Otoferlin

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIA-----IKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNG-KPLTFEMSIGITGNLLDDYAKVAS---EKEPTPENQY-------------------VHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P + +  D+Q+S+T++EAR L G N++P+  V  G  K+ T +K  TN P+YNE+F FD  +S   M + IIKI  +   N      + +G ++G F +D  +VY+   H F  KWA L DP   +SG KGYVK D++V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT++++N+K A  GE K L D YV+V FAG  G+T V   +Y P WN+Q++FT+ FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RL++      + TS    +S   V V    P+S + AGK E + LFG   E ++I+    +NG KP+TFE++IG  GN +D  ++       KEP  E +                    V S    R   T D  YFH+PY  +KPC+++ +   D R R++  NI++ +  +L E +     +I  EK+   RR L+  +  L     + +S     +G + +T LD +  +    +LE M  + + L  ++KR  V +K+R C   ++ L     +PQ+ +PDIFI+M+  N RVAYAR+ +++++ S +  E G  C  + T++LK L       +  + +QA++++YLWLGL +  + +  GLP G+   +   G      PP  + Y  +  FQLR +++ AR++  +D SGLSDPFAR+        + +  +T  P WD+ L+ DN+        L+  PP +V+EI+D DS    +F+GR F +P V +  + Y   +    L+++ IYRG   AG++LAAF+L+++          G     D+  +   ++ +R   M      +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:  244 MEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKN-----LLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISSGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVP-PERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRNYT---LLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSNPELTSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDR---RNGDKPITFEVTIGNYGNEVDGLSRPQRPRPRKEPGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVT-DRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYPERR-LRGVLEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFSIVEEETGKDCAKVKTLFLK-LPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQI----------GPAGKADLPPINGPVDVDRGPIMP-----VPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSL 1226          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEI-VPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFN-----LFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            I+ + +YP ELE+  +F  F D   +F+L RGK  +D+D     +R  G FKG++C+Y +   +    +   +                                    T  +++ +   +P++ +VRVY+++A +LHP+D+NGK+DPYI ++LG  ++RD+ENYI K LNPVFGK  ++E +FP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   P+ IL  LC++  V  P +     RV + +R F   + IED++G +  + E +AL  L HW +I   G +LVPE++ETRPL  P+KPGI+QG LE+WVDM+P     P  P+DI+PRK   YELR  +  T++V L + +FFT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWR+++ FDYL AE+ IV ++K S++  DE EYK P  L +Q+ D+    +D  +G  +  L++FP+ AK  + C    +  A  + +     +F+ K+V+GWWPL+   ++++ +          VE E+ L+TAEEAE NPVGL R EP PLE P RPD SF+ FLNP  + +YF+ +  +W+L+K+ ++ + LL++ALF+Y+ PG +   I+
Sbjct: 1405 IDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDS-----------------------------------TYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGP-PGRVKVANRVFTGPSEIEDENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQC---TMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK------VEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1995          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIY-FGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEY 487
            M+L ++LK +      GD+  K+ FR     S  L+   ++  F + F WP+A  +D+N++L ++ +N ++V  +KL+G  ++    ++ E  + V + L+D+   I    +  E+ Y
Sbjct:    1 MALLIHLKTVSELRGRGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNEMLEIQVFNYSKVFSNKLIGTFRMVLQKVVEESHVEVTDTLIDDNNAIIKTSLCVEVRY 118          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIA-----IKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNG-KPLTFEMSIGITGNLLDDYAKVAS---EKEPTPENQY-------------------VHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P + +  D+Q+S+T++EAR L G N++P+  V  G  K+ T +K  TN P+YNE+F FD  +S   M + IIKI  +   N      + +G ++G F +D  +VY+   H F  KWA L DP   +SG KGYVK D++V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT++++N+K A  GE K L D YV+V FAG  G+T V   +Y P WN+Q++FT+ FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RL++      + TS    +S   V V    P+S + AGK E + LFG   E ++I+    +NG KP+TFE++IG  GN +D  ++       KEP  E +                    V S    R   T D  YFH+PY  +KPC+++ +   D R R++  NI++ +  +L E +     +I  EK+   RR L+  +  L     + +S     +G + +T LD +  +    +LE M  + + L  ++KR  V +K+R C   ++ L     +PQ+ +PDIFI+M+  N RVAYAR+ +++++ S +  E G  C  + T++LK L       +  + +QA++++YLWLGL +  + +  GLP G+   +   G      PP  + Y  +  FQLR +++ AR++  +D SGLSDPFAR+        + +  +T  P WD+ L+ DN+        L+  PP +V+EI+D DS    +F+GR F +P V +  + Y   +    L+++ IYRG   AG++LAAF+L+++          G     D+  +   ++ +R   M      +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:  244 MEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKN-----LLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISSGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVP-PERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRNYT---LLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSNPELTSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDR---RNGDKPITFEVTIGNYGNEVDGLSRPQRPRPRKEPGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVT-DRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYPERR-LRGVLEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFSIVEEETGKDCAKVKTLFLK-LPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQI----------GPAGKADLPPINGPVDVDRGPIMP-----VPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSL 1226          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEI-VPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFN-----LFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            I+ + +YP ELE+  +F  F D   +F+L RGK  +D+D     +R  G FKG++C+Y +   +    +   +                                    T  +++ +   +P++ +VRVY+++A +LHP+D+NGK+DPYI ++LG  ++RD+ENYI K LNPVFGK  ++E +FP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   P+ IL  LC++  V  P +     RV + +R F   + IED++G +  + E +AL  L HW +I   G +LVPE++ETRPL  P+KPGI+QG LE+WVDM+P     P  P+DI+PRK   YELR  +  T++V L + +FFT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWR+++ FDYL AE+ IV ++K S++  DE EYK P  L +Q+ D+    +D  +G  +  L++FP+ AK  + C    +  A  + +     +F+ K+V+GWWPL+   ++++ +          VE E+ L+TAEEAE NPVGL R EP PLE P RPD +F+ FLNP  +IKY I  R KW++IKI +  + LL++ LF+Y+ PG     +V K+ G
Sbjct: 1405 IDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDS-----------------------------------TYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGP-PGRVKVANRVFTGPSEIEDENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQC---TMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK------VEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKIVLALLGLLMLGLFLYSLPG----YMVKKLLG 1996          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIY-FGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEY 487
            M+L ++LK +      GD+  K+ FR     S  L+   ++  F + F WP+A  +D+N++L ++ +N ++V  +KL+G  ++    ++ E  + V + L+D+   I    +  E+ Y
Sbjct:    1 MALLIHLKTVSELRGRGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNEMLEIQVFNYSKVFSNKLIGTFRMVLQKVVEESHVEVTDTLIDDNNAIIKTSLCVEVRY 118          

Query:  710 KLPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPK-RPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTS---------------------------------YQPDSSKIGVDVRPCNPVSNT-------------VAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTP------------ENQYVHSMTQSRFAYTYDNK---------YFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRS-NVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVK--DIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQC 3727
            KL   I    ++ +++QI++TI EAR L G NI+P+  +  G +K+ + +K  TNSPFYNE+F FD    ++ + + IIKI       +V   ++    ++G F +D  +VY   GH F  KWA L DP    +G KGY+K DISV+  GD  K  P   D EE   IE NLLIP       R      V +Y+AE LP MN++I++N+  A  G+ K L D +VEVSFAG  GRT V      P W++Q+IF E FPP   R++I V D   + D  ++T FIDL+KI       ++GFLPT+GP+WINLYG+PR  +   L+   Q  N+   EGV++RGR+++ I                                     + D ++ G   +  N  ++T             V  K E +LLFG  +E T+I+  +G   KP++FE+SIG  GNL+D  +   S+K                +    H +     + T+  K         Y ++P++ KKPC++ I+   D   R+   N++EK+   L E I +   LI + +     + +KT + + I      +S  +       +T LD K   L   +LE M  + + +  + K+  +V E + E    V+ +   + +PQ+ +PD+FI+M+  N RVAYARI ++++++S +A + G  CG + T +LK       K    +++QA++ +YLWLG ++        LP GY  E  S       PP  + Y ++ +FQLR +++ AR +I +D +GLSDPFA++    H   + I +QT SP W++ L+ ++++ +     L  SPP VVVE++D D+    E+LG     P V +    Y   +L +  I+ G L+ G++LA F+L+++        ++GLP V+  DI ++                  +P  IRP LS +R E+L WGVR++++++++                 V++P+  I+  G  ++S  I  +   PNF       ++ LP +    PP++I   +   FG   +VG   I N +  + C
Sbjct:   68 KLLTKIHDGEVRSQNYQIAITITEARQLVGENIDPVVTIEIGDEKKQSTVKEGTNSPFYNEYFVFDFIGPQVHLFDKIIKI-------SVFHHKLIGSVLIGSFKVDLGTVYNQPGHQFCNKWALLTDPGDIRTGTKGYLKCDISVMGKGDVLKTSPKTSDTEEP--IEKNLLIPNGFP-LERPWARFYVRLYKAEGLPKMNSSIMANVTKAFVGDSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEMFPPLCRRVKIQVWDEGSMNDVALATHFIDLKKIS-NEQDGDKGFLPTFGPAWINLYGSPRNHS---LMDDYQEMNEGFGEGVSFRGRILVEIAVEILSGRAQESKFSKALKELKLPSKDKDSKSSKGKDKADKTEDGKSQQASNKTNSTEVEVESFDVPPEIVPEKNEEFLLFGAFFEATMIDRKIGD--KPISFEVSIGNFGNLIDGGSHHGSKKSAESAEEDLLPLLHEGQGDVAHDVPIPMASTTHPEKPLVTEGNRNYNYLPFEAKKPCVYFISSWGDQTFRLHWSNMLEKMADFLEESIEEVRELIKISQEAPEEK-MKTVLSDFISRSSAFISEAEKKPKMLNQTTLDKKRLTLCWQELEAMCKEAKGIIQQQKKKLSVDEMIHEAQNFVEKIRFLVDEPQHTIPDVFIWMLSNNRRVAYARIASKDLLYSPVAGQMGKHCGKIKTHFLKPPG----KRPAGWSVQAKVDVYLWLGSIKHASAILDNLPVGYEAEMSSKGAGTNHPPSNLLYQEQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVVELYDSDAVGKPEYLGATVAAPVVKLADQDYEPPRLCYHPIFCGNLSGGDLLAVFELLQVPPS----GLQGLPPVEPPDITQIYP----------------VPANIRPVLSKYRVEVLFWGVREMKKVQLLS----------------VDRPQALIECGGQGVKSCVIQSYKNNPNFSIQADAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTI-NYLKQFLC 1090          

Query: 4334 IMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMI-EDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCD--PFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            + +Y  +LE+  +F  F D  K+F L+RGK  EDD   +  DR  G FKG+ CIY                                          Q+   E    LR+ + +   +PV  ++RVYI+ A NL P+D +GKSDPYI++KLG  E++DR+ YIPK LNPVFG+  E++ TFP+ES L + IYD D +  DDLIGET IDLENR+ S H+  CG+   Y   GY  W+D   PT IL  LC+++ +  P +     ++ I ++ F  +T+  E+D    ++S E LAL+VLH W +I   G +LVPE+IETRPLY  +KPG++QG L+MWVDM+P     P  P+DI+PR+  GYELR T+  TE V L + N FT +K+ DI+VK W+K  + D Q+TDVHY SL+G+G FNWRF++ F YL AE  +V T++ +++ +++ E KTP  L +QV D   + SD  +G  +  L+ FP+ AK  ++CD   F+ +    K ++F+ K+VRGWWP   + +               VE E  LVTAEEAE NPVG  R EP PL  P RPD SF  F++P+  + Y I    K  +I  F++ + ++ + LFIY  PG+IS  IV
Sbjct: 1277 LQIYDGDLES--EFNNFEDWVKTFELFRGKSTEDDHGLDG-DRVIGKFKGSFCIYK---------------------------------------SPQDSSSEDSGQLRIQQGIPPNHPVTVLIRVYIVAAFNLSPADPDGKSDPYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSILIYDHDMIGTDDLIGETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFH--PGKIQIGNQVFSGKTIFTEEDTDETVESYEHLALKVLHSWEDIPEVGCRLVPEHIETRPLYHKDKPGMEQGRLQMWVDMFPKDMPQPGPPVDISPRRPKGYELRVTIWNTEDVILEDENIFTGQKSSDIYVKGWLKGLEDDKQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVITKRENIFSLEKMECKTPAVLVLQVWDFERLSSDDFLGTLEMNLNSFPRAAKSAKACDLAKFENASEETKISIFQQKRVRGWWPFSKSKELTGK-----------VEAEFHLVTAEEAEKNPVGKARKEPEPLAKPNRPDTSFSWFMSPFKCLYYLIWKNYKKYIIIAFILIILIIFLVLFIYTLPGAISRRIV 1854          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEI-VPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFN-----LFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            I+ + +YP ELE+  +F  F D   +F+L RGK  +D+D     +R  G FKG++C+Y +   +    +   +                                    T  +++ +   +P++ +VRVY+++A +LHP+D+NGK+DPYI ++LG  ++RD+ENYI K LNPVFGK  ++E +FP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   P+ IL  LC++  V  P +     RV + +R F   + IED++G +  + E +AL  L HW +I   G +LVPE++ETRPL  P+KPGI+QG LE+WVDM+P     P  P+DI+PRK   YELR  +  T++V L + +FFT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWR+++ FDYL AE+ IV ++K S++  DE EYK P  L +Q+ D+    +D  +G  +  L++FP+ AK  + C    +  A  + +     +F+ K+V+GWWPL+   ++++ +          VE E+ L+TAEEAE NPVGL R EP PLE P RPD +F+ FLNP  +IKY I  R KW++IKI +  + LL++ LF+Y+ PG     +V K+ G
Sbjct:  638 IDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDS-----------------------------------TYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGP-PGRVKVANRVFTGPSEIEDENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQC---TMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK------VEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKIVLALLGLLMLGLFLYSLPGY----MVKKLLG 1229          

