D PLIVQFA+ +   L +A+++V   A+G+D+NCGCPQ+WA+ E  G  L+ +PEL+ +M+K V+       N++ + GFSVS KIRI + +     TV+L ++ +  GV W+TVH RTA ER +P  +  +  I    N+S  ++ NGDI SL++A   +++T   GVM ARG+LANPA+F+      +   C   ++D+ ++ G      HQHL +M+E   +R ++ + +++SS++ +I+
Sbjct:   35 VRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVR-------NQVETPGFSVSIKIRIHDDLK---RTVDLCQKAEATGVSWITVHGRTAEERHQPVHYDSIKII--KENMSIPVIANGDIRSLKEAENVWRITGTDGVMVARGLLANPAMFAGYEE--TPLKCIWDWVDIALELGTPYMCFHQHLMYMMEKITSRQEKRVFNALSSTSAIID 309
[Close]
BLAST of tRNA-dihydrouridine synthase vs. UniProt/SwissProt
Match: sp|Q32M08|DUS4L_MOUSE (tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like OS=Mus musculus OX=10090 GN=Dus4l PE=2 SV=1)

HSP 1 Score: 229.18 bits (583), Expect = 7.862e-71
Identity = 117/292 (40.07%), Postives = 182/292 (62.33%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVN 1056
            + + +L FR LVR+  CDL YTPMIIA  F++S KAR SEF++   D PLIVQFA+ +   L +A+ LV   A+G+D+NCGCPQ+WA+ +  G  L+ +PEL+ +M++ V+       N + S  FSVS KIRI + +   A T++L R+ +  GV W+TVH RT  ER +P  +  +  I    NVS  +V NGDI SL++A   +Q+T   GVM ARG+LANPA+F+      +   C   ++D+ ++ G      HQHL +M+E   +R ++ + +++SS++ +++ + 
Sbjct:   35 VRYSKLAFRTLVRKYSCDLCYTPMIIAADFVRSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAALLVCPYANGIDINCGCPQRWAMADGYGACLINKPELVHDMVRQVR-------NRVESPRFSVSIKIRIHDDL---ARTIDLCRKAEATGVSWITVHGRTVEERHQPVHYDAIKMI--KENVSIPIVANGDIRSLKEAENVWQMTGTDGVMVARGLLANPAMFAGYEE--TPLKCIWDWVDISLELGTPFMCFHQHLMYMMEKITSRQEKRVFNALSSTSAVLDYLT 312
[Close]
BLAST of tRNA-dihydrouridine synthase vs. UniProt/SwissProt
Match: sp|Q09504|YQI2_CAEEL (Uncharacterized tRNA-dihydrouridine synthase-like protein C45G9.2 OS=Caenorhabditis elegans OX=6239 GN=C45G9.2 PE=3 SV=2)

HSP 1 Score: 192.586 bits (488), Expect = 3.321e-57
Identity = 109/294 (37.07%), Postives = 167/294 (56.80%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRL 1062
            + + +L FR LVR    D+ +TPMI A +F++SEK R SE S C  D PLIVQFA+ +P  L EA+++VY+ + GVDLNCGCP+     +  G +L+ +PEL+++M++  +  +PD         FSVS KIRI   I    +TV+L R+ +  GV  +TVH RT  +R+EP   + L   +   +VS  ++ NG I + ++A    + T   G+M+A G+L NPALF+      S  DC   F+ L  +YG      HQHL +ML    +   R + + ++    + + +N L
Sbjct:    2 VRYSKLAFRQLVRVYDVDVCFTPMIYAKNFIESEKCRSSELSVCEGDSPLIVQFATDDPFVLSEAAEMVYKCSTGVDLNCGCPKHDVRSKGFGSALLSKPELLADMVRQTRARIPD-------PDFSVSLKIRINHDIE---KTVDLCRKAEAAGVTHLTVHGRTPSQRAEPIDIQALR--IVKDSVSVPIIANGGITTREEALFLAEQTGVDGIMAANGLLDNPALFAGHEHTPS--DCVENFMRLSREYGLDWLLYHQHLQYMLRPVFSAQQRRVFNELNGRLAIDHFLNNL 281
[Close]
BLAST of tRNA-dihydrouridine synthase vs. UniProt/SwissProt
Match: sp|Q06063|DUS4_YEAST (tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+] OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DUS4 PE=1 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 1.021e-51
Identity = 110/304 (36.18%), Postives = 169/304 (55.59%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVER-SEPARW---KQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQ-HLYWMLEG-DLNRSDRTLLHSMSSSAGLINIVNRLSSWK 1074
            + + +LPFR L RE   D+ Y+PMI+A  ++++E AR S+ S+ + D PLIVQ    N  +LL+  ++V    DG+ +NCGCP K  I+E IGC+L+   +L+  M+  VK        + + +   +  KIRI E ++   ETVEL R+L   GVDW+T+H RT   R S+PA     K + E +S  NV   ++ NGD   L D     + T   GVM+ RG+L+NPALF+  ++    + C   F    +++G    QL Q HLY MLE  +L +S    + ++ +   LI+  N+   +K
Sbjct:   47 VRYSKLPFRQLCREYNVDIVYSPMILAREYVRNEHARISDLSTNNEDTPLIVQVGVNNVADLLKFVEMVAPYCDGIGINCGCPIKEQIREGIGCALIYNSDLLCSMVHAVK--------DKYGDKLRIETKIRIHEALD---ETVELCRKLCDAGVDWITIHGRTRRTRSSQPANLDAIKYIIENISDKNVP--VIANGDCFKLSDLERITKYTGAHGVMAVRGLLSNPALFAGYTT--CPWGCIEKFCYWALEFGGLPFQLAQHHLYCMLENMELKKSLLKKMMNLKNYISLIDWFNKTFEFK 335
[Close]
BLAST of tRNA-dihydrouridine synthase vs. UniProt/SwissProt
Match: sp|O74553|DUS4_SCHPO (tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+] OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=dus4 PE=3 SV=1)

HSP 1 Score: 179.104 bits (453), Expect = 1.833e-51
Identity = 98/267 (36.70%), Postives = 148/267 (55.43%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSE-PARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWML 978
            + + +LPFR LVR+   D+ YTPMI+A  FL   K RY +FS+  +D  LI+QF   +P  L +A++LV    DG+ +NCGCPQ WAIQE IG +L+ EPE + ++++ VK  +           F    KIRI + +N   +T  L++ +++ G D +TVH RT  +RS  P     + E+     +   +V NGD+ SL+   E  + T+ QG+MSARG+L NPALF+      + + C   F+     Y       + HL  M+
Sbjct:   28 VRYSKLPFRQLVRDYNTDIVYTPMILAKEFLHP-KGRYFDFSTNDADASLILQFGVDDPVILEKAAQLVGPYVDGIGINCGCPQTWAIQEGIGSALLDEPEKVHKLVRAVKSTL--------GESFCTEVKIRIAKDLN---KTRHLMQVIEKSGADIITVHGRTRQDRSSFPVNLDAIREVRPCVQIP--VVANGDVKSLRKGLEIAKYTETQGIMSARGLLENPALFAGYEE--TPWGCVERFLWYSTSYSLNFHLFYHHLTTMM 278
[Close]
BLAST of tRNA-dihydrouridine synthase vs. TrEMBL
Match: T1EEB6 (tRNA-dihydrouridine synthase OS=Helobdella robusta OX=6412 GN=20194918 PE=3 SV=1)

