WW domain-binding protein 4

Overview
NameWW domain-binding protein 4
Smed IDSMED30000225
Length (bp)760
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of WW domain-binding protein 4 (SMED30000225) t-SNE clustered cells

Violin plots show distribution of expression levels for WW domain-binding protein 4 (SMED30000225) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of WW domain-binding protein 4 (SMED30000225) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for WW domain-binding protein 4 (SMED30000225) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30000225

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30000225SMESG000011434.1 SmedASXL_011251SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30000225SMESG000011434.1 SmedASXL_011251SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30000225SMESG000011434.1 dd_Smed_v4_10030_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30000225SMESG000011434.1 dd_Smed_v4_10030_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30000225SMESG000011434.1 dd_Smed_v4_10030_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30000225SMESG000058328.1 Contig4057GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30000225SMESG000011434.1 Contig4057GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Human
Match: WBP4 (WW domain binding protein 4 [Source:HGNC Symbol;Acc:HGNC:12739])

HSP 1 Score: 92.4337 bits (228), Expect = 4.038e-21
Identity = 64/179 (35.75%), Postives = 86/179 (48.04%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMEL-----LNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNV-------QQ-----------DQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGF 520
            MAD WKSQPKK+C+ CKCW+ADN+ S EFHE G  HK  V ++ISE+  K  +K K E+  KA+ E          AYQ  LK +                     ++ E+L+ PS   + S +       QQ           D  K +W    T EG  YY+++ +  S WEKP GF
Sbjct:    1 MADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEE--KASKEFAAMEAAALKAYQEDLKRLG--------------------LESEILE-PSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGASQWEKPEGF 156
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Celegans
Match: F56G4.4 (pep chromosome:WBcel235:I:11374620:11380127:1 gene:WBGene00010159.1 transcript:F56G4.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F56G4.4)

HSP 1 Score: 58.5362 bits (140), Expect = 1.037e-9
Identity = 56/225 (24.89%), Postives = 90/225 (40.00%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMEL-----------------------LNAAAYQGMLKDIAKDPKKVSVYGVEMNDK-----------------------TRNDIKKEL--LKMPSA-------QLIQSNVQQDQKKC---QWKSARTKEGLI--YYWNVHTKQSTWEKPSGFVDEEQKDKK 547
            MA+ W S  K++C++CK W  +N+ S++ H+ G RHKA +Q++I E   K  ++  A  DMK N  L                       L A   +  + D +K  K V     EM+ +                       T++D+      L  P+A        L    + + Q +C   QW  A+        YYWN+    + W  P+ F  E+Q ++K
Sbjct:    1 MAEQWVSTGKRFCDICKVWFGNNRASQDHHDRGERHKAMLQQRIRETMQKGKKQELA--DMKLNGTLAKMEAAAAASMARNGEAIVAGPSLPATGLRMNIFDPSKH-KDVGSMAKEMSSRREAAGNVKRGAQSAAVGAPNVKITKDDVVSAYRDLTNPNAAGPALPEHLAVGYMPETQVQCVEIQWVRAKNPSAPPGHYYWNLFDNSTRWTAPAHFYTEQQYEQK 222
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Fly
Match: CG4291 (gene:FBgn0031287 transcript:FBtr0334797)

HSP 1 Score: 77.7962 bits (190), Expect = 2.597e-16
Identity = 53/218 (24.31%), Postives = 99/218 (45.41%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDIAK--DPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQ-------SNVQQDQKKCQ---------------WKSARTKEGLIYYWNVHTKQSTWEKP-SGFVDEEQKDKKIKRTSTLEEVVPVKKSRIVFNNNIKRDI 631
            M + WKS  +K+C+ CKCWL+DNK S  FHE G RHK  V ++I+++     +  +  + M A +  +  AA +   +D+    D    S+  V     T             ++ +        S+ ++DQ++                 W   ++ EG  YYWNV T +S W+ P  G++  E+ + +I + +  ++ +   +  + F  N+  ++
Sbjct:    1 MTEYWKSNERKFCDFCKCWLSDNKASVAFHESGKRHKMNVAKRITDISRNSEKSERERQKMDAEIRKMEEAAMKSYAQDVHSRGDMTARSINTVMRATATAAASGGAHSFAGRSRQVDPMRLEGLSDEEEDQRRVAPGKVTSDAAVPEASLWVEGKSDEGHTYYWNVKTNESVWKPPKEGYLSYEEYE-RINQLAIDQQQISQAEESLKFRANVDEEV 217
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Fly
Match: CG4291 (gene:FBgn0031287 transcript:FBtr0078034)