Query: 2201 LISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            +I  EK+   RR L+  +  L     + +S     +G + +T LD +  +    +LE M  + + L  ++KR  V +K+R C   ++ L     +PQ+ +PDIFI+M+  N RVAYAR+ +++++ S +  E G  C  + T++LK L       +  + +QA++++YLWLGL +  + +  GLP G+   +   G      PP  + Y  +  FQLR +++ AR++  +D SGLSDPFAR+        + +  +T  P WD+ L+ DN+        L+  PP +V+EI+D DS    +F+GR F +P V +  + Y   +    L+++ IYRG   AG++LAAF+L+++          G     D+  +   ++ +R   M      +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:    1 MIKTEKSYPERR-LRGVLEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFSIVEEETGKDCAKVKTLFLK-LPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQI----------GPAGKADLPPINGPVDVDRGPIMP-----VPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSL 479          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEI-VPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFN-----LFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            I+ + +YP ELE+  +F  F D   +F+L RGK  +D+D     +R  G FKG++C+Y +   +    +   +                                    T  +++ +   +P++ +VRVY+++A +LHP+D+NGK+DPYI ++LG  ++RD+ENYI K LNPVFGK  ++E +FP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   P+ IL  LC++  V  P +     RV + +R F   + IED++G +  + E +AL  L HW +I   G +LVPE++ETRPL  P+KPGI+QG LE+WVDM+P     P  P+DI+PRK   YELR  +  T++V L + +FFT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWR+++ FDYL AE+ IV ++K S++  DE EYK P  L +Q+ D+    +D  +G  +  L++FP+ AK  + C    +  A  + +     +F+ K+V+GWWPL+   ++++ +          VE E+ L+TAEEAE NPVGL R EP PLE P RPD SF+ FLNP  + +YF+ +  +W+L+K+ ++ + LL++ALF+Y+ PG +   I+
Sbjct:  638 IDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDS-----------------------------------TYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGP-PGRVKVANRVFTGPSEIEDENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQC---TMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK------VEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1228          

Query: 2201 LISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            +I  EK+   RR L+  +  L     + +S     +G + +T LD +  +    +LE M  + + L  ++KR  V +K+R C   ++ L     +PQ+ +PDIFI+M+  N RVAYAR+ +++++ S +  E G  C  + T++LK L       +  + +QA++++YLWLGL +  + +  GLP G+   +   G      PP  + Y  +  FQLR +++ AR++  +D SGLSDPFAR+        + +  +T  P WD+ L+ DN+        L+  PP +V+EI+D DS    +F+GR F +P V +  + Y   +    L+++ IYRG   AG++LAAF+L+++          G     D+  +   ++ +R   M      +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:    1 MIKTEKSYPERR-LRGVLEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFSIVEEETGKDCAKVKTLFLK-LPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQI----------GPAGKADLPPINGPVDVDRGPIMP-----VPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSL 479          

Query: 5186 GSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAG-TAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKF------PQPAKFYRS---------------------CDPFQLSEACA-------------------------KFNLFRNKKVRGWWPLIYN----------PKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPW------NTIKYFIKY 6109
            GSQ++++    L  ++          LVPE++E+RPL+  +    Q+G L M+VD++P    AIPAP +I PRK I Y+LR  V+       +  +F   E   D++VK+++        KTD H++ L G G FNWRF+ NFDY   E  +V   K+ +     E      L +++ D      D ++G  +  L  F      P     Y +                     C  F     C                            N+F ++ + GWWP++             K  D   +D + I G VE++M L+T +EA+  P G  R+EP       +PD    S+ N W        IKYF  Y
Sbjct: 1635 GSQLQTIALFILRQMN----------LVPEHVESRPLFSDKGGRTQKGELRMFVDIFPMEYGAIPAPFNIAPRKPINYQLRIAVMDVRGAIPVKRSF--AEPVSDLYVKAFINGM-TKGHKTDTHFRVLDGTGEFNWRFLLNFDYNPWEKKVVAYTKNRFFCKPVEELVDPILVIELWDKNKFRKDRLLGDIELDLLDFIEGIGSPSDVGVYSTKKRQRGVKCPKCCTRRGCLCKCCIFCFETKCLCGKRKVKKKPFPKPVLFVEPEGYDDTVNIFESRNLYGWWPMLTEEYPHEEPQNAKKKNDDVGKDPKWIMGLVEMDMLLLTKQEADQEPAGKKRSEPNHSPFLEKPDRK--SWANSWLVSRIKPCIKYFWHY 1996          

Query: 4682 INPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLP-IYDKLTDR 5131
            + P   +VRVYII+A  L  +   G+ D Y+ +  G + V  ++NY  +  +P+FG+ +++ VT P E  L + +    R+  D  IG TTIDLENR L+  + + G+   +   G L+W+D   P  ILKS C +  + +P I  + T+R
Sbjct: 1378 VGPTRCLVRVYIIEANGLISNARKGRVDSYVKLHCGKQNVNLKKNYRSECCDPIFGERVDMTVTIPLEKDLKITVMGKRRILSDQEIGSTTIDLENRLLTKWRATGGLSGQFTVQGELQWRDQMTPMEILKSYCYKMMLSVPKIESRQTER 1528          

Query: 2828 FQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSI-YRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNF-EDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDY-------YQCDQVDNFREIDKTTIDE 3775
            +QLR Y+    +++    +  S  F RI  +++  ++ +   +++PIW+ET++  +++       +   PP V VE+    S+ +E  LG    +P V I G+       QW+ + +      G +LA F+L   +              KD+  +  +   N Y E  E    IP   RP    F  + L WGVR L                K+  +  V +P + + I         + D    PNF E  +VF ++ LP++ +  PP+ IN  ++  F  + +VG+C +++L  Y        + D  + + ++D    +E
Sbjct:  972 WQLRCYIMWGNDLLPVVKNS-SRAFVRISFAQYSKQTLLVDNSQNPIWNETVMFKSVLIAGGTRDIMKYPPVVSVEVVGECSNNEEANLGHFETKPNV-ICGNTDVRGTPQWFPLKFSNGRTRGAVLACFELYSEE-------------DKDLIPLEPKCKHN-YKERSE----IPTEFRPQFDKFHVQFLCWGVRNL----------------KKHKLLAVRRPFVGLTIGDQEFTLQPLKDVRRDPNFPEPMIVFGEVILPSALELSPPLIINLFDARAFNRQPLVGSCLVSDLHKYVSHIVPKVKSDHAERWEQLDLVITEE 1260          

Query:  944 IKIRGLSK-SNNVVAQRIFTGKVLGEFSIDAKSVYTNE-----GHSFFRKWA----PLIDPKSPTS---GEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDL--PCMNTNIISNIK--HAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPV--SNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDN-KYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEII--------RQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTA-KKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMA-DPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYK 2743
            IK + L K +  V+  R+     LGE S+   S Y +E       S   KW     P +D + P        G++KV +SV    + P     DD +E     A+L+              + + ++  E L    +N   I   +  + +   G   T+  +E +F         V       + Q+I    ++P  ++ +  ++ D        I    + ++ I   G   E G+LPT+GP+++N++   R   ++   +  +G  Q+   G  + GRL IAI      + +   +     +P+  + ++    E Y  F  +    +IN     +  P+   MSIG  G+  +++    S   P   N              +D  KYF +P+ N +P   +    E    R+ + N++ K+   L  +I        +   H+ S+   ++A   L+      I S  K +  +      A  + +LD + +++++L   +   + +  +++     V  K+      ++ +  ++A D Q  +P + I M+     + +A+I   EI  S    + G  CG    + ++     + + N      A L   +W G    +  +K
Sbjct:  147 IKNQPLEKLAAKVLTLRLVRPTALGESSVGEFSCYLSEVIHSPDRSVIAKWVALGFPGMDDEEPDDIAYENCGFLKVTLSVYRIDESPPTLIDDDGKEQIWSGAHLID-----------YTLKIRVFSVEQLIRQMINERKIKKKQRFYVMVQCGAHKTETTMESAFLDEDANIASVK------FEQEIYLPIQWPTVISEIIFSLFDKKGRGKTCIGKATLPMKMIYEPG---ETGYLPTFGPAFLNVFDCERVTRFSIFSRKMRGSQQD---GSRFVGRLFIAIDCVEYMEKANAQIMHLDHSPIMEAESICKNLEWYNCFCSMSGLNMINPQFASD--PVCIMMSIGSFGSTSNEFRSCNSSTLPAEPN--------------WDGCKYFTMPWGNLRPVAEVNAPWEVIEHRIEMSNVLMKMTNMLDTMIWEVRRIGNKAIDHVSSV--GMEALECLEQQ----IDSASKYLGRINPVSSNALDRHILDYRKEKILKL---REHFEKEAFSIDYSDGEVDAKLLRMLLKIRSMTLELAEDVQMTIPPVLIKMMSHGKLIGFAKIPISEIFQSDDEAQSGEWCGRTRAINIQ-WPTLVDQRNRKREHVAVLHAKMWFGRTDQLTKWK 727          

Query: 5186 GSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAG-TAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKF------PQPAKFYRS---------------------CDPFQLSEACA-------------------------KFNLFRNKKVRGWWPLIYN----------PKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPW------NTIKYFIKY 6109
            GSQ++++    L  ++          LVPE++E+RPL+  +    Q+G L M+VD++P    AIPAP +I PRK I Y+LR  V+       +  +F   E   D++VK+++        KTD H++ L G G FNWRF+ NFDY   E  +V   K+ +     E      L +++ D      D ++G  +  L  F      P     Y +                     C  F     C                            N+F ++ + GWWP++             K  D   +D + I G VE++M L+T +EA+  P G  R+EP       +PD    S+ N W        IKYF  Y
Sbjct: 1508 GSQLQTIALFILRQMN----------LVPEHVESRPLFSDKGGRTQKGELRMFVDIFPMEYGAIPAPFNIAPRKPINYQLRIAVMDVRGAIPVKRSF--AEPVSDLYVKAFINGM-TKGHKTDTHFRVLDGTGEFNWRFLLNFDYNPWEKKVVAYTKNRFFCKPVEELVDPILVIELWDKNKFRKDRLLGDIELDLLDFIEGIGSPSDVGVYSTKKRQRGVKCPKCCTRRGCLCKCCIFCFETKCLCGKRKVKKKPFPKPVLFVEPEGYDDTVNIFESRNLYGWWPMLTEEYPHEEPQNAKKKNDDVGKDPKWIMGLVEMDMLLLTKQEADQEPAGKKRSEPNHSPFLEKPDRK--SWANSWLVSRIKPCIKYFWHY 1869          

Query: 4682 INPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLP-IYDKLTDR 5131
            + P   +VRVYII+A  L  +   G+ D Y+ +  G + V  ++NY  +  +P+FG+ +++ VT P E  L + +    R+  D  IG TTIDLENR L+  + + G+   +   G L+W+D   P  ILKS C +  + +P I  + T+R
Sbjct: 1251 VGPTRCLVRVYIIEANGLISNARKGRVDSYVKLHCGKQNVNLKKNYRSECCDPIFGERVDMTVTIPLEKDLKITVMGKRRILSDQEIGSTTIDLENRLLTKWRATGGLSGQFTVQGELQWRDQMTPMEILKSYCYKMMLSVPKIESRQTER 1401          

Query: 2828 FQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSI-YRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNF-EDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDY-------YQCDQVDNFREIDKTTIDE 3775
            +QLR Y+    +++    +  S  F RI  +++  ++ +   +++PIW+ET++  +++       +   PP V VE+    S+ +E  LG    +P V I G+       QW+ + +      G +LA F+L   +              KD+  +  +   N Y E  E    IP   RP    F  + L WGVR L                K+  +  V +P + + I         + D    PNF E  +VF ++ LP++ +  PP+ IN  ++  F  + +VG+C +++L  Y        + D  + + ++D    +E
Sbjct:  845 WQLRCYIMWGNDLLPVVKNS-SRAFVRISFAQYSKQTLLVDNSQNPIWNETVMFKSVLIAGGTRDIMKYPPVVSVEVVGECSNNEEANLGHFETKPNV-ICGNTDVRGTPQWFPLKFSNGRTRGAVLACFELYSEE-------------DKDLIPLEPKCKHN-YKERSE----IPTEFRPQFDKFHVQFLCWGVRNL----------------KKHKLLAVRRPFVGLTIGDQEFTLQPLKDVRRDPNFPEPMIVFGEVILPSALELSPPLIINLFDARAFNRQPLVGSCLVSDLHKYVSHIVPKVKSDHAERWEQLDLVITEE 1133          

Query:  944 IKIRGLSK-SNNVVAQRIFTGKVLGEFSIDAKSVYTNE-----GHSFFRKWA----PLIDPKSP---TSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDL--PCMNTNIISNIK--HAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPV--SNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDN-KYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEII--------RQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTA-KKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMA-DPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYK 2743
            IK + L K +  V+  R+     LGE S+   S Y +E       S   KW     P +D + P        G++KV +SV    + P     DD +E     A+L+              + + ++  E L    +N   I   +  + +   G   T+  +E +F         V       + Q+I    ++P  ++ +  ++ D        I    + ++ I   G   E G+LPT+GP+++N++   R   ++   +  +G  Q+   G  + GRL IAI      + +   +     +P+  + ++    E Y  F  +    +IN     +  P+   MSIG  G+  +++    S   P   N              +D  KYF +P+ N +P   +    E    R+ + N++ K+   L  +I        +   H+ S+   ++A   L+      I S  K +  +      A  + +LD + +++++L   +   + +  +++     V  K+      ++ +  ++A D Q  +P + I M+     + +A+I   EI  S    + G  CG    + ++     + + N      A L   +W G    +  +K
Sbjct:   20 IKNQPLEKLAAKVLTLRLVRPTALGESSVGEFSCYLSEVIHSPDRSVIAKWVALGFPGMDDEEPDDIAYENCGFLKVTLSVYRIDESPPTLIDDDGKEQIWSGAHLID-----------YTLKIRVFSVEQLIRQMINERKIKKKQRFYVMVQCGAHKTETTMESAFLDEDANIASVK------FEQEIYLPIQWPTVISEIIFSLFDKKGRGKTCIGKATLPMKMIYEPG---ETGYLPTFGPAFLNVFDCERVTRFSIFSRKMRGSQQD---GSRFVGRLFIAIDCVEYMEKANAQIMHLDHSPIMEAESICKNLEWYNCFCSMSGLNMINPQFASD--PVCIMMSIGSFGSTSNEFRSCNSSTLPAEPN--------------WDGCKYFTMPWGNLRPVAEVNAPWEVIEHRIEMSNVLMKMTNMLDTMIWEVRRIGNKAIDHVSSV--GMEALECLEQQ----IDSASKYLGRINPVSSNALDRHILDYRKEKILKL---REHFEKEAFSIDYSDGEVDAKLLRMLLKIRSMTLELAEDVQMTIPPVLIKMMSHGKLIGFAKIPISEIFQSDDEAQSGEWCGRTRAINIQ-WPTLVDQRNRKREHVAVLHAKMWFGRTDQLTKWK 600          

