Canalicular multispecific organic anion transporter 1

Overview
NameCanalicular multispecific organic anion transporter 1
Smed IDSMED30000258
Length (bp)4827
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Canalicular multispecific organic anion transporter 1 (SMED30000258) t-SNE clustered cells

Violin plots show distribution of expression levels for Canalicular multispecific organic anion transporter 1 (SMED30000258) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Canalicular multispecific organic anion transporter 1 (SMED30000258) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Canalicular multispecific organic anion transporter 1 (SMED30000258) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30000258

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30000258h1SMcG0011053 dd_Smed_v4_6609_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30000258h1SMcG0011053 dd_Smed_v6_6609_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Human
Match: ABCC3 (ATP binding cassette subfamily C member 3 [Source:HGNC Symbol;Acc:HGNC:54])

HSP 1 Score: 748.043 bits (1930), Expect = 0.000e+0
Identity = 390/903 (43.19%), Postives = 564/903 (62.46%), Query Frame = 2 
Query:   47 SLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLY-------PPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVE---VSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            +LC         W   +  +T++PD+T CFQ ++L W+P ++LW++   Y+  L        R+  +  I  S L    +   +L +C + ++   + +       P P  ++ P++  ++ +L   L +    +G+ SSGVL  +W L ++ +I    S+    K      D FR  T    F LV  + IL CF +   F  ++ ++                P+         P PE    FLS+L F W T + I GYR PL  KDL++L+E D    +V  +   W ++ ++  + K            ++  P K+   E E+            + + PSFL+AL  T G  ++++  FK+  DLL+F  PQ+L + I FI NP    W GFL+A  +FL SM++S+I Q YYH  +VTG++ RT ++G+IYRKAL ++++ ++ +TVGEIVNLMSVD+Q+  D+  FL++LW+AP+ I++AIYFLWQ LGPSVLAGVA M+ LIP+NG +  K++  Q KQMK+KD+RIKLM+EIL+GIK+LKLYAWE SF + ++ IR  E ++LR+A YL+  +  TW C+PFLV L T   +     ++VL A KAFVS+SLFNIL  P++MLP +I    QA VSLKRI +FL  +ELD ++VE   +SP     + I  GTF+W +   P L +++++VP+G+LVAVVG VG GK+SL+SAL+GE+ K+ G+V  +GS+ Y+PQQAW +N +LQ+N+LF K L   +Y + +EACAL  DL++LP GDQTEIGEKGINLSGGQ+QR+SLARAVY D  ++LLDDPLSAVDSHV KHIFD VIGP G+L+ KTR+LVTHG+++LP+ D I V+ DG VSE G +  LL+ NGSFA F+  Y
Sbjct:    3 ALCGSGELGSKFWDSNLSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLYL--------RHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRAPAPVFFVTPLVVGVTMLLATLLIQYERLQGVQSSGVLIIFWFLCVVCAIVPFRSKILLAKAEGEISDPFRFTTFYIHFALVLSALILACFREKPPFFSAKNVD----------------PN---------PYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLWSLKEEDRSQMVVQQLLEAWRKQEKQTARHK------------ASAAPGKNASGEDEV------LLGARPRPRKPSFLKALLATFGSSFLISACFKLIQDLLSFINPQLLSILIRFISNPMAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFMDLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVERKTISP--GYAITIHSGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFLCNY 852

HSP 2 Score: 177.563 bits (449), Expect = 4.911e-44
Identity = 104/247 (42.11%), Postives = 142/247 (57.49%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYR 3742
            A IG V+ SVF  Y ++     +  +   Y      ++GAN++LS WT     +  QN  S    LG+Y +LG  Q   +++   A+A G   A++ LH  LL N +R+P SFFDTTP GRILN   KDI  VD  +   I + L +    I ++ VI  S+P F + ++PL  +Y + QRFY  TSRQLKR++S+ RSPIYSHF E++ GAS IRAY  S DF    D   D NQ + YP I+S R
Sbjct:  949 AAIGTVELSVFWDYAKAVGLCTTLAICLLYVGQSAAAIGANVWLSAWTNDAMADSRQNNTS--LRLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHNKIRSPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLESVSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNR 1193

HSP 3 Score: 79.7221 bits (195), Expect = 3.833e-14
Identity = 97/415 (23.37%), Postives = 180/415 (43.37%), Query Frame = 2 
Query: 3494 FLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCD-IMTDENQM----AWYPNIVSYRWL-QFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKS 4711
            F++ L+PL     +A +   +  +Q+K  DS  R  + S   E + G   ++ Y     F+K+ + I   E Q+    A+     ++ W+   +L T+    I L   + V   + + +  A +S+S    +   LN + ++ S+L   +V+++RI+++   E   P ++E       +     +   + +  +   L   L +L+I V  G  + +VG  G GKSSL  AL   +E  EG +              ++  +  +PQ   + + T++ N+      +       LE   L + +     G Q  + E G NLS GQ+Q V LARA+   + + +LD+  +AVD      I   +          T + + H ++ +   D ++VL  G+V E+     LL    S
Sbjct:  458 FMVLLIPLNGA--VAVKMRAFQVKQMKLKDS--RIKLMS---EILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTL----ITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVERKTISPGY----AITIHSGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKV-------------HMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGS 844
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Human
Match: ABCC3 (ATP binding cassette subfamily C member 3 [Source:HGNC Symbol;Acc:HGNC:54])

HSP 1 Score: 748.043 bits (1930), Expect = 0.000e+0
Identity = 390/903 (43.19%), Postives = 564/903 (62.46%), Query Frame = 2 
Query:   47 SLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLY-------PPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVE---VSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            +LC         W   +  +T++PD+T CFQ ++L W+P ++LW++   Y+  L        R+  +  I  S L    +   +L +C + ++   + +       P P  ++ P++  ++ +L   L +    +G+ SSGVL  +W L ++ +I    S+    K      D FR  T    F LV  + IL CF +   F  ++ ++                P+         P PE    FLS+L F W T + I GYR PL  KDL++L+E D    +V  +   W ++ ++  + K            ++  P K+   E E+            + + PSFL+AL  T G  ++++  FK+  DLL+F  PQ+L + I FI NP    W GFL+A  +FL SM++S+I Q YYH  +VTG++ RT ++G+IYRKAL ++++ ++ +TVGEIVNLMSVD+Q+  D+  FL++LW+AP+ I++AIYFLWQ LGPSVLAGVA M+ LIP+NG +  K++  Q KQMK+KD+RIKLM+EIL+GIK+LKLYAWE SF + ++ IR  E ++LR+A YL+  +  TW C+PFLV L T   +     ++VL A KAFVS+SLFNIL  P++MLP +I    QA VSLKRI +FL  +ELD ++VE   +SP     + I  GTF+W +   P L +++++VP+G+LVAVVG VG GK+SL+SAL+GE+ K+ G+V  +GS+ Y+PQQAW +N +LQ+N+LF K L   +Y + +EACAL  DL++LP GDQTEIGEKGINLSGGQ+QR+SLARAVY D  ++LLDDPLSAVDSHV KHIFD VIGP G+L+ KTR+LVTHG+++LP+ D I V+ DG VSE G +  LL+ NGSFA F+  Y
Sbjct:    3 ALCGSGELGSKFWDSNLSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLYL--------RHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRAPAPVFFVTPLVVGVTMLLATLLIQYERLQGVQSSGVLIIFWFLCVVCAIVPFRSKILLAKAEGEISDPFRFTTFYIHFALVLSALILACFREKPPFFSAKNVD----------------PN---------PYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLWSLKEEDRSQMVVQQLLEAWRKQEKQTARHK------------ASAAPGKNASGEDEV------LLGARPRPRKPSFLKALLATFGSSFLISACFKLIQDLLSFINPQLLSILIRFISNPMAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFMDLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVERKTISP--GYAITIHSGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFLCNY 852

HSP 2 Score: 619.002 bits (1595), Expect = 0.000e+0
Identity = 315/582 (54.12%), Postives = 411/582 (70.62%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            A IG V+ SVF  Y ++     +  +   Y      ++GAN++LS WT     +  QN  S    LG+Y +LG  Q   +++   A+A G   A++ LH  LL N +R+P SFFDTTP GRILN   KDI  VD  +   I + L +    I ++ VI  S+P F + ++PL  +Y + QRFY  TSRQLKR++S+ RSPIYSHF E++ GAS IRAY  S DF    D   D NQ + YP I+S RWL   +E +GN V+L + + AV+ RS++  G  GLS+SY+LQ+T  LN+M+RM SDLES+ VAVER+KEY++ E+EAPW +E S+    WP  G VEF NYSVRYRPGLDLVLR+L++ V  GEK+GIVGRTGAGKSS+ L LFR++E A+G I ID  ++  +GLHDLRS++TIIPQDPILFSGT+RMNLDPF  +S+ ++W  LE+S+L +F++    GL +  SEGGENLSVGQ+QLVCLARALL+KS++LVLDEATAA+DLETD+LIQ++IR QF  CTVLTIAHRLNTIMDY RV+VL++G V E DSP NL+A  + IF+ MA DAGLA
Sbjct:  949 AAIGTVELSVFWDYAKAVGLCTTLAICLLYVGQSAAAIGANVWLSAWTNDAMADSRQNNTS--LRLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHNKIRSPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLESVSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNRWLSIGVEFVGNCVVLFAALFAVIGRSSLNPGLVGLSVSYSLQVTFALNWMIRMMSDLESNIVAVERVKEYSKTETEAPWVVEGSRPPEGWPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGSYSEEDIWWALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIA-ARGIFYGMARDAGLA 1527

HSP 3 Score: 79.337 bits (194), Expect = 6.478e-14
Identity = 97/415 (23.37%), Postives = 180/415 (43.37%), Query Frame = 2 
Query: 3494 FLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCD-IMTDENQM----AWYPNIVSYRWL-QFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKS 4711
            F++ L+PL     +A +   +  +Q+K  DS  R  + S   E + G   ++ Y     F+K+ + I   E Q+    A+     ++ W+   +L T+    I L   + V   + + +  A +S+S    +   LN + ++ S+L   +V+++RI+++   E   P ++E       +     +   + +  +   L   L +L+I V  G  + +VG  G GKSSL  AL   +E  EG +              ++  +  +PQ   + + T++ N+      +       LE   L + +     G Q  + E G NLS GQ+Q V LARA+   + + +LD+  +AVD      I   +          T + + H ++ +   D ++VL  G+V E+     LL    S
Sbjct:  458 FMVLLIPLNGA--VAVKMRAFQVKQMKLKDS--RIKLMS---EILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTL----ITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVERKTISPGYA----ITIHSGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKV-------------HMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGS 844

HSP 4 Score: 58.9214 bits (141), Expect = 1.015e-7
Identity = 54/224 (24.11%), Postives = 94/224 (41.96%), Query Frame = 2 
Query: 2090 VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRV---IEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIR 2713
            VL ++++ V  G  V +VG  G+GK+S+   L   L    G +               R  +  IPQ     + +L+ N+    P  ++    +   +E   L   +   PAG   +  E G NLS GQ+Q + LARA+ +   + +LD+  +A+D      I   +        + T + + H L  +    ++ V+  G V+E  +   L+   G F    R
Sbjct: 1305 VLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNL---DPFGSYSEEDIWWALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATI---RTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIAARGIFYGMAR 1522
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Human
Match: ABCC1 (ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51])

HSP 1 Score: 740.339 bits (1910), Expect = 0.000e+0
Identity = 379/896 (42.30%), Postives = 565/896 (63.06%), Query Frame = 2 
Query:   50 LCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDE----KPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
             CS   +D  LW   + WNT +PD T CFQ T+L W+P  +LW +C  +  +  ++    Y      N  K+ L   +      +   +  E    ++  P   + P L  I+ +L  +L +L  +KG+ SSG++  +WL+ L+ ++ ++ S+       D   DLFR +T    F L+ +  +L+CF+D +                   PL S    D        PCPE+  SFLS++TF W+TGL+++GYRQPL   DL++L + DT + +V  +   W +E  + ++   +     ++             EE E   V++          +PS  + L+ T G  ++++  FK  +DL+ F+ PQIL L I F+++     W G+   + LF+ + +++++  QY+H C+V+GMR +TAVIG +YRKAL +++++RK +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+Y LW  LGPSVLAGVA+M+ ++P+N ++  K K  Q   MK KDNRIKLMNEIL+GIK+LKLYAWE +F+  +  IR +E ++L+ + YL+AV   TW C PFLVALCTF  +     +++L A  AFVSL+LFNIL FP+++LP VI   +QA VSLKR+  FL  +EL+ +++E  P  +      + + + TF+W +++ P L  I   +PEG+LVAVVG VG GK+SL+SAL+ E+ KV G V  +GS+ Y+PQQAW +N SL++NILF   L    Y  VI+ACAL  DL++LP+GD+TEIGEKG+NLSGGQKQR+SLARAVY +  +YL DDPLSAVD+HVGKHIF+ VIGP G+L +KTRILVTH ++YLP+VD I VM  G +SE G++ ELL  +G+FAEF+RTY
Sbjct:    6 FCSADGSD-PLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLW-ACFPFYFLYLSRHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRS-------------------PLFSETIHDPN------PCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEW-----NPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTY 869

HSP 2 Score: 634.795 bits (1636), Expect = 0.000e+0
Identity = 312/584 (53.42%), Postives = 433/584 (74.14%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGA---NMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A+ G VK SV+  Y+++     SF  +F   L+MC  V A   N +LS WT+    NGTQ  +     L +YG+LG  Q + +   + A++ G  LAS+ LH  LL +ILR+P SFF+ TP G ++NR  K++DTVD  IP  I++++ +   VIG+  VI +++P   + + PL  +Y+  QRFY+ +SRQLKR++S+ RSP+YSHF E+++G S IRA++  + FI + D+  DENQ A+YP+IV+ RWL   LE +GN ++L + + AV++R ++ +G  GLS+SY+LQ+T  LN++VRM+S++E++ VAVER+KEY+E E EAPW I+E+   S WP  GRVEF NY +RYR  LD VLR++N+ ++ GEK+GIVGRTGAGKSSL L LFR+ E AEG IIID  +I K+GLHDLR KITIIPQDP+LFSG++RMNLDPF+Q+SD E+W+ LE+++LK F++   + L +  +EGGENLSVGQ+QLVCLARALL+K+K+LVLDEATAAVDLETDDLIQS+IR QF+ CTVLTIAHRLNTIMDY RV+VL++G ++E  +P +LL  ++ +F+SMA DAGL
Sbjct:  953 AQTGQVKLSVYWDYMKAIGLFISFLSIF---LFMCNHVSALASNYWLSLWTDDPIVNGTQ--EHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLL-QQRGLFYSMAKDAGL 1530

HSP 3 Score: 79.337 bits (194), Expect = 5.958e-14
Identity = 66/278 (23.74%), Postives = 124/278 (44.60%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            LN +  + S +   +V+++R++ +   E   P +IE      D   +  +   N +  +       L  +   +  G  + +VG+ G GKSSL  AL   ++  EG + I             +  +  +PQ   + + ++R N+    Q  +    SV++   L   +     G +  + E G NLS GQKQ V LARA+   + + + D+  +AVD      I  ++   +   K  T + + H ++ +   D ++V+  G++ E+ S Q LLA +
Sbjct:  596 LNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPV-KDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAI-------------KGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARD 859

HSP 4 Score: 72.0182 bits (175), Expect = 1.016e-11
Identity = 88/377 (23.34%), Postives = 154/377 (40.85%), Query Frame = 2 
Query: 1640 NEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPF-LVALCT--FTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGD-ELDTENVEVSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-------------SIGYIPQQAWCRNASLQDNILFSKPLINHKYNRV---IEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            NE L G+ +++ +  +  F     +++ DE        Y  ++ A  W       V  C   F A     S H L+A    +S+S    ++  ++ L  +        V+++R+ ++   + E   +  E +PP   P    V+  +    + +    VL +IN+ +  G  V +VG  G+GK+SL   L        G ++  G              I  IPQ     + SL+ N+    P   +    V   +E   L + +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G + E G  ++LL+  G F
Sbjct: 1156 NETLLGVSVIRAFEEQERFIHQ-SDLKVDE----NQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNL---DPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTI---RTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLF 1521
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Human
Match: ABCC1 (ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51])

HSP 1 Score: 740.339 bits (1910), Expect = 0.000e+0
Identity = 379/896 (42.30%), Postives = 565/896 (63.06%), Query Frame = 2 
Query:   50 LCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDE----KPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
             CS   +D  LW   + WNT +PD T CFQ T+L W+P  +LW +C  +  +  ++    Y      N  K+ L   +      +   +  E    ++  P   + P L  I+ +L  +L +L  +KG+ SSG++  +WL+ L+ ++ ++ S+       D   DLFR +T    F L+ +  +L+CF+D +                   PL S    D        PCPE+  SFLS++TF W+TGL+++GYRQPL   DL++L + DT + +V  +   W +E  + ++   +     ++             EE E   V++          +PS  + L+ T G  ++++  FK  +DL+ F+ PQIL L I F+++     W G+   + LF+ + +++++  QY+H C+V+GMR +TAVIG +YRKAL +++++RK +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+Y LW  LGPSVLAGVA+M+ ++P+N ++  K K  Q   MK KDNRIKLMNEIL+GIK+LKLYAWE +F+  +  IR +E ++L+ + YL+AV   TW C PFLVALCTF  +     +++L A  AFVSL+LFNIL FP+++LP VI   +QA VSLKR+  FL  +EL+ +++E  P  +      + + + TF+W +++ P L  I   +PEG+LVAVVG VG GK+SL+SAL+ E+ KV G V  +GS+ Y+PQQAW +N SL++NILF   L    Y  VI+ACAL  DL++LP+GD+TEIGEKG+NLSGGQKQR+SLARAVY +  +YL DDPLSAVD+HVGKHIF+ VIGP G+L +KTRILVTH ++YLP+VD I VM  G +SE G++ ELL  +G+FAEF+RTY
Sbjct:    6 FCSADGSD-PLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLW-ACFPFYFLYLSRHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRS-------------------PLFSETIHDPN------PCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEW-----NPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTY 869

HSP 2 Score: 634.795 bits (1636), Expect = 0.000e+0
Identity = 312/584 (53.42%), Postives = 433/584 (74.14%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGA---NMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A+ G VK SV+  Y+++     SF  +F   L+MC  V A   N +LS WT+    NGTQ  +     L +YG+LG  Q + +   + A++ G  LAS+ LH  LL +ILR+P SFF+ TP G ++NR  K++DTVD  IP  I++++ +   VIG+  VI +++P   + + PL  +Y+  QRFY+ +SRQLKR++S+ RSP+YSHF E+++G S IRA++  + FI + D+  DENQ A+YP+IV+ RWL   LE +GN ++L + + AV++R ++ +G  GLS+SY+LQ+T  LN++VRM+S++E++ VAVER+KEY+E E EAPW I+E+   S WP  GRVEF NY +RYR  LD VLR++N+ ++ GEK+GIVGRTGAGKSSL L LFR+ E AEG IIID  +I K+GLHDLR KITIIPQDP+LFSG++RMNLDPF+Q+SD E+W+ LE+++LK F++   + L +  +EGGENLSVGQ+QLVCLARALL+K+K+LVLDEATAAVDLETDDLIQS+IR QF+ CTVLTIAHRLNTIMDY RV+VL++G ++E  +P +LL  ++ +F+SMA DAGL
Sbjct:  953 AQTGQVKLSVYWDYMKAIGLFISFLSIF---LFMCNHVSALASNYWLSLWTDDPIVNGTQ--EHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLL-QQRGLFYSMAKDAGL 1530

HSP 3 Score: 79.337 bits (194), Expect = 5.958e-14
Identity = 66/278 (23.74%), Postives = 124/278 (44.60%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            LN +  + S +   +V+++R++ +   E   P +IE      D   +  +   N +  +       L  +   +  G  + +VG+ G GKSSL  AL   ++  EG + I             +  +  +PQ   + + ++R N+    Q  +    SV++   L   +     G +  + E G NLS GQKQ V LARA+   + + + D+  +AVD      I  ++   +   K  T + + H ++ +   D ++V+  G++ E+ S Q LLA +
Sbjct:  596 LNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPV-KDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAI-------------KGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARD 859

HSP 4 Score: 72.0182 bits (175), Expect = 1.016e-11
Identity = 88/377 (23.34%), Postives = 154/377 (40.85%), Query Frame = 2 
Query: 1640 NEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPF-LVALCT--FTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGD-ELDTENVEVSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-------------SIGYIPQQAWCRNASLQDNILFSKPLINHKYNRV---IEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            NE L G+ +++ +  +  F     +++ DE        Y  ++ A  W       V  C   F A     S H L+A    +S+S    ++  ++ L  +        V+++R+ ++   + E   +  E +PP   P    V+  +    + +    VL +IN+ +  G  V +VG  G+GK+SL   L        G ++  G              I  IPQ     + SL+ N+    P   +    V   +E   L + +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G + E G  ++LL+  G F
Sbjct: 1156 NETLLGVSVIRAFEEQERFIHQ-SDLKVDE----NQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNL---DPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTI---RTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLF 1521
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Human
Match: ABCC1 (ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51])

HSP 1 Score: 706.057 bits (1821), Expect = 0.000e+0
Identity = 347/775 (44.77%), Postives = 512/775 (66.06%), Query Frame = 2 
Query:  413 RLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDE----KPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            +L  +KG+ SSG++  +WL+ L+ ++ ++ S+       D   DLFR +T    F L+ +  +L+CF+D +                   PL S    D        PCPE+  SFLS++TF W+TGL+++GYRQPL   DL++L + DT + +V  +   W +E  + ++   +     ++             EE E   V++          +PS  + L+ T G  ++++  FK  +DL+ F+ PQIL L I F+++     W G+   + LF+ + +++++  QY+H C+V+GMR +TAVIG +YRKAL +++++RK +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+Y LW  LGPSVLAGVA+M+ ++P+N ++  K K  Q   MK KDNRIKLMNEIL+GIK+LKLYAWE +F+  +  IR +E ++L+ + YL+AV   TW C PFLVALCTF  +     +++L A  AFVSL+LFNIL FP+++LP VI   +QA VSLKR+  FL  +EL+ +++E  P  +      + + + TF+W +++ P L  I   +PEG+LVAVVG VG GK+SL+SAL+ E+ KV G V  +GS+ Y+PQQAW +N SL++NILF   L    Y  VI+ACAL  DL++LP+GD+TEIGEKG+NLSGGQKQR+SLARAVY +  +YL DDPLSAVD+HVGKHIF+ VIGP G+L +KTRILVTH ++YLP+VD I VM  G +SE G++ ELL  +G+FAEF+RTY
Sbjct:   24 QLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRS-------------------PLFSETIHDPN------PCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEW-----NPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTY 768

HSP 2 Score: 635.565 bits (1638), Expect = 0.000e+0
Identity = 312/584 (53.42%), Postives = 433/584 (74.14%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGA---NMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A+ G VK SV+  Y+++     SF  +F   L+MC  V A   N +LS WT+    NGTQ  +     L +YG+LG  Q + +   + A++ G  LAS+ LH  LL +ILR+P SFF+ TP G ++NR  K++DTVD  IP  I++++ +   VIG+  VI +++P   + + PL  +Y+  QRFY+ +SRQLKR++S+ RSP+YSHF E+++G S IRA++  + FI + D+  DENQ A+YP+IV+ RWL   LE +GN ++L + + AV++R ++ +G  GLS+SY+LQ+T  LN++VRM+S++E++ VAVER+KEY+E E EAPW I+E+   S WP  GRVEF NY +RYR  LD VLR++N+ ++ GEK+GIVGRTGAGKSSL L LFR+ E AEG IIID  +I K+GLHDLR KITIIPQDP+LFSG++RMNLDPF+Q+SD E+W+ LE+++LK F++   + L +  +EGGENLSVGQ+QLVCLARALL+K+K+LVLDEATAAVDLETDDLIQS+IR QF+ CTVLTIAHRLNTIMDY RV+VL++G ++E  +P +LL  ++ +F+SMA DAGL
Sbjct:  862 AQTGQVKLSVYWDYMKAIGLFISFLSIF---LFMCNHVSALASNYWLSLWTDDPIVNGTQ--EHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLL-QQRGLFYSMAKDAGL 1439

HSP 3 Score: 77.7962 bits (190), Expect = 1.585e-13
Identity = 66/278 (23.74%), Postives = 124/278 (44.60%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            LN +  + S +   +V+++R++ +   E   P +IE      D   +  +   N +  +       L  +   +  G  + +VG+ G GKSSL  AL   ++  EG + I             +  +  +PQ   + + ++R N+    Q  +    SV++   L   +     G +  + E G NLS GQKQ V LARA+   + + + D+  +AVD      I  ++   +   K  T + + H ++ +   D ++V+  G++ E+ S Q LLA +
Sbjct:  495 LNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPV-KDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAI-------------KGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARD 758

HSP 4 Score: 71.2478 bits (173), Expect = 1.965e-11
Identity = 88/377 (23.34%), Postives = 154/377 (40.85%), Query Frame = 2 
Query: 1640 NEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPF-LVALCT--FTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGD-ELDTENVEVSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-------------SIGYIPQQAWCRNASLQDNILFSKPLINHKYNRV---IEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            NE L G+ +++ +  +  F     +++ DE        Y  ++ A  W       V  C   F A     S H L+A    +S+S    ++  ++ L  +        V+++R+ ++   + E   +  E +PP   P    V+  +    + +    VL +IN+ +  G  V +VG  G+GK+SL   L        G ++  G              I  IPQ     + SL+ N+    P   +    V   +E   L + +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G + E G  ++LL+  G F
Sbjct: 1065 NETLLGVSVIRAFEEQERFIHQ-SDLKVDE----NQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNL---DPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTI---RTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLF 1430
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Celegans
Match: mrp-1 (pep chromosome:WBcel235:X:576318:587483:-1 gene:WBGene00003407.1 transcript:F57C12.5c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mrp-1)

HSP 1 Score: 594.734 bits (1532), Expect = 0.000e+0
Identity = 343/888 (38.63%), Postives = 508/888 (57.21%), Query Frame = 2 
Query:   86 YDLI--GW--NTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLL--NFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIY-----KKGIHSSGVLFFYWLLQLLASITVI--YSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEK--QNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTL-SSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWG-KTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIG-PSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            Y+L+  GW  N+  P +T C Q+T  + IP LFL    +I+ PIL+ +   +Y++R  +    S +   I+F  LL  +  AT+      L+    LY              +   L+       +GI +SGV+  YWLL ++  +  +  Y   R  K ++    R     F ++   +   L+CFAD                           P +  I  N   CPE   SFL++LTF W +GL   G ++ L  +DL+ L E D  + I+ +       EN   +   +R+K++K  +     N+                            PS L  +F T  +  +  G +K+ +DLL F  P++L   I+FI++ N  +W G  +A+ +FL S+++S+I  QY+H  +  GM  R+ +   +Y K L LS+ +RK  T G IVNLMSVD Q++QD+ +F+ + W+AP+ I++++YFLW+ LG SVLAG  ++I LIP N  I  K++  Q +QMK KD RIK+M+EIL+G+K+LKLY+WE S E+ +  +R  E R+L+  +YLNA + ++W CAPFLVA+ TF  + L    ++VLT    FV+L+LFNIL FP+++   V    +Q   S  R+ +F   +E+  +        +  +K+  G+F+WG K E   L +I   +  G LVA+VG VGSGK+SL+ AL+GE+ K+SG V   GS+ Y+PQ AW +N SL++NILF++P     Y  VIE CAL +DL+ LPA D+TEIGEKGINLSGGQKQR+SLARAVYQ+  + LLDDPLSAVDSHVGKHIF+ VI   +G L +KTR+L+THGLTYL   D++ V+KD  +SE GT+ EL+ +NG+
Sbjct:   14 YELLETGWRNNSNIPQVTNCGQHTDFSTIPTLFL----VIFSPILFYE---LYKSRNSYLRSFSAISLRIIFCCLLVVDLTATVIYDFYLLFTKSPLYNAIHFYGDLVQYAGFCLALVLTIACRNRGIITSGVITLYWLLVVVCGVPELRYYITGRLYKEYEIHSCRAALYVFAYVCSALELFLSCFAD--------------------------TPSNGYIGKN--SCPEYTASFLNQLTFQWFSGLAYLGNKKSLEKEDLWDLNERDKAENIIPSF-----IENLIPEVEGYRRKIKKNPEAAIPKNH----------------------------PSILIPIFKTYKFTLLAGGCYKLMFDLLQFVAPELLRQLISFIEDKNQPMWIGVSIALLMFLSSLLQSMILHQYFHEMFRLGMNIRSVLTSAVYTKTLNLSNEARKGKTTGAIVNLMSVDIQRIQDMTTFIMLFWSAPLQILLSLYFLWKLLGVSVLAGFVILILLIPFNSFISVKMRNCQMEQMKFKDERIKMMSEILNGMKVLKLYSWEKSMEKMVLEVREKEIRVLKKLSYLNAATTLSWACAPFLVAVLTFGLYVLWDPENNVLTPQITFVALALFNILRFPLAVFAMVFSQAVQCSASNTRLKEFFAAEEMSPQTSIAYGGTDSAIKMDGGSFAWGSKEEDRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLSGSVQVNGSVAYVPQLAWIQNLSLRNNILFNRPYDAKLYQNVIENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKHIFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELMNSNGA 833

HSP 2 Score: 585.489 bits (1508), Expect = 0.000e+0
Identity = 305/585 (52.14%), Postives = 400/585 (68.38%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETG---STNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIG--SGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            E G VKF V++SY R+     +      Y       V +N++L+ W++     + +G  +       LGIY  LG GQA  +   +  +A G   AS+ LH  LL+NI+R+P +FFD TPLGRILNR GKDI+ +D ++P +IR  +MT   VI ++FVI  ++P+  +  + L  +Y++  RFY+ TSRQLKR++S  RSPIYSHFQESI GASSIRAY V D FI++     DEN   +YP+IV+ RWL   LE +GNL++L S   AV  R + G  +G  GLS+SYAL IT  LN+ VRMTS+LE++ VAVERI EY    +E   N  +S A   WP++G +   N+SVRYRPGLDLVL  +   +   EK+GIVGRTGAGKSSL LALFR+IE   G I ID  +I  L L  LRS++TI+PQDP+LFSGT+RMNLDPF   SD ++W  L  ++L SF+    EGL + +SEGGENLSVGQ+QL+CLARALL+K+KVLVLDEA AAVD+ETD L+Q +IR QFK CTVLTIAHRLNT+MD DR++VL++G V E D+P+ LL+N   IF+SMA DA +
Sbjct:  951 ETGKVKFEVYMSYFRAIGIKIALVFFLVYVASSMLGVFSNLYLARWSDDAKEIALSGNGSSSETQIRLGIYAVLGMGQATSVCAASIIMALGMVCASRLLHATLLENIMRSPMAFFDVTPLGRILNRFGKDIEAIDQTLPHSIRAMVMTIFNVISTVFVIIWATPWAGIGFLVLGFVYFVVLRFYVSTSRQLKRLESASRSPIYSHFQESIQGASSIRAYGVVDKFIRESQHRVDENLATYYPSIVANRWLAVRLEMVGNLIVLSSAGAAVYFRDSPGLSAGLVGLSVSYALNITQTLNWAVRMTSELETNIVAVERINEYTITPTEG--NNSQSLAPKSWPENGEISIKNFSVRYRPGLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNLDPFFAFSDDQIWEALRNAHLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQFKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSNPDGIFYSMAKDANV 1533

HSP 3 Score: 71.633 bits (174), Expect = 5.331e-12
Identity = 58/214 (27.10%), Postives = 105/214 (49.07%), Query Frame = 2 
Query: 4070 DLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELW-SVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKC----TVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            D  L ++   +  G+ + IVGR G+GKSSL  AL   +    G++ ++               +  +PQ   + + ++R N+  FN+  D +L+ +V+E   L   +       +  + E G NLS GQKQ V LARA+ + +++++LD+  +AVD      I  ++      C    T + + H L  +   D+V+VL+   + E+ + Q L+
Sbjct:  629 DRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLSGSVQVNG-------------SVAYVPQLAWIQNLSLRNNI-LFNRPYDAKLYQNVIENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKHIFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELM 828

HSP 4 Score: 67.0106 bits (162), Expect = 1.229e-10
Identity = 67/267 (25.09%), Postives = 117/267 (43.82%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVEVSP---PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALI------GELYKVSGRVMC-------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEA---CALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAV----DSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKN 2686
            V+++RIN++ +       +  ++P   P+   + I + +  +      VL  +   +     + +VG  G+GK+SL  AL       G   ++ G  +        R  +  +PQ     + +++ N+    P      +++ EA     L   +K L  G    I E G NLS GQ+Q I LARA+ +   V +LD+  +AV    DS + K I +Q           T + + H L  +   D++ V+  G V+E  T  +LL N
Sbjct: 1263 VAVERINEYTITPTEGNNSQSLAPKSWPENGEISIKNFSVRYRPGLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNL---DPFFAFSDDQIWEALRNAHLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQ-------FKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSN 1519
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Celegans
Match: mrp-1 (pep chromosome:WBcel235:X:576318:587483:-1 gene:WBGene00003407.1 transcript:F57C12.5a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mrp-1)

HSP 1 Score: 594.734 bits (1532), Expect = 0.000e+0
Identity = 343/888 (38.63%), Postives = 508/888 (57.21%), Query Frame = 2 
Query:   86 YDLI--GW--NTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLL--NFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIY-----KKGIHSSGVLFFYWLLQLLASITVI--YSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEK--QNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTL-SSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWG-KTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIG-PSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            Y+L+  GW  N+  P +T C Q+T  + IP LFL    +I+ PIL+ +   +Y++R  +    S +   I+F  LL  +  AT+      L+    LY              +   L+       +GI +SGV+  YWLL ++  +  +  Y   R  K ++    R     F ++   +   L+CFAD                           P +  I  N   CPE   SFL++LTF W +GL   G ++ L  +DL+ L E D  + I+ +       EN   +   +R+K++K  +     N+                            PS L  +F T  +  +  G +K+ +DLL F  P++L   I+FI++ N  +W G  +A+ +FL S+++S+I  QY+H  +  GM  R+ +   +Y K L LS+ +RK  T G IVNLMSVD Q++QD+ +F+ + W+AP+ I++++YFLW+ LG SVLAG  ++I LIP N  I  K++  Q +QMK KD RIK+M+EIL+G+K+LKLY+WE S E+ +  +R  E R+L+  +YLNA + ++W CAPFLVA+ TF  + L    ++VLT    FV+L+LFNIL FP+++   V    +Q   S  R+ +F   +E+  +        +  +K+  G+F+WG K E   L +I   +  G LVA+VG VGSGK+SL+ AL+GE+ K+SG V   GS+ Y+PQ AW +N SL++NILF++P     Y  VIE CAL +DL+ LPA D+TEIGEKGINLSGGQKQR+SLARAVYQ+  + LLDDPLSAVDSHVGKHIF+ VI   +G L +KTR+L+THGLTYL   D++ V+KD  +SE GT+ EL+ +NG+
Sbjct:   14 YELLETGWRNNSNIPQVTNCGQHTDFSTIPTLFL----VIFSPILFYE---LYKSRNSYLRSFSAISLRIIFCCLLVVDLTATVIYDFYLLFTKSPLYNAIHFYGDLVQYAGFCLALVLTIACRNRGIITSGVITLYWLLVVVCGVPELRYYITGRLYKEYEIHSCRAALYVFAYVCSALELFLSCFAD--------------------------TPSNGYIGKN--SCPEYTASFLNQLTFQWFSGLAYLGNKKSLEKEDLWDLNERDKAENIIPSF-----IENLIPEVEGYRRKIKKNPEAAIPKNH----------------------------PSILIPIFKTYKFTLLAGGCYKLMFDLLQFVAPELLRQLISFIEDKNQPMWIGVSIALLMFLSSLLQSMILHQYFHEMFRLGMNIRSVLTSAVYTKTLNLSNEARKGKTTGAIVNLMSVDIQRIQDMTTFIMLFWSAPLQILLSLYFLWKLLGVSVLAGFVILILLIPFNSFISVKMRNCQMEQMKFKDERIKMMSEILNGMKVLKLYSWEKSMEKMVLEVREKEIRVLKKLSYLNAATTLSWACAPFLVAVLTFGLYVLWDPENNVLTPQITFVALALFNILRFPLAVFAMVFSQAVQCSASNTRLKEFFAAEEMSPQTSIAYGGTDSAIKMDGGSFAWGSKEEDRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLSGSVQVNGSVAYVPQLAWIQNLSLRNNILFNRPYDAKLYQNVIENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKHIFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELMNSNGA 833

HSP 2 Score: 581.637 bits (1498), Expect = 5.522e-180
Identity = 305/585 (52.14%), Postives = 394/585 (67.35%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETG---STNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIG--SGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            E G VKF V++SY R+     +      Y       V +N++L+ W++     + +G  +       LGIY  LG GQA  +   +  +A G   AS+ LH  LL+NI+R+P +FFD TPLGRILNR GKD+D VD  IP T+ +++ TA   I  I +I  ++P  +  L+PL        RFY+ TSRQLKR++S  RSPIYSHFQESI GASSIRAY V D FI++     DEN   +YP+IV+ RWL   LE +GNL++L S   AV  R + G  +G  GLS+SYAL IT  LN+ VRMTS+LE++ VAVERI EY    +E   N  +S A   WP++G +   N+SVRYRPGLDLVL  +   +   EK+GIVGRTGAGKSSL LALFR+IE   G I ID  +I  L L  LRS++TI+PQDP+LFSGT+RMNLDPF   SD ++W  L  ++L SF+    EGL + +SEGGENLSVGQ+QL+CLARALL+K+KVLVLDEA AAVD+ETD L+Q +IR QFK CTVLTIAHRLNT+MD DR++VL++G V E D+P+ LL+N   IF+SMA DA +
Sbjct:  951 ETGKVKFEVYMSYFRAIGIKIALVFFLVYVASSMLGVFSNLYLARWSDDAKEIALSGNGSSSETQIRLGIYAVLGMGQATSVCAASIIMALGMVCASRLLHATLLENIMRSPMAFFDVTPLGRILNRFGKDVDGVDTDIPRTMSMFIRTAVSSIEIIAIILWATPLAISLLLPLFI------RFYVSTSRQLKRLESASRSPIYSHFQESIQGASSIRAYGVVDKFIRESQHRVDENLATYYPSIVANRWLAVRLEMVGNLIVLSSAGAAVYFRDSPGLSAGLVGLSVSYALNITQTLNWAVRMTSELETNIVAVERINEYTITPTEG--NNSQSLAPKSWPENGEISIKNFSVRYRPGLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNLDPFFAFSDDQIWEALRNAHLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQFKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSNPDGIFYSMAKDANV 1527

HSP 3 Score: 71.2478 bits (173), Expect = 6.467e-12
Identity = 58/214 (27.10%), Postives = 105/214 (49.07%), Query Frame = 2 
Query: 4070 DLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELW-SVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKC----TVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            D  L ++   +  G+ + IVGR G+GKSSL  AL   +    G++ ++               +  +PQ   + + ++R N+  FN+  D +L+ +V+E   L   +       +  + E G NLS GQKQ V LARA+ + +++++LD+  +AVD      I  ++      C    T + + H L  +   D+V+VL+   + E+ + Q L+
Sbjct:  629 DRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLSGSVQVNG-------------SVAYVPQLAWIQNLSLRNNI-LFNRPYDAKLYQNVIENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKHIFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELM 828

HSP 4 Score: 67.0106 bits (162), Expect = 1.430e-10
Identity = 67/267 (25.09%), Postives = 117/267 (43.82%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVEVSP---PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALI------GELYKVSGRVMC-------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEA---CALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAV----DSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKN 2686
            V+++RIN++ +       +  ++P   P+   + I + +  +      VL  +   +     + +VG  G+GK+SL  AL       G   ++ G  +        R  +  +PQ     + +++ N+    P      +++ EA     L   +K L  G    I E G NLS GQ+Q I LARA+ +   V +LD+  +AV    DS + K I +Q           T + + H L  +   D++ V+  G V+E  T  +LL N
Sbjct: 1257 VAVERINEYTITPTEGNNSQSLAPKSWPENGEISIKNFSVRYRPGLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNL---DPFFAFSDDQIWEALRNAHLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQ-------FKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSN 1513
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Celegans
Match: mrp-1 (pep chromosome:WBcel235:X:576318:587483:-1 gene:WBGene00003407.1 transcript:F57C12.5e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mrp-1)

HSP 1 Score: 593.964 bits (1530), Expect = 0.000e+0
Identity = 343/888 (38.63%), Postives = 508/888 (57.21%), Query Frame = 2 
Query:   86 YDLI--GW--NTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLL--NFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIY-----KKGIHSSGVLFFYWLLQLLASITVI--YSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEK--QNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTL-SSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWG-KTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIG-PSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            Y+L+  GW  N+  P +T C Q+T  + IP LFL    +I+ PIL+ +   +Y++R  +    S +   I+F  LL  +  AT+      L+    LY              +   L+       +GI +SGV+  YWLL ++  +  +  Y   R  K ++    R     F ++   +   L+CFAD                           P +  I  N   CPE   SFL++LTF W +GL   G ++ L  +DL+ L E D  + I+ +       EN   +   +R+K++K  +     N+                            PS L  +F T  +  +  G +K+ +DLL F  P++L   I+FI++ N  +W G  +A+ +FL S+++S+I  QY+H  +  GM  R+ +   +Y K L LS+ +RK  T G IVNLMSVD Q++QD+ +F+ + W+AP+ I++++YFLW+ LG SVLAG  ++I LIP N  I  K++  Q +QMK KD RIK+M+EIL+G+K+LKLY+WE S E+ +  +R  E R+L+  +YLNA + ++W CAPFLVA+ TF  + L    ++VLT    FV+L+LFNIL FP+++   V    +Q   S  R+ +F   +E+  +        +  +K+  G+F+WG K E   L +I   +  G LVA+VG VGSGK+SL+ AL+GE+ K+SG V   GS+ Y+PQ AW +N SL++NILF++P     Y  VIE CAL +DL+ LPA D+TEIGEKGINLSGGQKQR+SLARAVYQ+  + LLDDPLSAVDSHVGKHIF+ VI   +G L +KTR+L+THGLTYL   D++ V+KD  +SE GT+ EL+ +NG+
Sbjct:   14 YELLETGWRNNSNIPQVTNCGQHTDFSTIPTLFL----VIFSPILFYE---LYKSRNSYLRSFSAISLRIIFCCLLVVDLTATVIYDFYLLFTKSPLYNAIHFYGDLVQYAGFCLALVLTIACRNRGIITSGVITLYWLLVVVCGVPELRYYITGRLYKEYEIHSCRAALYVFAYVCSALELFLSCFAD--------------------------TPSNGYIGKN--SCPEYTASFLNQLTFQWFSGLAYLGNKKSLEKEDLWDLNERDKAENIIPSF-----IENLIPEVEGYRRKIKKNPEAAIPKNH----------------------------PSILIPIFKTYKFTLLAGGCYKLMFDLLQFVAPELLRQLISFIEDKNQPMWIGVSIALLMFLSSLLQSMILHQYFHEMFRLGMNIRSVLTSAVYTKTLNLSNEARKGKTTGAIVNLMSVDIQRIQDMTTFIMLFWSAPLQILLSLYFLWKLLGVSVLAGFVILILLIPFNSFISVKMRNCQMEQMKFKDERIKMMSEILNGMKVLKLYSWEKSMEKMVLEVREKEIRVLKKLSYLNAATTLSWACAPFLVAVLTFGLYVLWDPENNVLTPQITFVALALFNILRFPLAVFAMVFSQAVQCSASNTRLKEFFAAEEMSPQTSIAYGGTDSAIKMDGGSFAWGSKEEDRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLSGSVQVNGSVAYVPQLAWIQNLSLRNNILFNRPYDAKLYQNVIENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKHIFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELMNSNGA 833

HSP 2 Score: 579.326 bits (1492), Expect = 4.183e-179
Identity = 301/585 (51.45%), Postives = 394/585 (67.35%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETG---STNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIG--SGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            E G VKF V++SY R+     +      Y       V +N++L+ W++     + +G  +       LGIY  LG GQA  +   +  +A G   AS+ LH  LL+NI+R+P +FFD TPLGRILNR GKD+D VD  +P  I  +L+T S ++  +   S ++P+ +  +V +    +   RFY+ TSRQLKR++S  RSPIYSHFQESI GASSIRAY V D FI++     DEN   +YP+IV+ RWL   LE +GNL++L S   AV  R + G  +G  GLS+SYAL IT  LN+ VRMTS+LE++ VAVERI EY    +E   N  +S A   WP++G +   N+SVRYRPGLDLVL  +   +   EK+GIVGRTGAGKSSL LALFR+IE   G I ID  +I  L L  LRS++TI+PQDP+LFSGT+RMNLDPF   SD ++W  L  ++L SF+    EGL + +SEGGENLSVGQ+QL+CLARALL+K+KVLVLDEA AAVD+ETD L+Q +IR QFK CTVLTIAHRLNT+MD DR++VL++G V E D+P+ LL+N   IF+SMA DA +
Sbjct:  951 ETGKVKFEVYMSYFRAIGIKIALVFFLVYVASSMLGVFSNLYLARWSDDAKEIALSGNGSSSETQIRLGIYAVLGMGQATSVCAASIIMALGMVCASRLLHATLLENIMRSPMAFFDVTPLGRILNRFGKDMDVVDERLPDNIGDFLLTFSELVACVVFTSYATPFAIFPIVLIAIGCFAILRFYVSTSRQLKRLESASRSPIYSHFQESIQGASSIRAYGVVDKFIRESQHRVDENLATYYPSIVANRWLAVRLEMVGNLIVLSSAGAAVYFRDSPGLSAGLVGLSVSYALNITQTLNWAVRMTSELETNIVAVERINEYTITPTEG--NNSQSLAPKSWPENGEISIKNFSVRYRPGLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNLDPFFAFSDDQIWEALRNAHLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQFKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSNPDGIFYSMAKDANV 1533

HSP 3 Score: 71.2478 bits (173), Expect = 6.102e-12
Identity = 58/214 (27.10%), Postives = 105/214 (49.07%), Query Frame = 2 
Query: 4070 DLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELW-SVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKC----TVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            D  L ++   +  G+ + IVGR G+GKSSL  AL   +    G++ ++               +  +PQ   + + ++R N+  FN+  D +L+ +V+E   L   +       +  + E G NLS GQKQ V LARA+ + +++++LD+  +AVD      I  ++      C    T + + H L  +   D+V+VL+   + E+ + Q L+
Sbjct:  629 DRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLSGSVQVNG-------------SVAYVPQLAWIQNLSLRNNI-LFNRPYDAKLYQNVIENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKHIFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELM 828

HSP 4 Score: 67.0106 bits (162), Expect = 1.395e-10
Identity = 67/267 (25.09%), Postives = 117/267 (43.82%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVEVSP---PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALI------GELYKVSGRVMC-------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEA---CALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAV----DSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKN 2686
            V+++RIN++ +       +  ++P   P+   + I + +  +      VL  +   +     + +VG  G+GK+SL  AL       G   ++ G  +        R  +  +PQ     + +++ N+    P      +++ EA     L   +K L  G    I E G NLS GQ+Q I LARA+ +   V +LD+  +AV    DS + K I +Q           T + + H L  +   D++ V+  G V+E  T  +LL N
Sbjct: 1263 VAVERINEYTITPTEGNNSQSLAPKSWPENGEISIKNFSVRYRPGLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNL---DPFFAFSDDQIWEALRNAHLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQ-------FKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSN 1519
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Celegans
Match: mrp-1 (pep chromosome:WBcel235:X:576318:587483:-1 gene:WBGene00003407.1 transcript:F57C12.5d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mrp-1)

HSP 1 Score: 593.964 bits (1530), Expect = 0.000e+0
Identity = 343/888 (38.63%), Postives = 508/888 (57.21%), Query Frame = 2 
Query:   86 YDLI--GW--NTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLL--NFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIY-----KKGIHSSGVLFFYWLLQLLASITVI--YSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEK--QNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTL-SSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWG-KTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIG-PSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            Y+L+  GW  N+  P +T C Q+T  + IP LFL    +I+ PIL+ +   +Y++R  +    S +   I+F  LL  +  AT+      L+    LY              +   L+       +GI +SGV+  YWLL ++  +  +  Y   R  K ++    R     F ++   +   L+CFAD                           P +  I  N   CPE   SFL++LTF W +GL   G ++ L  +DL+ L E D  + I+ +       EN   +   +R+K++K  +     N+                            PS L  +F T  +  +  G +K+ +DLL F  P++L   I+FI++ N  +W G  +A+ +FL S+++S+I  QY+H  +  GM  R+ +   +Y K L LS+ +RK  T G IVNLMSVD Q++QD+ +F+ + W+AP+ I++++YFLW+ LG SVLAG  ++I LIP N  I  K++  Q +QMK KD RIK+M+EIL+G+K+LKLY+WE S E+ +  +R  E R+L+  +YLNA + ++W CAPFLVA+ TF  + L    ++VLT    FV+L+LFNIL FP+++   V    +Q   S  R+ +F   +E+  +        +  +K+  G+F+WG K E   L +I   +  G LVA+VG VGSGK+SL+ AL+GE+ K+SG V   GS+ Y+PQ AW +N SL++NILF++P     Y  VIE CAL +DL+ LPA D+TEIGEKGINLSGGQKQR+SLARAVYQ+  + LLDDPLSAVDSHVGKHIF+ VI   +G L +KTR+L+THGLTYL   D++ V+KD  +SE GT+ EL+ +NG+
Sbjct:   14 YELLETGWRNNSNIPQVTNCGQHTDFSTIPTLFL----VIFSPILFYE---LYKSRNSYLRSFSAISLRIIFCCLLVVDLTATVIYDFYLLFTKSPLYNAIHFYGDLVQYAGFCLALVLTIACRNRGIITSGVITLYWLLVVVCGVPELRYYITGRLYKEYEIHSCRAALYVFAYVCSALELFLSCFAD--------------------------TPSNGYIGKN--SCPEYTASFLNQLTFQWFSGLAYLGNKKSLEKEDLWDLNERDKAENIIPSF-----IENLIPEVEGYRRKIKKNPEAAIPKNH----------------------------PSILIPIFKTYKFTLLAGGCYKLMFDLLQFVAPELLRQLISFIEDKNQPMWIGVSIALLMFLSSLLQSMILHQYFHEMFRLGMNIRSVLTSAVYTKTLNLSNEARKGKTTGAIVNLMSVDIQRIQDMTTFIMLFWSAPLQILLSLYFLWKLLGVSVLAGFVILILLIPFNSFISVKMRNCQMEQMKFKDERIKMMSEILNGMKVLKLYSWEKSMEKMVLEVREKEIRVLKKLSYLNAATTLSWACAPFLVAVLTFGLYVLWDPENNVLTPQITFVALALFNILRFPLAVFAMVFSQAVQCSASNTRLKEFFAAEEMSPQTSIAYGGTDSAIKMDGGSFAWGSKEEDRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLSGSVQVNGSVAYVPQLAWIQNLSLRNNILFNRPYDAKLYQNVIENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKHIFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELMNSNGA 833

HSP 2 Score: 590.882 bits (1522), Expect = 0.000e+0
Identity = 306/585 (52.31%), Postives = 398/585 (68.03%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETG---STNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIG--SGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            E G VKF V++SY R+     +      Y       V +N++L+ W++     + +G  +       LGIY  LG GQA  +   +  +A G   AS+ LH  LL+NI+R+P +FFD TPLGRILNR GKD+D VD  IP T+ +++ TA   I  I +I  ++P  +  L+PL  +Y++  RFY+ TSRQLKR++S  RSPIYSHFQESI GASSIRAY V D FI++     DEN   +YP+IV+ RWL   LE +GNL++L S   AV  R + G  +G  GLS+SYAL IT  LN+ VRMTS+LE++ VAVERI EY    +E   N  +S A   WP++G +   N+SVRYRPGLDLVL  +   +   EK+GIVGRTGAGKSSL LALFR+IE   G I ID  +I  L L  LRS++TI+PQDP+LFSGT+RMNLDPF   SD ++W  L  ++L SF+    EGL + +SEGGENLSVGQ+QL+CLARALL+K+KVLVLDEA AAVD+ETD L+Q +IR QFK CTVLTIAHRLNT+MD DR++VL++G V E D+P+ LL+N   IF+SMA DA +
Sbjct:  951 ETGKVKFEVYMSYFRAIGIKIALVFFLVYVASSMLGVFSNLYLARWSDDAKEIALSGNGSSSETQIRLGIYAVLGMGQATSVCAASIIMALGMVCASRLLHATLLENIMRSPMAFFDVTPLGRILNRFGKDVDGVDTDIPRTMSMFIRTAVSSIEIIAIILWATPLAISLLLPLFIVYFVVLRFYVSTSRQLKRLESASRSPIYSHFQESIQGASSIRAYGVVDKFIRESQHRVDENLATYYPSIVANRWLAVRLEMVGNLIVLSSAGAAVYFRDSPGLSAGLVGLSVSYALNITQTLNWAVRMTSELETNIVAVERINEYTITPTEG--NNSQSLAPKSWPENGEISIKNFSVRYRPGLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNLDPFFAFSDDQIWEALRNAHLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQFKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSNPDGIFYSMAKDANV 1533

HSP 3 Score: 71.2478 bits (173), Expect = 6.867e-12
Identity = 58/214 (27.10%), Postives = 105/214 (49.07%), Query Frame = 2 
Query: 4070 DLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELW-SVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKC----TVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            D  L ++   +  G+ + IVGR G+GKSSL  AL   +    G++ ++               +  +PQ   + + ++R N+  FN+  D +L+ +V+E   L   +       +  + E G NLS GQKQ V LARA+ + +++++LD+  +AVD      I  ++      C    T + + H L  +   D+V+VL+   + E+ + Q L+
Sbjct:  629 DRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLSGSVQVNG-------------SVAYVPQLAWIQNLSLRNNI-LFNRPYDAKLYQNVIENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKHIFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELM 828

HSP 4 Score: 67.0106 bits (162), Expect = 1.443e-10
Identity = 67/267 (25.09%), Postives = 117/267 (43.82%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVEVSP---PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALI------GELYKVSGRVMC-------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEA---CALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAV----DSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKN 2686
            V+++RIN++ +       +  ++P   P+   + I + +  +      VL  +   +     + +VG  G+GK+SL  AL       G   ++ G  +        R  +  +PQ     + +++ N+    P      +++ EA     L   +K L  G    I E G NLS GQ+Q I LARA+ +   V +LD+  +AV    DS + K I +Q           T + + H L  +   D++ V+  G V+E  T  +LL N
Sbjct: 1263 VAVERINEYTITPTEGNNSQSLAPKSWPENGEISIKNFSVRYRPGLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNL---DPFFAFSDDQIWEALRNAHLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQ-------FKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSN 1519
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Celegans
Match: mrp-1 (pep chromosome:WBcel235:X:576318:587483:-1 gene:WBGene00003407.1 transcript:F57C12.5b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mrp-1)

HSP 1 Score: 593.964 bits (1530), Expect = 0.000e+0
Identity = 343/888 (38.63%), Postives = 508/888 (57.21%), Query Frame = 2 
Query:   86 YDLI--GW--NTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLL--NFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIY-----KKGIHSSGVLFFYWLLQLLASITVI--YSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEK--QNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTL-SSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWG-KTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIG-PSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            Y+L+  GW  N+  P +T C Q+T  + IP LFL    +I+ PIL+ +   +Y++R  +    S +   I+F  LL  +  AT+      L+    LY              +   L+       +GI +SGV+  YWLL ++  +  +  Y   R  K ++    R     F ++   +   L+CFAD                           P +  I  N   CPE   SFL++LTF W +GL   G ++ L  +DL+ L E D  + I+ +       EN   +   +R+K++K  +     N+                            PS L  +F T  +  +  G +K+ +DLL F  P++L   I+FI++ N  +W G  +A+ +FL S+++S+I  QY+H  +  GM  R+ +   +Y K L LS+ +RK  T G IVNLMSVD Q++QD+ +F+ + W+AP+ I++++YFLW+ LG SVLAG  ++I LIP N  I  K++  Q +QMK KD RIK+M+EIL+G+K+LKLY+WE S E+ +  +R  E R+L+  +YLNA + ++W CAPFLVA+ TF  + L    ++VLT    FV+L+LFNIL FP+++   V    +Q   S  R+ +F   +E+  +        +  +K+  G+F+WG K E   L +I   +  G LVA+VG VGSGK+SL+ AL+GE+ K+SG V   GS+ Y+PQ AW +N SL++NILF++P     Y  VIE CAL +DL+ LPA D+TEIGEKGINLSGGQKQR+SLARAVYQ+  + LLDDPLSAVDSHVGKHIF+ VI   +G L +KTR+L+THGLTYL   D++ V+KD  +SE GT+ EL+ +NG+
Sbjct:   14 YELLETGWRNNSNIPQVTNCGQHTDFSTIPTLFL----VIFSPILFYE---LYKSRNSYLRSFSAISLRIIFCCLLVVDLTATVIYDFYLLFTKSPLYNAIHFYGDLVQYAGFCLALVLTIACRNRGIITSGVITLYWLLVVVCGVPELRYYITGRLYKEYEIHSCRAALYVFAYVCSALELFLSCFAD--------------------------TPSNGYIGKN--SCPEYTASFLNQLTFQWFSGLAYLGNKKSLEKEDLWDLNERDKAENIIPSF-----IENLIPEVEGYRRKIKKNPEAAIPKNH----------------------------PSILIPIFKTYKFTLLAGGCYKLMFDLLQFVAPELLRQLISFIEDKNQPMWIGVSIALLMFLSSLLQSMILHQYFHEMFRLGMNIRSVLTSAVYTKTLNLSNEARKGKTTGAIVNLMSVDIQRIQDMTTFIMLFWSAPLQILLSLYFLWKLLGVSVLAGFVILILLIPFNSFISVKMRNCQMEQMKFKDERIKMMSEILNGMKVLKLYSWEKSMEKMVLEVREKEIRVLKKLSYLNAATTLSWACAPFLVAVLTFGLYVLWDPENNVLTPQITFVALALFNILRFPLAVFAMVFSQAVQCSASNTRLKEFFAAEEMSPQTSIAYGGTDSAIKMDGGSFAWGSKEEDRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLSGSVQVNGSVAYVPQLAWIQNLSLRNNILFNRPYDAKLYQNVIENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKHIFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELMNSNGA 833

HSP 2 Score: 577.015 bits (1486), Expect = 3.397e-178
Identity = 302/588 (51.36%), Postives = 392/588 (66.67%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETG---STNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAM---YYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIG--SGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            E G VKF V++SY R+     +      Y       V +N++L+ W++     + +G  +       LGIY  LG GQA  +   +  +A G   AS+ LH  LL+NI+R+P +FFD TPLGRILNR GKDID +D  +P+ I  ++      +    V   ++P   L+  P+T +   YY   RFY+ TSRQLKR++S  RSPIYSHFQESI GASSIRAY V D FI++     DEN   +YP+IV+ RWL   LE +GNL++L S   AV  R + G  +G  GLS+SYAL IT  LN+ VRMTS+LE++ VAVERI EY    +E   N  +S A   WP++G +   N+SVRYRPGLDLVL  +   +   EK+GIVGRTGAGKSSL LALFR+IE   G I ID  +I  L L  LRS++TI+PQDP+LFSGT+RMNLDPF   SD ++W  L  ++L SF+    EGL + +SEGGENLSVGQ+QL+CLARALL+K+KVLVLDEA AAVD+ETD L+Q +IR QFK CTVLTIAHRLNT+MD DR++VL++G V E D+P+ LL+N   IF+SMA DA +
Sbjct:  951 ETGKVKFEVYMSYFRAIGIKIALVFFLVYVASSMLGVFSNLYLARWSDDAKEIALSGNGSSSETQIRLGIYAVLGMGQATSVCAASIIMALGMVCASRLLHATLLENIMRSPMAFFDVTPLGRILNRFGKDIDVIDYRLPSCIMTFVGAIVQAVTIFAVPIYATP---LSSFPITIVLIGYYFLLRFYVSTSRQLKRLESASRSPIYSHFQESIQGASSIRAYGVVDKFIRESQHRVDENLATYYPSIVANRWLAVRLEMVGNLIVLSSAGAAVYFRDSPGLSAGLVGLSVSYALNITQTLNWAVRMTSELETNIVAVERINEYTITPTEG--NNSQSLAPKSWPENGEISIKNFSVRYRPGLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNLDPFFAFSDDQIWEALRNAHLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQFKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSNPDGIFYSMAKDANV 1533

HSP 3 Score: 71.2478 bits (173), Expect = 5.949e-12
Identity = 58/214 (27.10%), Postives = 105/214 (49.07%), Query Frame = 2 
Query: 4070 DLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELW-SVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKC----TVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            D  L ++   +  G+ + IVGR G+GKSSL  AL   +    G++ ++               +  +PQ   + + ++R N+  FN+  D +L+ +V+E   L   +       +  + E G NLS GQKQ V LARA+ + +++++LD+  +AVD      I  ++      C    T + + H L  +   D+V+VL+   + E+ + Q L+
Sbjct:  629 DRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLSGSVQVNG-------------SVAYVPQLAWIQNLSLRNNI-LFNRPYDAKLYQNVIENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKHIFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELM 828

HSP 4 Score: 67.0106 bits (162), Expect = 1.407e-10
Identity = 67/267 (25.09%), Postives = 117/267 (43.82%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVEVSP---PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALI------GELYKVSGRVMC-------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEA---CALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAV----DSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKN 2686
            V+++RIN++ +       +  ++P   P+   + I + +  +      VL  +   +     + +VG  G+GK+SL  AL       G   ++ G  +        R  +  +PQ     + +++ N+    P      +++ EA     L   +K L  G    I E G NLS GQ+Q I LARA+ +   V +LD+  +AV    DS + K I +Q           T + + H L  +   D++ V+  G V+E  T  +LL N
Sbjct: 1263 VAVERINEYTITPTEGNNSQSLAPKSWPENGEISIKNFSVRYRPGLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNL---DPFFAFSDDQIWEALRNAHLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQ-------FKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSN 1519
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Fly
Match: MRP (gene:FBgn0032456 transcript:FBtr0090029)

HSP 1 Score: 706.057 bits (1821), Expect = 0.000e+0
Identity = 391/898 (43.54%), Postives = 558/898 (62.14%), Query Frame = 2 
Query:   80 LWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRN--RGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALY----LQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYR----RLKF------HDRDL----FRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPN-DYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFI 2710
             W     W T DPD T CF+ T L W P  F W    +     + KAS + RN    K N+ K+ +   +L    L+    + +   +   P  LY      PI+   + +LL     L  K G+ ++G  F +W L  + SI    +  R    R K        ++D     ++ V+    F    +  ILNCFAD        +   +Q+  +E                     PE   SFLS++T+ W   + +KGYR PL  KDL+ LR  D+C  ++      WN +N R K  K + ++E +  F++     ++   E              +KK   S +  ++ + G  ++   + K+  D LTFAQPQ+L L I+F++  + +  W G L A+ LF+++  ++ I  QY+H  ++ G+R RTA+I  IYRKAL++S++++KE+TVGEIVNLM+VD+Q+  ++ ++L+++W+AP+ I +A+YFLWQ+LGPSVLAG+A+MI LIP+NG+I S++K  Q +QMK KD R+KLMNE+LSGIK+LKLYAWE SFE+ + +IR+ E   LRS  YLNA ++  W CAPFLV+L TF  + L   ++VL A K FVSLSLFNIL FP++MLP +I   +Q  VS+ RINKFL  +ELD  +V        P+ I +G FSWG  +   L NIN+EV +GSLVA+VGTVGSGK+S++ A +GE+ K++G V   G + Y+PQQAW +NA+++DNILF +     +YN+VI+ACAL  D+ +L AGD TEIGEKGINLSGGQKQRISLARAVY D  +YLLDDPLSAVD+HVGKHIF++VIGP G+L+ K+R+LVTHG+T+LP+VD I+V+K G +SESGTF +L+KN G+FA+FI
Sbjct:   17 FWNATETWYTNDPDFTPCFEQTALVWTPCAFYW--AFVIFDFYYLKAS-LDRNIPWNKLNVSKALVNLGLLVITALDLIMALVKKGGDSELP--LYDLDVWGPIIKFATFLLLFIFIPLNRKYGVQTTGCQFIFWFLLTVLSIPRCRTEVRLDAERQKILNSQQPSEQDFSWEEYQFVSFFIFFTFTSIMLILNCFAD-----GMPRQTKYQRGENE--------------------IPELSASFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHHWN-QNVR-KNYKNKARVEPKAQFSNGNVTFENPHGEKN-----------GRKKGMASIMPPIYKSFGGVFLFGALMKLFTDTLTFAQPQVLSLIISFVEAQDAEPEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGPSVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRDKEIATLRSTAYLNAGTSFLWSCAPFLVSLVTFATYVLIDENNVLDATKTFVSLSLFNILRFPLTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSWG--DEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAFADFI 869

HSP 2 Score: 609.757 bits (1571), Expect = 0.000e+0
Identity = 306/583 (52.49%), Postives = 416/583 (71.36%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAY-GTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAH-SDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            ++ GGV+F+V+  YI+S     S   +    ++    +G+N++L+ W      N   +   +  YLG+YG+ G GQ +F  I +  + Y G  + ++ +   L  NIL AP ++FD  P  RIL+R+  DI  +DV +P  IR++      V+ +I VIS+S+P FL  +VP+  +YY AQRFY+ TSRQL R++S+ RSPIYSHF E++ GAS+IRAY V D FI++ D   D+NQ+  YP++++ RWL   LE +GNL+IL + + AV+   T   G  GLS+SYALQ+T  LN++VRM+SD+E++ V+VERIKEY E + EAPW +E+ +    +WP  GRVEF N+ VRYR GLDLVLR ++  +  GEK+GIVGRTGAGKSSL LALFR+IE A G I ID  DI  +GLH LRS++TIIPQDP+LFSG++R+NLDPF   +D E+W  LE+S+LKSF+   + GL + ++EGGENLSVGQ+QLVCLARALL+K+KVLVLDEATAAVDLETDDLIQ +IR +FK+CTVLTIAHRLNTI+D D+V+VL++G++ E  SP  LL N KS F+SMA DA L
Sbjct:  969 SQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVFQAFQIGSNLWLTQWAN--DQNVANDTGLRDMYLGVYGAFGFGQ-VFSYIGSVVIVYLGALIGTRKIFIQLFGNILHAPQAYFDIKPRARILDRLANDIYKLDVVLPELIRVFNSQVFRVLATIVVISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVIANRWLAIRLEMVGNLIILFASLFAVLGGQT-NPGLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKSAFYSMAKDANL 1547

HSP 3 Score: 80.4925 bits (197), Expect = 1.274e-14
Identity = 66/217 (30.41%), Postives = 100/217 (46.08%), Query Frame = 2 
Query: 2090 VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRV-------------MCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSK--TRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            VL  ++  +  G  V +VG  G+GK+SL  AL   +    GR+             M R  +  IPQ     + SL+ N+   +   + +  + +E   L   +K L AG   EI E G NLS GQ+Q + LARA+ +   V +LD+  +AVD        D +I  +     K  T + + H L  +   DK+ V+  G + E  + TELL N  S
Sbjct: 1325 VLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLET-----DDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKS 1536