HSP 1 Score: 77.7962 bits (190), Expect = 2.597e-16
Identity = 53/218 (24.31%), Postives = 99/218 (45.41%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDIAK--DPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQ-------SNVQQDQKKCQ---------------WKSARTKEGLIYYWNVHTKQSTWEKP-SGFVDEEQKDKKIKRTSTLEEVVPVKKSRIVFNNNIKRDI 631
            M + WKS  +K+C+ CKCWL+DNK S  FHE G RHK  V ++I+++     +  +  + M A +  +  AA +   +D+    D    S+  V     T             ++ +        S+ ++DQ++                 W   ++ EG  YYWNV T +S W+ P  G++  E+ + +I + +  ++ +   +  + F  N+  ++
Sbjct:    1 MTEYWKSNERKFCDFCKCWLSDNKASVAFHESGKRHKMNVAKRITDISRNSEKSERERQKMDAEIRKMEEAAMKSYAQDVHSRGDMTARSINTVMRATATAAASGGAHSFAGRSRQVDPMRLEGLSDEEEDQRRVAPGKVTSDAAVPEASLWVEGKSDEGHTYYWNVKTNESVWKPPKEGYLSYEEYE-RINQLAIDQQQISQAEESLKFRANVDEEV 217
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Zebrafish
Match: wbp4 (WW domain binding protein 4 [Source:ZFIN;Acc:ZDB-GENE-050522-342])

HSP 1 Score: 63.929 bits (154), Expect = 1.488e-12
Identity = 39/85 (45.88%), Postives = 48/85 (56.47%), Query Frame = 2 
Query:   56 ADVWKSQPKKYCEVCKCW--LADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMK---ANMELLNAAAYQGMLKDIA 295
            AD WKSQP+K+C+ CKCW  ++ +  S EFHE G  HK  V  KI E+  K   K K EK M    A ME     AY+  LK +A
Sbjct:    1 ADYWKSQPRKFCQYCKCWFVISVSPQSVEFHERGKNHKENVAAKIQEIRKKSVAKAKQEKKMSKDFAAMEDAAQKAYEEDLKRLA 85
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Zebrafish
Match: wbp4 (WW domain binding protein 4 [Source:ZFIN;Acc:ZDB-GENE-050522-342])

HSP 1 Score: 62.003 bits (149), Expect = 6.376e-12
Identity = 40/83 (48.19%), Postives = 46/83 (55.42%), Query Frame = 2 
Query:   56 ADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMK---ANMELLNAAAYQGMLKDIA 295
            AD WKSQP+K+C+ CK    DNK S EFHE G  HK  V  KI E+  K   K K EK M    A ME     AY+  LK +A
Sbjct:    1 ADYWKSQPRKFCQYCK---XDNKPSVEFHERGKNHKENVAAKIQEIRKKSVAKAKQEKKMSKDFAAMEDAAQKAYEEDLKRLA 80
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Zebrafish
Match: wbp4 (WW domain binding protein 4 [Source:ZFIN;Acc:ZDB-GENE-050522-342])

HSP 1 Score: 50.0618 bits (118), Expect = 1.429e-7
Identity = 35/83 (42.17%), Postives = 44/83 (53.01%), Query Frame = 2 
Query:   56 ADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMK---ANMELLNAAAYQGMLKDIA 295
            AD WKSQP+K+C+     ++ +  S EFHE G  HK  V  KI E+  K   K K EK M    A ME     AY+  LK +A
Sbjct:    1 ADYWKSQPRKFCQYL-LVISVSPQSVEFHERGKNHKENVAAKIQEIRKKSVAKAKQEKKMSKDFAAMEDAAQKAYEEDLKRLA 82
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Xenopus
Match: wbp4 (WW domain binding protein 4 [Source:NCBI gene;Acc:734007])

HSP 1 Score: 94.7449 bits (234), Expect = 5.964e-22
Identity = 73/175 (41.71%), Postives = 93/175 (53.14%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKA-EKDMK--ANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIK-KELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTST 565
            MAD WKSQPKK+C  CKCW+ADNK S EFHE G  HK  V +KISE+  K  +K K  EK  K  A ME     AY+  LK +  D   V V       K RN+ K KE+            +++   K QWK   + EG  YY+N  T +S WE+P GF ++ +K  K   +S 
Sbjct:    1 MADYWKSQPKKFCTYCKCWIADNKPSIEFHERGKNHKENVTKKISEIKKKSMDKAKEDEKKSKEFAAMEEAALKAYEEDLKRLQGD-VPVPVGPTVQQIKARNENKWKEI----------EAIERVHAKKQWKKEISPEGYPYYYNTLTGESRWEEPEGFQEKSEKTDKAGSSSA 164
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Xenopus
Match: wbp4 (WW domain binding protein 4 [Source:NCBI gene;Acc:734007])