Query: 5186 GSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAG-TAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKF------PQPAKFYRS---------------------CDPFQLSEACA-------------------------KFNLFRNKKVRGWWPLIYN----------PKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPW------NTIKYFIKY 6109
            GSQ++++    L  ++          LVPE++E+RPL+  +    Q+G L M+VD++P    AIPAP +I PRK I Y+LR  V+       +  +F   E   D++VK+++        KTD H++ L G G FNWRF+ NFDY   E  +V   K+ +     E      L +++ D      D ++G  +  L  F      P     Y +                     C  F     C                            N+F ++ + GWWP++             K  D   +D + I G VE++M L+T +EA+  P G  R+EP       +PD    S+ N W        IKYF  Y
Sbjct: 1508 GSQLQTIALFILRQMN----------LVPEHVESRPLFSDKGGRTQKGELRMFVDIFPMEYGAIPAPFNIAPRKPINYQLRIAVMDVRGAIPVKRSF--AEPVSDLYVKAFINGM-TKGHKTDTHFRVLDGTGEFNWRFLLNFDYNPWEKKVVAYTKNRFFCKPVEELVDPILVIELWDKNKFRKDRLLGDIELDLLDFIEGIGSPSDVGVYSTKKRQRGVKCPKCCTRRGCLCKCCIFCFETKCLCGKRKVKKKPFPKPVLFVEPEGYDDTVNIFESRNLYGWWPMLTEEYPHEEPQNAKKKNDDVGKDPKWIMGLVEMDMLLLTKQEADQEPAGKKRSEPNHSPFLEKPDRK--SWANSWLVSRIKPCIKYFWHY 1869          

Query: 4682 INPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLP-IYDKLTDR 5131
            + P   +VRVYII+A  L  +   G+ D Y+ +  G + V  ++NY  +  +P+FG+ +++ VT P E  L + +    R+  D  IG TTIDLENR L+  + + G+   +   G L+W+D   P  ILKS C +  + +P I  + T+R
Sbjct: 1251 VGPTRCLVRVYIIEANGLISNARKGRVDSYVKLHCGKQNVNLKKNYRSECCDPIFGERVDMTVTIPLEKDLKITVMGKRRILSDQEIGSTTIDLENRLLTKWRATGGLSGQFTVQGELQWRDQMTPMEILKSYCYKMMLSVPKIESRQTER 1401          

Query: 2828 FQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSI-YRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNF-EDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDY-------YQCDQVDNFREIDKTTIDE 3775
            +QLR Y+    +++    +  S  F RI  +++  ++ +   +++PIW+ET++  +++       +   PP V VE+    S+ +E  LG    +P V I G+       QW+ + +      G +LA F+L   +              KD+  +  +   N Y E  E    IP   RP    F  + L WGVR L                K+  +  V +P + + I         + D    PNF E  +VF ++ LP++ +  PP+ IN  ++  F  + +VG+C +++L  Y        + D  + + ++D    +E
Sbjct:  845 WQLRCYIMWGNDLLPVVKNS-SRAFVRISFAQYSKQTLLVDNSQNPIWNETVMFKSVLIAGGTRDIMKYPPVVSVEVVGECSNNEEANLGHFETKPNV-ICGNTDVRGTPQWFPLKFSNGRTRGAVLACFELYSEE-------------DKDLIPLEPKCKHN-YKERSE----IPTEFRPQFDKFHVQFLCWGVRNL----------------KKHKLLAVRRPFVGLTIGDQEFTLQPLKDVRRDPNFPEPMIVFGEVILPSALELSPPLIINLFDARAFNRQPLVGSCLVSDLHKYVSHIVPKVKSDHAERWEQLDLVITEE 1133          

Query:  944 IKIRGLSK-SNNVVAQRIFTGKVLGEFSIDAKSVYTNE-----GHSFFRKWA----PLIDPKSP---TSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDL--PCMNTNIISNIK--HAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPV--SNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDN-KYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEII--------RQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTA-KKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMA-DPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYK 2743
            IK + L K +  V+  R+     LGE S+   S Y +E       S   KW     P +D + P        G++KV +SV    + P     DD +E     A+L+              + + ++  E L    +N   I   +  + +   G   T+  +E +F         V       + Q+I    ++P  ++ +  ++ D        I    + ++ I   G   E G+LPT+GP+++N++   R   ++   +  +G  Q+   G  + GRL IAI      + +   +     +P+  + ++    E Y  F  +    +IN     +  P+   MSIG  G+  +++    S   P   N              +D  KYF +P+ N +P   +    E    R+ + N++ K+   L  +I        +   H+ S+   ++A   L+      I S  K +  +      A  + +LD + +++++L   +   + +  +++     V  K+      ++ +  ++A D Q  +P + I M+     + +A+I   EI  S    + G  CG    + ++     + + N      A L   +W G    +  +K
Sbjct:   20 IKNQPLEKLAAKVLTLRLVRPTALGESSVGEFSCYLSEVIHSPDRSVIAKWVALGFPGMDDEEPDDIAYENCGFLKVTLSVYRIDESPPTLIDDDGKEQIWSGAHLID-----------YTLKIRVFSVEQLIRQMINERKIKKKQRFYVMVQCGAHKTETTMESAFLDEDANIASVK------FEQEIYLPIQWPTVISEIIFSLFDKKGRGKTCIGKATLPMKMIYEPG---ETGYLPTFGPAFLNVFDCERVTRFSIFSRKMRGSQQD---GSRFVGRLFIAIDCVEYMEKANAQIMHLDHSPIMEAESICKNLEWYNCFCSMSGLNMINPQFASD--PVCIMMSIGSFGSTSNEFRSCNSSTLPAEPN--------------WDGCKYFTMPWGNLRPVAEVNAPWEVIEHRIEMSNVLMKMTNMLDTMIWEVRRIGNKAIDHVSSV--GMEALECLEQQ----IDSASKYLGRINPVSSNALDRHILDYRKEKILKL---REHFEKEAFSIDYSDGEVDAKLLRMLLKIRSMTLELAEDVQMTIPPVLIKMMSHGKLIGFAKIPISEIFQSDDEAQSGEWCGRTRAINIQ-WPTLVDQRNRKREHVAVLHAKMWFGRTDQLTKWK 600          

Query: 4709 VYIIKAINLHPSDLNGKSDPYILVK--LGDKEVRDRENYIPKT-LNPVFGKCIELEVTFPQ--ESFLLVQIYDWDRLTKDDLIG 4945
            + + KA NL P D+ G SDPY+ ++     K  + +++   +  LNPVF + +  ++   Q  E+ +L+Q+ DWDR+ KDDL+G
Sbjct:  286 INVSKAYNLRPMDITGASDPYVKIEQTFNGKRFKSKKSSTKRANLNPVFHETLVFDIPSSQIAETNILIQVMDWDRIGKDDLLG 369          

Query: 4709 VYIIKAINLHPSDLNGKSDPYILVK--LGDKEVRDRENYIPKT-LNPVFGKCIELEVTFPQ--ESFLLVQIYDWDRLTKDDLIG 4945
            + + KA NL P D+ G SDPY+ ++     K  + +++   +  LNPVF + +  ++   Q  E+ +L+Q+ DWDR+ KDDL+G
Sbjct:  251 INVSKAYNLRPMDITGASDPYVKIEQTFNGKRFKSKKSSTKRANLNPVFHETLVFDIPSSQIAETNILIQVMDWDRIGKDDLLG 334          

Query: 4691 VDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFI 6103
            V  +VRVY+++ + + P D+ G SD Y+ + LG K   DR ++ P   NPVFG+  E+E T P +  L V +YD D++ KD++IG+T IDLE+RW + H+ + G+   Y   GY  W D +LP+ IL  LC++  +  P Y    + +++D   F  ET+I  D+  Q    E L+L VL +  ++   G KLVPE++ETR L   + P ++QG L++W++++ A   +P+PIDITP     +E+R  V     ++  + N F  +   D++V  W +  D   Q TD+HY+S +G   FNWR V+   Y   ED +V  +K+   ++E E+K P  + +QV D  ++  D  +   +  LS    P    + C P+   +   + NLF+ K + GW+PL  N       +   +     ++L +E+ T  EA + P G G+  PM LE P RPD SF    +P  + ++ +
Sbjct:  153 VKLLVRVYVVQGVQMRPRDVKGDSDCYVKLFLGGKTFSDRAHFSPNHSNPVFGRLFEMEATLPGDHMLQVMVYDHDKI-KDEVIGQTNIDLEDRWRTRHRATVGLANEYTKSGYNHWHDVKLPSEILIDLCQKRGIQAPYY--YGNVIEVDGMLFGDETLISKDEELQ----ERLSLAVLKNMDKLPSFGYKLVPEHVETRSLCRDDFPNVEQGKLQLWIELFEANIYVPSPIDITPVPPADFEVRVVVKNLVGIQAGDKNIF-GKLMSDVYVIGWCEDED-KRQSTDIHYRSFAGDAAFNWRMVFGLKYSPNEDLMVIRRKAGL-LEEIEFKKPPIIYLQVWDKDVLTKDEYLAALELNLSNMYAPYPAAQLCKPY--PKKRKRINLFKRKVINGWFPLQSNAHPSQRSQAAVQNGK--MQLSIEVCTDVEAVNRPAGRGQDPPMALEPPYRPDSSFNPLTHPCKSFQHIL 610          

Query: 4691 VDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFI 6103
            V  +VRVY+++ + + P D+ G SD Y+ + LG K   DR ++ P   NPVFG+  E+E T P +  L V +YD D++ KD++IG+T IDLE+RW + H+ + G+   Y   GY  W D +LP+ IL  LC++  +  P Y    + +++D   F  ET+I  D+  Q    E L+L VL +  ++   G KLVPE++ETR L   + P ++QG L++W++++ A   +P+PIDITP     +E+R  V     ++  + N F  +   D++V  W +  D   Q TD+HY+S +G   FNWR V+   Y   ED +V  +K+   ++E E+K P  + +QV D  ++  D  +   +  LS    P    + C P+   +   + NLF+ K + GW+PL  N       +   +     ++L +E+ T  EA + P G G+  PM LE P RPD SF    +P  + ++ +
Sbjct:  856 VKLLVRVYVVQGVQMRPRDVKGDSDCYVKLFLGGKTFSDRAHFSPNHSNPVFGRLFEMEATLPGDHMLQVMVYDHDKI-KDEVIGQTNIDLEDRWRTRHRATVGLANEYTKSGYNHWHDVKLPSEILIDLCQKRGIQAPYY--YGNVIEVDGMLFGDETLISKDEELQ----ERLSLAVLKNMDKLPSFGYKLVPEHVETRSLCRDDFPNVEQGKLQLWIELFEANIYVPSPIDITPVPPADFEVRVVVKNLVGIQAGDKNIF-GKLMSDVYVIGWCEDED-KRQSTDIHYRSFAGDAAFNWRMVFGLKYSPNEDLMVIRRKAGL-LEEIEFKKPPIIYLQVWDKDVLTKDEYLAALELNLSNMYAPYPAAQLCKPY--PKKRKRINLFKRKVINGWFPLQSNAHPSQRSQAAVQNGK--MQLSIEVCTDVEAVNRPAGRGQDPPMALEPPYRPDSSFNPLTHPCKSFQHIL 1313          

Query: 4691 VDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFI 6103
            V  +VRVY+++ + + P D+ G SD Y+ + LG K   DR ++ P   NPVFG+  E+E T P +  L V +YD D++ KD++IG+T IDLE+RW + H+ + G+   Y   GY  W D +LP+ IL  LC++  +  P Y    + +++D   F  ET+I  D+  Q    E L+L VL +  ++   G KLVPE++ETR L   + P ++QG L++W++++ A   +P+PIDITP     +E+R  V     ++  + N F  +   D++V  W +  D   Q TD+HY+S +G   FNWR V+   Y   ED +V  +K+   ++E E+K P  + +QV D  ++  D  +   +  LS    P    + C P+   +   + NLF+ K + GW+PL  N       +   +     ++L +E+ T  EA + P G G+  PM LE P RPD SF    +P  + ++ +
Sbjct:  944 VKLLVRVYVVQGVQMRPRDVKGDSDCYVKLFLGGKTFSDRAHFSPNHSNPVFGRLFEMEATLPGDHMLQVMVYDHDKI-KDEVIGQTNIDLEDRWRTRHRATVGLANEYTKSGYNHWHDVKLPSEILIDLCQKRGIQAPYY--YGNVIEVDGMLFGDETLISKDEELQ----ERLSLAVLKNMDKLPSFGYKLVPEHVETRSLCRDDFPNVEQGKLQLWIELFEANIYVPSPIDITPVPPADFEVRVVVKNLVGIQAGDKNIF-GKLMSDVYVIGWCEDED-KRQSTDIHYRSFAGDAAFNWRMVFGLKYSPNEDLMVIRRKAGL-LEEIEFKKPPIIYLQVWDKDVLTKDEYLAALELNLSNMYAPYPAAQLCKPY--PKKRKRINLFKRKVINGWFPLQSNAHPSQRSQAAVQNGK--MQLSIEVCTDVEAVNRPAGRGQDPPMALEPPYRPDSSFNPLTHPCKSFQHIL 1401          

Query: 1376 YVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSN-TVAGKREMYLLFGGIYETTLINEDLGKNGKP-LTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPR----MFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSG------VKSCRGT--AKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLE--DKMADPQYGLPDIFIYMIQENIRVAYARIKAREII---HSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGL-PEGYNRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLG 3097
            +++  F  + G+T VV    +P WN +I F   +P    R  I +  ++ ++ + ++   + L++I + G+       P+ GP++++LY                    +    + Y GRL++ ++       S++  D +P + +S+ TV G  E       +Y    + E L   G   LT   +  I+  L +  + V   +  TP +++  +M    F           P+++   C+F + +  D+R +     F+ +I+  ++ EL +  +       L+ + QA + LK  + N++  I++ +        V+  R T    + +  + Y   + L+L+ +K KL++  LE   +++ + + E   LV  +     MA  Q   P++ + +      V   R+ A+  +   +     ++  +C  + +   K    S    N      A +   L + + R+ + +   +  E  N E    ++ P      +++ F   VY+  A+   G +   + D   R++ ++   ++     T SPIW+  +  + +       +   +PP + +E ++ +    E+ +G
Sbjct:    4 FLKYRFHPFKGKTPVVKNTTTPVWNYEINFAWMYPSVAQRFLILIFAHEHLQWKCVAEFELCLEEIAFNGT-------PSLGPTYLHLY--------------------DPVNPMIYVGRLLMELR-------SEMLTDSQPTHTLSSKTVPGLDETRFWHDDVY----LIEFLPLMGHHILTSGTAYKISARLAEHTSNVLEGQLRTPLDRFKSAMNSKNFRR-------EAPFQS---CMFRV-RLPDNRAKYESDFFMLDIVNYMRSEL-DTFKLFQRKYPLQDDEQA-KCLKVIVNNILTRIKEGLDAHRFDHDVQPQRTTWDINRQLYLLDYFAKLPLELQNLKQKLRSCFLEHLDTSIGDVVNELQRLVAEIGSLSSMARTQDEWPELVLSLSASGKDVGVCRLNAKLFLNLRNQDADQDQETLCWRLKSFSFKSAGCSHTCPNCGCTT-AIVSGCLSIVVERERKRFLAVVNKEWANIEPMLWQLNP------EQTHFLCHVYIHQAKVRPGGEKKNICDSHLRVLFADQACETYTSPGTLSPIWNAVITFNWVSLPGGIGLYLKNPPLLSLEFYNSERSLPEDLVG 539          