HSP 1 Score: 270.781 bits (691), Expect = 1.397e-84
Identity = 128/291 (43.99%), Postives = 193/291 (66.32%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIV 1053
            + +  LPFR+LVR+ GCDLAYTPMIIADSF+KSEKAR ++F +  +DRPL+VQFA+ + +   EAS  V   ADGVDLNCGCPQ+WA+++  GC L+K+PEL+ +++KT+K       N IH   FS+S KIR+   ++   +T+E+ RR++R+G  W+TVHART  ++ +PA W  L +IV +  +   +V NGDI S+ D  +   VT  +GVMSARG+L NPAL++      +  +C + +++L  +Y     + H HL +MLE  L + DR   + M+S+  +++ +
Sbjct:   28 VRYSSLPFRLLVRKYGCDLAYTPMIIADSFVKSEKARANDFVTNLNDRPLVVQFAANDASVFAEASAFVINYADGVDLNCGCPQRWAMRDGYGCCLLKKPELMEDIVKTLK-------NRIHRRDFSISVKIRL---LHDLGKTIEICRRMERIGCSWITVHARTPDQKHQPANWDPLKDIVDSLKIP--VVANGDIKSMNDVTKVVNVTGVKGVMSARGLLGNPALYN--GCERTPKECVQDWVNLAAKYSVTGQRFHNHLIYMLEKSLTKDDRKFFNCMTSTTDVLDFL 304
[Close]
BLAST of tRNA-dihydrouridine synthase vs. TrEMBL
Match: A0A1I8GWF9 (tRNA-dihydrouridine synthase OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 260.766 bits (665), Expect = 1.155e-80
Identity = 132/301 (43.85%), Postives = 181/301 (60.13%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRLSSWKLSA 1083
            + + +LPFR LVR+ GCDL YTPMI+A SFL S+KAR +EF +   DRPLIVQFAS +P E     +LV    DGVDLNCGCPQ+WA Q+ +G  L  +P+L++EM    +  +         N F++SAKIR+C  +    +T  L   LD+ G DW+TVH RT  +R EPA W+ L  + S       LV NGD+ +L DA+    +T C GVMSARG++ NPA+FS E    +  +C R F+ L +  G      H HL  MLE  L+R++    + ++S A +I+ VNR   W L+A
Sbjct:   25 VRYSKLPFRYLVRQYGCDLCYTPMIVASSFLCSDKARDNEFVTGPGDRPLIVQFASNDPAEFAACVRLVEPHCDGVDLNCGCPQRWANQQNLGVCLCSQPQLLAEMFTAARAAL------RCPNKFALSAKIRLCPDMR---DTERLCLTLDKAGADWITVHCRTPTQRHEPADWEALARLRSILPTRIALVANGDVFNLLDADRLHSLTGCLGVMSARGLIRNPAMFSPERPLTTPNECVRRFLWLSLSLGLPYPVFHYHLVHMLEDRLSRAEAHFFNYLTSVAAVIDFVNR---WVLNA 313
[Close]
BLAST of tRNA-dihydrouridine synthase vs. TrEMBL
Match: A0A1I8I930 (tRNA-dihydrouridine synthase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig019461g1 PE=3 SV=1)

HSP 1 Score: 258.07 bits (658), Expect = 1.443e-79
Identity = 130/301 (43.19%), Postives = 182/301 (60.47%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRLSSWKLSA 1083
            + + +LPFR L+R+ GCDL YTPMI+A SFL S+KAR +EF +   DRPLIVQFAS +P E     +LV    DGVDLNCGCPQ+WA Q+ +G  L  +P+L++EM+   +  +         N F++SAKIR+C  +    +T  L   L++ G DW+TVH RT  +R EPA W+ L  + S       LV NGD+ +L DA+    +T C GVMSARG++ NPA+FS E    +  +C R F+ L +  G      H HL  MLE  L+R++    + ++S A +I+ VNR   W L+A
Sbjct:   26 VRYSKLPFRYLMRQYGCDLCYTPMIVASSFLCSDKARDNEFVTGPGDRPLIVQFASNDPAEFAACVQLVEPHCDGVDLNCGCPQRWANQQNLGVCLCSQPQLLAEMLTAARAAL------RCPNKFALSAKIRLCPDMR---DTERLCLTLEKAGADWITVHCRTPTQRHEPADWEALARLRSVLPTRIALVANGDVFNLLDADRLHSLTGCLGVMSARGLIRNPAMFSPERPLTTPNECVRRFLWLSLSLGLPYPVFHYHLVHMLEDRLSRAEAHFFNYLTSVAAVIDFVNR---WVLNA 314
[Close]
BLAST of tRNA-dihydrouridine synthase vs. TrEMBL
Match: A0A5N5SJQ4 (tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like OS=Armadillidium nasatum OX=96803 GN=DUS4L_0 PE=4 SV=1)

HSP 1 Score: 256.914 bits (655), Expect = 3.076e-79
Identity = 128/300 (42.67%), Postives = 195/300 (65.00%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRLSSWKLS 1080
            + + +L FR LVR+ GCDL +TPMI+ADSF+KS+ AR ++F+ C SDRPLIVQFAS N      A++LVY  +DGVDLNCGCPQ+WAIQE  G  L+ +PEL+S++I   +       N I  + FSVS KIRI    N T  TV+  R+++  G+ +++VH RT  +RSEP  ++ +  I S+ N+   ++ NGDI +L +A    ++T   GVM ARG+LANP+LFS   +  ++ DC + +I + I+ G   +  H HL +M+E   +R+DR   +++SS +G+++ + +  S+ +S
Sbjct:   25 VRYSKLAFRNLVRKYGCDLCFTPMIVADSFIKSKNARDNDFTYCKSDRPLIVQFASSNAENFRHAAELVYPYSDGVDLNCGCPQRWAIQEGYGACLINKPELVSDIIHQTR-------NAICDSEFSVSLKIRIH---NDTKRTVDFARQMESAGLTFLSVHGRTKEQRSEPVNYEAISLIKSSINIP--VIANGDIKTLNEAEHIKKLTNVDGVMCARGLLANPSLFS--GTEFTTLDCVKDWIKIAIETGTPFTCFHNHLIYMIEKLQSRADRRYFNALSSVSGVVSFLEQKYSFDVS 310
[Close]
BLAST of tRNA-dihydrouridine synthase vs. TrEMBL
Match: A0A4D5RL37 (Putative trna-dihydrouridine synthase (Fragment) OS=Ixodes scapularis OX=6945 PE=4 SV=1)