HSP 4 Score: 77.0258 bits (188), Expect = 1.411e-13
Identity = 69/281 (24.56%), Postives = 129/281 (45.91%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNI--EESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWS-VLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            L  +  + ++L    V+V RI ++   E   P ++  + S+ H    ++G   +         G ++ LRN+NI V  G  + +VG  G+GKSS+  A    +E   G +             +   K+  +PQ   + + T+R N+  F Q  D + ++ V++   L++ I   S G    + E G NLS GQKQ + LARA+   + + +LD+  +AVD      I   +   +    + + + + H +  +   D + V++ G + E  +   L+ N+
Sbjct:  605 LTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSW---------GDEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVV-------------NTVGKLAYVPQQAWIQNATVRDNI-LFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNK 862
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Fly
Match: MRP (gene:FBgn0032456 transcript:FBtr0090021)

HSP 1 Score: 706.057 bits (1821), Expect = 0.000e+0
Identity = 391/898 (43.54%), Postives = 558/898 (62.14%), Query Frame = 2 
Query:   80 LWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRN--RGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALY----LQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYR----RLKF------HDRDL----FRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPN-DYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFI 2710
             W     W T DPD T CF+ T L W P  F W    +     + KAS + RN    K N+ K+ +   +L    L+    + +   +   P  LY      PI+   + +LL     L  K G+ ++G  F +W L  + SI    +  R    R K        ++D     ++ V+    F    +  ILNCFAD        +   +Q+  +E                     PE   SFLS++T+ W   + +KGYR PL  KDL+ LR  D+C  ++      WN +N R K  K + ++E +  F++     ++   E              +KK   S +  ++ + G  ++   + K+  D LTFAQPQ+L L I+F++  + +  W G L A+ LF+++  ++ I  QY+H  ++ G+R RTA+I  IYRKAL++S++++KE+TVGEIVNLM+VD+Q+  ++ ++L+++W+AP+ I +A+YFLWQ+LGPSVLAG+A+MI LIP+NG+I S++K  Q +QMK KD R+KLMNE+LSGIK+LKLYAWE SFE+ + +IR+ E   LRS  YLNA ++  W CAPFLV+L TF  + L   ++VL A K FVSLSLFNIL FP++MLP +I   +Q  VS+ RINKFL  +ELD  +V        P+ I +G FSWG  +   L NIN+EV +GSLVA+VGTVGSGK+S++ A +GE+ K++G V   G + Y+PQQAW +NA+++DNILF +     +YN+VI+ACAL  D+ +L AGD TEIGEKGINLSGGQKQRISLARAVY D  +YLLDDPLSAVD+HVGKHIF++VIGP G+L+ K+R+LVTHG+T+LP+VD I+V+K G +SESGTF +L+KN G+FA+FI
Sbjct:   17 FWNATETWYTNDPDFTPCFEQTALVWTPCAFYW--AFVIFDFYYLKAS-LDRNIPWNKLNVSKALVNLGLLVITALDLIMALVKKGGDSELP--LYDLDVWGPIIKFATFLLLFIFIPLNRKYGVQTTGCQFIFWFLLTVLSIPRCRTEVRLDAERQKILNSQQPSEQDFSWEEYQFVSFFIFFTFTSIMLILNCFAD-----GMPRQTKYQRGENE--------------------IPELSASFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHHWN-QNVR-KNYKNKARVEPKAQFSNGNVTFENPHGEKN-----------GRKKGMASIMPPIYKSFGGVFLFGALMKLFTDTLTFAQPQVLSLIISFVEAQDAEPEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGPSVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRDKEIATLRSTAYLNAGTSFLWSCAPFLVSLVTFATYVLIDENNVLDATKTFVSLSLFNILRFPLTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSWG--DEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAFADFI 869

HSP 2 Score: 613.994 bits (1582), Expect = 0.000e+0
Identity = 307/583 (52.66%), Postives = 415/583 (71.18%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAP-SSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAH-SDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            ++ GGV+F+V+  YI+S     S   +    ++    +G+N++L+ W      N   +   +  YLG+YG+ G GQ +        +  G F A+K++HN LL  I+R     FFD TP+GR+LN    D+D VD  +P T+  ++     V+ +I VIS+S+P FL  +VP+  +YY AQRFY+ TSRQL R++S+ RSPIYSHF E++ GAS+IRAY V D FI++ D   D+NQ+  YP++++ RWL   LE +GNL+IL + + AV+   T   G  GLS+SYALQ+T  LN++VRM+SD+E++ V+VERIKEY E + EAPW +E+ +    +WP  GRVEF N+ VRYR GLDLVLR ++  +  GEK+GIVGRTGAGKSSL LALFR+IE A G I ID  DI  +GLH LRS++TIIPQDP+LFSG++R+NLDPF   +D E+W  LE+S+LKSF+   + GL + ++EGGENLSVGQ+QLVCLARALL+K+KVLVLDEATAAVDLETDDLIQ +IR +FK+CTVLTIAHRLNTI+D D+V+VL++G++ E  SP  LL N KS F+SMA DA L
Sbjct:  969 SQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVFQAFQIGSNLWLTQWAN--DQNVANDTGLRDMYLGVYGAFGFGQGVLAYFAVVIVYLGGFQAAKTIHNELLAVIIRGSVCRFFDITPIGRLLNSFSGDMDVVDEELPATMDSFMTFIFMVLATIVVISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVIANRWLAIRLEMVGNLIILFASLFAVLGGQT-NPGLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKSAFYSMAKDANL 1548

HSP 3 Score: 80.4925 bits (197), Expect = 1.421e-14
Identity = 64/215 (29.77%), Postives = 97/215 (45.12%), Query Frame = 2 
Query: 2090 VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRV-------------MCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            VL  ++  +  G  V +VG  G+GK+SL  AL   +    GR+             M R  +  IPQ     + SL+ N+   +   + +  + +E   L   +K L AG   EI E G NLS GQ+Q + LARA+ +   V +LD+  +AVD      I   +          T + + H L  +   DK+ V+  G + E  + TELL N  S
Sbjct: 1326 VLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTI---RTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKS 1537

HSP 4 Score: 77.0258 bits (188), Expect = 1.423e-13
Identity = 69/281 (24.56%), Postives = 129/281 (45.91%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNI--EESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWS-VLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            L  +  + ++L    V+V RI ++   E   P ++  + S+ H    ++G   +         G ++ LRN+NI V  G  + +VG  G+GKSS+  A    +E   G +             +   K+  +PQ   + + T+R N+  F Q  D + ++ V++   L++ I   S G    + E G NLS GQKQ + LARA+   + + +LD+  +AVD      I   +   +    + + + + H +  +   D + V++ G + E  +   L+ N+
Sbjct:  605 LTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSW---------GDEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVV-------------NTVGKLAYVPQQAWIQNATVRDNI-LFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNK 862
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Fly
Match: MRP (gene:FBgn0032456 transcript:FBtr0090022)

HSP 1 Score: 705.671 bits (1820), Expect = 0.000e+0
Identity = 391/898 (43.54%), Postives = 558/898 (62.14%), Query Frame = 2 
Query:   80 LWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRN--RGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALY----LQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYR----RLKF------HDRDL----FRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPN-DYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFI 2710
             W     W T DPD T CF+ T L W P  F W    +     + KAS + RN    K N+ K+ +   +L    L+    + +   +   P  LY      PI+   + +LL     L  K G+ ++G  F +W L  + SI    +  R    R K        ++D     ++ V+    F    +  ILNCFAD        +   +Q+  +E                     PE   SFLS++T+ W   + +KGYR PL  KDL+ LR  D+C  ++      WN +N R K  K + ++E +  F++     ++   E              +KK   S +  ++ + G  ++   + K+  D LTFAQPQ+L L I+F++  + +  W G L A+ LF+++  ++ I  QY+H  ++ G+R RTA+I  IYRKAL++S++++KE+TVGEIVNLM+VD+Q+  ++ ++L+++W+AP+ I +A+YFLWQ+LGPSVLAG+A+MI LIP+NG+I S++K  Q +QMK KD R+KLMNE+LSGIK+LKLYAWE SFE+ + +IR+ E   LRS  YLNA ++  W CAPFLV+L TF  + L   ++VL A K FVSLSLFNIL FP++MLP +I   +Q  VS+ RINKFL  +ELD  +V        P+ I +G FSWG  +   L NIN+EV +GSLVA+VGTVGSGK+S++ A +GE+ K++G V   G + Y+PQQAW +NA+++DNILF +     +YN+VI+ACAL  D+ +L AGD TEIGEKGINLSGGQKQRISLARAVY D  +YLLDDPLSAVD+HVGKHIF++VIGP G+L+ K+R+LVTHG+T+LP+VD I+V+K G +SESGTF +L+KN G+FA+FI
Sbjct:   17 FWNATETWYTNDPDFTPCFEQTALVWTPCAFYW--AFVIFDFYYLKAS-LDRNIPWNKLNVSKALVNLGLLVITALDLIMALVKKGGDSELP--LYDLDVWGPIIKFATFLLLFIFIPLNRKYGVQTTGCQFIFWFLLTVLSIPRCRTEVRLDAERQKILNSQQPSEQDFSWEEYQFVSFFIFFTFTSIMLILNCFAD-----GMPRQTKYQRGENE--------------------IPELSASFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHHWN-QNVR-KNYKNKARVEPKAQFSNGNVTFENPHGEKN-----------GRKKGMASIMPPIYKSFGGVFLFGALMKLFTDTLTFAQPQVLSLIISFVEAQDAEPEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGPSVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRDKEIATLRSTAYLNAGTSFLWSCAPFLVSLVTFATYVLIDENNVLDATKTFVSLSLFNILRFPLTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSWG--DEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAFADFI 869

HSP 2 Score: 626.32 bits (1614), Expect = 0.000e+0
Identity = 313/582 (53.78%), Postives = 417/582 (71.65%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAH-SDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            ++ GGV+F+V+  YI+S     S   +    ++    +G+N++L+ W      N   +   +  YLG+YG+ G GQ       + A++ G    S+ LH  LL   LR P   FDTTPLGRI+NR  KDIDT+D  +P  IR+ +  A  V+ +I VIS+S+P FL  +VP+  +YY AQRFY+ TSRQL R++S+ RSPIYSHF E++ GAS+IRAY V D FI++ D   D+NQ+  YP++++ RWL   LE +GNL+IL + + AV+   T   G  GLS+SYALQ+T  LN++VRM+SD+E++ V+VERIKEY E + EAPW +E+ +    +WP  GRVEF N+ VRYR GLDLVLR ++  +  GEK+GIVGRTGAGKSSL LALFR+IE A G I ID  DI  +GLH LRS++TIIPQDP+LFSG++R+NLDPF   +D E+W  LE+S+LKSF+   + GL + ++EGGENLSVGQ+QLVCLARALL+K+KVLVLDEATAAVDLETDDLIQ +IR +FK+CTVLTIAHRLNTI+D D+V+VL++G++ E  SP  LL N KS F+SMA DA L
Sbjct:  969 SQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVFQAFQIGSNLWLTQWA--NDQNVANDTGLRDMYLGVYGAFGFGQVATNFFSSLAISLGCLKCSQLLHQTLLYYNLRWPMELFDTTPLGRIVNRFSKDIDTIDNVLPFNIRVVIGQAYMVLATIVVISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVIANRWLAIRLEMVGNLIILFASLFAVLGGQT-NPGLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKSAFYSMAKDANL 1547

HSP 3 Score: 80.4925 bits (197), Expect = 1.340e-14
Identity = 64/215 (29.77%), Postives = 97/215 (45.12%), Query Frame = 2 
Query: 2090 VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRV-------------MCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            VL  ++  +  G  V +VG  G+GK+SL  AL   +    GR+             M R  +  IPQ     + SL+ N+   +   + +  + +E   L   +K L AG   EI E G NLS GQ+Q + LARA+ +   V +LD+  +AVD      I   +          T + + H L  +   DK+ V+  G + E  + TELL N  S
Sbjct: 1325 VLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTI---RTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKS 1536

HSP 4 Score: 77.0258 bits (188), Expect = 1.459e-13
Identity = 69/281 (24.56%), Postives = 129/281 (45.91%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNI--EESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWS-VLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            L  +  + ++L    V+V RI ++   E   P ++  + S+ H    ++G   +         G ++ LRN+NI V  G  + +VG  G+GKSS+  A    +E   G +             +   K+  +PQ   + + T+R N+  F Q  D + ++ V++   L++ I   S G    + E G NLS GQKQ + LARA+   + + +LD+  +AVD      I   +   +    + + + + H +  +   D + V++ G + E  +   L+ N+
Sbjct:  605 LTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSW---------GDEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVV-------------NTVGKLAYVPQQAWIQNATVRDNI-LFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNK 862
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Fly
Match: MRP (gene:FBgn0032456 transcript:FBtr0090026)

HSP 1 Score: 705.671 bits (1820), Expect = 0.000e+0
Identity = 391/898 (43.54%), Postives = 558/898 (62.14%), Query Frame = 2 
Query:   80 LWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRN--RGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALY----LQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYR----RLKF------HDRDL----FRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPN-DYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFI 2710
             W     W T DPD T CF+ T L W P  F W    +     + KAS + RN    K N+ K+ +   +L    L+    + +   +   P  LY      PI+   + +LL     L  K G+ ++G  F +W L  + SI    +  R    R K        ++D     ++ V+    F    +  ILNCFAD        +   +Q+  +E                     PE   SFLS++T+ W   + +KGYR PL  KDL+ LR  D+C  ++      WN +N R K  K + ++E +  F++     ++   E              +KK   S +  ++ + G  ++   + K+  D LTFAQPQ+L L I+F++  + +  W G L A+ LF+++  ++ I  QY+H  ++ G+R RTA+I  IYRKAL++S++++KE+TVGEIVNLM+VD+Q+  ++ ++L+++W+AP+ I +A+YFLWQ+LGPSVLAG+A+MI LIP+NG+I S++K  Q +QMK KD R+KLMNE+LSGIK+LKLYAWE SFE+ + +IR+ E   LRS  YLNA ++  W CAPFLV+L TF  + L   ++VL A K FVSLSLFNIL FP++MLP +I   +Q  VS+ RINKFL  +ELD  +V        P+ I +G FSWG  +   L NIN+EV +GSLVA+VGTVGSGK+S++ A +GE+ K++G V   G + Y+PQQAW +NA+++DNILF +     +YN+VI+ACAL  D+ +L AGD TEIGEKGINLSGGQKQRISLARAVY D  +YLLDDPLSAVD+HVGKHIF++VIGP G+L+ K+R+LVTHG+T+LP+VD I+V+K G +SESGTF +L+KN G+FA+FI
Sbjct:   17 FWNATETWYTNDPDFTPCFEQTALVWTPCAFYW--AFVIFDFYYLKAS-LDRNIPWNKLNVSKALVNLGLLVITALDLIMALVKKGGDSELP--LYDLDVWGPIIKFATFLLLFIFIPLNRKYGVQTTGCQFIFWFLLTVLSIPRCRTEVRLDAERQKILNSQQPSEQDFSWEEYQFVSFFIFFTFTSIMLILNCFAD-----GMPRQTKYQRGENE--------------------IPELSASFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHHWN-QNVR-KNYKNKARVEPKAQFSNGNVTFENPHGEKN-----------GRKKGMASIMPPIYKSFGGVFLFGALMKLFTDTLTFAQPQVLSLIISFVEAQDAEPEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGPSVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRDKEIATLRSTAYLNAGTSFLWSCAPFLVSLVTFATYVLIDENNVLDATKTFVSLSLFNILRFPLTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSWG--DEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAFADFI 869

HSP 2 Score: 627.861 bits (1618), Expect = 0.000e+0
Identity = 308/582 (52.92%), Postives = 420/582 (72.16%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAH-SDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            ++ GGV+F+V+  YI+S     S   +    ++    +G+N++L+ W      N   +   +  YLG+YG+ G GQ +   +    L+ G   +++ +HN+LL   LR P   FD TPLGRI+NR  KD+DT+D ++P  +R+ ++    V+ +I VIS+S+P FL  +VP+  +YY AQRFY+ TSRQL R++S+ RSPIYSHF E++ GAS+IRAY V D FI++ D   D+NQ+  YP++++ RWL   LE +GNL+IL + + AV+   T   G  GLS+SYALQ+T  LN++VRM+SD+E++ V+VERIKEY E + EAPW +E+ +    +WP  GRVEF N+ VRYR GLDLVLR ++  +  GEK+GIVGRTGAGKSSL LALFR+IE A G I ID  DI  +GLH LRS++TIIPQDP+LFSG++R+NLDPF   +D E+W  LE+S+LKSF+   + GL + ++EGGENLSVGQ+QLVCLARALL+K+KVLVLDEATAAVDLETDDLIQ +IR +FK+CTVLTIAHRLNTI+D D+V+VL++G++ E  SP  LL N KS F+SMA DA L
Sbjct:  969 SQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVFQAFQIGSNLWLTQWAN--DQNVANDTGLRDMYLGVYGAFGFGQVVTGYLSTLILSLGCVYSARYMHNVLLHGTLRWPMEMFDITPLGRIVNRFSKDVDTIDNTLPLNLRVVILQLFAVLATIVVISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVIANRWLAIRLEMVGNLIILFASLFAVLGGQT-NPGLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKSAFYSMAKDANL 1547

HSP 3 Score: 80.4925 bits (197), Expect = 1.409e-14
Identity = 66/217 (30.41%), Postives = 100/217 (46.08%), Query Frame = 2 
Query: 2090 VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRV-------------MCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSK--TRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            VL  ++  +  G  V +VG  G+GK+SL  AL   +    GR+             M R  +  IPQ     + SL+ N+   +   + +  + +E   L   +K L AG   EI E G NLS GQ+Q + LARA+ +   V +LD+  +AVD        D +I  +     K  T + + H L  +   DK+ V+  G + E  + TELL N  S
Sbjct: 1325 VLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLET-----DDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKS 1536

HSP 4 Score: 77.0258 bits (188), Expect = 1.352e-13
Identity = 69/281 (24.56%), Postives = 129/281 (45.91%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNI--EESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWS-VLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            L  +  + ++L    V+V RI ++   E   P ++  + S+ H    ++G   +         G ++ LRN+NI V  G  + +VG  G+GKSS+  A    +E   G +             +   K+  +PQ   + + T+R N+  F Q  D + ++ V++   L++ I   S G    + E G NLS GQKQ + LARA+   + + +LD+  +AVD      I   +   +    + + + + H +  +   D + V++ G + E  +   L+ N+
Sbjct:  605 LTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSW---------GDEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVV-------------NTVGKLAYVPQQAWIQNATVRDNI-LFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNK 862
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Fly
Match: MRP (gene:FBgn0032456 transcript:FBtr0090023)

HSP 1 Score: 705.671 bits (1820), Expect = 0.000e+0
Identity = 391/898 (43.54%), Postives = 558/898 (62.14%), Query Frame = 2 
Query:   80 LWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRN--RGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALY----LQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYR----RLKF------HDRDL----FRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPN-DYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFI 2710
             W     W T DPD T CF+ T L W P  F W    +     + KAS + RN    K N+ K+ +   +L    L+    + +   +   P  LY      PI+   + +LL     L  K G+ ++G  F +W L  + SI    +  R    R K        ++D     ++ V+    F    +  ILNCFAD        +   +Q+  +E                     PE   SFLS++T+ W   + +KGYR PL  KDL+ LR  D+C  ++      WN +N R K  K + ++E +  F++     ++   E              +KK   S +  ++ + G  ++   + K+  D LTFAQPQ+L L I+F++  + +  W G L A+ LF+++  ++ I  QY+H  ++ G+R RTA+I  IYRKAL++S++++KE+TVGEIVNLM+VD+Q+  ++ ++L+++W+AP+ I +A+YFLWQ+LGPSVLAG+A+MI LIP+NG+I S++K  Q +QMK KD R+KLMNE+LSGIK+LKLYAWE SFE+ + +IR+ E   LRS  YLNA ++  W CAPFLV+L TF  + L   ++VL A K FVSLSLFNIL FP++MLP +I   +Q  VS+ RINKFL  +ELD  +V        P+ I +G FSWG  +   L NIN+EV +GSLVA+VGTVGSGK+S++ A +GE+ K++G V   G + Y+PQQAW +NA+++DNILF +     +YN+VI+ACAL  D+ +L AGD TEIGEKGINLSGGQKQRISLARAVY D  +YLLDDPLSAVD+HVGKHIF++VIGP G+L+ K+R+LVTHG+T+LP+VD I+V+K G +SESGTF +L+KN G+FA+FI
Sbjct:   17 FWNATETWYTNDPDFTPCFEQTALVWTPCAFYW--AFVIFDFYYLKAS-LDRNIPWNKLNVSKALVNLGLLVITALDLIMALVKKGGDSELP--LYDLDVWGPIIKFATFLLLFIFIPLNRKYGVQTTGCQFIFWFLLTVLSIPRCRTEVRLDAERQKILNSQQPSEQDFSWEEYQFVSFFIFFTFTSIMLILNCFAD-----GMPRQTKYQRGENE--------------------IPELSASFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHHWN-QNVR-KNYKNKARVEPKAQFSNGNVTFENPHGEKN-----------GRKKGMASIMPPIYKSFGGVFLFGALMKLFTDTLTFAQPQVLSLIISFVEAQDAEPEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGPSVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRDKEIATLRSTAYLNAGTSFLWSCAPFLVSLVTFATYVLIDENNVLDATKTFVSLSLFNILRFPLTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSWG--DEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAFADFI 869

HSP 2 Score: 626.706 bits (1615), Expect = 0.000e+0
Identity = 311/582 (53.44%), Postives = 415/582 (71.31%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAH-SDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            ++ GGV+F+V+  YI+S     S   +    ++    +G+N++L+ W      N   +   +  YLG+YG+ G GQ       +  LA G    SK LH  LL  + R P   FDTTPLGR++NR  KD+DT+D  +P   R+ +  A  V+ +I VIS+S+P FL  +VP+  +YY AQRFY+ TSRQL R++S+ RSPIYSHF E++ GAS+IRAY V D FI++ D   D+NQ+  YP++++ RWL   LE +GNL+IL + + AV+   T   G  GLS+SYALQ+T  LN++VRM+SD+E++ V+VERIKEY E + EAPW +E+ +    +WP  GRVEF N+ VRYR GLDLVLR ++  +  GEK+GIVGRTGAGKSSL LALFR+IE A G I ID  DI  +GLH LRS++TIIPQDP+LFSG++R+NLDPF   +D E+W  LE+S+LKSF+   + GL + ++EGGENLSVGQ+QLVCLARALL+K+KVLVLDEATAAVDLETDDLIQ +IR +FK+CTVLTIAHRLNTI+D D+V+VL++G++ E  SP  LL N KS F+SMA DA L
Sbjct:  969 SQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVFQAFQIGSNLWLTQWA--NDQNVANDTGLRDMYLGVYGAFGFGQVTSYFFCSLTLALGCIFCSKVLHETLLSYVFRWPMELFDTTPLGRVVNRFSKDVDTIDNVLPMLWRMVISQAFAVLATIVVISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVIANRWLAIRLEMVGNLIILFASLFAVLGGQT-NPGLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKSAFYSMAKDANL 1547

HSP 3 Score: 80.4925 bits (197), Expect = 1.170e-14
Identity = 64/215 (29.77%), Postives = 97/215 (45.12%), Query Frame = 2 
Query: 2090 VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRV-------------MCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            VL  ++  +  G  V +VG  G+GK+SL  AL   +    GR+             M R  +  IPQ     + SL+ N+   +   + +  + +E   L   +K L AG   EI E G NLS GQ+Q + LARA+ +   V +LD+  +AVD      I   +          T + + H L  +   DK+ V+  G + E  + TELL N  S
Sbjct: 1325 VLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTI---RTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKS 1536

HSP 4 Score: 77.411 bits (189), Expect = 1.233e-13
Identity = 69/281 (24.56%), Postives = 129/281 (45.91%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNI--EESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWS-VLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            L  +  + ++L    V+V RI ++   E   P ++  + S+ H    ++G   +         G ++ LRN+NI V  G  + +VG  G+GKSS+  A    +E   G +             +   K+  +PQ   + + T+R N+  F Q  D + ++ V++   L++ I   S G    + E G NLS GQKQ + LARA+   + + +LD+  +AVD      I   +   +    + + + + H +  +   D + V++ G + E  +   L+ N+
Sbjct:  605 LTMLPMLITNLVQTQVSVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSW---------GDEITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAGVV-------------NTVGKLAYVPQQAWIQNATVRDNI-LFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNK 862
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Zebrafish
Match: abcc1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 1 [Source:ZFIN;Acc:ZDB-GENE-050517-15])

HSP 1 Score: 773.467 bits (1996), Expect = 0.000e+0
Identity = 405/901 (44.95%), Postives = 574/901 (63.71%), Query Frame = 2 
Query:   47 SLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNK----ASFIYRNRGKFNIFKSTLIAFILFF-HLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR---DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKP--VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            S CS   +D  LW     W T  PD+T CFQ T+L WIP L+LW+   +YI  L +         + NR K      T+I F L+     +   +  E        P   + P +  ++ +L  +L +    KG+ SSGV+  +WL+ ++ +     S+      +D     +FR  T    + L+ +S IL C +D                     PL S +  D        PCPE+  SFLSK+TF W+TGL++KGY++PL  KDL++L   D  + +V  +  +W++E  +VK+    K L      T   K      EE+EI           QK   PS   AL  T G  ++++ ++K+ +D+L F  P+IL L I F+++ +   WHG+     LF+ + ++++I Q+Y+H C+VTGMR RTA++G +YRKAL +++ +R+ +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+YFLWQ LG SVLAGVA+M+ ++P+N +I  K K  Q  QMK KDNRIKLMNE+L+GIK+LKLYAWE +F+  +  IR  E R+L+   YL A+S  TW CAPFLVAL TF  + L   +++L A KAFVSL+LFNIL FP++MLP VI   +QA VS++R+  FL  +ELD +NVE       P  ++I DG FSW K + P L  IN+ +PEG+LVAVVG VGSGK+SL+SAL+GE++K  G V  +GS+ Y+PQQAW +NA+L+DNILF +   +  Y +V+EACAL  DL++LP GD TEIGEKG+NLSGGQKQR+S+ARAVY +CSVYLLDDPLSAVD+HVGKHIF++VIGP GLL  +TR+LVTHGL++LP+ D I VM DG ++E G++TELL   G+FAEF+RTY
Sbjct:    5 SFCSLDGSD-PLWDWNRTWQTYYPDLTPCFQNTVLVWIPCLYLWLFAPLYILYLKSHDRGYICMTHLNRAK------TVIGFTLWLICWADVFYSFWERSHGATVAPVYLVSPTMLGVTMLLATFLIQYERMKGVQSSGVMLNFWLITIVCATITFRSKIMH-ALNDPASVGVFRYTTFYIYYTLLLISLILACLSD-------------------QPPLFSEVVKDSN------PCPESGASFLSKITFWWITGLMVKGYKRPLEEKDLWSLNNEDKSERVVPQLVRRWDQECVKVKR-PVDKTLYSPKRSTRGEKKDGQPVEESEI-----LLAKALQKTGEPSLFFALCRTFGPYFLVSSLYKIIHDVLMFVGPEILRLLILFVNDSSAPTWHGYFYTALLFVCTCLQTLILQKYFHVCFVTGMRLRTAIVGAVYRKALVITNAARRTSTVGEIVNLMSVDAQRFMDLITYINMIWSAPLQVILALYFLWQNLGASVLAGVAVMVLMVPLNAVIAMKTKTYQVAQMKSKDNRIKLMNEVLNGIKVLKLYAWELAFKGKVSAIRESELRVLKKMAYLGAISTFTWVCAPFLVALSTFAVYVLVDENNILDAQKAFVSLALFNILRFPLNMLPMVISSMVQASVSMQRLRVFLSHEELDDDNVERPAISGTPDSIRIADGAFSWSKDDPPTLKRINVSIPEGALVAVVGHVGSGKSSLLSALLGEMHKQEGSVSIKGSVAYVPQQAWIQNATLKDNILFGRETKDSWYQKVVEACALLPDLEILPGGDTTEIGEKGVNLSGGQKQRVSVARAVYCNCSVYLLDDPLSAVDAHVGKHIFEKVIGPQGLLQGRTRVLVTHGLSFLPQADLILVMVDGEITEMGSYTELLGRQGAFAEFLRTY 866

HSP 2 Score: 598.201 bits (1541), Expect = 0.000e+0
Identity = 294/581 (50.60%), Postives = 418/581 (71.94%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A  G VK SVF  Y+++     S   +F +  +   S+G+N +LS WT+    N TQ P  +   LG+YG+LG  Q + +   + +++ G  LAS+ LH  +L N+LR+P SFF+ TP G ++NR  K+ DT+D  IP+ I++++ +   V+GS  VI I++P   + + PL  +Y+  QRFY+ +SRQ+KR++S+ RSP+Y+HF E+++G S IRA+     FIK+ D   D NQ A++P+IV+ RWL   LE +GN ++  + + AV+ R+ +  G  GLSISYALQ+T  LN++VRM+S+LE++ VAVER+KEY + E EA W +E S     WP +G +E   + +RYR  L+L + ++++ +  GEK+GIVGRTGAGKSSL L LFR+IE AEG I ID  +I  LGLH+LRS+ITIIPQDP+LFSG++RMNLDPF+ ++D E+W  LE+++LK+F++   + L +  SEGGENLS+GQ+QLVCLARALL+K+K+LVLDEATAAVDLETD+LIQS+IR QF+ CTVLTIAHRLNTIMDY RV+VL++G++ E DSP NL+A +K IF+ MA D+GL
Sbjct:  940 ANTGRVKLSVFWEYMKAIGLPLSIFSIFLFFCHHLSSLGSNYWLSLWTDDPVVNNTQ-PKRE-MRLGVYGALGISQGIAVFCYSVSVSVGGILASRYLHQTMLYNVLRSPMSFFERTPSGNLVNRFAKETDTIDSVIPSIIKMFMGSMFNVLGSCAVILIATPLVAIIIPPLGLLYFFVQRFYVASSRQMKRLESVSRSPVYTHFNETLLGTSVIRAFGEQQRFIKESDGRVDHNQKAYFPSIVANRWLAVRLEFVGNCIVTFAALFAVMARNNLSPGIMGLSISYALQVTASLNWLVRMSSELETNIVAVERVKEYGDTEKEAEWKLENSNLPPGWPTAGHIEIHKFGLRYREDLELAICDISVNIAGGEKVGIVGRTGAGKSSLTLGLFRIIEAAEGEIRIDGVNIADLGLHELRSRITIIPQDPVLFSGSLRMNLDPFDGYTDEEVWRSLELAHLKTFVSGLPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGQMAEFDSPSNLIA-KKGIFYKMAKDSGL 1517

HSP 3 Score: 77.0258 bits (188), Expect = 1.771e-13
Identity = 70/280 (25.00%), Postives = 125/280 (44.64%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKS 4711
            LN +  + S +   +V+++R++ +   E     N+E   A S  PDS R+    +S  +       L+ +N+ +  G  + +VG  G+GKSSL  AL   +   EG++ I             +  +  +PQ   + + T++ N+    +  D     V+E   L   +     G    + E G NLS GQKQ V +ARA+     V +LD+  +AVD      I   +   +   +  T + + H L+ +   D ++V+  G + E+ S   LL  + +
Sbjct:  595 LNMLPMVISSMVQASVSMQRLRVFLSHEELDDDNVERP-AISGTPDSIRIADGAFS--WSKDDPPTLKRINVSIPEGALVAVVGHVGSGKSSLLSALLGEMHKQEGSVSI-------------KGSVAYVPQQAWIQNATLKDNILFGRETKDSWYQKVVEACALLPDLEILPGGDTTEIGEKGVNLSGGQKQRVSVARAVYCNCSVYLLDDPLSAVDAHVGKHIFEKVIGPQGLLQGRTRVLVTHGLSFLPQADLILVMVDGEITEMGSYTELLGRQGA 858

HSP 4 Score: 64.3142 bits (155), Expect = 1.618e-9
Identity = 91/430 (21.16%), Postives = 174/430 (40.47%), Query Frame = 2 
Query: 1520 VLAGVALMICLIPINGIIGSKVKKL---QAKQMKMKDNRIK-----LMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRS-ATYLNAVSAVTWFCAPF-LVALC--TFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGD-----ELDTENVEVSP--PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIR 2713
            +L    L+  +IP  G++   V++     ++QMK  ++  +       NE L G  +++ +  +  F      I+  + R+  +   Y  ++ A  W       V  C  TF A     + + L+     +S+S    ++  ++ L  +        V+++R+ ++  GD     E   EN  + P  P    ++I      + +     + +I++ +  G  V +VG  G+GK+SL   L   +    G +               R  I  IPQ     + SL+ N+       + +  R +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G ++E  + + L+   G F +  +
Sbjct: 1095 ILIATPLVAIIIPPLGLLYFFVQRFYVASSRQMKRLESVSRSPVYTHFNETLLGTSVIRAFGEQQRF------IKESDGRVDHNQKAYFPSIVANRWLAVRLEFVGNCIVTFAALFAVMARNNLSPGIMGLSISYALQVTASLNWLVRMSSELETNIVAVERVKEY--GDTEKEAEWKLENSNLPPGWPTAGHIEIHKFGLRYREDLELAICDISVNIAGGEKVGIVGRTGAGKSSLTLGLFRIIEAAEGEIRIDGVNIADLGLHELRSRITIIPQDPVLFSGSLRMNLDPFDGYTDEEVWRSLELAHLKTFVSGLPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTI---RTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGQMAEFDSPSNLIAKKGIFYKMAK 1513
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Zebrafish
Match: abcc1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 1 [Source:ZFIN;Acc:ZDB-GENE-050517-15])

HSP 1 Score: 770 bits (1987), Expect = 0.000e+0
Identity = 405/909 (44.55%), Postives = 575/909 (63.26%), Query Frame = 2 
Query:   47 SLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNK----ASFIYRNRGKFNIFKSTLIAFILFF-HLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYK--------KGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR---DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKP--VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            S CS   +D  LW     W T  PD+T CFQ T+L WIP L+LW+   +YI  L +         + NR K      T+I F L+     +   +  E        P   + P +     ++ +Y+ +L+          KG+ SSGV+  +WL+ ++ +     S+      +D     +FR  T    + L+ +S IL C +D                     PL S +  D        PCPE+  SFLSK+TF W+TGL++KGY++PL  KDL++L   D  + +V  +  +W++E  +VK+    K L      T   K      EE+EI           QK   PS   AL  T G  ++++ ++K+ +D+L F  P+IL L I F+++ +   WHG+     LF+ + ++++I Q+Y+H C+VTGMR RTA++G +YRKAL +++ +R+ +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+YFLWQ LG SVLAGVA+M+ ++P+N +I  K K  Q  QMK KDNRIKLMNE+L+GIK+LKLYAWE +F+  +  IR  E R+L+   YL A+S  TW CAPFLVAL TF  + L   +++L A KAFVSL+LFNIL FP++MLP VI   +QA VS++R+  FL  +ELD +NVE       P  ++I DG FSW K + P L  IN+ +PEG+LVAVVG VGSGK+SL+SAL+GE++K  G V  +GS+ Y+PQQAW +NA+L+DNILF +   +  Y +V+EACAL  DL++LP GD TEIGEKG+NLSGGQKQR+S+ARAVY +CSVYLLDDPLSAVD+HVGKHIF++VIGP GLL  +TR+LVTHGL++LP+ D I VM DG ++E G++TELL   G+FAEF+RTY
Sbjct:    5 SFCSLDGSD-PLWDWNRTWQTYYPDLTPCFQNTVLVWIPCLYLWLFAPLYILYLKSHDRGYICMTHLNRAK------TVIGFTLWLICWADVFYSFWERSHGATVAPVYLVSPTMLGHGLLMFMYVFQLLATFLIQYERMKGVQSSGVMLNFWLITIVCATITFRSKIMH-ALNDPASVGVFRYTTFYIYYTLLLISLILACLSD-------------------QPPLFSEVVKDSN------PCPESGASFLSKITFWWITGLMVKGYKRPLEEKDLWSLNNEDKSERVVPQLVRRWDQECVKVKR-PVDKTLYSPKRSTRGEKKDGQPVEESEI-----LLAKALQKTGEPSLFFALCRTFGPYFLVSSLYKIIHDVLMFVGPEILRLLILFVNDSSAPTWHGYFYTALLFVCTCLQTLILQKYFHVCFVTGMRLRTAIVGAVYRKALVITNAARRTSTVGEIVNLMSVDAQRFMDLITYINMIWSAPLQVILALYFLWQNLGASVLAGVAVMVLMVPLNAVIAMKTKTYQVAQMKSKDNRIKLMNEVLNGIKVLKLYAWELAFKGKVSAIRESELRVLKKMAYLGAISTFTWVCAPFLVALSTFAVYVLVDENNILDAQKAFVSLALFNILRFPLNMLPMVISSMVQASVSMQRLRVFLSHEELDDDNVERPAISGTPDSIRIADGAFSWSKDDPPTLKRINVSIPEGALVAVVGHVGSGKSSLLSALLGEMHKQEGSVSIKGSVAYVPQQAWIQNATLKDNILFGRETKDSWYQKVVEACALLPDLEILPGGDTTEIGEKGVNLSGGQKQRVSVARAVYCNCSVYLLDDPLSAVDAHVGKHIFEKVIGPQGLLQGRTRVLVTHGLSFLPQADLILVMVDGEITEMGSYTELLGRQGAFAEFLRTY 874

HSP 2 Score: 598.971 bits (1543), Expect = 0.000e+0
Identity = 294/581 (50.60%), Postives = 418/581 (71.94%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A  G VK SVF  Y+++     S   +F +  +   S+G+N +LS WT+    N TQ P  +   LG+YG+LG  Q + +   + +++ G  LAS+ LH  +L N+LR+P SFF+ TP G ++NR  K+ DT+D  IP+ I++++ +   V+GS  VI I++P   + + PL  +Y+  QRFY+ +SRQ+KR++S+ RSP+Y+HF E+++G S IRA+     FIK+ D   D NQ A++P+IV+ RWL   LE +GN ++  + + AV+ R+ +  G  GLSISYALQ+T  LN++VRM+S+LE++ VAVER+KEY + E EA W +E S     WP +G +E   + +RYR  L+L + ++++ +  GEK+GIVGRTGAGKSSL L LFR+IE AEG I ID  +I  LGLH+LRS+ITIIPQDP+LFSG++RMNLDPF+ ++D E+W  LE+++LK+F++   + L +  SEGGENLS+GQ+QLVCLARALL+K+K+LVLDEATAAVDLETD+LIQS+IR QF+ CTVLTIAHRLNTIMDY RV+VL++G++ E DSP NL+A +K IF+ MA D+GL
Sbjct:  920 ANTGRVKLSVFWEYMKAIGLPLSIFSIFLFFCHHLSSLGSNYWLSLWTDDPVVNNTQ-PKRE-MRLGVYGALGISQGIAVFCYSVSVSVGGILASRYLHQTMLYNVLRSPMSFFERTPSGNLVNRFAKETDTIDSVIPSIIKMFMGSMFNVLGSCAVILIATPLVAIIIPPLGLLYFFVQRFYVASSRQMKRLESVSRSPVYTHFNETLLGTSVIRAFGEQQRFIKESDGRVDHNQKAYFPSIVANRWLAVRLEFVGNCIVTFAALFAVMARNNLSPGIMGLSISYALQVTASLNWLVRMSSELETNIVAVERVKEYGDTEKEAEWKLENSNLPPGWPTAGHIEIHKFGLRYREDLELAICDISVNIAGGEKVGIVGRTGAGKSSLTLGLFRIIEAAEGEIRIDGVNIADLGLHELRSRITIIPQDPVLFSGSLRMNLDPFDGYTDEEVWRSLELAHLKTFVSGLPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGQMAEFDSPSNLIA-KKGIFYKMAKDSGL 1497

HSP 3 Score: 77.7962 bits (190), Expect = 1.207e-13
Identity = 70/280 (25.00%), Postives = 125/280 (44.64%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKS 4711
            LN +  + S +   +V+++R++ +   E     N+E   A S  PDS R+    +S  +       L+ +N+ +  G  + +VG  G+GKSSL  AL   +   EG++ I             +  +  +PQ   + + T++ N+    +  D     V+E   L   +     G    + E G NLS GQKQ V +ARA+     V +LD+  +AVD      I   +   +   +  T + + H L+ +   D ++V+  G + E+ S   LL  + +
Sbjct:  603 LNMLPMVISSMVQASVSMQRLRVFLSHEELDDDNVERP-AISGTPDSIRIADGAFS--WSKDDPPTLKRINVSIPEGALVAVVGHVGSGKSSLLSALLGEMHKQEGSVSI-------------KGSVAYVPQQAWIQNATLKDNILFGRETKDSWYQKVVEACALLPDLEILPGGDTTEIGEKGVNLSGGQKQRVSVARAVYCNCSVYLLDDPLSAVDAHVGKHIFEKVIGPQGLLQGRTRVLVTHGLSFLPQADLILVMVDGEITEMGSYTELLGRQGA 866

HSP 4 Score: 64.6994 bits (156), Expect = 1.032e-9
Identity = 63/273 (23.08%), Postives = 113/273 (41.39%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGD-----ELDTENVEVSP--PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIR 2713
            V+++R+ ++  GD     E   EN  + P  P    ++I      + +     + +I++ +  G  V +VG  G+GK+SL   L   +    G +               R  I  IPQ     + SL+ N+       + +  R +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G ++E  + + L+   G F +  +
Sbjct: 1226 VAVERVKEY--GDTEKEAEWKLENSNLPPGWPTAGHIEIHKFGLRYREDLELAICDISVNIAGGEKVGIVGRTGAGKSSLTLGLFRIIEAAEGEIRIDGVNIADLGLHELRSRITIIPQDPVLFSGSLRMNLDPFDGYTDEEVWRSLELAHLKTFVSGLPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTI---RTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGQMAEFDSPSNLIAKKGIFYKMAK 1493
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Zebrafish
Match: abcc1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 1 [Source:ZFIN;Acc:ZDB-GENE-050517-15])

HSP 1 Score: 764.992 bits (1974), Expect = 0.000e+0
Identity = 405/931 (43.50%), Postives = 579/931 (62.19%), Query Frame = 2 
Query:   47 SLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNK----ASFIYRNRGKFNIFKSTLIAFILFF-HLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR---DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFR-------KKLEKQNGFTSN-------------------YKPLKSEEEETE----IDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKP--VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            S CS   +D  LW     W T  PD+T CFQ T+L WIP L+LW+   +YI  L +         + NR K      T+I F L+     +   +  E        P   + P +  ++ +L  +L +    KG+ SSGV+  +WL+ ++ +     S+      +D     +FR  T    + L+ +S IL C +D                     PL S +  D        PCPE+  SFLSK+TF W+TGL++KGY++PL  KDL++L   D  + +V  +  +W++E  +VK++  R        K  K      N                   Y P +S   E +    ++  +       QK   PS   AL  T G  ++++ ++K+ +D+L F  P+IL L I F+++ +   WHG+     LF+ + ++++I Q+Y+H C+VTGMR RTA++G +YRKAL +++ +R+ +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+YFLWQ LG SVLAGVA+M+ ++P+N +I  K K  Q  QMK KDNRIKLMNE+L+GIK+LKLYAWE +F+  +  IR  E R+L+   YL A+S  TW CAPFLVAL TF  + L   +++L A KAFVSL+LFNIL FP++MLP VI   +QA VS++R+  FL  +ELD +NVE       P  ++I DG FSW K + P L  IN+ +PEG+LVAVVG VGSGK+SL+SAL+GE++K  G V  +GS+ Y+PQQAW +NA+L+DNILF +   +  Y +V+EACAL  DL++LP GD TEIGEKG+NLSGGQKQR+S+ARAVY +CSVYLLDDPLSAVD+HVGKHIF++VIGP GLL  +TR+LVTHGL++LP+ D I VM DG ++E G++TELL   G+FAEF+RTY
Sbjct:    5 SFCSLDGSD-PLWDWNRTWQTYYPDLTPCFQNTVLVWIPCLYLWLFAPLYILYLKSHDRGYICMTHLNRAK------TVIGFTLWLICWADVFYSFWERSHGATVAPVYLVSPTMLGVTMLLATFLIQYERMKGVQSSGVMLNFWLITIVCATITFRSKIMH-ALNDPASVGVFRYTTFYIYYTLLLISLILACLSD-------------------QPPLFSEVVKDSN------PCPESGASFLSKITFWWITGLMVKGYKRPLEEKDLWSLNNEDKSERVVPQLVRRWDQECVKVKRSDRRVRFLIVFSKTIKTVDLLQNWLILWLVYVFCARPVDKTLYSPKRSTRGEKKDGQPVEESEILLAKALQKTGEPSLFFALCRTFGPYFLVSSLYKIIHDVLMFVGPEILRLLILFVNDSSAPTWHGYFYTALLFVCTCLQTLILQKYFHVCFVTGMRLRTAIVGAVYRKALVITNAARRTSTVGEIVNLMSVDAQRFMDLITYINMIWSAPLQVILALYFLWQNLGASVLAGVAVMVLMVPLNAVIAMKTKTYQVAQMKSKDNRIKLMNEVLNGIKVLKLYAWELAFKGKVSAIRESELRVLKKMAYLGAISTFTWVCAPFLVALSTFAVYVLVDENNILDAQKAFVSLALFNILRFPLNMLPMVISSMVQASVSMQRLRVFLSHEELDDDNVERPAISGTPDSIRIADGAFSWSKDDPPTLKRINVSIPEGALVAVVGHVGSGKSSLLSALLGEMHKQEGSVSIKGSVAYVPQQAWIQNATLKDNILFGRETKDSWYQKVVEACALLPDLEILPGGDTTEIGEKGVNLSGGQKQRVSVARAVYCNCSVYLLDDPLSAVDAHVGKHIFEKVIGPQGLLQGRTRVLVTHGLSFLPQADLILVMVDGEITEMGSYTELLGRQGAFAEFLRTY 902

HSP 2 Score: 266.929 bits (681), Expect = 4.707e-72
Identity = 136/323 (42.11%), Postives = 211/323 (65.33%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESE 3970
            A  G VK SVF  Y+++     S   +F +  +   S+G+N +LS WT+    N TQ P  +   LG+YG+LG  Q + +   + +++ G  LAS+ LH  +L N+LR+P SFF+ TP G ++NR  K+ DT+D  IP+ I++++ +   V+GS  VI I++P   + + PL  +Y+  QRFY+ +SRQ+KR++S+ RSP+Y+HF E+++G S IRA+     FIK+ D   D NQ A++P+IV+ RWL   LE +GN ++  + + AV+ R+ +  G  GLSISYALQ+T  LN++VRM+S+LE++ VAVER+KEY + E E
Sbjct:  976 ANTGRVKLSVFWEYMKAIGLPLSIFSIFLFFCHHLSSLGSNYWLSLWTDDPVVNNTQ-PKRE-MRLGVYGALGISQGIAVFCYSVSVSVGGILASRYLHQTMLYNVLRSPMSFFERTPSGNLVNRFAKETDTIDSVIPSIIKMFMGSMFNVLGSCAVILIATPLVAIIIPPLGLLYFFVQRFYVASSRQMKRLESVSRSPVYTHFNETLLGTSVIRAFGEQQRFIKESDGRVDHNQKAYFPSIVANRWLAVRLEFVGNCIVTFAALFAVMARNNLSPGIMGLSISYALQVTASLNWLVRMSSELETNIVAVERVKEYGDTEKE 1296

HSP 3 Score: 77.7962 bits (190), Expect = 1.071e-13
Identity = 70/280 (25.00%), Postives = 125/280 (44.64%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKS 4711
            LN +  + S +   +V+++R++ +   E     N+E   A S  PDS R+    +S  +       L+ +N+ +  G  + +VG  G+GKSSL  AL   +   EG++ I             +  +  +PQ   + + T++ N+    +  D     V+E   L   +     G    + E G NLS GQKQ V +ARA+     V +LD+  +AVD      I   +   +   +  T + + H L+ +   D ++V+  G + E+ S   LL  + +
Sbjct:  631 LNMLPMVISSMVQASVSMQRLRVFLSHEELDDDNVERP-AISGTPDSIRIADGAFS--WSKDDPPTLKRINVSIPEGALVAVVGHVGSGKSSLLSALLGEMHKQEGSVSI-------------KGSVAYVPQQAWIQNATLKDNILFGRETKDSWYQKVVEACALLPDLEILPGGDTTEIGEKGVNLSGGQKQRVSVARAVYCNCSVYLLDDPLSAVDAHVGKHIFEKVIGPQGLLQGRTRVLVTHGLSFLPQADLILVMVDGEITEMGSYTELLGRQGA 894
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Zebrafish
Match: abcc3 (ATP-binding cassette, sub-family C (CFTR/MRP), member 3 [Source:ZFIN;Acc:ZDB-GENE-050517-16])

HSP 1 Score: 759.214 bits (1959), Expect = 0.000e+0
Identity = 410/905 (45.30%), Postives = 563/905 (62.21%), Query Frame = 2 
Query:   50 LCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILW-NKASFIYR---NRGKFNIFKSTLIAFILF----------FHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVE-VSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            LC      W L   L G   Q PD+  CFQ ++L+W P ++LW +  +YI  L  N   +I     NR K      T++  IL+          FH +N  + IS         P  ++ P++  ++ +L  +L +    KG+ SSGVLF +W L ++ +I    S+        +D  R  T    F    +  IL+CF                   +E  PL S    D  +      CPE    FLS++TF W T + IKGY+ PL  KDL++L +ND+ + +V  +  QW  E  +   +   + +++Q  FT      +S       +  +   + ++QK + PSFL AL    G  +++   FK+  DL+TF  PQ+L + I F    +   W G+ LA  +F  S+++++I  Q++  C+VTGMR RT +IG IYRKAL +++ +++ +TVGE+VNLMSVD+Q+  D+ +FL++LW+AP+ I +A++FLWQ LGPSVLAGVA+M+ LIP N  I  K +  Q +QMK KD+RIKLMNEIL+GIK+LKLYAWE SF   I  IR  E  +LR   YL+A+S + W  APFLVAL +F  F      +VL A KAFVSLSLFNIL FP++MLP VI   +QA VSLKR+  FL  DELD E+V+  S   E  V +V+G FSW K +  +L NIN+ VP+GSL+AVVG VG GKTSLISAL+GE+ K+ G++  RGS+ Y+PQQAW +NA+L+DNILF +P +  KY  V+EACALT DL+VLP GD TEIGEKGINLSGGQ+QR+SLARA+Y +  VYLLDDPLSAVD+HV KHIFD VIGP G L  KTRILVTHG+++LP+V+ I V+ DG VSE G++ +LL+ NG+FAEF+R Y
Sbjct:    4 LCGPDKPFWELNLTLYG---QQPDLPECFQMSVLSWAPCIYLWAAAPLYILHLRRNNRGYIMMSILNRIK------TVLGLILWIVCWTDLFSAFHQMNQGSKIS---------PIYFVTPLIVGMTMLLATFLIQFERLKGVQSSGVLFIFWTLSVVFAIVPFRSKIMHANTEVKDKLRFTTFYIYFSFTLLELILSCF-------------------NEKPPLFSSAVMDPNV------CPETTAGFLSRMTFWWFTRMAIKGYKSPLENKDLWSLNKNDSSELVVPGLLNQWEVEKSKAHSSD-DQNVKEQVTFTKPGSGAESNHVNESPEEAEVLLSKQQQKSRQPSFLWALLRAFGPYFLIGSAFKLLQDLITFINPQLLRMLIAFTKQSDVPSWWGYALAFLMFGTSLLQTLILHQHFQYCFVTGMRLRTGIIGAIYRKALVITNEAKRSSTVGEVVNLMSVDAQRFMDLTTFLNMLWSAPLQIFLALFFLWQNLGPSVLAGVAVMVLLIPFNAFIAMKTRTYQVEQMKYKDDRIKLMNEILNGIKVLKLYAWEPSFRDKILQIRQKELHVLRKTAYLSALSTMAWTSAPFLVALTSFAVFVNVDEKNVLDAEKAFVSLSLFNILRFPLNMLPQVISSIVQASVSLKRLQDFLNHDELDPESVDRKSNTTEYAVSVVNGKFSWAKRDQVILDNINVLVPQGSLLAVVGHVGCGKTSLISALLGEMEKLDGQISIRGSVAYVPQQAWIQNATLRDNILFGRPYVEQKYRCVLEACALTPDLEVLPGGDLTEIGEKGINLSGGQRQRVSLARALYSEADVYLLDDPLSAVDAHVAKHIFDHVIGPEGALKGKTRILVTHGISFLPQVNNILVLVDGRVSEMGSYQDLLRQNGAFAEFLRNY 864

HSP 2 Score: 647.121 bits (1668), Expect = 0.000e+0
Identity = 315/581 (54.22%), Postives = 418/581 (71.94%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            E G VK  V+  Y+++   L +  + F Y      ++GAN +LS WT     N TQ  +     +G+Y +LG  Q + ++  +F LA G   A++ LH +LL+N  + P SFFDTTP GRI+NR  KDI  VD  +P+T+ ++L T    + ++ VI  S+P F   + PL  +Y+  QRFY+ TSRQLKR++S+ RSPIYSHF ESI G S IRAY  +  F+   D   DENQ ++YP IVS RWL   +E IGN ++L + + AV  +  +  G  GLS+SYALQ+T  LN+MVRMTSDLES+ VAVER+KEY+E ++EAPW + E +   DWP  G VEFV+YSVRYR GLDLVL+N+++ V  GEK+GIVGRTGAGKSS+ L LFRL+E A G I+ID+  I+++GLHDLRSK+TIIPQ+P+LFSGT+RMNLDPF ++SD E+W  LE+S+L+ F+   +  L+   SEGGENLSVGQ+QLVCLARALL+K+++LVLDEATAAVDLETDDLIQS+IR +F+ CTV TIAHRLNTIMDY RV+VL++G++ E D+P NL+ N+K +F  MA DAGLA
Sbjct:  961 ETGRVKLQVYWEYVKAIGPLLALFICFLYGCQSAAAIGANFWLSEWTNDALHNRTQ--EMLQTRVGVYAALGISQGILVMFSSFTLALGKIQAARKLHQVLLENKFQTPQSFFDTTPTGRIINRFSKDIYVVDEVLPSTLLMFLGTFFASLSTMIVIISSTPVFAFVIAPLALIYFFVQRFYVATSRQLKRLESVSRSPIYSHFSESITGTSVIRAYGRNAAFVLMSDNKVDENQKSYYPGIVSNRWLGVRIEFIGNCIVLFAALFAVTGKDKLSPGLVGLSVSYALQVTMSLNWMVRMTSDLESNIVAVERVKEYSETQTEAPWEVLEKKPPPDWPPLGNVEFVDYSVRYREGLDLVLKNISLKVRGGEKIGIVGRTGAGKSSMTLCLFRLLEAAAGEIVIDDVKISEIGLHDLRSKLTIIPQEPVLFSGTLRMNLDPFERYSDEEVWKALELSHLQKFVTNQAAKLELECSEGGENLSVGQRQLVCLARALLRKTRILVLDEATAAVDLETDDLIQSTIRTEFQDCTVFTIAHRLNTIMDYTRVLVLDKGQIAEFDTPTNLM-NQKGLFFGMAKDAGLA 1538

HSP 3 Score: 91.6633 bits (226), Expect = 6.094e-18
Identity = 73/275 (26.55%), Postives = 130/275 (47.27%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            LN + ++ S +   +V+++R++++   +   P +++     +++     V  VN    +     ++L N+N++V  G  L +VG  G GK+SL  AL   +E  +G I I             R  +  +PQ   + + T+R N+     + + +   VLE   L   +     G    + E G NLS GQ+Q V LARAL  ++ V +LD+  +AVD      I   +       K  T + + H ++ +   + ++VL  GRV E+ S Q+LL
Sbjct:  594 LNMLPQVISSIVQASVSLKRLQDFLNHDELDPESVDRKSNTTEYA----VSVVNGKFSWAKRDQVILDNINVLVPQGSLLAVVGHVGCGKTSLISALLGEMEKLDGQISI-------------RGSVAYVPQQAWIQNATLRDNILFGRPYVEQKYRCVLEACALTPDLEVLPGGDLTEIGEKGINLSGGQRQRVSLARALYSEADVYLLDDPLSAVDAHVAKHIFDHVIGPEGALKGKTRILVTHGISFLPQVNNILVLVDGRVSEMGSYQDLL 851

HSP 4 Score: 74.7146 bits (182), Expect = 1.072e-12
Identity = 68/269 (25.28%), Postives = 119/269 (44.24%), Query Frame = 2 
Query: 1955 VSLKRINKFL-VGDELDTENVEVSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVL---PAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            V+++R+ ++     E   E +E  PP + P    V+ VD +  + +    VL NI+++V  G  + +VG  G+GK+S+   L   L   +G ++              R  +  IPQ+    + +L+ N+    P   +    V +A  L+   K +    A  + E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T   + H L  +    ++ V+  G ++E  T T L+   G F
Sbjct: 1266 VAVERVKEYSETQTEAPWEVLEKKPPPDWPPLGNVEFVDYSVRYREGLDLVLKNISLKVRGGEKIGIVGRTGAGKSSMTLCLFRLLEAAAGEIVIDDVKISEIGLHDLRSKLTIIPQEPVLFSGTLRMNL---DPFERYSDEEVWKALELSHLQKFVTNQAAKLELECSEGGENLSVGQRQLVCLARALLRKTRILVLDEATAAVDLETDDLIQSTI---RTEFQDCTVFTIAHRLNTIMDYTRVLVLDKGQIAEFDTPTNLMNQKGLF 1528
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Zebrafish
Match: abcc6a (ATP-binding cassette, sub-family C (CFTR/MRP), member 6a [Source:ZFIN;Acc:ZDB-GENE-050517-18])

HSP 1 Score: 671.774 bits (1732), Expect = 0.000e+0
Identity = 376/883 (42.58%), Postives = 525/883 (59.46%), Query Frame = 2 
Query:  101 WNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNI-----FKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRL--KFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFK-VAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENV--EVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            W T  P+++ CFQ T+L W P ++LW+    Y   L+         RG+  +      K  L  F+  F  + F   + E    ++      L PI+ +++ +L + +      +G  SS  LFF+WLL +L SI  ++++ +    +    D+ R +     F L      L+CFAD A                         P  K +  N   CP    SFLSK+ F W +GL+ KGYR PL  +DL++LRE DT + I++++E +W         T  R KL++Q    S    L S       D  Q     ++++      LR L  + G PY L G    + +D+  F+ PQ+L L + F+ + +  +W G+  A  +FL+S ++SV   QY + C+  GMR +TAV+G++YRK+L ++S++R+  TVGEIVNL+S D+QKL D   + + +W API + + ++FLWQ LGPS LAG+A +I + P+NG I  K  KLQ  QMK  D R+KLMNEIL+GIKILK YAWE +F + +   R  E + L+ +  L +VS  ++  + FL+A   F  + L    +VL A K FVS++L NIL  P+S LP  +   +QA VSLKR+ KFL  DEL  +NV  E    D   V   +GTFSW K   P L  I+++VP GSLVAVVG VGSGK+SL+SA++GE  K SG V  +GSI Y+PQQAW +NASLQDNILF +      Y RV+EACAL  DL  LPAGD TEIGEKG+NLSGGQKQR+SLARAVY+   VYLLDDPLSAVD+HVG+HIF++VIGP G+L  KTR+LVTHG+++LP+ D I V+ DG +SE G++ ELL  NG+FA+FI T+
Sbjct:   20 WYTHRPELSNCFQNTVLVWAPCIYLWVLSPFYCLHLY------CHGRGRLPLSSLCNAKLLLGFFLASFGFVEFFYILLERRLEIHQHLVFLLSPIMRSLTVVLAVCVIHWERVRGCRSSVFLFFFWLLGVLCSIIPLHAKVQLAVEQGLSPDIVRYLAFFSYFALQLAQLFLSCFADQA-------------------------PLGKAVHKN--ACPVQDASFLSKILFWWFSGLIFKGYRSPLQAEDLWSLREEDTSERIISDLEEEW---------TAKRTKLQQQENHMSTSAALGSRLP----DQAQLLRKIQKEQSSGFCLLRTLARSFG-PYFLTGTLCLIVHDVFMFSVPQVLSLLLGFMKDEDTPLWKGYFYATLMFLLSCLQSVFNHQYTYTCFTVGMRVKTAVMGLVYRKSLVMNSSARRTCTVGEIVNLVSADTQKLMDFVVYFNAVWLAPIEVTLCLFFLWQHLGPSALAGIATVIFIFPLNGFIARKRSKLQEIQMKYMDGRVKLMNEILNGIKILKFYAWEKAFLEQVLGYREKELKTLKKSQILYSVSLASFNSSSFLIAFAMFGVYVLIDDKNVLDAQKIFVSMALINILKTPLSQLPFAMSTTMQALVSLKRLGKFLCQDELKPDNVARESFKSDVDGVVFDNGTFSWSKDGPPCLKRISVKVPCGSLVAVVGHVGSGKSSLLSAMLGETEKRSGTVSVKGSIAYVPQQAWIQNASLQDNILFGREKKESWYQRVLEACALLPDLDNLPAGDATEIGEKGLNLSGGQKQRVSLARAVYRKGDVYLLDDPLSAVDAHVGQHIFNKVIGPKGILRDKTRVLVTHGMSFLPQADLILVLVDGEISERGSYQELLNRNGAFADFIHTF 855

HSP 2 Score: 570.081 bits (1468), Expect = 1.067e-175
Identity = 278/582 (47.77%), Postives = 409/582 (70.27%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQ-NPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A IG VK  +++ Y R+       ++VF YA     S+  N +LS W +    NGTQ N D +   LG+YG+LG  Q + I     A++ G  +AS+ LH  LL N+L +P SFF++TP G +LNR  K+ID +D  IP  +++ L     +     ++ +++P+  + ++P+  +Y   Q FY+ TS QL+R++S+ RSPIY+H  E++ GAS IRA+     FI   +   D NQ A++P  ++ RWL   LE +GN ++L + +L+V+ + T+  G  GL++S++LQ+TG L+++VR  +D+E++ V+VER+KEYA+   EA W+IE S     WP +G +EF +Y ++YR GL+L L+ +++ +   EK+GIVGRTGAGKSSLAL +FR++E A+G I ID  +I ++GLHDLRS+ITIIPQDP+LFSG++RMNLDPFN +SD E+W+ LE+++LK+F+++  + L +  SEGGENLS+GQ+QLVCLARALL+K+KVLVLDEATAA+DLETD LIQS+IR QF+ C VLTIAHRLNTIMDY +V+V+++G V E+DSP NL+A ++  F+ M  +AGL
Sbjct:  929 ARIGRVKLEMYIEYFRTIGLPLIISIVFLYAFQQAASLSNNYWLSLWADQPVINGTQLNTDLK---LGVYGALGFAQGISIFGTTVAISLGCIIASRHLHLDLLNNVLHSPMSFFESTPSGNLLNRFAKEIDAIDNMIPDGLKMMLSYFFKLTEVCIIVLMATPFAAVIILPMVFLYGFIQSFYVATSCQLRRLESVSRSPIYTHLNETVQGASVIRAFNEQSRFIMGANHKVDHNQTAYFPRFIATRWLGVNLEFLGNGIVLAASILSVMAKGTLSPGMVGLAVSHSLQVTGFLSWIVRSWTDVENNIVSVERVKEYADTPKEAAWSIEGSSLPPSWPQTGTIEFQDYGLQYRKGLELALKGISVHIHEREKIGIVGRTGAGKSSLALGIFRILEAAKGEIYIDGINIAEIGLHDLRSRITIIPQDPVLFSGSLRMNLDPFNAYSDEEVWNALELAHLKNFVSELPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKVLVLDEATAALDLETDTLIQSTIRSQFEDCAVLTIAHRLNTIMDYTKVIVMDKGHVVEMDSPSNLIA-KRGQFYYMCREAGL 1506

HSP 3 Score: 75.8702 bits (185), Expect = 3.975e-13
Identity = 66/260 (25.38%), Postives = 115/260 (44.23%), Query Frame = 2 
Query: 3926 VAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            V+++R+ ++   +   P N+      SD      V F N +  +       L+ +++ V  G  + +VG  G+GKSSL  A+    E   GT+              ++  I  +PQ   + + +++ N+    +  +     VLE   L   +     G    + E G NLS GQKQ V LARA+ +K  V +LD+  +AVD      I + +   +   +  T + + H ++ +   D ++VL  G + E  S Q LL
Sbjct:  599 VSLKRLGKFLCQDELKPDNVARESFKSD---VDGVVFDNGTFSWSKDGPPCLKRISVKVPCGSLVAVVGHVGSGKSSLLSAMLGETEKRSGTV-------------SVKGSIAYVPQQAWIQNASLQDNILFGREKKESWYQRVLEACALLPDLDNLPAGDATEIGEKGLNLSGGQKQRVSLARAVYRKGDVYLLDDPLSAVDAHVGQHIFNKVIGPKGILRDKTRVLVTHGMSFLPQADLILVLVDGEISERGSYQELL 842

HSP 4 Score: 64.6994 bits (156), Expect = 1.115e-9
Identity = 66/271 (24.35%), Postives = 110/271 (40.59%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVEVSP-----PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSL-------ISALIGELY------KVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIR 2713
            VS++R+ ++    +    ++E S      P    ++  D    + K     L  I++ + E   + +VG  G+GK+SL       + A  GE+Y         G    R  I  IPQ     + SL+ N+       + +    +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   V +LD+  +A+D      I   +            + + H L  +    K+ VM  G+V E  + + L+   G F    R
Sbjct: 1235 VSVERVKEYADTPKEAAWSIEGSSLPPSWPQTGTIEFQDYGLQYRKGLELALKGISVHIHEREKIGIVGRTGAGKSSLALGIFRILEAAKGEIYIDGINIAEIGLHDLRSRITIIPQDPVLFSGSLRMNLDPFNAYSDEEVWNALELAHLKNFVSELPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKVLVLDEATAALDLETDTLIQSTI---RSQFEDCAVLTIAHRLNTIMDYTKVIVMDKGHVVEMDSPSNLIAKRGQFYYMCR 1502
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Xenopus
Match: septin9 (septin 9 [Source:Xenbase;Acc:XB-GENE-1012202])