Query: 4691 VDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFI 6103
            V  +VRVY+++ + + P D+ G SD Y+ + LG K   DR ++ P   NPVFG+  E+E T P +  L V +YD D++ KD++IG+T IDLE+RW + H+ + G+   Y   GY  W D +LP+ IL  LC++  +  P Y    + +++D   F  ET+I  D+  Q    E L+L VL +  ++   G KLVPE++ETR L   + P ++QG L++W++++ A   +P+PIDITP     +E+R  V     ++  + N F  +   D++V  W +  D   Q TD+HY+S +G   FNWR V+   Y   ED +V  +K+   ++E E+K P  + +QV D  ++  D  +   +  LS    P    + C P+   +   + NLF+ K + GW+PL  N       +   +     ++L +E+ T  EA + P G G+  PM LE P RPD SF    +P  + ++ +
Sbjct: 1152 VKLLVRVYVVQGVQMRPRDVKGDSDCYVKLFLGGKTFSDRAHFSPNHSNPVFGRLFEMEATLPGDHMLQVMVYDHDKI-KDEVIGQTNIDLEDRWRTRHRATVGLANEYTKSGYNHWHDVKLPSEILIDLCQKRGIQAPYY--YGNVIEVDGMLFGDETLISKDEELQ----ERLSLAVLKNMDKLPSFGYKLVPEHVETRSLCRDDFPNVEQGKLQLWIELFEANIYVPSPIDITPVPPADFEVRVVVKNLVGIQAGDKNIF-GKLMSDVYVIGWCEDED-KRQSTDIHYRSFAGDAAFNWRMVFGLKYSPNEDLMVIRRKAGL-LEEIEFKKPPIIYLQVWDKDVLTKDEYLAALELNLSNMYAPYPAAQLCKPY--PKKRKRINLFKRKVINGWFPLQSNAHPSQRSQAAVQNGK--MQLSIEVCTDVEAVNRPAGRGQDPPMALEPPYRPDSSFNPLTHPCKSFQHIL 1609          

Query:  749 EDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKI---RGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTS------GEKGYVKVDISVLCAGDKPKRPDADDNEENPN------------IEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNII--SNIKH--AIY-GEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSN-TVAGKREMYLLFGGIYETTLINEDLGKNGKP-LTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPR----MFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSG------VKSCRGT--AKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLE--DKMADPQYGLPDIFIYMIQENIRVAYARIKAREII---HSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGL-PEGYNRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLG 3097
            ++F I +T+ +A  +          +   K  ++T+    T +PF+NE+F F+   +  E++ L I     + ++   NVV         +GE  +D  SV+    H +F+KW  L  P              GY+++D++++            + ++  N            IE NLL                            N NI   SNI++  A Y G     ++  ++VSFAG+ G+T VV    +P WN +I F   +P    R  I +  ++ ++ + ++   + L++I + G+       P+ GP++++LY                    +    + Y GRL++ ++       S++  D +P + +S+ TV G  E       +Y    + E L   G   LT   +  I+  L +  + V   +  TP +++  +M    F           P+++   C+F + +  D+R +     F+ +I+  ++ EL +  +       L+ + QA + LK  + N++  I++ +        V+  R T    + +  + Y   + L+L+ +K KL++  LE   +++ + + E   LV  +     MA  Q   P++ + +      V   R+ A+  +   +     ++  +C  + +   K    S    N      A +   L + + R+ + +   +  E  N E    ++ P      +++ F   VY+  A+   G +   + D   R++ ++   ++     T SPIW+  +  + +       +   +PP + +E ++ +    E+ +G
Sbjct:   13 QEFLICITVHKAAQVGVTTGELYVRISLDKMTKSTKSFPNTENPFFNEYFVFEFHCTLTELLRLTILFELKKHMTYKKNVV---------VGELLVDLHSVWNQSNHGYFKKWGRLEAPIGENQTLENAVAPHGYLQLDLAIVSQHSPVSYALGSEEQDTQNLNKWTVDHDFDDIEKNLLT---------------------------NVNIFAPSNIRYFVAFYRGYFIKQSNYMIQVSFAGFNGKTPVVKNTTTPVWNYEINFAWMYPSVAQRFLILIFAHEHLQWKCVAEFELCLEEIAFNGT-------PSLGPTYLHLY--------------------DPVNPMIYVGRLLMELR-------SEMLTDSQPTHTLSSKTVPGLDETRFWHDDVY----LIEFLPLMGHHILTSGTAYKISARLAEHTSNVLEGQLRTPLDRFKSAMNSKNFRR-------EAPFQS---CMFRV-RLPDNRAKYESDFFMLDIVNYMRSEL-DTFKLFQRKYPLQDDEQA-KCLKVIVNNILTRIKEGLDAHRFDHDVQPQRTTWDINRQLYLLDYFAKLPLELQNLKQKLRSCFLEHLDTSIGDVVNELQRLVAEIGSLSSMARTQDEWPELVLSLSASGKDVGVCRLNAKLFLNLRNQDADQDQETLCWRLKSFSFKSAGCSHTCPNCGCTT-AIVSGCLSIVVERERKRFLAVVNKEWANIEPMLWQLNP------EQTHFLCHVYIHQAKVRPGGEKKNICDSHLRVLFADQACETYTSPGTLSPIWNAVITFNWVSLPGGIGLYLKNPPLLSLEFYNSERSLPEDLVG 747          