HSP 1 Score: 256.914 bits (655), Expect = 4.465e-79
Identity = 126/303 (41.58%), Postives = 196/303 (64.69%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIV-NRLSSWKLSAS 1086
            + + +  FRMLVR    D+AYTPMII+DSF+KS+KAR +EF++   DRPLIVQFA+ N  +L  AS+LVY  ADGVDLNCGCPQ+WA+ E  G  L+ +PEL+ +M+   +       N +   GF++S KIRICE +    +TV++ ++L+   V +VTVH RT  +RSEP   + +  +  A  +   +V NGD+ SLQ+A+  ++ T   GVM+ARG+L NPA+F  + +  +   C R ++ L  Q GC ++Q H HL +MLE  L RS++ + ++++SS+ +++ + +    W +S++
Sbjct:   26 VRYSKQAFRMLVRRYSVDVAYTPMIISDSFVKSQKARDAEFTTGPGDRPLIVQFAANNATDLANASELVYPYADGVDLNCGCPQRWAMAEGYGAHLLSDPELVRDMVHQTR-------NRLSDPGFTMSVKIRICEDMR---KTVDMCQKLEAARVSFVTVHGRTKDQRSEPVNLEAIKNVKDALRIP--VVANGDVTSLQEADRVYRATGTNGVMAARGLLENPAMF--QGAEHTPASCVRDWLRLSTQLGCPLAQFHHHLMFMLEHVLPRSEKRVFNALTSSSAVVDYLRDSYGLWDVSST 314
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Cavefish
Match: dus4l (dihydrouridine synthase 4 like [Source:NCBI gene;Acc:103044370])

HSP 1 Score: 234.958 bits (598), Expect = 2.553e-74
Identity = 115/289 (39.79%), Postives = 187/289 (64.71%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLIN 1047
            + + +L FR LVR+  CD+ YTPMI+A  F++S KAR SEF++ +SDRPLI+QFA+++   L +A+ +V   +DGVDLNCGCPQ+WA+ E  G  L+ +P+L+ +M++ VK       N+I +  ++VS KIRI + +    +TV+L ++ +  GV W+TVH RTA+ER +P  +  +  I  +  +S  ++ NGDI ++QD    +++T   GVMSARG+LANPALF+      +   C   ++D+ ++ G   +  HQHL +MLE   ++ +R + +S+SS + + +
Sbjct:   17 VRYSKLSFRSLVRKYECDMCYTPMIVAADFMRSVKARDSEFTTNNSDRPLIIQFAAKDAQTLADAACVVAPFSDGVDLNCGCPQRWAMAEGYGACLINKPQLVKDMVRHVK-------NQIDNPNYAVSIKIRIHKDVR---KTVDLCQKAEAAGVSWITVHGRTALERHQPVHYNAIKTIKDS--LSIPVIANGDIKNVQDVESIYELTGVDGVMSARGLLANPALFA--GYEYTPLKCVWDWVDIALEQGTPFTCFHQHLIYMLERITSQPERKIFNSLSSISAVTD 291
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Cavefish
Match: dus1l (dihydrouridine synthase 1 like [Source:NCBI gene;Acc:103021876])

HSP 1 Score: 122.865 bits (307), Expect = 1.908e-30
Identity = 95/302 (31.46%), Postives = 146/302 (48.34%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKAR----YSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEP---ARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQY-GCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNRLS 1065
            L +R+L R  G  L YTPM+ A  FL+    R    Y++ S    DRPLI QF + +P   ++A+ L  +  D +DLN GCPQ  A +   G  L  E EL+  MI+    KL +P            ++ KIR+   +    +TV+  + L+R G   +TVH RT  ++      A W+ +  +  A  VS  +  NG+I  L D       T  QGVMSA G L NPALF   S  +  ++ A  ++++  ++  C +S +  HL+  W     +++  R  L    + AGL  +  +L 
Sbjct:   30 LAWRLLSRRHGIQLCYTPMLHAQVFLRDANYRRENLYNDVSP--EDRPLITQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGVFLQDEWELLERMIQLANEKLSVP------------ITCKIRVFPELE---KTVKYAKMLERAGCQLLTVHGRTKDQKGAQTGVASWEHIKAVRDA--VSIPVFANGNIQHLTDVQRCLDETGVQGVMSAEGNLHNPALFEGCSPPV--WEMAEEYLEVVQKHPPCTLSFVRAHLFKLWHHTLQIHQDLREELAKAKNLAGLEEVNRQLK 310
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Cavefish
Match: dus1l (dihydrouridine synthase 1 like [Source:NCBI gene;Acc:103021876])

HSP 1 Score: 122.479 bits (306), Expect = 3.640e-30
Identity = 95/302 (31.46%), Postives = 146/302 (48.34%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKAR----YSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEP---ARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQY-GCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNRLS 1065
            L +R+L R  G  L YTPM+ A  FL+    R    Y++ S    DRPLI QF + +P   ++A+ L  +  D +DLN GCPQ  A +   G  L  E EL+  MI+    KL +P            ++ KIR+   +    +TV+  + L+R G   +TVH RT  ++      A W+ +  +  A  VS  +  NG+I  L D       T  QGVMSA G L NPALF   S  +  ++ A  ++++  ++  C +S +  HL+  W     +++  R  L    + AGL  +  +L 
Sbjct:   30 LAWRLLSRRHGIQLCYTPMLHAQVFLRDANYRRENLYNDVSP--EDRPLITQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGVFLQDEWELLERMIQLANEKLSVP------------ITCKIRVFPELE---KTVKYAKMLERAGCQLLTVHGRTKDQKGAQTGVASWEHIKAVRDA--VSIPVFANGNIQHLTDVQRCLDETGVQGVMSAEGNLHNPALFEGCSPPV--WEMAEEYLEVVQKHPPCTLSFVRAHLFKLWHHTLQIHQDLREELAKAKNLAGLEEVNRQLK 310
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Cavefish
Match: dus2 (dihydrouridine synthase 2 [Source:NCBI gene;Acc:103030766])

HSP 1 Score: 90.1225 bits (222), Expect = 4.070e-19
Identity = 73/326 (22.39%), Postives = 142/326 (43.56%), Query Frame = 1 
Query:  157 NQIYFIYNLNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKA--------------RYSEFSSCSSDRPLIV-QFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERS-EPARWKQLGEIVSAANVSCGLVVNG----DIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRLSSWK 1074
            N+I     +    LP R+L  + G D+ Y   +I     + E+                   F +CS ++  +V Q  + +P+  L  ++LV      +D+N GCP++++ +  +G +L+ +PE I  ++ T+  G+             V+ KIRI   +    ETV L++R+++ GV  + VH R   ER   P     +  +  A NVS  ++ NG     + + QD  +  + +    VM AR  + NP++F ++ + +   +    +I   ++Y          +  ML+  +       LH+  ++A +  +      +K
Sbjct:   12 NKIILAPMVRVGTLPMRLLALDYGADIVYCEELIDIKMAQCERVVNDVLDTVDFIAPDERVMFRTCSKEKDRVVFQMGTADPDRALAVAQLVENDVAAIDVNMGCPKEYSTKGGMGSALLSDPEKIETILTTLVRGV----------SKPVTCKIRILPTLE---ETVSLVKRIEKTGVAAIAVHGRMKDERQRHPVHCDYIQAV--AENVSIPVIANGGSQDHVKTYQDIEKFREASGASSVMLARAAMWNPSIFRSQGA-LPVDEAIEEYIKYAVRYDNNTFNTKYCVCQMLKDRVESPMGKQLHAAQTNAEICEVFGMTDFYK 321
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Sea Lamprey
Match: dus3l (dihydrouridine synthase 3-like (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-040426-1260])