HSP 1 Score: 94.7449 bits (234), Expect = 5.964e-22
Identity = 73/175 (41.71%), Postives = 93/175 (53.14%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKA-EKDMK--ANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIK-KELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTST 565
            MAD WKSQPKK+C  CKCW+ADNK S EFHE G  HK  V +KISE+  K  +K K  EK  K  A ME     AY+  LK +  D   V V       K RN+ K KE+            +++   K QWK   + EG  YY+N  T +S WE+P GF ++ +K  K   +S 
Sbjct:    1 MADYWKSQPKKFCTYCKCWIADNKPSIEFHERGKNHKENVTKKISEIKKKSMDKAKEDEKKSKEFAAMEEAALKAYEEDLKRLQGD-VPVPVGPTVQQIKARNENKWKEI----------EAIERVHAKKQWKKEISPEGYPYYYNTLTGESRWEEPEGFQEKSEKTDKAGSSSA 164
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Xenopus
Match: wbp4 (WW domain binding protein 4 [Source:NCBI gene;Acc:734007])

HSP 1 Score: 92.0485 bits (227), Expect = 4.615e-21
Identity = 72/174 (41.38%), Postives = 92/174 (52.87%), Query Frame = 2 
Query:   56 ADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKA-EKDMK--ANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIK-KELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTST 565
            AD WKSQPKK+C  CKCW+ADNK S EFHE G  HK  V +KISE+  K  +K K  EK  K  A ME     AY+  LK +  D   V V       K RN+ K KE+            +++   K QWK   + EG  YY+N  T +S WE+P GF ++ +K  K   +S 
Sbjct:    2 ADYWKSQPKKFCTYCKCWIADNKPSIEFHERGKNHKENVTKKISEIKKKSMDKAKEDEKKSKEFAAMEEAALKAYEEDLKRLQGD-VPVPVGPTVQQIKARNENKWKEI----------EAIERVHAKKQWKKEISPEGYPYYYNTLTGESRWEEPEGFQEKSEKTDKAGSSSA 164
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Mouse
Match: Wbp4 (WW domain binding protein 4 [Source:MGI Symbol;Acc:MGI:109568])

HSP 1 Score: 92.0485 bits (227), Expect = 1.789e-21
Identity = 61/166 (36.75%), Postives = 86/166 (51.81%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMEL-----LNAAAYQGMLKDIAKD-PKKVSVYGVEMNDKTRNDIKKELLKMPSAQ----LIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGF 520
            MAD WKSQPKK+C+ CKCW+ADN+ S EFHE G  HK  V R+ISE+  K  +K K E+  KA+ E          AYQ  LK +    P  +S       + T + +   +   P++       +   +++  K  W    T +G  YY+++ T  S WEKP GF
Sbjct:    1 MADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVARRISEIKQKSLDKAKEEE--KASKEFAAMEAAALKAYQEDLKRLGLPLPSDIS-------EPTVSPVISTVQPTPTSNQQKEKKKKKKKKEASKGGWVEGVTADGHCYYYDLITGASQWEKPEGF 157
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Mouse
Match: Wbp4 (WW domain binding protein 4 [Source:MGI Symbol;Acc:MGI:109568])