Query: 4691 VDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAP 6040
            V  +VRVY+++ + + P D+ G SD Y+ + LG K   DR ++ P   NPVFG+  E+E T P +  L V +YD D++ KD++IG+T IDLE+RW + H+ + G+   Y   GY  W D +LP+ IL  LC++  +  P Y    + +++D   F  ET+I  D+  Q    E L+L VL +  ++   G KLVPE++ETR L   + P ++QG L++W++++ A   +P+PIDITP     +E+R  V     ++  + N F  +   D++V  W +  D   Q TD+HY+S +G   FNWR V+   Y   ED +V  +K+   ++E E+K P  + +QV D  ++  D  +   +  LS    P    + C P+   +   + NLF+ K + GW+PL  N       +   +     ++L +E+ T  EA + P G G+  PM LE P
Sbjct:  609 VKLLVRVYVVQGVQMRPRDVKGDSDCYVKLFLGGKTFSDRAHFSPNHSNPVFGRLFEMEATLPGDHMLQVMVYDHDKI-KDEVIGQTNIDLEDRWRTRHRATVGLANEYTKSGYNHWHDVKLPSEILIDLCQKRGIQAPYY--YGNVIEVDGMLFGDETLISKDEELQ----ERLSLAVLKNMDKLPSFGYKLVPEHVETRSLCRDDFPNVEQGKLQLWIELFEANIYVPSPIDITPVPPADFEVRVVVKNLVGIQAGDKNIF-GKLMSDVYVIGWCEDED-KRQSTDIHYRSFAGDAAFNWRMVFGLKYSPNEDLMVIRRKAGL-LEEIEFKKPPIIYLQVWDKDVLTKDEYLAALELNLSNMYAPYPAAQLCKPY--PKKRKRINLFKRKVINGWFPLQSNAHPSQRSQAAVQNGK--MQLSIEVCTDVEAVNRPAGRGQDPPMALEPP 1045          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVA----------------------SEKEPTPENQYVHSM--TQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENK---LRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P S +  D+QISVT++EAR L G N++P+  V  G++K+ T +K  TN P+YNE+F FD  +    M + IIKI  +   N      + +G ++G F +D  +VYT   H F  KWA L DP   T+G KGYVK DI+V+  GD  K P      +  +IE NLL+P  V  + R+     V IY+AE LP MNT+I++N+K A  GE + L D YV V FAG  G+T V   +Y P WN+Q+IFTE FPP   RL++ +RD+D V D  I T FIDL+K+   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RL+I+I      T+     S   V + P + +S +  GK E + LFG   E T+I+  +G   KP++FE++IG  GN +D  +K A                      S +E   ++  + S+  T        D  YFH+PY  KKPC+++ +  +D R R++  NI++K+  +L E +     +I  EK    RR L+  +  L  S  + V+     +  + +T LD +  +    ++E M  + + +  ++KR+ V +K++     ++ L     +PQ+ +PD+FI+MI  N R+AYARI +++I++S +  E G  CG +  V+L RL          + +QA+L++YLWLGL +  + + +GLP G+   +   G     +PP  + Y  + +FQLR +++ AR++  +D SGLSDPFAR+  S H   + + ++T  P WD+ L+ DN+        L+  PP +V+E++D D+    EF+GR F +P   +  + Y   +    L+++ IYRG  AAG++LAAF+L+++    +      LP +               G  D ++   L +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+T L
Sbjct:  249 MEPSSGRPVDYQISVTVIEARQLVGLNMDPVVCVEIGEEKKYTSMKESTNCPYYNEYFVFDFHVPPDVMFDKIIKISVIHSKN-----LLRSGTLVGTFKLDVGTVYTQPEHQFHHKWAMLSDPDDITTGCKGYVKCDIAVVGKGDNIKTPHKASEADEDDIEGNLLLPEGVP-SERQWARFYVKIYRAEGLPKMNTSIMANVKKAFIGENRDLVDPYVLVQFAGQKGKTSVQKSSYEPIWNEQVIFTEMFPPLCRRLKVQIRDSDKVNDVAIGTHFIDLRKVSNDGDK---GFLPTMGPAWVNMYGSTRNYT---LMDEHQDLNEGLGEGVSFRARLLISIAVEILDTTSAEIMSSTEVHMEPVSNISESATGKMEEFFLFGSFLEATMIDRKIGD--KPISFEVTIGNYGNQIDGVSKPALAKKKKEGGGESEEEESELIHNSSEEEAEDDGDLTSVPSTPPMKPVITDRNYFHLPYFEKKPCIYIKSWWQDQRRRLYNSNIMDKIADKLEEGLNDVQEIIKTEKAYPERR-LRGVLEELSTSCSRFVTLANKDQNLSGRTKLDRERLKSCMREMESMGQQAKTIRTQVKRNTVRDKLKLVLNFLQRLRFLADEPQHSIPDVFIWMISNNKRIAYARIPSKDILYSIVDEEMGKDCGKVKAVFL-RLPGKKGFGPAGWTVQAKLEMYLWLGLNKQRKDFLIGLPSGFEENKAVKGIGIQAVPPISLVYNMKQVFQLRAHMYQARSLFAADTSGLSDPFARVFFSTHSQVTEVLSETLCPTWDQLLVFDNVELYGEAGELRDDPPIIVIELYDQDTVGKAEFIGRTFAKPLTKMVDEHYGPPRFPPQLEYYQIYRGNCAAGDLLAAFELLQIGPAGR----AALPPID--------------GPTDSDRGPILPVPLGIRPVLSRYRIEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSALIQNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYILVGSHAVTTL 1234          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDD-NFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAP-IDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC--DPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            ++ +M+Y  ELE+  +FG F D   +F+LYRGK  +DDD N  + DR  G FKG++C+Y +   +    +   +                                     + +++++   +P++ +VR+YII+A +LHP+D+NGK+DPYI++KLG  ++RD+ENYI K LNPVFGK  ++E TFP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D + P  IL  LC+E  +  P Y     RV + +R F   T IED+ G + ++ E LAL VL HW EI   G KL+PE++ETRPL  P+KPGI+QG +EMWVDM+P     P P IDI+PRK   YELR  +  T++V L + ++FT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWRFV+ FDYL AE+ IV ++K S++  DE EYK P  L +QV D+    +D  +G  +  L+KFP+ AK  + C  D           ++F+ K+V+GWWP +   ++++ +          VE E+ L+TAEEAE +PVGLGR +P PLE P RPD +FL FL+P   I+Y I  R KW++IKI +  + L+++ LF+Y+ PG     +V K+ G
Sbjct: 1399 VDELMVYNKELES--EFGSFEDWLHTFNLYRGKAGDDDDHNVVDEDRIVGRFKGSLCMYKLPLSEEITREAGFDP-----------------------------------NMGMFQSIPHNDPINVLVRIYIIRATDLHPADINGKADPYIVIKLGKSDIRDKENYISKQLNPVFGKSFDIEATFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRYYSKHRATCGIASNYSVHGYNVWRDPQKPAQILAKLCKEGKLDGPHYGP-GGRVKVANRIFLGPTEIEDESGLKKQTEEHLALTVLRHWEEIPRVGCKLIPEHVETRPLLNPDKPGIEQGRIEMWVDMFPMDVPAPGPAIDISPRKPKRYELRVIIWNTDEVILEDDDYFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFVFPFDYLMAEEKIVISKKESMFSWDETEYKIPARLTLQVWDADHFSADDFLGAIELDLNKFPRGAKTAKQCSLDMVLKEHELPTISIFKQKRVKGWWPFVAQNENDEFELTGK------VEAELHLLTAEEAEKSPVGLGRNDPEPLEKPNRPDTTFLWFLSPLKAIRYLICNRYKWLIIKIVLALLLLIMVGLFLYSMPG----YLVKKLLG 1991          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSAN-IYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEY 487
            M+L V+LK +      GD+  K+ FR +   S  L+   +   F Q F WPI  ++D +++L ++ +N ++V  ++L+G  ++    ++ E  + V + L+D+        ++ EI+Y
Sbjct:    1 MALVVHLKTVTELRGKGDRIAKVTFRGLSFFSRVLENCEDEARFEQAFRWPIGSQVDGDEMLEIQVFNYSKVFTNRLIGTFRMVLQKVVEEGHLEVSDTLIDDNNTAIQTTISIEIKY 118          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVA----------------------SEKEPTPENQYVHSM--TQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENK---LRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P S +  D+QISVT++EAR L G N++P+  V  G++K+ T +K  TN P+YNE+F FD  +    M + IIKI  +   N      + +G ++G F +D  +VYT   H F  KWA L DP   T+G KGYVK DI+V+  GD  K P      +  +IE NLL+P  V  + R+     V IY+AE LP MNT+I++N+K A  GE + L D YV V FAG  G+T V   +Y P WN+Q+IFTE FPP   RL++ +RD+D V D  I T FIDL+K+   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RL+I+I      T+     S   V + P + +S +  GK E + LFG   E T+I+  +G   KP++FE++IG  GN +D  +K A                      S +E   ++  + S+  T        D  YFH+PY  KKPC+++ +  +D R R++  NI++K+  +L E +     +I  EK    RR L+  +  L  S  + V+     +  + +T LD +  +    ++E M  + + +  ++KR+ V +K++     ++ L     +PQ+ +PD+FI+MI  N R+AYARI +++I++S +  E G  CG +  V+L RL          + +QA+L++YLWLGL +  + + +GLP G+   +   G     +PP  + Y  + +FQLR +++ AR++  +D SGLSDPFAR+  S H   + + ++T  P WD+ L+ DN+        L+  PP +V+E++D D+    EF+GR F +P   +  + Y   +    L+++ IYRG  AAG++LAAF+L+++    +      LP +               G  D ++   L +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+T L
Sbjct:  249 MEPSSGRPVDYQISVTVIEARQLVGLNMDPVVCVEIGEEKKYTSMKESTNCPYYNEYFVFDFHVPPDVMFDKIIKISVIHSKN-----LLRSGTLVGTFKLDVGTVYTQPEHQFHHKWAMLSDPDDITTGCKGYVKCDIAVVGKGDNIKTPHKASEADEDDIEGNLLLPEGVP-SERQWARFYVKIYRAEGLPKMNTSIMANVKKAFIGENRDLVDPYVLVQFAGQKGKTSVQKSSYEPIWNEQVIFTEMFPPLCRRLKVQIRDSDKVNDVAIGTHFIDLRKVSNDGDK---GFLPTMGPAWVNMYGSTRNYT---LMDEHQDLNEGLGEGVSFRARLLISIAVEILDTTSAEIMSSTEVHMEPVSNISESATGKMEEFFLFGSFLEATMIDRKIGD--KPISFEVTIGNYGNQIDGVSKPALAKKKKEGGGESEEEESELIHNSSEEEAEDDGDLTSVPSTPPMKPVITDRNYFHLPYFEKKPCIYIKSWWQDQRRRLYNSNIMDKIADKLEEGLNDVQEIIKTEKAYPERR-LRGVLEELSTSCSRFVTLANKDQNLSGRTKLDRERLKSCMREMESMGQQAKTIRTQVKRNTVRDKLKLVLNFLQRLRFLADEPQHSIPDVFIWMISNNKRIAYARIPSKDILYSIVDEEMGKDCGKVKAVFL-RLPGKKGFGPAGWTVQAKLEMYLWLGLNKQRKDFLIGLPSGFEENKAVKGIGIQAVPPISLVYNMKQVFQLRAHMYQARSLFAADTSGLSDPFARVFFSTHSQVTEVLSETLCPTWDQLLVFDNVELYGEAGELRDDPPIIVIELYDQDTVGKAEFIGRTFAKPLTKMVDEHYGPPRFPPQLEYYQIYRGNCAAGDLLAAFELLQIGPAGR----AALPPID--------------GPTDSDRGPILPVPLGIRPVLSRYRIEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSALIQNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYILVGSHAVTTL 1234          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDD-NFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAP-IDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC--DPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            ++ +M+Y  ELE+  +FG F D   +F+LYRGK  +DDD N  + DR  G FKG++C+Y +   +    +   +                                     + +++++   +P++ +VR+YII+A +LHP+D+NGK+DPYI++KLG  ++RD+ENYI K LNPVFGK  ++E TFP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D + P  IL  LC+E  +  P Y     RV + +R F   T IED+ G + ++ E LAL VL HW EI   G KL+PE++ETRPL  P+KPGI+QG +EMWVDM+P     P P IDI+PRK   YELR  +  T++V L + ++FT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWRFV+ FDYL AE+ IV ++K S++  DE EYK P  L +QV D+    +D  +G  +  L+KFP+ AK  + C  D           ++F+ K+V+GWWP +   ++++ +          VE E+ L+TAEEAE +PVGLGR +P PLE P RPD S + F+NP  +I+YFI +  +W+++K   + + LL++ LF+Y+ PG     +V K+ G
Sbjct: 1399 VDELMVYNKELES--EFGSFEDWLHTFNLYRGKAGDDDDHNVVDEDRIVGRFKGSLCMYKLPLSEEITREAGFDP-----------------------------------NMGMFQSIPHNDPINVLVRIYIIRATDLHPADINGKADPYIVIKLGKSDIRDKENYISKQLNPVFGKSFDIEATFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRYYSKHRATCGIASNYSVHGYNVWRDPQKPAQILAKLCKEGKLDGPHYGP-GGRVKVANRIFLGPTEIEDESGLKKQTEEHLALTVLRHWEEIPRVGCKLIPEHVETRPLLNPDKPGIEQGRIEMWVDMFPMDVPAPGPAIDISPRKPKRYELRVIIWNTDEVILEDDDYFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFVFPFDYLMAEEKIVISKKESMFSWDETEYKIPARLTLQVWDADHFSADDFLGAIELDLNKFPRGAKTAKQCSLDMVLKEHELPTISIFKQKRVKGWWPFVAQNENDEFELTGK------VEAELHLLTAEEAEKSPVGLGRNDPEPLEKPNRPDTSLMWFMNPLRSIRYFIWHNYRWLILKALALLLLLLLVGLFLYSIPG----YLVKKLLG 1991          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSAN-IYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEY 487
            M+L V+LK +      GD+  K+ FR +   S  L+   +   F Q F WPI  ++D +++L ++ +N ++V  ++L+G  ++    ++ E  + V + L+D+        ++ EI+Y
Sbjct:    1 MALVVHLKTVTELRGKGDRIAKVTFRGLSFFSRVLENCEDEARFEQAFRWPIGSQVDGDEMLEIQVFNYSKVFTNRLIGTFRMVLQKVVEEGHLEVSDTLIDDNNTAIQTTISIEIKY 118          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEP----TPENQYVH----------------SMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENK---LRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            I+P + +  DFQ+SVT++EAR L G N++P+  V  G  K+ T +K  TN P+YNE+F FD  +    M + I+K+  +   N      + +G ++G F +D  ++YT   H FF KWA L DP+  T+G KGYVK DI+V+  GD  K P   +  +  +IE+NLL+P  V    R+     + IY+AE LP MNT+I++N+K A  GE K L D YV+V FAG  G+T +   +Y P WN+QI+FTE+FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R++T   L+   Q  N+ L EGV++R RL+I++      TS     S   V V     +S+   GK E + LFG   E T+I+  +G   KP+ FE++IG  G+ LD   K  S+K+       E++ +H                S T        D  YFH+PY  +KPC+++ +  +D R R++  N+++K+  +L E +     +I  EK    RR L+  +  L  S    VS   + +  A +T LD +  +L   ++E M  + + +  ++K+SNV ++++     +  L     +PQ+ +PDI+I+MI  N R+AYAR+ +++I++SS+  E G  CG + T++ K L          + +QA+ ++YLWLGL R  + Y  GLP G+   +   G      PP  + Y  + +FQLRV+++ AR++  +D +GLSDPFARI  S H   + +  +T  P WD+ L+ D++        L+  PP +V+EI+D D+    +F+GR F +P   +  + Y   +    L+++ IYRG   AGE+LAAF+L+++    K      LP +               G  D ++   L +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+T L
Sbjct:   58 IEPSAGRPMDFQVSVTVIEARQLVGLNMDPVVCVEIGDDKKYTSMKESTNCPYYNEYFVFDFHVPPDVMFDKILKVSVIHSKN-----LLRSGTLVGSFKLDVGTIYTQPDHQFFHKWATLCDPEDITAGLKGYVKCDIAVVAKGDTIKTPHKANENDEDDIESNLLLPEDVP-AERQWARFYLKIYRAEGLPKMNTSIMANVKKAFIGENKDLVDPYVQVLFAGQKGKTSIQKSSYEPIWNEQIVFTEQFPPLCRRMKLQIRDSDKVNDVAIGTHFIDLRKIANDGDK---GFLPTLGPAWVNMYGSTRSYT---LMDEYQDLNEGLGEGVSFRARLLISLAVEILDTSSPEVMSSTEVQVEGIPNISDNATGKVEEFFLFGSFLEATMIDRKIGD--KPINFEVTIGNYGSELDTPTKPKSKKKKGDGDDEESELIHGSSDEEVDDGGDVTSVSTTPPMKPVITDRNYFHLPYFERKPCIYIYSWWQDQRRRLYNANVLDKMADKLEEGLNDVQEIIKTEKAYPERR-LRGVLEELSNSCSTFVSLANNDQNQAGRTKLDKERVKLCMQEVESMGQQAKTMRSQVKKSNVKDRIKLAQNFLHKLRFLSDEPQHSVPDIYIWMISNNKRIAYARVPSKDILYSSVEEECGKDCGKVQTIFFK-LPGKKSFGPAGWTVQAKTELYLWLGLNRQRKDYLCGLPNGFEENKAVKGPGVQSSPPISLMYTMKQIFQLRVHMYQARSLFAADSTGLSDPFARIFFSTHSQVTEVLNETLCPTWDQLLVFDHVELYGEAGELRDDPPIIVIEIYDQDTVGKADFMGRTFAKPITKMSDEHYGPPRFPPQLEYYQIYRGNCTAGEMLAAFELLQIGPGGK----ADLPPID--------------GPTDIDRGPILPVPIGIRPVLSKYRIEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSSLIQNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVTTL 1039          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEED---DDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAP-IDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLS--EACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            IE   +Y  ELE   ++  F D   +F+L+RGK  +D   D N  + DR  G FKG++CIY +  +D       +                                      + +++N+   +P++ +VR+Y+++A +LHP+D+NGK+DPYI +KLG  E++D+ENYI K LNPVFGK  ++E T P +S L V IYDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   P+ IL  LC++  +  P Y     RV + +R +   T +ED++G + ++ E LAL VL+HW +I   G KLVPE++ETRPL  P+KPGI+QG +EMWVDM+P   + P P +DI+PRK   +ELR  V  T++V L + + FT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWRF+Y FDYL+AE+ IV ++K S++  DE EYK P  LN+QV D+    +D  +G  +  L++FP+ AK  + C    ++        N+F+ K+++GWWP +   ++++ +          VE E++L+T EEAE +PVG GR EP PLE P RPD +FL F+ P   I++ +  + KW++IKI V  + L ++ LF+Y+ PG     +V K+ G
Sbjct: 1179 IEEFKVYNRELE--YEYNQFEDWLHTFNLHRGKCSDDADVDQNAADEDRLIGKFKGSLCIYKVSSDDMSRDMGFDS------------------------------------NMGMFQNIPHNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKSEIKDKENYISKQLNPVFGKSFDVEATLPMDSTLTVSIYDWDLVGTDDLIGETKIDLENRFYSKHRATCGISSTYAIHGYNVWRDPLKPSHILAKLCKDGKIDAPQYGP-GGRVKVTNRVYTGPTEVEDENGLKKQTDEHLALAVLNHWEDIPRIGCKLVPEHMETRPLLNPDKPGIEQGRIEMWVDMFPKDMSAPGPALDISPRKPKKFELRVIVWNTDEVVLEDDDIFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFIYPFDYLQAEEKIVISKKESMFSWDETEYKIPARLNLQVWDADHFSADDFLGAIELDLNRFPRGAKTAKQCSIEMVTNENEMPMVNIFKQKRIKGWWPFVARDENDELEITGK------VEAELQLLTGEEAEKSPVGEGRNEPEPLEKPNRPDTAFLWFMMPLKAIRHLVCNQYKWLVIKIVVALLLLAMLGLFLYSMPG----YMVKKLLG 1772          

Query:  743 KIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGD-KPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK---------------TSYQP-----------------DSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKE-----------PTPENQYVHSMTQSRFAYTYDNK--YFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHL--------ISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSN--VYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGK----MPPKYIDYLDES-MFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLV 3712
            K ++FQIS+ I E R L G+NI+P   +  G  K+ T +K  TN+PFYNE+F FD+  ++    + +IK+       +V+  +I     +G F ID  +VY+  GH F  KWA L DP     G KGY+K DISV   GD  P      D EE   I+ +LL+P  + N  R      V++Y+AE LP +N++I++N+  A  G+  AL D YVEVSF G  GRT     +  P WN+Q++F E FPP   RL+I V D   + D  I T +IDL  I    +  + GFLPT+GP+WINLYG+ R  T   L+   Q  N+ + EGV+YRGRL I +                + + P                  S  IG +V P  P         E +LLFG ++E ++I+  +G   +P+T E +IG  GNL+D  A   S+K+            T       S T        D +  Y H+P   +KPC+++ +  ED   R+   N+++ +     E + + + L         SL  +V   R  +      I   EK V G       +  T+LD K   + + +LE M  ++    LE KR +  V E + E   + K L   + +PQ+ LPD+F+ ++  N RVAYARI AR+++ S    ++G  CG + T++LK      +K    + +QA+L ++LWLG   +       LP G+     S +     PP+Y+ Y  ++ MF+LR +++ AR +I +D++GLSDPFA +    H   + I  QT +P W++ + + N+        +   PP +V+E++D D     E+LG     P V +  +QY+  +LQ+  ++ G+L+ G+IL AF+L++    +       LP +                E D   + +P +IRP L  +R E+L WG+R+L++++++                 V++P++ I  AG  + S  I  +   PNF   +   D+ LP      PP+ +   +   FG   +VG+  I NL 
Sbjct:  102 KPQNFQISINITEIRQLVGDNIDPSVVIEIGDDKKQTSVKEGTNAPFYNEYFVFDIYCNQDIFFDKVIKL-------SVMHSKIMKSYCVGTFKIDVGTVYSQPGHQFINKWATLTDPADIRVGVKGYLKCDISVSGKGDVAPPSQKFSDAEEQ--IDKHLLLPEGL-NPERPWARFYVIVYRAEGLPRINSSIMANVTKAFVGDTTALIDPYVEVSFFGQVGRTSTQKSSADPVWNEQVVFKEMFPPLCQRLKIRVLDEGSMNDVAIGTHYIDLHTIS-NDTDGDNGFLPTFGPAWINLYGSLRNST---LVDDSQELNEGVGEGVSYRGRLYIELSVEILSGGAAESKSLLSKFSPKDAKGGKTGTGAGGEEEKSKMIGPEVIPVEPPQKMRDEDMETFLLFGCVFEASMIDRKIGD--RPVTLEFTIGNFGNLIDGAAPPPSKKKLEDVSVTAPLLDTTATMPCKSTTTPERPIFGDAQRHYMHLPIAAQKPCVYVYSSWEDRAYRLHHANMLDTIALMFEEGVAKVTELDKMLSPEAWSLMHHV--LREFRRDAKEFIAFAEKKVKG-------SNLTLLDKKRLTMCKQELESM-TEMAGGLLEPKRRSLTVKEMLLEAQKIKKKLRFLVEEPQHTLPDVFVCLVSNNKRVAYARIPARDLLFSESPEQRGRDCGKIKTLFLK----PPVKRAPGWTVQAKLDVFLWLGTCAESSRMLDNLPSGFELVSTSFEDRTGAPPEYLLYTGKTHMFELRAHMYQARGLIAADNTGLSDPFAWVSFLSHSQCTGIIKQTLTPTWNQVIKMTNMSLYGGLYDIAQEPPLIVIEVYD-DDAVGSEYLGSTVAVPVVKLSEEQYSPPQLQYSPLFCGSLSGGDILGAFELIQSGEHS-------LPVLD---------------EPDGVVIPVPSYIRPVLCKYRIEVLFWGLRELKKVQLLS----------------VDRPQVFIKCAGSGVNSSVIQSYKKNPNFTIIVDAFDVELPEDEHLLPPLTLTVVDWRAFGRSTLVGSHVINNLA 1083          