HSP 1 Score: 82.4185 bits (202), Expect = 3.084e-17
Identity = 71/270 (26.30%), Postives = 128/270 (47.41%), Query Frame = 1 
Query:  157 NQIYFIYNLNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESA--DGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETV-ELLRRLDRMGVDWVTVHARTAVER-SEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSR----ISS---FDCARMFIDLGIQY 933
            +++Y         LPFR + +  G D+    M +  + L+ + + ++      ++    +Q     P+ + + ++L+ ++   D VD+N GCP    I +  GC+LM       ++++    GM  V++        ++AKIR   G+     T  +L+  L   G+  VT+H R+  +R ++ A WK +      A+    L  NGD++S +D + A Q T+  GVM ARG L  P +F+    R    ISS   F+  R F   G+++
Sbjct:  296 DKLYLAPLTTCGNLPFRRICKMQGADITCGEMAMCTNLLQGQMSEWALLKRHHTEDIFGIQLEGGFPDTMTKCAELLNQNVEMDFVDINVGCPIDLVINKGGGCALMNRGLKFEQIVR----GMVSVLD------VPLTAKIRT--GVQEKTNTAHKLIPELRDWGISMVTLHGRSREQRYTKLADWKYIDYCAEVAS-PLPLFGNGDVLSYEDMDLARQ-TKVAGVMIARGALVKPWIFTEIKGRRHWDISSHERFELLRDFTKYGLEH 551
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Yeast
Match: DUS4 (Dihydrouridine synthase; member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus3p [Source:SGD;Acc:S000004397])

HSP 1 Score: 181.03 bits (458), Expect = 1.470e-53
Identity = 110/304 (36.18%), Postives = 169/304 (55.59%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVER-SEPARW---KQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQ-HLYWMLEG-DLNRSDRTLLHSMSSSAGLINIVNRLSSWK 1074
            + + +LPFR L RE   D+ Y+PMI+A  ++++E AR S+ S+ + D PLIVQ    N  +LL+  ++V    DG+ +NCGCP K  I+E IGC+L+   +L+  M+  VK        + + +   +  KIRI E ++   ETVEL R+L   GVDW+T+H RT   R S+PA     K + E +S  NV   ++ NGD   L D     + T   GVM+ RG+L+NPALF+  ++    + C   F    +++G    QL Q HLY MLE  +L +S    + ++ +   LI+  N+   +K
Sbjct:   47 VRYSKLPFRQLCREYNVDIVYSPMILAREYVRNEHARISDLSTNNEDTPLIVQVGVNNVADLLKFVEMVAPYCDGIGINCGCPIKEQIREGIGCALIYNSDLLCSMVHAVK--------DKYGDKLRIETKIRIHEALD---ETVELCRKLCDAGVDWITIHGRTRRTRSSQPANLDAIKYIIENISDKNVP--VIANGDCFKLSDLERITKYTGAHGVMAVRGLLSNPALFAGYTT--CPWGCIEKFCYWALEFGGLPFQLAQHHLYCMLENMELKKSLLKKMMNLKNYISLIDWFNKTFEFK 335
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Yeast
Match: DUS1 (Dihydrouridine synthase; member of a widespread family of conserved proteins including Smm1p, Dus3p, and Dus4p; modifies pre-tRNA(Phe) at U17 [Source:SGD;Acc:S000004545])

HSP 1 Score: 119.783 bits (299), Expect = 1.692e-30
Identity = 81/236 (34.32%), Postives = 120/236 (50.85%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSS---CSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSN-GFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEP---ARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSR 882
            L +R+L R  G  LAYTPM+ A  F  S+K R   +SS    S DRPL+VQF + +P  LL A+KLV +  D VDLN GCPQ  A +   G  LM+E +LI            ++IN +H N    V+AKIRI +    +    +++  LD  G  ++TVH R   ++ +    A W+ +  +            NG+I+  +D +   +      VMSA G L NP +F+   ++
Sbjct:   42 LAWRILSRRYGATLAYTPMLHAKLFATSKKYREDNWSSLDGSSVDRPLVVQFCANDPEYLLAAAKLVEDKCDAVDLNLGCPQGIAKKGHYGSFLMEEWDLIH-----------NLINTLHKNLKVPVTAKIRIFDDCEKSLNYAKMV--LD-AGAQFLTVHGRVREQKGQKTGLANWETIKYLRDNLPKETVFFANGNILYPEDISRCMEHIGADAVMSAEGNLYNPGVFNVGQTK 263
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Yeast
Match: SMM1 (Dihydrouridine synthase; member of a family of dihydrouridine synthases including Dus1p, Smm1p, Dus3p, and Dus4p; modifies uridine residues at position 20 of cytoplasmic tRNAs [Source:SGD;Acc:S000005298])

HSP 1 Score: 70.8626 bits (172), Expect = 6.925e-14
Identity = 62/222 (27.93%), Postives = 102/222 (45.95%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCS-------SDRP---------------LIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPE----LISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAV--ERSEPAR--WKQLGEIVSAANVSCGLVVNGDI 771
            LP R++    G DL ++P II    ++  +   +   +           RP               LI Q  S +P    +A+  V     G+D+N GCP+ ++I   +G +L++ P+    ++ E++K V  G P      HS   SV  KIR+   ++   +T++L++RL   G+  +TVH R      R +P      ++ EI  A NVS  L+VNG I
Sbjct:   19 LPTRLMALAHGADLVWSPEIIDKKLIQCVRKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNV--GNP------HSKPISV--KIRL---LDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVS--LIVNGAI 225
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Yeast
Match: DUS3 (Dihydrouridine synthase; member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus4p; contains a consensus oleate response element (ORE) in its promoter region; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000004393])

HSP 1 Score: 49.2914 bits (116), Expect = 7.502e-7
Identity = 61/253 (24.11%), Postives = 112/253 (44.27%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRP-LIVQFASRNPNELLEASKLVYESA---DGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAE----TVELLRRL-DRMGVDWVTVHARTAVER-SEPARWK---QLGEIVSAANVS----------------CGLVVNGDIMSLQDANEAFQVTQ-CQGVMSARGILANPALF 864
            LP+R L+R+LG D+ Y+ M +A   ++   + ++   + +S+ P   VQ A     +  +A++ +  S      ++LN GCP     ++  G +L+  P   + MI+ +     + +N + S    ++ KIR      GT E       L++RL +   V  +T+H R+  +R ++ A W    Q+ + + +A                      V NGD+ + +D        +    VM ARG L  P +F
Sbjct:  306 LPYRRLMRKLGADVTYSEMALAVPLIQGTNSEWALPKAHTSEFPGFGVQVACSKAWQAAKAAEALANSVSEISEINLNSGCPIDLLYRQGSGSALLDNP---ARMIRCL-----NAMNYV-SKDIPITVKIRT-----GTKEGHPIAEGLVKRLVNETDVAAITLHGRSRQQRYTKSADWDYVSQVADTLRSAEADFIETEQGKEGRDSKNRIQFVGNGDVNNFEDWYRYLNGNENIDSVMVARGALIKPWIF 544
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Nematostella
Match: EDO46952 (tRNA-dihydrouridine synthase [Source:UniProtKB/TrEMBL;Acc:A7RNM3])