HSP 1 Score: 783.482 bits (2022), Expect = 0.000e+0
Identity = 417/886 (47.07%), Postives = 567/886 (64.00%), Query Frame = 2 
Query:  107 TQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISES-------ISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRY----RRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTK--FRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENV--EVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            T +PD+T CFQ T+L WIP ++LW++   Y+  L       Y  RG   I  S L      F +L +C   ++        + N  PPP  ++ P++  I+ I    L +    +G+ SSGVL  +W L  + +I    S+     R+ +  D+  FR  T    F L+ +  +L+CF                    E +P  S + D+    IN  PCPE+   FLS+LTF W T + I GY++PL  KDL++L E+DT + +VTN+  +W +E   + Q +  + KK E       N+   K+ E +  I           +K K PSFL+ L  T G  +++   FK+  DLL+F  PQ+L + ITFI N +   W GF +A+ +FL S+++++I  Q++  C+VTGMR R+A+ GIIYRK+L +++++++ +TVGE+VNLMSVD+Q+ QD+ +FL++LW+AP+ I +A+YFLWQ LGPSVLAGVA+M+ LIPIN  I  K +  Q +QM+ KD+RIKLMNEIL+GIK+LKLYAWE SF Q +  IRN E  IL+ A YLNA+S   W  APFLVAL TF  +      ++L A KAFVSLSLFNIL FP++MLP VI    QA VS+KRI  FL  DELD   V  + + P    + + +GTFSW K    +L NIN+ VP GSLVAVVG VG GK+SL+SAL+GE+ K  G V  RGS+ Y+PQQAW +N +L+DNILF +      Y +V+EACAL  DL+VLP GDQTEIGEKGINLSGGQKQR+SLARAV+ +  VYLLDDPLSAVD+HV KHIFD VIGP GLL  KTR+LVTHG+++LP+VD I V+ DG V+E G++ ELLK NG+F+EF+R Y
Sbjct:   23 TDNPDVTPCFQNTVLAWIPCVYLWVALPFYLLYL------KYNRRGY--IVLSMLSKAKTVFGVLLWCVCWADLFYSFHGLVQNQSPPPVYFVTPLILGITMITATVLAQYERLRGVQSSGVLIIFWFLATVCAIIPFRSKVMASARQGQVTDK--FRFTTFFLYFSLLVIELLLSCF-------------------KEARPFFSPVRDE----IN--PCPESDAGFLSRLTFWWFTKMAILGYKRPLEDKDLWSLNEDDTSNVVVTNLIKEWEKEKSNLAQMQVSYSKKPEA----VLNHTDEKAYESDVLI--------VDNKKPKEPSFLKVLLRTFGPYFLIGSFFKLFQDLLSFVNPQLLSILITFIKNKDAPSWWGFCIAVLMFLTSLVQTLILHQHFQYCFVTGMRLRSAITGIIYRKSLVITNSAKRSSTVGEVVNLMSVDAQRFQDLTTFLNMLWSAPLQICLALYFLWQALGPSVLAGVAVMVLLIPINAFIAMKTRAFQVEQMQYKDSRIKLMNEILNGIKVLKLYAWEPSFAQKVLEIRNKELNILKKAAYLNALSTFAWTSAPFLVALTTFAVYVTVDEKNILDAEKAFVSLSLFNILRFPLNMLPQVISNLAQASVSIKRIQNFLANDELDLNAVTKDKTLPG-NAITVHNGTFSWAKNGGAILQNINLLVPSGSLVAVVGQVGCGKSSLVSALLGEMEKEEGEVSVRGSVAYVPQQAWIQNCTLKDNILFGRAANEKNYKKVLEACALVTDLEVLPGGDQTEIGEKGINLSGGQKQRVSLARAVFSNADVYLLDDPLSAVDAHVAKHIFDNVIGPDGLLRGKTRVLVTHGISFLPQVDHIVVLVDGRVTEMGSYQELLKQNGAFSEFLRNY 860

HSP 2 Score: 660.988 bits (1704), Expect = 0.000e+0
Identity = 324/579 (55.96%), Postives = 423/579 (73.06%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAG 4741
            E G VK +VF  Y+++     S  + F Y+     ++GAN++LS WT     N TQ   +    +G+Y +LG  Q L ++  +F+LA     A++ LH+ LL N +  P SF+DTTP+GRI+NR  KDI  +D  IP TI ++L T    + ++ VI  S+P F + ++PL   Y   QRFY+ TSRQLKR++S+ RSPIYSHF E+I GAS IRAY   + FI   D   DENQ ++YP IVS RWL   +E +GN V+L + + AV+ R  +  G  GLS+SYALQ+T  LN+MVRMTSDLE++ VAVER+KEYAE E+EAPW+IE+++   DWP  G VE  NYSVRYR GLDLVL+NLN+ V+ GEK+GIVGRTGAGKSS+ L LFR++EPAEG + IDN +I+++GL DLRS++TIIPQDP+LFSGT+RMNLDPFN++SD E+W  LE+S LK F+A     L+Y  SEGGENLSVGQ+QLVCLARALL+K+++L+LDEATAA+DLETDDLIQ +IR QF+ CTVLTIAHRLNTIMDY RV+VL++GR+ E D+P NL+A  K IF+ MA DAG
Sbjct:  954 ETGRVKMTVFWQYMKAVGLAISVFICFLYSCQNAAAIGANVWLSDWTNEPVINQTQQ--NTQMRVGVYAALGILQGLLVMTSSFSLAIAGIGAARKLHSALLDNKMHTPQSFYDTTPIGRIINRFSKDIYVIDEVIPGTILMFLATFFTSLSTMIVIVASTPLFAVVIIPLAIAYIFVQRFYVATSRQLKRLESVSRSPIYSHFSETITGASIIRAYGRQNSFIVLSDNKVDENQKSYYPGIVSNRWLGVRVEFVGNCVVLFAALFAVLGREHLSPGLVGLSVSYALQVTMSLNWMVRMTSDLETNIVAVERVKEYAENETEAPWHIEDTKPPEDWPSKGEVELSNYSVRYRAGLDLVLKNLNLKVNGGEKVGIVGRTGAGKSSMTLCLFRILEPAEGIVKIDNVNISEIGLQDLRSRLTIIPQDPVLFSGTLRMNLDPFNKYSDDEIWKALELSNLKKFVAGQPSQLEYECSEGGENLSVGQRQLVCLARALLRKTRILILDEATAAIDLETDDLIQMTIRTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGRIAEFDTPTNLIA-LKGIFYGMAKDAG 1529

HSP 3 Score: 88.5817 bits (218), Expect = 8.258e-17
Identity = 72/275 (26.18%), Postives = 129/275 (46.91%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            LN + ++ S+L   +V+++RI+ +    +    ++         P +  +   N +  +      +L+N+N++V +G  + +VG+ G GKSSL  AL   +E  EG +              +R  +  +PQ   + + T++ N+      ++     VLE   L + +     G Q  + E G NLS GQKQ V LARA+   + V +LD+  +AVD      I  ++       +  T + + H ++ +   D ++VL  GRV E+ S Q LL
Sbjct:  590 LNMLPQVISNLAQASVSIKRIQNFL---ANDELDLNAVTKDKTLPGNA-ITVHNGTFSWAKNGGAILQNINLLVPSGSLVAVVGQVGCGKSSLVSALLGEMEKEEGEV-------------SVRGSVAYVPQQAWIQNCTLKDNILFGRAANEKNYKKVLEACALVTDLEVLPGGDQTEIGEKGINLSGGQKQRVSLARAVFSNADVYLLDDPLSAVDAHVAKHIFDNVIGPDGLLRGKTRVLVTHGISFLPQVDHIVVLVDGRVTEMGSYQELL 847

HSP 4 Score: 67.781 bits (164), Expect = 2.035e-10
Identity = 66/270 (24.44%), Postives = 120/270 (44.44%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVE-VSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGD----QTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            V+++R+ ++   +     ++E   PP++ P    V++ + +  +      VL N+N++V  G  V +VG  G+GK+S+   L   L    G V               R  +  IPQ     + +L+ N+    P   +  + + +A  L+ +LK   AG     + E  E G NLS GQ+Q + LARA+ +   + +LD+  +A+D      I   +          T + + H L  +    ++ V+  G ++E  T T L+   G F
Sbjct: 1259 VAVERVKEYAENETEAPWHIEDTKPPEDWPSKGEVELSNYSVRYRAGLDLVLKNLNLKVNGGEKVGIVGRTGAGKSSMTLCLFRILEPAEGIVKIDNVNISEIGLQDLRSRLTIIPQDPVLFSGTLRMNL---DPFNKYSDDEIWKALELS-NLKKFVAGQPSQLEYECSEGGENLSVGQRQLVCLARALLRKTRILILDEATAAIDLETDDLIQMTI---RTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGRIAEFDTPTNLIALKGIF 1521
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Xenopus
Match: septin9 (septin 9 [Source:Xenbase;Acc:XB-GENE-1012202])

HSP 1 Score: 767.689 bits (1981), Expect = 0.000e+0
Identity = 411/884 (46.49%), Postives = 562/884 (63.57%), Query Frame = 2 
Query:  107 TQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISES-------ISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRY----RRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENV--EVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            T +PD+T CFQ T+L WIP ++LW++   Y+  L+ K    Y  RG   I  S L      F +L +C   ++        + N  PPP  ++ P++  I+ I    L +    +G+ SSGVL  +W L  + +I    S+     R+ +  D+  FR  T    F L+ +  +L+CF                    E +P  S + D+    IN  PCPE+   FLS+LTF W T + I GY++PL  KDL++L E+DT + +VTN+  +W +E   + Q  + KK E       N+   K+ E +  I           +K K PSFL+ L  T G  +++   FK+  DLL+F  PQ+L + ITFI N +   W GF +A+ +FL S+++++I  Q++  C+VTGMR R+A+ GIIYRK+L +++++++ +TVGE+VNLMSVD+Q+ QD+ +FL++LW+AP+ I +A+YFLWQ LGPSVLAGVA+M+ LIPIN  I  K +  Q +QM+ KD+RIKLMNEIL+GIK+LKLYAWE SF Q +  IRN E  IL+ A YLNA+S   W  APFLVAL TF  +      ++L A KAFVSLSLFNIL FP++MLP VI    QA VS+KRI  FL  DELD   V  + + P +      D  ++        + +IN+ VP GSLVAVVG VG GK+SL+SAL+GE+ K  G V  RGS+ Y+PQQAW +N +L+DNILF +      Y +V+EACAL  DL+VLP GDQTEIGEKGINLSGGQKQR+SLARAV+ +  VYLLDDPLSAVD+HV KHIFD VIGP GLL  KTR+LVTHG+++LP+VD I V+ DG V+E G++ ELLK NG+F+EF+R Y
Sbjct:   43 TDNPDVTPCFQNTVLAWIPCVYLWVALPFYL--LYLK----YNRRGY--IVLSMLSKAKTVFGVLLWCVCWADLFYSFHGLVQNQSPPPVYFVTPLILGITMITATVLAQYERLRGVQSSGVLIIFWFLATVCAIIPFRSKVMASARQGQVTDK--FRFTTFFLYFSLLVIELLLSCF-------------------KEARPFFSPVRDE----IN--PCPESDAGFLSRLTFWWFTKMAILGYKRPLEDKDLWSLNEDDTSNVVVTNLIKEWEKEKSNLMQVSYSKKPEA----VLNHTDEKAYESDVLI--------VDNKKPKEPSFLKVLLRTFGPYFLIGSFFKLFQDLLSFVNPQLLSILITFIKNKDAPSWWGFCIAVLMFLTSLVQTLILHQHFQYCFVTGMRLRSAITGIIYRKSLVITNSAKRSSTVGEVVNLMSVDAQRFQDLTTFLNMLWSAPLQICLALYFLWQALGPSVLAGVAVMVLLIPINAFIAMKTRAFQVEQMQYKDSRIKLMNEILNGIKVLKLYAWEPSFAQKVLEIRNKELNILKKAAYLNALSTFAWTSAPFLVALTTFAVYVTVDEKNILDAEKAFVSLSLFNILRFPLNMLPQVISNLAQASVSIKRIQNFLANDELDLNAVTKDKTLPGKDEGNCSDLNYTLHFKPFCFIHSINLLVPSGSLVAVVGQVGCGKSSLVSALLGEMEKEEGEVSVRGSVAYVPQQAWIQNCTLKDNILFGRAANEKNYKKVLEACALVTDLEVLPGGDQTEIGEKGINLSGGQKQRVSLARAVFSNADVYLLDDPLSAVDAHVAKHIFDNVIGPDGLLRGKTRVLVTHGISFLPQVDHIVVLVDGRVTEMGSYQELLKQNGAFSEFLRNY 879

HSP 2 Score: 664.455 bits (1713), Expect = 0.000e+0
Identity = 326/581 (56.11%), Postives = 425/581 (73.15%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            E G VK +VF  Y+++     S  + F Y+     ++GAN++LS WT     N TQ   +    +G+Y +LG  Q L ++  +F+LA     A++ LH+ LL N +  P SF+DTTP+GRI+NR  KDI  +D  IP TI ++L T    + ++ VI  S+P F + ++PL   Y   QRFY+ TSRQLKR++S+ RSPIYSHF E+I GAS IRAY   + FI   D   DENQ ++YP IVS RWL   +E +GN V+L + + AV+ R  +  G  GLS+SYALQ+T  LN+MVRMTSDLE++ VAVER+KEYAE E+EAPW+IE+++   DWP  G VE  NYSVRYR GLDLVL+NLN+ V+ GEK+GIVGRTGAGKSS+ L LFR++EPAEG + IDN +I+++GL DLRS++TIIPQDP+LFSGT+RMNLDPFN++SD E+W  LE+S LK F+A     L+Y  SEGGENLSVGQ+QLVCLARALL+K+++L+LDEATAA+DLETDDLIQ +IR QF+ CTVLTIAHRLNTIMDY RV+VL++GR+ E D+P NL+A  K IF+ MA DAGLA
Sbjct:  967 ETGRVKMTVFWQYMKAVGLAISVFICFLYSCQNAAAIGANVWLSDWTNEPVINQTQQ--NTQMRVGVYAALGILQGLLVMTSSFSLAIAGIGAARKLHSALLDNKMHTPQSFYDTTPIGRIINRFSKDIYVIDEVIPGTILMFLATFFTSLSTMIVIVASTPLFAVVIIPLAIAYIFVQRFYVATSRQLKRLESVSRSPIYSHFSETITGASIIRAYGRQNSFIVLSDNKVDENQKSYYPGIVSNRWLGVRVEFVGNCVVLFAALFAVLGREHLSPGLVGLSVSYALQVTMSLNWMVRMTSDLETNIVAVERVKEYAENETEAPWHIEDTKPPEDWPSKGEVELSNYSVRYRAGLDLVLKNLNLKVNGGEKVGIVGRTGAGKSSMTLCLFRILEPAEGIVKIDNVNISEIGLQDLRSRLTIIPQDPVLFSGTLRMNLDPFNKYSDDEIWKALELSNLKKFVAGQPSQLEYECSEGGENLSVGQRQLVCLARALLRKTRILILDEATAAIDLETDDLIQMTIRTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGRIAEFDTPTNLIA-LKGIFYGMAKDAGLA 1544

HSP 3 Score: 95.9005 bits (237), Expect = 5.137e-19
Identity = 75/275 (27.27%), Postives = 130/275 (47.27%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            LN + ++ S+L   +V+++RI+ +     E   N           D G    +NY++ ++P     + ++N++V +G  + +VG+ G GKSSL  AL   +E  EG +              +R  +  +PQ   + + T++ N+      ++     VLE   L + +     G Q  + E G NLS GQKQ V LARA+   + V +LD+  +AVD      I  ++       +  T + + H ++ +   D ++VL  GRV E+ S Q LL
Sbjct:  608 LNMLPQVISNLAQASVSIKRIQNFLA-NDELDLNAVTKDKTLPGKDEGNCSDLNYTLHFKPFC--FIHSINLLVPSGSLVAVVGQVGCGKSSLVSALLGEMEKEEGEV-------------SVRGSVAYVPQQAWIQNCTLKDNILFGRAANEKNYKKVLEACALVTDLEVLPGGDQTEIGEKGINLSGGQKQRVSLARAVFSNADVYLLDDPLSAVDAHVAKHIFDNVIGPDGLLRGKTRVLVTHGISFLPQVDHIVVLVDGRVTEMGSYQELL 866

HSP 4 Score: 68.1662 bits (165), Expect = 1.505e-10
Identity = 66/270 (24.44%), Postives = 120/270 (44.44%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVE-VSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGD----QTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            V+++R+ ++   +     ++E   PP++ P    V++ + +  +      VL N+N++V  G  V +VG  G+GK+S+   L   L    G V               R  +  IPQ     + +L+ N+    P   +  + + +A  L+ +LK   AG     + E  E G NLS GQ+Q + LARA+ +   + +LD+  +A+D      I   +          T + + H L  +    ++ V+  G ++E  T T L+   G F
Sbjct: 1272 VAVERVKEYAENETEAPWHIEDTKPPEDWPSKGEVELSNYSVRYRAGLDLVLKNLNLKVNGGEKVGIVGRTGAGKSSMTLCLFRILEPAEGIVKIDNVNISEIGLQDLRSRLTIIPQDPVLFSGTLRMNL---DPFNKYSDDEIWKALELS-NLKKFVAGQPSQLEYECSEGGENLSVGQRQLVCLARALLRKTRILILDEATAAIDLETDDLIQMTI---RTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGRIAEFDTPTNLIALKGIF 1534
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Xenopus
Match: septin9 (septin 9 [Source:Xenbase;Acc:XB-GENE-1012202])

HSP 1 Score: 767.689 bits (1981), Expect = 0.000e+0
Identity = 413/884 (46.72%), Postives = 561/884 (63.46%), Query Frame = 2 
Query:  107 TQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISES-------ISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRY----RRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVL--ININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            T +PD+T CFQ T+L WIP ++LW++   Y+  L+ K    Y  RG   I  S L      F +L +C   ++        + N  PPP  ++ P++  I+ I    L +    +G+ SSGVL  +W L  + +I    S+     R+ +  D+  FR  T    F L+ +  +L+CF                    E +P  S + D+    IN  PCPE+   FLS+LTF W T + I GY++PL  KDL++L E+DT + +VTN+  +W +E   + Q  + KK E       N+   K+ E +  I           +K K PSFL+ L  T G  +++   FK+  DLL+F  PQ+L + ITFI N +   W GF +A+ +FL S+++++I  Q++  C+VTGMR R+A+ GIIYRK+L +++++++ +TVGE+VNLMSVD+Q+ QD+ +FL++LW+AP+ I +A+YFLWQ LGPSVLAGVA+M+ LIPIN  I  K +  Q +QM+ KD+RIKLMNEIL+GIK+LKLYAWE SF Q +  IRN E  IL+ A YLNA+S   W  APFLVAL TF  +      ++L A KAFVSLSLFNIL FP++MLP VI    QA VS+KRI  FL  DELD   V          K + G      ++  V+   NIN+ VP GSLVAVVG VG GK+SL+SAL+GE+ K  G V  RGS+ Y+PQQAW +N +L+DNILF +      Y +V+EACAL  DL+VLP GDQTEIGEKGINLSGGQKQR+SLARAV+ +  VYLLDDPLSAVD+HV KHIFD VIGP GLL  KTR+LVTHG+++LP+VD I V+ DG V+E G++ ELLK NG+F+EF+R Y
Sbjct:   14 TDNPDVTPCFQNTVLAWIPCVYLWVALPFYL--LYLK----YNRRGY--IVLSMLSKAKTVFGVLLWCVCWADLFYSFHGLVQNQSPPPVYFVTPLILGITMITATVLAQYERLRGVQSSGVLIIFWFLATVCAIIPFRSKVMASARQGQVTDK--FRFTTFFLYFSLLVIELLLSCF-------------------KEARPFFSPVRDE----IN--PCPESDAGFLSRLTFWWFTKMAILGYKRPLEDKDLWSLNEDDTSNVVVTNLIKEWEKEKSNLMQVSYSKKPEA----VLNHTDEKAYESDVLI--------VDNKKPKEPSFLKVLLRTFGPYFLIGSFFKLFQDLLSFVNPQLLSILITFIKNKDAPSWWGFCIAVLMFLTSLVQTLILHQHFQYCFVTGMRLRSAITGIIYRKSLVITNSAKRSSTVGEVVNLMSVDAQRFQDLTTFLNMLWSAPLQICLALYFLWQALGPSVLAGVAVMVLLIPINAFIAMKTRAFQVEQMQYKDSRIKLMNEILNGIKVLKLYAWEPSFAQKVLEIRNKELNILKKAAYLNALSTFAWTSAPFLVALTTFAVYVTVDEKNILDAEKAFVSLSLFNILRFPLNMLPQVISNLAQASVSIKRIQNFLANDELDLNAVTKD-------KTLPGKDEGNCSDLNVIKCYNINLLVPSGSLVAVVGQVGCGKSSLVSALLGEMEKEEGEVSVRGSVAYVPQQAWIQNCTLKDNILFGRAANEKNYKKVLEACALVTDLEVLPGGDQTEIGEKGINLSGGQKQRVSLARAVFSNADVYLLDDPLSAVDAHVAKHIFDNVIGPDGLLRGKTRVLVTHGISFLPQVDHIVVLVDGRVTEMGSYQELLKQNGAFSEFLRNY 843

HSP 2 Score: 664.455 bits (1713), Expect = 0.000e+0
Identity = 326/581 (56.11%), Postives = 425/581 (73.15%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            E G VK +VF  Y+++     S  + F Y+     ++GAN++LS WT     N TQ   +    +G+Y +LG  Q L ++  +F+LA     A++ LH+ LL N +  P SF+DTTP+GRI+NR  KDI  +D  IP TI ++L T    + ++ VI  S+P F + ++PL   Y   QRFY+ TSRQLKR++S+ RSPIYSHF E+I GAS IRAY   + FI   D   DENQ ++YP IVS RWL   +E +GN V+L + + AV+ R  +  G  GLS+SYALQ+T  LN+MVRMTSDLE++ VAVER+KEYAE E+EAPW+IE+++   DWP  G VE  NYSVRYR GLDLVL+NLN+ V+ GEK+GIVGRTGAGKSS+ L LFR++EPAEG + IDN +I+++GL DLRS++TIIPQDP+LFSGT+RMNLDPFN++SD E+W  LE+S LK F+A     L+Y  SEGGENLSVGQ+QLVCLARALL+K+++L+LDEATAA+DLETDDLIQ +IR QF+ CTVLTIAHRLNTIMDY RV+VL++GR+ E D+P NL+A  K IF+ MA DAGLA
Sbjct:  937 ETGRVKMTVFWQYMKAVGLAISVFICFLYSCQNAAAIGANVWLSDWTNEPVINQTQQ--NTQMRVGVYAALGILQGLLVMTSSFSLAIAGIGAARKLHSALLDNKMHTPQSFYDTTPIGRIINRFSKDIYVIDEVIPGTILMFLATFFTSLSTMIVIVASTPLFAVVIIPLAIAYIFVQRFYVATSRQLKRLESVSRSPIYSHFSETITGASIIRAYGRQNSFIVLSDNKVDENQKSYYPGIVSNRWLGVRVEFVGNCVVLFAALFAVLGREHLSPGLVGLSVSYALQVTMSLNWMVRMTSDLETNIVAVERVKEYAENETEAPWHIEDTKPPEDWPSKGEVELSNYSVRYRAGLDLVLKNLNLKVNGGEKVGIVGRTGAGKSSMTLCLFRILEPAEGIVKIDNVNISEIGLQDLRSRLTIIPQDPVLFSGTLRMNLDPFNKYSDDEIWKALELSNLKKFVAGQPSQLEYECSEGGENLSVGQRQLVCLARALLRKTRILILDEATAAIDLETDDLIQMTIRTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGRIAEFDTPTNLIA-LKGIFYGMAKDAGLA 1514

HSP 3 Score: 87.0409 bits (214), Expect = 2.552e-16
Identity = 75/275 (27.27%), Postives = 124/275 (45.09%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            LN + ++ S+L   +V+++RI+ +     E   N           D G    +N    Y         N+N++V +G  + +VG+ G GKSSL  AL   +E  EG +              +R  +  +PQ   + + T++ N+      ++     VLE   L + +     G Q  + E G NLS GQKQ V LARA+   + V +LD+  +AVD      I  ++       +  T + + H ++ +   D ++VL  GRV E+ S Q LL
Sbjct:  579 LNMLPQVISNLAQASVSIKRIQNFLA-NDELDLNAVTKDKTLPGKDEGNCSDLNVIKCY---------NINLLVPSGSLVAVVGQVGCGKSSLVSALLGEMEKEEGEV-------------SVRGSVAYVPQQAWIQNCTLKDNILFGRAANEKNYKKVLEACALVTDLEVLPGGDQTEIGEKGINLSGGQKQRVSLARAVFSNADVYLLDDPLSAVDAHVAKHIFDNVIGPDGLLRGKTRVLVTHGISFLPQVDHIVVLVDGRVTEMGSYQELL 830

HSP 4 Score: 67.781 bits (164), Expect = 1.947e-10
Identity = 66/270 (24.44%), Postives = 120/270 (44.44%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVE-VSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGD----QTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            V+++R+ ++   +     ++E   PP++ P    V++ + +  +      VL N+N++V  G  V +VG  G+GK+S+   L   L    G V               R  +  IPQ     + +L+ N+    P   +  + + +A  L+ +LK   AG     + E  E G NLS GQ+Q + LARA+ +   + +LD+  +A+D      I   +          T + + H L  +    ++ V+  G ++E  T T L+   G F
Sbjct: 1242 VAVERVKEYAENETEAPWHIEDTKPPEDWPSKGEVELSNYSVRYRAGLDLVLKNLNLKVNGGEKVGIVGRTGAGKSSMTLCLFRILEPAEGIVKIDNVNISEIGLQDLRSRLTIIPQDPVLFSGTLRMNL---DPFNKYSDDEIWKALELS-NLKKFVAGQPSQLEYECSEGGENLSVGQRQLVCLARALLRKTRILILDEATAAIDLETDDLIQMTI---RTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGRIAEFDTPTNLIALKGIF 1504
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Xenopus
Match: septin9 (septin 9 [Source:Xenbase;Acc:XB-GENE-1012202])

HSP 1 Score: 751.51 bits (1939), Expect = 0.000e+0
Identity = 409/887 (46.11%), Postives = 559/887 (63.02%), Query Frame = 2 
Query:  107 TQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISES-------ISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRY----RRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRI-PCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTK--FRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENV--EVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            T +PD+T CFQ T+L WIP ++LW++   Y+  L+ K    Y  RG   I  S L      F +L +C   ++        + N  PPP  ++ P++  I+ I    L +    +G+ SSGVL  +W L  + +I    S+     R+ +  D+  FR  T    F L+ +  +L+CF                    E +P  S + D+    I RI P  +  V  L+      L       Y++PL  KDL++L E+DT + +VTN+  +W +E   + Q +  + KK E       N+   K+ E +  I           +K K PSFL+ L  T G  +++   FK+  DLL+F  PQ+L + ITFI N +   W GF +A+ +FL S+++++I  Q++  C+VTGMR R+A+ GIIYRK+L +++++++ +TVGE+VNLMSVD+Q+ QD+ +FL++LW+AP+ I +A+YFLWQ LGPSVLAGVA+M+ LIPIN  I  K +  Q +QM+ KD+RIKLMNEIL+GIK+LKLYAWE SF Q +  IRN E  IL+ A YLNA+S   W  APFLVAL TF  +      ++L A KAFVSLSLFNIL FP++MLP VI    QA VS+KRI  FL  DELD   V  + + P    + + +GTFSW K    +L NIN+ VP GSLVAVVG VG GK+SL+SAL+GE+ K  G V  RGS+ Y+PQQAW +N +L+DNILF +      Y +V+EACAL  DL+VLP GDQTEIGEKGINLSGGQKQR+SLARAV+ +  VYLLDDPLSAVD+HV KHIFD VIGP GLL  KTR+LVTHG+++LP+VD I V+ DG V+E G++ ELLK NG+F+EF+R Y
Sbjct:   26 TDNPDVTPCFQNTVLAWIPCVYLWVALPFYL--LYLK----YNRRGY--IVLSMLSKAKTVFGVLLWCVCWADLFYSFHGLVQNQSPPPVYFVTPLILGITMITATVLAQYERLRGVQSSGVLIIFWFLATVCAIIPFRSKVMASARQGQVTDK--FRFTTFFLYFSLLVIELLLSCF-------------------KEARPFFSPVRDE----IVRISPYFKKEVHLLAHTRLALL-----HSYKRPLEDKDLWSLNEDDTSNVVVTNLIKEWEKEKSNLAQMQVSYSKKPEA----VLNHTDEKAYESDVLI--------VDNKKPKEPSFLKVLLRTFGPYFLIGSFFKLFQDLLSFVNPQLLSILITFIKNKDAPSWWGFCIAVLMFLTSLVQTLILHQHFQYCFVTGMRLRSAITGIIYRKSLVITNSAKRSSTVGEVVNLMSVDAQRFQDLTTFLNMLWSAPLQICLALYFLWQALGPSVLAGVAVMVLLIPINAFIAMKTRAFQVEQMQYKDSRIKLMNEILNGIKVLKLYAWEPSFAQKVLEIRNKELNILKKAAYLNALSTFAWTSAPFLVALTTFAVYVTVDEKNILDAEKAFVSLSLFNILRFPLNMLPQVISNLAQASVSIKRIQNFLANDELDLNAVTKDKTLPG-NAITVHNGTFSWAKNGGAILQNINLLVPSGSLVAVVGQVGCGKSSLVSALLGEMEKEEGEVSVRGSVAYVPQQAWIQNCTLKDNILFGRAANEKNYKKVLEACALVTDLEVLPGGDQTEIGEKGINLSGGQKQRVSLARAVFSNADVYLLDDPLSAVDAHVAKHIFDNVIGPDGLLRGKTRVLVTHGISFLPQVDHIVVLVDGRVTEMGSYQELLKQNGAFSEFLRNY 861

HSP 2 Score: 665.226 bits (1715), Expect = 0.000e+0
Identity = 326/581 (56.11%), Postives = 425/581 (73.15%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            E G VK +VF  Y+++     S  + F Y+     ++GAN++LS WT     N TQ   +    +G+Y +LG  Q L ++  +F+LA     A++ LH+ LL N +  P SF+DTTP+GRI+NR  KDI  +D  IP TI ++L T    + ++ VI  S+P F + ++PL   Y   QRFY+ TSRQLKR++S+ RSPIYSHF E+I GAS IRAY   + FI   D   DENQ ++YP IVS RWL   +E +GN V+L + + AV+ R  +  G  GLS+SYALQ+T  LN+MVRMTSDLE++ VAVER+KEYAE E+EAPW+IE+++   DWP  G VE  NYSVRYR GLDLVL+NLN+ V+ GEK+GIVGRTGAGKSS+ L LFR++EPAEG + IDN +I+++GL DLRS++TIIPQDP+LFSGT+RMNLDPFN++SD E+W  LE+S LK F+A     L+Y  SEGGENLSVGQ+QLVCLARALL+K+++L+LDEATAA+DLETDDLIQ +IR QF+ CTVLTIAHRLNTIMDY RV+VL++GR+ E D+P NL+A  K IF+ MA DAGLA
Sbjct:  955 ETGRVKMTVFWQYMKAVGLAISVFICFLYSCQNAAAIGANVWLSDWTNEPVINQTQQ--NTQMRVGVYAALGILQGLLVMTSSFSLAIAGIGAARKLHSALLDNKMHTPQSFYDTTPIGRIINRFSKDIYVIDEVIPGTILMFLATFFTSLSTMIVIVASTPLFAVVIIPLAIAYIFVQRFYVATSRQLKRLESVSRSPIYSHFSETITGASIIRAYGRQNSFIVLSDNKVDENQKSYYPGIVSNRWLGVRVEFVGNCVVLFAALFAVLGREHLSPGLVGLSVSYALQVTMSLNWMVRMTSDLETNIVAVERVKEYAENETEAPWHIEDTKPPEDWPSKGEVELSNYSVRYRAGLDLVLKNLNLKVNGGEKVGIVGRTGAGKSSMTLCLFRILEPAEGIVKIDNVNISEIGLQDLRSRLTIIPQDPVLFSGTLRMNLDPFNKYSDDEIWKALELSNLKKFVAGQPSQLEYECSEGGENLSVGQRQLVCLARALLRKTRILILDEATAAIDLETDDLIQMTIRTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGRIAEFDTPTNLIA-LKGIFYGMAKDAGLA 1532

HSP 3 Score: 88.1965 bits (217), Expect = 1.021e-16
Identity = 72/275 (26.18%), Postives = 129/275 (46.91%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            LN + ++ S+L   +V+++RI+ +    +    ++         P +  +   N +  +      +L+N+N++V +G  + +VG+ G GKSSL  AL   +E  EG +              +R  +  +PQ   + + T++ N+      ++     VLE   L + +     G Q  + E G NLS GQKQ V LARA+   + V +LD+  +AVD      I  ++       +  T + + H ++ +   D ++VL  GRV E+ S Q LL
Sbjct:  591 LNMLPQVISNLAQASVSIKRIQNFL---ANDELDLNAVTKDKTLPGNA-ITVHNGTFSWAKNGGAILQNINLLVPSGSLVAVVGQVGCGKSSLVSALLGEMEKEEGEV-------------SVRGSVAYVPQQAWIQNCTLKDNILFGRAANEKNYKKVLEACALVTDLEVLPGGDQTEIGEKGINLSGGQKQRVSLARAVFSNADVYLLDDPLSAVDAHVAKHIFDNVIGPDGLLRGKTRVLVTHGISFLPQVDHIVVLVDGRVTEMGSYQELL 848

HSP 4 Score: 67.3958 bits (163), Expect = 2.514e-10
Identity = 66/270 (24.44%), Postives = 120/270 (44.44%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVE-VSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGD----QTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            V+++R+ ++   +     ++E   PP++ P    V++ + +  +      VL N+N++V  G  V +VG  G+GK+S+   L   L    G V               R  +  IPQ     + +L+ N+    P   +  + + +A  L+ +LK   AG     + E  E G NLS GQ+Q + LARA+ +   + +LD+  +A+D      I   +          T + + H L  +    ++ V+  G ++E  T T L+   G F
Sbjct: 1260 VAVERVKEYAENETEAPWHIEDTKPPEDWPSKGEVELSNYSVRYRAGLDLVLKNLNLKVNGGEKVGIVGRTGAGKSSMTLCLFRILEPAEGIVKIDNVNISEIGLQDLRSRLTIIPQDPVLFSGTLRMNL---DPFNKYSDDEIWKALELS-NLKKFVAGQPSQLEYECSEGGENLSVGQRQLVCLARALLRKTRILILDEATAAIDLETDDLIQMTI---RTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGRIAEFDTPTNLIALKGIF 1522
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Xenopus
Match: ABCC1 (ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51])

HSP 1 Score: 743.806 bits (1919), Expect = 0.000e+0
Identity = 400/903 (44.30%), Postives = 575/903 (63.68%), Query Frame = 2 
Query:   47 SLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHL-LNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKL----EKQNGFTSNYKPLKSEE---EETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENV--EVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            S CS   ++   W   + W T++PD T CFQ T+L WIP ++LW     Y   L  K    Y      N  K T I FIL+     +   +  E   ++Y  P   + P +  I+ +L  +L +    KG+ SSGV+  +W++ LL +I +  S+       D   D++     +F     + SF       L +F  SE++N+               P+         PCPE+  SFLS++TF W++ ++++G+++PL  KDL++L + D    +V  +   W +E  + K  K   K+    +KQ       K L S+E   EE E   V+            PS L+AL+ T G  + ++  FK  +D+L F+ PQ+L L I F+ + +   WHG+L    LF  + ++++I  +Y+H C+VTGMR +TAV+G++YRKAL +++++R+ +T+GEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A Y LWQ LGPSVLAG+A+M+ L+P+N +I  K KK Q  QMK KDNRIKLMNEIL+GIK+LKLYAWE +F++ +  IR DE ++L+ + YL AV   TW CAPFLVAL TF  + L    +VL A KAFVSL+LFNIL FP++MLP VI   +QA VSLKR+  FL  +EL+ E++  E     E  + + D TFSW + + P L +IN+ +PEGSLVAVVG VG GK+SL+SAL+GE+ K  G V  +GS+GY+ QQAW +NASL+DN+LF +      Y +VIEACAL  DL++LP GD+TEIGEKG+NLSGGQKQR+SLARAVY +  +YLLDDPLSAVD+HVGKHIFD+VIGP G+L +KTRILVTHG++YLP++D I VM DG ++E G++ +LL  +G+FAEF+RTY
Sbjct:    3 SFCSYDGSE-RFWDSNLTWYTENPDFTKCFQNTVLIWIPCIYLWFCLPFYFAYL-RKNDQGYIQMSHLNKAK-TAIGFILWLACWADLFYSFWERSQSIYRAPVYVVSPTVLGITMLLATFLIQYERIKGVQSSGVMLNFWIVALLCAIIIFRSKVLHALKPDAQIDIYSKHYPSFHG---WFSFGKLHRPPLPLF--SERVND---------------PN---------PCPESSASFLSQITFWWISRMMVQGFKRPLEAKDLWSLNKEDKSLEVVPVLSKNWEKEYNKAKAKKVPLKMVYSPKKQT------KKLNSKEDVREEAEALIVKPAPKEL-----EPSLLKALYKTFGPYFFISCFFKFFHDVLMFSGPQLLQLLIKFVGDKDAPDWHGYLYTFLLFFCACLQTLILHKYFHICFVTGMRLKTAVVGLVYRKALVINNSARRTSTIGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILAFYLLWQNLGPSVLAGIAVMVLLVPVNAVIAMKTKKYQVVQMKCKDNRIKLMNEILNGIKVLKLYAWELAFKEKVLGIRKDELKVLKKSAYLAAVGTFTWVCAPFLVALSTFAVYVLIDKQNVLDAEKAFVSLALFNILRFPLNMLPMVISSMVQASVSLKRLRVFLSHEELEPESIIREPQKSSEGSINMKDATFSWSRNDLPSLKDINISIPEGSLVAVVGQVGCGKSSLLSALLGEMEKQDGYVAMKGSVGYVSQQAWIQNASLKDNVLFGRESNESMYKKVIEACALLPDLEILPTGDRTEIGEKGVNLSGGQKQRVSLARAVYCNTDIYLLDDPLSAVDAHVGKHIFDKVIGPKGMLKNKTRILVTHGVSYLPQMDSIIVMVDGKITEVGSYQDLLMQDGAFAEFLRTY 862

HSP 2 Score: 617.076 bits (1590), Expect = 0.000e+0
Identity = 299/584 (51.20%), Postives = 427/584 (73.12%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMC---CSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A+ G VK +VF  Y+++      F  +F   L+MC    S+ +N +LS WT+    NGTQ   +    L +YG+LG  Q + +   + A++ G  LAS+ LH  LL N+LR P SFF+ TP G ++NR  K+IDT+D +IP  I++++ +   VIG+  +I  ++P   + + PL  +Y+  QRFY+ TSRQLKR++S+ RSP+YSHF E+++G+S IRA+     FI+  D   DENQ A+YP+IVS RWL   LE +GN ++L + + AV++R+T+  G  GLS+SYALQ+T  LN++VRM+S+LE++ VAVER+KEYA+++ EA W ++E+   + WP  G++EF  Y +RYR  LDL L+N+N+ +  GEK+GIVGRTGAGKSSL L LFR+ E A G I+ID  ++ K+GLHDLR ++TIIPQDP+LFSGT+RMNLDPF++++D ++W+ LE+++LK F+A   + L +  +EGGENLS+GQ+QLVCLARALL+K+K+LVLDEATAAVDLETD LIQS+IR++F+ CTV+TIAHRLNTIMDY +V+VL++G+V E DSP NLL  ++ IF +MA D+GL
Sbjct:  932 AKTGRVKLAVFWEYMKAIGLFLCFLSIF---LFMCNHVASLASNYWLSLWTDDKVVNGTQQNTT--MRLSVYGALGFSQGIAVYGYSTAVSLGGILASRFLHTDLLHNVLRFPMSFFERTPSGNLVNRFSKEIDTIDNTIPQIIKMFMGSLFNVIGACVIILTATPIVAVIIPPLGLVYFFVQRFYVATSRQLKRLESVSRSPVYSHFNETLLGSSVIRAFGEQKRFIQISDFKVDENQRAYYPSIVSNRWLAIRLEFVGNCIVLFASLFAVISRTTLSPGLVGLSVSYALQVTTYLNWLVRMSSELETNIVAVERVKEYADLKQEAAWTVQETAPEATWPHEGKIEFRGYGLRYREDLDLALKNINVTIQGGEKVGIVGRTGAGKSSLTLGLFRINEAAAGEIVIDGCNLAKIGLHDLRFRVTIIPQDPVLFSGTLRMNLDPFDKYTDDDIWTSLELAHLKRFVANLPDRLNHECAEGGENLSIGQRQLVCLARALLRKTKILVLDEATAAVDLETDGLIQSTIRKEFQDCTVITIAHRLNTIMDYTKVIVLDKGQVVEFDSPSNLL-QQQGIFFNMAKDSGL 1509

HSP 3 Score: 78.9518 bits (193), Expect = 7.999e-14
Identity = 68/280 (24.29%), Postives = 133/280 (47.50%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNI-EESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWS-VLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            LN +  + S +   +V+++R++ +   E   P +I  E Q  S+   + +    ++S    P L    +++NI +  G  + +VG+ G GKSSL  AL   +E  +G +              ++  +  + Q   + + +++ N+  F + S+  ++  V+E   L   +     G +  + E G NLS GQKQ V LARA+   + + +LD+  +AVD      I   +   +   K  T + + H ++ +   D ++V+  G++ E+ S Q+LL  +
Sbjct:  591 LNMLPMVISSMVQASVSLKRLRVFLSHEELEPESIIREPQKSSEGSINMKDATFSWSRNDLPSL----KDINISIPEGSLVAVVGQVGCGKSSLLSALLGEMEKQDGYVA-------------MKGSVGYVSQQAWIQNASLKDNV-LFGRESNESMYKKVIEACALLPDLEILPTGDRTEIGEKGVNLSGGQKQRVSLARAVYCNTDIYLLDDPLSAVDAHVGKHIFDKVIGPKGMLKNKTRILVTHGVSYLPQMDSIIVMVDGKITEVGSYQDLLMQD 852

HSP 4 Score: 65.855 bits (159), Expect = 6.391e-10
Identity = 68/278 (24.46%), Postives = 111/278 (39.93%), Query Frame = 2 
Query: 1928 VIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGS-------------IGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTR--------ILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            V V  ++ Y  LK+   + V +       E + P E  ++       + +     L NIN+ +  G  V +VG  G+GK+SL   L       +G ++  G              +  IPQ     + +L+ N+       +      +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD           +   GL+ S  R        I + H L  +    K+ V+  G V E  + + LL+  G F
Sbjct: 1238 VAVERVKEYADLKQEAAWTVQETAP----EATWPHEGKIEFRGYGLRYREDLDLALKNINVTIQGGEKVGIVGRTGAGKSSLTLGLFRINEAAAGEIVIDGCNLAKIGLHDLRFRVTIIPQDPVLFSGTLRMNLDPFDKYTDDDIWTSLELAHLKRFVANLPDRLNHECAEGGENLSIGQRQLVCLARALLRKTKILVLDEATAAVD-----------LETDGLIQSTIRKEFQDCTVITIAHRLNTIMDYTKVIVLDKGQVVEFDSPSNLLQQQGIF 1500
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Mouse
Match: Abcc1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 1 [Source:MGI Symbol;Acc:MGI:102676])

HSP 1 Score: 760.37 bits (1962), Expect = 0.000e+0
Identity = 392/902 (43.46%), Postives = 567/902 (62.86%), Query Frame = 2 
Query:   47 SLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFR------KKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVE---VSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            S CS   +D  LW   + W+T +PD T CFQ T+L W+P  +LW SC        ++    Y      N  K+ L  F+      +   +  E    +   P L + P L  I+ +L  +L +L  +KG+ SSG++  +WL+ LL ++ ++ S+       D   D+FR  T    F LV V  +L+CF+D +                   PL S    D      R PCPE+  SFLS++TF W+TG+++ GYRQPL   DL++L + DT + +V  +   W +E  + ++   R      K   K  G +     L   EE      V+        K + PS  + L+ T G  ++++ ++K  +DL+ FA P+IL L I F+++     W G+     LF+ + ++++   QY+H C+V+GMR +TAV+G +YRKAL +++ +RK +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+YFLW  LGPSVLAGVA+MI ++P+N ++  K K  Q   MK KDNRIKLMNEIL+GIK+LKLYAWE +F+  + +IR +E ++L+ + YL AV   TW C PFLVAL TF  F      ++L A KAFVSL+LFNIL FP+++LP VI   +QA VSLKR+  FL  +EL+ +++E   +   +   + + + TF+W + E P L  I   +PEG+LVAVVG VG GK+SL+SAL+ E+ KV G V  +GS+ Y+PQQAW +N SL++NILF  PL  + Y  V+EACAL  DL++LP+GD+TEIGEKG+NLSGGQKQR+SLARAVY +  +YL DDPLSAVD+HVGKHIF++V+GP GLL +KTRILVTHG++YLP+VD I VM  G +SE G++ ELL  +G+FAEF+RTY
Sbjct:    5 SFCSADGSD-PLWDWNVTWHTSNPDFTKCFQNTVLTWVPCFYLW-SCFPLYFFYLSRHDRGYIQMTHLNKTKTALGFFLWIICWADLFYSFWERSQGVLRAPVLLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIISALKKDAHVDVFRDSTFYLYFTLVLVQLVLSCFSDCS-------------------PLFSETVHD------RNPCPESSASFLSRITFWWITGMMVHGYRQPLESSDLWSLNKEDTSEEVVPVLVNNWKKECDKSRKQPVRIVYAPPKDPSKPKGSSQ----LDVNEE------VEALIVKSPHKDREPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPKILELIINFVNDREAPDWQGYFYTALLFVSACLQTLALHQYFHICFVSGMRIKTAVVGAVYRKALLITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYFLWLSLGPSVLAGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMSIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDERNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRSIKSGEGNSITVKNATFTWARGEPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGHPLQENYYKAVMEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNSDIYLFDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFLRTY 869

HSP 2 Score: 626.706 bits (1615), Expect = 0.000e+0
Identity = 306/582 (52.58%), Postives = 433/582 (74.40%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGST-NGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A+ G V+ SV+ +Y+++     +F  +F +      ++ +N +LS WT+     NGTQ   ++ F L +YG+LG  Q   I   + A++ G   AS+ LH  LL N+LR+P SFF+ TP G ++NR  K++DTVD  IP  I++++ +   VIG++ +I +++P   + + PL  +Y+  QRFY+ +SRQLKR++S+ RSP+YSHF E+++G S IRA++  + FI + D+  DENQ A+YP+IV+ RWL   LE +GN ++L + + AV++R ++ +G  GLS+SY+LQIT  LN++VRM+S++E++ VAVER+KEY+E E EAPW I+E+   S WP SGRVEF +Y +RYR  LDLVL+++N+ ++ GEK+GIVGRTGAGKSSL L LFR+ E AEG IIID  +I K+GLH+LR KITIIPQDP+LFSG++RMNLDPF+Q+SD E+W  LE+++LK F++   + L +  +EGGENLSVGQ+QLVCLARALL+K+K+LVLDEATAAVDLETD+LIQS+IR QF+ CTVLTIAHRLNTIMDY RV+VL++G V+E  +P  LL  ++ IF+SMA DAGL
Sbjct:  949 AQTGQVQLSVYWNYMKAIGLFITFLSIFLFLCNHVSALASNYWLSLWTDDPPVVNGTQA--NRNFRLSVYGALGILQGAAIFGYSMAVSIGGIFASRRLHLDLLYNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSELL-QQRGIFYSMAKDAGL 1527

HSP 3 Score: 78.5666 bits (192), Expect = 6.783e-14
Identity = 68/275 (24.73%), Postives = 123/275 (44.73%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            LN +  + S +   +V+++R++ +   E   P +IE     S   +S  V+  N +  +  G    L  +   +  G  + +VG+ G GKSSL  AL   ++  EG +              L+  +  +PQ   + + ++R N+   +   +    +V+E   L   +     G +  + E G NLS GQKQ V LARA+   S + + D+  +AVD      I   +       K  T + + H ++ +   D ++V+  G++ E+ S Q LL
Sbjct:  597 LNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRSIKSGEGNSITVK--NATFTWARGEPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVT-------------LKGSVAYVPQQAWIQNDSLRENILFGHPLQENYYKAVMEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNSDIYLFDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELL 856

HSP 4 Score: 77.411 bits (189), Expect = 1.805e-13
Identity = 108/477 (22.64%), Postives = 193/477 (40.46%), Query Frame = 2 
Query: 1370 KETTVGEIVN-----LMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKL---QAKQMKMKDNRIK-----LMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPF-LVALCT--FTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGD-ELDTENVEVSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-------------SIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            + T  G +VN     L +VDS   Q +  F+  L++    ++I            +L    +   +IP  G++   V++     ++Q+K  ++  +       NE L G+ +++ +  +  F     +++ DE        Y  ++ A  W       V  C   F A     S H L+A    +S+S    ++  ++ L  +        V+++R+ ++   + E   +  E +PP   P    V+  D    + +    VL +IN+ +  G  V +VG  G+GK+SL   L        G ++  G              I  IPQ     + SL+ N+       + +    +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G V E G  +ELL+  G F
Sbjct: 1062 ERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVII------------ILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQ-SDLKVDE----NQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTI---RTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSELLQQRGIF 1518
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Mouse
Match: Abcc3 (ATP-binding cassette, sub-family C (CFTR/MRP), member 3 [Source:MGI Symbol;Acc:MGI:1923658])

HSP 1 Score: 729.939 bits (1883), Expect = 0.000e+0
Identity = 388/898 (43.21%), Postives = 550/898 (61.25%), Query Frame = 2 
Query:   50 LCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTK---FRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVE---VSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            LC         W   +   T  PD+T CFQ ++L W+P ++LW +   Y+  L       Y      +  K+ L   +     ++   +    I    P P  ++ P++  I+ +L   L +    +G+ SSGVL  +WLL ++ +I    S+        +  D FR  T    F LVF + IL+CF                    E  PL S  P++    ++  PCPE    F S+L+F W T L I GYR+PL  +DL++L E D    +V  +   W ++  +  +++      K+  ++      +P KS++                     PSFLRAL  T     +++  F +  +LL F  PQ+L + I FI +P    W GFLLA  +FL S ++++I  QYYH  +V  +R RTA+IG+IYRKAL ++++ ++E+TVGE+VNLMSVD+Q+  DV  F+++LW+AP+ +++AIYFLWQ LGPS LAGVA+++ LIP+NG +  K+K  Q KQMK KD+RIKLM+EIL+GIK+LKLYAWE SF + ++ IR  E ++LR   YL A+S   W C PFLV L T   +     S+VL A KAFVSLSLFNIL  P++MLP +I    QA VSLKRI  FL  +ELD + VE   +SP     + I +GTF+W +   P L ++N+++P+G+LVAVVG VG GK+SL+SAL+GE+ K+ G V  +GS+ Y+PQQAW +N +LQ+N+LF +P+   +Y + +E CAL  DL VLP GDQTEIGEKGINLSGGQ+QR+SLARAVY D +++LLDDPLSAVDSHV KHIFDQVIGP G+L+ KTR+LVTHG+++LP+ D I V+  G VSE G ++ LL+++GSFA F+R Y
Sbjct:    4 LCGSGELGSKFWDSNLSIYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFYL-RHHQLGYIVLSWLSRLKTALGVLLWCVSWVDLFYSFHGLIHGSSPAPVFFVTPLVVGITMLLATLLIQYERLRGVQSSGVLIIFWLLCVICAIIPFRSKILSALAEGKILDPFRFTTFYIYFALVFCALILSCF-------------------KEKPPLFS--PEN----LDTNPCPEASAGFFSRLSFWWFTRLAILGYRRPLEDRDLWSLSEEDCSHKVVQRLLEAWQKQQNQASRSQTATAEPKIPGEDAVLLKPRP-KSKQ---------------------PSFLRALVRTFTSSLLMSACFNLIQNLLGFVNPQLLSILIRFISDPTAPTWWGFLLAGLMFLSSTMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAISTFIWICTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQNELDPQCVERKTISP--GYAITIHNGTFTWAQDLPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGSFANFLRNY 851

HSP 2 Score: 636.336 bits (1640), Expect = 0.000e+0
Identity = 313/583 (53.69%), Postives = 417/583 (71.53%), Query Frame = 2 
Query: 2999 VAEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            +AE G VK SV+  Y +S     + ++   Y      ++GAN++LS W+     +G QN  S    LG+Y +LG  Q L +++  F +  G   A++ LH  LL N +R+P SFFDTTP GRILNR  KDI  +D  +  TI + L +    I +I VI  S+P F++ ++PL  +Y   QRFY+ TSRQLKR++SI RSPI+SHF E++ G S IRAY    DF    D   D NQ + YP I S RWL  ++E +GN V+L + + AV+ R+++  G  GLS+SYALQ+T  LN+M+RM SDLES+ +AVER+KEY++ ++EAPW +E ++A   WP  G VEF NYSVRYRPGL+LVL+N+ + V  GEK+GIVGRTGAGKSS+ L LFR++E AEG I+ID  ++  +GLHDLRS++TIIPQDPILFSGT+RMNLDPF ++S+ ++W  LE+S+L +F++    GL +  +EGG+NLSVGQ+QLVCLARALL+KS+VLVLDEATAA+DLETDDLIQ +IR QF+ CTVLTIAHRLNTIMDY+RV+VL++G V E DSP NL+A    IF+ MA DAGLA
Sbjct:  944 IAETGNVKLSVYWDYAKSMGLCTTLSICLLYGGQSAAAIGANVWLSAWSNDAEEHGQQNKTS--VRLGVYAALGILQGLLVMLSAFTMVVGAIQAARLLHEALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLLNSFFTSISTIMVIVASTPLFMVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGRIQDFKVLSDTKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGRNSLNPGLVGLSVSYALQVTMALNWMIRMISDLESNIIAVERVKEYSKTKTEAPWVVESNRAPEGWPTRGMVEFRNYSVRYRPGLELVLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIA-AGGIFYGMAKDAGLA 1523

HSP 3 Score: 79.337 bits (194), Expect = 3.915e-14
Identity = 102/415 (24.58%), Postives = 179/415 (43.13%), Query Frame = 2 
Query: 3506 LVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCD-IMTDENQM----AWYPNIVSYRWLQFYLETIGNLVILLS-GVLAVVTRSTI---GSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWS-VLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKS 4711
            L+PL     M  +   Y  +Q+K  DS  R  + S   E + G   ++ Y     F+++   I   E Q+    A+   I ++ W+         LV L++ GV   V  S +      +  LS+   L+I   LN + ++ S L   +V+++RI+++       P  +E       +     +   N +  +   L   L +LNI +  G  + +VG  G GKSSL  AL   +E  EG +              ++  +  +PQ   + + T++ N+  F Q  + + +   LE   L + +     G Q  + E G NLS GQ+Q V LARA+   + + +LD+  +AVD      I   +          T + + H ++ +   D ++VL  G+V E+     LL ++ S
Sbjct:  461 LIPLNGAVSMKMK--TYQVKQMKFKDS--RIKLMS---EILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAISTFIWI-----CTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIP--LNMLPQLISGLTQASVSLKRIQDFLNQNELDPQCVERKTISPGYA----ITIHNGTFTWAQDLPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVV-------------SVKGSVAYVPQQAWIQNCTLQENV-LFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGS 843

HSP 4 Score: 67.0106 bits (162), Expect = 2.598e-10
Identity = 59/216 (27.31%), Postives = 97/216 (44.91%), Query Frame = 2 
Query: 2090 VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-SIGYIPQQAWCRNASL--QDNILFSKPLINH-----KYN-----RVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            VL N+ + V  G  V +VG  G+GK+S+   L   L    G ++  G ++ +I         ++  QD ILFS  L  +     +Y+     R +E   L   +   PAG   +  E G NLS GQ+Q + LARA+ +   V +LD+  +A+D      I   +          T + + H L  +   +++ V+  G V+E  +   L+   G F
Sbjct: 1301 VLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTI---RTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIAAGGIF 1513
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Mouse
Match: Abcc3 (ATP-binding cassette, sub-family C (CFTR/MRP), member 3 [Source:MGI Symbol;Acc:MGI:1923658])

HSP 1 Score: 729.554 bits (1882), Expect = 0.000e+0
Identity = 388/898 (43.21%), Postives = 550/898 (61.25%), Query Frame = 2 
Query:   50 LCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTK---FRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVE---VSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            LC         W   +   T  PD+T CFQ ++L W+P ++LW +   Y+  L       Y      +  K+ L   +     ++   +    I    P P  ++ P++  I+ +L   L +    +G+ SSGVL  +WLL ++ +I    S+        +  D FR  T    F LVF + IL+CF                    E  PL S  P++    ++  PCPE    F S+L+F W T L I GYR+PL  +DL++L E D    +V  +   W ++  +  +++      K+  ++      +P KS++                     PSFLRAL  T     +++  F +  +LL F  PQ+L + I FI +P    W GFLLA  +FL S ++++I  QYYH  +V  +R RTA+IG+IYRKAL ++++ ++E+TVGE+VNLMSVD+Q+  DV  F+++LW+AP+ +++AIYFLWQ LGPS LAGVA+++ LIP+NG +  K+K  Q KQMK KD+RIKLM+EIL+GIK+LKLYAWE SF + ++ IR  E ++LR   YL A+S   W C PFLV L T   +     S+VL A KAFVSLSLFNIL  P++MLP +I    QA VSLKRI  FL  +ELD + VE   +SP     + I +GTF+W +   P L ++N+++P+G+LVAVVG VG GK+SL+SAL+GE+ K+ G V  +GS+ Y+PQQAW +N +LQ+N+LF +P+   +Y + +E CAL  DL VLP GDQTEIGEKGINLSGGQ+QR+SLARAVY D +++LLDDPLSAVDSHV KHIFDQVIGP G+L+ KTR+LVTHG+++LP+ D I V+  G VSE G ++ LL+++GSFA F+R Y
Sbjct:    4 LCGSGELGSKFWDSNLSIYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFYL-RHHQLGYIVLSWLSRLKTALGVLLWCVSWVDLFYSFHGLIHGSSPAPVFFVTPLVVGITMLLATLLIQYERLRGVQSSGVLIIFWLLCVICAIIPFRSKILSALAEGKILDPFRFTTFYIYFALVFCALILSCF-------------------KEKPPLFS--PEN----LDTNPCPEASAGFFSRLSFWWFTRLAILGYRRPLEDRDLWSLSEEDCSHKVVQRLLEAWQKQQNQASRSQTATAEPKIPGEDAVLLKPRP-KSKQ---------------------PSFLRALVRTFTSSLLMSACFNLIQNLLGFVNPQLLSILIRFISDPTAPTWWGFLLAGLMFLSSTMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAISTFIWICTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQNELDPQCVERKTISP--GYAITIHNGTFTWAQDLPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGSFANFLRNY 851

HSP 2 Score: 636.336 bits (1640), Expect = 0.000e+0
Identity = 313/583 (53.69%), Postives = 417/583 (71.53%), Query Frame = 2 
Query: 2999 VAEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            +AE G VK SV+  Y +S     + ++   Y      ++GAN++LS W+     +G QN  S    LG+Y +LG  Q L +++  F +  G   A++ LH  LL N +R+P SFFDTTP GRILNR  KDI  +D  +  TI + L +    I +I VI  S+P F++ ++PL  +Y   QRFY+ TSRQLKR++SI RSPI+SHF E++ G S IRAY    DF    D   D NQ + YP I S RWL  ++E +GN V+L + + AV+ R+++  G  GLS+SYALQ+T  LN+M+RM SDLES+ +AVER+KEY++ ++EAPW +E ++A   WP  G VEF NYSVRYRPGL+LVL+N+ + V  GEK+GIVGRTGAGKSS+ L LFR++E AEG I+ID  ++  +GLHDLRS++TIIPQDPILFSGT+RMNLDPF ++S+ ++W  LE+S+L +F++    GL +  +EGG+NLSVGQ+QLVCLARALL+KS+VLVLDEATAA+DLETDDLIQ +IR QF+ CTVLTIAHRLNTIMDY+RV+VL++G V E DSP NL+A    IF+ MA DAGLA
Sbjct:  943 IAETGNVKLSVYWDYAKSMGLCTTLSICLLYGGQSAAAIGANVWLSAWSNDAEEHGQQNKTS--VRLGVYAALGILQGLLVMLSAFTMVVGAIQAARLLHEALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLLNSFFTSISTIMVIVASTPLFMVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGRIQDFKVLSDTKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGRNSLNPGLVGLSVSYALQVTMALNWMIRMISDLESNIIAVERVKEYSKTKTEAPWVVESNRAPEGWPTRGMVEFRNYSVRYRPGLELVLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIA-AGGIFYGMAKDAGLA 1522

HSP 3 Score: 79.337 bits (194), Expect = 3.753e-14
Identity = 102/417 (24.46%), Postives = 177/417 (42.45%), Query Frame = 2 
Query: 3506 LVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCD-IMTDENQM----AWYPNIVSYRWLQFYLETIGNLVILLS-GVLAVVTRSTI---GSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNL---DPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKS 4711
            L+PL     M  +   Y  +Q+K  DS  R  + S   E + G   ++ Y     F+++   I   E Q+    A+   I ++ W+         LV L++ GV   V  S +      +  LS+   L+I   LN + ++ S L   +V+++RI+++       P  +E       +     +   N +  +   L   L +LNI +  G  + +VG  G GKSSL  AL   +E  EG +              ++  +  +PQ   + + T++ N+    P N     +    LE   L + +     G Q  + E G NLS GQ+Q V LARA+   + + +LD+  +AVD      I   +          T + + H ++ +   D ++VL  G+V E+     LL ++ S
Sbjct:  461 LIPLNGAVSMKMK--TYQVKQMKFKDS--RIKLMS---EILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAISTFIWI-----CTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIP--LNMLPQLISGLTQASVSLKRIQDFLNQNELDPQCVERKTISPGYA----ITIHNGTFTWAQDLPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVV-------------SVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQ---ALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGS 843

HSP 4 Score: 67.0106 bits (162), Expect = 2.597e-10
Identity = 59/216 (27.31%), Postives = 97/216 (44.91%), Query Frame = 2 
Query: 2090 VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-SIGYIPQQAWCRNASL--QDNILFSKPLINH-----KYN-----RVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            VL N+ + V  G  V +VG  G+GK+S+   L   L    G ++  G ++ +I         ++  QD ILFS  L  +     +Y+     R +E   L   +   PAG   +  E G NLS GQ+Q + LARA+ +   V +LD+  +A+D      I   +          T + + H L  +   +++ V+  G V+E  +   L+   G F
Sbjct: 1300 VLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTI---RTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIAAGGIF 1512
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Mouse
Match: Abcc2 (ATP-binding cassette, sub-family C (CFTR/MRP), member 2 [Source:MGI Symbol;Acc:MGI:1352447])

HSP 1 Score: 639.802 bits (1649), Expect = 0.000e+0
Identity = 346/875 (39.54%), Postives = 530/875 (60.57%), Query Frame = 2 
Query:  134 FQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGK------FNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRK-KLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSF-----LRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYL 2722
            F+ T+L WIPL FLW+      P  W +   IYR+R K      F + K   +  +L    ++    ++E       PP  Y  PIL   + +L++ +          +S  L  +W+L LL  I    +  R L   D     T +  F     FVS+       +        ++ F +  D T                    P    SFLS +TF+W    V+KGY+ PLT +D++ + EN    ++ +  +    ++ Q+ +Q   R+ K  +Q+   +++   K + +  ++  ++++   K++ + +  F     ++ALF T     + + + K+A+D+L F  PQ+L   I F+ +P+ Y W G++ AI +F +++I+S   Q Y+  C+V GM  RT +I  +Y+KAL LS+ +R++ T+GE VNLMSVDSQKL DV +++H+LW++ + I ++I+FLW+ELGPS+LAGV LM+ L+P+NG++ +K++K+Q + MK KD R+K+MNEILSGIKILK +AWE SF++ + +IR  E R L   + L  +        P LV++ TF+ + L  S +VL A KAF S++LFNIL FP++MLP VI   IQA VS+ R+ ++L  D+LD   +      +K V+  + +F+W +     + ++N+++  G LVAVVGTVGSGK+SLISA++GE+  V G +  +GSI Y+PQQAW +N +++DNILF       KY RVIEACAL  DL++LP GD  EIGEKGINLSGGQK R+SLARA YQD  +Y+LDDPLSAVD+HVGKHIF++V+GP+GLLS KTRILVTHG+ +LP+VD+I V+  G + E G++++L+   G FA+  +T++
Sbjct:   26 FEQTVLVWIPLGFLWL----LAP--W-QLYRIYRSRTKRFAITKFYLAKQVFVVCLLILAAIDLSLALTEDTGQATIPPVKYTNPILYLCTWLLVLVIQHCRQCCIQKNSWFLSMFWILSLLCGIFQFQTLIRAL-LQDSKSNMTYSCLF-----FVSYGFQIVILI--------LSAFSESSDSTH------------------APSATASFLSSVTFSWYDSTVLKGYKHPLTIEDVWDIEENLKAKSLTSKFKTIMTKDLQKARQALQRRLKKSQQSPEGTSHGLTKKQSQSQDVLVLEDSKKKKKKSEATKDFPKSWLVKALFKTFYVVILKSFILKLAHDILLFLNPQLLKFLIGFVKDPDSYPWVGYIYAILMFSVTLIQSFFLQCYFQFCFVLGMTVRTTIIASVYKKALTLSNLARRQYTIGETVNLMSVDSQKLMDVTNYIHLLWSSVLQIALSIFFLWRELGPSILAGVGLMVLLVPVNGVLATKIRKIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKEQVNSIRKKELRNLLRFSQLQTILIFILHLTPTLVSVITFSVYVLVDSQNVLNAEKAFTSITLFNILRFPLAMLPMVISSVIQASVSVDRLEQYLGSDDLDLSAIRHVCHFDKAVQFSEASFTWDRDLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLISAMLGEMENVHGHITIKGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVVGPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLMDKKGVFAKNWKTFM 861

HSP 2 Score: 555.058 bits (1429), Expect = 9.387e-170
Identity = 289/582 (49.66%), Postives = 410/582 (70.45%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWT-ETGSTNGTQN-PDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            E G VKFS++L Y+++  +     +V  Y L     +G N++LS WT ++   NGT N P  +   +G++G+LG  Q +F+L  +    Y    ASK+LH  LL NILRAP SFFDTTP GRI+NR   DI TVD ++P T+R WL+   G++ ++ +I +++P F++ ++PL+ +Y   Q FY+ TSRQL+R+DS+ +SPIYSHF E++ G   IRA++    F+   +   D NQ   +  I S RWL   LE +GNL++  S +L V+ ++++     G  +S AL IT  LN++VRMTS++E++ VAVERI EY  +++EAPW + + +  +DWP  G ++F NY VRYRP LDLVL+ +   + + EK+G+VGRTGAGKSSL   LFR++E A G IIID  DI  +GLHDLR ++TIIPQDPILFSG +RMNLDPFN++SD E+W  LE+++LKSF+A    GL + V+EGG+NLS+GQ+QL+CL RA+L+KSK+LVLDEATAAVDLETD LIQ++IR +F +CTV+TIAHRL+TIMD D++MVL+ G++ E  SP+ LL+N    F+ MA +AG+
Sbjct:  956 ETGKVKFSIYLKYLQAVGWWSLLFIVIFYVLNYVAFIGTNLWLSAWTSDSEKQNGTDNSPSQRDMRIGVFGALGIAQGIFLLSSSLWSIYACRNASKTLHRQLLTNILRAPMSFFDTTPTGRIVNRFAGDISTVDDTLPQTLRSWLLCFFGIVSTLVMICMATPIFIIIIIPLSILYVSVQVFYVATSRQLRRLDSVTKSPIYSHFSETVSGLPVIRAFEHQQRFLANSEKQIDTNQKCVFSWITSNRWLAIRLELVGNLIVFCSALLLVIYKNSLTGDTVGFVLSNALNITQTLNWLVRMTSEVETNIVAVERINEYINVDNEAPW-VTDKKPPADWPKKGEIQFNNYQVRYRPELDLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDIASIGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALELAHLKSFVAGLQLGLLHEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNEFSQCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLSNMGP-FYLMAKEAGI 1535