Query: 4232 NPFQPSTKELFLKEEPDNLRMESEYVTDNSWIER-----IMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGK-KLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            NPF        L E    +R   + V   S IE+     + +Y  ELE   +FG F D  K+F L+RGK  E+D +    +RF G FKG  C+Y +   D E  +   +                                      ++ + +     V+ ++RVYI+ A NLHP+D +GK+DPYI++KLG  E++DR+NYIPK LNPVFG+  E + TFP+ES L + IYD+D +  DDLIGET IDLENR+ S H+ +C +   Y   GY  W+D   P  +L  LC+E+ +  P +     R+ I ++ F  +T+  D+D   ++S E LAL+VLH W E+  G  KLVPE+IETR LY+ +KPGI QG L+MWVD++P     P  P+DI+PRK  GYELR  +  TE V L + NF T +++ DI+VK W+K  + D Q+TDVHY SL+G+G FNWRFV+ F YL AE  +V  ++ S+Y +D+ E K P  L MQV D   + SD  +G  +  L  FP+ AK  ++C    L+E     ++F+ K+ +GWWP I   +               VE E  LVTAEEAE NPVG  R EP PLE P RPD SF  F+NP+    + I    K  +I   V+ +  L + L  Y  PG++S  IV
Sbjct: 1178 NPFP------LLFENTSGMRDRKKEVNYKSVIEQPRLATLQVYDKELE--AEFGPFDDWVKTFELFRGKANEEDGSAY--ERFVGKFKGRFCLYKLPEADGEAEEGYVDSGQ----------------------------------FKINQGIPPNTAVNVLIRVYIVAAFNLHPADPDGKADPYIVLKLGKTEIKDRDNYIPKQLNPVFGRSFEFQATFPKESLLTILIYDYDLVGGDDLIGETQIDLENRFYSRHRATCSLPTEYAIEGYNAWRDCMKPVDLLIKLCKENRLDNPQFS--PGRITIGNKVFMGKTVFPDED-QMVESYEHLALKVLHRWSEMPNGGCKLVPEHIETRALYLKDKPGIDQGHLQMWVDIFPLDMPHPGPPVDISPRKPKGYELRIIIWNTEDVILEDTNFITGQQSSDIYVKGWLKGLEDDGQETDVHYNSLTGEGNFNWRFVFPFSYLPAEKVVVVQKRESIYSLDKTEQKMPAVLVMQVWDFERLSSDDFLGSVELDLHGFPRGAKSAKACKMEMLTELTENISIFQQKRSKGWWPFIKAGELTGK-----------VEAEFHLVTAEEAEKNPVGRARKEPEPLEKPNRPDTSFSWFMNPFKCFFHLIWGNYKKYIIAGLVLLILTLFLVLLFYTLPGALSTKIV 1788          

Query:  758 QISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPD-ADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLM--IAIKTSYQP------------------------------------------------DSSKIGVDV--------RPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAK---------VASEKEP-----------TPENQYVHSMTQSRFAY--TYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYN---RECFSGK-----MPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTI 4039
            Q++V ++EA+ L G NINP   V  G +K++T  +  TN PFYNE F F+   ++  + + +I+I  + K   V+A   F    +G F ID  +VY    H F++KWAPL DPK   SG KGYVK  +SV+  GD       A    +N +IE NLL+P  + +  R   +  + IY+AE LP MN+  +  I      + K   D YV+V+FAG  G T V +   +P+WN+QI F E+FPP   R++I + D+  + D  ++T F+DL +I    +    GF PT+GP+W+NLYG+P+  T   +    +  N+ L++G+ YRGR++  ++++  + P                                                +S  +G +V           +P+     G+++ +LLF   +E T+I+  +G   KP+TFE+SIG  G   +   K         +A +++P            P N    S+T  R      YD  +  IP   +KPC+F+ +  EDH  R    N + K+   L   I +   L+   K ++A+  L   ++    S ++  S ++  R   ++  LD     LI+ ++  +  +   +   + R+ V +++ +   + K L     +PQ  LPD+F++M+    RVAYARI A  ++ S +  EKG  CG +  VY+K     + +      I A+L++Y+WLG+ +  +     LP  +     +  SG      MPP  +   D   FQLR +++ AR +I +DD+GLSDPFA+++ S     + +  +T SP W E L  D ++   + D  +  PP V++ I+D++     + LGR F +P++    + Y   +LQ++ I +G   AGEILAA +L+E+D  +       LP   D KK        +Y E +E    IPE +RP L  +R E+L WG+R L+R+                 +F V +P++ ++ AG  IES++I  + + PNF D +   D+ LP      PP+ I       FG   +VG   + NLV +   DQ +   E ++    +   KS  L    N   G L           IN L           VT+P+   ++K + +  +  E E  DWW++YYA++ +L    I
Sbjct:  224 QVNVNVIEAQKLVGVNINPAVYVTVGDEKKHTATQKSTNCPFYNENFMFEFQETQDVLFDKVIEISVVHK--KVLA---FLMTHIGSFKIDISTVYQQPDHRFYQKWAPLTDPKDTRSGIKGYVKCTVSVVMKGDPMGMASLAPAGSQNDDIEKNLLLPKRMPSE-RPWAKFILKIYRAEGLPSMNSGFMGKIMR----DKKVFLDPYVQVTFAGQQGETSVDSNTNAPEWNEQISFIEQFPPLARRIKIQILDDANIGDVAVATHFLDLLQI---SNPNRNGFNPTFGPAWVNLYGSPQNSTLRDI---HRDLNEGLSDGIFYRGRILLSLSVEVYFSPTAVVTESKAIANVKSTISRLNLKRRSRKSKEKKTGRKEGMQSPSGPAEESEDVGAEVPAAVTVEVEEVHPLPENFTGEKDEFLLFASFFEVTMIDPSIG--SKPVTFELSIGNYGKTAEVVVKSSKSGSQENLAEDRQPLLESDDELERDEPVNPRDQSITAPRRPQPTEYDRSFSCIPLFREKPCIFVWSYFEDHTFRFHNSNWLSKMADRLEYGIDEVEMLLKRSK-IKAKERLVDVVLEFFSSCKQYSSNLERKR-NPRQNNLDKCRVGLIKRNIVLLAKQTLRVRKRVTRNTVKDRLADLRNITKRLRFLAIEPQSTLPDVFLWMLSGGRRVAYARIPAPSVLFSLVEEEKGKDCGKITAVYMKTPGGPVGE------IFAKLEVYMWLGITKYAKNCVTSLPAEFRPIYEDATSGASIPRNMPPTKLAVEDSRYFQLRAHIYQARGIIAADDNGLSDPFAKVVFSTQCQVTRVMEETLSPTWCELLFYDQVLMEGSKDEYREDPPVVIINIYDYNKLGSPQALGRAFARPELKFVEEPYKKPQLQFFEITKGKSKAGEILAALELIELDYSS--FGEPALPVDVDPKK-------PQYME-EECYYIIPEGVRPVLRKYRIEVLYWGLRGLKRV----------------NLFEVERPQVRMECAGQMIESEEIQSYKLNPNFSDVVKHFDVELPELVYLHPPLTIFVMEQRAFGRLVLVGTHVVQNLVQFGPRDQEEWKDEEEEPEEKKPPKKSTPLTTVINMDLGGLP---LKHTKIPINPLN---------LVTSPIKKVIKKEEELEEEPPEKEELDWWSKYYASLAELEKQHI 1342          

Query: 4688 PVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYD----KLTDRVDIDDRSFFAETMIE-----DDDGSQIKSLEPLALEVLHHWHEIVP----GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCD-PFQLSEACAKFNLFRNKKVRGWWPLI----------------------------------YNPKXXXXXXXXXXXXXXCVELEME--LVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            P+  +VRVY++KA NL P+D NGK+DPY++VK+G +++  +E YIPK LNPVFG+  EL V+FP E+ L + ++D D +  DDLIG+T +DLENR+ S H+  CG+   Y   GY KW+D + PT IL  LC ++ +P P Y     K+ +++       F E +++     ++D +++   E  AL VLH W E+         LVPE++E R L   EKPG+ QG + MW+DM+P     P P++I PR    YELR  +  T+ V L +VN FT E + DI+VK W+K  + + Q+TDVH+ SL+G+G FNWRFV++FDYL  E  ++Y +K S++ ++E E++ P  L +QV D   I S+  +G  + RLS   +  K    C       +A  +F++FR+K+++GWWPLI                                    P+D    +  G       ++E E  LVT EEAE NPVG  R EP PL+ P RP  SF  F+NP  T  +FI  + K  +I + ++ +  L + L +Y  P  IS  IV
Sbjct: 1432 PIKVLVRVYVVKATNLAPTDPNGKADPYVVVKVGQQQMDSKERYIPKQLNPVFGEVFELTVSFPLETELTLYVFDHDLVGSDDLIGKTRVDLENRFFSRHRAGCGLALHYDKDGYNKWRDAKKPTAILLELCRKNGIPSPEYRESEIKVLNKIFRVPNEAFPEELLKKNKKTEEDYAELD--EHKALSVLHRWKEMREFCEGACPLVPEHVEVRSLLNAEKPGLPQGYVHMWIDMFPVDVPPPPPVNIKPRLPESYELRVIIWNTDDVVLDDVNPFTGEPSSDIYVKGWIKGLEDEKQETDVHFNSLTGEGNFNWRFVFHFDYLPTEKEVIYKKKESLFALEETEFRQPAVLVLQVWDYDRIGSNDFLGSIELRLSDMVRAVKTSEQCSVKMAKDKAGPRFSIFRSKRMKGWWPLIKLKSQEDIEREEREAEQEKKNKKKKKKKSSKRSQMKPEDLQFVDNSGNTFLLMGKVEAEFHLVTPEEAEKNPVGKARKEPEPLDKPNRPKTSFNWFVNPMKTFVFFIWKKYKKYIIALIILVILGLFLGLILYTMPSHISQLIV 1989          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEYFSPSTGSDNFGSDAFNF 538
            MS++V LK +       D+ ++L FR    K+  L+      F + F WP   K++++++L +  +N +++  ++LLG L I+  ++++   + +RE L D +  +TD+ +  E++Y SP  G+   G D+ +F
Sbjct:    1 MSITVLLKKIFNLPGKYDRKVELSFRGFTHKTKILQCENIAIFNEHFRWPHYGKVERDEVLSISVFNCSKMFSNRLLGKLVISLQHVVSVGQLILREPLTDAQHSLTDMYIELEVKY-SPLQGAAG-GWDSQDF 132          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKT----SYQPD-SSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVA--------------------SEKEPTPENQYVHSMTQSRF--AYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P + +  D+Q+S+T++EAR L G N++P+  V  G +K+ T +K  TN P+YNE       +S       + + R +  S       + +G ++G F +D  +VYT   H F+ KWA L DP   T+G KGY+K DI+V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT+I++N+K A+ GE K L D YV+V+FAG  G+T V   +Y P WN+QIIFTE FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT+GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RL++++      +  P+ +S   V +    PV+ T  GK E + LFG   E+T+I+  +G   KP+ FE++IG  GN +D  +K +                    S  +   E+  + S++ S        D  YFH+P+ +KKPC ++ +  +D R R++  NI++K+  +L E +     +I  EK    RR L+  +  L  S  + V+     +    +T LD +  +    +LE M  + + +  ++K++ V +K++     ++ L     +PQ+ +PDIFI+M+  N R+AYARI +++I++S +  E G  CG +  V+LK L          + +QA++++Y+WLGL +  R +  GLP G+   +   G      PP  + Y  + +FQLR +++ AR++  +D SGLSDPFAR+  +     + +  +T  P WD+ L+ DNI        ++  PP +V+EI+D D+    +F+GR F +P V +  ++Y   +    L+++ IYRG   AG++L AF+L+++    K      LP ++          D   G +    L +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:  221 MEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDEKKYTSMKESTNCPYYNE-------VSATVPTSPVPRDRAVKVSVIHSKNLLRSGTLVGSFKLDVGTVYTQPEHQFYHKWALLSDPDDITAGLKGYLKCDIAVVGKGDNIKTPHKANETDEDDIEGNLLLPDGVP-AERQWARFYVKIYRAEGLPRMNTSIMANVKKALIGENKDLVDPYVQVAFAGQKGKTSVQKSSYEPMWNEQIIFTEMFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKIANEGDK---GFLPTFGPAWVNMYGSTRNYT---LMDEHQDLNEGLGEGVSFRARLLLSLAVEILDTTNPELTSSTEVQIEGAQPVAETCTGKMEEFFLFGAFLESTMIDRKIGD--KPINFEVTIGNYGNQIDGISKPSMRKRKEGGDGVEEETELLQNSSDDEADEDGEMLSISSSPAMKPLITDRNYFHLPFFDKKPCTYIKSWWQDQRRRLYNANIMDKIADKLEEGLNDVHEMIKTEKPYPERR-LRGVLEELSSSCFRFVTLANKDQNQNGQTKLDRERLKSCMRELENMGTQAKTMRSQVKKNTVKDKLKLVQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRIAYARIPSKDILYSIVDEETGKDCGKVKCVFLK-LPGKRGFGPAGWTVQAKMEVYMWLGLSKQRRDFLCGLPCGFEEIKAVKGPGLQSFPPISLSYTKKQVFQLRAHMYQARSLFAADSSGLSDPFARVFFNTQSQCTEVLNETLCPTWDQLLVFDNIELYGEAHEMRDDPPIIVIEIYDQDTVGKADFMGRTFAKPVVKMSDERYCPPRFPPQLEYYQIYRGNSTAGDLLGAFELLQIGPAGK----SDLPQIEG-------PTDIERGPI----LPVPLGIRPVLSKYRVEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGRGVQSALIQNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSL 1202          

Query: 4340 MYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAP-IDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKF---NLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            +Y  ELE   ++  F D   +F+L RGK  +DDD     +R  G FKG++C+Y +   +    +   +                                       +++ + + +P++ +VRVY+++A +LHP+D+NGK+DPY+++KLG  +++D+ENYI K LNPVFGK  ++E TFP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   PT IL  LC+E  +  P Y     RV + +R F   T I+D++G + ++ E LAL VL HW +I   G KLVPE++ETRPL  P+KPGI+QG +EMWVDM+P     P P IDI+PRK   YELR  +  T++V L + ++FT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWRF++ FDYL AE+ IV ++K S++  DE EYK P  L +QV D+    +D  +G  +  L++FP+ AK  + C   +++E        ++F+ K+V+GWWP +   ++++ +          VE E+ L++AEEAE  P GLGR EP PLE P RPD SF+ FLNP  +I+YFI +  +W+++KI ++ + LL++ LF+Y+ PG +   I+
Sbjct: 1333 VYNKELET--EYDNFEDWLHTFNLLRGKIGDDDDTVSEEERIVGRFKGSMCVYKVPLPEDVTKEAGYDP-----------------------------------NFGMFQGIPNNDPMNVLVRVYVVRATDLHPADINGKADPYVVIKLGKTDIKDKENYISKQLNPVFGKSFDIEATFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRYYSKHRATCGISKTYAIHGYNLWRDPVKPTQILSKLCKEGKIDGPHYGP-GGRVKVTNRVFTGPTEIDDENGQKKQTDEHLALSVLQHWEDIPRVGCKLVPEHVETRPLLNPDKPGIEQGRIEMWVDMFPMDMPAPGPAIDISPRKPKRYELRVIIWNTDEVILEDDDYFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFLFPFDYLMAEEKIVISKKESMFSWDETEYKIPARLTLQVWDADHFSADDFLGAIELDLNRFPRGAKTAKQCS-IEMAEPDVDLPMVSIFKQKRVKGWWPFVARNENDEMELTGK------VEAELHLLSAEEAEKTPAGLGRNEPDPLEKPNRPDTSFIWFLNPLKSIRYFIWHTYRWLILKILILILLLLMVGLFLYSLPGYLVKKIL 1918          