HSP 1 Score: 227.639 bits (579), Expect = 1.381e-71
Identity = 110/289 (38.06%), Postives = 182/289 (62.98%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLIN 1047
            + + +L FR LVR   CDL +TPMII++SF+KS+KAR SEF++ S DRP++VQFA+    +L +A++++    DGVDLNCGCPQ+WAIQE+ G  L+ +PEL+ +M++  K  +          G  VS KIRI +      +TV+L +R +  G  W+T+H RT+ +R+EP   + +  +    N+S  +V NGDI    D  +  + T   GVM+ARGIL+NPA+++  S  ++  +C + +ID+ +  G   +  H HL +M+E    ++++ + +S+ S++G+++
Sbjct:   36 VRYSKLSFRELVRRYDCDLCFTPMIISESFVKSQKARDSEFTTNSGDRPIVVQFAANCAKDLADATEIISPFVDGVDLNCGCPQRWAIQERYGAHLINQPELVKDMVRQTKSRV---------TGIPVSIKIRIHQ---DKRKTVDLCKRAEHAGASWITIHGRTSKQRTEPPSMETIKLV--KENLSIPVVANGDIRCTDDFLKVCEATGANGVMAARGILSNPAMYAGYS--VTPVECIKDWIDISLSLGTSFTIFHHHLLYMMEKITTKAEKRVFNSLKSTSGVLD 308
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Nematostella
Match: EDO34286 (tRNA-dihydrouridine synthase [Source:UniProtKB/TrEMBL;Acc:A7SPU7])

HSP 1 Score: 144.436 bits (363), Expect = 3.743e-40
Identity = 88/263 (33.46%), Postives = 133/263 (50.57%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSE---PARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLY 969
            L +RML R  G +L YTPM  A  F++    R     +C  DRPLIVQF + +P   ++A+ LV    DGVDLN GCPQ  A +   G  L  E EL+ +M+K    KL +P            ++ KIR+ + +    +T+   + L+  G   +TVH RT  ++ E    A W Q+  +    N+   +  NG+I  L D     + T C GVM+A G L+NPALF+     + S   A  +++L  ++   +S +  HL+
Sbjct:   39 LAWRMLSRRYGAELCYTPMFHAGMFIRDPIYRSEMMQTCVGDRPLIVQFCANDPEVFVQAALLVESECDGVDLNLGCPQHIAKRGHYGAFLQDEWELLEKMVKLAHEKLSVP------------ITCKIRVFDDVQ---KTIAYAKMLESAGCQLLTVHGRTREQKRELTGLADWDQIKAVRENLNIP--VFANGNIQYLSDVTRCLEYTGCNGVMTAEGNLSNPALFTGSQPYVWSM--ANEYLELATKHKASLSAVRAHLF 282
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Nematostella
Match: EDO42155 (tRNA-dihydrouridine(47) synthase [NAD(P)(+)] [Source:UniProtKB/TrEMBL;Acc:A7S213])

HSP 1 Score: 87.8113 bits (216), Expect = 1.123e-18
Identity = 65/272 (23.90%), Postives = 127/272 (46.69%), Query Frame = 1 
Query:  157 NQIYFIYNLNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESA--DGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETV---ELLRRLDRMGVDWVTVHARTAVER-SEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFST-------ESSRISSFDCARMFIDLGIQY 933
            +++Y         LPFR + ++ G D+    M +  + L+ +++ ++     SS+    VQ     P+ + + ++L+ +    D +D+N GCP      +  G +LM+    + ++++    GM  VI+        +   ++I  GI+    T    +L+  L   G D VT+H R+  +R ++ A W  + E+   A+    +  NGDI+S +DA +  +     GVM ARG +  P +F+        + S     D  R F++ G+++
Sbjct:  218 DKLYLAPLTTIGNLPFRRICKQYGADITCGEMAMCTNLLQGQQSEWALVKRHSSEDIFGVQLCGAFPDTMTKCAELLQKETDVDFIDINTGCPIDLVFNKGAGSALMERKGKLQQIVQ----GMKSVID--------IPLTVKIRAGIHDKKYTWNAHKLVGNLRDWGTDMVTIHGRSREQRYTKSADWDYISEVAKLAS-PMPVFGNGDILSFEDAMQHRKQAGVAGVMIARGAIIKPWIFTEIKEQRHWDISSSERLDILRQFVNAGLEH 476
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Nematostella
Match: EDO39241 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAL7])

HSP 1 Score: 83.5741 bits (205), Expect = 1.676e-17
Identity = 69/275 (25.09%), Postives = 121/275 (44.00%), Query Frame = 1 
Query:  157 NQIYFIYNLNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYS--------------EFSSCSSDRPLIV-QFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNG--DIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQ 930
            N+ +    +    LP R+L    G DL YT  II    L++ + +                 F +C  +   +V Q  + + +  L+ +K+V +     D+N GCP+ ++++  +G +L+ EPE + +++ T+  G+             V+ KIRI   I   AETV+L + ++  GV  + VH R   ERS      +  + V+AA     +   G  DI +  D  +      C  +M AR    N ++F  E   +S  D  + +I   I+
Sbjct:    4 NKYFLAPMVRIGTLPARLLALRYGADLVYTEEIIDFKMLRTTRVKNELLNTVDFVMSDGTVVFRTCQEETTHVVFQVGTADADRALQVAKMVEKDIAAFDVNMGCPKDYSVKGGMGAALLTEPEKVKKILTTLVKGL----------SIPVTCKIRILPTI---AETVQLCKLIESTGVTALAVHGREKHERSRQPVHTEYIQAVAAAVAIPVIANGGSLDIKTFSDMEQFRLQAGCASIMVARAAQWNLSVFRREGP-LSHLDVVKAYIKTAIE 264
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Medaka
Match: dus4l (dihydrouridine synthase 4 like [Source:NCBI gene;Acc:101172995])

HSP 1 Score: 231.876 bits (590), Expect = 8.603e-73
Identity = 116/289 (40.14%), Postives = 182/289 (62.98%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLIN 1047
            + + +L FR LVR+  CD+ +TPMIIA  FL+S KAR SEF++  SDRPLIVQFA+++P  L +A+ +V   +DGVDLNCGCPQ+WA+    G  L+ +PEL+ +M++ V+       N++ +  ++VS KIRI + +    +TV+L ++ +  GV W+TVH RT  ER +P  +  +  I  +  VS  ++ NGDI  L+D     Q T   GVM+ARG+LANPA+F+      +   C   ++D+ ++ G   S  H HL +MLE   ++ +R + +S+SS++ +I+
Sbjct:   27 VRYSKLAFRSLVRKYSCDVCFTPMIIAADFLRSVKARDSEFTTNKSDRPLIVQFAAQDPQTLADAACVVAPFSDGVDLNCGCPQRWAMSAGYGACLINKPELVEDMVRHVR-------NQVDNPDYTVSIKIRIHKDLR---QTVDLCQKAESAGVSWITVHGRTTEERHQPVHYDAIKTIKDS--VSVPVIANGDIKYLRDVESTHQHTGVNGVMAARGLLANPAMFAGYED--TPLQCIWDWVDIAVEQGTPFSCFHHHLIYMLERVSSQPERKVFNSLSSTSAVID 301
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Medaka
Match: dus4l (dihydrouridine synthase 4 like [Source:NCBI gene;Acc:101172995])