HSP 3 Score: 77.0258 bits (188), Expect = 1.920e-13
Identity = 60/233 (25.75%), Postives = 111/233 (47.64%), Query Frame = 2 
Query: 4028 VEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIF 4717
            V+F   S  +   L+  ++++N+ +  G+ + +VG  G+GKSSL  A+   +E   G I I             +  I  +PQ   + +GTI+ N+   +++ + +   V+E   L   +     G    + E G NLS GQK  V LARA  + + + +LD+  +AVD      I + +          T + + H ++ +   D ++VL +G + E  S  +L+ ++K +F
Sbjct:  635 VQFSEASFTWDRDLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLISAMLGEMENVHGHITI-------------KGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVVGPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLM-DKKGVF 853

HSP 4 Score: 76.6406 bits (187), Expect = 2.646e-13
Identity = 74/268 (27.61%), Postives = 111/268 (41.42%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAP-------VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVS-------------GRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            V+++RIN+++  D       +  PP + P K   G   +   +         VL  I   +     V VVG  G+GK+SL + L   L                 G    RG +  IPQ     + +L+ N+       + +  R +E   L   +  L  G   E+ E G NLS GQ+Q + L RAV +   + +LD+  +AVD      I   +       S  T I + H L  +   DKI V+  G + E G+  ELL N G F
Sbjct: 1265 VAVERINEYINVDNEAPWVTDKKPPADWPKK---GEIQFNNYQVRYRPELDLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDIASIGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALELAHLKSFVAGLQLGLLHEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNE---FSQCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLSNMGPF 1526
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Mouse
Match: Abcc6 (ATP-binding cassette, sub-family C (CFTR/MRP), member 6 [Source:MGI Symbol;Acc:MGI:1351634])

HSP 1 Score: 506.138 bits (1302), Expect = 1.962e-152
Identity = 314/889 (35.32%), Postives = 492/889 (55.34%), Query Frame = 2 
Query:  101 WNT--QDPD----ITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKF----NIFKSTLI---AFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQ-LLASITVIY----SRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELD-----TENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            WN   Q+P     ++LCF     +W+P ++LW+   IY+        +I+R+   +    ++FK+ ++   A IL +   N    +      +   P L + P +   +     +L  +  +KG+ SSGVLF YWLL  +L  I  +       +R+   H    +  ++      LV    +L+C  D   F        F +D   +QPL               PCPE   SF SK  F W +GL+ +GY++ L  KDL++L   ++ + +V+ +E +W R             L    G +S   P      ETE          + ++ +    LRA++      ++L  +  V  D   FA P++L LF+ F+ + N   W G+LLA+ +F  + ++++  QQ+ +   V  MR RTA+ G++YRK L LSS SRK +  G++VNL+SVD Q+L +   +L+ LW   + I +   +LWQ LGPS L  VA+ + L+P+N  I  K    Q +QM+ K +R +L + +L  ++ +K + WE++F + + +IR  E   L+++T L +VS V++  + FLVAL  F   TL +  + + A KAFV+L++ +IL+   + LP  +   +QA VS  R+  FL  +E+D       N   S  D   + + +GTF+W +   P L  IN+ VP+G L+AVVG VG+GK+SL+SAL+GEL KV G V   GS+ Y+PQ+AW +N S+ +N+ F + L      +V++ACAL  D+   PAG  T IGE+G+NLSGGQKQR+SLARAVY+  ++YLLDDPL+A+D+HV + +F QVIGPSGLL   TRILVTH L  LP+ D+I V+ +G ++E G++ +LL+ NG+ 
Sbjct:   20 WNQTEQEPAAYHLLSLCFVRAASSWVPPMYLWVLGPIYL-------LYIHRHGRCYLRMSHLFKTKMVLGLALILLY-TFNVAVPLWRIHQGVPQAPELLIHPTVWLTTMSFATFLIHMERRKGVRSSGVLFGYWLLCCILPGINTVQQASAGNFRQEPLHHLATYLCLS------LVVAELVLSCLVDQPPF--------FSED---SQPL--------------NPCPEAEASFPSKAMFWWASGLLWRGYKKLLGPKDLWSLGRENSSEELVSQLEREWRRSC---------NGLPGHKGHSSVGAP------ETE-------AFLQPERSQRGPLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPKLLSLFLEFMGDRNSSAWTGWLLAVLMFAAACLQTLFEQQHMYRAKVLQMRLRTAITGLVYRKVLVLSSGSRKSSAAGDVVNLVSVDIQRLAESIIYLNGLWLLFLWIFVCFVYLWQLLGPSALTAVAVFLSLLPLNFFITKKRGFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWEHAFLERLLHIRGQELSALKTSTLLFSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSILNKAQAFLPFSVHCIVQARVSFDRLAAFLCLEEVDPNGMIASNSRRSSKDR--ISVHNGTFAWSQESPPCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVPQEAWVQNTSVVENVCFRQELDLPWLQKVLDACALGSDVASFPAGVHTPIGEQGMNLSGGQKQRLSLARAVYKKAAIYLLDDPLAALDAHVSQQVFKQVIGPSGLLQGTTRILVTHTLHVLPQADRILVLANGTIAEMGSYQDLLQRNGAL 845

HSP 2 Score: 451.44 bits (1160), Expect = 7.141e-133
Identity = 248/584 (42.47%), Postives = 379/584 (64.90%), Query Frame = 2 
Query: 3011 GGVKFSVFLSYIRS-STYLFSFTVVFSYALYMCCSVGA---NMFLSYWTETGSTNGTQ-NPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            G VK +++LSY+R+  T L ++T+     L++C  V +     +LS W +    +G Q +   +G+  G+ G L   QA+ +     A+  G   AS  L   LL ++ R+P  FF+ TP+G +LNR  K+ DTVDV IP  +R  L  A G++     +++++P  ++A++PL  +Y   Q  Y+ TS QL+R++S + S + SH  E+  G+  +RA++    F  + D + DENQ   +P +V+ RWL   LE +GN ++ ++   AV++++ + +G  G S+S ALQ+T  L ++VR  +DLE+  VAVER+++YA I  EAPW +    A   WP  G++EF ++ +R+RP L L ++ +++ + AGEK+GIVGRTGAGKSSLA  L RL E AEG I ID   IT +GLH LRS+ITIIPQDP+LF G++RMNLD   +H+D  +W+ LE   LK+F+      LQY  +  G++LSVGQKQL+CLARALL+K+++L+LDEATA+VD  T+  +Q+++ R F +CTVL IAHRL ++MD  RV+V+++G+V E  SP  LLA +K +F+ +A ++GLA
Sbjct:  923 GRVKTTIYLSYLRAVGTPLCTYTLF----LFLCQQVASFSQGYWLSLWADDPVVDGRQMHAALRGWVFGLLGCL---QAIGLFASMAAVFLGGARASGLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETDTVDVDIPDKLRSLLTYAFGLLEVGLAVTMATPLAIVAILPLMVLYAGFQSLYVATSCQLRRLESARYSSVCSHMAETFQGSLVVRAFRAQASFTAQHDALMDENQRVSFPKLVADRWLATNLELLGNGLVFVAATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYARIPKEAPWRLPTCAAQPLWPCGGQIEFRDFGLRHRPELPLAVQGVSLKIHAGEKVGIVGRTGAGKSSLAWGLLRLQEAAEGNIWIDGVPITHVGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQEHTDEGIWAALETVQLKAFVTSLPGQLQYECAGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDPGTEMQMQAALERWFTQCTVLLIAHRLRSVMDCARVLVMDEGQVAESGSPAQLLA-QKGLFYRLAHESGLA 1498

HSP 3 Score: 80.4925 bits (197), Expect = 1.704e-14
Identity = 73/267 (27.34%), Postives = 123/267 (46.07%), Query Frame = 2 
Query: 3926 VAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSD-GELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSI 4714
            V+ +R+  +  +E   P  +  S +     D  R+   N +  +       L  +N+ V  G  L +VG  GAGKSSL  AL   +   EG++ I+               +  +PQ+  + + ++  N+  F Q  D   L  VL+   L S +A    G+   + E G NLS GQKQ + LARA+ KK+ + +LD+  AA+D      +   +       +  T + + H L+ +   DR++VL  G + E+ S Q+LL    ++
Sbjct:  595 VSFDRLAAFLCLEEVDPNGMIASNSRRSSKD--RISVHNGTFAWSQESPPCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEG-------------SVAYVPQEAWVQNTSVVENVC-FRQELDLPWLQKVLDACALGSDVASFPAGVHTPIGEQGMNLSGGQKQRLSLARAVYKKAAIYLLDDPLAALDAHVSQQVFKQVIGPSGLLQGTTRILVTHTLHVLPQADRILVLANGTIAEMGSYQDLLQRNGAL 845

HSP 4 Score: 62.3882 bits (150), Expect = 5.439e-9
Identity = 59/222 (26.58%), Postives = 99/222 (44.59%), Query Frame = 2 
Query: 2075 KTEAPVLIN-INMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRV-------------MCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            + E P+ +  +++++  G  V +VG  G+GK+SL   L+       G +               R  I  IPQ       SL+ N+   +   +      +E   L   +  LP   Q E   +G +LS GQKQ + LARA+ +   + +LD+  ++VD   G  +  Q        +  T +L+ H L  +    ++ VM +G V+ESG+  +LL   G F
Sbjct: 1270 RPELPLAVQGVSLKIHAGEKVGIVGRTGAGKSSLAWGLLRLQEAAEGNIWIDGVPITHVGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQEHTDEGIWAALETVQLKAFVTSLPGQLQYECAGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDP--GTEMQMQA-ALERWFTQCTVLLIAHRLRSVMDCARVLVMDEGQVAESGSPAQLLAQKGLF 1488
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. UniProt/SwissProt
Match: sp|Q5F364|MRP1_CHICK (Multidrug resistance-associated protein 1 OS=Gallus gallus OX=9031 GN=ABCC1 PE=2 SV=1)

HSP 1 Score: 772.696 bits (1994), Expect = 0.000e+0
Identity = 406/906 (44.81%), Postives = 583/906 (64.35%), Query Frame = 2 
Query:   47 SLCS-DKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIY---RNRG--KFNIFKSTLIAFILFFHLL---NFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFH---DRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEI-DFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSP--PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            SLCS D S  +  W   + W+T++PD T CFQ T+L W+P ++LW+    Y         F+Y    +RG  + +I      A  L   ++   +   +  E   N++  P   + P +  I+ +L  +L +    KG+ SSGV+  +WL+ LL + TVI+     L  +   + D FR VT    F+L+ V  IL+CF                    E  PL S   +D        PCPE   SFLS++TF W+TGL+I+G+R+PL  KDL++L + DT + IV  +   W +E  + K+          N   S+ K  KS +   E+ +  +       Q+    S  + L+ T G  ++++ +FK A+DLL F  P+IL L I F++N +   W G+     LF+ + ++++I  QY+H C+VTGMR +TA++G+IYRKAL +++++RK +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+Y LW+ LGPSVLAGVA+MI L+PIN ++  K K  Q  QMK KDNRIKLMNEIL+GIK+LKLYAWE +F + +  IR  E ++L+ + YL A+   TW CAPFLVAL TF  +   + +++L A KAFVSL+LFNIL FP+++LP VI   ++A VSLKR+  FL  +ELD +++   P    E  + + + TFSW KT+ P L +IN  VPEGSL+AVVG VG GK+SL+SAL+GE+ K  G V+ +GSI Y+PQQAW +NA+L+DNI+F + +   +Y RVIEACAL  DL++LP GD+TEIGEKG+NLSGGQKQR+SLARAVY +   YL DDPLSAVD+HVGKHIF++VIGP G+L +KTR+LVTH + YLP++D I VM DG +SE G++ ELLK +G+FAEF+RTY
Sbjct:    5 SLCSADASEPFWDWN--LTWHTENPDFTQCFQNTVLVWVPCIYLWVCFPAY---------FLYLRSHDRGYIQMSILNKAKTALGLILWIVCWADLFYSFWERSQNIFRAPFFLISPTVLGITMLLATFLIQHERLKGVQSSGVMMIFWLISLLCA-TVIFRSKIMLALNTDTEVDAFRYVTFCTYFILLLVQLILSCFP-------------------EKPPLFSEAVNDPK------PCPEFSASFLSRITFWWITGLMIQGHRRPLEAKDLWSLNKEDTSEEIVPGLAKNWAKEWAKTKRQPL-------NMLYSSKKQQKSSDSNGEVMEEAEALIIKPSQRSSEASLSKVLYKTFGPYFLMSFLFKAAHDLLMFTGPEILKLLINFVNNKSAPNWQGYFYTGLLFVCACLQTLILHQYFHICFVTGMRLKTAIVGVIYRKALVITNSARKTSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWRNLGPSVLAGVAVMILLVPINAVMAMKTKTYQVAQMKSKDNRIKLMNEILNGIKVLKLYAWELAFREKVLEIRQKELKVLKKSAYLAAMGTFTWVCAPFLVALSTFAVYVKVNKNNILDAQKAFVSLALFNILRFPLNILPMVISSIVEASVSLKRLRVFLSHEELDPDSIIRGPITNAEGSIVVKNATFSWSKTDPPSLNSINFTVPEGSLIAVVGQVGCGKSSLLSALLGEMDKKEGYVVVKGSIAYVPQQAWIQNATLEDNIIFGREMNESRYKRVIEACALLPDLEILPMGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADTYLFDDPLSAVDAHVGKHIFEKVIGPKGILKNKTRVLVTHAVNYLPQMDTILVMTDGEISEMGSYQELLKQDGAFAEFLRTY 866

HSP 2 Score: 644.04 bits (1660), Expect = 0.000e+0
Identity = 321/585 (54.87%), Postives = 434/585 (74.19%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMC---CSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            A+ G VK +V+  Y+++     SF  VF   L+MC    S+ +N +LS WT+    NGTQ        LG+YG+LG  Q + +   + A++ G   AS+ LH  LL N+LR+P SFF+ TP G +++R  K+IDT+D +IP  I++++ +   VIG+  +I +++P   + + PL  +Y + QRFY+ TSRQLKR++S+ RSP+YSHF E+++G S IRA++    FIK+ D+  DENQ A+YP+IV+ RWL   LE +GN ++L + + AV+ R+ +  G  GLS+SY+LQIT  LN++VRMTSDLE++ VAVER+KEYAE+E EA W+IEE+   S WP  G+VEF  + +RYR  LDLVL+N+NI ++ GEK+GIVGRTGAGKSSL L LFR+ E AEG IIID  +I K+GLHDLR KITIIPQDPILFSG++RMNLDPF+QHSD ++W  LE+++LK+F++   + L +  SEGGENLSVGQ+QLVCLARALL+KSK+LVLDEATAAVDLETD+LIQS+I+ QF++CTVLTIAHRLNTIMDY RV+VL++G V E DSP NLL   K +F+SMA D+GLA
Sbjct:  947 AKTGRVKATVYWEYMKAIGLYISFLSVF---LFMCNHIASLASNYWLSLWTDDPVVNGTQQ--YTNVRLGVYGALGISQGIAVFGYSMAVSIGGIFASRHLHLDLLHNVLRSPMSFFERTPSGNLVSRFSKEIDTIDSTIPPIIKMFMGSTFNVIGACIIILLATPIAAVVIPPLGLVYLLVQRFYVATSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQKRFIKQNDMKVDENQKAYYPSIVANRWLAVRLEFVGNCIVLFAALFAVIARNKLSPGLIGLSVSYSLQITAYLNWLVRMTSDLETNIVAVERVKEYAEMEKEAEWSIEETAPASTWPQEGKVEFRGFGLRYREDLDLVLKNINITINGGEKVGIVGRTGAGKSSLTLGLFRINEAAEGEIIIDGINIAKIGLHDLRFKITIIPQDPILFSGSLRMNLDPFDQHSDEDIWRSLELAHLKNFVSSLPDKLNHECSEGGENLSVGQRQLVCLARALLRKSKILVLDEATAAVDLETDNLIQSTIKSQFEECTVLTIAHRLNTIMDYTRVLVLDRGEVVECDSPDNLL-QAKGLFYSMAKDSGLA 1525

HSP 3 Score: 76.6406 bits (187), Expect = 2.112e-12
Identity = 56/212 (26.42%), Postives = 96/212 (45.28%), Query Frame = 2 
Query: 4079 LRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            L ++N  V  G  + +VG+ G GKSSL  AL   ++  EG +++             +  I  +PQ   + + T+  N+    + ++     V+E   L   +     G +  + E G NLS GQKQ V LARA+   +   + D+  +AVD      I   +   +   K  T + + H +N +   D ++V+  G + E+ S Q LL  +
Sbjct:  658 LNSINFTVPEGSLIAVVGQVGCGKSSLLSALLGEMDKKEGYVVV-------------KGSIAYVPQQAWIQNATLEDNIIFGREMNESRYKRVIEACALLPDLEILPMGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADTYLFDDPLSAVDAHVGKHIFEKVIGPKGILKNKTRVLVTHAVNYLPQMDTILVMTDGEISEMGSYQELLKQD 856

HSP 4 Score: 69.3218 bits (168), Expect = 3.014e-10
Identity = 61/219 (27.85%), Postives = 90/219 (41.10%), Query Frame = 2 
Query: 2090 VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-------------SIGYIPQQAWCRNASLQDNILFSKPLINHKYN---RVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            VL NIN+ +  G  V +VG  G+GK+SL   L        G ++  G              I  IPQ     + SL+ N+    P   H      R +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G V E  +   LL+  G F
Sbjct: 1303 VLKNINITINGGEKVGIVGRTGAGKSSLTLGLFRINEAAEGEIIIDGINIAKIGLHDLRFKITIIPQDPILFSGSLRMNL---DPFDQHSDEDIWRSLELAHLKNFVSSLPDKLNHECSEGGENLSVGQRQLVCLARALLRKSKILVLDEATAAVDLETDNLIQSTI---KSQFEECTVLTIAHRLNTIMDYTRVLVLDRGEVVECDSPDNLLQAKGLF 1515
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. UniProt/SwissProt
Match: sp|Q8CG09|MRP1_RAT (Multidrug resistance-associated protein 1 OS=Rattus norvegicus OX=10116 GN=Abcc1 PE=1 SV=2)

HSP 1 Score: 764.607 bits (1973), Expect = 0.000e+0
Identity = 391/899 (43.49%), Postives = 568/899 (63.18%), Query Frame = 2 
Query:   41 FTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDE----KPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
             +S CS   +D  LW   + W+T +PD T CFQ T+L W+P  +LW SC     +  ++    Y      N  K+ L  F+      +   +  E    +   P L + P L  I+ +L  +L +   +KG+ SSG++  +WL+ LL ++ ++ S+       D   D+FR       F LVF+  +L+CF+D                   + PL S    D        PCPE+  SFLS++TF W+TG++++GYRQPL   DL++L + DT + +V  +   W +E  + ++   R         T   KP  S + +   + V+        K + PS  + L+ T G  ++++ ++K  +DL+ FA P+IL L I F+++     W G+L    LF+ + ++++   QY+H C+VTGMR +TAV+G +YRKAL +++++RK +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ + +A+YFLW  LGPSVLAGVA+MI ++P N ++  K K  Q   MK KDNRIKLMNEIL+GIK+LKLYAWE +F+  + NIR +E ++L+ + YL AV   TW C PFLVAL TF  F      ++L A KAFVSL+LFNIL FP+++LP VI   +QA VSLKR+  FL  +EL+ +++E     +      + + + TF+W + E P L  I   +P+G+LVAVVG VG GK+SL+SAL+ E+ KV G V  +GS+ Y+PQQAW +N SL++NILF +PL  H Y  V+EACAL  DL++LP+GD TEIGEKG+NLSGGQKQR+SLARAVY +  +YLLDDPLSAVD+HVGKHIF++V+GP GLL +KTRILVTHG++YLP+VD I VM  G +SE G++ ELL  +G+FAEF+RTY
Sbjct:    3 LSSFCSSDGSD-PLWDWNVTWHTSNPDFTKCFQNTVLTWVPCFYLW-SCFPLYFLYLSRHDRGYIQMTHLNKAKTALGFFLWIICWADLFYSFWERSQGMLLAPVLLVSPTLLGITMLLATFLIQFERRKGVQSSGIMLTFWLVALLCALAILRSKIISALKKDAQVDMFRDSAFYLYFTLVFIQLVLSCFSD-------------------SSPLFSETVRDPN------PCPESSASFLSRITFWWITGMMVQGYRQPLKSSDLWSLNKEDTSEEVVPVLVNNWKKECVKSRKQPVRIVYAPPKDPT---KPKGSSQLDVN-EEVEALIVKSSHKDRDPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPEILELIINFVNDREAPDWQGYLYTALLFVSACLQTLALHQYFHICFVTGMRIKTAVVGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVTLALYFLWLNLGPSVLAGVAVMILMVPFNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMNIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDEKNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERWSIKDGGGMNSITVKNATFTWARDEPPTLNGITFAIPDGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGRPLQEHCYKAVMEACALLPDLEILPSGDLTEIGEKGVNLSGGQKQRVSLARAVYCNSDIYLLDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFVRTY 870

HSP 2 Score: 627.091 bits (1616), Expect = 0.000e+0
Identity = 304/582 (52.23%), Postives = 436/582 (74.91%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTET-GSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A+ G VK SV+ +Y+++     SF  +F +      ++ +N +LS WT+   + NGTQ  +++ F L +YG+LG  Q + +   + A++ G   AS+ LH  LL+N+LR+P SFF+ TP G ++NR  K++DTVD  IP  I++++ +   VIG++ +I +++P   + + PL  +Y+  QRFY+ +SRQLKR++S+ RSP+YSHF E+++G S IRA++  + FI++ D+  DENQ A+YP+IV+ RWL   LE +GN ++L + + AV++R ++ +G  GLS+SY+LQIT  LN++VRM+S++E++ VAVER+KEY+E E EA W I+E+   S WP SGRVEF +Y +RYR  LDLVL+++N+ ++ GEK+GIVGRTGAGKSSL L LFR+ E AEG IIID  +I K+GLH+LR KITIIPQDP+LFSG++RMNLDPF+Q+SD E+W  LE+++LK F++   + L +  +EGGENLSVGQ+QLVCLARALL+K+K+LVLDEATAAVDLETDDLIQS+IR QF+  TVLTIAHRLNTIMDY RV+VL++G ++E  +P  LL  ++ +F+SMA DAGL
Sbjct:  953 AQTGQVKLSVYWNYMKAIGLCISFLSIFLFLCNHVSALASNYWLSLWTDDRPAVNGTQ--ENRNFRLSVYGALGILQGVAVFGYSMAVSIGGIFASRRLHLDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEASWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDSTVLTIAHRLNTIMDYTRVIVLDKGEIRECGAPSELL-QQRGVFYSMAKDAGL 1531

HSP 3 Score: 79.7221 bits (195), Expect = 2.357e-13
Identity = 107/478 (22.38%), Postives = 197/478 (41.21%), Query Frame = 2 
Query: 1370 KETTVGEIVN-----LMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKL---QAKQMKMKDNRIK-----LMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRS-ATYLNAVSAVTWFCAPF-LVALCT--FTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENV-EVSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-------------SIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            + T  G +VN     L +VDS   Q +  F+  L++    ++I            +L    +   +IP  G++   V++     ++Q+K  ++  +       NE L G+ +++      +FE+  + IR  + ++  +   Y  ++ A  W       V  C   F A     S H L+A    +S+S    ++  ++ L  +        V+++R+ ++   ++  +  + E +PP   P    V+  D    + +    VL +IN+ +  G  V +VG  G+GK+SL   L        G ++  G              I  IPQ     + SL+ N+       + +    +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G + E G  +ELL+  G F
Sbjct: 1066 ERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVII------------ILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIR------AFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEASWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTI---RTQFEDSTVLTIAHRLNTIMDYTRVIVLDKGEIRECGAPSELLQQRGVF 1522

HSP 4 Score: 73.9442 bits (180), Expect = 1.286e-11
Identity = 68/278 (24.46%), Postives = 121/278 (43.53%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNL---DPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            LN +  + S +   +V+++R++ +   E   P +IE   +  D      +   N +  +       L  +   +  G  + +VG+ G GKSSL  AL   ++  EG +              L+  +  +PQ   + + ++R N+    P  +H      +V+E   L   +     G    + E G NLS GQKQ V LARA+   S + +LD+  +AVD      I   +       K  T + + H ++ +   D ++V+  G++ E+ S Q LL
Sbjct:  597 LNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIER-WSIKDGGGMNSITVKNATFTWARDEPPTLNGITFAIPDGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVT-------------LKGSVAYVPQQAWIQNDSLRENILFGRPLQEHCYK---AVMEACALLPDLEILPSGDLTEIGEKGVNLSGGQKQRVSLARAVYCNSDIYLLDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELL 857
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. UniProt/SwissProt
Match: sp|O35379|MRP1_MOUSE (Multidrug resistance-associated protein 1 OS=Mus musculus OX=10090 GN=Abcc1 PE=1 SV=1)

HSP 1 Score: 760.37 bits (1962), Expect = 0.000e+0
Identity = 392/902 (43.46%), Postives = 567/902 (62.86%), Query Frame = 2 
Query:   47 SLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFR------KKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVE---VSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            S CS   +D  LW   + W+T +PD T CFQ T+L W+P  +LW SC        ++    Y      N  K+ L  F+      +   +  E    +   P L + P L  I+ +L  +L +L  +KG+ SSG++  +WL+ LL ++ ++ S+       D   D+FR  T    F LV V  +L+CF+D +                   PL S    D      R PCPE+  SFLS++TF W+TG+++ GYRQPL   DL++L + DT + +V  +   W +E  + ++   R      K   K  G +     L   EE      V+        K + PS  + L+ T G  ++++ ++K  +DL+ FA P+IL L I F+++     W G+     LF+ + ++++   QY+H C+V+GMR +TAV+G +YRKAL +++ +RK +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+YFLW  LGPSVLAGVA+MI ++P+N ++  K K  Q   MK KDNRIKLMNEIL+GIK+LKLYAWE +F+  + +IR +E ++L+ + YL AV   TW C PFLVAL TF  F      ++L A KAFVSL+LFNIL FP+++LP VI   +QA VSLKR+  FL  +EL+ +++E   +   +   + + + TF+W + E P L  I   +PEG+LVAVVG VG GK+SL+SAL+ E+ KV G V  +GS+ Y+PQQAW +N SL++NILF  PL  + Y  V+EACAL  DL++LP+GD+TEIGEKG+NLSGGQKQR+SLARAVY +  +YL DDPLSAVD+HVGKHIF++V+GP GLL +KTRILVTHG++YLP+VD I VM  G +SE G++ ELL  +G+FAEF+RTY
Sbjct:    5 SFCSADGSD-PLWDWNVTWHTSNPDFTKCFQNTVLTWVPCFYLW-SCFPLYFFYLSRHDRGYIQMTHLNKTKTALGFFLWIICWADLFYSFWERSQGVLRAPVLLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIISALKKDAHVDVFRDSTFYLYFTLVLVQLVLSCFSDCS-------------------PLFSETVHD------RNPCPESSASFLSRITFWWITGMMVHGYRQPLESSDLWSLNKEDTSEEVVPVLVNNWKKECDKSRKQPVRIVYAPPKDPSKPKGSSQ----LDVNEE------VEALIVKSPHKDREPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPKILELIINFVNDREAPDWQGYFYTALLFVSACLQTLALHQYFHICFVSGMRIKTAVVGAVYRKALLITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYFLWLSLGPSVLAGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMSIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDERNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRSIKSGEGNSITVKNATFTWARGEPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGHPLQENYYKAVMEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNSDIYLFDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFLRTY 869

HSP 2 Score: 626.706 bits (1615), Expect = 0.000e+0
Identity = 306/582 (52.58%), Postives = 433/582 (74.40%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGST-NGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A+ G V+ SV+ +Y+++     +F  +F +      ++ +N +LS WT+     NGTQ   ++ F L +YG+LG  Q   I   + A++ G   AS+ LH  LL N+LR+P SFF+ TP G ++NR  K++DTVD  IP  I++++ +   VIG++ +I +++P   + + PL  +Y+  QRFY+ +SRQLKR++S+ RSP+YSHF E+++G S IRA++  + FI + D+  DENQ A+YP+IV+ RWL   LE +GN ++L + + AV++R ++ +G  GLS+SY+LQIT  LN++VRM+S++E++ VAVER+KEY+E E EAPW I+E+   S WP SGRVEF +Y +RYR  LDLVL+++N+ ++ GEK+GIVGRTGAGKSSL L LFR+ E AEG IIID  +I K+GLH+LR KITIIPQDP+LFSG++RMNLDPF+Q+SD E+W  LE+++LK F++   + L +  +EGGENLSVGQ+QLVCLARALL+K+K+LVLDEATAAVDLETD+LIQS+IR QF+ CTVLTIAHRLNTIMDY RV+VL++G V+E  +P  LL  ++ IF+SMA DAGL
Sbjct:  949 AQTGQVQLSVYWNYMKAIGLFITFLSIFLFLCNHVSALASNYWLSLWTDDPPVVNGTQA--NRNFRLSVYGALGILQGAAIFGYSMAVSIGGIFASRRLHLDLLYNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSELL-QQRGIFYSMAKDAGL 1527

HSP 3 Score: 78.5666 bits (192), Expect = 4.745e-13
Identity = 68/275 (24.73%), Postives = 123/275 (44.73%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            LN +  + S +   +V+++R++ +   E   P +IE     S   +S  V+  N +  +  G    L  +   +  G  + +VG+ G GKSSL  AL   ++  EG +              L+  +  +PQ   + + ++R N+   +   +    +V+E   L   +     G +  + E G NLS GQKQ V LARA+   S + + D+  +AVD      I   +       K  T + + H ++ +   D ++V+  G++ E+ S Q LL
Sbjct:  597 LNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRSIKSGEGNSITVK--NATFTWARGEPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVT-------------LKGSVAYVPQQAWIQNDSLRENILFGHPLQENYYKAVMEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNSDIYLFDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELL 856

HSP 4 Score: 77.411 bits (189), Expect = 1.263e-12
Identity = 108/477 (22.64%), Postives = 193/477 (40.46%), Query Frame = 2 
Query: 1370 KETTVGEIVN-----LMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKL---QAKQMKMKDNRIK-----LMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPF-LVALCT--FTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGD-ELDTENVEVSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-------------SIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            + T  G +VN     L +VDS   Q +  F+  L++    ++I            +L    +   +IP  G++   V++     ++Q+K  ++  +       NE L G+ +++ +  +  F     +++ DE        Y  ++ A  W       V  C   F A     S H L+A    +S+S    ++  ++ L  +        V+++R+ ++   + E   +  E +PP   P    V+  D    + +    VL +IN+ +  G  V +VG  G+GK+SL   L        G ++  G              I  IPQ     + SL+ N+       + +    +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G V E G  +ELL+  G F
Sbjct: 1062 ERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVII------------ILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQ-SDLKVDE----NQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTI---RTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSELLQQRGIF 1518
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. UniProt/SwissProt
Match: sp|Q864R9|MRP1_MACFA (Multidrug resistance-associated protein 1 OS=Macaca fascicularis OX=9541 GN=ABCC1 PE=1 SV=1)

HSP 1 Score: 753.051 bits (1943), Expect = 0.000e+0
Identity = 381/896 (42.52%), Postives = 562/896 (62.72%), Query Frame = 2 
Query:   50 LCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSP----PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
             CS   +D  LW   + W T +PD T CFQ T+L W+P  +LW +C  +  +  ++    Y      N  K+ L   +      +   +  E    ++  P   + P L  I+ +L  +L +L  +KG+ SSG++  +WL+ LL ++ ++ S+       D   DLFR +T    F LV +  +L+CF+D +                   PL S    D        PCPE+  SFLS++TF W+TGL+++GYRQPL   DL++L + DT + +V  +   W +E  + ++   +     ++             EE E   V++          +PS  + L+ T G  ++++  FK  +DL+ F+ P+IL L I F+++     W G+     LF+ + +++++  QY+H C+V+GMR +TAVIG +YRKAL +++ +RK +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+Y LW+ LGP +LAGVA+M+ ++P+N ++  K K  Q   MK KDNRIKLMNEIL+GIK+LKLYAWE +F+  +  IR +E ++L+ + YL AV   TW C PFLVALCTF  +     ++VL A KAFVSL+LFNIL FP+++LP VI   +QA VSLKR+  FL  +EL+ +++E  P     D   + + + TF+W +++ P L  I   +PEG+LVAVVG VG GK+SL+SAL+ E+ KV G V  +GS+ Y+PQQAW +N SLQ+NILF   L    Y  VI+ACAL  DL++LP+GD+TEIGEKG+NLSGGQKQR+SLARAVY +  +YL DDPLSAVD+HVGKHIF+ VIGP G+L +KTRILVTH ++YLP+VD I VM  G +SE G++ ELL  +G+FAEF+RTY
Sbjct:    6 FCSADGSD-PLWDWNVTWYTSNPDFTKCFQNTVLVWVPCFYLW-ACFPFYFLYLSRHDRGYIQMTLLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIMTALKEDVQVDLFRDMTFYVYFSLVLIQLVLSCFSDRS-------------------PLFSETIHDPN------PCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKDSSKVDANEEVEALIVKSPQKEW-----NPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPEILKLLINFVNDTKAPDWQGYFYTALLFVAACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWRNLGPPILAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALCTFAVYVTIDKNNVLDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGDTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVALKGSVAYVPQQAWIQNDSLQENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTY 869

HSP 2 Score: 631.713 bits (1628), Expect = 0.000e+0
Identity = 305/581 (52.50%), Postives = 432/581 (74.35%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A+ G VK SV+  Y+++     SF  +F +      ++ +N +LS WT+    NGTQ  +     L +YG+LG  Q + +   + A++ G  LAS+ LH  LL +ILR+P SFF+ TP G ++NR  K++DTVD  IP  I++++ +   VIG+  VI +++P   + + PL  +Y+  QRFY+ +SRQLKR++S+ RSP+YSHF E+++G S IRA++  + FI + D+  DENQ A+YP+IV+ RWL   LE +GN ++L + + AV++R ++ +G  GLS+SY+LQ+T  LN++VRM+S++E++ VAVER+KEY+E E EAPW I+E+   S+WP  GRVEF NY +RYR  LD VLR++N+ ++ GEK+GIVGRTGAGKSSL L LFR+ E AEG IIID  +I ++GLHDLR KITIIPQDP+LFSG++RMNLDPF+Q+SD E+W+ LE+++LK F++   + L +  +EGGENLSVGQ+QLVCLARALL+K+K+LVLDEATAAVDLETDDLIQS+IR QF+ CTVLTIAHRLNTIMDY RV+VL++G ++E  +P +LL  ++ +F++MA DAGL
Sbjct:  953 AQTGQVKLSVYWDYMKAIGLFISFLSIFLFICNHVAALASNYWLSLWTDDPIVNGTQ--EHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSNWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIARIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLL-QQRGLFYNMARDAGL 1530

HSP 3 Score: 79.7221 bits (195), Expect = 2.356e-13
Identity = 66/280 (23.57%), Postives = 126/280 (45.00%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKS 4711
            LN +  + S +   +V+++R++ +   E   P +IE      D  D+  +   N +  +       L  +   +  G  + +VG+ G GKSSL  AL   ++  EG +              L+  +  +PQ   + + +++ N+    Q  +    SV++   L   +     G +  + E G NLS GQKQ V LARA+   + + + D+  +AVD      I  ++   +   K  T + + H ++ +   D ++V+  G++ E+ S Q LLA + +
Sbjct:  596 LNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPV-KDGGDTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVA-------------LKGSVAYVPQQAWIQNDSLQENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGA 861

HSP 4 Score: 71.633 bits (174), Expect = 5.973e-11
Identity = 89/382 (23.30%), Postives = 154/382 (40.31%), Query Frame = 2 
Query: 1640 NEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPF-LVALCT--FTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGD-ELDTENVEVSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-------------SIGYIPQQAWCRNASLQDNILFSKPLINHKYNRV---IEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIR 2713
            NE L G+ +++ +  +  F     +++ DE        Y  ++ A  W       V  C   F A     S H L+A    +S+S    ++  ++ L  +        V+++R+ ++   + E   +  E +PP   P    V+  +    + +    VL +IN+ +  G  V +VG  G+GK+SL   L        G ++  G              I  IPQ     + SL+ N+    P   +    V   +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G + E G  ++LL+  G F    R
Sbjct: 1156 NETLLGVSVIRAFEEQERFIHQ-SDLKVDE----NQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSNWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIARIGLHDLRFKITIIPQDPVLFSGSLRMNL---DPFSQYSDEEVWTSLELAHLKGFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTI---RTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYNMAR 1526
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. UniProt/SwissProt
Match: sp|O15438|MRP3_HUMAN (Canalicular multispecific organic anion transporter 2 OS=Homo sapiens OX=9606 GN=ABCC3 PE=1 SV=3)

HSP 1 Score: 748.043 bits (1930), Expect = 0.000e+0
Identity = 390/903 (43.19%), Postives = 564/903 (62.46%), Query Frame = 2 
Query:   47 SLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLY-------PPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVE---VSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            +LC         W   +  +T++PD+T CFQ ++L W+P ++LW++   Y+  L        R+  +  I  S L    +   +L +C + ++   + +       P P  ++ P++  ++ +L   L +    +G+ SSGVL  +W L ++ +I    S+    K      D FR  T    F LV  + IL CF +   F  ++ ++                P+         P PE    FLS+L F W T + I GYR PL  KDL++L+E D    +V  +   W ++ ++  + K            ++  P K+   E E+            + + PSFL+AL  T G  ++++  FK+  DLL+F  PQ+L + I FI NP    W GFL+A  +FL SM++S+I Q YYH  +VTG++ RT ++G+IYRKAL ++++ ++ +TVGEIVNLMSVD+Q+  D+  FL++LW+AP+ I++AIYFLWQ LGPSVLAGVA M+ LIP+NG +  K++  Q KQMK+KD+RIKLM+EIL+GIK+LKLYAWE SF + ++ IR  E ++LR+A YL+  +  TW C+PFLV L T   +     ++VL A KAFVS+SLFNIL  P++MLP +I    QA VSLKRI +FL  +ELD ++VE   +SP     + I  GTF+W +   P L +++++VP+G+LVAVVG VG GK+SL+SAL+GE+ K+ G+V  +GS+ Y+PQQAW +N +LQ+N+LF K L   +Y + +EACAL  DL++LP GDQTEIGEKGINLSGGQ+QR+SLARAVY D  ++LLDDPLSAVDSHV KHIFD VIGP G+L+ KTR+LVTHG+++LP+ D I V+ DG VSE G +  LL+ NGSFA F+  Y
Sbjct:    3 ALCGSGELGSKFWDSNLSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLYL--------RHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRAPAPVFFVTPLVVGVTMLLATLLIQYERLQGVQSSGVLIIFWFLCVVCAIVPFRSKILLAKAEGEISDPFRFTTFYIHFALVLSALILACFREKPPFFSAKNVD----------------PN---------PYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLWSLKEEDRSQMVVQQLLEAWRKQEKQTARHK------------ASAAPGKNASGEDEV------LLGARPRPRKPSFLKALLATFGSSFLISACFKLIQDLLSFINPQLLSILIRFISNPMAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFMDLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVERKTISP--GYAITIHSGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFLCNY 852

HSP 2 Score: 619.002 bits (1595), Expect = 0.000e+0
Identity = 315/582 (54.12%), Postives = 411/582 (70.62%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            A IG V+ SVF  Y ++     +  +   Y      ++GAN++LS WT     +  QN  S    LG+Y +LG  Q   +++   A+A G   A++ LH  LL N +R+P SFFDTTP GRILN   KDI  VD  +   I + L +    I ++ VI  S+P F + ++PL  +Y + QRFY  TSRQLKR++S+ RSPIYSHF E++ GAS IRAY  S DF    D   D NQ + YP I+S RWL   +E +GN V+L + + AV+ RS++  G  GLS+SY+LQ+T  LN+M+RM SDLES+ VAVER+KEY++ E+EAPW +E S+    WP  G VEF NYSVRYRPGLDLVLR+L++ V  GEK+GIVGRTGAGKSS+ L LFR++E A+G I ID  ++  +GLHDLRS++TIIPQDPILFSGT+RMNLDPF  +S+ ++W  LE+S+L +F++    GL +  SEGGENLSVGQ+QLVCLARALL+KS++LVLDEATAA+DLETD+LIQ++IR QF  CTVLTIAHRLNTIMDY RV+VL++G V E DSP NL+A  + IF+ MA DAGLA
Sbjct:  949 AAIGTVELSVFWDYAKAVGLCTTLAICLLYVGQSAAAIGANVWLSAWTNDAMADSRQNNTS--LRLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHNKIRSPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLESVSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNRWLSIGVEFVGNCVVLFAALFAVIGRSSLNPGLVGLSVSYSLQVTFALNWMIRMMSDLESNIVAVERVKEYSKTETEAPWVVEGSRPPEGWPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGSYSEEDIWWALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIA-ARGIFYGMARDAGLA 1527

HSP 3 Score: 79.337 bits (194), Expect = 3.111e-13
Identity = 97/415 (23.37%), Postives = 180/415 (43.37%), Query Frame = 2 
Query: 3494 FLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCD-IMTDENQM----AWYPNIVSYRWL-QFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKS 4711
            F++ L+PL     +A +   +  +Q+K  DS  R  + S   E + G   ++ Y     F+K+ + I   E Q+    A+     ++ W+   +L T+    I L   + V   + + +  A +S+S    +   LN + ++ S+L   +V+++RI+++   E   P ++E       +     +   + +  +   L   L +L+I V  G  + +VG  G GKSSL  AL   +E  EG +              ++  +  +PQ   + + T++ N+      +       LE   L + +     G Q  + E G NLS GQ+Q V LARA+   + + +LD+  +AVD      I   +          T + + H ++ +   D ++VL  G+V E+     LL    S
Sbjct:  458 FMVLLIPLNGA--VAVKMRAFQVKQMKLKDS--RIKLMS---EILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTL----ITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVERKTISPGYA----ITIHSGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKV-------------HMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGS 844

HSP 4 Score: 58.9214 bits (141), Expect = 4.875e-7
Identity = 54/224 (24.11%), Postives = 94/224 (41.96%), Query Frame = 2 
Query: 2090 VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRV---IEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIR 2713
            VL ++++ V  G  V +VG  G+GK+S+   L   L    G +               R  +  IPQ     + +L+ N+    P  ++    +   +E   L   +   PAG   +  E G NLS GQ+Q + LARA+ +   + +LD+  +A+D      I   +        + T + + H L  +    ++ V+  G V+E  +   L+   G F    R
Sbjct: 1305 VLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNL---DPFGSYSEEDIWWALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATI---RTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIAARGIFYGMAR 1522
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BLAST of Canalicular multispecific organic anion transporter 1 vs. TrEMBL
Match: A0A267GTI5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig016190g1 PE=4 SV=1)

HSP 1 Score: 1592.4 bits (4122), Expect = 0.000e+0
Identity = 845/1589 (53.18%), Postives = 1134/1589 (71.37%), Query Frame = 2 
Query:   26 MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYS--RYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTD--SEQINNFQQDFDETQPLLSLIPDDKTIPI-------NRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVS----PPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYLXXXXXXXXXXXXXXXXXXXXXXXXHTISRLSSNIDXXXXXXXXXXXXNPLTDSRRSHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVAEIGGVKFSVFLSYIRSSTYL-FSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            +G  ++ SLC   S DW  W D +  NT DPD+TLCFQYT+L+W+P +FL      ++  L    S   R    FN+ K  L+  ++   +++F   ++++ S L  P  +Y+ PIL  +  +L++++    Y+KG+HSSG+LF +WLL+LL SI ++ S  RY  ++  + D FR VT +       V F+   F D          +  ++ +  DET+ LL     +K  P        N  PCPE   SFLS+++F WLTG++I+GY++ LT  DL+AL + DTC  IV  ++  W +E  +  ++    + +  N  TSN  P+     +   +  ++  +  +     PSFLR L    G+PY +AG++K+AYDL+ FAQPQ+L L I FI N + Y W G+ LA+ LFL+++ ++ IFQQYYHG Y TGMR RTAVI  +YRKAL+LSS++RK  TVGEIVNLMSVD+QKLQD P+FLH LW API I +A+YFLW +LGPSVLAG+ +M+ LIP+NGII S+++KLQ  QMK KD RIK+MNE+L+GIK+LKLYAWE  F++ ++  R+ E ++L +A YLNA SA+TWFCAPFLVAL TF  + LSS  ++L ANKAFVSL+LFNI++FP+S+LPG I Y + + VS+ RI  FL  DE+D + V+ S       E PV++  G F WG  E  VL ++N+++P G LVA+VG+VG+GKTSL+SAL+GEL K SG V   G++GY+PQQAWC+NA+L+DNI F K      + RVI ACAL  D+K+LP G +TEIGEKGINLSGGQKQRISLARAVY D  +Y LDDPLSAVDSHVGKHIF+QV+GPSGLLS+KTR+LVTHG+++LPK+D I V+KDG+VSE GT++ELL++NG FAEFI+ YL   EEE+ EE+ ++E++ L+ EL+ TIS LS +             +  L   R+SH   +  R     SV  ++   ++    ++ + EE  +E G VK SVF SY+RS  +  F+F+V+ +YAL++ C VG N++LS W++  + NGTQ+   +   LG+YG++G GQA+F+L++N  +A GT+ ASK LH+ +L NI++ P SFFD TP+GRI+NR GKDIDTVDVSIP T+RIWLMT  GV+G+I +I I++  F+L  +PL  +YY AQRFY+ TSRQLKRIDS++RSPIYSHFQE+IVGAS IRA+    DF+ K D + D NQMAWYP+IVS RWLQ  LE IGN VIL + V AV +R +I +G AGL++SYALQ+T  LNY+VRMT DLE++ VAVERIKEY E+ +EAPW    ++  S WPDSGRVEF NYSVRYRPGLDLVLR++   V  GEK+GIVGRTGAGKSSL LALFR++EPA G I ID  DI  LGLHDLRSK+TIIPQDP+LFSG++R NLDP  +HSD E+W  +E+++LK F+A    GL+++ SEGGEN+SVGQ+QLVCLARALL+K+K+LVLDEATAA+DLETDDLIQ +IRR+FK C+VLTIAHRLNTI+DYD+++VL++G VKE D+P+ LL N ++IF+ M  DAGL
Sbjct:   13 LGAIYWESLCGSASLDWAFWSDDLTVNTNDPDLTLCFQYTMLHWLPAVFLLCVSAFHLRDLRRMQSKPGRGVSLFNLAKCVLLLPMMLLMVMDFFRAVTDASSGLVTPAVMYVYPILMLLVLLLVLFITYYEYRKGVHSSGLLFLFWLLELLCSIVILRSKIRYESMQLPNADAFRLVTWSTFVAFAAVQFVAQLFVDRGALAQHGGSRGRSYNETTDETRSLLQRNEPEKMRPYMKRFVKHNLEPCPELSSSFLSQISFYWLTGMIIRGYKRALTGDDLWALLDRDTCGYIVPLLQKFWKQEQAKAGKSH---QFKYTNQMTSNGLPVAGGRPDGYQN-AEHVASRPDTATYKPSFLRVLGKVFGWPYFIAGIWKLAYDLINFAQPQLLSLLILFIQNGDPYEWRGYFLAVALFLVALFKTFIFQQYYHGTYTTGMRLRTAVIAAVYRKALRLSSSARKNKTVGEIVNLMSVDAQKLQDAPAFLHQLWGAPIIIALALYFLWLQLGPSVLAGLFVMVLLIPVNGIIASRIRKLQISQMKWKDQRIKVMNEVLNGIKVLKLYAWEAFFDKGVREKRDQELKLLLAAAYLNAASAITWFCAPFLVALATFAVYVLSSPENILDANKAFVSLTLFNIMNFPLSILPGAITYLVTSLVSVGRITSFLNADEVDPDAVDTSGHANDSHEFPVQVHKGDFKWGPDEPLVLKDVNLKIPNGKLVAIVGSVGAGKTSLVSALLGELVKTSGSVSVTGTVGYVPQQAWCQNATLRDNITFGKAFQKTTFERVISACALKPDIKILPGGLETEIGEKGINLSGGQKQRISLARAVYSDTDLYFLDDPLSAVDSHVGKHIFEQVLGPSGLLSNKTRLLVTHGISFLPKMDLIVVLKDGSVSEVGTYSELLQHNGGFAEFIQQYL---EEEDDEEEGDEETQSLRAELRRTISYLSGS---------EMSDAEGLRSRRQSHFSGAPSRRRSKVSVTLDDEANKVAADGRQLIQEES-SETGSVKLSVFKSYVRSFGFGNFAFSVL-TYALFIACQVGQNLWLSEWSQDEAINGTQDTALRDLRLGVYGAIGGGQAIFVLLQNIGIALGTYWASKVLHDDILDNIMKTPLSFFDITPIGRIINRFGKDIDTVDVSIPLTLRIWLMTFGGVVGTIIIIGITTKEFILLFIPLLVLYYFAQRFYVCTSRQLKRIDSVRRSPIYSHFQETIVGASCIRAFGKQQDFVDKSDYLVDWNQMAWYPSIVSNRWLQISLEGIGNFVILFTAVFAVASRYSINAGLAGLAVSYALQVTSSLNYVVRMTCDLETYIVAVERIKEYVEVPTEAPWYNNAARPRSGWPDSGRVEFKNYSVRYRPGLDLVLRDICAAVQPGEKVGIVGRTGAGKSSLTLALFRILEPAGGRIEIDGVDIASLGLHDLRSKLTIIPQDPVLFSGSLRYNLDPAEEHSDAEVWKSIELAHLKEFVAAQPAGLEFVCSEGGENMSVGQRQLVCLARALLRKTKILVLDEATAAIDLETDDLIQQTIRREFKACSVLTIAHRLNTIIDYDKILVLDKGLVKEFDAPKVLLDNPRTIFYGMVRDAGL 1583
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BLAST of Canalicular multispecific organic anion transporter 1 vs. TrEMBL
Match: A0A2A3EBU1 (Multidrug resistance-associated protein OS=Apis cerana cerana OX=94128 GN=APICC_09479 PE=4 SV=1)

HSP 1 Score: 1273.46 bits (3294), Expect = 0.000e+0
Identity = 675/1361 (49.60%), Postives = 922/1361 (67.74%), Query Frame = 2 
Query:  695 PDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQR---VKQTK--FRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWG--KTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYLXXXXXXXXXXXXXXXXXXXXXXXXHTISR-LSSNIDXXXXXXXXXXXXNPLTDSRRSHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVAEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGST--NGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            P     P    PCPE + SF  K+ F+W   +  KG+++PL   DL+++   DT   IV   E  W +  Q+   V+ TK  FRK    Q  F + YK   S                        S L  L    G  ++   V K   D++TF  PQIL L I FI   ++ +W G+  A+ L + ++ ++++  QY+H  ++ G+R RTA+I  IYRKAL++S+ +RKE+TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ IV+A+YFLW  LGP+VLAG+A+++ LIPIN +I ++VK LQ +QMK KD R+KLMNE+L+GIK+LKLYAWE SFE+ I  IR  E ++L+   YLN+ ++  W  APFLV+L +F  + L   ++ L + KAFVSLSLFNIL FP+S+LP +I   +QAYVS+KRINKF+  +ELD  NV+    +   + I +GTF W     + P L NIN++V +G LVAVVGTVGSGK+SL+SAL+GE+ K++GRV  +GSI Y+ QQAW +NASLQDN+LF K L  + YNRVIEACALT DLKVLPAGDQTEIGEKGINLSGGQKQR+SLARAVY D  +Y LDDPLSAVDSHVGKHIF+ VIG SGLL  KTRILVTHG+TYLP+VD I V+KDG ++E GT+ +LL+  G+F+EF+  +L            E  +    +   H I + L S I S    QK +   + +++S+      +  +          +    L      +LIE E  E G VK+ V+  Y +S  +  S + +   A++   S+G+N +LS W++   T  N T +   Q  YLG+YG LG GQA+   + + A   G +LA++ +H ++L+ ++RAP +FFDTTP GRI++R  KD+D +D S+P  I   +     VI ++ VIS S+P F+  ++P++ +YY  QR Y+ +SRQLKR++S+ RSPIYSHF E++ GA  IRA+ V + FI + +   D NQ+ +YP+I++ RWL   LE +GNL+I  + + AV+ + T+ SG  GLS+SYALQ+T  LN++VRMTSD+E++ VAVERIKEY E   EA W   +     +WP  GRVEF +Y VRYR  L+LVLR L+  +  GEK+GIVGRTGAGKSSL LALFR+IE A+G I ID+ DI KLGLHDLRS++TIIPQDP+LFSG++R+NLDPFN ++D E+W  LE ++LKSFI     GL Y VSEGGENLS+GQ+QL+CLARALL+K+KVL+LDEATA+VDLETDDLIQ +IR++FK CT+LTIAHRLNTI+D DR++VL+ GR+ E DSP++LL N  S+F S+A DAGLA
Sbjct:  187 PKYSKYPRAEKPCPEQKSSFPGKIFFSWFDSMAWKGFKKPLEITDLWSINPEDTAKEIVPKFEKYWKKNLQKRNNVQNTKASFRKG-SGQVNFNNEYKKKTS------------------------SVLPPLCKAFGATFLFGAVLKFIQDIITFVSPQILQLLIDFIKG-HEPLWKGYFYAVLLLITAIFQTLVLSQYFHRMFLVGLRIRTALIAAIYRKALRMSNAARKESTVGEIVNLMSVDAQRFMDLTAYINMIWSAPLQIVLALYFLWDILGPAVLAGLAVLLILIPINVLITNRVKTLQIRQMKHKDERVKLMNEVLNGIKVLKLYAWEPSFEEQILKIRTKEIKVLKETAYLNSGTSFIWSFAPFLVSLVSFATYVLIDENNRLDSTKAFVSLSLFNILRFPLSILPMMIGNMVQAYVSVKRINKFMNTEELDPNNVQHDSSESYTLLIENGTFIWDMENIDRPTLRNINLQVEQGQLVAVVGTVGSGKSSLLSALLGEMEKINGRVNTKGSIAYVSQQAWIQNASLQDNVLFGKSLHKNLYNRVIEACALTPDLKVLPAGDQTEIGEKGINLSGGQKQRVSLARAVYNDSDIYFLDDPLSAVDSHVGKHIFENVIGSSGLLKKKTRILVTHGITYLPEVDNIIVLKDGEITEVGTYKQLLEKRGAFSEFLVQHL-----------QEVHADGESEADLHEIKQHLESTIGSNELQQKLTRGKSRMSESQSESGSIADRKSLNGSLKSNIKEAKLLSPKSGGKLIEVEKTETGSVKWRVYSHYFKSIGWFLSISTIIMNAIFQGFSIGSNTWLSMWSDDNLTDVNNTVDHVKQNMYLGVYGGLGLGQAMTSFLCDLAPQLGCWLAARQMHIMMLRVVMRAPLTFFDTTPTGRIISRFAKDVDVLDTSLPQQISDSIYCLFEVIATLVVISFSTPIFISVIIPISVIYYFVQRLYVASSRQLKRLESVSRSPIYSHFSETVSGAQMIRAFGVQERFINESESKVDFNQVCYYPSIIANRWLAVRLEMVGNLIIFFAALFAVLNKDTVSSGLVGLSVSYALQVTQTLNWLVRMTSDVETNIVAVERIKEYGETPQEASWKNPDYTPPKEWPVQGRVEFKDYKVRYREDLELVLRGLSFSIKGGEKVGIVGRTGAGKSSLTLALFRIIEAADGQIFIDDIDIAKLGLHDLRSRLTIIPQDPVLFSGSLRINLDPFNCYTDDEVWRALEHAHLKSFIKNLPNGLLYEVSEGGENLSIGQRQLICLARALLRKTKVLILDEATASVDLETDDLIQQTIRQEFKDCTILTIAHRLNTILDSDRIIVLDNGRIVEYDSPESLLRNSSSLFSSIAKDAGLA 1510
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BLAST of Canalicular multispecific organic anion transporter 1 vs. TrEMBL
Match: A0A1I8GQF2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 870.922 bits (2249), Expect = 0.000e+0
Identity = 459/914 (50.22%), Postives = 628/914 (68.71%), Query Frame = 2 
Query:   26 MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYS--RYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTD--SEQINNFQQDFDETQPLLSLIPDDKTIPI-------NRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVS----PPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYL 2722
            +G  ++ SLC   S DW  W D +  NT DPD+TLCFQYT+L+W+P +FL      ++  L    S   R    FN+ K  L+  ++   +++F   ++++ S L  P  +Y+ PIL  +  +L++++    Y+KG+HSSG+LF +WLL+LL SI ++ S  RY  ++  + D FR VT +       V F+   F D          +  ++ +  DET+ LL     +K  P        N  PCPE   SFLS+++F WLTG++I+GY++ LT  DL+AL + DTC  IV  ++  W +E  +  ++    + +  N  TSN  P+     +   +  ++  +  +     PSFLR L    G+PY +AG++K+AYDL+ FAQPQ+L L I FI N + Y W G+ LA+ LFL+++ ++ IFQQYYHG Y TGMR RTAVI  +YRKAL+LSS++RK  TVGEIVNLMSVD+QKLQD P+FLH LW API I +A+YFLW +LGPSVLAG+ +M+ LIP+NGII S+++KLQ  QMK KD RIK+MNE+L+GIK+LKLYAWE  F++ ++  R+ E ++L +A YLNA SA+TWFCAPFLVAL TF  + LSS  ++L ANKAFVSL+LFNI++FP+S+LPG I Y + + VS+ RI  FL  DE+D + V+ S       E PV++  G F WG  E  VL ++N+++P G LVA+VG+VG+GKTSL+SAL+GEL K SG V   G++GY+PQQAWC+NA+L+DNI F K      + RVI ACAL  D+K+LP G +TEIGEKGINLSGGQKQRISLARAVY D  +Y LDDPLSAVDSHVGKHIF+QV+GPSGLLS+KTR+LVTHG+++LPK+D I V+KDG+VSE GT++ELL++NG FAEFI+ YL
Sbjct:   13 LGAIYWESLCGSASLDWAFWSDDLTVNTNDPDLTLCFQYTMLHWLPAVFLLCVSAFHLRDLRRMQSKPGRGVSLFNLAKCVLLLPMMLLMVMDFFRAVTDASSGLVTPAVMYVYPILMLLVLLLVLFITYYEYRKGVHSSGLLFLFWLLELLCSIVILRSKIRYESMQLPNADAFRLVTWSTFVAFAAVQFVAQLFVDRGALAQHGGSRGRSYNETTDETRSLLQRNEPEKMRPYMKRFVKHNLEPCPELSSSFLSQISFYWLTGMIIRGYKRALTGDDLWALLDRDTCGYIVPLLQKFWKQEQAKAGKSH---QFKYTNQMTSNGLPVAGGRPDGYQN-AEHVASRPDTATYKPSFLRVLGKVFGWPYFIAGIWKLAYDLINFAQPQLLSLLILFIQNGDPYEWRGYFLAVALFLVALFKTFIFQQYYHGTYTTGMRLRTAVIAAVYRKALRLSSSARKNKTVGEIVNLMSVDAQKLQDAPAFLHQLWGAPIIIALALYFLWLQLGPSVLAGLFVMVLLIPVNGIIASRIRKLQISQMKWKDQRIKVMNEVLNGIKVLKLYAWEAFFDKGVREKRDQELKLLLAAAYLNAASAITWFCAPFLVALATFAVYVLSSPENILDANKAFVSLTLFNIMNFPLSILPGAITYLVTSLVSVGRITSFLNADEVDPDAVDTSGHANDSHEFPVQVHKGDFKWGPDEPLVLKDVNLKIPNGKLVAIVGSVGAGKTSLVSALLGELVKTSGSVSVTGTVGYVPQQAWCQNATLRDNITFGKAFQKTTFERVISACALKPDIKILPGGLETEIGEKGINLSGGQKQRISLARAVYSDTDLYFLDDPLSAVDSHVGKHIFEQVLGPSGLLSNKTRLLVTHGISFLPKMDLIVVLKDGSVSEVGTYSELLQHNGGFAEFIQQYL 922

HSP 2 Score: 683.33 bits (1762), Expect = 0.000e+0
Identity = 331/531 (62.34%), Postives = 421/531 (79.28%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYL-FSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCT 4591
            +E G VK SVF SY+RS  +  F+F+V+ +YAL++ C VG N++LS W++  + NGTQ+   +   LG+YG++G GQA+F+L++N  +A GT+ ASK LH+ +L NI++ P SFFD TP+GRI+NR GKDIDTVDVSIP T+RIWLMT  GV+G+I +I I++  F+L  +PL  +YY AQRFY+ TSRQLKRIDS++RSPIYSHFQE+IVGAS IRA+    DF+ K D + D NQMAWYP+IVS RWLQ  LE IGN VIL + V AV +R +I +G AGL++SYALQ+T  LNY+VRMT DLE++ VAVERIKEY E+ +EAPW    ++  S WPDSGRVEF NYSVRYRPGLDLVLR++   V  GEK+GIVGRTGAGKSSL LALFR++EPA G I ID  DI  LGLHDLRSK+TIIPQDP+LFSG++R NLDP  +HSD E+W  +E+++LK F+A    GL+++ SEGGEN+SVGQ+QLVCLARALL+K+K+LVLDEATAA+DLETDDLIQ +IRR+FK C+
Sbjct:  978 SETGSVKLSVFKSYVRSFGFGNFAFSVL-TYALFIACQVGQNLWLSEWSQDEAINGTQDTALRDLRLGVYGAIGGGQAIFVLLQNIGIALGTYWASKVLHDDILDNIMKTPLSFFDITPIGRIINRFGKDIDTVDVSIPLTLRIWLMTFGGVVGTIIIIGITTKEFILLFIPLLVLYYFAQRFYVCTSRQLKRIDSVRRSPIYSHFQETIVGASCIRAFGKQQDFVDKSDYLVDWNQMAWYPSIVSNRWLQISLEGIGNFVILFTAVFAVASRYSINAGLAGLAVSYALQVTSSLNYVVRMTCDLETYIVAVERIKEYVEVPTEAPWYNNAARPRSGWPDSGRVEFKNYSVRYRPGLDLVLRDICAAVQPGEKVGIVGRTGAGKSSLTLALFRILEPAGGRIEIDGVDIASLGLHDLRSKLTIIPQDPVLFSGSLRYNLDPAEEHSDAEVWKSIELAHLKEFVAAQPAGLEFVCSEGGENMSVGQRQLVCLARALLRKTKILVLDEATAAIDLETDDLIQQTIRREFKACS 1507

HSP 3 Score: 79.337 bits (194), Expect = 9.342e-11
Identity = 70/281 (24.91%), Postives = 121/281 (43.06%), Query Frame = 2 
Query: 3869 ITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLAN 4702
            + G + Y+V       +  V+V RI  +   +   P  ++ S  H++      V+      ++ P   LVL+++N+ +  G+ + IVG  GAGK+SL  AL   +    G++ +                +  +PQ     + T+R N+             V+    LK  I     GL+  + E G NLS GQKQ + LARA+   + +  LD+  +AVD      I   +          T L + H ++ +   D ++VL+ G V E+ +   LL +
Sbjct:  651 LPGAITYLV-------TSLVSVGRITSFLNADEVDPDAVDTS-GHANDSHEFPVQVHKGDFKWGPDEPLVLKDVNLKIPNGKLVAIVGSVGAGKTSLVSALLGELVKTSGSVSVTG-------------TVGYVPQQAWCQNATLRDNITFGKAFQKTTFERVISACALKPDIKILPGGLETEIGEKGINLSGGQKQRISLARAVYSDTDLYFLDDPLSAVDSHVGKHIFEQVLGPSGLLSNKTRLLVTHGISFLPKMDLIVVLKDGSVSEVGTYSELLQH 910

HSP 4 Score: 65.4698 bits (158), Expect = 1.314e-6
Identity = 59/203 (29.06%), Postives = 95/203 (46.80%), Query Frame = 2 
Query: 1955 VSLKRINKFL-VGDELDTENVEVSP----PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG----SIGY---------IPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVD 2509
            V+++RI +++ V  E    N    P    PD   V+  + +  +      VL +I   V  G  V +VG  G+GK+SL  AL   L    GR+   G    S+G          IPQ     + SL+ N+  ++   + +  + IE   L E +   PAG +    E G N+S GQ+Q + LARA+ +   + +LD+  +A+D
Sbjct: 1286 VAVERIKEYVEVPTEAPWYNNAARPRSGWPDSGRVEFKNYSVRYRPGLDLVLRDICAAVQPGEKVGIVGRTGAGKSSLTLALFRILEPAGGRIEIDGVDIASLGLHDLRSKLTIIPQDPVLFSGSLRYNLDPAEEHSDAEVWKSIELAHLKEFVAAQPAGLEFVCSEGGENMSVGQRQLVCLARALLRKTKILVLDEATAAID 1488
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. TrEMBL
Match: A0A1I8HV06 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 869.766 bits (2246), Expect = 0.000e+0
Identity = 459/914 (50.22%), Postives = 628/914 (68.71%), Query Frame = 2 
Query:   26 MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYS--RYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTD--SEQINNFQQDFDETQPLLSLIPDDKTIPI-------NRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVS----PPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYL 2722
            +G  ++ SLC   S DW  W D +  NT DPD+TLCFQYT+L+W+P +FL      ++  L    S   R    FN+ K  L+  ++   +++F   ++++ S L  P  +Y+ PIL  +  +L++++    Y+KG+HSSG+LF +WLL+LL SI ++ S  RY  ++  + D FR VT +       V F+   F D          +  ++ +  DET+ LL     +K  P        N  PCPE   SFLS+++F WLTG++I+GY++ LT  DL+AL + DTC  IV  ++  W +E  +  ++    + +  N  TSN  P+     +   +  ++  +  +     PSFLR L    G+PY +AG++K+AYDL+ FAQPQ+L L I FI N + Y W G+ LA+ LFL+++ ++ IFQQYYHG Y TGMR RTAVI  +YRKAL+LSS++RK  TVGEIVNLMSVD+QKLQD P+FLH LW API I +A+YFLW +LGPSVLAG+ +M+ LIP+NGII S+++KLQ  QMK KD RIK+MNE+L+GIK+LKLYAWE  F++ ++  R+ E ++L +A YLNA SA+TWFCAPFLVAL TF  + LSS  ++L ANKAFVSL+LFNI++FP+S+LPG I Y + + VS+ RI  FL  DE+D + V+ S       E PV++  G F WG  E  VL ++N+++P G LVA+VG+VG+GKTSL+SAL+GEL K SG V   G++GY+PQQAWC+NA+L+DNI F K      + RVI ACAL  D+K+LP G +TEIGEKGINLSGGQKQRISLARAVY D  +Y LDDPLSAVDSHVGKHIF+QV+GPSGLLS+KTR+LVTHG+++LPK+D I V+KDG+VSE GT++ELL++NG FAEFI+ YL
Sbjct:   13 LGAIYWESLCGSASLDWAFWSDDLTVNTNDPDLTLCFQYTMLHWLPAVFLLCVSAFHLWDLRRMQSKPGRGVSLFNLAKCVLLLPMMLLMVMDFFRAVTDASSGLVTPAVMYVYPILMLLVLLLVLFITYYEYRKGVHSSGLLFLFWLLELLCSIVILRSKIRYESMQLPNTDGFRLVTWSTFVAFAAVQFVAQLFVDRGALAQHGGSRGRSYNETTDETRSLLQRNEPEKMRPYMKRFVKHNLEPCPELSSSFLSQISFYWLTGMIIRGYKRALTGDDLWALLDRDTCGYIVPLLQKFWKQEQAKAGKSH---QFKYTNQMTSNGLPVAGGRPDGYQN-AEHVASRPDTATYKPSFLRVLGKVFGWPYFIAGIWKLAYDLINFAQPQLLSLLILFIQNGDPYEWRGYFLAVALFLVALFKTFIFQQYYHGTYTTGMRLRTAVIAAVYRKALRLSSSARKNKTVGEIVNLMSVDAQKLQDAPAFLHQLWGAPIIIALALYFLWLQLGPSVLAGLFVMVLLIPVNGIIASRIRKLQISQMKWKDQRIKVMNEVLNGIKVLKLYAWEAFFDKGVREKRDQELKLLLAAAYLNAASAITWFCAPFLVALATFAVYVLSSPENILDANKAFVSLTLFNIMNFPLSILPGAITYLVTSLVSVGRITSFLNADEVDPDAVDTSGHANDSHEFPVQVHKGDFKWGPDEPLVLKDVNLKIPNGKLVAIVGSVGAGKTSLVSALLGELVKTSGSVSVTGTVGYVPQQAWCQNATLRDNITFGKAFQKTTFERVISACALKPDIKILPGGLETEIGEKGINLSGGQKQRISLARAVYSDTDLYFLDDPLSAVDSHVGKHIFEQVLGPSGLLSNKTRLLVTHGISFLPKMDLIVVLKDGSVSEVGTYSELLQHNGGFAEFIQQYL 922