HSP 1 Score: 92.8189 bits (229), Expect = 1.996e-21
Identity = 61/166 (36.75%), Postives = 86/166 (51.81%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMEL-----LNAAAYQGMLKDIAKD-PKKVSVYGVEMNDKTRNDIKKELLKMPSAQ----LIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGF 520
            MAD WKSQPKK+C+ CKCW+ADN+ S EFHE G  HK  V R+ISE+  K  +K K E+  KA+ E          AYQ  LK +    P  +S       + T + +   +   P++       +   +++  K  W    T +G  YY+++ T  S WEKP GF
Sbjct:    1 MADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVARRISEIKQKSLDKAKEEE--KASKEFAAMEAAALKAYQEDLKRLGLPLPSDIS-------EPTVSPVISTVQPTPTSNQQKEKKKKKKKKEASKGGWVEGVTADGHCYYYDLITGASQWEKPEGF 157
[Close]
BLAST of WW domain-binding protein 4 vs. UniProt/SwissProt
Match: sp|Q5HZF2|WBP4_RAT (WW domain-binding protein 4 OS=Rattus norvegicus OX=10116 GN=Wbp4 PE=2 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 8.686e-22
Identity = 61/165 (36.97%), Postives = 87/165 (52.73%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMEL-----LNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQ----LIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGF 520
            MAD WKSQPKK+C+ CKCW+ADN+ S EFHE G  HK  V RKISE+  K  +K K E+  KA+ E          AYQ  LK +            ++++ T + +   +   P+A       +   +++  K +W    T +G  YY+++ T  S WEKP GF
Sbjct:    1 MADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVARKISEIKQKSLDKAKEEE--KASKEFAAMEAAALKAYQEDLKRLG--------LQSDISEPTISPVTNTVQPTPTANQQKEKKKKKKKKEASKGRWVEGVTADGHCYYYDLVTGASQWEKPEGF 155
[Close]
BLAST of WW domain-binding protein 4 vs. UniProt/SwissProt
Match: sp|Q5F457|WBP4_CHICK (WW domain-binding protein 4 OS=Gallus gallus OX=9031 GN=WBP4 PE=2 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 3.740e-21
Identity = 64/184 (34.78%), Postives = 90/184 (48.91%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANM---ELLNAAAYQGMLKDIAKDPKKVS-------VYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQK--KCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTSTL 568
            MAD WKSQPKK+C+ CKCW+ADN+ S +FHE G  HK  V ++ISE+  K  EK K E++M       E     AYQ  LK +   P  V           +    K + + K++  K    +  +    +  K    +W    + EG  YY+N  T +S WEKP GF    Q + K   T ++
Sbjct:    1 MADYWKSQPKKFCDYCKCWIADNRPSIDFHERGKNHKENVAKRISEIRKKSMEKAKEEENMSKEFAAMEEAAMKAYQEDLKRLGIKPDDVGPSSTLNKTQSITAEGKEKKEKKEKKEKKEKKKKTREGTSESPKTEPKEWVQGLSPEGYTYYYNTKTGESQWEKPKGF----QGNSKTSHTGSV 180
[Close]
BLAST of WW domain-binding protein 4 vs. UniProt/SwissProt
Match: sp|Q61048|WBP4_MOUSE (WW domain-binding protein 4 OS=Mus musculus OX=10090 GN=Wbp4 PE=1 SV=4)

HSP 1 Score: 92.8189 bits (229), Expect = 1.396e-20
Identity = 61/166 (36.75%), Postives = 86/166 (51.81%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMEL-----LNAAAYQGMLKDIAKD-PKKVSVYGVEMNDKTRNDIKKELLKMPSAQ----LIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGF 520
            MAD WKSQPKK+C+ CKCW+ADN+ S EFHE G  HK  V R+ISE+  K  +K K E+  KA+ E          AYQ  LK +    P  +S       + T + +   +   P++       +   +++  K  W    T +G  YY+++ T  S WEKP GF
Sbjct:    1 MADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVARRISEIKQKSLDKAKEEE--KASKEFAAMEAAALKAYQEDLKRLGLPLPSDIS-------EPTVSPVISTVQPTPTSNQQKEKKKKKKKKEASKGGWVEGVTADGHCYYYDLITGASQWEKPEGF 157
[Close]
BLAST of WW domain-binding protein 4 vs. UniProt/SwissProt
Match: sp|O75554|WBP4_HUMAN (WW domain-binding protein 4 OS=Homo sapiens OX=9606 GN=WBP4 PE=1 SV=1)

HSP 1 Score: 92.4337 bits (228), Expect = 1.939e-20
Identity = 64/179 (35.75%), Postives = 86/179 (48.04%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMEL-----LNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNV-------QQ-----------DQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGF 520
            MAD WKSQPKK+C+ CKCW+ADN+ S EFHE G  HK  V ++ISE+  K  +K K E+  KA+ E          AYQ  LK +                     ++ E+L+ PS   + S +       QQ           D  K +W    T EG  YY+++ +  S WEKP GF
Sbjct:    1 MADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEE--KASKEFAAMEAAALKAYQEDLKRLG--------------------LESEILE-PSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGASQWEKPEGF 156
[Close]
BLAST of WW domain-binding protein 4 vs. UniProt/SwissProt
Match: sp|Q7XA66|ZOP1_ARATH (Zinc finger protein ZOP1 OS=Arabidopsis thaliana OX=3702 GN=ZOP1 PE=1 SV=1)