HSP 1 Score: 231.106 bits (588), Expect = 2.140e-72
Identity = 116/289 (40.14%), Postives = 182/289 (62.98%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLIN 1047
            + + +L FR LVR+  CD+ +TPMIIA  FL+S KAR SEF++  SDRPLIVQFA+++P  L +A+ +V   +DGVDLNCGCPQ+WA+    G  L+ +PEL+ +M++ V+       N++ +  ++VS KIRI + +    +TV+L ++ +  GV W+TVH RT  ER +P  +  +  I  +  VS  ++ NGDI  L+D     Q T   GVM+ARG+LANPA+F+      +   C   ++D+ ++ G   S  H HL +MLE   ++ +R + +S+SS++ +I+
Sbjct:   37 VRYSKLAFRSLVRKYSCDVCFTPMIIAADFLRSVKARDSEFTTNKSDRPLIVQFAAQDPQTLADAACVVAPFSDGVDLNCGCPQRWAMSAGYGACLINKPELVEDMVRHVR-------NQVDNPDYTVSIKIRIHKDLR---QTVDLCQKAESAGVSWITVHGRTTEERHQPVHYDAIKTIKDS--VSVPVIANGDIKYLRDVESTHQHTGVNGVMAARGLLANPAMFAGYED--TPLQCIWDWVDIAVEQGTPFSCFHHHLIYMLERVSSQPERKVFNSLSSTSAVID 311
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Medaka
Match: dus1l (dihydrouridine synthase 1 like [Source:NCBI gene;Acc:101173228])

HSP 1 Score: 129.028 bits (323), Expect = 6.769e-33
Identity = 95/301 (31.56%), Postives = 146/301 (48.50%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKAR----YSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVER---SEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQY-GCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNRL 1062
            L +R+L R  G  L YTPM  A  F++    R    YSE   C  DRPLI QF + +P   ++A+ L  +  D VDLN GCPQ  A +   G  L  E +L+  MI+    KL +P            V+ KIR+ E +     TV   + L++ G   +TVH RT  ++   +  A W+ +  +  A N+   +  NG+I  L D     Q T  QGVMSA G L NPALF   S  +  ++ A  ++++  ++  C +S +  HL+  W     +++  R  L  + +   L  + ++L
Sbjct:   30 LAWRLLSRRHGAQLCYTPMFHAQVFVRDANYRRENLYSEV--CEEDRPLITQFCANDPEVFVQAALLAQDYCDAVDLNLGCPQMIAKRGHYGVFLQDEWDLLERMIRLAHEKLSVP------------VTCKIRVFEDVE---RTVRYAQMLEKAGCQLLTVHGRTKDQKGPMTGVASWEHIKAVRKAVNIP--VFANGNIQHLGDVERCIQETGVQGVMSAEGNLHNPALFEGRSPPV--WEMADEYLEVVQRHPPCSLSYVRAHLFKLWHHTLQIHQDLREELAKVKTLQALAEVSSQL 309
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Medaka
Match: dus1l (dihydrouridine synthase 1 like [Source:NCBI gene;Acc:101173228])

HSP 1 Score: 128.257 bits (321), Expect = 4.769e-32
Identity = 95/301 (31.56%), Postives = 146/301 (48.50%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKAR----YSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVER---SEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQY-GCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNRL 1062
            L +R+L R  G  L YTPM  A  F++    R    YSE   C  DRPLI QF + +P   ++A+ L  +  D VDLN GCPQ  A +   G  L  E +L+  MI+    KL +P            V+ KIR+ E +     TV   + L++ G   +TVH RT  ++   +  A W+ +  +  A N+   +  NG+I  L D     Q T  QGVMSA G L NPALF   S  +  ++ A  ++++  ++  C +S +  HL+  W     +++  R  L  + +   L  + ++L
Sbjct:   30 LAWRLLSRRHGAQLCYTPMFHAQVFVRDANYRRENLYSEV--CEEDRPLITQFCANDPEVFVQAALLAQDYCDAVDLNLGCPQMIAKRGHYGVFLQDEWDLLERMIRLAHEKLSVP------------VTCKIRVFEDVE---RTVRYAQMLEKAGCQLLTVHGRTKDQKGPMTGVASWEHIKAVRKAVNIP--VFANGNIQHLGDVERCIQETGVQGVMSAEGNLHNPALFEGRSPPV--WEMADEYLEVVQRHPPCSLSYVRAHLFKLWHHTLQIHQDLREELAKVKTLQALAEVSSQL 309
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Medaka
Match: dus1l (dihydrouridine synthase 1 like [Source:NCBI gene;Acc:101173228])

HSP 1 Score: 128.257 bits (321), Expect = 8.032e-32
Identity = 95/301 (31.56%), Postives = 146/301 (48.50%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKAR----YSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTV--KLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVER---SEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQY-GCQISQLHQHLY--WMLEGDLNRSDRTLLHSMSSSAGLINIVNRL 1062
            L +R+L R  G  L YTPM  A  F++    R    YSE   C  DRPLI QF + +P   ++A+ L  +  D VDLN GCPQ  A +   G  L  E +L+  MI+    KL +P            V+ KIR+ E +     TV   + L++ G   +TVH RT  ++   +  A W+ +  +  A N+   +  NG+I  L D     Q T  QGVMSA G L NPALF   S  +  ++ A  ++++  ++  C +S +  HL+  W     +++  R  L  + +   L  + ++L
Sbjct:  115 LAWRLLSRRHGAQLCYTPMFHAQVFVRDANYRRENLYSEV--CEEDRPLITQFCANDPEVFVQAALLAQDYCDAVDLNLGCPQMIAKRGHYGVFLQDEWDLLERMIRLAHEKLSVP------------VTCKIRVFEDVE---RTVRYAQMLEKAGCQLLTVHGRTKDQKGPMTGVASWEHIKAVRKAVNIP--VFANGNIQHLGDVERCIQETGVQGVMSAEGNLHNPALFEGRSPPV--WEMADEYLEVVQRHPPCSLSYVRAHLFKLWHHTLQIHQDLREELAKVKTLQALAEVSSQL 394
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Planmine SMEST
Match: SMESG000002913.1 (SMESG000002913.1)

HSP 1 Score: 616.69 bits (1589), Expect = 0.000e+0
Identity = 297/302 (98.34%), Postives = 300/302 (99.34%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRLSSWKLSAS 1086
            + + +LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRLSSWKLSAS
Sbjct:    2 VRYSKLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRLSSWKLSAS 303
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Planmine SMEST
Match: SMESG000002913.1 (SMESG000002913.1)