Query:  758 QISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKT----SYQPD-SSKIGVDVRPCNPVSN-----------TVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVA--------------------SEKEPTPENQYVHSMTQSRF--AYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            Q+S+T++EAR L G N++P+  V  G +K+ T +K  TN P+YNE       +S       +I  + L +S          G ++G F +D  +VYT   H F+ KWA L DP   T+G KGY+K DI+V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT+I++N+K A+ GE K L D YV+V+FAG  G+T V   +Y P WN+QIIFTE FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT+GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RL++++      +  P+ +S   V +    PV+            T  GK E + LFG   E+T+I+  +G   KP+ FE++IG  GN +D  +K +                    S  +   E+  + S++ S        D  YFH+P+ +KKPC ++ +  +D R R++  NI++K+  +L     Q    +           L     N+      V+ G+    G    T  D   Q+      E M  + + +  ++K++ V +K++     ++ L     +PQ+ +PDIFI+M+  N R+AYARI +++I++S +  E G  CG +  V+LK L          + +QA++++Y+WLGL +  R +  GLP G+   +   G      PP  + Y  + +FQLR +++ AR++  +D SGLSDPFAR+  +     + +  +T  P WD+ L+ DNI        ++  PP +V+EI+D D+    +F+GR F +P V +  ++Y   +    L+++ IYRG   AG++L AF+L+++     K  +  +    DI++          G +    L +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:   39 QVSITVIEARQLVGLNMDPVVCVEVGDEKKYTSMKESTNCPYYNE-------VSATVPTSPVIHSKNLLRS----------GTLVGSFKLDVGTVYTQPEHQFYHKWALLSDPDDITAGLKGYLKCDIAVVGKGDNIKTPHKANETDEDDIEGNLLLPDGVP-AERQWARFYVKIYRAEGLPRMNTSIMANVKKALIGENKDLVDPYVQVAFAGQKGKTSVQKSSYEPMWNEQIIFTEMFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKIANEGDK---GFLPTFGPAWVNMYGSTRNYT---LMDEHQDLNEGLGEGVSFRARLLLSLAVEILDTTNPELTSSTEVQIEGAQPVAEVRTTLSYHLHLTCTGKMEEFFLFGAFLESTMIDRKIGD--KPINFEVTIGNYGNQIDGISKPSMRKRKEGGDGVEEETELLQNSSDDEADEDGEMLSISSSPAMKPLITDRNYFHLPFFDKKPCTYIKSWWQDQRRRLYNANIMDKIADKLVNETGQGEAEV-----------LHEGAGNVF-----VLEGLGRLTGDG-LTNHDCFAQQ------ENMGTQAKTMRSQVKKNTVKDKLKLVQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRIAYARIPSKDILYSIVDEETGKDCGKVKCVFLK-LPGKRGFGPAGWTVQAKMEVYMWLGLSKQRRDFLCGLPCGFEEIKAVKGPGLQSFPPISLSYTKKQVFQLRAHMYQARSLFAADSSGLSDPFARVFFNTQSQCTEVLNETLCPTWDQLLVFDNIELYGEAHEMRDDPPIIVIEIYDQDTVGKADFMGRTFAKPVVKMSDERYCPPRFPPQLEYYQIYRGNSTAGDLLGAFELLQVIGPAGKSDLPQIEGPTDIER----------GPI----LPVPLGIRPVLSKYRVEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGRGVQSALIQNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSL 989          

Query: 4316 NSWIERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAP-IDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKF---NLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
              W    ++Y  ELE   ++  F D   +F+L RGK  +DDD     +R  G FKG++C+Y +   +    +   +                                       +++ + + +P++ +VRVY+++A +LHP+D+NGK+DPY+++KLG  +++D+ENYI K LNPVFGK  ++E TFP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   PT IL  LC+E  +  P Y     RV + +R F          G + ++ E LAL VL HW +I   G KLVPE++ETRPL  P+KPGI+QG +EMWVDM+P     P P IDI+PRK   YELR  +  T++V L + ++FT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWRF++ FDYL AE+ IV ++K S++  DE EYK P  L +QV D+    +D  +G  +  L++FP+ AK  + C   +++E        ++F+ K+V+GWWP +   ++++ +          VE E+ L++AEEAE  P GLGR EP PLE P RP+ S    L+P   +   +  + +W ++ I      L+ +AL +Y  PG+IS  ++
Sbjct: 1002 QQWTTAGIVYNKELET--EYDNFEDWLHTFNLLRGKIGDDDDTVSEEERIVGRFKGSMCVYKVPLPEDVTKEAGYDP-----------------------------------NFGMFQGIPNNDPMNVLVRVYVVRATDLHPADINGKADPYVVIKLGKTDIKDKENYISKQLNPVFGKSFDIEATFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRYYSKHRATCGISKTYAIHGYNLWRDPVKPTQILSKLCKEGKIDGPHYGP-GGRVKVTNRVF---------TGQKKQTDEHLALSVLQHWEDIPRVGCKLVPEHVETRPLLNPDKPGIEQGRIEMWVDMFPMDMPAPGPAIDISPRKPKRYELRVIIWNTDEVILEDDDYFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFLFPFDYLMAEEKIVISKKESMFSWDETEYKIPARLTLQVWDADHFSADDFLGAIELDLNRFPRGAKTAKQCS-IEMAEPDVDLPMVSIFKQKRVKGWWPFVARNENDEMELTGK------VEAELHLLSAEEAEKTPAGLGRNEPDPLEKPNRPNPSLAWMLSPLRVVCVLLWRQYRWHVLGIIGSCAVLMFVALVLYTLPGAISERLI 1586          

Query:  779 EARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKT----SYQPD-SSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVA--------------------SEKEPTPENQYVHSMTQSRF--AYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELS--EIIRQTSHLISLEKNVQAR-RYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            +AR L G N++P+  V  G +K+ T +K  TN P+YNE       +S       +I  + L +S          G ++G F +D  +VYT   H F+ KWA L DP   T+G KGY+K DI+V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT+I++N+K A+ GE K L D YV+V+FAG  G+T V   +Y P WN+QIIFTE FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT+GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RL++++      +  P+ +S   V +    PV+ T  GK E + LFG   E+T+I+  +G   KP+ FE++IG  GN +D  +K +                    S  +   E+  + S++ S        D  YFH+P+ +KKPC ++ +  +D R R++  NI++K+  +LS   + +Q       ++  Q     L     N+      V+ G+    G    T  D   Q+      E M  + + +  ++K++ V +K++     ++ L     +PQ+ +PDIFI+M+  N R+AYARI +++I++S +  E G  CG +  V+LK L          + +QA++++Y+WLGL +  R +  GLP G+   +   G      PP  + Y  + +FQLR +++ AR++  +D SGLSDPFAR+  +     + +  +T  P WD+ L+ DNI        ++  PP +V+EI+D D+    +F+GR F +P V +  ++Y   +    L+++ IYRG   AG++L AF+L+++     K  +  +    DI++          G +    L +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:    4 KARQLVGLNMDPVVCVEVGDEKKYTSMKESTNCPYYNE-------VSATVPTSPVIHSKNLLRS----------GTLVGSFKLDVGTVYTQPEHQFYHKWALLSDPDDITAGLKGYLKCDIAVVGKGDNIKTPHKANETDEDDIEGNLLLPDGVP-AERQWARFYVKIYRAEGLPRMNTSIMANVKKALIGENKDLVDPYVQVAFAGQKGKTSVQKSSYEPMWNEQIIFTEMFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKIANEGDK---GFLPTFGPAWVNMYGSTRNYT---LMDEHQDLNEGLGEGVSFRARLLLSLAVEILDTTNPELTSSTEVQIEGAQPVAETCTGKMEEFFLFGAFLESTMIDRKIGD--KPINFEVTIGNYGNQIDGISKPSMRKRKEGGDGVEEETELLQNSSDDEADEDGEMLSISSSPAMKPLITDRNYFHLPFFDKKPCTYIKSWWQDQRRRLYNANIMDKIADKLSICYLGQQGPEPEWADETGQGEAEVLHEGAGNVF-----VLEGLGRLTGDG-LTNHDCFAQQ------ENMGTQAKTMRSQVKKNTVKDKLKLVQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRIAYARIPSKDILYSIVDEETGKDCGKVKCVFLK-LPGKRGFGPAGWTVQAKMEVYMWLGLSKQRRDFLCGLPCGFEEIKAVKGPGLQSFPPISLSYTKKQVFQLRAHMYQARSLFAADSSGLSDPFARVFFNTQSQCTEVLNETLCPTWDQLLVFDNIELYGEAHEMRDDPPIIVIEIYDQDTVGKADFMGRTFAKPVVKMSDERYCPPRFPPQLEYYQIYRGNSTAGDLLGAFELLQVIGPAGKSDLPQIEGPTDIER----------GPI----LPVPLGIRPVLSKYRVEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGRGVQSALIQNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSL 950          

Query: 4340 MYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAP-IDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKF---NLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            +Y  ELE   ++  F D   +F+L RGK  +DDD     +R  G FKG++C+Y +   +    +   +                                       +++ + + +P++ +VRVY+++A +LHP+D+NGK+DPY+++KLG  +++D+ENYI K LNPVFGK  ++E TFP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   PT IL  LC+E  +  P Y                        G + ++ E LAL VL HW +I   G KLVPE++ETRPL  P+KPGI+QG +EMWVDM+P     P P IDI+PRK   YELR  +  T++V L + ++FT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWRF++ FDYL AE+ IV ++K S++  DE EYK P  L +QV D+    +D  +G  +  L++FP+ AK  + C   +++E        ++F+ K+V+GWWP +   ++++ +          VE E+ L++AEEAE  P GLGR EP PLE P RP+ S    L+P   +   +  + +W ++ I      L+ +AL +Y  PG+IS  ++
Sbjct: 1028 VYNKELET--EYDNFEDWLHTFNLLRGKIGDDDDTVSEEERIVGRFKGSMCVYKVPLPEDVTKEAGYDP-----------------------------------NFGMFQGIPNNDPMNVLVRVYVVRATDLHPADINGKADPYVVIKLGKTDIKDKENYISKQLNPVFGKSFDIEATFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRYYSKHRATCGISKTYAIHGYNLWRDPVKPTQILSKLCKEGKIDGPHYGP----------------------GQKKQTDEHLALSVLQHWEDIPRVGCKLVPEHVETRPLLNPDKPGIEQGRIEMWVDMFPMDMPAPGPAIDISPRKPKRYELRVIIWNTDEVILEDDDYFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFLFPFDYLMAEEKIVISKKESMFSWDETEYKIPARLTLQVWDADHFSADDFLGAIELDLNRFPRGAKTAKQCS-IEMAEPDVDLPMVSIFKQKRVKGWWPFVARNENDEMELTGK------VEAELHLLSAEEAEKTPAGLGRNEPDPLEKPNRPNPSLAWMLSPLRVVCVLLWRQYRWHVLGIIGSCAVLMFVALVLYTLPGAISERLI 1592          

Query:  755 FQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAI-------------------------------KTSYQPDSSKIGVDVRPCNPVSNTVA----------------GKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQ----------------------YVHSMTQSRFAYTYDNKYFH-IPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFS------GKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVK--DIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTA-----PVP------------GTVEKVKPVLPQTEEMESA----DWWTRYYATIGDL 4024
             QI++TI EAR L G NI+P+  +  G  K+ T +K  TN+PFYNE+F FD    + ++ + II++       +V+  ++    ++G F +D  +VY   GH F  KWA L DP    +G KGY+K DISV   GD  +      + E   IE NLLIP    +  R      V IY+AE LP MN++I++N+  A  G+ K L D YV V FAG  GRT        P W++QI+F E FPP   R++I V D   + D  ++T FIDL+KI       ++GFLPT+GP+WINLYG+PR    T L++  Q  N+   EGV++RGR++I I                               K S +    K   D +P + V  T +                 K E +LLFG I+E TLI+  +G  G  ++FE S+G  GN+LD  +   ++K+ +PE++                      ++   T  +   T  N+ +H +P+  +KPC+++ +   D   R++  N+++K+   L + + Q   L+ +  ++     ++  +   I      +S  +        T LD K   L R +LE M    + +  + K+ ++ +  RE  +L+  ++  + +PQ+ +PD+FI+++  N RVAYARI AR+I++S++A E+G  CG + T++ K       K    +N+QA++ +YLWLG  +        LP GY  E  S      G  PP  + Y  + MFQLR +++ AR +I +D SGLSDPFA++    H   + I +QT SP W++ L+ +N++       +   PPN+V+E++D D+ +  E++G     P V +    Y+ AKL +  ++ G L+ GE+LAAF+L+++     +  V+ LP ++  D  ++                  +P  IRP LS +R E+L WGVR+L++++++                 V++P++ I+ AG  ++S  I  +   PNF     + ++ LP +    PP++I   +   FG   +VG   I  L  +      +    I           S +         G  +  + + D S   ++   +   P P  TA     P P            G++ +      +T   ESA    DWW++YYA++  L
Sbjct:   19 LQIAITITEARQLIGENIDPVVIIEIGDDKKQTTVKEGTNAPFYNEYFVFDFIGPQEQLFDKIIRL-------SVMHNKLLGSILIGSFRVDLGTVYNEPGHQFCDKWALLTDPSDIRTGVKGYLKCDISVAGKGDTVQSSQKISDAEE-QIEKNLLIPKGFPSE-RPWARFYVRIYRAEGLPKMNSSIMANVTKAFIGDSKDLVDPYVVVMFAGQMGRTTAQKNCADPLWHEQIVFKEMFPPLCRRVKIQVWDEGSMNDVALATHFIDLKKIS-DEQDGDKGFLPTFGPAWINLYGSPRN---TTLMEDHQELNEGHGEGVSFRGRILIEIAVEILSGGAHESKFSKAIKDMKLPLKDSKSSKGSGKEKGEKGSEDAKPTSAVDKTNSIQVEVEPFDVPPEFQEEKSEDFLLFGSIFEATLIDRKIGDKG--ISFECSVGNYGNVLDGVSHSGTKKK-SPEHEDGEGAPLLQPEEGEAAPEVSLSFISVTTPEKPLITDGNRNYHYLPFYERKPCIYVKSTWGDQTFRLYSSNMLQKMADHLEDGLEQVKELVKI-SDLAPEEKMRDVLTEFINQSRAFISTAEKRSKMTNTTALDKKRVTLCRQELEAMSANAKAIVQQKKKMSLSDMTREMQSLIDNIKFLVDEPQHTVPDVFIWLLSNNKRVAYARIPARDILYSTLAEERGHHCGKIKTLFFKLPG----KRPPGWNVQAKVDVYLWLGSSKYSHFIFENLPGGYEVETHSASSGHHGSPPPGNLVYKSQHMFQLRAHMYQARGLIAADTSGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQMLLFNNLVIYGELKDIAEDPPNIVIEVYDDDALSKSEYIGSTVASPTVILANQTYSPAKLTYHPLFCGNLSGGELLAAFELLQV----PESGVQSLPPIETPDAAQIYP----------------VPSNIRPVLSKYRVEVLFWGVRELKKVQLLS----------------VDRPQVLIECAGKGVKSCVIQSYKSNPNFNVIGDWFEVELPENEVLHPPLSICVVDWRAFGRSTLVGTHTINCLKQFLYKPHREQTSAIVGLVAQSPPYDSPD--------PGEQDHIYVDIDPSLRKDMPQSRPHSPAPSPTATLAPSPTPAAGPASDPAASKGSLRRSTKKKKRTIADESAENVIDWWSKYYASVEKL 1142          