HSP 1 Score: 52.373 bits (124), Expect = 8.257e-7
Identity = 30/84 (35.71%), Postives = 47/84 (55.95%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLN---AAAYQGMLKDIA 295
            M + W SQ  K+CE CK W+ +N  S   H+ G RH+  V +K++++  +   K   +K++K N +LL    A A +   KDIA
Sbjct:    1 MTEYWVSQGNKWCEFCKIWIQNNPTSIRNHDLGKRHRECVDKKLTDMRERSAAK---DKELKKNEKLLQQIEAKATRSYQKDIA 81
[Close]
BLAST of WW domain-binding protein 4 vs. TrEMBL
Match: A0A4S2LTU6 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005130 PE=4 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 3.154e-35
Identity = 64/166 (38.55%), Postives = 103/166 (62.05%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQKKC------QWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEE 532
            MAD WKS PKK+C+VCKCW+ADNK+S + HE G RHKA V++K++EL        + E+ ++A+++ +N  A+ GM+KD+A+DP     YG+ + D+ + D++ ++ ++ S    +  V +   K       +W+ A T +G  YYWN  T+ + WE+P G V  E
Sbjct:    1 MADYWKSNPKKFCDVCKCWMADNKISVQNHETGLRHKANVEKKMNELLRNNKNSEREEQKLRASIQQMNDNAFVGMMKDLARDPSLAKRYGITLTDQAQQDVRDKVSEITSKDKTKKPVSKPVPKAPKTATPEWREATTPDGRKYYWNTVTRVTQWERPEGDVAPE 166
[Close]
BLAST of WW domain-binding protein 4 vs. TrEMBL
Match: A0A5J4NR42 (WW domain-binding protein 4 OS=Paragonimus westermani OX=34504 GN=DEA37_0000394 PE=4 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 4.366e-35
Identity = 62/165 (37.58%), Postives = 101/165 (61.21%), Query Frame = 2 
Query:   50 KMADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKM---PSAQLIQS-NVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEE 532
            +MAD WKS P+KYCEVCKCW+ADNK+S + HE G RHKA V +K++EL        + E++++ N++ +N AA+ GM+KD+A+DP     YGV + +  + ++ +++  +   P ++             C+W  A   +G  YYWN  T+ + WE+P+G + +E
Sbjct:    7 QMADYWKSNPRKYCEVCKCWMADNKISIQNHESGMRHKANVDKKMNELQRNNKNAERDEQNLRNNLQQINDAAFVGMMKDLARDPALAKRYGVVLTEHAQEEVIEKVAALNGKPKSEPTPGKKAATKTSVCEWHEATAADGRKYYWNAITRATQWERPAGLIAQE 171
[Close]
BLAST of WW domain-binding protein 4 vs. TrEMBL
Match: A0A0X3QDW1 (WW domain-binding protein 4 OS=Schistocephalus solidus OX=70667 GN=WBP4 PE=4 SV=1)

HSP 1 Score: 134.035 bits (336), Expect = 1.700e-34
Identity = 70/177 (39.55%), Postives = 103/177 (58.19%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKM--------PSAQLIQSNVQQD-QKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKR 556
            MAD WKS PKK+C++CKCWLADNK+S   HE G RHKA VQ+K+S+L  ++N K   E  M+  + L+N  A+ GM+KDI +DP     YGV + D+   ++KK++ ++        P A    +  +   Q   +WK  +T +G IYYWN  T  + WEKP   ++       ++R
Sbjct:    1 MADYWKSNPKKFCDICKCWLADNKISITNHETGMRHKANVQKKLSDL--RKNCKESTEGKMREKISLINDMAFVGMMKDIERDPSLAKRYGVSLTDEKFANMKKKIDELEKSGVSSKPKAPPTSTAPRPPTQTVYEWKEVKTADGSIYYWNKKTGVTQWEKPQASIEPVDDSASVQR 175
[Close]
BLAST of WW domain-binding protein 4 vs. TrEMBL
Match: A0A074ZLG7 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_14467 PE=4 SV=1)

HSP 1 Score: 136.346 bits (342), Expect = 2.142e-34
Identity = 63/166 (37.95%), Postives = 101/166 (60.84%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQKKC------QWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEE 532
            MAD WKS PKK+C+VCKCW+ADNK+S + HE G RHKA V++K++EL        + E+ ++ +++ +N  A+ GM+KD+A+DP     YG+ + D+ + D++ ++ ++ S    +  V     K       +W+ A T +G  YYWN  T+ + WE+P G V  E
Sbjct:    1 MADYWKSNPKKFCDVCKCWMADNKISVQNHESGLRHKANVEKKMNELLRNNKNSEREEQKLRDSIQQMNDNAFVGMMKDLARDPSLAKRYGITLTDQAQQDVRDKVSEITSKDKTKKPVSTPAPKTPKTATPEWREATTPDGRKYYWNTVTRVTQWERPEGDVAPE 166
[Close]
BLAST of WW domain-binding protein 4 vs. TrEMBL
Match: A0A0X3P7E6 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR150506 PE=4 SV=1)