HSP 2 Score: 682.174 bits (1759), Expect = 0.000e+0
Identity = 330/531 (62.15%), Postives = 420/531 (79.10%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYL-FSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCT 4591
            +E G VK SVF SY+RS  +  F+F+V+ +YAL++ C VG N++LS W++  + NGTQ+   +   LG+YG++G GQA+F+L++N  +A GT+ ASK LH+ +L NI++ P SFFD TP+GRI+NR GKDIDTVDVSIP T+RIWLMT  GV+G+I +I I++  F+L  +PL  +YY AQRFY+ TSRQLKRIDS++RSPIYSHFQE+IVGAS IRA+    DF+ K D + D NQMAWYP+IVS RWLQ  LE IGN VIL + V AV +R +I +G AGL++SYALQ+T  LNY+VRMT DLE++ VAVERIKEY E+ +EAPW    ++    WPDSGRVEF NYSVRYRPGLDLVLR++   V  GEK+GIVGRTGAGKSSL LALFR++EPA G I ID  DI  LGLHDLRSK+TIIPQDP+LFSG++R NLDP  +HSD E+W  +E+++LK F+A    GL+++ SEGGEN+SVGQ+QLVCLARALL+K+K+LVLDEATAA+DLETDDLIQ +IRR+FK C+
Sbjct:  978 SETGSVKLSVFKSYVRSFGFGNFAFSVL-TYALFIACQVGQNLWLSEWSQDEAINGTQDTALRDLRLGVYGAIGGGQAIFVLLQNIGIALGTYWASKVLHDDILDNIMKTPLSFFDITPIGRIINRFGKDIDTVDVSIPLTLRIWLMTFGGVVGTIIIIGITTKEFILLFIPLLVLYYFAQRFYVCTSRQLKRIDSVRRSPIYSHFQETIVGASCIRAFGKQQDFVDKSDYLVDWNQMAWYPSIVSNRWLQISLEGIGNFVILFTAVFAVASRYSINAGLAGLAVSYALQVTSSLNYVVRMTCDLETYIVAVERIKEYVEVPTEAPWYNNAARPRPGWPDSGRVEFKNYSVRYRPGLDLVLRDICAAVQPGEKVGIVGRTGAGKSSLTLALFRILEPAGGRIEIDGVDIASLGLHDLRSKLTIIPQDPVLFSGSLRYNLDPAEEHSDAEVWKSIELAHLKEFVAAQPAGLEFVCSEGGENMSVGQRQLVCLARALLRKTKILVLDEATAAIDLETDDLIQQTIRREFKACS 1507

HSP 3 Score: 79.337 bits (194), Expect = 7.825e-11
Identity = 70/281 (24.91%), Postives = 121/281 (43.06%), Query Frame = 2 
Query: 3869 ITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLAN 4702
            + G + Y+V       +  V+V RI  +   +   P  ++ S  H++      V+      ++ P   LVL+++N+ +  G+ + IVG  GAGK+SL  AL   +    G++ +                +  +PQ     + T+R N+             V+    LK  I     GL+  + E G NLS GQKQ + LARA+   + +  LD+  +AVD      I   +          T L + H ++ +   D ++VL+ G V E+ +   LL +
Sbjct:  651 LPGAITYLV-------TSLVSVGRITSFLNADEVDPDAVDTS-GHANDSHEFPVQVHKGDFKWGPDEPLVLKDVNLKIPNGKLVAIVGSVGAGKTSLVSALLGELVKTSGSVSVTG-------------TVGYVPQQAWCQNATLRDNITFGKAFQKTTFERVISACALKPDIKILPGGLETEIGEKGINLSGGQKQRISLARAVYSDTDLYFLDDPLSAVDSHVGKHIFEQVLGPSGLLSNKTRLLVTHGISFLPKMDLIVVLKDGSVSEVGTYSELLQH 910

HSP 4 Score: 65.855 bits (159), Expect = 1.239e-6
Identity = 59/203 (29.06%), Postives = 95/203 (46.80%), Query Frame = 2 
Query: 1955 VSLKRINKFL-VGDELDTENVEVSP----PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG----SIGY---------IPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVD 2509
            V+++RI +++ V  E    N    P    PD   V+  + +  +      VL +I   V  G  V +VG  G+GK+SL  AL   L    GR+   G    S+G          IPQ     + SL+ N+  ++   + +  + IE   L E +   PAG +    E G N+S GQ+Q + LARA+ +   + +LD+  +A+D
Sbjct: 1286 VAVERIKEYVEVPTEAPWYNNAARPRPGWPDSGRVEFKNYSVRYRPGLDLVLRDICAAVQPGEKVGIVGRTGAGKSSLTLALFRILEPAGGRIEIDGVDIASLGLHDLRSKLTIIPQDPVLFSGSLRYNLDPAEEHSDAEVWKSIELAHLKEFVAAQPAGLEFVCSEGGENMSVGQRQLVCLARALLRKTKILVLDEATAAID 1488
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. TrEMBL
Match: A0A452I2X5 (ATP binding cassette subfamily C member 1 OS=Gopherus agassizii OX=38772 GN=ABCC1 PE=4 SV=1)

HSP 1 Score: 788.875 bits (2036), Expect = 0.000e+0
Identity = 412/899 (45.83%), Postives = 585/899 (65.07%), Query Frame = 2 
Query:   50 LCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSR-YRRLKFH-DRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRE-----NQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTEN-VEVSPPD-EKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            LCS+  ++   W   + W+T++PD T CFQ TIL W+P ++LW+   IY   L +     Y      N  K+ L   +      +   +  E   N++ PP   + P +  I+ +L  +L +    KG+ SSGV+  +W   LL +  +  S+    LK   + D+FR VT    F+LV +  IL+CF                    E  PL S   +D        PCPE+  SFLSK+TF W+TGL+I+GYR+PL  KDL++L ++DT + +V  +   W +E      Q +K     KK  K    +SN     +EE E  I           Q+   PS L+ L+ T G  ++++ +FK  +DL+ F+ P+IL L I F+++ +   W G+L    LF  + ++++I  QY+H C+VTGMR +TAVIG +YRKAL +++++RK +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+Y LWQ LGPSVLAGVA+MI L+P+N ++  K K  Q   MK KDNRIKLMNEIL+GIK+LKLYAWE +F++ +  IR +E ++L+ + YL AVS  TW CAPFLVAL TF  + L   ++VL A KAFVSL+LFNIL FP+++LP VI   +QA VSLKR+  FL  +ELD ++ +  S  D E  + + + TFSW + + P L +IN  VPEGSL+A+VG VG GK+SL+SAL+GE+ K  G V  +GS+ Y+PQQAW +NASL+DNI+F + +   +Y RVIEACAL  D+++LP+GD+TEIGEKG+NLSGGQKQR+SLARAVY +  VYL DDPLSAVD+HVGKHIFD+VIGP G+L +KTR+LVTHG++YLP +D+I VM DG +SE G++ ELLK +G+FAEF+RTY
Sbjct:    6 LCSEGGSE-PFWDWNLTWHTENPDFTKCFQNTILVWVPCIYLWVCFPIYFLYLRHHDRG-YIQMSHLNKAKTALGLLLWIICWADLFYSFWERSQNVFRPPVFVISPTVLGITMLLATFLIQFERMKGVQSSGVMLIFWFTALLCATIIFRSKILHALKLGPEVDVFRYVTFYSYFILVLIQLILSCFP-------------------ERPPLFSETINDSN------PCPESSASFLSKITFWWITGLMIQGYRRPLEAKDLWSLNKDDTSEEVVKGLAKYWEKECADTNKQAIKMVYSPKKQMK----SSNSNGDVTEEVEALI-------VKPSQRNSGPSLLKVLYKTFGPYFLMSFLFKACHDLMMFSGPEILKLLINFVNDKDAPNWQGYLYTGLLFACACLQTLILHQYFHICFVTGMRLKTAVIGAVYRKALVITNSARKTSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWQNLGPSVLAGVAVMILLVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKEKVLGIRQEELKVLKKSAYLAAVSTFTWVCAPFLVALSTFAVYVLVDKNNVLDAQKAFVSLALFNILRFPLNILPMVISSMVQASVSLKRLKLFLSHEELDPDSIIRGSIKDAEGSIIVKNATFSWSRNDPPSLNDINFTVPEGSLIAIVGQVGCGKSSLLSALLGEMDKREGYVAVKGSVAYVPQQAWIQNASLKDNIIFGREMKESQYKRVIEACALLPDIEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNTDVYLFDDPLSAVDAHVGKHIFDKVIGPKGILKNKTRVLVTHGVSYLPLMDRIIVMTDGEISEMGSYQELLKQDGAFAEFLRTY 866

HSP 2 Score: 634.795 bits (1636), Expect = 0.000e+0
Identity = 314/584 (53.77%), Postives = 432/584 (73.97%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGA---NMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A+ G VK  V+  Y++S   L SF  +F   L+MC  + A   N +LS WT+    NGTQ        LG+YG+LG  Q + +   + A++ G   AS+ LH  LL N+LR+P SFF+ TP G ++NR  K+IDT+D  IP  I++++ +   VIG+  VI +++P   + + PL  +Y+  QRFY+ TSRQLKR++S+ RSP+YSHF E+++G S IRA++    F  + D+  DENQ A++P+IV+ RWL   LE +GN ++L + + AV+ R ++  G  GLS+SY+LQ+T  LN++VRMTS+LE++ VAVER++EY+E+E EAPW IE++   ++WP  G+VEF  Y +RYR  LDLVL+N+N+ ++ GEK+GIVGRTGAGKSSL L LFR+ E AEG IIID  ++ K+GLHDLR KITIIPQDP+LFSG++RMNLDPF+++SD E+W+ LE+++LK+F++   + L +  SEGGENLSVGQ+QLVCLARALL+KSK+LVLDEATAAVDLETDDLIQS+IR QF+ CTVLTIAHRLNTIMDY+RV+VL++G + E DSP NLL  +K IF+SMA D+GL
Sbjct:  946 AKTGRVKAIVYWEYMKSIGLLISFLSIF---LFMCNHIAALASNYWLSLWTDDPVINGTQQ--HTHVRLGVYGALGMSQGIAVFGYSMAVSIGGIFASRHLHIDLLHNVLRSPMSFFERTPSGNLVNRFSKEIDTIDSVIPQIIKMFMGSLFNVIGACIVILLATPIAAIVIPPLGLVYFFVQRFYVATSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQTRFKLQSDLKVDENQKAYFPSIVANRWLAIRLECVGNCIVLFAALFAVIARHSLSPGLVGLSVSYSLQVTTYLNWLVRMTSELETNIVAVERVQEYSEMEKEAPWCIEQTAPPNNWPHEGQVEFRGYGLRYREDLDLVLKNINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNVAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFDKYSDEEIWTSLELAHLKNFVSSLPDKLNHECSEGGENLSVGQRQLVCLARALLRKSKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYERVIVLDKGEIVECDSPANLL-QKKGIFYSMAKDSGL 1523

HSP 3 Score: 78.5666 bits (192), Expect = 1.491e-10
Identity = 68/278 (24.46%), Postives = 122/278 (43.88%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            LN +  + S +   +V+++R+K +   E   P +I            G +   N +  +       L ++N  V  G  + IVG+ G GKSSL  AL   ++  EG + +             +  +  +PQ   + + +++ N+    +  + +   V+E   L   I     G +  + E G NLS GQKQ V LARA+   + V + D+  +AVD      I   +   +   K  T + + H ++ +   DR++V+  G + E+ S Q LL  +
Sbjct:  595 LNILPMVISSMVQASVSLKRLKLFLSHEELDPDSIIRGSIKDA---EGSIIVKNATFSWSRNDPPSLNDINFTVPEGSLIAIVGQVGCGKSSLLSALLGEMDKREGYVAV-------------KGSVAYVPQQAWIQNASLKDNIIFGREMKESQYKRVIEACALLPDIEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNTDVYLFDDPLSAVDAHVGKHIFDKVIGPKGILKNKTRVLVTHGVSYLPLMDRIIVMTDGEISEMGSYQELLKQD 856

HSP 4 Score: 67.0106 bits (162), Expect = 4.474e-7
Identity = 86/380 (22.63%), Postives = 144/380 (37.89%), Query Frame = 2 
Query: 1640 NEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWF---------CAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPG-----VIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-------------SIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            NE L G+ +++ +  +  F+    +++ DE        Y  ++ A  W          C     AL  F      S S  L       SL +   L++ + M        V V  +Q Y  +++   + +       N     P E  V+       + +    VL NIN+ +  G  V +VG  G+GK+SL   L        G ++  G              I  IPQ     + SL+ N+       + +    +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +   +++ V+  G + E  +   LL+  G F
Sbjct: 1149 NETLLGVSVIRAFEEQTRFKLQ-SDLKVDE----NQKAYFPSIVANRWLAIRLECVGNCIVLFAAL--FAVIARHSLSPGLVGLSVSYSLQVTTYLNWLVRMTSELETNIVAVERVQEYSEMEKEAPWCIEQTAPPNNW----PHEGQVEFRGYGLRYREDLDLVLKNINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNVAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFDKYSDEEIWTSLELAHLKNFVSSLPDKLNHECSEGGENLSVGQRQLVCLARALLRKSKILVLDEATAAVDLETDDLIQSTI---RTQFEDCTVLTIAHRLNTIMDYERVIVLDKGEIVECDSPANLLQKKGIF 1514
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Cavefish
Match: abcc3 (ATP binding cassette subfamily C member 3 [Source:NCBI gene;Acc:103023748])

HSP 1 Score: 766.533 bits (1978), Expect = 0.000e+0
Identity = 400/896 (44.64%), Postives = 559/896 (62.39%), Query Frame = 2 
Query:   50 LCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPIL-WNKASFIYR---NRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRL-KFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSP-PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            LC  K      W   +  +T+ PD+  CFQ ++L WIP  +LW+   +Y+  L  N   +I     NR K      T+  FIL+             I     PP  ++ P++  ++ +L  ++ +    +G+ SSGVLF +W+L +L +I    S+     K  + D  R  T    F L+ V  IL CF                   +E  PL S +  D        PCPE+   FLS++TF W T + IKGY+ PL  KDL++L + D+ + +V  +  +W  E  + +  +     +  NG     K                   + ++    PSFLR+L    G  +++   FK+  DL+TF  PQ+L + I F        W GF LA  +F  ++++++I  Q++  C+VTGMR RTA+IG IYRK+L +++ +++ +TVGE+VNLMSVD+Q+  D+ +FL++LW+AP+ I++A++FLWQ LGPSVLAGVA+M+ LIP N +I  K +  Q +QM+ KD RIKLMNEIL+GIK+LKLYAWE SF++ +  IR  E  +LR   YL+A+S + W  APFLVAL TF  +     ++VL A+KAFVSLSLFNIL FP++MLP VI   +QA VSLKRI  FL  DELD +NV+  P P +  V +V+G FSW K + P L +IN+ VP+GSL+AVVG VG GK+SL++AL+GE+ K+ G +  RGS+ Y+PQQAW +NA+L+DNILF +P +  KY  V+EACALT DL+VLP GD TEIGEKGINLSGGQ+QR+SLARA+Y +  VYL+DDPLSAVD+HV KHIFD VIGP G L  KTRILVTHG+++LP+VD I V+ +G VSE G++ +LLK NG+FAEF+R Y
Sbjct:    4 LCGPKP----FWKPNLTLSTEIPDLPECFQLSVLAWIPCFYLWLVSPLYLFYLKRNNRGYIMMSILNRVK------TVFGFILWIVCWTDLFASFHEIKEKDVPPIYFITPLIVGMTMLLATFIIQFERLRGVQSSGVLFIFWMLSVLCAIVPFRSKILHANKGENVDKLRFTTFYMYFGLILVELILCCF-------------------NEKPPLFSSVVTDPN------PCPESTAGFLSRMTFWWFTSMAIKGYKSPLETKDLWSLNKQDSSELVVPKLLREWEGEKSKAQSIE-----QDVNGQAVYSKAGAETNHVEVNPEEVEVLLSSKKDTPQPSFLRSLLKAFGPYFLIGSAFKLLQDLITFINPQLLRMLIEFTKETGVPSWWGFALAFMMFGCALLQTLILHQHFQYCFVTGMRLRTAIIGAIYRKSLVITNEAKRSSTVGEVVNLMSVDAQRFMDLTTFLNMLWSAPLQIILALFFLWQTLGPSVLAGVAVMVLLIPFNAVIAMKTRAYQVEQMQYKDARIKLMNEILNGIKVLKLYAWEVSFKEKVLQIRQKELNVLRKTAYLSALSTMAWTSAPFLVALTTFAVYVSVDKNNVLDADKAFVSLSLFNILRFPLNMLPQVISSLVQASVSLKRIQAFLSHDELDPDNVDKKPAPSDHAVTVVNGKFSWAKKDPPALQHINVMVPQGSLLAVVGHVGCGKSSLVAALLGEMEKLEGHISIRGSVAYVPQQAWIQNATLRDNILFGRPYVEQKYRCVLEACALTPDLEVLPGGDLTEIGEKGINLSGGQRQRVSLARALYSEADVYLMDDPLSAVDAHVAKHIFDHVIGPEGALRGKTRILVTHGISFLPQVDNILVLVEGMVSEMGSYQDLLKQNGAFAEFLRNY 859

HSP 2 Score: 650.588 bits (1677), Expect = 0.000e+0
Identity = 315/582 (54.12%), Postives = 419/582 (71.99%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            AE G VKF V+  Y ++   + S  + F YA     ++GAN++LS WT   S +     +     +G+Y SLG  Q + ++  +F LA G   A++ LH  LL N    P +FFDTTPLGRI+NR  KDI  +D ++P+TI ++L T    + ++ VI  S+P F + +VPL  +Y+  QRFY+ TSRQLKR++S+ RSPIYSHF E+I G S IRAY  +  F+   D+  DENQ ++YP IVS RWL   +E IGN ++L + V AV+ +  +  G  GLS+SYALQ+T  LN+MVRMTSDLES+ VAVER+KEY+E   EAPW +E+ +  +DWP  G VEF +YSVRYR GLDLVLRN+++ V  GEK+GIVGRTGAGKSS+ L LFRL+E A G I ID   I ++GLHDLRSK+TIIPQ+P+LFSGT+RMNLDPF ++SD ++W+ L +S+L  F++     L    SEGGENLSVGQ+QL+CLARALL+K+++L+LDEATAA+DLETDDLIQS+IR QF+ CTV TIAHRLNTIMDY R++VL++G++ E D+P NL+A +K IF+SMA DAGLA
Sbjct:  956 AETGRVKFKVYWEYAKAVGPILSLFICFLYASQSAAAIGANIWLSQWT-NDSRDSVTAQEKVHMRVGVYASLGITQGILVMFSSFTLAMGKIQAARKLHQGLLDNKFHTPQAFFDTTPLGRIINRFSKDIYVIDEALPSTILMFLGTFFASVATMIVIVSSTPIFAVVIVPLALVYFFVQRFYVATSRQLKRLESVSRSPIYSHFSETITGTSVIRAYGRNSAFVLMSDMKVDENQKSYYPGIVSNRWLGIRIEFIGNCIVLFAAVFAVLEKENLSPGLVGLSVSYALQVTMSLNWMVRMTSDLESNIVAVERVKEYSETPPEAPWEVEDKKPPTDWPSEGNVEFADYSVRYREGLDLVLRNISLRVKGGEKIGIVGRTGAGKSSMTLCLFRLLEAAGGEITIDGVKIKEIGLHDLRSKLTIIPQEPVLFSGTLRMNLDPFEKYSDDDMWNALTLSHLHKFVSNQPAKLALECSEGGENLSVGQRQLICLARALLRKTRILILDEATAAIDLETDDLIQSTIRTQFEDCTVFTIAHRLNTIMDYTRILVLDKGQIAEFDTPVNLIA-QKGIFYSMAKDAGLA 1535

HSP 3 Score: 98.5969 bits (244), Expect = 4.755e-20
Identity = 105/417 (25.18%), Postives = 182/417 (43.65%), Query Frame = 2 
Query: 3497 LLALVPLTAMYYMAQRFYIYTSRQLKR---------IDSIKRSPIYS---HFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAW--YPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            ++ L+P  A+  M  R Y     Q K          ++ IK   +Y+    F+E ++    IR  ++  + ++K   ++  + MAW   P +V+      Y+    N V+                 +  LS+   L+    LN + ++ S L   +V+++RI+ +   +   P N+++  A SD      V  VN    +       L+++N++V  G  L +VG  G GKSSL  AL   +E  EG I I             R  +  +PQ   + + T+R N+     + + +   VLE   L   +     G    + E G NLS GQ+Q V LARAL  ++ V ++D+  +AVD      I   +       +  T + + H ++ +   D ++VL +G V E+ S Q+LL
Sbjct:  466 MVLLIPFNAVIAMKTRAYQVEQMQYKDARIKLMNEILNGIKVLKLYAWEVSFKEKVL---QIRQKEL--NVLRKTAYLSALSTMAWTSAPFLVALTTFAVYVSVDKNNVL------------DADKAFVSLSLFNILRFP--LNMLPQVISSLVQASVSLKRIQAFLSHDELDPDNVDKKPAPSD----HAVTVVNGKFSWAKKDPPALQHINVMVPQGSLLAVVGHVGCGKSSLVAALLGEMEKLEGHISI-------------RGSVAYVPQQAWIQNATLRDNILFGRPYVEQKYRCVLEACALTPDLEVLPGGDLTEIGEKGINLSGGQRQRVSLARALYSEADVYLMDDPLSAVDAHVAKHIFDHVIGPEGALRGKTRILVTHGISFLPQVDNILVLVEGMVSEMGSYQDLL 846

HSP 4 Score: 68.9366 bits (167), Expect = 4.750e-11
Identity = 61/240 (25.42%), Postives = 100/240 (41.67%), Query Frame = 2 
Query: 2027 PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVL---PAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            P E  V+  D +  + +    VL NI++ V  G  + +VG  G+GK+S+   L   L    G +               R  +  IPQ+    + +L+ N+    P   +  + +  A  L+   K +   PA    E  E G NLS GQ+Q I LARA+ +   + +LD+  +A+D      I   +          T   + H L  +    +I V+  G ++E  T   L+   G F
Sbjct: 1292 PSEGNVEFADYSVRYREGLDLVLRNISLRVKGGEKIGIVGRTGAGKSSMTLCLFRLLEAAGGEITIDGVKIKEIGLHDLRSKLTIIPQEPVLFSGTLRMNL---DPFEKYSDDDMWNALTLSHLHKFVSNQPAKLALECSEGGENLSVGQRQLICLARALLRKTRILILDEATAAIDLETDDLIQSTI---RTQFEDCTVFTIAHRLNTIMDYTRILVLDKGQIAEFDTPVNLIAQKGIF 1525
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Cavefish
Match: abcc3 (ATP binding cassette subfamily C member 3 [Source:NCBI gene;Acc:103023748])

HSP 1 Score: 765.763 bits (1976), Expect = 0.000e+0
Identity = 400/896 (44.64%), Postives = 559/896 (62.39%), Query Frame = 2 
Query:   50 LCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPIL-WNKASFIYR---NRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRL-KFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSP-PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            LC  K      W   +  +T+ PD+  CFQ ++L WIP  +LW+   +Y+  L  N   +I     NR K      T+  FIL+             I     PP  ++ P++  ++ +L  ++ +    +G+ SSGVLF +W+L +L +I    S+     K  + D  R  T    F L+ V  IL CF                   +E  PL S +  D        PCPE+   FLS++TF W T + IKGY+ PL  KDL++L + D+ + +V  +  +W  E  + +  +     +  NG     K                   + ++    PSFLR+L    G  +++   FK+  DL+TF  PQ+L + I F        W GF LA  +F  ++++++I  Q++  C+VTGMR RTA+IG IYRK+L +++ +++ +TVGE+VNLMSVD+Q+  D+ +FL++LW+AP+ I++A++FLWQ LGPSVLAGVA+M+ LIP N +I  K +  Q +QM+ KD RIKLMNEIL+GIK+LKLYAWE SF++ +  IR  E  +LR   YL+A+S + W  APFLVAL TF  +     ++VL A+KAFVSLSLFNIL FP++MLP VI   +QA VSLKRI  FL  DELD +NV+  P P +  V +V+G FSW K + P L +IN+ VP+GSL+AVVG VG GK+SL++AL+GE+ K+ G +  RGS+ Y+PQQAW +NA+L+DNILF +P +  KY  V+EACALT DL+VLP GD TEIGEKGINLSGGQ+QR+SLARA+Y +  VYL+DDPLSAVD+HV KHIFD VIGP G L  KTRILVTHG+++LP+VD I V+ +G VSE G++ +LLK NG+FAEF+R Y
Sbjct:    4 LCGPKP----FWKPNLTLSTEIPDLPECFQLSVLAWIPCFYLWLVSPLYLFYLKRNNRGYIMMSILNRVK------TVFGFILWIVCWTDLFASFHEIKEKDVPPIYFITPLIVGMTMLLATFIIQFERLRGVQSSGVLFIFWMLSVLCAIVPFRSKILHANKGENVDKLRFTTFYMYFGLILVELILCCF-------------------NEKPPLFSSVVTDPN------PCPESTAGFLSRMTFWWFTSMAIKGYKSPLETKDLWSLNKQDSSELVVPKLLREWEGEKSKAQSIE-----QDVNGQAVYSKAGAETNHVEVNPEEVEVLLSSKKDTPQPSFLRSLLKAFGPYFLIGSAFKLLQDLITFINPQLLRMLIEFTKETGVPSWWGFALAFMMFGCALLQTLILHQHFQYCFVTGMRLRTAIIGAIYRKSLVITNEAKRSSTVGEVVNLMSVDAQRFMDLTTFLNMLWSAPLQIILALFFLWQTLGPSVLAGVAVMVLLIPFNAVIAMKTRAYQVEQMQYKDARIKLMNEILNGIKVLKLYAWEVSFKEKVLQIRQKELNVLRKTAYLSALSTMAWTSAPFLVALTTFAVYVSVDKNNVLDADKAFVSLSLFNILRFPLNMLPQVISSLVQASVSLKRIQAFLSHDELDPDNVDKKPAPSDHAVTVVNGKFSWAKKDPPALQHINVMVPQGSLLAVVGHVGCGKSSLVAALLGEMEKLEGHISIRGSVAYVPQQAWIQNATLRDNILFGRPYVEQKYRCVLEACALTPDLEVLPGGDLTEIGEKGINLSGGQRQRVSLARALYSEADVYLMDDPLSAVDAHVAKHIFDHVIGPEGALRGKTRILVTHGISFLPQVDNILVLVEGMVSEMGSYQDLLKQNGAFAEFLRNY 859

HSP 2 Score: 643.269 bits (1658), Expect = 0.000e+0
Identity = 314/583 (53.86%), Postives = 413/583 (70.84%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENF-ALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            AE G VKF V+  Y ++   + S  + F YA     ++GAN++LS WT   S +     +     +G+Y SLG  Q + IL       AY    A+ + H  +L  +LRAP +FF+ TP GR+LNR  KD+DT+D  IP  I IW+ T    +  + V S  +P FL+ +VPL   Y+  QRFY+ TSRQLKR++S+ RSPIYSHF E+I G S IRAY  +  F+   D+  DENQ ++YP IVS RWL   +E IGN ++L + V AV+ +  +  G  GLS+SYALQ+T  LN+MVRMTSDLES+ VAVER+KEY+E   EAPW +E+ +  +DWP  G VEF +YSVRYR GLDLVLRN+++ V  GEK+GIVGRTGAGKSS+ L LFRL+E A G I ID   I ++GLHDLRSK+TIIPQ+P+LFSGT+RMNLDPF ++SD ++W+ L +S+L  F++     L    SEGGENLSVGQ+QL+CLARALL+K+++L+LDEATAA+DLETDDLIQS+IR QF+ CTV TIAHRLNTIMDY R++VL++G++ E D+P NL+A +K IF+SMA DAGLA
Sbjct:  956 AETGRVKFKVYWEYAKAVGPILSLFICFLYASQSAAAIGANIWLSQWT-NDSRDSVTAQEKVHMRVGVYASLGITQGVLILANCLLCRAYSMLKAAHATHLTMLHAVLRAPQAFFEATPSGRLLNRFSKDVDTIDSLIPDNIDIWMRTFWYTVNVLLVCSALTPMFLIVIVPLMMFYWWVQRFYVATSRQLKRLESVSRSPIYSHFSETITGTSVIRAYGRNSAFVLMSDMKVDENQKSYYPGIVSNRWLGIRIEFIGNCIVLFAAVFAVLEKENLSPGLVGLSVSYALQVTMSLNWMVRMTSDLESNIVAVERVKEYSETPPEAPWEVEDKKPPTDWPSEGNVEFADYSVRYREGLDLVLRNISLRVKGGEKIGIVGRTGAGKSSMTLCLFRLLEAAGGEITIDGVKIKEIGLHDLRSKLTIIPQEPVLFSGTLRMNLDPFEKYSDDDMWNALTLSHLHKFVSNQPAKLALECSEGGENLSVGQRQLICLARALLRKTRILILDEATAAIDLETDDLIQSTIRTQFEDCTVFTIAHRLNTIMDYTRILVLDKGQIAEFDTPVNLIA-QKGIFYSMAKDAGLA 1536

HSP 3 Score: 98.5969 bits (244), Expect = 4.837e-20
Identity = 105/417 (25.18%), Postives = 182/417 (43.65%), Query Frame = 2 
Query: 3497 LLALVPLTAMYYMAQRFYIYTSRQLKR---------IDSIKRSPIYS---HFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAW--YPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            ++ L+P  A+  M  R Y     Q K          ++ IK   +Y+    F+E ++    IR  ++  + ++K   ++  + MAW   P +V+      Y+    N V+                 +  LS+   L+    LN + ++ S L   +V+++RI+ +   +   P N+++  A SD      V  VN    +       L+++N++V  G  L +VG  G GKSSL  AL   +E  EG I I             R  +  +PQ   + + T+R N+     + + +   VLE   L   +     G    + E G NLS GQ+Q V LARAL  ++ V ++D+  +AVD      I   +       +  T + + H ++ +   D ++VL +G V E+ S Q+LL
Sbjct:  466 MVLLIPFNAVIAMKTRAYQVEQMQYKDARIKLMNEILNGIKVLKLYAWEVSFKEKVL---QIRQKEL--NVLRKTAYLSALSTMAWTSAPFLVALTTFAVYVSVDKNNVL------------DADKAFVSLSLFNILRFP--LNMLPQVISSLVQASVSLKRIQAFLSHDELDPDNVDKKPAPSD----HAVTVVNGKFSWAKKDPPALQHINVMVPQGSLLAVVGHVGCGKSSLVAALLGEMEKLEGHISI-------------RGSVAYVPQQAWIQNATLRDNILFGRPYVEQKYRCVLEACALTPDLEVLPGGDLTEIGEKGINLSGGQRQRVSLARALYSEADVYLMDDPLSAVDAHVAKHIFDHVIGPEGALRGKTRILVTHGISFLPQVDNILVLVEGMVSEMGSYQDLL 846

HSP 4 Score: 69.3218 bits (168), Expect = 4.186e-11
Identity = 61/240 (25.42%), Postives = 100/240 (41.67%), Query Frame = 2 
Query: 2027 PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVL---PAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            P E  V+  D +  + +    VL NI++ V  G  + +VG  G+GK+S+   L   L    G +               R  +  IPQ+    + +L+ N+    P   +  + +  A  L+   K +   PA    E  E G NLS GQ+Q I LARA+ +   + +LD+  +A+D      I   +          T   + H L  +    +I V+  G ++E  T   L+   G F
Sbjct: 1293 PSEGNVEFADYSVRYREGLDLVLRNISLRVKGGEKIGIVGRTGAGKSSMTLCLFRLLEAAGGEITIDGVKIKEIGLHDLRSKLTIIPQEPVLFSGTLRMNL---DPFEKYSDDDMWNALTLSHLHKFVSNQPAKLALECSEGGENLSVGQRQLICLARALLRKTRILILDEATAAIDLETDDLIQSTI---RTQFEDCTVFTIAHRLNTIMDYTRILVLDKGQIAEFDTPVNLIAQKGIF 1526
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Cavefish
Match: abcc1 (ATP binding cassette subfamily C member 1 [Source:NCBI gene;Acc:103043969])

HSP 1 Score: 746.117 bits (1925), Expect = 0.000e+0
Identity = 393/916 (42.90%), Postives = 572/916 (62.45%), Query Frame = 2 
Query:   26 MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIY---RNRGKFNIFKSTLIAFILFFHLLNFC-----ATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQT--------KFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSP--PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            MG  HF S+  D S+ +  W     W+T +PD+T CFQ T+L  +P  +LW+    Y         F+Y    +RG   +        +  F L   C      +  E    +   P   + P +  I+ +L   L +    KG+ SSG++  +WL+  + +     S+          + + V    E + VF       ++   ++     I+       +  PL S    D        PCPE   SFLS+++F W+TGL+++GY++PL  KDL++L   D   T+V  +  +W+ E  + K+T        K     EK++G     +P+    EE+EI  ++    +       PS   AL  T G  ++++ ++K+ +D+L F  P+IL L I F+++ +   WHG+     LF+ +  +++I Q+Y+H C+VTGMR RTA++G +YRKAL +++ +R+ +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+YFLWQ LGPSVLAGVA+M+ ++P+N +I  K K  Q  QMK KDNRIKLMNE+L+GIK+LKLYAWE +F+  +  IR  E R+L+ A YL A+S  TW CAPFLVAL TF  + L    +VL A KAFVSL+LFNIL FP++MLP VI   +QA VS+KR+  FL  +ELD  +V+          ++I DG FSW K + P L  IN+ +PEG+LVAVVG VGSGK+SL+SAL+GE++K  G V  +GS+ Y+PQQAW +NA+L++NI+F +      Y +V+EACAL  DL++LP GD TEIGEKG+NLSGGQKQR+SLARAVY DCSVYLLDDPLSAVD+HVGKHIF++VIGP G+L  +TR+LVTHGL++LP+ D I VM DG ++E+G++TELL   G+FA+F+RTY
Sbjct:    1 MGIDHFCSV--DGSDPFWDWNRT--WHTHNPDLTQCFQNTLLVVVPCFYLWLFAPFY---------FLYLKSHDRGYICMTHLNKAKTVTGFLLWIICWADVFYSFWERGHGVASAPVYLVSPTILGITMLLATLLIQYERIKGVQSSGIMLNFWLVATVCATVTFRSK----------ILQAVNEP-ETVNVFR------YSTFYIYYALLLISLILSCLSDQPPLFSQAVKDSN------PCPEAGASFLSRISFWWITGLMVQGYKRPLEEKDLWSLNAEDRSHTVVPQLVRRWDHECSKGKRTDDKTMYSPKRPSMAEKKDG-----RPV----EESEILLIKAPQKSG-----DPSLFLALCRTFGPYFLVSSIYKIIHDVLMFVGPEILRLLIQFVNDSDAPSWHGYFYTALLFVCTCFQTLILQKYFHVCFVTGMRLRTAIVGAVYRKALVITNAARRTSTVGEIVNLMSVDAQRFMDLITYINMIWSAPLQVILALYFLWQNLGPSVLAGVAVMVLMVPVNAVIAMKTKTYQVAQMKSKDNRIKLMNEVLNGIKVLKLYAWELAFKDKVSTIRESELRVLKKAAYLGAISTFTWVCAPFLVALSTFAVYVLVDEHNVLDAQKAFVSLALFNILRFPLNMLPMVISSMVQASVSMKRLRVFLSHEELDENSVDRRAITGSADSIRIGDGAFSWSKEDRPALKRINVRIPEGALVAVVGHVGSGKSSLLSALLGEMHKQEGDVSIKGSVAYVPQQAWIQNATLRENIMFGQEKKESWYQKVLEACALLPDLEILPGGDTTEIGEKGVNLSGGQKQRVSLARAVYCDCSVYLLDDPLSAVDAHVGKHIFEKVIGPQGVLQGRTRVLVTHGLSFLPQADLILVMVDGEITETGSYTELLNRQGAFADFLRTY 866

HSP 2 Score: 610.142 bits (1572), Expect = 0.000e+0
Identity = 293/581 (50.43%), Postives = 422/581 (72.63%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A  G VK +VF  Y+++     SF  +  +  +   S+G+N +LS WT+    NGTQ   S+   LG+YG+LG  Q + +   + +++ G  LAS+ LH  +L N+LR+P SFF+ TP G ++NR  K+ DT+D  IP+ I++++ +   V+GS  VI I++P   + + PL  +Y+  QRFY+ +SRQLKR++S+ RSP+Y+HF E+++G S IRA+     FI + D   D NQ A++P+IV+ RWL   LE +GN ++  + + AV+ R+ +  G  GLSISYALQ+T  LN++VRM+S++E++ VAVER+KEY + E EA W +E+S   + WP +G +E  N+ +RYR  L+L + ++ ++++ GEK+GIVGRTGAGKSSL L LFR+IE A+G I ID  +I  LGLHDLRS+ITIIPQDP+LFSG++RMNLDPF+ +SD ++W  LE+++LK+F++   + L +  SEGGENLS+GQ+QLVCLARALL+K+K+LVLDEATAAVDLETD+LIQS+IR QF+ CTVLTIAHRLNTIMDY RV+VL++G++ E DSP +L+A +K IF+ MA D+GL
Sbjct:  939 ANTGRVKLAVFWEYMKAIGVFLSFISILLFLAHHVSSLGSNYWLSLWTDDPVINGTQ--PSREMRLGVYGALGLSQGIAVFCYSISVSIGGILASRYLHETMLYNVLRSPMSFFERTPSGNLVNRFAKETDTIDSVIPSIIKMFMGSMFNVLGSCAVILIATPLVAIIIPPLGLLYFFVQRFYVASSRQLKRLESVSRSPVYTHFNETLLGTSVIRAFGEQQRFIGESDRRVDHNQKAYFPSIVANRWLAVRLEFVGNCIVTFAALFAVMARANLSPGIMGLSISYALQVTASLNWLVRMSSEVETNIVAVERVKEYEDTEKEAEWKLEQSSVPAGWPTAGHIEVRNFGLRYREDLELAIHDITVIIEGGEKVGIVGRTGAGKSSLTLGLFRIIEAAQGEICIDGVNIANLGLHDLRSRITIIPQDPVLFSGSLRMNLDPFDGYSDEDVWRALELAHLKNFVSGLPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGKMAEFDSPASLIA-KKGIFYKMAKDSGL 1516

HSP 3 Score: 75.485 bits (184), Expect = 4.729e-13
Identity = 74/284 (26.06%), Postives = 126/284 (44.37%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVE--FVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIF 4717
            LN +  + S +   +V+++R++ +   E E   N  + +A +   DS R+     ++S   RP L    + +N+ +  G  + +VG  G+GKSSL  AL   +   EG + I             +  +  +PQ   + + T+R N+    +  +     VLE   L   +     G    + E G NLS GQKQ V LARA+     V +LD+  +AVD      I   +   +   +  T + + H L+ +   D ++V+  G + E  S   LL N +  F
Sbjct:  595 LNMLPMVISSMVQASVSMKRLRVFLSHE-ELDENSVDRRAITGSADSIRIGDGAFSWSKEDRPAL----KRINVRIPEGALVAVVGHVGSGKSSLLSALLGEMHKQEGDVSI-------------KGSVAYVPQQAWIQNATLRENIMFGQEKKESWYQKVLEACALLPDLEILPGGDTTEIGEKGVNLSGGQKQRVSLARAVYCDCSVYLLDDPLSAVDAHVGKHIFEKVIGPQGVLQGRTRVLVTHGLSFLPQADLILVMVDGEITETGSYTELL-NRQGAF 859

HSP 4 Score: 60.4622 bits (145), Expect = 2.004e-8
Identity = 53/213 (24.88%), Postives = 86/213 (40.38%), Query Frame = 2 
Query: 2099 NINMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            +I + +  G  V +VG  G+GK+SL   L   +    G +               R  I  IPQ     + SL+ N+       +    R +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G ++E  +   L+   G F
Sbjct: 1298 DITVIIEGGEKVGIVGRTGAGKSSLTLGLFRIIEAAQGEICIDGVNIANLGLHDLRSRITIIPQDPVLFSGSLRMNLDPFDGYSDEDVWRALELAHLKNFVSGLPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTI---RTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGKMAEFDSPASLIAKKGIF 1507
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Cavefish
Match: abcc1 (ATP binding cassette subfamily C member 1 [Source:NCBI gene;Acc:103043969])

HSP 1 Score: 746.117 bits (1925), Expect = 0.000e+0
Identity = 393/916 (42.90%), Postives = 572/916 (62.45%), Query Frame = 2 
Query:   26 MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIY---RNRGKFNIFKSTLIAFILFFHLLNFC-----ATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQT--------KFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSP--PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            MG  HF S+  D S+ +  W     W+T +PD+T CFQ T+L  +P  +LW+    Y         F+Y    +RG   +        +  F L   C      +  E    +   P   + P +  I+ +L   L +    KG+ SSG++  +WL+  + +     S+          + + V    E + VF       ++   ++     I+       +  PL S    D        PCPE   SFLS+++F W+TGL+++GY++PL  KDL++L   D   T+V  +  +W+ E  + K+T        K     EK++G     +P+    EE+EI  ++    +       PS   AL  T G  ++++ ++K+ +D+L F  P+IL L I F+++ +   WHG+     LF+ +  +++I Q+Y+H C+VTGMR RTA++G +YRKAL +++ +R+ +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+YFLWQ LGPSVLAGVA+M+ ++P+N +I  K K  Q  QMK KDNRIKLMNE+L+GIK+LKLYAWE +F+  +  IR  E R+L+ A YL A+S  TW CAPFLVAL TF  + L    +VL A KAFVSL+LFNIL FP++MLP VI   +QA VS+KR+  FL  +ELD  +V+          ++I DG FSW K + P L  IN+ +PEG+LVAVVG VGSGK+SL+SAL+GE++K  G V  +GS+ Y+PQQAW +NA+L++NI+F +      Y +V+EACAL  DL++LP GD TEIGEKG+NLSGGQKQR+SLARAVY DCSVYLLDDPLSAVD+HVGKHIF++VIGP G+L  +TR+LVTHGL++LP+ D I VM DG ++E+G++TELL   G+FA+F+RTY
Sbjct:    1 MGIDHFCSV--DGSDPFWDWNRT--WHTHNPDLTQCFQNTLLVVVPCFYLWLFAPFY---------FLYLKSHDRGYICMTHLNKAKTVTGFLLWIICWADVFYSFWERGHGVASAPVYLVSPTILGITMLLATLLIQYERIKGVQSSGIMLNFWLVATVCATVTFRSK----------ILQAVNEP-ETVNVFR------YSTFYIYYALLLISLILSCLSDQPPLFSQAVKDSN------PCPEAGASFLSRISFWWITGLMVQGYKRPLEEKDLWSLNAEDRSHTVVPQLVRRWDHECSKGKRTDDKTMYSPKRPSMAEKKDG-----RPV----EESEILLIKAPQKSG-----DPSLFLALCRTFGPYFLVSSIYKIIHDVLMFVGPEILRLLIQFVNDSDAPSWHGYFYTALLFVCTCFQTLILQKYFHVCFVTGMRLRTAIVGAVYRKALVITNAARRTSTVGEIVNLMSVDAQRFMDLITYINMIWSAPLQVILALYFLWQNLGPSVLAGVAVMVLMVPVNAVIAMKTKTYQVAQMKSKDNRIKLMNEVLNGIKVLKLYAWELAFKDKVSTIRESELRVLKKAAYLGAISTFTWVCAPFLVALSTFAVYVLVDEHNVLDAQKAFVSLALFNILRFPLNMLPMVISSMVQASVSMKRLRVFLSHEELDENSVDRRAITGSADSIRIGDGAFSWSKEDRPALKRINVRIPEGALVAVVGHVGSGKSSLLSALLGEMHKQEGDVSIKGSVAYVPQQAWIQNATLRENIMFGQEKKESWYQKVLEACALLPDLEILPGGDTTEIGEKGVNLSGGQKQRVSLARAVYCDCSVYLLDDPLSAVDAHVGKHIFEKVIGPQGVLQGRTRVLVTHGLSFLPQADLILVMVDGEITETGSYTELLNRQGAFADFLRTY 866

HSP 2 Score: 610.142 bits (1572), Expect = 0.000e+0
Identity = 293/581 (50.43%), Postives = 422/581 (72.63%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A  G VK +VF  Y+++     SF  +  +  +   S+G+N +LS WT+    NGTQ   S+   LG+YG+LG  Q + +   + +++ G  LAS+ LH  +L N+LR+P SFF+ TP G ++NR  K+ DT+D  IP+ I++++ +   V+GS  VI I++P   + + PL  +Y+  QRFY+ +SRQLKR++S+ RSP+Y+HF E+++G S IRA+     FI + D   D NQ A++P+IV+ RWL   LE +GN ++  + + AV+ R+ +  G  GLSISYALQ+T  LN++VRM+S++E++ VAVER+KEY + E EA W +E+S   + WP +G +E  N+ +RYR  L+L + ++ ++++ GEK+GIVGRTGAGKSSL L LFR+IE A+G I ID  +I  LGLHDLRS+ITIIPQDP+LFSG++RMNLDPF+ +SD ++W  LE+++LK+F++   + L +  SEGGENLS+GQ+QLVCLARALL+K+K+LVLDEATAAVDLETD+LIQS+IR QF+ CTVLTIAHRLNTIMDY RV+VL++G++ E DSP +L+A +K IF+ MA D+GL
Sbjct:  953 ANTGRVKLAVFWEYMKAIGVFLSFISILLFLAHHVSSLGSNYWLSLWTDDPVINGTQ--PSREMRLGVYGALGLSQGIAVFCYSISVSIGGILASRYLHETMLYNVLRSPMSFFERTPSGNLVNRFAKETDTIDSVIPSIIKMFMGSMFNVLGSCAVILIATPLVAIIIPPLGLLYFFVQRFYVASSRQLKRLESVSRSPVYTHFNETLLGTSVIRAFGEQQRFIGESDRRVDHNQKAYFPSIVANRWLAVRLEFVGNCIVTFAALFAVMARANLSPGIMGLSISYALQVTASLNWLVRMSSEVETNIVAVERVKEYEDTEKEAEWKLEQSSVPAGWPTAGHIEVRNFGLRYREDLELAIHDITVIIEGGEKVGIVGRTGAGKSSLTLGLFRIIEAAQGEICIDGVNIANLGLHDLRSRITIIPQDPVLFSGSLRMNLDPFDGYSDEDVWRALELAHLKNFVSGLPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGKMAEFDSPASLIA-KKGIFYKMAKDSGL 1530

HSP 3 Score: 75.485 bits (184), Expect = 4.741e-13
Identity = 74/284 (26.06%), Postives = 126/284 (44.37%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVE--FVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIF 4717
            LN +  + S +   +V+++R++ +   E E   N  + +A +   DS R+     ++S   RP L    + +N+ +  G  + +VG  G+GKSSL  AL   +   EG + I             +  +  +PQ   + + T+R N+    +  +     VLE   L   +     G    + E G NLS GQKQ V LARA+     V +LD+  +AVD      I   +   +   +  T + + H L+ +   D ++V+  G + E  S   LL N +  F
Sbjct:  595 LNMLPMVISSMVQASVSMKRLRVFLSHE-ELDENSVDRRAITGSADSIRIGDGAFSWSKEDRPAL----KRINVRIPEGALVAVVGHVGSGKSSLLSALLGEMHKQEGDVSI-------------KGSVAYVPQQAWIQNATLRENIMFGQEKKESWYQKVLEACALLPDLEILPGGDTTEIGEKGVNLSGGQKQRVSLARAVYCDCSVYLLDDPLSAVDAHVGKHIFEKVIGPQGVLQGRTRVLVTHGLSFLPQADLILVMVDGEITETGSYTELL-NRQGAF 859

HSP 4 Score: 60.4622 bits (145), Expect = 2.008e-8
Identity = 53/213 (24.88%), Postives = 86/213 (40.38%), Query Frame = 2 
Query: 2099 NINMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            +I + +  G  V +VG  G+GK+SL   L   +    G +               R  I  IPQ     + SL+ N+       +    R +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G ++E  +   L+   G F
Sbjct: 1312 DITVIIEGGEKVGIVGRTGAGKSSLTLGLFRIIEAAQGEICIDGVNIANLGLHDLRSRITIIPQDPVLFSGSLRMNLDPFDGYSDEDVWRALELAHLKNFVSGLPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTI---RTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGKMAEFDSPASLIAKKGIF 1521
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Cavefish
Match: abcc1 (ATP binding cassette subfamily C member 1 [Source:NCBI gene;Acc:103043969])

HSP 1 Score: 745.347 bits (1923), Expect = 0.000e+0
Identity = 393/916 (42.90%), Postives = 572/916 (62.45%), Query Frame = 2 
Query:   26 MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIY---RNRGKFNIFKSTLIAFILFFHLLNFC-----ATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQT--------KFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSP--PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            MG  HF S+  D S+ +  W     W+T +PD+T CFQ T+L  +P  +LW+    Y         F+Y    +RG   +        +  F L   C      +  E    +   P   + P +  I+ +L   L +    KG+ SSG++  +WL+  + +     S+          + + V    E + VF       ++   ++     I+       +  PL S    D        PCPE   SFLS+++F W+TGL+++GY++PL  KDL++L   D   T+V  +  +W+ E  + K+T        K     EK++G     +P+    EE+EI  ++    +       PS   AL  T G  ++++ ++K+ +D+L F  P+IL L I F+++ +   WHG+     LF+ +  +++I Q+Y+H C+VTGMR RTA++G +YRKAL +++ +R+ +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +++A+YFLWQ LGPSVLAGVA+M+ ++P+N +I  K K  Q  QMK KDNRIKLMNE+L+GIK+LKLYAWE +F+  +  IR  E R+L+ A YL A+S  TW CAPFLVAL TF  + L    +VL A KAFVSL+LFNIL FP++MLP VI   +QA VS+KR+  FL  +ELD  +V+          ++I DG FSW K + P L  IN+ +PEG+LVAVVG VGSGK+SL+SAL+GE++K  G V  +GS+ Y+PQQAW +NA+L++NI+F +      Y +V+EACAL  DL++LP GD TEIGEKG+NLSGGQKQR+SLARAVY DCSVYLLDDPLSAVD+HVGKHIF++VIGP G+L  +TR+LVTHGL++LP+ D I VM DG ++E+G++TELL   G+FA+F+RTY
Sbjct:    1 MGIDHFCSV--DGSDPFWDWNRT--WHTHNPDLTQCFQNTLLVVVPCFYLWLFAPFY---------FLYLKSHDRGYICMTHLNKAKTVTGFLLWIICWADVFYSFWERGHGVASAPVYLVSPTILGITMLLATLLIQYERIKGVQSSGIMLNFWLVATVCATVTFRSK----------ILQAVNEP-ETVNVFR------YSTFYIYYALLLISLILSCLSDQPPLFSQAVKDSN------PCPEAGASFLSRISFWWITGLMVQGYKRPLEEKDLWSLNAEDRSHTVVPQLVRRWDHECSKGKRTDDKTMYSPKRPSMAEKKDG-----RPV----EESEILLIKAPQKSG-----DPSLFLALCRTFGPYFLVSSIYKIIHDVLMFVGPEILRLLIQFVNDSDAPSWHGYFYTALLFVCTCFQTLILQKYFHVCFVTGMRLRTAIVGAVYRKALVITNAARRTSTVGEIVNLMSVDAQRFMDLITYINMIWSAPLQVILALYFLWQNLGPSVLAGVAVMVLMVPVNAVIAMKTKTYQVAQMKSKDNRIKLMNEVLNGIKVLKLYAWELAFKDKVSTIRESELRVLKKAAYLGAISTFTWVCAPFLVALSTFAVYVLVDEHNVLDAQKAFVSLALFNILRFPLNMLPMVISSMVQASVSMKRLRVFLSHEELDENSVDRRAITGSADSIRIGDGAFSWSKEDRPALKRINVRIPEGALVAVVGHVGSGKSSLLSALLGEMHKQEGDVSIKGSVAYVPQQAWIQNATLRENIMFGQEKKESWYQKVLEACALLPDLEILPGGDTTEIGEKGVNLSGGQKQRVSLARAVYCDCSVYLLDDPLSAVDAHVGKHIFEKVIGPQGVLQGRTRVLVTHGLSFLPQADLILVMVDGEITETGSYTELLNRQGAFADFLRTY 866

HSP 2 Score: 609.757 bits (1571), Expect = 0.000e+0
Identity = 293/581 (50.43%), Postives = 422/581 (72.63%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A  G VK +VF  Y+++     SF  +  +  +   S+G+N +LS WT+    NGTQ   S+   LG+YG+LG  Q + +   + +++ G  LAS+ LH  +L N+LR+P SFF+ TP G ++NR  K+ DT+D  IP+ I++++ +   V+GS  VI I++P   + + PL  +Y+  QRFY+ +SRQLKR++S+ RSP+Y+HF E+++G S IRA+     FI + D   D NQ A++P+IV+ RWL   LE +GN ++  + + AV+ R+ +  G  GLSISYALQ+T  LN++VRM+S++E++ VAVER+KEY + E EA W +E+S   + WP +G +E  N+ +RYR  L+L + ++ ++++ GEK+GIVGRTGAGKSSL L LFR+IE A+G I ID  +I  LGLHDLRS+ITIIPQDP+LFSG++RMNLDPF+ +SD ++W  LE+++LK+F++   + L +  SEGGENLS+GQ+QLVCLARALL+K+K+LVLDEATAAVDLETD+LIQS+IR QF+ CTVLTIAHRLNTIMDY RV+VL++G++ E DSP +L+A +K IF+ MA D+GL
Sbjct:  939 ANTGRVKLAVFWEYMKAIGVFLSFISILLFLAHHVSSLGSNYWLSLWTDDPVINGTQ--PSREMRLGVYGALGLSQGIAVFCYSISVSIGGILASRYLHETMLYNVLRSPMSFFERTPSGNLVNRFAKETDTIDSVIPSIIKMFMGSMFNVLGSCAVILIATPLVAIIIPPLGLLYFFVQRFYVASSRQLKRLESVSRSPVYTHFNETLLGTSVIRAFGEQQRFIGESDRRVDHNQKAYFPSIVANRWLAVRLEFVGNCIVTFAALFAVMARANLSPGIMGLSISYALQVTASLNWLVRMSSEVETNIVAVERVKEYEDTEKEAEWKLEQSSVPAGWPTAGHIEVRNFGLRYREDLELAIHDITVIIEGGEKVGIVGRTGAGKSSLTLGLFRIIEAAQGEICIDGVNIANLGLHDLRSRITIIPQDPVLFSGSLRMNLDPFDGYSDEDVWRALELAHLKNFVSGLPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGKMAEFDSPASLIA-KKGIFYKMAKDSGL 1516

HSP 3 Score: 75.485 bits (184), Expect = 5.017e-13
Identity = 74/284 (26.06%), Postives = 126/284 (44.37%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVE--FVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIF 4717
            LN +  + S +   +V+++R++ +   E E   N  + +A +   DS R+     ++S   RP L    + +N+ +  G  + +VG  G+GKSSL  AL   +   EG + I             +  +  +PQ   + + T+R N+    +  +     VLE   L   +     G    + E G NLS GQKQ V LARA+     V +LD+  +AVD      I   +   +   +  T + + H L+ +   D ++V+  G + E  S   LL N +  F
Sbjct:  595 LNMLPMVISSMVQASVSMKRLRVFLSHE-ELDENSVDRRAITGSADSIRIGDGAFSWSKEDRPAL----KRINVRIPEGALVAVVGHVGSGKSSLLSALLGEMHKQEGDVSI-------------KGSVAYVPQQAWIQNATLRENIMFGQEKKESWYQKVLEACALLPDLEILPGGDTTEIGEKGVNLSGGQKQRVSLARAVYCDCSVYLLDDPLSAVDAHVGKHIFEKVIGPQGVLQGRTRVLVTHGLSFLPQADLILVMVDGEITETGSYTELL-NRQGAF 859

HSP 4 Score: 60.4622 bits (145), Expect = 1.987e-8
Identity = 53/213 (24.88%), Postives = 86/213 (40.38%), Query Frame = 2 
Query: 2099 NINMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            +I + +  G  V +VG  G+GK+SL   L   +    G +               R  I  IPQ     + SL+ N+       +    R +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   + +LD+  +AVD      I   +          T + + H L  +    ++ V+  G ++E  +   L+   G F
Sbjct: 1298 DITVIIEGGEKVGIVGRTGAGKSSLTLGLFRIIEAAQGEICIDGVNIANLGLHDLRSRITIIPQDPVLFSGSLRMNLDPFDGYSDEDVWRALELAHLKNFVSGLPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTI---RTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGKMAEFDSPASLIAKKGIF 1507
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Sea Lamprey
Match: abcc3 (ATP-binding cassette, sub-family C (CFTR/MRP), member 3 [Source:ZFIN;Acc:ZDB-GENE-050517-16])

HSP 1 Score: 674.085 bits (1738), Expect = 0.000e+0
Identity = 363/874 (41.53%), Postives = 527/874 (60.30%), Query Frame = 2 
Query:  116 PDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYS---RYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEE-EETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPD--EKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            PD+  CFQ T+L W+P  FLW++ + Y   L +     Y      +  K+ L A +          ++ E       PP  ++ P++   + +L   L ++    G+HSS +LF +WLL L+ +IT   S      RL   + D FR        +LV V FIL C A                   E +PL S   DD  +      CPE   SF+S+LTF W T + + GYR+ L   DL++LR  D+C  +V +++  W +E  R+ Q              S   P ++ +   TE               + PS +RA+    G  Y++  V+K+  D+L+FA P +L   I F+ + +   WHG+ LA  +FL ++  S++  Q++H  +VTG+R R+A+ G++YRKAL ++  +R     GE+  LMSVD Q + D+ + L+ +W+AP+ I +A+YFLWQ LGPSVLAGVA+M+ LIP N  I   ++ LQA+ +K +D R++ ++E LSG++I+K+YAWE  F   I  +R  E  +L  A Y + +SA TW C+PFLVAL +F  + L    HVL A +AFVSL+LFN+L +P++ LP ++     A VSL+R+  FL  +ELD   V+ SP    E  V I  GTF+W   E P+L +I++ VP G L+AVVGTVGSGK+SL++AL+GEL K+ G V  +G + Y+ QQAW +N SL+DN+LF +PL    Y  V++ACAL +DL  LPAGD TEIGEKGINLSGGQ+QR+SLARA+Y   SV+LLDDPLSAVD+HVGKHIF++VIGPSGLL+ +TR+LVTHGL++LP VD+I V+  G VSESG+++EL+ +  +F+E +R +
Sbjct:    8 PDVPACFQATVLVWVPCTFLWLAALPYFAWLRHHRQG-YIACSVLSRAKTVLCAILWLLCWAKLFFSLWERSQGQSLPPIFFISPLILGATMLLAAVLGQVERWSGVHSSALLFVFWLLVLVGAITGTRSSVLHAVRLGMLE-DPFRDTVFLMYSVLVLVQFILVCLA-------------------EKRPLFSTDSDDPNL------CPEVGASFISRLTFCWFTRMAVNGYRRGLKMSDLWSLRHKDSCSFVVPHLQAVWRKEQARIAQ----------RSAVSQSTPAETRKLHTTEKSQSGGAGTEGGATGQEPSLIRAMALAFGPRYLVGSVYKLLQDILSFASPLLLSHLIRFVGDNSRPTWHGYALAGLMFLCAIATSMLAHQHFHAGFVTGIRLRSALTGLLYRKALMITQAARLSCAGGELTTLMSVDVQHMADITNNLNFVWSAPLHICLAMYFLWQHLGPSVLAGVAVMLLLIPFNAFIALNIRTLQAQIIKKRDERVRTLSEALSGVRIIKMYAWEGRFRDVILRVREHELAVLGRAAYFSMLSAFTWLCSPFLVALASFGVYVLVDEHHVLDAERAFVSLALFNLLRYPLNQLPQLMSELAMASVSLRRLRNFLSLEELDPHAVDRSPSHLRESCVSIEGGTFTWSWDEPPILHDISLAVPRGCLLAVVGTVGSGKSSLMAALLGELNKLGGSVAVKGQVAYVAQQAWIQN-SLRDNVLFGRPLDETWYREVLQACALEQDLLALPAGDNTEIGEKGINLSGGQRQRVSLARAIYSKASVFLLDDPLSAVDAHVGKHIFERVIGPSGLLAGQTRVLVTHGLSFLPHVDRIVVLTAGRVSESGSYSELMLSGEAFSELLRIH 843

HSP 2 Score: 573.933 bits (1478), Expect = 7.745e-178
Identity = 288/581 (49.57%), Postives = 396/581 (68.16%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWL-QFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            E G +K SV L Y+R+     S   +  +       +G N++LS W      NGTQ   + G+ LG+Y +LGA Q++  L+    +  G   A+ SLH  LL N L +P SF+D TPLGRI+NR  KD+  +D  +P T  ++L      I +I +I IS+P F++A +PL  +Y+  QRFY+ TSRQLKR++S  RSP++SHF ES+ GA+++RA++  + F+   D   D  Q   YP+IVS R +   +LE +G  V+L + + AV++R ++ +G  GLS+SYA+Q+T  +++MVRM+S++ES+ VAVER+KEY+E   EA W +E  +  +DWP  G VEF +YS RYR GLDLVLRN++  +  GEK+GIVGRTGAGKSSL L L R++E A G I ID  DI+++GLHDLRS+ITIIPQDP+LF G++R NLDPF  HSD E+W  LE ++L         G+Q+  +EGGEN SVGQ+QL CLARALL++++VLVLDEATAAVD+ETD LIQ +IR  F  CTVLTIAHRL+T++D  RVMVL  G++ E DSP  LL+ + S FH MA DAG+
Sbjct:  937 ETGHMKLSVVLHYLRAVGAPLSTLALLLFCANYTTMLGTNVWLSEWAGEPVVNGTQR--NTGYRLGVYSALGAVQSVLSLVMVLMVFKGCLRAAGSLHLALLDNKLHSPISFYDVTPLGRIINRFSKDVFMIDEVLPPTFLMFLGALCNSIFTILIIVISTPVFVVAAIPLVVIYFFVQRFYVATSRQLKRLESTVRSPVFSHFGESVAGAATLRAFRQEERFVIAGDRAVDALQRTSYPSIVSQRRVGAVWLEFLGACVVLFAAMFAVLSRDSLKAGTVGLSVSYAMQVTVVMSWMVRMSSEVESNIVAVERVKEYSETPPEADWEVESCRPPADWPSQGHVEFRDYSTRYREGLDLVLRNISCDIKGGEKVGIVGRTGAGKSSLTLCLLRMVEAASGAIAIDGVDISRIGLHDLRSRITIIPQDPVLFGGSLRDNLDPFGHHSDAEVWEALEFAHLGETARALPGGIQHECAEGGENFSVGQRQLACLARALLRRTRVLVLDEATAAVDVETDALIQGTIRTHFHACTVLTIAHRLHTVLDCTRVMVLSSGQIVEFDSPDVLLSRKDSAFHKMARDAGI 1515

HSP 3 Score: 80.4925 bits (197), Expect = 3.118e-15
Identity = 116/476 (24.37%), Postives = 193/476 (40.55%), Query Frame = 2 
Query: 1376 TTVGEIVNLMSVDSQKLQDV--PSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDEC-RILRSATYLNAVS----AVTWFCAPFLVA-LCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFL-VGDELDTENVEVSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEA---CALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELL-KNNGSFAEFIR 2713
            T +G I+N  S D   + +V  P+FL  L  A    +  I  +       V+A + L++    +     +  ++L+  +  ++        E ++G   L+ +  E  F      I  D     L+  +Y + VS       W    FL A +  F A     S   L A    +S+S    ++  MS +  +        V+++R+ ++     E D E     PP + P    V+  D +  + +    VL NI+ ++  G  V +VG  G+GK+SL   L+  +   SG +               R  I  IPQ       SL+DN+    P  +H    V EA     L E  + LP G Q E  E G N S GQ+Q   LARA+ +   V +LD+  +AVD      I   +        + T + + H L  +    ++ V+  G + E  +   LL + + +F +  R
Sbjct: 1050 TPLGRIINRFSKDVFMIDEVLPPTFLMFL-GALCNSIFTILIIVISTPVFVVAAIPLVVIYFFVQRFYVATSRQLKRLESTVRSPVFSHFGESVAGAATLRAFRQEERFV-----IAGDRAVDALQRTSYPSIVSQRRVGAVWL--EFLGACVVLFAAMFAVLSRDSLKAGTVGLSVSYAMQVTVVMSWMVRMSSEVESNIVAVERVKEYSETPPEADWEVESCRPPADWPSQGHVEFRDYSTRYREGLDLVLRNISCDIKGGEKVGIVGRTGAGKSSLTLCLLRMVEAASGAIAIDGVDISRIGLHDLRSRITIIPQDPVLFGGSLRDNL---DPFGHHSDAEVWEALEFAHLGETARALPGGIQHECAEGGENFSVGQRQLACLARALLRRTRVLVLDEATAAVDVETDALIQGTI---RTHFHACTVLTIAHRLHTVLDCTRVMVLSSGQIVEFDSPDVLLSRKDSAFHKMAR 1511