HSP 1 Score: 616.305 bits (1588), Expect = 0.000e+0
Identity = 297/302 (98.34%), Postives = 300/302 (99.34%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRLSSWKLSAS 1086
            + + +LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRLSSWKLSAS
Sbjct:   23 VRYSKLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRLSSWKLSAS 324

HSP 2 Score: 59.6918 bits (143), Expect = 1.276e-9
Identity = 27/27 (100.00%), Postives = 27/27 (100.00%), Query Frame = 3 
Query:   69 MSKLLNFKNNDRNDFVSICAPMVRYSK 149
            MSKLLNFKNNDRNDFVSICAPMVRYSK
Sbjct:    1 MSKLLNFKNNDRNDFVSICAPMVRYSK 27
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Planmine SMEST
Match: SMESG000002913.1 (SMESG000002913.1)

HSP 1 Score: 599.742 bits (1545), Expect = 0.000e+0
Identity = 288/296 (97.30%), Postives = 291/296 (98.31%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRLSS 1068
            + + +LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVN   S
Sbjct:    2 VRYSKLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNSFES 297
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Planmine SMEST
Match: SMESG000002913.1 (SMESG000002913.1)

HSP 1 Score: 599.356 bits (1544), Expect = 0.000e+0
Identity = 288/296 (97.30%), Postives = 291/296 (98.31%), Query Frame = 1 
Query:  181 LNFRRLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNRLSS 1068
            + + +LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVN   S
Sbjct:   23 VRYSKLPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDRTLLHSMSSSAGLINIVNSFES 318

HSP 2 Score: 59.6918 bits (143), Expect = 1.290e-9
Identity = 27/27 (100.00%), Postives = 27/27 (100.00%), Query Frame = 3 
Query:   69 MSKLLNFKNNDRNDFVSICAPMVRYSK 149
            MSKLLNFKNNDRNDFVSICAPMVRYSK
Sbjct:    1 MSKLLNFKNNDRNDFVSICAPMVRYSK 27
[Close]
BLAST of tRNA-dihydrouridine synthase vs. Planmine SMEST
Match: SMESG000068111.1 (SMESG000068111.1)