HSP 1 Score: 134.806 bits (338), Expect = 2.021e-33
Identity = 70/177 (39.55%), Postives = 103/177 (58.19%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKM--------PSAQLIQSNVQQD-QKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKR 556
            MAD WKS PKK+C++CKCWLADNK+S   HE G RHKA VQ+K+S+L  ++N K   E  M+  + L+N  A+ GM+KDI +DP     YGV + D+   ++KK++ ++        P A    +  +   Q   +WK  +T +G IYYWN  T  + WEKP   ++       ++R
Sbjct:    1 MADYWKSNPKKFCDICKCWLADNKISITNHETGMRHKANVQKKLSDL--RKNCKESTEGKMREKISLINDMAFVGMMKDIERDPSLAKRYGVSLTDEKFANMKKKIDELEKSGVSSKPKAPPTSTAPRPPTQTVYEWKEVKTADGSIYYWNKKTGVTQWEKPQASIEPVDDSASVQR 175
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Cavefish
Match: ENSAMXT00000013752.2 (pep primary_assembly:Astyanax_mexicanus-2.0:13:8782034:8786381:1 gene:ENSAMXG00000013362.2 transcript:ENSAMXT00000013752.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.7886 bits (177), Expect = 7.825e-16
Identity = 37/79 (46.84%), Postives = 48/79 (60.76%), Query Frame = 2 
Query:   56 ADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDI 292
            AD WKSQP+K+C+ CKCW+ADNK S EFHE G  HK  V  KI E+  K  +K K E+ M      +  AA +   +D+
Sbjct:    1 ADYWKSQPRKFCQYCKCWIADNKPSIEFHERGKNHKQNVTAKIDEIKKKSIDKAKKEEKMSKEFAAMEEAALKAYEEDM 79
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Nematostella
Match: EDO40481 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S772])

HSP 1 Score: 84.7297 bits (208), Expect = 2.623e-19
Identity = 58/187 (31.02%), Postives = 91/187 (48.66%), Query Frame = 2 
Query:   56 ADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDIA------KDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQ-----------------LIQSNVQQDQKKC--QWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKD 541
            A+ W+SQPKK+C+ CKCW+ DNK S EFHE G +H+  VQ KI+ +  K  + +K +++ + +M  + AAA     KD+       + P K      +   + + DI+  + + P++Q                  I  N  Q    C   W  +++ EG  YY+N  T+ S WE P+    EE  D
Sbjct:   20 AEYWRSQPKKFCDFCKCWITDNKPSVEFHERGKKHQENVQLKITAVRKKGIQSLKKDQEFQHDMAAIEAAALAAYKKDLGIEDTEEEKPSKAKP-DHQSEKRPQFDIRGAVNREPASQDPPACHDPPASSSSPSCSIVYNGSQPVVHCTHSWAVSQSPEGYYYYYNSQTQASQWEVPNCLQPEESND 205
[Close]
BLAST of WW domain-binding protein 4 vs. Ensembl Medaka
Match: ENSORLT00000004049.2 (WW domain binding protein 4 [Source:NCBI gene;Acc:101161956])

HSP 1 Score: 97.4413 bits (241), Expect = 4.600e-23
Identity = 58/168 (34.52%), Postives = 84/168 (50.00%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQKKCQ--------------WKSARTKEGLIYYWNVHTKQSTWEKPS 514
            MAD WKSQP+K+C+ CKCW+ADNK S EFHE G  HK  V  KISE+  K  +K K E+ M      +  AA +   +D+ +  ++   +   +   T    + + L MP     Q   ++ QKK +              W     + G +YY+N  T +S WEKP+
Sbjct:    1 MADYWKSQPRKFCQYCKCWIADNKPSIEFHERGKNHKENVAAKISEIKKKSIQKAKQEERMSKQFAAMEEAAVKAYEEDLKRMERESQGFSYPVKAPTS---QPQPLVMPPKAAPQHQPRKQQKKKEKMSRKPREQPTARVWVEGFAENGHMYYYNTITGESQWEKPA 165
[Close]
BLAST of WW domain-binding protein 4 vs. Planmine SMEST
Match: SMESG000011434.1 (SMESG000011434.1)

HSP 1 Score: 419.083 bits (1076), Expect = 7.410e-151
Identity = 204/204 (100.00%), Postives = 204/204 (100.00%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTSTLEEVVPVKKSRIVFNNNIKRDIKPDLSPIDKSK 664
            MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTSTLEEVVPVKKSRIVFNNNIKRDIKPDLSPIDKSK
Sbjct:    1 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTSTLEEVVPVKKSRIVFNNNIKRDIKPDLSPIDKSK 204
[Close]
BLAST of WW domain-binding protein 4 vs. Planmine SMEST
Match: SMESG000011434.1 (SMESG000011434.1)