HSP 4 Score: 74.7146 bits (182), Expect = 1.674e-13
Identity = 71/277 (25.63%), Postives = 125/277 (45.13%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELW--SVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            LN + ++ S+L   +V++ R++ +  +E   P  ++ S +H        V     +  +      +L ++++ V  G  L +VG  G+GKSSL  AL   +    G++ +             + ++  + Q   +   ++R N+  F +  D E W   VL+   L+  +     G    + E G NLS GQ+Q V LARA+  K+ V +LD+  +AVD      I   +          T + + H L+ +   DR++VL  GRV E  S   L+
Sbjct:  573 LNQLPQLMSELAMASVSLRRLRNFLSLEELDPHAVDRSPSHLR---ESCVSIEGGTFTWSWDEPPILHDISLAVPRGCLLAVVGTVGSGKSSLMAALLGELNKLGGSVAV-------------KGQVAYVAQQAWI-QNSLRDNV-LFGRPLD-ETWYREVLQACALEQDLLALPAGDNTEIGEKGINLSGGQRQRVSLARAIYSKASVFLLDDPLSAVDAHVGKHIFERVIGPSGLLAGQTRVLVTHGLSFLPHVDRIVVLTAGRVSESGSYSELM 830
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007076.1 (pep scaffold:Pmarinus_7.0:GL480539:10051:22495:1 gene:ENSPMAG00000006379.1 transcript:ENSPMAT00000007076.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 444.891 bits (1143), Expect = 4.626e-141
Identity = 235/521 (45.11%), Postives = 332/521 (63.72%), Query Frame = 2 
Query: 3155 STNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIG--SGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKS 4711
            S NG+   D   FYL +YG+L AG  +F L+  F  AYG   A+K++H  LL  +L+AP SFFD TP GRI+NR   D+ TVD S+P  + I++    G++G+I V+    P+  L L+PL  +YY  Q++Y +TSR+LKR+ S+  SPIYSHF ES+ G + I+A++ +D F ++ +   + NQ   +  +    WL   L+ +G ++++    LAV+     G   G  GL+I+YAL I G L+ +V   +  E+  V+VER++EY  I SE       +    DWP  G + F    + YRPGL   L  ++  +++ EK+GIVGRTG+GKS+L   LFR+++   G I IDN+DI+KL L  LRS + IIPQDP LFS T+R NLDP   + D ELW VLE  +LKSF+     GLQ  V+E G + S GQ+QL+CLARA+L K+K+L +DEATA+VD +TD L+Q +IR +F   TVLTIAHR NTI+D DRV+VL+ GRV E  SP +LL + +S
Sbjct:   11 SANGS---DPVQFYLSVYGALAAGNTVFTLLRAFLFAYGGVCAAKNIHVTLLHKVLQAPVSFFDATPTGRIMNRFSSDLFTVDDSLPFIMNIFMAQLFGLVGAIVVMCYGLPWMALVLLPLAGVYYCVQKYYRFTSRELKRLGSVTLSPIYSHFAESLSGLAIIKAFRATDRFTRENEARLELNQRCQFAAVAVMHWLDVRLQMMGVVIVVSLAALAVLEHHLRGVDPGLVGLAIAYALGINGRLSGLVSSFTQTETQMVSVERVQEYRGIASEEAHR-HPTHVSPDWPQGGALTFDKVFLTYRPGLPFALNGISFCINSWEKVGIVGRTGSGKSTLFSVLFRIVDVQHGAIYIDNQDISKLALKQLRSNLAIIPQDPFLFSDTVRNNLDPKGSYQDHELWEVLEKCHLKSFVLDQG-GLQAEVAERGRDFSCGQRQLLCLARAMLFKAKILCIDEATASVDQDTDVLLQKTIRSEFVNSTVLTIAHRPNTILDSDRVLVLQGGRVLEFASPHDLLQDPRS 526

HSP 2 Score: 70.4774 bits (171), Expect = 1.876e-12
Identity = 110/484 (22.73%), Postives = 204/484 (42.15%), Query Frame = 2 
Query: 1331 IYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPI-----TIVIAIYFL-WQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRI-LRSATYLNAVSAVTWFCAPF----LVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQA---YVSLKRINKF--LVGDELDTENVEVSPP-DEKPVKIVDGTFSWGKTEAPVLIN-INMEVPEGSLVAVVGTVGSGKTSLISALI-------GELY-------KVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKN 2686
            +  K L+   +    T  G I+N  S D   + D   F+  ++ A +      IV+  Y L W  L    LAGV    C+         ++K+L +  +    +      E LSG+ I+K +   + F       R +E R+ L       AV+ + W         +V + +  A  +    H+   +   V L++   L      L G++    Q     VS++R+ ++  +  +E       VSP   +      D  F   +   P  +N I+  +     V +VG  GSGK++L S L        G +Y       K++ + + R ++  IPQ  +  + ++++N+       +H+   V+E C L +   +   G Q E+ E+G + S GQ+Q + LARA+     +  +D+  ++VD      +  Q    S  ++S T + + H    +   D++ V++ G V E  +  +LL++
Sbjct:   58 LLHKVLQAPVSFFDATPTGRIMNRFSSDLFTVDDSLPFIMNIFMAQLFGLVGAIVVMCYGLPWMALVLLPLAGV--YYCVQKYYRFTSRELKRLGSVTLSPIYSHFA---ESLSGLAIIKAFRATDRFT------RENEARLELNQRCQFAAVAVMHWLDVRLQMMGVVIVVSLAALAVLEH-HLRGVDPGLVGLAIAYALGIN-GRLSGLVSSFTQTETQMVSVERVQEYRGIASEEAHRHPTHVSPDWPQGGALTFDKVFLTYRPGLPFALNGISFCINSWEKVGIVGRTGSGKSTLFSVLFRIVDVQHGAIYIDNQDISKLALKQL-RSNLAIIPQDPFLFSDTVRNNLDPKGSYQDHELWEVLEKCHL-KSFVLDQGGLQAEVAERGRDFSCGQRQLLCLARAMLFKAKILCIDEATASVDQDT--DVLLQKTIRSEFVNS-TVLTIAHRPNTILDSDRVLVLQGGRVLEFASPHDLLQD 523
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006454.1 (pep scaffold:Pmarinus_7.0:GL483531:32:7621:1 gene:ENSPMAG00000005809.1 transcript:ENSPMAT00000006454.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 431.024 bits (1107), Expect = 1.729e-136
Identity = 218/490 (44.49%), Postives = 316/490 (64.49%), Query Frame = 2 
Query: 3269 GTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAE-IESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAG-KSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAV 4732
            GT  AS  LH+ L   +LR+  + FDTTP GR+LNR  +D+D VDV +P    +++     V+  + VI+   P+FLLA++PL  ++ +  +      R+LKR+D+I  SP  SH   S+ G  +I AY  SD+F+ +   + D NQ   +    + RWL   L+ I   +I  + ++ V+    I + YAGL+ISYA+Q+TG   + +R+ S+ E+   +VERI+ Y E +E EAP ++ E    ++WP  G V F +  +RYR GL LVL+ +   +   E +GIVGRTG+G KSSL + LFRL+E   G+I ID   I  +GL DLRS+++IIPQ+P+LF GTIR NLDP   ++D ++W  LE +++K  I +  + L+  V E GEN SVG++QL+C+ARA+L+ SK+L+LDEATAA+D ETD LIQ +IRR F  CT+LTIAHRLNT++  DR+MV++QG+V E DSP  LL N  S F +M V
Sbjct:    3 GTLRASSRLHDSLFLKVLRSSMTVFDTTPTGRLLNRFSRDMDEVDVRMPFQAELFIQNVILVLFCLGVIAAVFPWFLLAVIPLCVLFLIINKISRVFIRELKRLDNISHSPFMSHVAASLQGLPTIHAYSKSDEFLHRYQELLDTNQACLFLFSCAVRWLAVRLDIISVALITTTALMMVLMHGQIPAAYAGLAISYAIQLTGTFQFTIRLASETEARFTSVERIQHYIEALEEEAPDHVPEKPLAAEWPQHGSVSFQDVEMRYREGLPLVLKRVTANIKPRENVGIVGRTGSGCKSSLGVCLFRLVELCGGSISIDGVPIGDIGLGDLRSRLSIIPQEPVLFIGTIRTNLDPLGLYTDEQIWEALERTHMKDNIGQLPQKLETEVVENGENFSVGERQLLCVARAILRHSKILLLDEATAAIDTETDTLIQETIRRAFGDCTMLTIAHRLNTVLSCDRIMVMDQGQVVEFDSPSTLLENRASRFAAMMV 492

HSP 2 Score: 78.9518 bits (193), Expect = 3.540e-15
Identity = 114/511 (22.31%), Postives = 204/511 (39.92%), Query Frame = 2 
Query: 1301 MRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIV------IAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDN--RIKLMNEI---LSGIKILKLYAWENSFEQNIQNI--RNDECRILRSATYLNAVSAVTWFCAPF---LVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIV------DGTFSWGKTEAP-------VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC--------------RGSIGYIPQQAWCRNASLQDNILFSKPL---INHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            +R+ + +   ++ K L+ S T    T  G ++N  S D  ++     F   L+   + +V      IA  F W      +LA + L +  + IN     K+ ++  +++K  DN      M+ +   L G+  +  Y+  + F    Q +   N  C  L S        AV W         VAL T TA  +      + A  A +++S    L+        +       + S++RI  ++       E +E   PD  P K +       G+ S+   E         VL  +   +     V +VG  GSG  S +   +  L ++ G  +               R  +  IPQ+      +++ N+    PL    + +    +E   + +++  LP   +TE+ E G N S G++Q + +ARA+ +   + LLD+  +A+D+     I + +    G     T + + H L  +   D+I VM  G V E  + + LL+N  S
Sbjct:    5 LRASSRLHDSLFLKVLRSSMTVFDTTPTGRLLNRFSRDMDEVDVRMPFQAELFIQNVILVLFCLGVIAAVFPW-----FLLAVIPLCVLFLIIN-----KISRVFIRELKRLDNISHSPFMSHVAASLQGLPTIHAYSKSDEFLHRYQELLDTNQACLFLFSC-------AVRWLAVRLDIISVALITTTALMMVLMHGQIPAAYAGLAISYAIQLTGTFQFTIRLASETEARFTSVERIQHYI-------EALEEEAPDHVPEKPLAAEWPQHGSVSFQDVEMRYREGLPLVLKRVTANIKPRENVGIVGRTGSGCKSSLGVCLFRLVELCGGSISIDGVPIGDIGLGDLRSRLSIIPQEPVLFIGTIRTNL---DPLGLYTDEQIWEALERTHMKDNIGQLPQKLETEVVENGENFSVGERQLLCVARAILRHSKILLLDEATAAIDTETDTLIQETIRRAFG---DCTMLTIAHRLNTVLSCDRIMVMDQGQVVEFDSPSTLLENRAS 485
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001536.1 (pep scaffold:Pmarinus_7.0:GL479104:2125:31869:1 gene:ENSPMAG00000001392.1 transcript:ENSPMAT00000001536.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 395.201 bits (1014), Expect = 3.083e-123
Identity = 203/513 (39.57%), Postives = 324/513 (63.16%), Query Frame = 2 
Query: 3194 YLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVT--RSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEA-PWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHS 4723
            Y  ++G L         I +  + +     ++++HN +LK I+ AP  +FDTTPLG ILNR   D + +D  IPTT+   + +A   + ++ +I+  +P FL+ALVPL   YY  Q+++   SR L+ +D   + P++SHF E++ G ++IRA++    F ++   +TD N +++     + RWL+  L+ IG  ++L++ V ++     +T+ S   GL ++YAL ++  LN++VR  +D+E    A++R+    +IE+E+    + ++Q   +WP SG ++    SVRY   L  VL+++N  +   +K+GI GRTG+GKSSL+LA FR+++  EG IIIDN DI K+ LH LRS+++II QDPILFSG+IR NLDP     DG LW  L+++ LK  +     GL  +V+E GEN SVGQ+QL CLARA ++K+ + ++DEATA++D+ T+ ++Q  +   F   TV+ IAHR++TI+  D VMVL++G V E D+P  LLA++ S+F S
Sbjct:    2 YPMVFGLLCCSGIALCFITSLTVEWTGLKTARNVHNNMLKRIVLAPMRYFDTTPLGHILNRFSADTNIMDQQIPTTLESLMRSALLCLSALGIIAYVTPIFLIALVPLAIAYYFIQKYFRVASRDLQELDDSTQLPLFSHFSETVEGITTIRAFRHEVRFRQRLLELTDANNISYLFLSAANRWLEVRLDYIGACIVLIASVASITDSWNNTLSSARVGLCLTYALMVSNYLNWVVRNLADIEVQMGAIKRVNNLLQIETESYDGLLSQAQVPDNWPQSGEIKIEELSVRYDSTLKPVLKHVNAHIQPSQKVGICGRTGSGKSSLSLAFFRMVDTFEGRIIIDNIDIAKIPLHTLRSRLSIILQDPILFSGSIRFNLDPEAACGDGVLWEALDIAQLKHVVKALPGGLDAMVTENGENFSVGQRQLFCLARAFVRKTSIFIMDEATASIDMATESILQKVVMTAFANRTVVIIAHRVHTILTADLVMVLKRGSVLEYDTPSTLLAHD-SMFAS 513

HSP 2 Score: 99.3673 bits (246), Expect = 1.267e-21
Identity = 120/491 (24.44%), Postives = 214/491 (43.58%), Query Frame = 2 
Query: 1376 TTVGEIVNLMSVDSQKL-QDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIP--INGIIGSKVKKLQAKQMKMKDNRIKL-----MNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWF---------CAPFLVALCTFTAF---TLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENV-----EVSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-SIGYIPQQAWCRNAS--LQDNILFSKPLINHKYNRVIEACA-------------LTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIR 2713
            T +G I+N  S D+  + Q +P+ L  L  + +  + A       LG         +I L+P  I      K  ++ ++ ++  D+  +L      +E + GI  ++ +  E  F Q +  + +       + +YL   +A  W          C   + ++ + T     TLSS+   L    A   L + N L++ +  L  + V       ++KR+N  L   +++TE+      +   PD  P    +KI + +  +  T  PVL ++N  +     V + G  GSGK+SL  A    +    GR++     I  IP        S  LQD ILFS  +   ++N   EA               L   +K LP G    + E G N S GQ+Q   LARA  +  S++++D+  +++D    + I  +V+  +   +++T +++ H +  +   D + V+K G+V E  T + LL ++  FA F+R
Sbjct:   54 TPLGHILNRFSADTNIMDQQIPTTLESLMRSALLCLSA-------LGIIAYVTPIFLIALVPLAIAYYFIQKYFRVASRDLQELDDSTQLPLFSHFSETVEGITTIRAFRHEVRFRQRLLELTDAN-----NISYLFLSAANRWLEVRLDYIGACIVLIASVASITDSWNNTLSSARVGLCLTYA---LMVSNYLNWVVRNLADIEV----QMGAIKRVNNLL---QIETESYDGLLSQAQVPDNWPQSGEIKIEELSVRYDSTLKPVLKHVNAHIQPSQKVGICGRTGSGKSSLSLAFFRMVDTFEGRIIIDNIDIAKIPLHTLRSRLSIILQDPILFSGSI---RFNLDPEAACGDGVLWEALDIAQLKHVVKALPGGLDAMVTENGENFSVGQRQLFCLARAFVRKTSIFIMDEATASID-MATESILQKVVMTA--FANRTVVIIAHRVHTILTADLVMVLKRGSVLEYDTPSTLLAHDSMFASFVR 516
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Sea Lamprey
Match: ABCC8 (ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59])

HSP 1 Score: 380.178 bits (975), Expect = 1.009e-108
Identity = 208/550 (37.82%), Postives = 326/550 (59.27%), Query Frame = 2 
Query: 3116 GANMFLSYWTETGSTNGTQNPDS---------QGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRS---TIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQA-HSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSM 4726
              + +L+ WT        QN +          Q     I+  L     +  LI + A+ +    A++ LH  LL  I+RAP  FFDTTPLG ILNR   D+  +D  IP++    + ++   + ++ VI+  +P FL+ALVPL  ++Y  Q+ +   S+ L+ +D   + P+  H  E++ G ++IRA++    F ++   + D N + +     + RWL+  ++ IG  ++L +  +A +TRS    + SG  GL ++YAL ++  LN++VR  +D+E    A++R+    ++E E      E  A   DWP  G ++    S RY   L   L+NL+ V+  G+K+GI GRTG+GKSSL+LALFR+++  +G+I ID+ DI+K+ L  LRS+++II QDP+LFSG+IR NLDP  + +D  LW  LE++ LK  +     GL   V EGGEN S+GQ+QL CLARA ++++ +L++DEATAA+D+ T+ ++Q  +   F   TV+ IAHR+  I+D D V+VL QG ++E DSP NLLAN  +IF S+
Sbjct: 1025 APDFWLAMWTSRALNVTAQNHNCTSSSVCLCLQSLLASIFAVLCCLAVVMCLISSLAVEWVGLKAARGLHKRLLGRIVRAPLRFFDTTPLGSILNRFSADLHMIDQLIPSSTESLVRSSLFSLSAVSVIAYVTPIFLVALVPLALVHYFIQKHFRIASKDLQELDENTKLPLLLHIMETVDGIATIRAFRHESQFRQRIFELIDANNVPFLFLSAANRWLEVRMDYIGASIVLATA-MASITRSFYSGLDSGLVGLGLTYALLVSIYLNWVVRNLADIEVQLQAIKRVNNLMKVEIEDDERSPELHAVPEDWPHRGEIKINRLSARYDASLKPALKNLSSVIQPGQKVGICGRTGSGKSSLSLALFRMLDIFDGSITIDDVDISKIPLSLLRSRLSIILQDPVLFSGSIRFNLDPEARSTDSMLWDALEIAQLKCVVKALPGGLDATVREGGENFSLGQRQLFCLARAFVRQTAILIMDEATAALDMATEKILQKVVMTAFADRTVVMIAHRVANILDADVVLVLNQGLLEENDSPANLLANPDTIFSSL 1573

HSP 2 Score: 350.132 bits (897), Expect = 6.726e-99
Identity = 215/646 (33.28%), Postives = 329/646 (50.93%), Query Frame = 2 
Query: 1055 PSFLRALFHTIGYPYMLAGVFKVAYDLLTFA-------------------QPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLS--STSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFT-LSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFL----VGDELDTENVEVSPPD-----------------EKPV------------------------KIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRV------------------------MCR--GSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTR--ILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEF 2707
            PS  R++F T G P +++ V +   DLL F                    +PQ+  L + FI +  +++ + ++L++ LF   +++  + Q  Y+    TG++ R AV  +IY K L LS  S SR + T   I N+++VDS +L         LW  P+ I++ +  L+  LG S L G A++  L P+   I +K+ + Q   ++   +RIK  +E++ GIK+LKLYAWE  F   ++  R+ E R L +     A+S       P    + TF  +  LSS    L+   AF SL+LF+IL  P+ +L  V+ + ++A +S++++ +FL    +GDE +T +VE  P                   +KPV                        K+  G F+W  +E  +L +IN+ +P G L  VVG +G GK+SL+SA +GE++ VSG V                         CR  GS+ Y  Q+ W  N+++Q+NI F  P    +Y  VI  C+L  D+ +LP GD+T+IGEKGINLS GQ+QRIS+ARA+YQ  +V  LDDP +A+D H+  H+     G  GLL + TR  +LVTH L YL   D I  MKDG V   GT  ++  ++    E 
Sbjct:  284 PSLWRSVFRTFGRPIIVSSVLRYMADLLAFTGPLCIYGIVHHLNNDEQQLKPQVRALGVYFISS-REFLANAYVLSVLLFFSLVLQRTLLQASYYKAIETGIKFRAAVQTMIYDKILHLSTSSVSRGKMTSRYISNVVTVDSNQLMWFLFLCPNLWALPVQIIVGVSLLYSLLGVSALIGAAVIALLAPLQYCIATKLARAQKLTLEHSSSRIKQTSELVHGIKLLKLYAWEQVFCSTVEETRSKELRSLSTFAIYTALSTFMNAAIPITAVMATFVTYVHLSSPDITLSPAVAFASLALFHILVTPLFLLSTVVRFAVKALISMQKLTEFLATSEIGDEPNTLDVEPRPKKSSNADVVQMMAVNRKQPQKPVWDDFEPPQDWRQFEFTDGSEDFAIKVTGGVFTWASSEPSLLTDINICIPHGQLTMVVGQIGCGKSSLLSATLGEMHLVSGSVYWNSSPRQQSVNTKNNRQERRASTFCRRRGSVAYAAQKPWILNSNVQENITFGSPFNEERYKAVINTCSLQPDIDILPQGDRTQIGEKGINLSAGQRQRISVARALYQHTNVVFLDDPFTALDIHLSDHLMHS--GILGLLHNDTRTVVLVTHKLQYLTHADWIIAMKDGTVQREGTLKDIQTSDPELYEM 926

HSP 3 Score: 74.3294 bits (181), Expect = 2.330e-13
Identity = 71/279 (25.45%), Postives = 127/279 (45.52%), Query Frame = 2 
Query: 1958 SLKRINKFLVGDELDTENVEVSP-----PDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRG-SIGYIPQQAWCRNAS--LQDNILFSKPLINHKYN-------------RVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS-FAEFIRT 2716
            ++KR+N  +   +++ E+ E SP     P++ P    +KI   +  +  +  P L N++  +  G  V + G  GSGK+SL  AL   L    G +      I  IP        S  LQD +LFS  +   ++N               +E   L   +K LP G    + E G N S GQ+Q   LARA  +  ++ ++D+  +A+D    K I  +V+  +   + +T +++ H +  +   D + V+  G + E+ +   LL N  + F+  +++
Sbjct: 1307 AIKRVNNLM---KVEIEDDERSPELHAVPEDWPHRGEIKINRLSARYDASLKPALKNLSSVIQPGQKVGICGRTGSGKSSLSLALFRMLDIFDGSITIDDVDISKIPLSLLRSRLSIILQDPVLFSGSI---RFNLDPEARSTDSMLWDALEIAQLKCVVKALPGGLDATVREGGENFSLGQRQLFCLARAFVRQTAILIMDEATAALDMATEK-ILQKVVMTA--FADRTVVMIAHRVANILDADVVLVLNQGLLEENDSPANLLANPDTIFSSLVKS 1576

HSP 4 Score: 66.2402 bits (160), Expect = 7.094e-11
Identity = 55/233 (23.61%), Postives = 108/233 (46.35%), Query Frame = 2 
Query: 4076 VLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTI------------IIDNRDITKLG-LHDLRSKITIIPQDPILFSGTIRMNL---DPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLE-TDDLIQSSIRRQFKK--CTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIF 4717
            +L ++NI +  G+   +VG+ G GKSSL  A    +    G++              +NR   +       R  +    Q P + +  ++ N+    PFN+       +V+    L+  I    +G +  + E G NLS GQ+Q + +ARAL + + V+ LD+   A+D+  +D L+ S I         TV+ + H+L  +   D ++ ++ G V+   + +++  ++  ++
Sbjct:  695 LLTDINICIPHGQLTMVVGQIGCGKSSLLSATLGEMHLVSGSVYWNSSPRQQSVNTKNNRQERRASTFCRRRGSVAYAAQKPWILNSNVQENITFGSPFNEE---RYKAVINTCSLQPDIDILPQGDRTQIGEKGINLSAGQRQRISVARALYQHTNVVFLDDPFTALDIHLSDHLMHSGILGLLHNDTRTVVLVTHKLQYLTHADWIIAMKDGTVQREGTLKDIQTSDPELY 924
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Yeast
Match: YCF1 (Vacuolar glutathione S-conjugate transporter; ABC-C transporter of the ATP-binding cassette family; required for vacuole fusion; forms stable complexes with vacuole fusion machinery; regulates Vam7p recruitment to vacuoles; role in detoxifying metals (Cd, Hg, As); transports GSSG that is not immediately reduced in cytosol to vacuole; transports unconjugated bilirubin, selenodigluthatione, oxidized glutathione; similar to human cystic fibrosis protein CFTR [Source:SGD;Acc:S000002542])

HSP 1 Score: 556.599 bits (1433), Expect = 1.122e-171
Identity = 293/590 (49.66%), Postives = 416/590 (70.51%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRS----STYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFAL-AYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDF--IKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAV--VTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFI-AKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            E G VK++++L Y ++    S  +F   +V S    M  SV  N++L +W+E  S  G+ NP++   YL IY +LG G AL  LI+   L  + T  ASK LHNL+  ++LRAP +FF+TTP+GRILNR   DI  VD  +  T   + + A  V  +I VI  ++  F+  ++PL+  Y   Q++Y+ TSR+L+R+DSI RSPIYSHFQE++ G +++R Y     F  I +C I  D N  A+YP+I + RWL + LE IG+++IL +  L+V  + + T+ +G  GLS+SYALQIT  LN++VRMT ++E++ V+VERIKEYA+++SEAP  +E  +   +WP  G ++F NYS RYRP LDLVL+++NI +   EK+GIVGRTGAGKSSL LALFR+IE +EG I+IDN  I ++GL+DLR K++IIPQD  +F GT+R N+DP NQ++D  +W  LE+S+LK  + + +++GL   ++EGG NLSVGQ+QL+CLARA+L  SK+LVLDEATAAVD+ETD ++Q +IR  FK  T+LTIAHRLNTIMD DR++VL+ G+V E DSP  LL++ KS+F+S+ ++AGL
Sbjct:  930 EQGKVKWNIYLEYAKACNPKSVCVFILFIVIS----MFLSVMGNVWLKHWSEVNSRYGS-NPNA-ARYLAIYFALGIGSALATLIQTIVLWVFCTIHASKYLHNLMTNSVLRAPMTFFETTPIGRILNRFSNDIYKVDALLGRTFSQFFVNAVKVTFTITVICATTWQFIFIIIPLSVFYIYYQQYYLRTSRELRRLDSITRSPIYSHFQETLGGLATVRGYSQQKRFSHINQCRI--DNNMSAFYPSINANRWLAYRLELIGSIIILGAATLSVFRLKQGTLTAGMVGLSLSYALQITQTLNWIVRMTVEVETNIVSVERIKEYADLKSEAPLIVEGHRPPKEWPSQGDIKFNNYSTRYRPELDLVLKHINIHIKPNEKVGIVGRTGAGKSSLTLALFRMIEASEGNIVIDNIAINEIGLYDLRHKLSIIPQDSQVFEGTVRENIDPINQYTDEAIWRALELSHLKEHVLSMSNDGLDAQLTEGGGNLSVGQRQLLCLARAMLVPSKILVLDEATAAVDVETDKVVQETIRTAFKDRTILTIAHRLNTIMDSDRIIVLDNGKVAEFDSPGQLLSDNKSLFYSLCMEAGL 1511

HSP 2 Score: 449.129 bits (1154), Expect = 5.758e-133
Identity = 254/710 (35.77%), Postives = 398/710 (56.06%), Query Frame = 2 
Query:  680 LLSLIPDDKTIP--------INRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPN-----DY---------------VWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWF---CAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIV-----DGTFSWG-KTEAPV-LININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            LL  +P    +P          R P P +  +  S++TF+W++GL+  GY + L   DL+ L  N + + +   +E  W  E   +KQ                                            +PS   A+  T G   +LA  FK  +D+L F QPQ+L + I F+ + N     D+               +  GFL+A  +FL+   ++ +  QY+   + TGM  ++A+  +IY+K+L LS+ +   ++ G+IVNLMSVD QKLQD+  +L+++W+ P  I+I +Y L++ LG S+  GV +++ ++P+N  +    KKLQ  QMK KD R ++++EIL+ IK LKLYAWE  + + ++ +RN+  + L++ T L    AVT F     PFLV+ CTF  F + +    LT +  F +L+LFN+LSFP+ ++P V+   I+A VS+ R+  F   +EL  ++V+  P  +    +      D TF W  K E  V L NIN +  +G+L  +VG VGSGKT+L+S ++G+L++V G     GS+ Y+ Q  W  N ++++NILF        Y + I+ACALT DL +L  GD+T +GEKGI+LSGGQK R+SLARAVY     YLLDDPL+AVD HV +H+ + V+GP+GLL +KT++L T+ ++ L   D I ++ +G +++ GT+ E+ K+  S
Sbjct:  185 LLEALPKKPLMPHQHIHQTLTRRKPNPYDSANIFSRITFSWMSGLMKTGYEKYLVEADLYKLPRNFSSEELSQKLEKNWENE---LKQKS------------------------------------------NPSLSWAICRTFGSKMLLAAFFKAIHDVLAFTQPQLLRILIKFVTDYNSERQDDHSSLQGFENNHPQKLPIVRGFLIAFAMFLVGFTQTSVLHQYFLNVFNTGMYIKSALTALIYQKSLVLSNEASGLSSTGDIVNLMSVDVQKLQDLTQWLNLIWSGPFQIIICLYSLYKLLGNSMWVGVIILVIMMPLNSFLMRIQKKLQKSQMKYKDERTRVISEILNNIKSLKLYAWEKPYREKLEEVRNN--KELKNLTKLGCYMAVTSFQFNIVPFLVSCCTFAVF-VYTEDRALTTDLVFPALTLFNLLSFPLMIIPMVLNSFIEASVSIGRLFTFFTNEELQPDSVQRLPKVKNIGDVAINIGDDATFLWQRKPEYKVALKNINFQAKKGNLTCIVGKVGSGKTALLSCMLGDLFRVKGFATVHGSVAYVSQVPWIMNGTVKENILFGHRYDAEFYEKTIKACALTIDLAILMDGDKTLVGEKGISLSGGQKARLSLARAVYARADTYLLDDPLAAVDEHVARHLIEHVLGPNGLLHTKTKVLATNKVSALSIADSIALLDNGEITQQGTYDEITKDADS 846

HSP 3 Score: 78.9518 bits (193), Expect = 5.292e-15
Identity = 89/382 (23.30%), Postives = 166/382 (43.46%), Query Frame = 2 
Query: 1643 EILSGIKILKLYAWENSFEQNIQNIRNDECRILRS-ATYLNAVSAVTWFC-------APFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEV----SPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTED-LKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            E L G+  ++ Y+ +  F         ++CRI  + + +  +++A  W         +  ++   T + F L   +  LTA    +SLS    ++  ++ +  + V      VS++RI ++    +L +E   +     PP E P    +K  + +  +      VL +IN+ +     V +VG  G+GK+SL  AL   +    G ++              R  +  IPQ +     ++++NI       +    R +E   L E  L +   G   ++ E G NLS GQ+Q + LARA+     + +LD+  +AVD    K + + +         +T + + H L  +   D+I V+ +G V+E  +  +LL +N S 
Sbjct: 1134 ETLGGLATVRGYSQQKRFSHI------NQCRIDNNMSAFYPSINANRWLAYRLELIGSIIILGAATLSVFRLKQGT--LTAGMVGLSLSYALQITQTLNWIVRMTVEVETNIVSVERIKEY---ADLKSEAPLIVEGHRPPKEWPSQGDIKFNNYSTRYRPELDLVLKHINIHIKPNEKVGIVGRTGAGKSSLTLALFRMIEASEGNIVIDNIAINEIGLYDLRHKLSIIPQDSQVFEGTVRENIDPINQYTDEAIWRALELSHLKEHVLSMSNDGLDAQLTEGGGNLSVGQRQLLCLARAMLVPSKILVLDEATAAVDVETDKVVQETI---RTAFKDRTILTIAHRLNTIMDSDRIIVLDNGKVAEFDSPGQLLSDNKSL 1501

HSP 4 Score: 60.8474 bits (146), Expect = 1.881e-9
Identity = 59/227 (25.99%), Postives = 102/227 (44.93%), Query Frame = 2 
Query: 4058 RPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKL-GLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWS-VLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVD-----------LETDDLIQSSIR-RQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEI----DSP 4684
            +P   + L+N+N     G    IVG+ G+GK++L   +                D+ ++ G   +   +  + Q P + +GT++ N+  F    D E +   ++   L   +A   +G + LV E G +LS GQK  + LARA+  ++   +LD+  AAVD           L  + L+ +  +     K + L+IA   ++I   D   + +QG   EI    DSP
Sbjct:  639 KPEYKVALKNINFQAKKGNLTCIVGKVGSGKTALLSCMLG--------------DLFRVKGFATVHGSVAYVSQVPWIMNGTVKENI-LFGHRYDAEFYEKTIKACALTIDLAILMDGDKTLVGEKGISLSGGQKARLSLARAVYARADTYLLDDPLAAVDEHVARHLIEHVLGPNGLLHTKTKVLATNKVSALSIA---DSIALLDNGEITQQGTYDEITKDADSP 847
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Yeast
Match: BPT1 (ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p [Source:SGD;Acc:S000003938])

HSP 1 Score: 437.573 bits (1124), Expect = 1.105e-128
Identity = 249/605 (41.16%), Postives = 374/605 (61.82%), Query Frame = 2 
Query: 3005 EIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIEN-FALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIV-----SYRWLQFYLETIGNLVILLSGVLAVVTRST---IGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAK-----------------TSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAG 4741
            E+G VK  ++L+YI++   L          L     +  N +L YW+E+   NG+   +    ++G+Y  +G   A F  + +   L Y +   SK LH  + K+++R+P +FF+TTP+GRI+NR   D+D VD ++      +  +    + ++ ++  + P+FL+  + L  +Y   Q FYI  SR+LKR+ SI  SPI S   ES+ G S I AY   + FI       +  ++ +  + V     + RWL   L+TIG  ++L + +LA+ T +T   + SG  GL +SY+L++TG L ++VR T  +E++ V+VERI EY E+  EA     E +   +WP  G +EF NYS +YR  LD VL N+N+ ++  EK+GIVGRTGAGKS+L+LALFR++EP EG IIID  DI+ +GL DLRS + IIPQD   F GT++ NLDPFN++S+ EL   +E ++LK  + K                  ++ L   ++E G NLSVGQ+QL+CLARALL +SK+LVLDEATA+VD+ETD +IQ +IRR+FK  T+LTIAHR++T++D D+++VL+QG V+E DSP  LL+++ SIF+S+    G
Sbjct:  959 EVGRVKTKIYLAYIKACGVLGVVLFFLFMILTRVFDLAENFWLKYWSESNEKNGSN--ERVWMFVGVYSLIGVASAAFNNLRSIMMLLYCSIRGSKKLHESMAKSVIRSPMTFFETTPVGRIINRFSSDMDAVDSNLQYIFSFFFKSILTYLVTVILVGYNMPWFLVFNMFLVVIYIYYQTFYIVLSRELKRLISISYSPIMSLMSESLNGYSIIDAYDHFERFI-----YLNYEKIQYNVDFVFNFRSTNRWLSVRLQTIGATIVLATAILALATMNTKRQLSSGMVGLLMSYSLEVTGSLTWIVRTTVTIETNIVSVERIVEYCELPPEAQSINPEKRPDENWPSKGGIEFKNYSTKYRENLDPVLNNINVKIEPCEKVGIVGRTGAGKSTLSLALFRILEPTEGKIIIDGIDISDIGLFDLRSHLAIIPQDAQAFEGTVKTNLDPFNRYSEDELKRAVEQAHLKPHLEKMLHSKPRGDDSNEEDGNVNDILDVKINENGSNLSVGQRQLLCLARALLNRSKILVLDEATASVDMETDKIIQDTIRREFKDRTILTIAHRIDTVLDSDKIIVLDQGSVREFDSPSKLLSDKTSIFYSLCEKGG 1556

HSP 2 Score: 355.525 bits (911), Expect = 8.285e-101
Identity = 214/589 (36.33%), Postives = 331/589 (56.20%), Query Frame = 2 
Query: 1058 SFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVW---HGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRND-ECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPP--DEKPVKIVDG---TFSWGKTEA----------------------PVLININ-MEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGR--------VMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQV-IGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELL--KNNGS 2695
            S  RA++ + G    +A +++   DLL+  QPQ L +FI  ++      +   +G  +A+ LF+IS++   +  Q+Y G +  G+  R ++  ++Y+K+L+L+   R E + G+I+NLMSVD  ++Q        +  API I++ +  L+  LG +V+ G+  M  ++PIN  +  KVKKL   QMK KD RIK + E+L+ IK +KLYAWE      + ++RND E +  R    ++ +    W C P +V   TF  F+L S S  L+    F SLSLFNIL+  +  +P +I   I+  VS++R+  FL+ DE+D   +E   P  DE+ +  ++    TF W   E                         L NI+  E   G LV VVG VG+GK++ + A++G+L  +SG         ++   S+ Y  Q++W  NAS+++NILF        Y+  I+AC L  DLK+LP GD+T +GEKGI+LSGGQK R+SLARAVY    +YLLDD LSAVD+ V K+I + V IG + LL +KT IL T+ ++ L     I+ +++G + E G + +++  KNN S
Sbjct:  279 SLWRAIWKSFGRTISVAMLYETTSDLLSVVQPQFLRIFIDGLNPETSSKYPPLNGVFIALTLFVISVVSVFLTNQFYIGIFEAGLGIRGSLASLVYQKSLRLTLAERNEKSTGDILNLMSVDVLRIQRFFENAQTIIGAPIQIIVVLTSLYWLLGKAVIGGLVTMAIMMPINAFLSRKVKKLSKTQMKYKDMRIKTITELLNAIKSIKLYAWEEPMMARLNHVRNDMELKNFRKIGIVSNLIYFAWNCVPLMVTCSTFGLFSLFSDSP-LSPAIVFPSLSLFNILNSAIYSVPSMINTIIETSVSMERLKSFLLSDEIDDSFIERIDPSADERALPAIEMNNITFLWKSKEVLTSSQSGDNLRTDEESIIGSSQIALKNIDHFEAKRGDLVCVVGRVGAGKSTFLKAILGQLPCMSGSRDSIPPKLIIRSSSVAYCSQESWIMNASVRENILFGHKFDQDYYDLTIKACQLLPDLKILPDGDETLVGEKGISLSGGQKARLSLARAVYSRADIYLLDDILSAVDAEVSKNIIEYVLIGKTALLKNKTIILTTNTVSILKHSQMIYALENGEIVEQGNYEDVMNRKNNTS 866

HSP 3 Score: 72.7886 bits (177), Expect = 3.685e-13
Identity = 73/285 (25.61%), Postives = 126/285 (44.21%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVEVSP---PDEK-----PVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVM-------------CRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVL----PAGDQT-------------EIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            VS++RI ++    EL  E   ++P   PDE       ++  + +  + +   PVL NIN+++     V +VG  G+GK++L  AL   L    G+++              R  +  IPQ A     +++ N+         +  R +E   L   L+ +    P GD +             +I E G NLS GQ+Q + LARA+     + +LD+  ++VD    K I D +         +T + + H +  +   DKI V+  G+V E  + ++LL +  S
Sbjct: 1268 VSVERIVEYC---ELPPEAQSINPEKRPDENWPSKGGIEFKNYSTKYRENLDPVLNNINVKIEPCEKVGIVGRTGAGKSTLSLALFRILEPTEGKIIIDGIDISDIGLFDLRSHLAIIPQDAQAFEGTVKTNLDPFNRYSEDELKRAVEQAHLKPHLEKMLHSKPRGDDSNEEDGNVNDILDVKINENGSNLSVGQRQLLCLARALLNRSKILVLDEATASVDMETDKIIQDTI---RREFKDRTILTIAHRIDTVLDSDKIIVLDQGSVREFDSPSKLLSDKTS 1546

HSP 4 Score: 53.1434 bits (126), Expect = 3.493e-7
Identity = 48/193 (24.87%), Postives = 93/193 (48.19%), Query Frame = 2 
Query: 4109 GEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSV-LEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLE-TDDLIQSSIRRQ---FKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKE 4672
            G+ + +VGR GAGKS+   A+   +    G+     RD     L    S +    Q+  + + ++R N+  F    D + + + ++   L   +    +G + LV E G +LS GQK  + LARA+  ++ + +LD+  +AVD E + ++I+  +  +    K  T++   + ++ +     +  LE G + E
Sbjct:  665 GDLVCVVGRVGAGKSTFLKAILGQLPCMSGS-----RDSIPPKLIIRSSSVAYCSQESWIMNASVRENI-LFGHKFDQDYYDLTIKACQLLPDLKILPDGDETLVGEKGISLSGGQKARLSLARAVYSRADIYLLDDILSAVDAEVSKNIIEYVLIGKTALLKNKTIILTTNTVSILKHSQMIYALENGEIVE 851
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Yeast
Match: YBT1 (Transporter of the ATP-binding cassette (ABC) family; involved in bile acid transport; negative regulator of vacuole fusion; regulates release of lumenal Ca2+ stores; similar to mammalian bile transporters; YBT1 has a paralog, VMR1, that arose from the whole genome duplication [Source:SGD;Acc:S000003971])

HSP 1 Score: 412.92 bits (1060), Expect = 1.120e-119
Identity = 227/562 (40.39%), Postives = 342/562 (60.85%), Query Frame = 2 
Query: 3155 STNGTQNPDSQG----FYLGIYGSLGAGQALF---ILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKS--------------------------FIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAG 4741
            S    +N  S G    +YL +Y  +G  QAL      I NF        AS+ + N++L  +L +   FFD TP GRI+NR  KDI+ +D  +   I+    +    + ++ +I+  +P FL   + ++ +YY    FY+  SR+LKR +SI RSPIY HF E++VG ++IRA+     F+++     DEN   ++   V+ RWL F ++ IG+LVI  +G+  +   + + SG AG+S++YA+  T G  ++VR+ S++E +  +VER+KEY EIE E P+N  +      WP  G++E  + S+RY P L  V++N++  VDA  K+GIVGRTGAGKS++  ALFR +EP  G I IDN DI+ + L  LR  ITIIPQDP LFSGTI+ NLDP+++ SD +++  L+   L S                          F+  +SE     +SEGG NLS GQ+QL+CLAR+LL+  K+++LDEATA++D  +D  IQ +IR++F+  T+LTIAHRL +++DYD+++V++ G VKE D P +LL N++S F+SM   +G
Sbjct: 1087 SMASAENQPSSGHSTMYYLVLYLIIGFAQALLGAGKTILNFVAGIN---ASRKIFNMILNKVLHSKIRFFDATPTGRIMNRFSKDIEAIDQELTPYIQGAFYSLIECLSTVILITFITPQFLSVAIVVSILYYFVGYFYMAGSRELKRFESISRSPIYQHFSETLVGVTTIRAFGDEGRFMQENLHKIDENNKPFFYLWVANRWLAFRIDMIGSLVIFGAGLFILFNINNLDSGMAGISLTYAISFTEGALWLVRLYSEVEMNMNSVERVKEYMEIEQE-PYNEHKEIPPPQWPQDGKIEVNDLSLRYAPNLPRVIKNVSFSVDAQSKIGIVGRTGAGKSTIITALFRFLEPETGHIKIDNIDISGVDLQRLRRSITIIPQDPTLFSGTIKTNLDPYDEFSDRQIFEALKRVNLISEEQLQQGATRETSNEASSTNSENVNKFLDLSSE-----ISEGGSNLSQGQRQLMCLARSLLRSPKIILLDEATASIDYSSDAKIQETIRKEFQGSTILTIAHRLRSVIDYDKILVMDAGEVKEYDHPYSLLLNKQSAFYSMCEHSG 1639

HSP 2 Score: 304.294 bits (778), Expect = 2.776e-84
Identity = 173/477 (36.27%), Postives = 273/477 (57.23%), Query Frame = 2 
Query: 1337 RKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVE--VSPPDEKPVKIVDGTFSWGKTEAPV-LININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC----------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVI-GPSGLLSSKTRILVTHGLTY-LPKVDKIFVMKDGNVSESGTFTELLKNNGSFAE 2704
            +K++     S     +G I+NLM++D+ K+ ++  +LH    A +  V+A+  L++ LG + + GV +++ ++P+N  +   +  LQ K + + DNRI+ +NE    I+I+K ++WE +FE++I  IR +E  +L   + + ++S+  WF  P +V   +F A+ +     VLT   AF +LSLF +L  P+  L  ++ + +Q+ VSL R+  FL  +E DT+  +     P+       + T SW K      L ++N+E   G L  V+G  GSGKTSL+ AL+GE+Y ++G+V+                   SI Y  Q AW  N ++++NILF+ P    +Y  V+EAC L  D ++L AGD TEIGEKGI LSGGQKQR+SLARA+Y +    LLDD LSAVDSH    I+D  I GP  L+  +T ILV+H +   L   + + +++DG V + G   ++L+  G F E
Sbjct:  460 QKSINGDEESTSSANLGAIINLMAIDAFKVSEICGYLHSFLEAFVMTVVALALLYRLLGFAAIVGVLIIVAMLPLNYKLAKYIGDLQKKNLAVTDNRIQKLNEAFQAIRIIKYFSWEENFEKDINTIRENELSLLLMRSIVWSISSFLWFVTPTIVTAASF-AYYIYVQGEVLTTPVAFTALSLFTLLRDPLDRLSDMLSFVVQSKVSLDRVQDFL--NENDTKKYDQLTIDPNGNRFAFENSTISWDKDNQDFKLKDLNIEFKTGKLNVVIGPTGSGKTSLLMALLGEMYLLNGKVVVPALEPRQELIVDANGTTNSIAYCSQAAWLLNDTVKNNILFNSPFNEARYKAVVEACGLKRDFEILKAGDLTEIGEKGITLSGGQKQRVSLARALYSNARHVLLDDCLSAVDSHTASWIYDNCITGP--LMEDRTCILVSHNIALTLRNAELVVLLEDGRVKDQGDPIDMLQ-KGLFGE 930

HSP 3 Score: 79.7221 bits (195), Expect = 3.242e-15
Identity = 70/248 (28.23%), Postives = 122/248 (49.19%), Query Frame = 2 
Query: 4013 PDSGRVEFVNYSVRY-RPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIII---DNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNL---DPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLET-----DDLIQSSIRRQFKKCTVLTIAHRLN-TIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIF 4717
            P+  R  F N ++ + +   D  L++LNI    G+   ++G TG+GK+SL +AL   +    G +++   + R    +  +   + I    Q   L + T++ N+    PFN+       +V+E   LK        G    + E G  LS GQKQ V LARAL   ++ ++LD+  +AVD  T     D+ I   +    +  T + ++H +  T+ + + V++LE GRVK+   P ++L  +K +F
Sbjct:  689 PNGNRFAFENSTISWDKDNQDFKLKDLNIEFKTGKLNVVIGPTGSGKTSLLMALLGEMYLLNGKVVVPALEPRQELIVDANGTTNSIAYCSQAAWLLNDTVKNNILFNSPFNE---ARYKAVVEACGLKRDFEILKAGDLTEIGEKGITLSGGQKQRVSLARALYSNARHVLLDDCLSAVDSHTASWIYDNCITGPL---MEDRTCILVSHNIALTLRNAELVVLLEDGRVKDQGDPIDML--QKGLF 928

HSP 4 Score: 68.5514 bits (166), Expect = 9.058e-12
Identity = 114/516 (22.09%), Postives = 218/516 (42.25%), Query Frame = 2 
Query: 1289 YVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKL-QDVPSFLHVLWTAPI---TIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSF-EQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTA--FTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYG-IQAYV-SLKRINKFL-VGDELDTENVEVSPPD---EKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRV-------------MCRGSIGYIPQQAWCRNASLQDNI----LFSKPLINHKYNRV-------IEACALTEDLKVLPAGD----------QTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGS 2695
            +V G+ +   +  +I  K L         T  G I+N  S D + + Q++  ++   + + I   + VI I F+  +   SV   V+++   +    + GS+  +L+  +   +    +  +E L G+  ++ +  E  F ++N+  I  +     +   YL   +    F    + +L  F A  F L + +++   +     +SL   +SF    L  V +Y  ++  + S++R+ +++ +  E   E+ E+ PP    +  +++ D +  +      V+ N++  V   S + +VG  G+GK+++I+AL   L   +G +               R SI  IPQ     + +++ N+     FS   I     RV       ++  A  E      + +           +EI E G NLS GQ+Q + LAR++ +   + LLD+  +++D      I + +          T + + H L  +   DKI VM  G V E      LL N  S
Sbjct: 1127 FVAGINASRKIFNMILNKVLHSKIRFFDATPTGRIMNRFSKDIEAIDQELTPYIQGAFYSLIECLSTVILITFITPQF-LSVAIVVSILYYFVGYFYMAGSR--ELKRFESISRSPIYQHFSETLVGVTTIRAFGDEGRFMQENLHKIDENN----KPFFYLWVANRWLAFRIDMIGSLVIFGAGLFILFNINNL---DSGMAGISLTYAISFTEGALWLVRLYSEVEMNMNSVERVKEYMEIEQEPYNEHKEIPPPQWPQDGKIEVNDLSLRYAPNLPRVIKNVSFSVDAQSKIGIVGRTGAGKSTIITALFRFLEPETGHIKIDNIDISGVDLQRLRRSITIIPQDPTLFSGTIKTNLDPYDEFSDRQIFEALKRVNLISEEQLQQGATRETSNEASSTNSENVNKFLDLSSEISEGGSNLSQGQRQLMCLARSLLRSPKIILLDEATASIDYSSDAKIQETI---RKEFQGSTILTIAHRLRSVIDYDKILVMDAGEVKEYDHPYSLLLNKQS 1629
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Yeast
Match: VMR1 (Vacuolar membrane protein; involved in multiple drug resistance and metal sensitivity; ATP-binding cassette (ABC) family member involved in drug transport; potential Cdc28p substrate; induced under respiratory conditions; VMR1 has a paralog, YBT1, that arose from the whole genome duplication [Source:SGD;Acc:S000001027])

HSP 1 Score: 404.831 bits (1039), Expect = 3.566e-117
Identity = 218/549 (39.71%), Postives = 336/549 (61.20%), Query Frame = 2 
Query: 3152 GSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQA----HSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSF-----IAKTSE----------GLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAG 4741
            G T+ ++N  +  +YL +Y  +G  QA+    +          AS+ + N LL  +L A   FFD TP+GRI+NR  KDI+ VD  +   + + +         IF+I++ +P FL   V +  +Y+   ++Y+  SR+LKR+DSI +SPI+ HF E++VG  +IRA+     FI +     D+N  A++   V+ +W  F ++ IG  ++L SG   ++  + I SG AG+S++YA+  T G  ++VR+ S  E +  +VER+KEY+ IE E     +E +        WP  G +E  N S+RY P L  V+RN++  VD   K+GIVGRTGAGKS++  ALFRL+EP  G I ID +DI+K+ L  LR  ITIIPQDPILF+GTI+ N+DP++++ + +++  L    L S      +  + E           L   ++EGG NLS G++QL+ +AR+LL++ K+++LDEAT+++D ++D LIQ  IR +F K T+LTIAHRL +++DYDR++V++ G VKE D P  LL +E+ IF+SM  D+G
Sbjct: 1027 GMTDSSKNKHNAFYYLTVYFLIGIIQAMLGGFKTMMTFLSGMRASRKIFNNLLDLVLHAQIRFFDVTPVGRIMNRFSKDIEGVDQELIPYLEVTIFCLIQCASIIFLITVITPRFLTVAVIVFVLYFFVGKWYLTASRELKRLDSITKSPIFQHFSETLVGVCTIRAFGDERRFILENMNKIDQNNRAFFYLSVTVKWFSFRVDMIGAFIVLASGSFILLNIANIDSGLAGISLTYAILFTDGALWLVRLYSTFEMNMNSVERLKEYSSIEQENYLGHDEGRILLLNEPSWPKDGEIEIENLSLRYAPNLPPVIRNVSFKVDPQSKIGIVGRTGAGKSTIITALFRLLEPITGCIKIDGQDISKIDLVTLRRSITIIPQDPILFAGTIKSNVDPYDEYDEKKIFKALSQVNLISSHEFEEVLNSEERFNSTHNKFLNLHTEIAEGGLNLSQGERQLLFIARSLLREPKIILLDEATSSIDYDSDHLIQGIIRSEFNKSTILTIAHRLRSVIDYDRIIVMDAGEVKEYDRPSELLKDERGIFYSMCRDSG 1575

HSP 2 Score: 308.145 bits (788), Expect = 1.541e-85
Identity = 235/724 (32.46%), Postives = 361/724 (49.86%), Query Frame = 2 
Query:  674 QP--LLSLIPDDKTIPINR----IPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQIL-GLFITFIDNPN------DYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTG---MRSRTAVIGIIYRKAL--------KLSSTSRK-ETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPV----LININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVM-------------CRG---SIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVI-GPSGLLSSKTRILVTHGLTY-LPKVDKIFVMKDGNVSESGTFTELLKNNGSFAE 2704
            QP  L S I D+ +I   R     P  E+  S LS +T++W+T  + +  +  +  KD++ L   D    I+                           GFT   K + +                            ALF +    Y+L G+  V  + +    P IL   F+  +DNPN      +  W   L  I +F+  +  ++   Q   G +V+    +R R  +IG IY K L        K SS S      +G I+NL+S+DS K+ ++ ++L+V   A I I++ +  L+  LG S  AG+++++ + P+N ++ + + K Q + +K  D RI  +NE L  I+I+K +AWE +    I++IR  E R L   + + +V++  WF  P LV   TF   T       L A  AF +LSLF +L  P+  L  ++ +  Q+ VSLKRI+ FL  D+ +  N     PD+  ++  + T +W + ++ +    L  +N++   G L  ++G+ GSGK++L+  L+GEL  +SG ++             C G   S  Y  Q AW  N ++++NI+F       +YN+VI+AC L  DL++LPAGD TEIGEKGI LSGGQKQRISLARAVY      LLDD LSAVDSH    I++  I GP  L+ ++T ILVTH ++  L       V+++G V   GT TE L++ G F E
Sbjct:  242 QPIKLTSPIKDNSSIIYVRDDHTSPSREHISSILSCITWSWITNFIWEAQKNTIKLKDIWGLSMEDYSIFIL--------------------------KGFTRRNKHINN-------------------------LTLALFESFK-TYLLIGMLWVLVNSIVNLLPTILMKRFLEIVDNPNRSSSCMNLAW---LYIIGMFICRLTLAICNSQ---GQFVSDKICLRIRAILIGEIYAKGLRRRLFTSPKTSSDSDSISANLGTIINLISIDSFKVSELANYLYVTVQAVIMIIVVVGLLFNFLGVSAFAGISIILVMFPLNFLLANLLGKFQKQTLKCTDQRISKLNECLQNIRIVKYFAWERNIINEIKSIRQKELRSLLKKSLVWSVTSFLWFVTPTLVTGVTFAICTFVQHED-LNAPLAFTTLSLFTLLKTPLDQLSNMLSFINQSKVSLKRISDFLRMDDTEKYNQLTISPDKNKIEFKNATLTWNENDSDMNAFKLCGLNIKFQIGKLNLILGSTGSGKSALLLGLLGELNLISGSIIVPSLEPKHDLIPDCEGLTNSFAYCSQSAWLLNDTVKNNIIFDNFYNEDRYNKVIDACGLKRDLEILPAGDLTEIGEKGITLSGGQKQRISLARAVYSSAKHVLLDDCLSAVDSHTAVWIYENCITGP--LMKNRTCILVTHNVSLTLRNAHFAIVLENGKVKNQGTITE-LQSKGLFKE 903

HSP 3 Score: 81.6481 bits (200), Expect = 8.383e-16
Identity = 126/558 (22.58%), Postives = 237/558 (42.47%), Query Frame = 2 
Query: 1208 HGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKL-QDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIK-----LMNEILSGIKILKLYAWENSF-EQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNI-LSFPMSMLPGVIVYGIQAY----VSLKRINKFLVGDELDTENV------------EVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSG-------------RVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALT------EDLKVLPAGDQ------------TEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNN-GSFAEFIR 2713
            + F      FLI +I++++        +++GMR+   +   +    L         T VG I+N  S D + + Q++  +L V     I    +I FL   + P  L    ++  L    G    K     ++++K  D+  K       +E L G+  ++ +  E  F  +N+  I  +     R+  YL+    V WF   F V +    AF + +S   +  N A +   L  I L++ +    G + + ++ Y    +++  + +      ++ EN             E S P +  ++I + +  +     PV+ N++ +V   S + +VG  G+GK+++I+AL   L  ++G              V  R SI  IPQ       +++ N+    P   +   ++ +A +        E  +VL + ++            TEI E G+NLS G++Q + +AR++ ++  + LLD+  S++D +   H+   +I      +  T + + H L  +   D+I VM  G V E    +ELLK+  G F    R
Sbjct: 1037 NAFYYLTVYFLIGIIQAMLGGFKTMMTFLSGMRASRKIFNNLLDLVLHAQIRFFDVTPVGRIMNRFSKDIEGVDQELIPYLEVTIFCLIQCA-SIIFLITVITPRFLTVAVIVFVLYFFVG----KWYLTASRELKRLDSITKSPIFQHFSETLVGVCTIRAFGDERRFILENMNKIDQNN----RAFFYLSV--TVKWF--SFRVDM--IGAFIVLASGSFILLNIANIDSGLAGISLTYAILFTDGAL-WLVRLYSTFEMNMNSVERLKEYSSIEQENYLGHDEGRILLLNEPSWPKDGEIEIENLSLRYAPNLPPVIRNVSFKVDPQSKIGIVGRTGAGKSTIITALFRLLEPITGCIKIDGQDISKIDLVTLRRSITIIPQDPILFAGTIKSNV---DPYDEYDEKKIFKALSQVNLISSHEFEEVLNSEERFNSTHNKFLNLHTEIAEGGLNLSQGERQLLFIARSLLREPKIILLDEATSSID-YDSDHLIQGIIRSE--FNKSTILTIAHRLRSVIDYDRIIVMDAGEVKEYDRPSELLKDERGIFYSMCR 1572

HSP 4 Score: 65.4698 bits (158), Expect = 6.680e-11
Identity = 71/276 (25.72%), Postives = 128/276 (46.38%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLD----LVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHD---LRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLET-----DDLIQSSIRRQFKKCTVLTIAHRLN-TIMDYDRVMVLEQGRVK 4669
            L+ +  M S +    V+++RI ++  ++    +N       +  PD  ++EF N ++ +           L  LNI    G+   I+G TG+GKS+L L L   +    G+II+ + +     + D   L +      Q   L + T++ N+   N +++     V++   LK  +     G    + E G  LS GQKQ + LARA+   +K ++LD+  +AVD  T     ++ I   +    K  T + + H ++ T+ +    +VLE G+VK
Sbjct:  620 LDQLSNMLSFINQSKVSLKRISDFLRMDDTEKYN-----QLTISPDKNKIEFKNATLTWNENDSDMNAFKLCGLNIKFQIGKLNLILGSTGSGKSALLLGLLGELNLISGSIIVPSLEPKHDLIPDCEGLTNSFAYCSQSAWLLNDTVKNNIIFDNFYNEDRYNKVIDACGLKRDLEILPAGDLTEIGEKGITLSGGQKQRISLARAVYSSAKHVLLDDCLSAVDSHTAVWIYENCITGPL---MKNRTCILVTHNVSLTLRNAHFAIVLENGKVK 887
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Yeast
Match: YOR1 (Plasma membrane ATP-binding cassette (ABC) transporter; multidrug transporter mediates export of many different organic anions including oligomycin; homolog of human cystic fibrosis transmembrane receptor (CFTR) [Source:SGD;Acc:S000003513])

HSP 1 Score: 401.364 bits (1030), Expect = 1.656e-116
Identity = 226/603 (37.48%), Postives = 352/603 (58.37%), Query Frame = 2 
Query: 3008 IGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMC----CSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYA-EIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVL---------EMSYLKSFIAKTSEG----------LQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            +  +   ++  YI+++   + F  +  YA+ +     CS+ ++++LSYWTE    N    P S  FY+G+Y        +F+  +   L     +ASK L+   +K IL  P S+ DTTPLGRILNR  KD D++D  +  ++R+     + ++G   +  +  P+F +A+  L  ++ +    Y  + R++KR+++++RS +Y++  E + G  +I+AY+  + F+ K D + ++   A Y  +V  RW+  +L+ +     L+  +L V     I +   G+ ++Y LQ+ G LN ++R  +  E+   + ER+  YA E+  EA +   E      WP  G + F N    YRPGL +VL+NLN+ + +GEK+GI GRTGAGKS++  AL+RL E   G I+IDN DI++LGL DLR K+ IIPQDP+LF GTIR NLDPFN+ +D ELW  L         ++  +K  + K  E           L   V E G N S+G++QL+ L RAL+++SK+L+LDEAT++VD ETD  IQ+ I  +F  CT+L IAHRL TI++YDR++VLE+G V E D+P  L + E SIF SM   +G+
Sbjct:  873 VNSISLKIYREYIKAAVGKWGFIALPLYAILVVGTTFCSLFSSVWLSYWTENKFKN---RPPS--FYMGLYSFFVFAAFIFMNGQFTILCAMGIMASKWLNLRAVKRILHTPMSYIDTTPLGRILNRFTKDTDSLDNELTESLRLMTSQFANIVGVCVMCIVYLPWFAIAIPFLLVIFVLIADHYQSSGREIKRLEAVQRSFVYNNLNEVLGGMDTIKAYRSQERFLAKSDFLINKMNEAGYLVVVLQRWVGIFLDMVAIAFALIITLLCVTRAFPISAASVGVLLTYVLQLPGLLNTILRAMTQTENDMNSAERLVTYATELPLEASYRKPEMTPPESWPSMGEIIFENVDFAYRPGLPIVLKNLNLNIKSGEKIGICGRTGAGKSTIMSALYRLNELTAGKILIDNVDISQLGLFDLRRKLAIIPQDPVLFRGTIRKNLDPFNERTDDELWDALVRGGAIAKDDLPEVK--LQKPDENGTHGKMHKFHLDQAVEEEGSNFSLGERQLLALTRALVRQSKILILDEATSSVDYETDGKIQTRIVEEFGDCTILCIAHRLKTIVNYDRILVLEKGEVAEFDTPWTLFSQEDSIFRSMCSRSGI 1468

HSP 2 Score: 187.963 bits (476), Expect = 2.347e-48
Identity = 97/228 (42.54%), Postives = 143/228 (62.72%), Query Frame = 2 
Query: 2042 VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSI---GYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVM-KDGNVSESGTFTELLKNNGSFAEFIR 2713
            +K  DG     KT      ++N ++ +G  + + G +G+GK+SL++A+ G + K  G+V   G +   GY     W +NAS++DNI+F  P    KY+ V+  C+L  DL +LPAGD TEIGE+GI LSGGQK RI+LAR+VY+   +YL DD LSAVDS VGKHI D+ +  +G+L++KTRIL TH L+ + +  ++ V+  DG V + GT  EL   N +    ++
Sbjct:  587 LKDRDGPEDLEKTSFRGFKDLNFDIKKGEFIMITGPIGTGKSSLLNAMAGSMRKTDGKVEVNGDLLMCGY----PWIQNASVRDNIIFGSPFNKEKYDEVVRVCSLKADLDILPAGDMTEIGERGITLSGGQKARINLARSVYKKKDIYLFDDVLSAVDSRVGKHIMDECL--TGMLANKTRILATHQLSLIERASRVIVLGTDGQV-DIGTVDELKARNQTLINLLQ 807

HSP 3 Score: 122.094 bits (305), Expect = 3.687e-28
Identity = 120/478 (25.10%), Postives = 203/478 (42.47%), Query Frame = 2 
Query:  692 IPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNP----NDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMI-----CLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELD-TENVEVSP-PDEKP---VKIVDGTFSWGKTE 2083
            IP+       R   P    + +S + F W+  ++  GY++ +   DLF +    + +T+  + E     +N      K RKK  K++       P  +EEE  E             K    + LRAL  T    Y ++ VF +  +  +   P I    I F++      + +V  G   AI   L+  +  + F  ++H   +TG+++++ +     +K    S+ +R     G++ + ++ D  +++   SF   L   P  + I I  L   LGP  L G+ +        L     I+G ++    A  +   D R+ +M E+L+ IK++K Y WE+++E+NIQ+IR  E   +R                P + +L TF A    +       N  F SLSLF +LS  M  LP  I  GI   + L R+   L   E D  + +E+ P P   P   +K+   +F W   E
Sbjct:   95 IPEVPQTDDERKIYPLFHTNIISNMFFWWVLPILRVGYKRTIQPNDLFKMDPRMSIETLYDDFE-----KNMIYYFEKTRKKYRKRH-------PEATEEEVME-----------NAKLPKHTVLRALLFTFKKQYFMSIVFAILANCTSGFNPMITKRLIEFVEEKAIFHSMHVNKGIGYAIGACLMMFVNGLTFNHFFHTSQLTGVQAKSILTKAAMKKMFNASNYARHCFPNGKVTSFVTTDLARIEFALSFQPFLAGFPAILAICIVLLIVNLGPIALVGIGIFFGGFFISLFAFKLILGFRI----AANI-FTDARVTMMREVLNNIKMIKYYTWEDAYEKNIQDIRTKEISKVRKMQLSRNFLIAMAMSLPSIASLVTFLAMYKVNKGGRQPGN-IFASLSLFQVLSLQMFFLPIAIGTGIDMIIGLGRLQSLLEAPEDDPNQMIEMKPSPGFDPKLALKMTHCSFEWEDYE 543

HSP 4 Score: 72.7886 bits (177), Expect = 4.604e-13
Identity = 109/524 (20.80%), Postives = 214/524 (40.84%), Query Frame = 2 
Query: 1289 YVTGMRSRTAVIGIIYRKALKLSSTSR---------KETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAP------ITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAV---------SAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLV-GDELDTE----NVEVSPPDEKP----VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISAL--IGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNI-LFSKPLINHKYNRVIEACALTED----LKVLPAGDQTEIG------------EKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGT 2665
            ++ G  +    +GI+  K L L +  R           T +G I+N  + D+  L +  +    L T+       + ++  +Y  W  +    L  + + + +       G ++K+L+A Q     N    +NE+L G+  +K Y  +  F      + N     +  A YL  V           V    A  +  LC   AF +S++S         V + L  +L  P  +L  ++    Q    +    + +    EL  E      E++PP+  P    +   +  F++      VL N+N+ +  G  + + G  G+GK++++SAL  + EL   +G+++              R  +  IPQ       +++ N+  F++   +  ++ ++   A+ +D    +K+    +    G            E+G N S G++Q ++L RA+ +   + +LD+  S+VD      I  +++   G     T + + H L  +   D+I V++ G V+E  T
Sbjct:  948 FMNGQFTILCAMGIMASKWLNLRAVKRILHTPMSYIDTTPLGRILNRFTKDTDSLDNELTESLRLMTSQFANIVGVCVMCIVYLPWFAIAIPFL--LVIFVLIADHYQSSGREIKRLEAVQRSFVYNN---LNEVLGGMDTIKAYRSQERFLAKSDFLINK----MNEAGYLVVVLQRWVGIFLDMVAIAFALIITLLCVTRAFPISAAS---------VGVLLTYVLQLP-GLLNTILRAMTQTENDMNSAERLVTYATELPLEASYRKPEMTPPESWPSMGEIIFENVDFAYRPGLPIVLKNLNLNIKSGEKIGICGRTGAGKSTIMSALYRLNEL--TAGKILIDNVDISQLGLFDLRRKLAIIPQDPVLFRGTIRKNLDPFNERTDDELWDALVRGGAIAKDDLPEVKLQKPDENGTHGKMHKFHLDQAVEEEGSNFSLGERQLLALTRALVRQSKILILDEATSSVDYETDGKIQTRIVEEFG---DCTILCIAHRLKTIVNYDRILVLEKGEVAEFDT 1447

HSP 5 Score: 56.225 bits (134), Expect = 4.537e-8
Identity = 57/218 (26.15%), Postives = 95/218 (43.58%), Query Frame = 2 
Query: 4079 LRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNL---DPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLET-DDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVL------EQGRVKEIDSPQNLLAN 4702
             ++LN  +  GE + I G  G GKSSL  A+   +   +G + + N D+   G              P + + ++R N+    PFN+    E   V+ +  LK+ +     G    + E G  LS GQK  + LAR++ KK  + + D+  +AVD      ++   +       T +   H+L+ I    RV+VL      + G V E+ +    L N
Sbjct:  604 FKDLNFDIKKGEFIMITGPIGTGKSSLLNAMAGSMRKTDGKVEV-NGDLLMCGY-------------PWIQNASVRDNIIFGSPFNKEKYDE---VVRVCSLKADLDILPAGDMTEIGERGITLSGGQKARINLARSVYKKKDIYLFDDVLSAVDSRVGKHIMDECLTGMLANKTRILATHQLSLIERASRVIVLGTDGQVDIGTVDELKARNQTLIN 804
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Nematostella
Match: EDO36474 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SII0])