HSP 1 Score: 131.339 bits (329), Expect = 1.748e-33
Identity = 89/270 (32.96%), Postives = 135/270 (50.00%), Query Frame = 1 
Query:  196 LPFRMLVRELGCDLAYTPMIIADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADGVDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNGFSVSAKIRICEGINGTAE-TVELLRRLDRMGVDWVTVHARTAVER---SEPARWKQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANPALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLN 993
            L +R+L R+ G  LAYTPM  A +F++    R     +   DRPLI QF S +P    EA+KL  +  D +DLN GCPQ  A +   G  L  E +LISEM+KT        + EI      V+AKIR       T E TV   + ++  G+  +T+H RT  ++   +  A W  +  +  A  +S  ++ NG+I+   D     + T   GVMSA G L NP +F +   + S ++ A  ++    ++ C IS    H++ +L   L+
Sbjct:   37 LAWRLLARKYGAQLAYTPMFHAANFVRDPSYRKEAMENSPIDRPLIYQFCSNDPAIFTEAAKLAQKHCDAIDLNLGCPQMIAKRGHYGSYLQDEWDLISEMLKT-------CVKEI---KIPVTAKIR----AQSTVELTVTYAKMIESCGISMLTIHGRTRDQKGVNTGLADWAVIKAVKEA--LSIPVIANGNILFYSDIERCIEATGADGVMSAEGQLHNPGIFMSSEPK-SVWEMALDYLVYAKEHPCNISYSRGHVFKLLHHSLH 289
The following BLAST results are available for this feature:
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DUS4L4.901e-7340.14dihydrouridine synthase 4 like [Source:HGNC Symbol... [more]
DUS4L4.901e-7340.14dihydrouridine synthase 4 like [Source:HGNC Symbol... [more]
DUS4L-BCAP297.575e-5343.26DUS4L-BCAP29 readthrough [Source:NCBI gene;Acc:115... [more]
DUS4L-BCAP297.575e-5343.26DUS4L-BCAP29 readthrough [Source:NCBI gene;Acc:115... [more]
DUS4L-BCAP297.575e-5343.26DUS4L-BCAP29 readthrough [Source:NCBI gene;Acc:115... [more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
C45G9.22.611e-5837.07Uncharacterized tRNA-dihydrouridine synthase-like ... [more]
F36A2.21.373e-3329.56pep chromosome:WBcel235:I:8801612:8804697:-1 gene:... [more]
Y37E11B.54.885e-1928.29tRNA-dihydrouridine(47) synthase [NAD(P)(+)] [Sou... [more]
dus-25.223e-1322.26DihydroUridine Synthase two homolog [Source:UniPr... [more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG104952.582e-6235.00gene:FBgn0032750 transcript:FBtr0081150[more]
CG36459.833e-3431.99gene:FBgn0031238 transcript:FBtr0078140[more]
CG36459.833e-3431.99gene:FBgn0031238 transcript:FBtr0078141[more]
CG36459.833e-3431.99gene:FBgn0031238 transcript:FBtr0336989[more]
CG14342.631e-1724.52gene:FBgn0030554 transcript:FBtr0073903[more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dus4l2.348e-7238.70dihydrouridine synthase 4-like (S. cerevisiae) [So... [more]
dus1l4.788e-3330.79dihydrouridine synthase 1-like (S. cerevisiae) [So... [more]
dus21.630e-1726.32dihydrouridine synthase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
dus21.630e-1726.32dihydrouridine synthase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
dus3l7.977e-1626.07dihydrouridine synthase 3-like (S. cerevisiae) [So... [more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dus4l3.601e-7440.83dihydrouridine synthase 4-like [Source:NCBI gene;A... [more]
ubash3b9.403e-3733.22ubiquitin associated and SH3 domain containing B [... [more]
ubash3b1.147e-3633.22ubiquitin associated and SH3 domain containing B [... [more]
ubash3b1.175e-3633.22ubiquitin associated and SH3 domain containing B [... [more]
ubash3b1.766e-3633.22ubiquitin associated and SH3 domain containing B [... [more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dus4l4.687e-7140.14dihydrouridine synthase 4-like (S. cerevisiae) [So... [more]
Dus1l3.286e-3431.10dihydrouridine synthase 1-like (S. cerevisiae) [So... [more]
Dus1l4.045e-3431.10dihydrouridine synthase 1-like (S. cerevisiae) [So... [more]
Dus1l4.045e-3431.10dihydrouridine synthase 1-like (S. cerevisiae) [So... [more]
Dus1l4.045e-3431.10dihydrouridine synthase 1-like (S. cerevisiae) [So... [more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O95620|DUS4L_HUMAN2.353e-7240.14tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-li... [more]
sp|Q32M08|DUS4L_MOUSE7.862e-7140.07tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-li... [more]
sp|Q09504|YQI2_CAEEL3.321e-5737.07Uncharacterized tRNA-dihydrouridine synthase-like ... [more]
sp|Q06063|DUS4_YEAST1.021e-5136.18tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+] OS... [more]
sp|O74553|DUS4_SCHPO1.833e-5136.70tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+] OS... [more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1EEB61.397e-8443.99tRNA-dihydrouridine synthase OS=Helobdella robusta... [more]
A0A1I8GWF91.155e-8043.85tRNA-dihydrouridine synthase OS=Macrostomum lignan... [more]
A0A1I8I9301.443e-7943.19tRNA-dihydrouridine synthase OS=Macrostomum lignan... [more]
A0A5N5SJQ43.076e-7942.67tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-li... [more]
A0A4D5RL374.465e-7941.58Putative trna-dihydrouridine synthase (Fragment) O... [more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
dus4l2.553e-7439.79dihydrouridine synthase 4 like [Source:NCBI gene;A... [more]
dus1l1.908e-3031.46dihydrouridine synthase 1 like [Source:NCBI gene;A... [more]
dus1l3.640e-3031.46dihydrouridine synthase 1 like [Source:NCBI gene;A... [more]
dus24.070e-1922.39dihydrouridine synthase 2 [Source:NCBI gene;Acc:10... [more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
dus3l3.084e-1726.30dihydrouridine synthase 3-like (S. cerevisiae) [So... [more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4
Match NameE-valueIdentityDescription
DUS41.470e-5336.18Dihydrouridine synthase; member of a widespread fa... [more]
DUS11.692e-3034.32Dihydrouridine synthase; member of a widespread fa... [more]
SMM16.925e-1427.93Dihydrouridine synthase; member of a family of dih... [more]
DUS37.502e-724.11Dihydrouridine synthase; member of a widespread fa... [more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO469521.381e-7138.06tRNA-dihydrouridine synthase [Source:UniProtKB/Tr... [more]
EDO342863.743e-4033.46tRNA-dihydrouridine synthase [Source:UniProtKB/Tr... [more]
EDO421551.123e-1823.90tRNA-dihydrouridine(47) synthase [NAD(P)(+)] [Sou... [more]
EDO392411.676e-1725.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dus4l8.603e-7340.14dihydrouridine synthase 4 like [Source:NCBI gene;A... [more]
dus4l2.140e-7240.14dihydrouridine synthase 4 like [Source:NCBI gene;A... [more]
dus1l6.769e-3331.56dihydrouridine synthase 1 like [Source:NCBI gene;A... [more]
dus1l4.769e-3231.56dihydrouridine synthase 1 like [Source:NCBI gene;A... [more]
dus1l8.032e-3231.56dihydrouridine synthase 1 like [Source:NCBI gene;A... [more]
back to top
BLAST of tRNA-dihydrouridine synthase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000002913.10.000e+098.34SMESG000002913.1[more]
SMESG000002913.11.276e-998.34SMESG000002913.1[more]
SMESG000002913.10.000e+097.30SMESG000002913.1[more]
SMESG000002913.11.290e-997.30SMESG000002913.1[more]
SMESG000068111.11.748e-3332.96SMESG000068111.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30000267 ID=SMED30000267|Name=tRNA-dihydrouridine synthase|organism=Schmidtea mediterranea sexual|type=transcript|length=1267bp
AATAATTAAAAAATGGATTTAATGGAATTTTTAATGGAATGAAAACGTTG
TTTAAAATTCTCACTTAAATGAGCAAGCTTTTAAATTTTAAAAATAACGA
TAGAAATGATTTTGTATCGATATGTGCACCAATGGTTCGGTATTCAAAGT
AAAATTAATCAAATTTATTTTATTTACAATTTAAACTTCCGAAGGTTGCC
CTTTCGCATGCTTGTCCGTGAACTTGGATGTGATCTTGCCTACACACCAA
TGATAATTGCAGATTCATTTTTGAAATCTGAAAAAGCTAGATATTCAGAA
TTTTCATCATGCTCCAGTGATCGACCATTAATTGTACAATTTGCAAGTCG
TAACCCGAACGAGTTACTAGAAGCTTCTAAATTGGTTTATGAATCAGCAG
ATGGAGTGGATCTTAATTGTGGTTGTCCACAAAAATGGGCGATTCAAGAA
AAAATCGGATGCAGTTTAATGAAAGAACCTGAGTTAATATCGGAAATGAT
TAAGACCGTTAAACTAGGAATGCCTGATGTAATTAATGAAATTCATTCAA
ATGGATTCTCAGTGTCTGCAAAAATTCGAATTTGCGAAGGAATAAATGGA
ACAGCGGAAACTGTAGAGTTATTACGTCGACTTGATAGAATGGGAGTTGA
TTGGGTGACTGTGCATGCTAGAACTGCCGTAGAGAGAAGCGAACCTGCCA
GATGGAAACAGTTGGGAGAGATTGTATCGGCAGCCAATGTTTCCTGTGGA
CTGGTTGTGAATGGGGATATTATGTCACTGCAGGACGCTAATGAGGCCTT
TCAGGTTACACAATGCCAGGGAGTTATGAGTGCTCGAGGAATTCTTGCTA
ATCCAGCTCTCTTTTCAACCGAATCCTCCAGAATTTCCTCGTTTGATTGC
GCTCGAATGTTTATCGATCTCGGGATTCAATATGGCTGTCAGATTTCTCA
ACTGCATCAGCATCTCTATTGGATGCTTGAAGGAGATCTTAATCGATCGG
ATCGGACGTTGTTGCATTCTATGTCGAGCTCGGCCGGTTTGATCAATATT
GTCAACAGGTTATCCTCATGGAAATTGTCAGCCTCTTGAATTAATGATGA
TGTTCAAGTTTTGAATCGAATTCTCAGGGTCAGATGATCACATAATAAAT
GGTGTAATTCATCCAATGAGATCAATGTTTCCTGGATTTTGATTGGATGG
AATTTCAATTGATTTGATTTGTTGTTTTATTTTGTTCGTTAATAAATTTG
TTTGACTTAAAAAAAAA
back to top

protein sequence of SMED30000267-orf-1

>SMED30000267-orf-1 ID=SMED30000267-orf-1|Name=SMED30000267-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=328bp
MILYRYVHQWFGIQSKINQIYFIYNLNFRRLPFRMLVRELGCDLAYTPMI
IADSFLKSEKARYSEFSSCSSDRPLIVQFASRNPNELLEASKLVYESADG
VDLNCGCPQKWAIQEKIGCSLMKEPELISEMIKTVKLGMPDVINEIHSNG
FSVSAKIRICEGINGTAETVELLRRLDRMGVDWVTVHARTAVERSEPARW
KQLGEIVSAANVSCGLVVNGDIMSLQDANEAFQVTQCQGVMSARGILANP
ALFSTESSRISSFDCARMFIDLGIQYGCQISQLHQHLYWMLEGDLNRSDR
TLLHSMSSSAGLINIVNRLSSWKLSAS*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR001269tRNA_hU_synthase
IPR013785Aldolase_TIM
IPR018517tRNA_hU_synthase_CS
Vocabulary: biological process
TermDefinition
GO:0008033tRNA processing
GO:0055114oxidation-reduction process
GO:0002943tRNA dihydrouridine synthesis
Vocabulary: molecular function
TermDefinition
GO:0050660flavin adenine dinucleotide binding
GO:0017150tRNA dihydrouridine synthase activity
GO:0003824catalytic activity
GO:0016491oxidoreductase activity