HSP 1 Score: 409.838 bits (1052), Expect = 5.050e-147
Identity = 204/218 (93.58%), Postives = 204/218 (93.58%), Query Frame = 2 
Query:   53 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNA--------------AAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTSTLEEVVPVKKSRIVFNNNIKRDIKPDLSPIDKSK 664
            MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNA              AAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTSTLEEVVPVKKSRIVFNNNIKRDIKPDLSPIDKSK
Sbjct:    1 MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFKENEKMKAEKDMKANMELLNAVRISLTDHFNVFMKAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTSTLEEVVPVKKSRIVFNNNIKRDIKPDLSPIDKSK 218
[Close]
BLAST of WW domain-binding protein 4 vs. Planmine SMEST
Match: SMESG000011434.1 (SMESG000011434.1)

HSP 1 Score: 305.449 bits (781), Expect = 8.639e-107
Identity = 150/150 (100.00%), Postives = 150/150 (100.00%), Query Frame = 2 
Query:  215 MKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTSTLEEVVPVKKSRIVFNNNIKRDIKPDLSPIDKSK 664
            MKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTSTLEEVVPVKKSRIVFNNNIKRDIKPDLSPIDKSK
Sbjct:    1 MKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRNDIKKELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTWEKPSGFVDEEQKDKKIKRTSTLEEVVPVKKSRIVFNNNIKRDIKPDLSPIDKSK 150
The following BLAST results are available for this feature:
BLAST of WW domain-binding protein 4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
WBP44.038e-2135.75WW domain binding protein 4 [Source:HGNC Symbol;Ac... [more]
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BLAST of WW domain-binding protein 4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
F56G4.41.037e-924.89pep chromosome:WBcel235:I:11374620:11380127:1 gene... [more]
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BLAST of WW domain-binding protein 4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG42912.597e-1624.31gene:FBgn0031287 transcript:FBtr0334797[more]
CG42912.597e-1624.31gene:FBgn0031287 transcript:FBtr0078034[more]
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BLAST of WW domain-binding protein 4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
wbp41.488e-1245.88WW domain binding protein 4 [Source:ZFIN;Acc:ZDB-G... [more]
wbp46.376e-1248.19WW domain binding protein 4 [Source:ZFIN;Acc:ZDB-G... [more]
wbp41.429e-742.17WW domain binding protein 4 [Source:ZFIN;Acc:ZDB-G... [more]
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BLAST of WW domain-binding protein 4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
wbp45.964e-2241.71WW domain binding protein 4 [Source:NCBI gene;Acc:... [more]
wbp45.964e-2241.71WW domain binding protein 4 [Source:NCBI gene;Acc:... [more]
wbp44.615e-2141.38WW domain binding protein 4 [Source:NCBI gene;Acc:... [more]
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BLAST of WW domain-binding protein 4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Wbp41.789e-2136.75WW domain binding protein 4 [Source:MGI Symbol;Acc... [more]
Wbp41.996e-2136.75WW domain binding protein 4 [Source:MGI Symbol;Acc... [more]
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BLAST of WW domain-binding protein 4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5HZF2|WBP4_RAT8.686e-2236.97WW domain-binding protein 4 OS=Rattus norvegicus O... [more]
sp|Q5F457|WBP4_CHICK3.740e-2134.78WW domain-binding protein 4 OS=Gallus gallus OX=90... [more]
sp|Q61048|WBP4_MOUSE1.396e-2036.75WW domain-binding protein 4 OS=Mus musculus OX=100... [more]
sp|O75554|WBP4_HUMAN1.939e-2035.75WW domain-binding protein 4 OS=Homo sapiens OX=960... [more]
sp|Q7XA66|ZOP1_ARATH8.257e-735.71Zinc finger protein ZOP1 OS=Arabidopsis thaliana O... [more]
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BLAST of WW domain-binding protein 4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2LTU63.154e-3538.55Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A5J4NR424.366e-3537.58WW domain-binding protein 4 OS=Paragonimus westerm... [more]
A0A0X3QDW11.700e-3439.55WW domain-binding protein 4 OS=Schistocephalus sol... [more]
A0A074ZLG72.142e-3437.95Uncharacterized protein OS=Opisthorchis viverrini ... [more]
A0A0X3P7E62.021e-3339.55Uncharacterized protein OS=Schistocephalus solidus... [more]
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BLAST of WW domain-binding protein 4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSAMXT00000013752.27.825e-1646.84pep primary_assembly:Astyanax_mexicanus-2.0:13:878... [more]
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BLAST of WW domain-binding protein 4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of WW domain-binding protein 4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of WW domain-binding protein 4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO404812.623e-1931.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of WW domain-binding protein 4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSORLT00000004049.24.600e-2334.52WW domain binding protein 4 [Source:NCBI gene;Acc:... [more]
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BLAST of WW domain-binding protein 4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000011434.17.410e-151100.00SMESG000011434.1[more]
SMESG000011434.15.050e-14793.58SMESG000011434.1[more]
SMESG000011434.18.639e-107100.00SMESG000011434.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30000225 ID=SMED30000225|Name=WW domain-binding protein 4|organism=Schmidtea mediterranea sexual|type=transcript|length=760bp
TGTGTATTGATTTTTCATAAATATAACATAATATTATTTTACTATTAACA
AAATGGCAGATGTATGGAAAAGTCAACCTAAAAAATATTGTGAAGTTTGT
AAATGTTGGTTAGCTGATAATAAAGTGAGTAGAGAATTCCATGAAGAAGG
TACTAGACATAAAGCAGCTGTTCAAAGAAAAATCAGTGAATTACATTTTA
AGGAAAATGAGAAGATGAAAGCTGAAAAAGATATGAAAGCTAATATGGAA
TTATTAAATGCTGCAGCTTATCAAGGTATGCTTAAAGATATTGCAAAAGA
TCCGAAAAAAGTTTCCGTTTATGGTGTTGAAATGAATGATAAGACCAGGA
ATGATATCAAAAAGGAATTACTTAAAATGCCATCAGCTCAATTAATACAA
TCTAATGTACAACAAGATCAGAAAAAGTGTCAATGGAAGTCAGCCAGAAC
GAAAGAAGGTCTTATCTACTATTGGAATGTTCATACGAAACAATCTACTT
GGGAAAAGCCATCAGGTTTTGTCGATGAAGAACAAAAGGATAAAAAAATT
AAGCGTACTTCTACACTAGAAGAAGTTGTTCCAGTTAAAAAATCTCGCAT
TGTTTTCAACAACAATATAAAACGCGATATAAAACCAGATTTGTCTCCAA
TCGATAAATCGAAATAATTAGATTTAGTAATAAATGTACAGGTTTTCTTT
TATAACAGTGTCACATTTGTTTAATAAACAATTGCTTTTTAAATATTTTT
TATCGTGTCA
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protein sequence of SMED30000225-orf-1