HSP 1 Score: 616.305 bits (1588), Expect = 0.000e+0
Identity = 290/558 (51.97%), Postives = 409/558 (73.30%), Query Frame = 2 
Query: 1055 PSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDE---KPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            PS ++ LF      + LA  FK+  D ++F QP IL L I+F++  N   W G++ A+ +F  +  +S++   Y+H     G++ +TA+ G+IY KAL+L+S SR ++T G++VNLMSVD+Q++ D+ +++++LW+ P+ IV+A+YFL+  +G S++AGV +M+ LIP N ++    +KLQ KQM  KD+RI++MNEIL+G+K+LKLYAWE SF   +  IRN E   L++A YLNA    T+ CAPFLV+L TF  + L+   ++LTAN AFV++SLFNIL FP+++LP VI+  +QA VSLKR+ KFL  DELD  NV    P     + + + DG+FSW  T  P L NIN+ +P+GSLVAVVG VG GK++L+SAL+GE  KV+G V  +GS+ Y+PQQAW +NA+L+DN++F +   + +Y++ I+ CAL  D  +LPAGD TEIGE+GINLSGGQKQR++LARAVY +  VYLLDDPLSAVDSHVGKHIFD+VIGP G L  KTR+LVTHG+++LP+VD+I V++DG VSE GT+ ELL N G+FAEF++T+
Sbjct:    2 PSLMKVLFLIFWPQFFLAAFFKLIQDSMSFVQPTILRLMISFVEG-NSPSWEGYMYALIMFAAAAFQSILLHAYFHIVISAGIKIKTALTGLIYSKALRLNSVSRNKSTAGDMVNLMSVDAQRVLDMCTYINLLWSGPLQIVVALYFLYDTMGWSIVAGVVVMVLLIPFNLVVTRFSRKLQLKQMANKDSRIRIMNEILNGMKVLKLYAWEESFMAKVTGIRNQELHHLKNAMYLNAFFGFTFTCAPFLVSLATFAIYVLTG--NILTANNAFVAISLFNILRFPLTVLPNVIISYVQAQVSLKRLTKFLTLDELDETNVHKKMPSHISNQAIHVDDGSFSWDVTGQPTLHNINLNIPDGSLVAVVGQVGCGKSTLLSALLGETEKVTGEVYVKGSVAYVPQQAWIQNATLRDNVIFGRNFDSRRYHKTIKVCALETDFDILPAGDMTEIGERGINLSGGQKQRVNLARAVYFNADVYLLDDPLSAVDSHVGKHIFDKVIGPRGKLRKKTRVLVTHGISFLPQVDQIVVLQDGRVSEVGTYKELLANRGAFAEFLKTF 556

HSP 2 Score: 598.586 bits (1542), Expect = 0.000e+0
Identity = 306/582 (52.58%), Postives = 423/582 (72.68%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            A  G VK+ VF +Y +S     +  V+    L     VG+ ++L+ W+    T+      ++  YLG Y + G  QA F+L+ +  LA+G+  AS+S+H+ LL  I  AP SFF+TTPLGR++NR  KD+  VD ++P +   +L TA   IG++F I+ ++P FL  ++PL  +Y + QR Y+ +SRQLKRI+S+ +SPIY++F E+I G S+IRAY     FI+      DENQ+A+YP +VS RWL   LE +GNL+I  + + AVV R +I S   G+SI+YALQIT  LN MVR TS+LE++ V+VER KEYA++E+EA W +E+S+    WPD GR++  ++ +RYR  L LVL+N+++ +  GEK+GIVGRTGAGKS+L LALFR++E A G I++D+ DI+K+GL DLRS +TIIPQDP+LFSGT+R NLDPF+ +SD +LW VLE+S+LK+F +   EGL + ++EGGENLSVGQ+QLVCLARALL+KSKVLVLDEATAAVDLETD+LIQ++IR +F + TV TIAHRLNTIMDY R++VL++G + E DSPQNL+A ++ IF+ MA DAGLA
Sbjct:  646 AATGSVKWVVFWAYAKSIGVFIASIVILFMILSEGALVGSRIWLAAWSADNDTSDA----TRDMYLGGYAAFGFFQAFFVLVSSICLAFGSVRASRSIHDSLLIAIFHAPMSFFETTPLGRVVNRFSKDLYVVDDTVPRSTSGFLRTALSAIGTLFAITYATPLFLSVIIPLGIVYVLIQRLYVASSRQLKRIESVSKSPIYNNFFETISGTSTIRAYHQQQRFIRGNYYKVDENQLAYYPLVVSNRWLGLRLEFVGNLIIFFAALFAVVGRDSIESALVGMSITYALQITQTLNMMVRQTSELETNIVSVERTKEYADMETEAEWVVEDSRPPKGWPDKGRIQIEDFDLRYRANLPLVLKNISVDIQPGEKIGIVGRTGAGKSTLTLALFRILESAGGRIVVDDLDISKMGLQDLRSSLTIIPQDPVLFSGTLRFNLDPFDAYSDEDLWEVLEVSHLKAFASGLPEGLLHPIAEGGENLSVGQRQLVCLARALLRKSKVLVLDEATAAVDLETDELIQNTIRTEFAERTVFTIAHRLNTIMDYSRILVLDKGFMMEFDSPQNLIA-QRGIFYGMAQDAGLA 1222

HSP 3 Score: 80.1073 bits (196), Expect = 6.503e-15
Identity = 60/215 (27.91%), Postives = 106/215 (49.30%), Query Frame = 2 
Query: 4079 LRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELW-SVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKS 4711
            L N+N+ +  G  + +VG+ G GKS+L  AL    E   G + +             +  +  +PQ   + + T+R N+  F ++ D   +   +++  L++       G    + E G NLS GQKQ V LARA+   + V +LD+  +AVD      I   +   R + +K T + + H ++ +   D+++VL+ GRV E+ + + LLAN  +
Sbjct:  348 LHNINLNIPDGSLVAVVGQVGCGKSTLLSALLGETEKVTGEVYV-------------KGSVAYVPQQAWIQNATLRDNV-IFGRNFDSRRYHKTIKVCALETDFDILPAGDMTEIGERGINLSGGQKQRVNLARAVYFNADVYLLDDPLSAVDSHVGKHIFDKVIGPRGKLRKKTRVLVTHGISFLPQVDQIVVLQDGRVSEVGTYKELLANRGA 548

HSP 4 Score: 77.411 bits (189), Expect = 4.214e-14
Identity = 63/237 (26.58%), Postives = 104/237 (43.88%), Query Frame = 2 
Query: 2027 PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            PD+  ++I D    +      VL NI++++  G  + +VG  G+GK++L  AL   L    GR++              R S+  IPQ     + +L+ N+       +     V+E   L      LP G    I E G NLS GQ+Q + LARA+ +   V +LD+  +AVD    + I + +       + +T   + H L  +    +I V+  G + E  +   L+   G F
Sbjct:  979 PDKGRIQIEDFDLRYRANLPLVLKNISVDIQPGEKIGIVGRTGAGKSTLTLALFRILESAGGRIVVDDLDISKMGLQDLRSSLTIIPQDPVLFSGTLRFNLDPFDAYSDEDLWEVLEVSHLKAFASGLPEGLLHPIAEGGENLSVGQRQLVCLARALLRKSKVLVLDEATAAVDLETDELIQNTI---RTEFAERTVFTIAHRLNTIMDYSRILVLDKGFMMEFDSPQNLIAQRGIF 1212
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Nematostella
Match: EDO35071 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMJ8])

HSP 1 Score: 552.362 bits (1422), Expect = 1.798e-174
Identity = 268/528 (50.76%), Postives = 379/528 (71.78%), Query Frame = 2 
Query: 1157 ILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRI---KLMNEILSG-IKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDE---KPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            ++ L I+F++  N   W G++ A+ +F  +  +S++   Y+H     G++ +TA+ G+IY KAL+L+S SR ++T G++VNLMSVD+Q++ D+ +++++LW+ P+ IV+A+YFL+  +G S++AGV +M+ LIP N ++    +KLQ  Q  +    +    L    L G  K+LKLYAWE SF   +  IRN E   L++A YLNA    T+ CAPFLV+L TF  + L+   ++LTAN AFV++SLFNIL FP+++LP VI+  +QA VSLKR+ KFL  DELD  NV    P     + + + DG+FSW  T  P L NIN+ +PEGSLVAVVG VG GK++L+SAL+GE  KV+G V  +GS+ Y+PQQAW +NA+L+DN++F +   + +Y++ I+ CAL  D  +LPAGD TEIGE+GINLSGGQKQR++LARAVY +  VYLLDDPLSAVDSHVGKHIFD+VIGP G L  KTR+LVTHG+++LP+VD+I V++DG VSE GT+ ELL N G+FAEF++T+
Sbjct:    1 LIRLMISFVEG-NSPSWEGYMYALIMFAAAAFQSILLHAYFHIVISAGIKIKTALTGLIYSKALRLNSVSRNKSTAGDMVNLMSVDAQRVLDMCTYINLLWSGPLQIVVALYFLYDTMGWSIVAGVVVMVLLIPFNLVVTRFSRKLQVCQFILIGVSLCQPPLCRCCLWGSCKVLKLYAWEESFMAKVTGIRNQELHHLKNAMYLNAFFGFTFTCAPFLVSLATFAIYVLTG--NILTANNAFVAISLFNILRFPLTVLPNVIISYVQAQVSLKRLTKFLTLDELDETNVHKKMPSHISNQAIHVDDGSFSWDVTGQPTLHNINLNIPEGSLVAVVGQVGCGKSTLLSALLGETEKVTGEVYVKGSVAYVPQQAWIQNATLRDNVIFGRNFDSRRYHKTIKVCALETDFDILPAGDMTEIGERGINLSGGQKQRVNLARAVYFNADVYLLDDPLSAVDSHVGKHIFDKVIGPRGKLRKKTRVLVTHGISFLPQVDQIVVLQDGRVSEVGTYKELLANRGAFAEFLKTF 525

HSP 2 Score: 373.629 bits (958), Expect = 1.825e-109
Identity = 196/420 (46.67%), Postives = 286/420 (68.10%), Query Frame = 2 
Query: 3017 VKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQ 4276
            VK+ VF +Y +S     +  V+    L     VG+ ++L+ W+    T+      ++  YLG Y + G  QA F+L+ +  LA+G+  AS+S+H+ LL  I  AP SFF+TTPLGR++NR  KD+  VD ++P +   +L TA   IG++F I+ ++P FL  ++PL  +Y + QR Y+ +SRQLKRI+S+ +SPIY++F E+I G S+IRAY     FI+      DENQ+A+YP +VS RWL   LE +GNL+I  + + AVV R +I S   G+SI+YALQIT  LN MVR TS+LE++ V+VER KEYA++E+EA W +E+S+    WPD GR++  ++ +RYR  L LVL+N+++ +  GEK+GIVGRTGAGKS+L LALFR++E A G I++D+ DI+++GL DLRS +TIIPQ
Sbjct:  626 VKWVVFWTYAKSIGVFIASIVILFMILSEGALVGSRIWLAAWSADNDTSDA----TRDMYLGGYAAFGFFQAFFVLVSSICLAFGSVRASRSIHDSLLIAIFHAPMSFFETTPLGRVVNRFSKDLYVVDDTVPRSTSGFLRTALSAIGTLFAITYATPLFLSVIIPLGIVYVLIQRLYVASSRQLKRIESVSKSPIYNNFFETISGTSTIRAYHQQQRFIRGNYYKVDENQLAYYPLVVSNRWLGLRLEFVGNLIIFFAALFAVVGRDSIESALVGMSITYALQITQTLNMMVRQTSELETNIVSVERTKEYADMETEAEWVVEDSRPPKGWPDKGRIQIEDFDLRYRANLPLVLKNISVDIQPGEKIGIVGRTGAGKSTLTLALFRILESAGGRIVVDDLDISRMGLQDLRSSLTIIPQ 1041

HSP 3 Score: 81.2629 bits (199), Expect = 2.830e-15
Identity = 60/213 (28.17%), Postives = 105/213 (49.30%), Query Frame = 2 
Query: 4079 LRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELW-SVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            L N+N+ +  G  + +VG+ G GKS+L  AL    E   G + +             +  +  +PQ   + + T+R N+  F ++ D   +   +++  L++       G    + E G NLS GQKQ V LARA+   + V +LD+  +AVD      I   +   R + +K T + + H ++ +   D+++VL+ GRV E+ + + LLAN 
Sbjct:  317 LHNINLNIPEGSLVAVVGQVGCGKSTLLSALLGETEKVTGEVYV-------------KGSVAYVPQQAWIQNATLRDNV-IFGRNFDSRRYHKTIKVCALETDFDILPAGDMTEIGERGINLSGGQKQRVNLARAVYFNADVYLLDDPLSAVDSHVGKHIFDKVIGPRGKLRKKTRVLVTHGISFLPQVDQIVVLQDGRVSEVGTYKELLANR 515
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Nematostella
Match: EDO43433 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYB6])

HSP 1 Score: 471.47 bits (1212), Expect = 9.374e-153
Identity = 228/401 (56.86%), Postives = 298/401 (74.31%), Query Frame = 2 
Query: 3542 RFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            R ++ TSRQLKR++S+ RSPIYSHF ESI G + IRA++    F+++ +   D  QMA YP++   RWL   LE +G  V+L + + AVV+R  I  G  GLS++YALQITG L ++VR +S+LE++ VAVERIKEY+E  +EA W I   +  +DWP  G V   +  +RYR     V++ L   +++GEK+GIVGRTGAGKS+L+LALFR++E A G I+IDN DI K+GL DLRS++TIIPQD +LFSG++++NLDPF    D ELW VLE  +LKSF++   +GL + + EGGENLS GQ QLVCLARALL+KSKVLVLDEATAAVDLETD+LIQ++IR +F   TVLTIAHRLNTIMDY R+MVL++G + E D+P  LLA +K +FH MA DAGL
Sbjct:    1 RLFVSTSRQLKRLESVSRSPIYSHFYESITGCTIIRAFRQQRRFVQESNSKVDHAQMANYPSLCINRWLSLRLELLGAAVLLFAALFAVVSRGRIAPGLVGLSVAYALQITGVLTWLVRQSSELETNIVAVERIKEYSETPTEAAWVIPGRRPPADWPQEGHVAVESLDMRYRDDQPPVIKKLTFEINSGEKIGIVGRTGAGKSTLSLALFRILERASGKIVIDNIDINKIGLQDLRSRLTIIPQDAVLFSGSVKLNLDPFESTCDEELWRVLEAVHLKSFVSSLQDGLMHQIQEGGENLSAGQCQLVCLARALLRKSKVLVLDEATAAVDLETDELIQNTIRTEFADRTVLTIAHRLNTIMDYTRIMVLDEGSILEFDTPSALLA-QKGVFHEMAKDAGL 400

HSP 2 Score: 88.5817 bits (218), Expect = 3.076e-18
Identity = 73/274 (26.64%), Postives = 125/274 (45.62%), Query Frame = 2 
Query: 1955 VSLKRINKFLVGDELDTENVEVSP--------PDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIR 2713
            V+++RI ++    E  TE   V P        P E  V +      +   + PV+  +  E+  G  + +VG  G+GK++L  AL   L + SG+++              R  +  IPQ A   + S++ N+   +   + +  RV+EA  L   +  L  G   +I E G NLS GQ Q + LARA+ +   V +LD+  +AVD    + I + +       + +T + + H L  +    +I V+ +G++ E  T + LL   G F E  +
Sbjct:  129 VAVERIKEY---SETPTEAAWVIPGRRPPADWPQEGHVAVESLDMRYRDDQPPVIKKLTFEINSGEKIGIVGRTGAGKSTLSLALFRILERASGKIVIDNIDINKIGLQDLRSRLTIIPQDAVLFSGSVKLNLDPFESTCDEELWRVLEAVHLKSFVSSLQDGLMHQIQEGGENLSAGQCQLVCLARALLRKSKVLVLDEATAAVDLETDELIQNTI---RTEFADRTVLTIAHRLNTIMDYTRIMVLDEGSILEFDTPSALLAQKGVFHEMAK 396
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Nematostella
Match: EDO31647 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXB5])

HSP 1 Score: 472.626 bits (1215), Expect = 3.328e-142
Identity = 245/583 (42.02%), Postives = 361/583 (61.92%), Query Frame = 2 
Query: 3011 GGVKFSVFLSYIRSSTYLFS---FTVVFSYALYMCCSVGANMF----LSYWTETGSTNGT---QNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEY-AEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSM 4726
            G V+ S +++Y++S+  +F+     + F   L+M   +    F    L YW + G+  G    ++ D   +Y+ +YG         +L++ F     T  AS  LH+L  K ++    SFFD TP GRILNR  KD+D VD  +P T+  ++     +  ++ ++S   PYFL+A+VPL   +++   ++  + R+LKR+D I RSPI+SH   ++ G S++ A+    DF  +   + D N + ++   VS RWL   L+ I  ++  ++ +L V T+  +   +AGL++SYA++ITG   + VRM ++ ES   +VERI  Y   + SEAP  I E++   +WP  G + F    +RYR GL LVL NL   V   EK+GIVGRTG+GKSS+ + L+RL+E + G+I IDN DI+ LGL DLRSKI+IIPQDP+LF+GTIR NLDPF ++SD ELW  LE S+LK  ++     L+  V E GEN SVG++QL+C+ARALL+ SK+L++DEATAA+D ETD  IQ +IR  F  CTVLTIAHRLNT++  DR+MV+E G++ E D P  L A+ +S F  +
Sbjct:  745 GAVRLSTYVNYMKSAGGMFAQPCVCISFMLVLFMLACLLLQTFVDSWLGYWLDAGNKTGIIEHEDGDINNYYMMVYGVCALVFLFGLLLKTFMFVKFTLKASSKLHDLCFKKVMSGTMSFFDVTPTGRILNRFSKDLDEVDAQLPWTLESFMQNVLRIFIALGLVSAMFPYFLIAVVPLMIFFFVLNSYFRRSVRELKRLDGITRSPIFSHLTATVQGLSTLHAFDKMADFNARFSSLIDLNTLPFFMYFVSNRWLSVRLDIITVVITTVTALLVVTTKGVLTEAFAGLALSYAIRITGLFQFTVRMAAETESRFTSVERINYYITSVPSEAPAEIPETKTKDEWPQEGTIVFNQVKMRYRSGLPLVLDNLTGFVRPQEKIGIVGRTGSGKSSVGVVLWRLVELSGGSIKIDNIDISTLGLQDLRSKISIIPQDPVLFAGTIRFNLDPFRKYSDEELWKALERSHLKDMVSNLPLKLEAPVVENGENFSVGERQLICMARALLRHSKILMMDEATAAIDSETDAKIQDTIRDAFVDCTVLTIAHRLNTVLTADRIMVMEAGKIVEFDEPSVLSADPESYFSKL 1327

HSP 2 Score: 286.96 bits (733), Expect = 6.951e-79
Identity = 219/733 (29.88%), Postives = 343/733 (46.79%), Query Frame = 2 
Query:  773 TWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRV--KQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRAL--FHTIGYPYMLAG-VFKVAYDLLTFAQPQILGLFITFI-----DNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKP------VKIVDGTFSWGKTE-------------------------------APV-LININMEVPEGSLVAVVGTVGSG------KTSLISALI--------GELYKVSGRV--------MC--------RGSIG------YIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELL--KNNGSFAEFIR 2713
            +W + +V KG+R+PL   DL  L + +T +   T ++  W+ E   V  K  +  K L         ++ +++      I FV +            +FL  +  F     P +L   VF+               LFI +I           + +G  L + L L  ++R       +     TG R+R+ V  +IY+K  KL +   K  ++GE VNL + D+Q++ +  S        P+ I++AI +    +GPS L G  L++ + PI   +     +L+ K +++ D R+++M+E+L+ IK++K+YAW+ SF  NI   R +E   L SA  L  ++       P +  + +F+     ++   LT+ +AF  +++FN+L F +++LP  +    +A  +L R+   +  +EL       SP  +KP      + I    FSW K                                  P+ L  I +         +  T G G      KT L+ +L         G L  + G V         C        +G +G      Y+ QQAW  NA+ +DNIL   P    +Y     AC+LT+D ++LP GDQTEIGE+GINLSGGQKQRISLARA+Y D  +YLLDDPLSAVD+HVG+HIF   I   G L  K+ +  TH L YL + D++  M +G ++E GT+ +L+  K N +F E  R
Sbjct:    2 SWASPIVYKGFRKPLQMDDLGELSQYETIEVNGTRIKRIWDEEVDTVGLKHARLGKVL---------WRCVRTRLIMGMIMFVISQMI---------TFLGPVRFFSNGDTPCLLCSCVFQ--------------ALFIRYILEYLAKQNTTSLGYGIALVMGLLLTEILRVAFLSFSFFLNIRTGTRARSMVYSLIYQKLSKLRNVGDK--SIGEFVNLCASDAQRIYEGVSIGCFSLGGPVVIIMAIIYTTYLIGPSALVGCGLVLLVFPIQMKVARLAGQLRGKVVRITDQRVRMMSEVLNCIKLIKMYAWDRSFADNIVAKRTEERNALTSAGLLQGINMSIALIIPTVATVASFSVHI--ATGQNLTSAQAFTIMTIFNVLVFSLAVLPFGVRAVAEASTALTRVKSLMQMEEL-------SPFLDKPSNSNVALSIEHCDFSWDKVSLLYKSDGFNGQTASDGKVKQAKSQKQYIPSLGPIQLPCIRLCYCHNQTTRLPSTSGRGGPILPVKTKLVPSLFDIDLEVKKGSLIGICGSVGSGKSSLLQCILSQMRKTKGRVGIGGSIAYVSQQAWIMNATAKDNILLGLPFNESRYKAACFACSLTKDFEILPNGDQTEIGERGINLSGGQKQRISLARALYADKDLYLLDDPLSAVDAHVGQHIFKHCI--KGSLWGKSVLFATHQLQYLSQCDQVLYMNNGRIAERGTYIQLIQDKKNPNFTEIHR 689

HSP 3 Score: 64.6994 bits (156), Expect = 3.468e-10
Identity = 62/258 (24.03%), Postives = 112/258 (43.41%), Query Frame = 2 
Query: 1952 YVSLKRINKFL--VGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAP-------VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVM--------------CRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSE 2656
            + S++RIN ++  V  E   E  E    DE P    +GT  + + +         VL N+   V     + +VG  GSGK+S +  ++  L ++SG  +               R  I  IPQ       +++ N+   +   + +  + +E   L + +  LP   +  + E G N S G++Q I +ARA+ +   + ++D+  +A+DS     I D +          T + + H L  +   D+I VM+ G + E
Sbjct: 1059 FTSVERINYYITSVPSEAPAEIPETKTKDEWPQ---EGTIVFNQVKMRYRSGLPLVLDNLTGFVRPQEKIGIVGRTGSGKSS-VGVVLWRLVELSGGSIKIDNIDISTLGLQDLRSKISIIPQDPVLFAGTIRFNLDPFRKYSDEELWKALERSHLKDMVSNLPLKLEAPVVENGENFSVGERQLICMARALLRHSKILMMDEATAAIDSETDAKIQDTI---RDAFVDCTVLTIAHRLNTVLTADRIMVMEAGKIVE 1309

HSP 4 Score: 63.929 bits (154), Expect = 4.986e-10
Identity = 57/215 (26.51%), Postives = 95/215 (44.19%), Query Frame = 2 
Query: 4079 LRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLD---PFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLET-DDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKS 4711
            L ++++ V  G  +GI G  G+GKSSL   +   +   +G + I                I  + Q   + + T + N+    PFN+       +    S  K F      G Q  + E G NLS GQKQ + LARAL     + +LD+  +AVD      + +  I+      +VL   H+L  +   D+V+ +  GR+ E  +   L+ ++K+
Sbjct:  483 LFDIDLEVKKGSLIGICGSVGSGKSSLLQCILSQMRKTKGRVGIGG-------------SIAYVSQQAWIMNATAKDNILLGLPFNESRYKA--ACFACSLTKDF-EILPNGDQTEIGERGINLSGGQKQRISLARALYADKDLYLLDDPLSAVDAHVGQHIFKHCIKGSLWGKSVLFATHQLQYLSQCDQVLYMNNGRIAERGTYIQLIQDKKN 681
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Nematostella
Match: EDO35250 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM18])

HSP 1 Score: 441.039 bits (1133), Expect = 1.230e-136
Identity = 227/551 (41.20%), Postives = 340/551 (61.71%), Query Frame = 2 
Query: 3122 NMFLSYWTET-------GSTNG--TQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGV--LAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAG 4741
            + +L++W++          T+G  TQ+P  + +Y+ +YG L     L   I +F   Y    ASK+LHN +   +LRAP  FFDT P GRI+NR  KDI  +D  +P T   ++  A      + V   + P+ ++ ++PL   +   + +Y+ TSR++KRI++I R+PI++HF  ++ G ++IR+         +     D +  AW+  I + RWL   LE +  L + ++    L +     I +G  GL++SYA+ +TG   + VRM++++E+   AVER+ +Y+++E E  W+ E S     WP  G +   + S++Y   L  VL+N+   V   EK+GIVGRTG GKSSL  AL RL+EP +G + ID  DIT +GLHDLRSKI++IPQDP+LFSG++R NLDP +Q+ D ELW+ L+   L   + +  +GL   V+E G N SVGQ+QL+CLARALL+++ +L++DEATA VD  TD LIQ +IR +FK CTVLTIAHRLNTIMD DRVMVL+ G++ E + P  +L N +S+F  +  + G
Sbjct:  192 DWWLAHWSDIDYKQNLLNETSGIVTQSPYDRRYYIAVYGGLVLLTFLLSFIRSFLFFYVKVAASKALHNKMFCAVLRAPMYFFDTNPAGRIINRFSKDIGFMDDLLPETFYEFISLAILCFAVVVVNVATMPWVIIGILPLAVAFLFVRSYYLKTSREVKRIEAIGRTPIFNHFSSTLEGLATIRSLSSQTQVTAELAACQDHHSEAWFLFIATSRWLAIRLEMLCLLFVTMAAFTPLFLSRNHDIDAGVVGLTLSYAVMLTGMFQWCVRMSAEVENQMTAVERVVDYSKVEPEGEWHKECSDVPPIWPVHGLITAESLSLQYHATLPRVLKNMCFCVRPKEKVGIVGRTGTGKSSLLAALIRLVEP-KGIMRIDGVDITDIGLHDLRSKISVIPQDPVLFSGSLRHNLDPVSQYKDEELWTALKEVQLGDAVLEFPDGLDTKVTESGNNFSVGQRQLICLARALLRRNVILIIDEATAHVDQRTDALIQKTIRSKFKDCTVLTIAHRLNTIMDMDRVMVLDNGKLVEFEEPFVMLLNPESVFSKLVAETG 741

HSP 2 Score: 88.1965 bits (217), Expect = 1.401e-17
Identity = 45/89 (50.56%), Postives = 57/89 (64.04%), Query Frame = 2 
Query: 2450 RAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRT 2716
            RAVY +  VYLLDDPLS+VD+HVG+H+FD  I   GL+    RILVTH L YL    +I  +K+G V   GT+TEL  +   F   I+T
Sbjct:    1 RAVYYNADVYLLDDPLSSVDTHVGRHLFDACI--CGLIKDCPRILVTHQLQYLHSATEILCLKEGRVLGIGTYTELTTSGIDFTTLIKT 87

HSP 3 Score: 63.1586 bits (152), Expect = 8.478e-10
Identity = 57/223 (25.56%), Postives = 100/223 (44.84%), Query Frame = 2 
Query: 2090 VLININMEVPEGSLVAVVGTVGSGKTSLISALI-----GELYKVSGRVMC-------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRV---IEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSE-SGTFTELLKNNGSFAEFI 2710
            VL N+   V     V +VG  G+GK+SL++ALI       + ++ G  +        R  I  IPQ     + SL+ N+    P+  +K   +   ++   L + +   P G  T++ E G N S GQ+Q I LARA+ +   + ++D+  + VD      I   +          T + + H L  +  +D++ V+ +G + E    F  LL     F++ +
Sbjct:  521 VLKNMCFCVRPKEKVGIVGRTGTGKSSLLAALIRLVEPKGIMRIDGVDITDIGLHDLRSKISVIPQDPVLFSGSLRHNL---DPVSQYKDEELWTALKEVQLGDAVLEFPDGLDTKVTESGNNFSVGQRQLICLARALLRRNVILIIDEATAHVDQRTDALIQKTI---RSKFKDCTVLTIAHRLNTIMDMDRVMVLDNGKLVEFEEPFVMLLNPESVFSKLV 737
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Medaka
Match: abcc1 (multidrug resistance-associated protein 1 [Source:NCBI gene;Acc:101173789])

HSP 1 Score: 757.673 bits (1955), Expect = 0.000e+0
Identity = 411/918 (44.77%), Postives = 585/918 (63.73%), Query Frame = 2 
Query:   26 MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRG-----KFNIFKSTLIAFIL--------FFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLL-ASITVIYSRYRRLKFHDR----DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKP--VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            MG   F   CS  S++   W     WNT +PD+T CFQ T+L W+P L+LW+    Y+  + +       NRG       N  K T + F+L        F+       + + +  +L  P  L L    + + + LL+   R+   KG+ SSG++  +WLL LL AS+T    R + L+  D+      +R  T    + L+ ++ +L+C +D                     PL S    D        PCPE   SFLS++TF W++G+++ GY++PL  KDL++L   D    +V  +  +W  E  +VK+T      E++  ++    P    +E   ++  +       +K + PS L AL  T    ++++ ++K+  D+L F  P+IL L I F+++P+   W G+  A  LF+ + ++S+I Q+Y+H C+V+GMR RTAVIG IYRKAL +SS +R+ +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +V+A+YFLW+ LGPSVLAGVA+MI ++PIN +I  K K  Q  QMK KD+RIKLMNE+L+GIK+LKLYAWE +F++ +  IR +E ++L+ A YL AVS  TW CAPFLVAL TF+ + L    +VL A KAFVSL+LFNIL FP++MLP VI   +QA VSLKR+  FL  +EL  ++VE       P  + I DG FSW ++E+P L  +N+ +PEGSLVAVVG VGSGK+SL+SAL+GE+ K+ G V  +GS+ Y+PQQAW  NA+L++NI+F +      Y+RV+EACAL +DL++LPAGD+TEIGEKG+NLSGGQKQR+SLARAVY D SVYLLDDPLSAVD+HVGKHIFD VIGP GLL  KTRILVTHGL+YLP+   + VM DG ++E G++ +L +  G+FAEF+R Y
Sbjct:    1 MGLDRF---CSPNSSE-PFWDWNRSWNTSNPDLTPCFQSTVLVWVPCLYLWLCAPFYLMYMRS------HNRGYICMSHLNKAK-TAVGFLLWIICWLDVFYSFWERSHSRNVAAVHLVSPTLLGL----TMLLATLLVQYERM---KGVQSSGIMLIFWLLALLCASVTF---RSKILQAQDQPEAVSGWRYTTFYVYYALLLLALVLSCLSD-------------------QMPLFSQAVKDPN------PCPEPGASFLSRITFWWISGMMLSGYKRPLEEKDLWSLNPEDRSHCVVPQLLRRWTAECHKVKRT------EEKMLYSPKQPPHGENKEVRAVEESEILIVKSPKKSREPSLLWALCLTFAPHFLVSCLYKLIQDILMFVGPEILRLLILFVNDPDAPSWQGYFYAALLFVCTCVQSLILQRYFHVCFVSGMRLRTAVIGAIYRKALVISSAARRSSTVGEIVNLMSVDAQRFMDLVTYINMIWSAPLQVVLALYFLWENLGPSVLAGVAVMILMVPINAVIAMKTKTYQVAQMKNKDSRIKLMNEMLNGIKVLKLYAWEMAFKEKVSQIRENELKVLKKAAYLGAVSTFTWVCAPFLVALSTFSVYVLIDDQNVLDAEKAFVSLALFNILRFPLNMLPMVISSMVQASVSLKRLRVFLSHEELQEDSVERPAAGGSPYSISIEDGVFSWSRSESPTLKRLNVRIPEGSLVAVVGHVGSGKSSLLSALLGEMDKMEGSVSVKGSVAYVPQQAWILNATLKNNIVFGQKRKEAWYHRVVEACALHQDLEILPAGDETEIGEKGVNLSGGQKQRVSLARAVYCDRSVYLLDDPLSAVDAHVGKHIFDHVIGPQGLLKDKTRILVTHGLSYLPQAHLVLVMVDGEITEVGSYQQLKEKEGAFAEFLRMY 866

HSP 2 Score: 586.26 bits (1510), Expect = 0.000e+0
Identity = 299/581 (51.46%), Postives = 416/581 (71.60%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            A  G VK SVF SY+++   L S   +  +  +   S+ AN +LS WT+    NGTQ   ++   LG+YG+LG  Q + +   + +++ G  LAS+ LH  +L ++LR+P SFF+ TP G ++NR  K++DT+D  IP  +++++ +   V+GS  +I +++P   L +  L  +Y+  QRFY+ +SRQLKR++S+ RSPIY+HF E+++G S IRA+   + FI + D   D NQ A+YP IV+ RWL   LE +GN ++  + + AV+ R ++  G  GLSISYALQ+T  L ++VRM+SD+E++ VAVER+KEY++ E EA W  E      DWP  G +   N+ +RYR  LDL +RN+N+ +  GEK+GIVGRTGAGKSSL L LFR+IEPAEG I ID  DI KLGLH+LRS+ITIIPQDP+LFSGT+RMNLDPF+ +SD ++W  LE S+LKSF++   + L +  SEGGENLS+GQ+QL+CLARALL+K+KVLVLDEATAA+D+ETDDLIQ++IR QF+ CTVLTIAHRLNTIMDY RV+VL++G++ E DSP NL+A +K  F+ MA D+GL
Sbjct:  932 ALTGRVKLSVFFSYLKAIGVLLSIISLLFFLSHNLLSLFANYWLSLWTDDPVVNGTQ--PNRLMRLGVYGALGVSQGVAVCGYSLSVSIGGILASRFLHQSMLFDVLRSPMSFFERTPSGNLVNRFAKEMDTIDSVIPMILKMFMGSLFNVVGSCIIILVATPMVALIIPFLGVLYFFVQRFYVASSRQLKRLESVSRSPIYTHFSETLLGTSVIRAFGEQERFIHESDQRVDHNQKAYYPGIVANRWLAVRLEFVGNCIVSFAALFAVLARESLSPGIMGLSISYALQLTASLTWLVRMSSDVETNIVAVERVKEYSDTEKEAEWRHEPPTVPPDWPTEGCIRITNFGLRYRSDLDLAIRNINVDISGGEKVGIVGRTGAGKSSLTLGLFRIIEPAEGNIFIDGVDIAKLGLHELRSRITIIPQDPVLFSGTLRMNLDPFDSYSDEDIWKALEFSHLKSFVSGLPDKLGHECSEGGENLSLGQRQLLCLARALLRKTKVLVLDEATAAIDMETDDLIQTTIRSQFEGCTVLTIAHRLNTIMDYTRVLVLDKGQMAEFDSPSNLIA-QKGAFYRMAKDSGL 1509

HSP 3 Score: 78.5666 bits (192), Expect = 5.988e-14
Identity = 70/280 (25.00%), Postives = 124/280 (44.29%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVE--FVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            LN +  + S +   +V+++R++ +   E     ++E   A    P S  +E    ++S    P     L+ LN+ +  G  + +VG  G+GKSSL  AL   ++  EG++              ++  +  +PQ   + + T++ N+    +  +     V+E   L   +     G +  + E G NLS GQKQ V LARA+     V +LD+  +AVD      I   +   +   K  T + + H L+ +     V+V+  G + E+ S Q L   E
Sbjct:  595 LNMLPMVISSMVQASVSLKRLRVFLSHEELQEDSVERPAAGGS-PYSISIEDGVFSWSRSESP----TLKRLNVRIPEGSLVAVVGHVGSGKSSLLSALLGEMDKMEGSV-------------SVKGSVAYVPQQAWILNATLKNNIVFGQKRKEAWYHRVVEACALHQDLEILPAGDETEIGEKGVNLSGGQKQRVSLARAVYCDRSVYLLDDPLSAVDAHVGKHIFDHVIGPQGLLKDKTRILVTHGLSYLPQAHLVLVMVDGEITEVGSYQQLKEKE 856

HSP 4 Score: 55.8398 bits (133), Expect = 4.545e-7
Identity = 58/241 (24.07%), Postives = 100/241 (41.49%), Query Frame = 2 
Query: 2024 PPD---EKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            PPD   E  ++I +    +       + NIN+++  G  V +VG  G+GK+SL   L   +    G +               R  I  IPQ     + +L+ N+       +    + +E   L   +  LP     E  E G NLS GQ+Q + LARA+ +   V +LD+  +A+D      I   +          T + + H L  +    ++ V+  G ++E  + + L+   G+F
Sbjct: 1263 PPDWPTEGCIRITNFGLRYRSDLDLAIRNINVDISGGEKVGIVGRTGAGKSSLTLGLFRIIEPAEGNIFIDGVDIAKLGLHELRSRITIIPQDPVLFSGTLRMNLDPFDSYSDEDIWKALEFSHLKSFVSGLPDKLGHECSEGGENLSLGQRQLLCLARALLRKTKVLVLDEATAAIDMETDDLIQTTI---RSQFEGCTVLTIAHRLNTIMDYTRVLVLDKGQMAEFDSPSNLIAQKGAF 1500
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Medaka
Match: abcc1 (multidrug resistance-associated protein 1 [Source:NCBI gene;Acc:101173789])

HSP 1 Score: 756.518 bits (1952), Expect = 0.000e+0
Identity = 406/910 (44.62%), Postives = 579/910 (63.63%), Query Frame = 2 
Query:   26 MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRG-----KFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLL-ASITVIYSRYRRLKFHDR----DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKP--VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            MG   F   CS  S++   W     WNT +PD+T CFQ T+L W+P L+LW+    Y+  + +       NRG       N  K+ +   +     L+   +  E   +        + P L  ++ +L   L +    KG+ SSG++  +WLL LL AS+T    R + L+  D+      +R  T    + L+ ++ +L+C +D                     PL S    D        PCPE   SFLS++TF W++G+++ GY++PL  KDL++L   D    +V  +  +W  E  +VK+T      E++  ++    P    +E   ++  +       +K + PS L AL  T    ++++ ++K+  D+L F  P+IL L I F+++P+   W G+  A  LF+ + ++S+I Q+Y+H C+V+GMR RTAVIG IYRKAL +SS +R+ +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +V+A+YFLW+ LGPSVLAGVA+MI ++PIN +I  K K  Q  QMK KD+RIKLMNE+L+GIK+LKLYAWE +F++ +  IR +E ++L+ A YL AVS  TW CAPFLVAL TF+ + L    +VL A KAFVSL+LFNIL FP++MLP VI   +QA VSLKR+  FL  +EL  ++VE       P  + I DG FSW ++E+P L  +N+ +PEGSLVAVVG VGSGK+SL+SAL+GE+ K+ G V  +GS+ Y+PQQAW  NA+L++NI+F +      Y+RV+EACAL +DL++LPAGD+TEIGEKG+NLSGGQKQR+SLARAVY D SVYLLDDPLSAVD+HVGKHIFD VIGP GLL  KTRILVTHGL+YLP+   + VM DG ++E G++ +L +  G+FAEF+R Y
Sbjct:    1 MGLDRF---CSPNSSE-PFWDWNRSWNTSNPDLTPCFQSTVLVWVPCLYLWLCAPFYLMYMRS------HNRGYICMSHLNKAKTAVGFLLWIICWLDVFYSFWERSHSRNVAAVHLVSPTLLGLTMLLATLLVQYERMKGVQSSGIMLIFWLLALLCASVTF---RSKILQAQDQPEAVSGWRYTTFYVYYALLLLALVLSCLSD-------------------QMPLFSQAVKDPN------PCPEPGASFLSRITFWWISGMMLSGYKRPLEEKDLWSLNPEDRSHCVVPQLLRRWTAECHKVKRT------EEKMLYSPKQPPHGENKEVRAVEESEILIVKSPKKSREPSLLWALCLTFAPHFLVSCLYKLIQDILMFVGPEILRLLILFVNDPDAPSWQGYFYAALLFVCTCVQSLILQRYFHVCFVSGMRLRTAVIGAIYRKALVISSAARRSSTVGEIVNLMSVDAQRFMDLVTYINMIWSAPLQVVLALYFLWENLGPSVLAGVAVMILMVPINAVIAMKTKTYQVAQMKNKDSRIKLMNEMLNGIKVLKLYAWEMAFKEKVSQIRENELKVLKKAAYLGAVSTFTWVCAPFLVALSTFSVYVLIDDQNVLDAEKAFVSLALFNILRFPLNMLPMVISSMVQASVSLKRLRVFLSHEELQEDSVERPAAGGSPYSISIEDGVFSWSRSESPTLKRLNVRIPEGSLVAVVGHVGSGKSSLLSALLGEMDKMEGSVSVKGSVAYVPQQAWILNATLKNNIVFGQKRKEAWYHRVVEACALHQDLEILPAGDETEIGEKGVNLSGGQKQRVSLARAVYCDRSVYLLDDPLSAVDAHVGKHIFDHVIGPQGLLKDKTRILVTHGLSYLPQAHLVLVMVDGEITEVGSYQQLKEKEGAFAEFLRMY 866

HSP 2 Score: 551.592 bits (1420), Expect = 6.450e-169
Identity = 281/546 (51.47%), Postives = 389/546 (71.25%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDR 4639
            A  G VK SVF SY+++   L S   +  +  +   S+ AN +LS WT+    NGTQ   ++   LG+YG+LG  Q + +   + +++ G  LAS+ LH  +L ++LR+P SFF+ TP G ++NR  K++DT+D  IP  +++++ +   V+GS  +I +++P   L +  L  +Y+  QRFY+ +SRQLKR++S+ RSPIY+HF E+++G S IRA+   + FI + D   D NQ A+YP IV+ RWL   LE +GN ++  + + AV+ R ++  G  GLSISYALQ+T  L ++VRM+SD+E++ VAVER+KEY++ E EA W  E      DWP  G +   N+ +RYR  LDL +RN+N+ +  GEK+GIVGRTGAGKSSL L LFR+IEPAEG I ID  DI KLGLH+LRS+ITIIPQDP+LFSGT+RMNLDPF+ +SD ++W  LE S+LKSF++   + L +  SEGGENLS+GQ+QL+CLARALL+K+KVLVLDEATAA+D+ETDDLIQ++IR QF+ CTVLTIAHRLNTIMDY R
Sbjct:  932 ALTGRVKLSVFFSYLKAIGVLLSIISLLFFLSHNLLSLFANYWLSLWTDDPVVNGTQ--PNRLMRLGVYGALGVSQGVAVCGYSLSVSIGGILASRFLHQSMLFDVLRSPMSFFERTPSGNLVNRFAKEMDTIDSVIPMILKMFMGSLFNVVGSCIIILVATPMVALIIPFLGVLYFFVQRFYVASSRQLKRLESVSRSPIYTHFSETLLGTSVIRAFGEQERFIHESDQRVDHNQKAYYPGIVANRWLAVRLEFVGNCIVSFAALFAVLARESLSPGIMGLSISYALQLTASLTWLVRMSSDVETNIVAVERVKEYSDTEKEAEWRHEPPTVPPDWPTEGCIRITNFGLRYRSDLDLAIRNINVDISGGEKVGIVGRTGAGKSSLTLGLFRIIEPAEGNIFIDGVDIAKLGLHELRSRITIIPQDPVLFSGTLRMNLDPFDSYSDEDIWKALEFSHLKSFVSGLPDKLGHECSEGGENLSLGQRQLLCLARALLRKTKVLVLDEATAAIDMETDDLIQTTIRSQFEGCTVLTIAHRLNTIMDYTR 1475

HSP 3 Score: 78.5666 bits (192), Expect = 5.150e-14
Identity = 70/280 (25.00%), Postives = 124/280 (44.29%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVE--FVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            LN +  + S +   +V+++R++ +   E     ++E   A    P S  +E    ++S    P     L+ LN+ +  G  + +VG  G+GKSSL  AL   ++  EG++              ++  +  +PQ   + + T++ N+    +  +     V+E   L   +     G +  + E G NLS GQKQ V LARA+     V +LD+  +AVD      I   +   +   K  T + + H L+ +     V+V+  G + E+ S Q L   E
Sbjct:  595 LNMLPMVISSMVQASVSLKRLRVFLSHEELQEDSVERPAAGGS-PYSISIEDGVFSWSRSESP----TLKRLNVRIPEGSLVAVVGHVGSGKSSLLSALLGEMDKMEGSV-------------SVKGSVAYVPQQAWILNATLKNNIVFGQKRKEAWYHRVVEACALHQDLEILPAGDETEIGEKGVNLSGGQKQRVSLARAVYCDRSVYLLDDPLSAVDAHVGKHIFDHVIGPQGLLKDKTRILVTHGLSYLPQAHLVLVMVDGEITEVGSYQQLKEKE 856
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Medaka
Match: abcc3 (ATP binding cassette subfamily C member 3 [Source:NCBI gene;Acc:101175305])

HSP 1 Score: 756.133 bits (1951), Expect = 0.000e+0
Identity = 397/884 (44.91%), Postives = 556/884 (62.90%), Query Frame = 2 
Query:  101 WNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLL-------NFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDR--DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVK-QTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVE-VSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            ++T  PD+ +CFQ ++L  +P ++LW+   +Y+        F  +   +  I  S L  F   F LL       +   +  E      PPP  ++ P++   + +L   L +     G+ SSGVLF +W L +L +I    S+  +        D  R  T    F LV    IL CF                   +E  PL S   D  T P    PCPE    FLS +TF W T L +KGY+ PL  KDL++L++ D+ +T+V  +  +W +E  + + Q     + +      S    L  +E E       +   + ++ +K PSFLRA+    G  +++   +K+  D++TF  PQ+L L I+F    +  +W G+ LA  +F  + ++++I  +++  C+VTGM  RTA+IG IYRKAL +++ +++ +TVGEIVNLMSVD+Q+  D+ +FL++LW+AP+ I++A+YFLW+ LGPSVLAGVA+M+ LIP+N  I  K +  Q +QM+ KD R+KLMNEIL+GIK+LKLYAWE SF+Q + +IR  E  +LR   YL A+S + W  APFLVAL +F  F     ++VL A +AFVSLSLFNIL FP++MLP VI    QA VSLKRI  FL  DELD ++V+  + P +  V +V+GTF+W K + PVL ++++ VP GSL+AVVG VG GK+SLISAL+GE+ K+ G V  +GS+ Y+PQQAW +NA+L+DNILF       KY  V++ACALT+DL+VLP GDQTEIGEKGINLSGGQ+QR+SLARA+Y D  VYLLDDPLSAVD+HV KHIFD++IGP GLL  KTRILVTHG+++LP+VD I V+  G VSE G+  ELLK NG+FAEF+R Y
Sbjct:   18 FHTDQPDLPVCFQLSVLACLPCIYLWVVSPVYL--------FYLKRNNRGYIMVSILNRFKTVFGLLLWIVCWTDLFYSFHEMQQGQTPPPIFFITPLVLGTTMLLATVLIQYERLHGVQSSGVLFIFWFLSVLCAIVPFRSKILKASGESEVPDKLRFTTFYVYFSLVVCELILCCF-------------------NERPPLFS---DTVTDPN---PCPETTAGFLSSMTFWWFTSLALKGYKMPLEAKDLWSLKKRDSSETMVPRLLAEWRKEEAKARSQQNLSGQAQYAKLPPSKANHLSGDEAEDNGPKEGDVLLSNQKAQKQPSFLRAILKAFGPYFLIGSAYKLLQDVITFINPQLLSLLISFTKQEDVPLWWGYTLAFLMFFTAFLQTLILHRHFQYCFVTGMNVRTALIGAIYRKALVITNAAKRSSTVGEIVNLMSVDAQRFMDLTAFLNMLWSAPLQIMLALYFLWENLGPSVLAGVAVMVMLIPLNAFIAMKTRAYQVEQMQHKDARLKLMNEILNGIKVLKLYAWEESFKQKVLDIRQKELNVLRKTAYLGALSTMAWTSAPFLVALTSFAVFVSVDENNVLDAKRAFVSLSLFNILRFPLNMLPQVISSIAQASVSLKRIQNFLSHDELDPDSVDRKNTPGDFSVTVVNGTFTWAKEDPPVLHSVSVMVPRGSLLAVVGPVGCGKSSLISALLGEMEKLEGEVSIQGSVAYVPQQAWIQNATLRDNILFGNAYNEQKYCSVLDACALTQDLEVLPGGDQTEIGEKGINLSGGQRQRVSLARALYSDADVYLLDDPLSAVDAHVAKHIFDRLIGPDGLLKEKTRILVTHGISFLPQVDNIMVLGAGRVSEMGSHQELLKQNGAFAEFLRNY 868

HSP 2 Score: 627.861 bits (1618), Expect = 0.000e+0
Identity = 305/581 (52.50%), Postives = 418/581 (71.94%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            AE G VK  V+L Y+++   L S  ++  Y      ++G+N++LS WT   + N TQ  ++    + +Y +LG  Q + ++I ++ LA G   A++ LH  LL N L  P SFFDTTP+GRI+NR  KD+  +D ++P+T+ ++L T    + ++ VI  S+PYF L +  L  +Y   QRFY+ +SRQLKR++S+ RSPIYSHF E++ G+S IRAY   D F+   D   DENQ ++YP IVS RWL   +E IGN ++L + + AV+ + T+  G  GLS+SYALQ+T  LN+MVRMTSDLE++ VAVER+KEY+E + EAPW +E+ +   +WP  G+VEF  YSVRYR GLDLVL+N+ + V  GEK+GIVGRTGAGKSS+ L LFRL+E A G I ID   I ++GLHDLRS++TIIPQ+P+LFSGT+RMNLDPF+++SD ++W  LE S+L  F+      LQ   +EGGENLSVGQ+QLVCLARALL+K+++L+LDEATAA+DLETDDLIQS+IR QF+  TV TIAHRLNTIMDY RV+VL++G++ E D+P NL++ ++ IF+ MA DAGL
Sbjct:  964 AETGRVKTKVYLEYVKAVGVLLSVLILLLYGCQSAAAIGSNIWLSQWTNDAAGNHTQ--ENVQMRVSVYAALGIAQGILVMISSYTLAMGNISAARRLHANLLTNKLHTPQSFFDTTPIGRIINRFSKDVYVIDEALPSTVLMFLGTFCASLSTMIVIVCSTPYFALIIPVLALIYVFVQRFYVASSRQLKRLESVSRSPIYSHFSETVTGSSVIRAYGRLDAFVLMSDAKVDENQRSYYPGIVSNRWLGVRIEFIGNCIVLFAALFAVIWKETLNPGLVGLSVSYALQVTMSLNWMVRMTSDLENNIVAVERVKEYSETKPEAPWEVEDKKPPPEWPTDGKVEFHGYSVRYRDGLDLVLKNITLDVKGGEKIGIVGRTGAGKSSMTLCLFRLLEAAAGEITIDGVKIAEIGLHDLRSRLTIIPQEPVLFSGTLRMNLDPFDKYSDEDVWKALEHSHLHGFVRNQPAQLQMECAEGGENLSVGQRQLVCLARALLRKTRILILDEATAAIDLETDDLIQSTIRTQFENSTVFTIAHRLNTIMDYTRVLVLDKGKIAEFDTPTNLIS-KRGIFYGMAKDAGL 1541

HSP 3 Score: 100.138 bits (248), Expect = 1.488e-20
Identity = 105/411 (25.55%), Postives = 184/411 (44.77%), Query Frame = 2 
Query: 3497 LLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKC-DIMTDE----NQMAWYPNIVSYRWLQF-YLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLET-----DDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLL 4696
            ++ L+PL A   M  R   Y   Q++  D+  +        E + G   ++ Y   + F +K  DI   E     + A+   + +  W    +L  + +  + +S    V   + + +  A +S+S    +   LN + ++ S +   +V+++RI+ +   +   P +++      D+     V  VN +  +      VL +++++V  G  L +VG  G GKSSL  AL   +E  EG + I             +  +  +PQ   + + T+R N+   N +++ +  SVL+   L   +     G Q  + E G NLS GQ+Q V LARAL   + V +LD+  +AVD        D LI        K+ T + + H ++ +   D +MVL  GRV E+ S Q LL
Sbjct:  475 MVMLIPLNAFIAMKTR--AYQVEQMQHKDARLK-----LMNEILNGIKVLKLYAWEESFKQKVLDIRQKELNVLRKTAYLGALSTMAWTSAPFLVALTSFAVFVS----VDENNVLDAKRAFVSLSLFNILRFPLNMLPQVISSIAQASVSLKRIQNFLSHDELDPDSVDRKNTPGDF----SVTVVNGTFTWAKEDPPVLHSVSVMVPRGSLLAVVGPVGCGKSSLISALLGEMEKLEGEVSI-------------QGSVAYVPQQAWIQNATLRDNILFGNAYNEQKYCSVLDACALTQDLEVLPGGDQTEIGEKGINLSGGQRQRVSLARALYSDADVYLLDDPLSAVDAHVAKHIFDRLIGPD--GLLKEKTRILVTHGISFLPQVDNIMVLGAGRVSEMGSHQELL 855

HSP 4 Score: 72.4034 bits (176), Expect = 4.491e-12
Identity = 55/216 (25.46%), Postives = 94/216 (43.52%), Query Frame = 2 
Query: 2090 VLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            VL NI ++V  G  + +VG  G+GK+S+   L   L   +G +               R  +  IPQ+    + +L+ N+       +    + +E   L   ++  PA  Q E  E G NLS GQ+Q + LARA+ +   + +LD+  +A+D      I   +        + T   + H L  +    ++ V+  G ++E  T T L+   G F
Sbjct: 1320 VLKNITLDVKGGEKIGIVGRTGAGKSSMTLCLFRLLEAAAGEITIDGVKIAEIGLHDLRSRLTIIPQEPVLFSGTLRMNLDPFDKYSDEDVWKALEHSHLHGFVRNQPAQLQMECAEGGENLSVGQRQLVCLARALLRKTRILILDEATAAIDLETDDLIQSTI---RTQFENSTVFTIAHRLNTIMDYTRVLVLDKGKIAEFDTPTNLISKRGIF 1532
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Medaka
Match: abcc1 (multidrug resistance-associated protein 1 [Source:NCBI gene;Acc:101173789])

HSP 1 Score: 756.133 bits (1951), Expect = 0.000e+0
Identity = 402/892 (45.07%), Postives = 575/892 (64.46%), Query Frame = 2 
Query:  101 WNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFK----STLIAFIL--------FFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLL-ASITVIYSRYRRLKFHDR----DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKP--VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            WNT +PD+T CFQ T+L W+P L+LW+    Y+  + +       NRG   +       T + F+L        F+       + + +  +L  P  L L    + + + LL+   R+   KG+ SSG++  +WLL LL AS+T    R + L+  D+      +R  T    + L+ ++ +L+C +D                     PL S    D        PCPE   SFLS++TF W++G+++ GY++PL  KDL++L   D    +V  +  +W  E  +VK+T      E++  ++    P    +E   ++  +       +K + PS L AL  T    ++++ ++K+  D+L F  P+IL L I F+++P+   W G+  A  LF+ + ++S+I Q+Y+H C+V+GMR RTAVIG IYRKAL +SS +R+ +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +V+A+YFLW+ LGPSVLAGVA+MI ++PIN +I  K K  Q  QMK KD+RIKLMNE+L+GIK+LKLYAWE +F++ +  IR +E ++L+ A YL AVS  TW CAPFLVAL TF+ + L    +VL A KAFVSL+LFNIL FP++MLP VI   +QA VSLKR+  FL  +EL  ++VE       P  + I DG FSW ++E+P L  +N+ +PEGSLVAVVG VGSGK+SL+SAL+GE+ K+ G V  +GS+ Y+PQQAW  NA+L++NI+F +      Y+RV+EACAL +DL++LPAGD+TEIGEKG+NLSGGQKQR+SLARAVY D SVYLLDDPLSAVD+HVGKHIFD VIGP GLL  KTRILVTHGL+YLP+   + VM DG ++E G++ +L +  G+FAEF+R Y
Sbjct:   60 WNTSNPDLTPCFQSTVLVWVPCLYLWLCAPFYLMYMRS------HNRGYICMSHLNKAKTAVGFLLWIICWLDVFYSFWERSHSRNVAAVHLVSPTLLGL----TMLLATLLVQYERM---KGVQSSGIMLIFWLLALLCASVTF---RSKILQAQDQPEAVSGWRYTTFYVYYALLLLALVLSCLSD-------------------QMPLFSQAVKDPN------PCPEPGASFLSRITFWWISGMMLSGYKRPLEEKDLWSLNPEDRSHCVVPQLLRRWTAECHKVKRT------EEKMLYSPKQPPHGENKEVRAVEESEILIVKSPKKSREPSLLWALCLTFAPHFLVSCLYKLIQDILMFVGPEILRLLILFVNDPDAPSWQGYFYAALLFVCTCVQSLILQRYFHVCFVSGMRLRTAVIGAIYRKALVISSAARRSSTVGEIVNLMSVDAQRFMDLVTYINMIWSAPLQVVLALYFLWENLGPSVLAGVAVMILMVPINAVIAMKTKTYQVAQMKNKDSRIKLMNEMLNGIKVLKLYAWEMAFKEKVSQIRENELKVLKKAAYLGAVSTFTWVCAPFLVALSTFSVYVLIDDQNVLDAEKAFVSLALFNILRFPLNMLPMVISSMVQASVSLKRLRVFLSHEELQEDSVERPAAGGSPYSISIEDGVFSWSRSESPTLKRLNVRIPEGSLVAVVGHVGSGKSSLLSALLGEMDKMEGSVSVKGSVAYVPQQAWILNATLKNNIVFGQKRKEAWYHRVVEACALHQDLEILPAGDETEIGEKGVNLSGGQKQRVSLARAVYCDRSVYLLDDPLSAVDAHVGKHIFDHVIGPQGLLKDKTRILVTHGLSYLPQAHLVLVMVDGEITEVGSYQQLKEKEGAFAEFLRMY 904

HSP 2 Score: 551.592 bits (1420), Expect = 1.382e-168
Identity = 281/546 (51.47%), Postives = 389/546 (71.25%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDR 4639
            A  G VK SVF SY+++   L S   +  +  +   S+ AN +LS WT+    NGTQ   ++   LG+YG+LG  Q + +   + +++ G  LAS+ LH  +L ++LR+P SFF+ TP G ++NR  K++DT+D  IP  +++++ +   V+GS  +I +++P   L +  L  +Y+  QRFY+ +SRQLKR++S+ RSPIY+HF E+++G S IRA+   + FI + D   D NQ A+YP IV+ RWL   LE +GN ++  + + AV+ R ++  G  GLSISYALQ+T  L ++VRM+SD+E++ VAVER+KEY++ E EA W  E      DWP  G +   N+ +RYR  LDL +RN+N+ +  GEK+GIVGRTGAGKSSL L LFR+IEPAEG I ID  DI KLGLH+LRS+ITIIPQDP+LFSGT+RMNLDPF+ +SD ++W  LE S+LKSF++   + L +  SEGGENLS+GQ+QL+CLARALL+K+KVLVLDEATAA+D+ETDDLIQ++IR QF+ CTVLTIAHRLNTIMDY R
Sbjct:  970 ALTGRVKLSVFFSYLKAIGVLLSIISLLFFLSHNLLSLFANYWLSLWTDDPVVNGTQ--PNRLMRLGVYGALGVSQGVAVCGYSLSVSIGGILASRFLHQSMLFDVLRSPMSFFERTPSGNLVNRFAKEMDTIDSVIPMILKMFMGSLFNVVGSCIIILVATPMVALIIPFLGVLYFFVQRFYVASSRQLKRLESVSRSPIYTHFSETLLGTSVIRAFGEQERFIHESDQRVDHNQKAYYPGIVANRWLAVRLEFVGNCIVSFAALFAVLARESLSPGIMGLSISYALQLTASLTWLVRMSSDVETNIVAVERVKEYSDTEKEAEWRHEPPTVPPDWPTEGCIRITNFGLRYRSDLDLAIRNINVDISGGEKVGIVGRTGAGKSSLTLGLFRIIEPAEGNIFIDGVDIAKLGLHELRSRITIIPQDPVLFSGTLRMNLDPFDSYSDEDIWKALEFSHLKSFVSGLPDKLGHECSEGGENLSLGQRQLLCLARALLRKTKVLVLDEATAAIDMETDDLIQTTIRSQFEGCTVLTIAHRLNTIMDYTR 1513

HSP 3 Score: 78.5666 bits (192), Expect = 5.835e-14
Identity = 70/280 (25.00%), Postives = 124/280 (44.29%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVE--FVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            LN +  + S +   +V+++R++ +   E     ++E   A    P S  +E    ++S    P     L+ LN+ +  G  + +VG  G+GKSSL  AL   ++  EG++              ++  +  +PQ   + + T++ N+    +  +     V+E   L   +     G +  + E G NLS GQKQ V LARA+     V +LD+  +AVD      I   +   +   K  T + + H L+ +     V+V+  G + E+ S Q L   E
Sbjct:  633 LNMLPMVISSMVQASVSLKRLRVFLSHEELQEDSVERPAAGGS-PYSISIEDGVFSWSRSESP----TLKRLNVRIPEGSLVAVVGHVGSGKSSLLSALLGEMDKMEGSV-------------SVKGSVAYVPQQAWILNATLKNNIVFGQKRKEAWYHRVVEACALHQDLEILPAGDETEIGEKGVNLSGGQKQRVSLARAVYCDRSVYLLDDPLSAVDAHVGKHIFDHVIGPQGLLKDKTRILVTHGLSYLPQAHLVLVMVDGEITEVGSYQQLKEKE 894
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Medaka
Match: abcc1 (multidrug resistance-associated protein 1 [Source:NCBI gene;Acc:101173789])

HSP 1 Score: 755.747 bits (1950), Expect = 0.000e+0
Identity = 402/892 (45.07%), Postives = 575/892 (64.46%), Query Frame = 2 
Query:  101 WNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFK----STLIAFIL--------FFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLL-ASITVIYSRYRRLKFHDR----DLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKP--VKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTY 2719
            WNT +PD+T CFQ T+L W+P L+LW+    Y+  + +       NRG   +       T + F+L        F+       + + +  +L  P  L L    + + + LL+   R+   KG+ SSG++  +WLL LL AS+T    R + L+  D+      +R  T    + L+ ++ +L+C +D                     PL S    D        PCPE   SFLS++TF W++G+++ GY++PL  KDL++L   D    +V  +  +W  E  +VK+T      E++  ++    P    +E   ++  +       +K + PS L AL  T    ++++ ++K+  D+L F  P+IL L I F+++P+   W G+  A  LF+ + ++S+I Q+Y+H C+V+GMR RTAVIG IYRKAL +SS +R+ +TVGEIVNLMSVD+Q+  D+ ++++++W+AP+ +V+A+YFLW+ LGPSVLAGVA+MI ++PIN +I  K K  Q  QMK KD+RIKLMNE+L+GIK+LKLYAWE +F++ +  IR +E ++L+ A YL AVS  TW CAPFLVAL TF+ + L    +VL A KAFVSL+LFNIL FP++MLP VI   +QA VSLKR+  FL  +EL  ++VE       P  + I DG FSW ++E+P L  +N+ +PEGSLVAVVG VGSGK+SL+SAL+GE+ K+ G V  +GS+ Y+PQQAW  NA+L++NI+F +      Y+RV+EACAL +DL++LPAGD+TEIGEKG+NLSGGQKQR+SLARAVY D SVYLLDDPLSAVD+HVGKHIFD VIGP GLL  KTRILVTHGL+YLP+   + VM DG ++E G++ +L +  G+FAEF+R Y
Sbjct:   22 WNTSNPDLTPCFQSTVLVWVPCLYLWLCAPFYLMYMRS------HNRGYICMSHLNKAKTAVGFLLWIICWLDVFYSFWERSHSRNVAAVHLVSPTLLGL----TMLLATLLVQYERM---KGVQSSGIMLIFWLLALLCASVTF---RSKILQAQDQPEAVSGWRYTTFYVYYALLLLALVLSCLSD-------------------QMPLFSQAVKDPN------PCPEPGASFLSRITFWWISGMMLSGYKRPLEEKDLWSLNPEDRSHCVVPQLLRRWTAECHKVKRT------EEKMLYSPKQPPHGENKEVRAVEESEILIVKSPKKSREPSLLWALCLTFAPHFLVSCLYKLIQDILMFVGPEILRLLILFVNDPDAPSWQGYFYAALLFVCTCVQSLILQRYFHVCFVSGMRLRTAVIGAIYRKALVISSAARRSSTVGEIVNLMSVDAQRFMDLVTYINMIWSAPLQVVLALYFLWENLGPSVLAGVAVMILMVPINAVIAMKTKTYQVAQMKNKDSRIKLMNEMLNGIKVLKLYAWEMAFKEKVSQIRENELKVLKKAAYLGAVSTFTWVCAPFLVALSTFSVYVLIDDQNVLDAEKAFVSLALFNILRFPLNMLPMVISSMVQASVSLKRLRVFLSHEELQEDSVERPAAGGSPYSISIEDGVFSWSRSESPTLKRLNVRIPEGSLVAVVGHVGSGKSSLLSALLGEMDKMEGSVSVKGSVAYVPQQAWILNATLKNNIVFGQKRKEAWYHRVVEACALHQDLEILPAGDETEIGEKGVNLSGGQKQRVSLARAVYCDRSVYLLDDPLSAVDAHVGKHIFDHVIGPQGLLKDKTRILVTHGLSYLPQAHLVLVMVDGEITEVGSYQQLKEKEGAFAEFLRMY 866

HSP 2 Score: 551.592 bits (1420), Expect = 6.320e-169
Identity = 281/546 (51.47%), Postives = 389/546 (71.25%), Query Frame = 2 
Query: 3002 AEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDR 4639
            A  G VK SVF SY+++   L S   +  +  +   S+ AN +LS WT+    NGTQ   ++   LG+YG+LG  Q + +   + +++ G  LAS+ LH  +L ++LR+P SFF+ TP G ++NR  K++DT+D  IP  +++++ +   V+GS  +I +++P   L +  L  +Y+  QRFY+ +SRQLKR++S+ RSPIY+HF E+++G S IRA+   + FI + D   D NQ A+YP IV+ RWL   LE +GN ++  + + AV+ R ++  G  GLSISYALQ+T  L ++VRM+SD+E++ VAVER+KEY++ E EA W  E      DWP  G +   N+ +RYR  LDL +RN+N+ +  GEK+GIVGRTGAGKSSL L LFR+IEPAEG I ID  DI KLGLH+LRS+ITIIPQDP+LFSGT+RMNLDPF+ +SD ++W  LE S+LKSF++   + L +  SEGGENLS+GQ+QL+CLARALL+K+KVLVLDEATAA+D+ETDDLIQ++IR QF+ CTVLTIAHRLNTIMDY R
Sbjct:  932 ALTGRVKLSVFFSYLKAIGVLLSIISLLFFLSHNLLSLFANYWLSLWTDDPVVNGTQ--PNRLMRLGVYGALGVSQGVAVCGYSLSVSIGGILASRFLHQSMLFDVLRSPMSFFERTPSGNLVNRFAKEMDTIDSVIPMILKMFMGSLFNVVGSCIIILVATPMVALIIPFLGVLYFFVQRFYVASSRQLKRLESVSRSPIYTHFSETLLGTSVIRAFGEQERFIHESDQRVDHNQKAYYPGIVANRWLAVRLEFVGNCIVSFAALFAVLARESLSPGIMGLSISYALQLTASLTWLVRMSSDVETNIVAVERVKEYSDTEKEAEWRHEPPTVPPDWPTEGCIRITNFGLRYRSDLDLAIRNINVDISGGEKVGIVGRTGAGKSSLTLGLFRIIEPAEGNIFIDGVDIAKLGLHELRSRITIIPQDPVLFSGTLRMNLDPFDSYSDEDIWKALEFSHLKSFVSGLPDKLGHECSEGGENLSLGQRQLLCLARALLRKTKVLVLDEATAAIDMETDDLIQTTIRSQFEGCTVLTIAHRLNTIMDYTR 1475