>SMED30000225-orf-1 ID=SMED30000225-orf-1|Name=SMED30000225-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=205bp
MADVWKSQPKKYCEVCKCWLADNKVSREFHEEGTRHKAAVQRKISELHFK
ENEKMKAEKDMKANMELLNAAAYQGMLKDIAKDPKKVSVYGVEMNDKTRN
DIKKELLKMPSAQLIQSNVQQDQKKCQWKSARTKEGLIYYWNVHTKQSTW
EKPSGFVDEEQKDKKIKRTSTLEEVVPVKKSRIVFNNNIKRDIKPDLSPI
DKSK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0000398mRNA splicing, via spliceosome
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0002032epidermal cell
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR040023WBP4
IPR036236Znf_C2H2_sf
IPR036020WW_dom_sf
IPR003604Matrin/U1-like-C_Znf_C2H2
IPR001202WW_dom
IPR013085U1-CZ_Znf_C2H2
IPR000690Matrin/U1-C_Znf_C2H2
Vocabulary: molecular function
TermDefinition
GO:0008270zinc ion binding
GO:0003676nucleic acid binding
GO:0005515protein binding
GO:0046872metal ion binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 40..60
NoneNo IPR availableGENE3DG3DSA:3.30.160.60coord: 5..46
e-value: 8.9E-6
score: 27.1
NoneNo IPR availableGENE3DG3DSA:2.20.70.10coord: 121..166
e-value: 1.5E-12
score: 48.5
IPR001202WW domainSMARTSM00456ww_5coord: 123..155
e-value: 6.5E-7
score: 39.0
IPR001202WW domainPFAMPF00397WWcoord: 127..153
e-value: 2.8E-8
score: 33.7
IPR001202WW domainPROSITEPS01159WW_DOMAIN_1coord: 128..153
IPR001202WW domainPROSITEPS50020WW_DOMAIN_2coord: 128..155
score: 12.373
IPR001202WW domainCDDcd00201WWcoord: 128..153
e-value: 1.4967E-7
score: 44.0558
IPR003604Matrin/U1-C-like, C2H2-type zinc fingerSMARTSM00451ZnF_U1_5coord: 8..43
e-value: 7.0E-6
score: 35.5
IPR013085U1-C, C2H2-type zinc fingerPFAMPF06220zf-U1coord: 8..42
e-value: 3.0E-11
score: 42.9
IPR040023WW domain-binding protein 4PANTHERPTHR13173WW DOMAIN BINDING PROTEIN 4coord: 1..164
IPR000690Matrin/U1-C, C2H2-type zinc fingerPROSITEPS50171ZF_MATRINcoord: 11..42
score: 8.863
IPR036236Zinc finger C2H2 superfamilySUPERFAMILYSSF57667beta-beta-alpha zinc fingerscoord: 9..43
IPR036020WW domain superfamilySUPERFAMILYSSF51045WW domaincoord: 119..154