HSP 3 Score: 78.5666 bits (192), Expect = 6.097e-14
Identity = 70/280 (25.00%), Postives = 124/280 (44.29%), Query Frame = 2 
Query: 3881 LNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVE--FVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSI---RRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            LN +  + S +   +V+++R++ +   E     ++E   A    P S  +E    ++S    P     L+ LN+ +  G  + +VG  G+GKSSL  AL   ++  EG++              ++  +  +PQ   + + T++ N+    +  +     V+E   L   +     G +  + E G NLS GQKQ V LARA+     V +LD+  +AVD      I   +   +   K  T + + H L+ +     V+V+  G + E+ S Q L   E
Sbjct:  595 LNMLPMVISSMVQASVSLKRLRVFLSHEELQEDSVERPAAGGS-PYSISIEDGVFSWSRSESP----TLKRLNVRIPEGSLVAVVGHVGSGKSSLLSALLGEMDKMEGSV-------------SVKGSVAYVPQQAWILNATLKNNIVFGQKRKEAWYHRVVEACALHQDLEILPAGDETEIGEKGVNLSGGQKQRVSLARAVYCDRSVYLLDDPLSAVDAHVGKHIFDHVIGPQGLLKDKTRILVTHGLSYLPQAHLVLVMVDGEITEVGSYQQLKEKE 856
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Planmine SMEST
Match: SMESG000057252.1 (SMESG000057252.1)

HSP 1 Score: 2976.42 bits (7715), Expect = 0.000e+0
Identity = 1572/1574 (99.87%), Postives = 1573/1574 (99.94%), Query Frame = 2 
Query:   26 MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSNYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYLXXXXXXXXXXXXXXXXXXXXXXXXHTISRLSSNIDXXXXXXXXXXXXNPLTDSRRSHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVAEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPILSAISSILLIYLNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKF KKLEKQNGFTSNYKPLKSEEEETEIDFVQNTNNNKEQKKKSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFE+NIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYLEQEEEENVEEDSEDESKELKKELKHTISRLSSNIDSESEYQKSSHSSNPLTDSRRSHKRQSSVRLSKSRSVLAEEAEAELKKAKKKRLIEEEVAEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTASGVIGSIFVISISSPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA
Sbjct:    1 MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPILSAISSILLIYLNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFHKKLEKQNGFTSNYKPLKSEEEETEIDFVQNTNNNKEQKKKSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEENIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYLEQEEEENVEEDSEDESKELKKELKHTISRLSSNIDSESEYQKSSHSSNPLTDSRRSHKRQSSVRLSKSRSVLAEEAEAELKKAKKKRLIEEEVAEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTASGVIGSIFVISISSPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 1574
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Planmine SMEST
Match: SMESG000039911.1 (SMESG000039911.1)

HSP 1 Score: 2217.19 bits (5744), Expect = 0.000e+0
Identity = 1146/1545 (74.17%), Postives = 1335/1545 (86.41%), Query Frame = 2 
Query:   26 MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLLSLIPDDKTIPINRI-PCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQ-TKFRKKLEKQNGFTSNYKPLKS-----EEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYLXXXXXXXXXXXXXXXXXXXXXXXXHTISRLSSNIDXXXXXXXXXXXXNPLTDSRRSHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVAEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDR 4639
            M K +FT LCS KS+DW LWYD IGW+T +PDITLCFQYTILNWIPL FLWIS MIYIPIL N+ S+ YR  GK NIFK+ LIA ++F H+LNF  T++ES+ N  PP  LYLQPILS +SSILLIYLNR+IYKKGIHSSGVLFFYWL+QL AS+ V+YSRY RL+  + D+F TVTAT EF+LV +SF  NCF+D AV ++ E +++ + D +E+QPLL+L   ++T+  ++I  CPE + SFLSKLTF W TG++IKGYR+PL F DLFAL   DTC  IV  ME +W+RE  R     + RKK +  + FT++Y+ L       ++E  E          K+   K+PSFLR+L +TIG PYMLAG+ K+AYDLLTF QP +LG FI+FI+N  DYVWHGF+ A CLF+I MIRSVI QQYYHGCYVTGMR+RTA+IGIIYRKALKLSSTSRK TTVGEIVNLMSVDSQKLQDVP +LH+LW++PI IVIA+Y LWQELG +VLAG+ALMICLIP+NGIIGS++KKLQ KQMKMKDNRIKLM+EILSGIKILKLYAWENSF +NI+ IRNDEC +LRSATYLNA SAV WFCAPFLVA+C+F AF LSS+ +VLT NKAFVSLSLFNIL+ PMSMLPG IV+GIQAYVSL R+NKFL+GDELD +NVE+SPP+E PVK++DGTFSWGK + P L  INM+V EGSLVAVVGTVGSGKTSLISALIGELY+V+GRV+CRGSI Y+PQQAWC+NASLQDNI+F KP++ HKYN VIEACALTEDLKVLP GDQTEIGEKG+NLSGGQKQRISLARAVYQD SVY+ DDPLSAVDSHVGKHIF++VIGP GLLS KTRILVTHGLT+LPKVD IFVMKDG +SE+GTF EL+KNNG FAEF+RTYLEQEEEE   EDSEDE+KELK ELK TIS+LSS +D+++E QKS+ S+  L +S++SH+RQSSVRLSKS+SVLAEEAE +++KAKK +LIE+EVAE GGVKFSVFLSY+RSSTYLFS   V SY LY+ CSVGAN+FLSYW+E+G+T+ +QN     FYLGIYG++GAGQ +FILIENFALAYGTF+ASKSLH LLLK+ILRAP+SFFDTTPLGRILNRIGKDIDTVDV+IPTTIR+WL TA+GV  S+ VISISSPYFL+AL+PL  MYYMAQRFYI TSRQLKRIDSIKRSPIYSHFQE+IVGA+SIRAYKV++DFI KCD M DENQMAWYPNI+SYRWLQ  LETIGN+VILL+G+L V+TR TIGSGYAGLS+SYALQITG LN+MVRMT DLES+TVAVERIKEYA+IESEAPW+ EE +  ++WP SG+VEF+NYSVRYRPGL+LVLRNLN+ V AGEKLGIVGRTGAGKSSLALALFRLIEPAEGTI IDN ++++LGLHDLRSKITIIPQDP+LFSGT+RMNLDPFNQ+SDGELWS LE SYLKSF++KT EGL ++VSE GEN+SVGQ+QLVCLARALLK++KVLVLDEATAA+DLETDDLIQ+SIR+QFK CTVLTIAHRLNTI+DYDR
Sbjct:    1 MSKIYFTGLCSSKSDDWTLWYDKIGWDTPNPDITLCFQYTILNWIPLSFLWISSMIYIPILLNRISYSYRTLGKLNIFKTILIALLIFIHILNFFRTVNESVKNRSPPSVLYLQPILSGLSSILLIYLNRIIYKKGIHSSGVLFFYWLIQLCASVIVVYSRYSRLQTSNPDIFSTVTATLEFILVLISFCANCFSDPAVLSNQEILDS-EDDIEESQPLLNL-SSNETVNRHKIKACPEKKASFLSKLTFIWFTGMIIKGYRRPLIFSDLFALLNEDTCRNIVPKMEKEWSRELDRTSALNRDRKKPQGHDNFTASYQRLSQYISNLQDESDE---------RKKHTIKTPSFLRSLVYTIGLPYMLAGIHKLAYDLLTFTQPLLLGFFISFIENKKDYVWHGFIYAACLFVIGMIRSVILQQYYHGCYVTGMRTRTAIIGIIYRKALKLSSTSRKNTTVGEIVNLMSVDSQKLQDVPVYLHLLWSSPIIIVIAMYLLWQELGAAVLAGIALMICLIPVNGIIGSRIKKLQNKQMKMKDNRIKLMSEILSGIKILKLYAWENSFCENIEKIRNDECVVLRSATYLNAFSAVIWFCAPFLVAVCSFAAFVLSSTENVLTPNKAFVSLSLFNILNVPMSMLPGTIVFGIQAYVSLVRVNKFLLGDELDQDNVEISPPNESPVKVIDGTFSWGKCDPPTLTEINMDVSEGSLVAVVGTVGSGKTSLISALIGELYRVAGRVLCRGSIAYVPQQAWCQNASLQDNIIFRKPMVRHKYNSVIEACALTEDLKVLPGGDQTEIGEKGVNLSGGQKQRISLARAVYQDASVYIFDDPLSAVDSHVGKHIFNKVIGPDGLLSGKTRILVTHGLTFLPKVDNIFVMKDGKISENGTFKELVKNNGPFAEFVRTYLEQEEEEGEVEDSEDEAKELKNELKRTISKLSSQLDNQNELQKSTISNKFLFESKKSHRRQSSVRLSKSKSVLAEEAEEQMRKAKKNKLIEDEVAETGGVKFSVFLSYLRSSTYLFSIITVVSYLLYLVCSVGANLFLSYWSESGNTSKSQN-----FYLGIYGAIGAGQGVFILIENFALAYGTFMASKSLHTLLLKSILRAPNSFFDTTPLGRILNRIGKDIDTVDVNIPTTIRMWLATAAGVFASVIVISISSPYFLIALIPLALMYYMAQRFYICTSRQLKRIDSIKRSPIYSHFQETIVGATSIRAYKVTEDFINKCDTMNDENQMAWYPNILSYRWLQLNLETIGNIVILLAGILGVLTRDTIGSGYAGLSLSYALQITGSLNFMVRMTCDLESYTVAVERIKEYADIESEAPWDNEEVKPPAEWPSSGKVEFINYSVRYRPGLELVLRNLNLCVSAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIEIDNINVSRLGLHDLRSKITIIPQDPVLFSGTLRMNLDPFNQYSDGELWSSLESSYLKSFVSKTPEGLDFIVSESGENMSVGQRQLVCLARALLKRTKVLVLDEATAAIDLETDDLIQNSIRKQFKSCTVLTIAHRLNTILDYDR 1529
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Planmine SMEST
Match: SMESG000064939.1 (SMESG000064939.1)

HSP 1 Score: 1055.05 bits (2727), Expect = 0.000e+0
Identity = 523/898 (58.24%), Postives = 667/898 (74.28%), Query Frame = 2 
Query:   41 FTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLL-SLIPDDKTI--PINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSN-YKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYL 2722
            F  LCS+KS DWLLW     W+T +PD+TLCFQYTILNWIPL+FL I C I IPIL  K S  Y  RGKFNI KS L+  + F + L+   + S+ I+ L PP A +LQPILSA+ S+L+IY+NRL Y KG+HSSG+LF YW LQL+ +  ++YSR  R+K    D FR +T+  EF++VF+SFI NCFAD  V   +   ++   D DET  LL + + DDKT+  P+    CPE + SFLSK+TF+W T L+ +G+R+PLT  DL+ L+E D+C  IV  ++ +WNRE  RV +   +++  K    +S+ Y+ L SE  E+          N  +    P FLR L HTI Y +  +G+ KV YD   F QP ILG +I FI N N+Y+WHGF    C+FL+SM R+ I QQ+   C VTG+R++TA+I IIY+KALKLS  SRKE TVGEIVNLMSVD+ K QD P F H+LW +PITI++ +YFLWQELGP+ +AG+ L+IC++PIN +IGSK+KKLQ +QM+MKD RIKL++EILSGIKILKL+AWE S E+ ++ IR  EC +LR A +LNA ++V WFC P LVAL +F A+ L+  +++LT  KAFVS+SLFNIL+FPMSMLPG IV+ IQ  VS KRIN FL G+ELD +NVEVS  ++KP+ IV+G FSWG+ EAP+L +IN+E+ EGSLV +VGTVGSGK+SLISA++GE++K+SG V  +  + Y+PQQAWC+N SLQDNILF K ++  KY++V+EACAL EDLK+LPAGDQTEIGEKGINLSGGQKQRISLAR+VYQ+ SVYL DDPLSAVD+HVGKHIF++V    GLLS  TRILVTHGL YL K DKIFVMKDGNVSESGT+ ELLKN+G FA+FIRTYL
Sbjct:    6 FKILCSNKSPDWLLWSSNAIWDTPNPDLTLCFQYTILNWIPLMFLIIGCAINIPILLRKKSIYYSTRGKFNIIKSILVCGLFFIYCLDLFKSTSDQIAGLQPPVAQFLQPILSAVFSLLVIYVNRLTYIKGVHSSGILFIYWSLQLIVNAIILYSRSIRVKTPANDKFRFITSIIEFVIVFISFIANCFADSNVIKQTLTKSS-SNDMDETHLLLPNNLNDDKTVEYPV----CPELKASFLSKITFSWPTRLIYRGFRKPLTIDDLYMLKEEDSCKEIVPIIDREWNRELDRVHRKIIKQQYLKLESTSSHRYQSLPSENMESN-----TRKTNISKDTPKPWFLRVLLHTISYKFFFSGLLKVIYDQSNFIQPAILGYYINFIGNHNEYIWHGFFYMFCIFLVSMARTFINQQFMFMCAVTGIRAKTAIISIIYKKALKLSLASRKERTVGEIVNLMSVDASKFQDFPFFFHLLWVSPITIIVTMYFLWQELGPATIAGLVLLICMLPINAVIGSKIKKLQTQQMRMKDGRIKLISEILSGIKILKLFAWELSLEEKVKTIREKECLVLRKAMFLNAFTSVAWFCTPPLVALFSFGAYVLADPNNILTPQKAFVSISLFNILNFPMSMLPGAIVFTIQGLVSAKRINHFLNGEELDPDNVEVSTSNDKPISIVNGNFSWGENEAPILRDINLEIEEGSLVMIVGTVGSGKSSLISAILGEMFKISGTVKRKEPVAYVPQQAWCQNRSLQDNILFGKSMVYSKYHKVLEACALIEDLKILPAGDQTEIGEKGINLSGGQKQRISLARSVYQNSSVYLFDDPLSAVDAHVGKHIFEKVFSSDGLLSKTTRILVTHGLAYLAKADKIFVMKDGNVSESGTYKELLKNDGPFADFIRTYL 893

HSP 2 Score: 791.956 bits (2044), Expect = 0.000e+0
Identity = 395/622 (63.50%), Postives = 483/622 (77.65%), Query Frame = 2 
Query: 2999 VAEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNR---------------------------------------IGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            VA+IGGVK  VF+ YI+  +YLF+   +  Y  Y+   V  N+ LS W+E G+ N +Q+  ++ ++LGIYG L   QA+FILI++ +LAYG FLASK+LHN++L++I+RAP+SFFDTTP GRILNR                                       IGKDIDTVDV+IP T+RIWL + S VI SI +I I+SPYF+LAL+PL+  Y+  Q+FYI TSRQL+RIDSI++SPIYSHFQESI+G SSIRAYKV+D F  KC+ +TD++QM W+  I   RW+QFYLE IGN+VILLSGV AV  R TIGSG AGLS+SYAL IT  L  MVR + D+ES+ VA+ERIKEY EIESEAPW+I E +  S+WP +G++EF N+SVRYRPGLDL LRNLN  V  GEKLGIVGRTGAGKSSLALALFRLIEPAEGTI ID+ DIT LGLHDLRSK+TIIPQDP+LFSG +R+NLDPFN +SDGE+W  LE++ LKSF A+T  GL++ +SE GENLSVGQ+QLVCLARALLKK+ +LVLDEATAAVD+ETD+LIQ+SIR  FK CTVLTIAHRLNTIMDYDRVMVL+QG++KEI++P+ LLA+EKS+FHSMA DAGLA
Sbjct:  968 VAKIGGVKLEVFIYYIQCGSYLFAMLAILCYCSYLAALVSGNIVLSSWSEAGTINNSQDLAARDYFLGIYGGLAFTQAIFILIQSLSLAYGMFLASKTLHNVMLRSIIRAPNSFFDTTPSGRILNRLEMFIVTFKRKDLHETITFLRFLSLSSHSFHEKGEEVVEIGKDIDTVDVTIPNTVRIWLTSGSRVISSIIIICIASPYFILALIPLSFFYFFIQKFYICTSRQLQRIDSIRKSPIYSHFQESIIGTSSIRAYKVTDKFTTKCEELTDKSQMVWFLIISCNRWMQFYLELIGNIVILLSGVFAVFIRDTIGSGLAGLSVSYALMITTSLAVMVRNSCDIESNVVAIERIKEYTEIESEAPWDIPEVKPPSEWPQNGKIEFSNFSVRYRPGLDLALRNLNFTVQRGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIKIDDIDITLLGLHDLRSKLTIIPQDPVLFSGNLRINLDPFNLYSDGEIWIALEIANLKSFFAQTDLGLEFTISENGENLSVGQRQLVCLARALLKKTNILVLDEATAAVDMETDELIQNSIRTAFKSCTVLTIAHRLNTIMDYDRVMVLQQGQIKEINTPKKLLADEKSLFHSMAKDAGLA 1589

HSP 3 Score: 78.1814 bits (191), Expect = 5.310e-14
Identity = 68/263 (25.86%), Postives = 117/263 (44.49%), Query Frame = 2 
Query: 3926 VAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQ---FKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            V+ +RI  +   E   P N+E S ++ D P    +  VN +  +      +LR++N+ ++ G  + IVG  G+GKSSL  A+   +    GT+               +  +  +PQ     + +++ N+         +   VLE   L   +     G Q  + E G NLS GQKQ + LAR++ + S V + D+  +AVD      I   +        K T + + H L  +   D++ V++ G V E  + + LL N+
Sbjct:  638 VSAKRINHFLNGEELDPDNVEVSTSN-DKP----ISIVNGNFSWGENEAPILRDINLEIEEGSLVMIVGTVGSGKSSLISAILGEMFKISGTV-------------KRKEPVAYVPQQAWCQNRSLQDNILFGKSMVYSKYHKVLEACALIEDLKILPAGDQTEIGEKGINLSGGQKQRISLARSVYQNSSVYLFDDPLSAVDAHVGKHIFEKVFSSDGLLSKTTRILVTHGLAYLAKADKIFVMKDGNVSESGTYKELLKND 882

HSP 4 Score: 71.2478 bits (173), Expect = 6.843e-12
Identity = 69/266 (25.94%), Postives = 115/266 (43.23%), Query Frame = 2 
Query: 1955 VSLKRINKFL-VGDELDTENVEVSPPDEKPV--KIVDGTFS--WGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            V+++RI ++  +  E   +  EV PP E P   KI    FS  +       L N+N  V  G  + +VG  G+GK+SL  AL   +    G +               R  +  IPQ     + +L+ N+       + +    +E   L         G +  I E G NLS GQ+Q + LARA+ +  ++ +LD+  +AVD    + I + +        S T + + H L  +   D++ V++ G + E  T  +LL +  S 
Sbjct: 1316 VAIERIKEYTEIESEAPWDIPEVKPPSEWPQNGKIEFSNFSVRYRPGLDLALRNLNFTVQRGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIKIDDIDITLLGLHDLRSKLTIIPQDPVLFSGNLRINLDPFNLYSDGEIWIALEIANLKSFFAQTDLGLEFTISENGENLSVGQRQLVCLARALLKKTNILVLDEATAAVDMETDELIQNSI---RTAFKSCTVLTIAHRLNTIMDYDRVMVLQQGQIKEINTPKKLLADEKSL 1578
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Planmine SMEST
Match: SMESG000064939.1 (SMESG000064939.1)

HSP 1 Score: 1055.05 bits (2727), Expect = 0.000e+0
Identity = 523/898 (58.24%), Postives = 667/898 (74.28%), Query Frame = 2 
Query:   41 FTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINNFQQDFDETQPLL-SLIPDDKTI--PINRIPCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTKFRKKLEKQNGFTSN-YKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYL 2722
            F  LCS+KS DWLLW     W+T +PD+TLCFQYTILNWIPL+FL I C I IPIL  K S  Y  RGKFNI KS L+  + F + L+   + S+ I+ L PP A +LQPILSA+ S+L+IY+NRL Y KG+HSSG+LF YW LQL+ +  ++YSR  R+K    D FR +T+  EF++VF+SFI NCFAD  V   +   ++   D DET  LL + + DDKT+  P+    CPE + SFLSK+TF+W T L+ +G+R+PLT  DL+ L+E D+C  IV  ++ +WNRE  RV +   +++  K    +S+ Y+ L SE  E+          N  +    P FLR L HTI Y +  +G+ KV YD   F QP ILG +I FI N N+Y+WHGF    C+FL+SM R+ I QQ+   C VTG+R++TA+I IIY+KALKLS  SRKE TVGEIVNLMSVD+ K QD P F H+LW +PITI++ +YFLWQELGP+ +AG+ L+IC++PIN +IGSK+KKLQ +QM+MKD RIKL++EILSGIKILKL+AWE S E+ ++ IR  EC +LR A +LNA ++V WFC P LVAL +F A+ L+  +++LT  KAFVS+SLFNIL+FPMSMLPG IV+ IQ  VS KRIN FL G+ELD +NVEVS  ++KP+ IV+G FSWG+ EAP+L +IN+E+ EGSLV +VGTVGSGK+SLISA++GE++K+SG V  +  + Y+PQQAWC+N SLQDNILF K ++  KY++V+EACAL EDLK+LPAGDQTEIGEKGINLSGGQKQRISLAR+VYQ+ SVYL DDPLSAVD+HVGKHIF++V    GLLS  TRILVTHGL YL K DKIFVMKDGNVSESGT+ ELLKN+G FA+FIRTYL
Sbjct:    6 FKILCSNKSPDWLLWSSNAIWDTPNPDLTLCFQYTILNWIPLMFLIIGCAINIPILLRKKSIYYSTRGKFNIIKSILVCGLFFIYCLDLFKSTSDQIAGLQPPVAQFLQPILSAVFSLLVIYVNRLTYIKGVHSSGILFIYWSLQLIVNAIILYSRSIRVKTPANDKFRFITSIIEFVIVFISFIANCFADSNVIKQTLTKSS-SNDMDETHLLLPNNLNDDKTVEYPV----CPELKASFLSKITFSWPTRLIYRGFRKPLTIDDLYMLKEEDSCKEIVPIIDREWNRELDRVHRKIIKQQYLKLESTSSHRYQSLPSENMESN-----TRKTNISKDTPKPWFLRVLLHTISYKFFFSGLLKVIYDQSNFIQPAILGYYINFIGNHNEYIWHGFFYMFCIFLVSMARTFINQQFMFMCAVTGIRAKTAIISIIYKKALKLSLASRKERTVGEIVNLMSVDASKFQDFPFFFHLLWVSPITIIVTMYFLWQELGPATIAGLVLLICMLPINAVIGSKIKKLQTQQMRMKDGRIKLISEILSGIKILKLFAWELSLEEKVKTIREKECLVLRKAMFLNAFTSVAWFCTPPLVALFSFGAYVLADPNNILTPQKAFVSISLFNILNFPMSMLPGAIVFTIQGLVSAKRINHFLNGEELDPDNVEVSTSNDKPISIVNGNFSWGENEAPILRDINLEIEEGSLVMIVGTVGSGKSSLISAILGEMFKISGTVKRKEPVAYVPQQAWCQNRSLQDNILFGKSMVYSKYHKVLEACALIEDLKILPAGDQTEIGEKGINLSGGQKQRISLARSVYQNSSVYLFDDPLSAVDAHVGKHIFEKVFSSDGLLSKTTRILVTHGLAYLAKADKIFVMKDGNVSESGTYKELLKNDGPFADFIRTYL 893

HSP 2 Score: 811.216 bits (2094), Expect = 0.000e+0
Identity = 395/583 (67.75%), Postives = 483/583 (82.85%), Query Frame = 2 
Query: 2999 VAEIGGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQNPDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGLA 4747
            VA+IGGVK  VF+ YI+  +YLF+   +  Y  Y+   V  N+ LS W+E G+ N +Q+  ++ ++LGIYG L   QA+FILI++ +LAYG FLASK+LHN++L++I+RAP+SFFDTTP GRILNRIGKDIDTVDV+IP T+RIWL + S VI SI +I I+SPYF+LAL+PL+  Y+  Q+FYI TSRQL+RIDSI++SPIYSHFQESI+G SSIRAYKV+D F  KC+ +TD++QM W+  I   RW+QFYLE IGN+VILLSGV AV  R TIGSG AGLS+SYAL IT  L  MVR + D+ES+ VA+ERIKEY EIESEAPW+I E +  S+WP +G++EF N+SVRYRPGLDL LRNLN  V  GEKLGIVGRTGAGKSSLALALFRLIEPAEGTI ID+ DIT LGLHDLRSK+TIIPQDP+LFSG +R+NLDPFN +SDGE+W  LE++ LKSF A+T  GL++ +SE GENLSVGQ+QLVCLARALLKK+ +LVLDEATAAVD+ETD+LIQ+SIR  FK CTVLTIAHRLNTIMDYDRVMVL+QG++KEI++P+ LLA+EKS+FHSMA DAGLA
Sbjct:  968 VAKIGGVKLEVFIYYIQCGSYLFAMLAILCYCSYLAALVSGNIVLSSWSEAGTINNSQDLAARDYFLGIYGGLAFTQAIFILIQSLSLAYGMFLASKTLHNVMLRSIIRAPNSFFDTTPSGRILNRIGKDIDTVDVTIPNTVRIWLTSGSRVISSIIIICIASPYFILALIPLSFFYFFIQKFYICTSRQLQRIDSIRKSPIYSHFQESIIGTSSIRAYKVTDKFTTKCEELTDKSQMVWFLIISCNRWMQFYLELIGNIVILLSGVFAVFIRDTIGSGLAGLSVSYALMITTSLAVMVRNSCDIESNVVAIERIKEYTEIESEAPWDIPEVKPPSEWPQNGKIEFSNFSVRYRPGLDLALRNLNFTVQRGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIKIDDIDITLLGLHDLRSKLTIIPQDPVLFSGNLRINLDPFNLYSDGEIWIALEIANLKSFFAQTDLGLEFTISENGENLSVGQRQLVCLARALLKKTNILVLDEATAAVDMETDELIQNSIRTAFKSCTVLTIAHRLNTIMDYDRVMVLQQGQIKEINTPKKLLADEKSLFHSMAKDAGLA 1550

HSP 3 Score: 78.1814 bits (191), Expect = 5.275e-14
Identity = 68/263 (25.86%), Postives = 117/263 (44.49%), Query Frame = 2 
Query: 3926 VAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQ---FKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANE 4705
            V+ +RI  +   E   P N+E S ++ D P    +  VN +  +      +LR++N+ ++ G  + IVG  G+GKSSL  A+   +    GT+               +  +  +PQ     + +++ N+         +   VLE   L   +     G Q  + E G NLS GQKQ + LAR++ + S V + D+  +AVD      I   +        K T + + H L  +   D++ V++ G V E  + + LL N+
Sbjct:  638 VSAKRINHFLNGEELDPDNVEVSTSN-DKP----ISIVNGNFSWGENEAPILRDINLEIEEGSLVMIVGTVGSGKSSLISAILGEMFKISGTV-------------KRKEPVAYVPQQAWCQNRSLQDNILFGKSMVYSKYHKVLEACALIEDLKILPAGDQTEIGEKGINLSGGQKQRISLARSVYQNSSVYLFDDPLSAVDAHVGKHIFEKVFSSDGLLSKTTRILVTHGLAYLAKADKIFVMKDGNVSESGTYKELLKND 882

HSP 4 Score: 71.2478 bits (173), Expect = 7.279e-12
Identity = 69/266 (25.94%), Postives = 115/266 (43.23%), Query Frame = 2 
Query: 1955 VSLKRINKFL-VGDELDTENVEVSPPDEKPV--KIVDGTFS--WGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMC-------------RGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSF 2698
            V+++RI ++  +  E   +  EV PP E P   KI    FS  +       L N+N  V  G  + +VG  G+GK+SL  AL   +    G +               R  +  IPQ     + +L+ N+       + +    +E   L         G +  I E G NLS GQ+Q + LARA+ +  ++ +LD+  +AVD    + I + +        S T + + H L  +   D++ V++ G + E  T  +LL +  S 
Sbjct: 1277 VAIERIKEYTEIESEAPWDIPEVKPPSEWPQNGKIEFSNFSVRYRPGLDLALRNLNFTVQRGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIKIDDIDITLLGLHDLRSKLTIIPQDPVLFSGNLRINLDPFNLYSDGEIWIALEIANLKSFFAQTDLGLEFTISENGENLSVGQRQLVCLARALLKKTNILVLDEATAAVDMETDELIQNSI---RTAFKSCTVLTIAHRLNTIMDYDRVMVLQQGQIKEINTPKKLLADEKSL 1539
[Close]
BLAST of Canalicular multispecific organic anion transporter 1 vs. Planmine SMEST
Match: SMESG000014785.1 (SMESG000014785.1)

HSP 1 Score: 631.713 bits (1628), Expect = 0.000e+0
Identity = 383/932 (41.09%), Postives = 549/932 (58.91%), Query Frame = 2 
Query:  101 WNTQDPDITLCFQYTILNWIPLLFLWISCMIYIPILWNKASFIYRNRGKFN---IFKSTLI--AFILFFHLLNFCATISESISNLYPPPALYLQPXXXXXXXXXXXXXNRLIYKKGIHSSGVLFFYWLLQLLASITVIYSRYR----RLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVFTDSEQINN---FQQ------DFDETQPLLSLIPD--------DKTIPINRI-------PCPENRVSFLSKLTFTWLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNR---ENQRVKQTKFRKKL--EKQNG--------------FTS---NYKPLKSEEEETEIDFVXXXXXXXXXXXXSPSFLRALFHTIGYPYML-AGVFKVAYDLLTFAQPQILGLFITFI-DNPNDYVWHGFLLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEKPVKIVDGTFSW-GKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYL 2722
            WN+  PDI  CFQ+     I LL   I C  YI         I+  R K N    FK T+I  A I+   +L     I  +      P A  +      +   +L  +  L  +    +SG  F YWLL  +  +  + +R      +LK  +RD  R          V +S +L+CF++    ++ E++N    FQ       D +     + + P+        +K I IN+         CPE   SFLS++ F W T L++KGY+ PL  +DL+ L   + C +IV  +   +++    N+R + +K  K L  +K N                TS   N K    +  ET+ D        K+++K  P  + AL  +  +PY+L +G++K+ +D+L F  P +L L + F+ D+   + W G+ +A  + + +M+R+ I  QY+H  +  GMR R+++I  +YRK+L+LS+ SRKE+TVGEIVNLMS+D+QK  ++ S++H++W+ P  I+ A+  LW ELGPSVLAG+ +M+ +IP+N +IG+  +K+QA+Q+K+ D+RIK+MNEIL+GIK+LKLYAWE SF   +  IRN E + ++ A Y NA  + T+ CAPFLV+L TF  F L S  +VL A KAFVS++LFNIL FP+ MLP VI   IQA VSLKR+  FL  +E++ + V           I +G F W   T  PVL NIN+  PE  LVA+VG VG GK+S++SAL+GE+ K+ G V  +GSI Y+PQQAW  NA+++DNI+F  P    KY R+I+AC L  D ++L   D TEIGEKGINLSGGQKQR+SLARA Y D +VYLLDDPLSAVDSHVGK + D VI  +G+L+  TRILVTH L  L K D+I VM +G VSE GT+++L+++ G+FA FI T+L
Sbjct:    9 WNSPSPDIPTCFQF-FDAPIYLLGYLILCFPYI---------IHLIRKKVNERPFFKLTIIKLALIVCLMVLQILEIIYNAAKKNNIPYAYTISNCSFLVCMSILAIMVGLERRCNAVNSGFYFNYWLLHFI--LCAVRARASGLSLKLKITNRDYSRECFIFINLTFVTLSLVLSCFSEKVSQSEIERLNKKRKFQNVLHVNADDNHVSDRMEMSPNAVDSYKTTEKDILINKTDGNVDLKECPEYYSSFLSRIIFFWFTPLIVKGYKIPLKNEDLWVLNTEERCSSIVPILLRNFDKCLAPNKR-RDSKSDKMLTNDKNNSGKKYKEIEEPEKEKLTSPPDNNKRSIPQNAETDTD--------KKKEKFDPCLMNALIKS-HFPYLLLSGLYKIIHDILAFLGPILLKLLLQFVSDSEERHYWKGYFIAALMMISAMVRTFILHQYFHIVFKIGMRVRSSLISAVYRKSLRLSTASRKESTVGEIVNLMSIDAQKFLELISYIHMIWSGPYQIIAALILLWYELGPSVLAGLVIMLLMIPVNAVIGNITRKIQAQQIKVTDSRIKMMNEILNGIKVLKLYAWEPSFINFVTEIRNKELKFMKRAAYYNAAISFTFNCAPFLVSLTTFGMFVLISRDNVLDAEKAFVSITLFNILRFPLMMLPMVISNLIQASVSLKRLTTFLRREEINKDAVSHDDTPGIAATIKNGIFKWDSTTPEPVLKNINITFPERHLVAIVGPVGCGKSSILSALLGEIDKLEGYVNMKGSIAYVPQQAWIINATIRDNIIFGLPYDACKYQRIIKACCLERDFEILNDADFTEIGEKGINLSGGQKQRVSLARACYSDSNVYLLDDPLSAVDSHVGKDLIDNVISSTGILNGNTRILVTHNLAILSKCDRIIVMNNGMVSEEGTYSDLIRHAGAFANFIATHL 918

HSP 2 Score: 582.022 bits (1499), Expect = 2.696e-179
Identity = 289/605 (47.77%), Postives = 417/605 (68.93%), Query Frame = 2 
Query: 3011 GGVKFSVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETG--------------STNGTQNP---------DSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILRAPSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTAXXXXXXXXXXXXXXPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQESIVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGNLVILLSGVLAVVTRST---IGSGYAGLSISYALQITGGLNYMVRMTSDLESHTVAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDLVLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKT-SEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEIDSPQNLLANEKSIFHSMAVDAGL 4744
            G VK +V+++Y+RS  +  +  ++  +      S+G+N++L  W++                + N +Q           D +   LGIYG  G  QAL  L  +   A+    ++ SLH LLL  +LR P S F+T P+GRI+NR   D++ V   +P  I  +L+T    I    +++I +P+ ++ L  + A Y + QR Y+ TSRQLKR++S+ +SPIYSHF E++ G SSIRAY + D FI+  D   D+N  ++Y N VS RWL   LET+GN ++ ++ + AV++      I +G  GLS+SYAL IT  LN++VRM+S++ES+ V+VERI+EY+++  EAPW+I E +   +WP  G ++FVNYS +YR GLD VL+N+N +++  EK+GIVGRTG+GKSSL LALFR++E ++G I+ID   I +LGLHD+R ++TIIPQDP+LFSGT+R NLDPFN+H D E+W VLEMS LK+F+  + +E L+ ++SEGGENLSVGQ+QLVCLARALL+++ +LVLDEATAAVDL+TD LIQ +IRR+FK+CT+LTIAHRLNT++DYD+++VLE G + E+D+P NLL N +S F+SMA  + L
Sbjct: 1025 GNVKMAVYMAYLRSIGFWLAAGIILLFVTTQGFSLGSNLWLVRWSDQSKIAANLSKELKELIAHNSSQKQIDDLRKIIRDQRDLNLGIYGVFGFCQALIQLFSSLFFAFAIIKSAASLHKLLLNGVLRCPMSMFETVPVGRIINRFSSDLNAVGTMLPHFINGFLVTTLQAIVVFIMVTIPNPWIIIPLSLMIAFYILIQRVYVSTSRQLKRLESVVKSPIYSHFGETLQGVSSIRAYSLCDKFIESNDNKVDKNLYSYYANTVSNRWLAIILETVGNSIVFMAALFAVISLQNGTGINAGLVGLSVSYALSITQTLNWLVRMSSEVESNIVSVERIEEYSQMPPEAPWDISEKKPDENWP-VGCIKFVNYSTKYREGLDNVLKNINFIINPREKVGIVGRTGSGKSSLVLALFRILEKSDGEILIDGLPIHELGLHDVRGRLTIIPQDPVLFSGTLRRNLDPFNKHGDEEIWKVLEMSNLKTFVVNSGNEQLEMVISEGGENLSVGQRQLVCLARALLRRTNILVLDEATAAVDLDTDVLIQETIRREFKECTILTIAHRLNTVLDYDQILVLENGEIIEMDAPNNLLKNPESQFYSMAKSSNL 1628

HSP 3 Score: 78.9518 bits (193), Expect = 3.418e-14
Identity = 121/527 (22.96%), Postives = 219/527 (41.56%), Query Frame = 2 
Query: 1217 LLAICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKETTVGEIVNLMSVDSQKLQDV-PSFLHVLWTAPITIVIAIYFLWQELGPSVLAGVALMICL-IPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKLYAWENSFEQNIQNIRNDECRILRS--ATYLNAVSAVTWFCA---------PFLVALCTFTAFTLSSSSHVLTANKAFVSLSLFNILSFPMSM--LPGVIVYGIQAYVSLKRINKFLVGDELDTENVEVSPPDEK-PV---KIVDGTFSWGKTEAPVLININMEVPEGSLVAVVGTVGSGKTSLISALIGELYKVSGRVM-------------CRGSIGYIPQQAWCRNASLQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTE-----IGEKGINLSGGQKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKTRILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKN 2686
            +   C  LI +  S+ F           ++S  ++  ++    L+   +  +   VG I+N  S D   +  + P F++      +   I ++ +     P ++  ++LMI   I I  +  S  ++L+  +  +K        E L G+  ++ Y+  + F      I +++ ++ ++  + Y N VS   W             F+ AL  F   +L + + +   N   V LS+   LS   ++  L  +        VS++RI ++         ++    PDE  PV   K V+ +  + +    VL NIN  +     V +VG  GSGK+SL+ AL   L K  G ++              RG +  IPQ     + +L+ N+    P   H    + +   ++ +LK        E     I E G NLS GQ+Q + LARA+ +  ++ +LD+  +AVD      I + +          T + + H L  +   D+I V+++G + E      LLKN
Sbjct: 1115 VFGFCQALIQLFSSLFFA-------FAIIKSAASLHKLLLNGVLRCPMSMFETVPVGRIINRFSSDLNAVGTMLPHFINGFLVTTLQ-AIVVFIMVTIPNPWIIIPLSLMIAFYILIQRVYVSTSRQLKRLESVVKSPIYSHFGETLQGVSSIRAYSLCDKF------IESNDNKVDKNLYSYYANTVSN-RWLAIILETVGNSIVFMAAL--FAVISLQNGTGI---NAGLVGLSVSYALSITQTLNWLVRMSSEVESNIVSVERIEEYSQMPPEAPWDISEKKPDENWPVGCIKFVNYSTKYREGLDNVLKNINFIINPREKVGIVGRTGSGKSSLVLALFRILEKSDGEILIDGLPIHELGLHDVRGRLTIIPQDPVLFSGTLRRNL---DPFNKHGDEEIWKVLEMS-NLKTFVVNSGNEQLEMVISEGGENLSVGQRQLVCLARALLRRTNILVLDEATAAVDLDTDVLIQETI---RREFKECTILTIAHRLNTVLDYDQILVLENGEIIEMDAPNNLLKN 1614

HSP 4 Score: 73.559 bits (179), Expect = 1.329e-12
Identity = 60/202 (29.70%), Postives = 92/202 (45.54%), Query Frame = 2 
Query: 4076 VLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDITKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYLKSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATAAVDLET-DDLIQSSIRRQ--FKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKE 4672
            VL+N+NI       + IVG  G GKSS+  AL   I+  EG +             +++  I  +PQ   + + TIR N+     +   +   +++   L+      ++     + E G NLS GQKQ V LARA    S V +LD+  +AVD     DLI + I         T + + H L  +   DR++V+  G V E
Sbjct:  708 VLKNINITFPERHLVAIVGPVGCGKSSILSALLGEIDKLEGYV-------------NMKGSIAYVPQQAWIINATIRDNIIFGLPYDACKYQRIIKACCLERDFEILNDADFTEIGEKGINLSGGQKQRVSLARACYSDSNVYLLDDPLSAVDSHVGKDLIDNVISSTGILNGNTRILVTHNLAILSKCDRIIVMNNGMVSE 896
The following BLAST results are available for this feature:
BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ABCC34.911e-4443.19ATP binding cassette subfamily C member 3 [Source:... [more]
ABCC36.478e-1443.19ATP binding cassette subfamily C member 3 [Source:... [more]
ABCC15.958e-1442.30ATP binding cassette subfamily C member 1 [Source:... [more]
ABCC15.958e-1442.30ATP binding cassette subfamily C member 1 [Source:... [more]
ABCC11.585e-1344.77ATP binding cassette subfamily C member 1 [Source:... [more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mrp-15.331e-1238.63pep chromosome:WBcel235:X:576318:587483:-1 gene:WB... [more]
mrp-15.522e-18038.63pep chromosome:WBcel235:X:576318:587483:-1 gene:WB... [more]
mrp-14.183e-17938.63pep chromosome:WBcel235:X:576318:587483:-1 gene:WB... [more]
mrp-16.867e-1238.63pep chromosome:WBcel235:X:576318:587483:-1 gene:WB... [more]
mrp-13.397e-17838.63pep chromosome:WBcel235:X:576318:587483:-1 gene:WB... [more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MRP1.274e-1443.54gene:FBgn0032456 transcript:FBtr0090029[more]
MRP1.421e-1443.54gene:FBgn0032456 transcript:FBtr0090021[more]
MRP1.340e-1443.54gene:FBgn0032456 transcript:FBtr0090022[more]
MRP1.409e-1443.54gene:FBgn0032456 transcript:FBtr0090026[more]
MRP1.170e-1443.54gene:FBgn0032456 transcript:FBtr0090023[more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abcc11.771e-1344.95ATP-binding cassette, sub-family C (CFTR/MRP), mem... [more]
abcc11.207e-1344.55ATP-binding cassette, sub-family C (CFTR/MRP), mem... [more]
abcc14.707e-7243.50ATP-binding cassette, sub-family C (CFTR/MRP), mem... [more]
abcc36.094e-1845.30ATP-binding cassette, sub-family C (CFTR/MRP), mem... [more]
abcc6a1.067e-17542.58ATP-binding cassette, sub-family C (CFTR/MRP), mem... [more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
septin98.258e-1747.07septin 9 [Source:Xenbase;Acc:XB-GENE-1012202][more]
septin95.137e-1946.49septin 9 [Source:Xenbase;Acc:XB-GENE-1012202][more]
septin92.552e-1646.72septin 9 [Source:Xenbase;Acc:XB-GENE-1012202][more]
septin91.021e-1646.11septin 9 [Source:Xenbase;Acc:XB-GENE-1012202][more]
ABCC17.999e-1444.30ATP binding cassette subfamily C member 1 [Source:... [more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Abcc16.783e-1443.46ATP-binding cassette, sub-family C (CFTR/MRP), mem... [more]
Abcc33.915e-1443.21ATP-binding cassette, sub-family C (CFTR/MRP), mem... [more]
Abcc33.753e-1443.21ATP-binding cassette, sub-family C (CFTR/MRP), mem... [more]
Abcc29.387e-17039.54ATP-binding cassette, sub-family C (CFTR/MRP), mem... [more]
Abcc61.962e-15235.32ATP-binding cassette, sub-family C (CFTR/MRP), mem... [more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5F364|MRP1_CHICK2.112e-1244.81Multidrug resistance-associated protein 1 OS=Gallu... [more]
sp|Q8CG09|MRP1_RAT2.357e-1343.49Multidrug resistance-associated protein 1 OS=Rattu... [more]
sp|O35379|MRP1_MOUSE4.745e-1343.46Multidrug resistance-associated protein 1 OS=Mus m... [more]
sp|Q864R9|MRP1_MACFA2.356e-1342.52Multidrug resistance-associated protein 1 OS=Macac... [more]
sp|O15438|MRP3_HUMAN3.111e-1343.19Canalicular multispecific organic anion transporte... [more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267GTI50.000e+053.18Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A2A3EBU10.000e+049.60Multidrug resistance-associated protein OS=Apis ce... [more]
A0A1I8GQF29.342e-1150.22Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8HV067.825e-1150.22Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A452I2X51.491e-1045.83ATP binding cassette subfamily C member 1 OS=Gophe... [more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abcc34.755e-2044.64ATP binding cassette subfamily C member 3 [Source:... [more]
abcc34.837e-2044.64ATP binding cassette subfamily C member 3 [Source:... [more]
abcc14.729e-1342.90ATP binding cassette subfamily C member 1 [Source:... [more]
abcc14.741e-1342.90ATP binding cassette subfamily C member 1 [Source:... [more]
abcc15.017e-1342.90ATP binding cassette subfamily C member 1 [Source:... [more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abcc37.745e-17841.53ATP-binding cassette, sub-family C (CFTR/MRP), mem... [more]
ENSPMAT00000007076.14.626e-14145.11pep scaffold:Pmarinus_7.0:GL480539:10051:22495:1 g... [more]
ENSPMAT00000006454.11.729e-13644.49pep scaffold:Pmarinus_7.0:GL483531:32:7621:1 gene:... [more]
ENSPMAT00000001536.13.083e-12339.57pep scaffold:Pmarinus_7.0:GL479104:2125:31869:1 ge... [more]
ABCC81.009e-10837.82ATP binding cassette subfamily C member 8 [Source:... [more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
YCF11.122e-17149.66Vacuolar glutathione S-conjugate transporter; ABC-... [more]
BPT11.105e-12841.16ABC type transmembrane transporter of MRP/CFTR fam... [more]
YBT11.120e-11940.39Transporter of the ATP-binding cassette (ABC) fami... [more]
VMR13.566e-11739.71Vacuolar membrane protein; involved in multiple dr... [more]
YOR11.656e-11637.48Plasma membrane ATP-binding cassette (ABC) transpo... [more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO364746.503e-1551.97Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO350711.798e-17450.76Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO434339.374e-15356.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO316473.328e-14242.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO352501.230e-13641.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abcc15.988e-1444.77multidrug resistance-associated protein 1 [Source:... [more]
abcc16.450e-16944.62multidrug resistance-associated protein 1 [Source:... [more]
abcc31.488e-2044.91ATP binding cassette subfamily C member 3 [Source:... [more]
abcc11.382e-16845.07multidrug resistance-associated protein 1 [Source:... [more]
abcc16.320e-16945.07multidrug resistance-associated protein 1 [Source:... [more]
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BLAST of Canalicular multispecific organic anion transporter 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000057252.10.000e+099.87SMESG000057252.1[more]
SMESG000039911.10.000e+074.17SMESG000039911.1[more]
SMESG000064939.15.310e-1458.24SMESG000064939.1[more]
SMESG000064939.15.275e-1458.24SMESG000064939.1[more]
SMESG000014785.12.696e-17941.09SMESG000014785.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30000258 ID=SMED30000258|Name=Canalicular multispecific organic anion transporter 1|organism=Schmidtea mediterranea sexual|type=transcript|length=4827bp
CTAATTAATATTGGAATTGAAAAAAATGGGGAAATCACATTTTACCAGTC
TGTGTTCCGACAAATCTAACGACTGGCTATTATGGTATGATTTGATTGGA
TGGAATACGCAAGATCCTGATATAACTCTCTGTTTCCAATATACAATTTT
GAACTGGATCCCATTATTATTTTTATGGATTAGTTGCATGATATACATTC
CCATATTGTGGAATAAAGCAAGTTTTATTTATAGGAACCGAGGAAAGTTT
AATATATTTAAATCGACATTAATAGCTTTCATTTTATTTTTTCATCTTTT
AAATTTTTGTGCAACAATTAGTGAAAGCATCAGCAATTTATACCCTCCAC
CAGCCCTGTACCTCCAACCAATATTATCAGCAATATCATCAATTTTACTA
ATTTATCTAAACCGGCTCATATATAAGAAAGGAATTCATTCATCGGGAGT
ATTATTTTTTTATTGGTTACTCCAATTACTCGCTAGTATTACCGTTATAT
ATTCTAGATACAGAAGACTCAAATTTCACGATAGAGACTTATTTCGAACT
GTAACAGCGACATTCGAGTTTCTTCTTGTTTTCGTCAGTTTCATTTTGAA
TTGTTTTGCCGATCTGGCAGTTTTTACAGATTCCGAGCAAATAAATAACT
TTCAACAGGACTTTGATGAGACTCAACCACTCTTAAGTTTGATTCCGGAC
GACAAAACTATTCCTATTAATCGAATACCTTGCCCAGAAAACCGAGTCTC
ATTTCTATCCAAATTGACATTTACATGGCTAACGGGACTCGTTATTAAAG
GTTATCGGCAACCCCTGACCTTCAAAGACCTGTTTGCGCTACGTGAAAAT
GATACTTGTGATACAATAGTCACCAATATGGAATTTCAGTGGAACCGGGA
AAATCAAAGAGTCAAACAAACAAAATTTCGTAAGAAACTGGAAAAACAAA
ATGGATTCACCAGTAATTATAAACCTTTGAAGTCTGAAGAGGAAGAAACA
GAAATAGATTTTGTTCAAAACACAAACAACAATAAGGAACAAAAGAAAAA
ATCTCCGTCATTTTTACGAGCACTCTTTCATACAATTGGATATCCATATA
TGCTAGCGGGAGTCTTTAAAGTTGCATATGACCTATTAACCTTTGCTCAG
CCTCAAATTTTAGGGCTGTTCATTACTTTTATTGACAACCCGAATGATTA
CGTTTGGCATGGATTTTTATTAGCGATATGTCTTTTTTTGATATCAATGA
TCCGATCAGTTATCTTTCAGCAATATTATCATGGCTGTTACGTCACTGGA
ATGAGGTCAAGGACAGCAGTCATTGGAATTATTTACAGAAAGGCCTTAAA
ACTTTCCTCGACCAGCCGCAAAGAAACTACAGTAGGTGAAATAGTCAACC
TCATGTCAGTTGATTCACAAAAATTGCAAGATGTACCGAGTTTTTTACAC
GTTTTGTGGACCGCTCCAATAACAATTGTGATAGCCATTTATTTTTTATG
GCAAGAATTAGGACCGTCAGTGTTAGCTGGAGTGGCTTTAATGATCTGTT
TAATTCCAATTAATGGAATAATAGGATCTAAAGTGAAAAAACTTCAAGCT
AAACAAATGAAAATGAAAGATAACCGAATTAAACTAATGAATGAAATACT
GAGTGGAATAAAGATTCTAAAATTATATGCTTGGGAAAATTCTTTTGAGC
AAAATATTCAAAATATTAGAAATGATGAATGCCGGATTCTTCGTTCTGCA
ACCTATTTAAATGCAGTTAGTGCTGTAACTTGGTTCTGTGCACCGTTCCT
CGTCGCCCTCTGTACCTTTACCGCATTCACTTTATCCAGTTCTAGTCACG
TTTTGACTGCTAACAAGGCTTTTGTGTCATTATCTCTATTTAATATCCTT
AGCTTTCCGATGTCTATGTTGCCAGGTGTCATAGTATATGGCATACAGGC
TTATGTTTCATTAAAAAGAATAAATAAATTTCTAGTTGGAGATGAATTGG
ATACTGAAAACGTTGAAGTCTCTCCTCCGGATGAAAAACCTGTAAAAATA
GTTGATGGAACTTTTAGCTGGGGTAAAACTGAAGCTCCAGTCTTAATTAA
TATAAATATGGAAGTACCGGAAGGAAGTCTTGTAGCAGTGGTTGGTACCG
TGGGAAGTGGGAAAACCTCATTAATCAGTGCATTAATTGGTGAATTGTAT
AAAGTTTCAGGCAGAGTCATGTGCAGAGGATCAATTGGTTATATTCCTCA
ACAAGCTTGGTGTCGAAATGCATCTCTTCAGGATAATATTTTATTTAGCA
AACCACTGATAAATCACAAATACAATCGGGTCATTGAGGCTTGCGCATTG
ACAGAGGATCTTAAAGTTCTTCCTGCTGGTGATCAAACAGAAATAGGGGA
AAAAGGTATAAATCTATCAGGGGGTCAGAAACAAAGAATAAGTTTAGCAA
GGGCCGTATACCAAGATTGTTCTGTATATTTACTTGATGATCCTTTGTCA
GCTGTTGATTCTCATGTTGGAAAGCATATATTTGACCAGGTCATCGGGCC
AAGTGGGTTACTGTCTAGTAAAACTCGTATTTTAGTTACTCATGGACTGA
CATACTTACCGAAGGTTGATAAAATATTTGTCATGAAAGATGGAAATGTA
AGTGAAAGTGGAACTTTCACAGAACTTTTAAAAAATAACGGTTCTTTCGC
TGAATTTATACGAACTTATCTTGAACAGGAAGAAGAAGAAAATGTCGAAG
AAGATAGTGAAGATGAATCAAAAGAACTTAAGAAAGAACTGAAACATACC
ATATCAAGGTTGTCATCTAATATTGACAGTGAATCCGAATACCAGAAATC
TAGTCATAGTAGCAATCCTTTGACCGATTCACGGAGAAGCCACAAACGTC
AATCAAGTGTTCGGTTATCTAAGAGTCGAAGTGTTTTAGCTGAGGAAGCT
GAAGCAGAATTAAAGAAGGCTAAAAAGAAAAGGCTCATTGAAGAAGAAGT
AGCAGAAATTGGAGGAGTTAAATTTTCTGTGTTTTTGTCCTATATTCGAT
CATCAACATATTTGTTTTCATTTACCGTTGTATTTTCTTATGCACTTTAT
ATGTGCTGTTCAGTTGGAGCGAACATGTTCTTGAGTTATTGGACGGAAAC
TGGTAGCACTAATGGAACTCAGAACCCCGATAGTCAAGGATTTTACTTGG
GAATATATGGCAGTTTAGGAGCTGGTCAAGCATTATTTATTCTTATTGAA
AATTTTGCACTTGCTTATGGAACATTTTTGGCATCGAAATCCTTGCACAA
TTTATTATTGAAAAATATCTTACGAGCACCGAGTTCATTTTTTGATACTA
CTCCTCTCGGAAGAATATTGAATAGAATCGGTAAAGATATTGACACGGTG
GATGTAAGCATTCCTACGACCATCAGAATTTGGTTAATGACAGCGTCAGG
GGTCATCGGCTCAATTTTCGTCATCAGTATTTCATCGCCATACTTTTTGC
TGGCTCTAGTCCCACTAACTGCCATGTATTATATGGCGCAGAGATTCTAT
ATTTACACCAGTCGACAGCTGAAAAGAATTGACTCAATAAAGAGATCGCC
AATCTATTCACATTTCCAAGAGAGTATTGTAGGAGCTTCGTCAATTAGAG
CATATAAAGTTTCTGATGACTTTATAAAAAAATGTGACATCATGACCGAC
GAAAATCAAATGGCGTGGTACCCAAATATTGTTTCATATCGATGGTTGCA
ATTTTATCTGGAAACTATAGGAAACCTTGTTATCTTATTATCTGGGGTTC
TGGCAGTCGTAACAAGATCTACAATTGGGAGTGGGTATGCAGGTTTGAGT
ATCAGTTACGCGTTACAGATAACTGGAGGTCTGAATTATATGGTACGAAT
GACTAGTGATCTTGAATCACACACTGTTGCTGTTGAAAGAATCAAAGAAT
ACGCGGAAATAGAATCGGAAGCGCCTTGGAATATCGAAGAGTCTCAAGCG
CATTCAGATTGGCCTGATAGTGGAAGGGTAGAATTCGTAAATTATTCAGT
GAGATATCGTCCGGGTCTTGATTTGGTTTTAAGAAATTTAAATATAGTTG
TCGATGCTGGTGAAAAATTGGGTATCGTTGGAAGAACCGGTGCTGGAAAG
TCGTCTTTGGCGTTGGCTTTGTTTAGACTGATCGAACCTGCAGAAGGTAC
TATAATCATTGACAATCGAGACATTACTAAATTGGGATTACATGATTTGA
GAAGTAAAATAACAATTATTCCTCAGGATCCTATTTTGTTTTCCGGGACA
ATTAGAATGAATCTTGATCCATTTAATCAACACTCAGACGGAGAATTATG
GAGTGTATTGGAAATGTCTTACTTAAAATCCTTTATTGCAAAGACAAGCG
AGGGTCTACAATATCTGGTCTCTGAAGGTGGGGAAAACCTGAGTGTTGGT
CAAAAACAATTAGTTTGCTTAGCAAGAGCCTTGCTAAAAAAGTCGAAGGT
TCTAGTTCTTGACGAAGCAACTGCGGCGGTTGATTTGGAAACCGATGATT
TGATTCAAAGTAGCATTCGACGTCAGTTTAAAAAATGTACAGTTTTAACA
ATTGCACATCGTCTAAATACAATCATGGATTATGACAGGGTTATGGTTCT
AGAACAGGGTAGGGTTAAGGAAATAGACTCCCCTCAAAATTTATTGGCCA
ACGAGAAGTCAATATTTCACAGCATGGCAGTGGACGCTGGTTTGGCGTGA
AAATAAACATTCACATTTATCAATTTTCAGTTTCTAGAAAATATATAAAT
TGACTTTTTAAAAAAAAAGATCGGAAG
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protein sequence of SMED30000258-orf-1

>SMED30000258-orf-1 ID=SMED30000258-orf-1|Name=SMED30000258-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1575bp
MGKSHFTSLCSDKSNDWLLWYDLIGWNTQDPDITLCFQYTILNWIPLLFL
WISCMIYIPILWNKASFIYRNRGKFNIFKSTLIAFILFFHLLNFCATISE
SISNLYPPPALYLQPILSAISSILLIYLNRLIYKKGIHSSGVLFFYWLLQ
LLASITVIYSRYRRLKFHDRDLFRTVTATFEFLLVFVSFILNCFADLAVF
TDSEQINNFQQDFDETQPLLSLIPDDKTIPINRIPCPENRVSFLSKLTFT
WLTGLVIKGYRQPLTFKDLFALRENDTCDTIVTNMEFQWNRENQRVKQTK
FRKKLEKQNGFTSNYKPLKSEEEETEIDFVQNTNNNKEQKKKSPSFLRAL
FHTIGYPYMLAGVFKVAYDLLTFAQPQILGLFITFIDNPNDYVWHGFLLA
ICLFLISMIRSVIFQQYYHGCYVTGMRSRTAVIGIIYRKALKLSSTSRKE
TTVGEIVNLMSVDSQKLQDVPSFLHVLWTAPITIVIAIYFLWQELGPSVL
AGVALMICLIPINGIIGSKVKKLQAKQMKMKDNRIKLMNEILSGIKILKL
YAWENSFEQNIQNIRNDECRILRSATYLNAVSAVTWFCAPFLVALCTFTA
FTLSSSSHVLTANKAFVSLSLFNILSFPMSMLPGVIVYGIQAYVSLKRIN
KFLVGDELDTENVEVSPPDEKPVKIVDGTFSWGKTEAPVLININMEVPEG
SLVAVVGTVGSGKTSLISALIGELYKVSGRVMCRGSIGYIPQQAWCRNAS
LQDNILFSKPLINHKYNRVIEACALTEDLKVLPAGDQTEIGEKGINLSGG
QKQRISLARAVYQDCSVYLLDDPLSAVDSHVGKHIFDQVIGPSGLLSSKT
RILVTHGLTYLPKVDKIFVMKDGNVSESGTFTELLKNNGSFAEFIRTYLE
QEEEENVEEDSEDESKELKKELKHTISRLSSNIDSESEYQKSSHSSNPLT
DSRRSHKRQSSVRLSKSRSVLAEEAEAELKKAKKKRLIEEEVAEIGGVKF
SVFLSYIRSSTYLFSFTVVFSYALYMCCSVGANMFLSYWTETGSTNGTQN
PDSQGFYLGIYGSLGAGQALFILIENFALAYGTFLASKSLHNLLLKNILR
APSSFFDTTPLGRILNRIGKDIDTVDVSIPTTIRIWLMTASGVIGSIFVI
SISSPYFLLALVPLTAMYYMAQRFYIYTSRQLKRIDSIKRSPIYSHFQES
IVGASSIRAYKVSDDFIKKCDIMTDENQMAWYPNIVSYRWLQFYLETIGN
LVILLSGVLAVVTRSTIGSGYAGLSISYALQITGGLNYMVRMTSDLESHT
VAVERIKEYAEIESEAPWNIEESQAHSDWPDSGRVEFVNYSVRYRPGLDL
VLRNLNIVVDAGEKLGIVGRTGAGKSSLALALFRLIEPAEGTIIIDNRDI
TKLGLHDLRSKITIIPQDPILFSGTIRMNLDPFNQHSDGELWSVLEMSYL
KSFIAKTSEGLQYLVSEGGENLSVGQKQLVCLARALLKKSKVLVLDEATA
AVDLETDDLIQSSIRRQFKKCTVLTIAHRLNTIMDYDRVMVLEQGRVKEI
DSPQNLLANEKSIFHSMAVDAGLA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016324apical plasma membrane
GO:0016021integral component of membrane
GO:0005886plasma membrane
GO:0005887integral component of plasma membrane
GO:0016020membrane
GO:0016323basolateral plasma membrane
Vocabulary: molecular function
TermDefinition
GO:0022857transmembrane transporter activity
GO:0005524ATP binding
GO:0042626ATPase activity, coupled to transmembrane movement of substances
GO:0016887ATPase activity
GO:0000166nucleotide binding
GO:0005215transporter activity
GO:0008514organic anion transmembrane transporter activity
GO:0008559xenobiotic-transporting ATPase activity
GO:0015432bile acid-exporting ATPase activity
GO:0043225ATPase-coupled anion transmembrane transporter activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR005292Multidrug-R_assoc
IPR036640ABC1_TM_sf
IPR003593AAA+_ATPase
IPR027417P-loop_NTPase
IPR011527ABC1_TM_dom
IPR003439ABC_transporter-like
IPR017871ABC_transporter_CS
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0055085transmembrane transport
GO:0006855drug transmembrane transport
GO:0015721bile acid and bile salt transport
GO:0042908xenobiotic transport
GO:0099133ATP hydrolysis coupled anion transmembrane transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 977..999
NoneNo IPR availableCOILSCoilCoilcoord: 327..347
NoneNo IPR availableCOILSCoilCoilcoord: 908..935
NoneNo IPR availableCOILSCoilCoilcoord: 527..547
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 1325..1578
e-value: 9.8E-87
score: 292.5
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 662..931
e-value: 4.2E-71
score: 241.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 939..973
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 939..956
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 909..928
NoneNo IPR availablePANTHERPTHR24223FAMILY NOT NAMEDcoord: 78..1581
NoneNo IPR availablePANTHERPTHR24223:SF350CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 2coord: 78..1581
NoneNo IPR availableCDDcd03244ABCC_MRP_domain2coord: 1340..1560
e-value: 3.47053E-133
score: 409.191
NoneNo IPR availableCDDcd18603ABC_6TM_MRP1_2_3_6_D2_likecoord: 1022..1317
e-value: 2.23031E-148
score: 453.474
NoneNo IPR availableCDDcd03250ABCC_MRP_domain1coord: 680..880
e-value: 1.24689E-108
score: 340.986
NoneNo IPR availableCDDcd18595ABC_6TM_MRP1_2_3_6_D1_likecoord: 367..656
e-value: 1.58012E-158
score: 480.044
NoneNo IPR availableTMHMMTMhelixcoord: 399..421
NoneNo IPR availableTMHMMTMhelixcoord: 143..165
NoneNo IPR availableTMHMMTMhelixcoord: 47..69
NoneNo IPR availableTMHMMTMhelixcoord: 1274..1296
NoneNo IPR availableTMHMMTMhelixcoord: 357..379
NoneNo IPR availableTMHMMTMhelixcoord: 1025..1047
NoneNo IPR availableTMHMMTMhelixcoord: 82..104
NoneNo IPR availableTMHMMTMhelixcoord: 587..609
NoneNo IPR availableTMHMMTMhelixcoord: 1247..1269
NoneNo IPR availableTMHMMTMhelixcoord: 624..646
NoneNo IPR availableTMHMMTMhelixcoord: 1062..1081
NoneNo IPR availableTMHMMTMhelixcoord: 477..499
NoneNo IPR availableTMHMMTMhelixcoord: 119..136
NoneNo IPR availableTMHMMTMhelixcoord: 1149..1171
NoneNo IPR availableTMHMMTMhelixcoord: 185..207
NoneNo IPR availableTMHMMTMhelixcoord: 503..525
IPR003593AAA+ ATPase domainSMARTSM00382AAA_5coord: 706..881
e-value: 3.6E-10
score: 49.8
coord: 1368..1553
e-value: 3.2E-14
score: 63.3
IPR005292Multi drug resistance-associated proteinTIGRFAMTIGR00957TIGR00957coord: 17..1580
e-value: 0.0
score: 1770.9
IPR003439ABC transporter-likePFAMPF00005ABC_trancoord: 699..831
e-value: 1.5E-19
score: 70.9
IPR003439ABC transporter-likePFAMPF00005ABC_trancoord: 1359..1507
e-value: 3.1E-30
score: 105.5
IPR003439ABC transporter-likePROSITEPS50893ABC_TRANSPORTER_2coord: 1342..1576
score: 19.348
IPR003439ABC transporter-likePROSITEPS50893ABC_TRANSPORTER_2coord: 680..904
score: 22.269
IPR036640ABC transporter type 1, transmembrane domain superfamilyGENE3DG3DSA:1.20.1560.10coord: 334..661
e-value: 1.5E-22
score: 82.2
coord: 984..1324
e-value: 6.1E-43
score: 149.2
IPR036640ABC transporter type 1, transmembrane domain superfamilySUPERFAMILYSSF90123ABC transporter transmembrane regioncoord: 349..668
IPR036640ABC transporter type 1, transmembrane domain superfamilySUPERFAMILYSSF90123ABC transporter transmembrane regioncoord: 1010..1324
IPR011527ABC transporter type 1, transmembrane domainPFAMPF00664ABC_membranecoord: 1026..1291
e-value: 3.5E-40
score: 138.4
coord: 367..636
e-value: 2.5E-39
score: 135.6
IPR011527ABC transporter type 1, transmembrane domainPROSITEPS50929ABC_TM1Fcoord: 1023..1305
score: 35.948
IPR011527ABC transporter type 1, transmembrane domainPROSITEPS50929ABC_TM1Fcoord: 367..648
score: 37.783
IPR017871ABC transporter, conserved sitePROSITEPS00211ABC_TRANSPORTER_1coord: 1479..1493
IPR017871ABC transporter, conserved sitePROSITEPS00211ABC_TRANSPORTER_1coord: 804..818
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 674..904
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 1333..1568