Query: 4652 TLRLYKNLRDINPVD-----------------FVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACA-----KFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVT 6217
            +  +YKN+ D NP D                  ++RVYI+   NL P+D +GKSDPYI+++LG  E++DR+NYIPK LNPVFG+  E++ TFP++S L + IYD D +  DDLIGET IDLENR+ S H+ +CG+   Y   GY  W+D   PT IL  LC+++ +  P       ++ I  + F  +T+   DD  Q++S E LAL+ LH W +I   G  LVPE+IETRPLY  +KPGI+QG ++MWVDM+P    +P  P+DI+PRK  GYELR  +  TE V L + N FT +K+ DI+VK W+K  + D Q+TDVHY SL+G+G FNWRFV+ F YL AE  +V +++ +++ +++ E K P  L +QV D   + SD  +G  +  L+ F + AK  + CD   LS A       K ++F+ K++RGWWP + + +               VE E  LVT EEAE NPVG  R EP PLE P RP+ SF  F+NP+  + + I    K  +I   V+ +  L + LF Y  PG+ISN I++
Sbjct: 1224 SFSIYKNVDDTNPKDGGQLRILQGIPPNHTVKVLIRVYIVAGFNLSPADPDGKSDPYIVLRLGKTEIKDRDNYIPKQLNPVFGRSFEMQATFPKDSILSIVIYDHDMIGTDDLIGETKIDLENRFFSRHRATCGLQSQYEIEGYNAWRDSTKPTEILAKLCKDNKLDGPYLR--PGQIQIGGKIFTGQTIFNQDD-EQVESYEHLALKALHSWSDIPDIGCNLVPEHIETRPLYHKDKPGIEQGRIQMWVDMFPTDLPLPGPPVDISPRKPKGYELRIIIWNTEDVILEDENIFTGQKSSDIYVKGWLKGIEDDSQETDVHYNSLTGEGNFNWRFVFPFSYLPAEKLMVVSKRENIFSLEKTERKIPTVLLLQVWDFDRLSSDDFLGSMELNLNAFHRGAKTAKGCD---LSMAATPKDENKISIFQQKRIRGWWPFVKSGELTGK-----------VEAEFHLVTTEEAEKNPVGRARKEPEPLEKPNRPNTSFNWFVNPFKCLYHLIWRNYKKYIIIGLVLLIITLFLVLFFYTLPGAISNRILS 1753          

Query:  755 FQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAI-------------------------------KTSYQPDSSKIGVDVRPCNPVSNT------------------VAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEM-SIGITGNLLDDYAKVASEKEPTPENQ----------------------YVHSMTQSRFAYTYDNKYFH-IPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFS------GKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVK--DIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAP------VPGTVEKVKPVLPQTEEMESA----DWWTRYYATIGDL 4024
             QI++TI EAR L G NI+P+  +  G  K+ T +K  TN+PFYNE+F FD    + ++ + II++       +V+  ++    ++G F +D  +VY   GH F  KWA L DP    +G KGY+K DISV   GD  +      + E   IE NLLIP    +  R      V IY+AE LP MN++I++N+  A  G+ K L D YV V FAG  GRT        P W++QI+F E FPP   R++I V D   + D  ++T FIDL+KI       ++GFLPT+GP+WINLYG+PR    T L++  Q  N+   EGV++RGR++I I                               K S +    K   D +P + V  T                     K E +LLFG I+E TLI+  +G  G  ++FE+ S G  GN+LD  +   ++K+ +PE++                      ++   T  +   T  N+ +H +P+  +KPC+++ +   D   R++  N+++K+   L + + Q   L+ +  ++     ++  +   I      +S  +        T LD K   L R          Q L +  KR N              L   +A PQ+ +PD+FI+++  N RVAYARI AR+I++S++A E+G  CG + T++ K       K    +N+QA++ +YLWLG  +        LP GY  E  S      G  PP  + Y  + MFQLR +++ AR +I +D SGLSDPFA++    H   + I +QT SP W++ L+ +N++       +   PPN+V+E++D D+ +  E++G     P V +    Y+ AKL +  ++ G L+ GE+LAAF+L++         V+ LP ++  D  ++                  +P  IRP LS +R E+L WGVR+L++++++                 V++P++ I+ AG  ++S  I  +   PNF     + ++ LP +    PP++I   +   FG   +VG   I  L  +         RE                      T  I+        G       DM + +P+    +P      V G++ +      +T   ESA    DWW++YYA++  L
Sbjct:   39 LQIAITITEARQLIGENIDPVVIIEIGDDKKQTTVKEGTNAPFYNEYFVFDFIGPQEQLFDKIIRL-------SVMHNKLLGSILIGSFRVDLGTVYNEPGHQFCDKWALLTDPSDIRTGVKGYLKCDISVAGKGDTVQSSQKISDAEE-QIEKNLLIPKGFPSE-RPWARFYVRIYRAEGLPKMNSSIMANVTKAFIGDSKDLVDPYVVVMFAGQMGRTTAQKNCADPLWHEQIVFKEMFPPLCRRVKIQVWDEGSMNDVALATHFIDLKKIS-DEQDGDKGFLPTFGPAWINLYGSPRN---TTLMEDHQELNEGHGEGVSFRGRILIEIAVEILSGGAHESKFSKAIKDMKLPLKDSKSSKGSGKEKGEKGSEDAKPTSAVDKTNSIQVEVEPFDVPPEVSFSVEKSEDFLLFGSIFEATLIDRKIGDKG--ISFEIISTGNYGNVLDGVSHSGTKKK-SPEHEDGEGAPLLQPEEGEAAPEVSLSFISVTTPEKPLITDGNRNYHYLPFYERKPCIYVKSTWGDQTFRLYSSNMLQKMADHLEDGLEQVKELVKIS-DLAPEEKMRDVLTEFINQSRAFISTAEKRSKMTNTTALDKKRVTLCR----------QELVVGPKRYN--------------LSHFLAQPQHTVPDVFIWLLSNNKRVAYARIPARDILYSTLAEERGHHCGKIKTLFFKLPG----KRPPGWNVQAKVDVYLWLGSSKYSHFIFENLPGGYEVETHSASSGHHGSPPPGNLVYKSQHMFQLRAHMYQARGLIAADTSGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQMLLFNNLVIYGELKDIAEDPPNIVIEVYDDDALSKSEYIGSTVASPTVILANQTYSPAKLTYHPLFCGNLSGGELLAAFELLQSG-------VQSLPPIETPDAAQIYP----------------VPSNIRPVLSKYRVEVLFWGVRELKKVQLLS----------------VDRPQVLIECAGKGVKSCVIQSYKSNPNFNVIGDWFEVELPENEVLHPPLSICVVDWRAFGRSTLVGTHTINCLKQFL----YKPHRE---------------------QTSAIV--------GLVAQSPKDMPQSRPHSPAPSPTATLALVRGSLRRSTKKKKRTIADESAENVIDWWSKYYASVEKL 1102          

Query: 4652 TLRLYKNLRDINPVD-----------------FVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACA-----KFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVT 6217
            +  +YKN+ D NP D                  ++RVYI+   NL P+D +GKSDPYI+++LG  E++DR+NYIPK LNPVFG+  E++ TFP++S L + IYD D +  DDLIGET IDLENR+ S H+ +CG+   Y   GY  W+D   PT IL  LC+++ +  P       ++ I  + F  +T+   DD  Q++S E LAL+ LH W +I   G  LVPE+IETRPLY  +KPGI+QG ++MWVDM+P    +P  P+DI+PRK  GYELR  +  TE V L + N FT +K+ DI+VK W+K  + D Q+TDVHY SL+G+G FNWRFV+ F YL AE  +V +++ +++ +++ E K P  L +QV D   + SD  +G  +  L+ F + AK  + CD   LS A       K ++F+ K++RGWWP + + +               VE E  LVT EEAE NPVG  R EP PLE P RP+ SF  F+NP+  + + I    K  +I   V+ +  L + LF Y  PG+ISN I++
Sbjct: 1183 SFSIYKNVDDTNPKDGGQLRILQGIPPNHTVKVLIRVYIVAGFNLSPADPDGKSDPYIVLRLGKTEIKDRDNYIPKQLNPVFGRSFEMQATFPKDSILSIVIYDHDMIGTDDLIGETKIDLENRFFSRHRATCGLQSQYEIEGYNAWRDSTKPTEILAKLCKDNKLDGPYLR--PGQIQIGGKIFTGQTIFNQDD-EQVESYEHLALKALHSWSDIPDIGCNLVPEHIETRPLYHKDKPGIEQGRIQMWVDMFPTDLPLPGPPVDISPRKPKGYELRIIIWNTEDVILEDENIFTGQKSSDIYVKGWLKGIEDDSQETDVHYNSLTGEGNFNWRFVFPFSYLPAEKLMVVSKRENIFSLEKTERKIPTVLLLQVWDFDRLSSDDFLGSMELNLNAFHRGAKTAKGCD---LSMAATPKDENKISIFQQKRIRGWWPFVKSGELTGK-----------VEAEFHLVTTEEAEKNPVGRARKEPEPLEKPNRPNTSFNWFVNPFKCLYHLIWRNYKKYIIIGLVLLIITLFLVLFFYTLPGAISNRILS 1712          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNG-KPLTFEMSIGITGNLLDDYAKVAS---EKEPTPENQY-------------------VHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P + +  D+Q+S+T++EAR L G N++P+  V  G  K+ T +K  TN P+YNE+F FD  +S   M + IIKI  +   N      + +G ++G F +D  +VY+   H F  KWA L DP   ++G KGYVK D++V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT++++N+K A  GE K L D YV+V FAG  G+T V   +Y P WN+Q++FT+ FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RLM+ +      TS    +S   V V    PVS +  G+ E + LFG   E ++I+    KNG KP+TFE++IG  GN +D  ++       KEP  E +                    V S    R   T D  YFH+PY  +KPC+++ +   D R R++  NI++ +  +L E +     +I  EK+   RR L+  +  L     + +S     +G + +T LD +  +    +LE M  + ++L  ++KR  V +K+R C   ++ L     +PQ+ +PD+FI+M+  N R+AYAR+ +++++ S +  E G  C  + T++LK L       +  + +QA+L++YLWLGL +  + +  GLP G+   +   G      PP  + Y  +  FQLR +++ AR++  +D SGLSDPFAR+        + +  +T  P WD+ L+ DN+        L+  PP +V+EI+D DS    +F+GR F +P V +  + Y   +    L+++ IYRG+  AG++LAAF+L+++    K           D+  +   ++ +R   M      +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:  243 MEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKN-----LLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVP-PERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRNYT---LLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPELTSSTEVQVEQATPVSESCTGRMEEFFLFGAFLEASMIDR---KNGDKPITFEVTIGNYGNEVDGMSRPLRPRPRKEPGDEEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQIT-DRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERR-LRGVLEELSCGCHRFLSLSDKDQGRSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRSCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFSIVEEELGKDCAKVKTLFLK-LPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGSATAGDLLAAFELLQIGPSGK----------ADLPPINGPVDMDRGPIMP-----VPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSL 1225          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFN-----LFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            I+ + +YP ELE+  +F  F D   +F+L RGK  +D+D     +R  G FKG++C+Y +   +    +   +                                    T  +++ +   +P++ +VR+Y+++A +LHP+D+NGK+DPYI +KLG  ++RD+ENYI K LNPVFGK  ++E +FP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   P+ IL  LC+E  V  P +     RV + +R F   + IED++G +  + E +AL  L HW +I   G +LVPE++ETRPL  P+KPGI+QG LE+WVDM+P     P  P+DI+PRK   YELR  V  T++V L + +FFT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWR+++ FDYL AE+ IV ++K S++  DE EYK P  L +Q+ D+    +D  +G  +  L++FP+ AK  + C    +  A  + +     +F+ K+V+GWWPL+   ++++ +          VE E+ L+TAEEAE NPVGL R EP PLE P RPD SF+ FLNP  + +YF+ +  +W+L+K  ++F+ LL+ ALF+Y+ PG ++  I+
Sbjct: 1405 IDELKVYPKELES--EFDSFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDP-----------------------------------TYGMFQGIPSNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGP-HGRVRVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQC---TMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK------VEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKFLLLFLLLLLFALFLYSLPGYLAKKIL 1995          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIY-FGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEY 487
            M+L V+LK +      GD+  K+ FR     S  L+    +  F + F WP+A  +D+N++L ++ +N ++V  +KL+G   +    ++ E  + V + L+D+   I    ++ E+ Y
Sbjct:    1 MALIVHLKTVSELRGKGDRIAKVTFRGQSFYSRVLENCEGVADFDETFRWPVASSIDRNEVLEIQIFNYSKVFSNKLIGTFCMVLQKVVEENRVEVTDTLMDDSNAIIKTSLSMEVRY 118          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNG-KPLTFEMSIGITGNLLDDYAKVAS---EKEPTPENQY-------------------VHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P + +  D+Q+S+T++EAR L G N++P+  V  G  K+ T +K  TN P+YNE+F FD  +S   M + IIKI  +   N      + +G ++G F +D  +VY+   H F  KWA L DP   ++G KGYVK D++V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT++++N+K A  GE K L D YV+V FAG  G+T V   +Y P WN+Q++FT+ FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RLM+ +      TS    +S   V V    PVS +  G+ E + LFG   E ++I+    KNG KP+TFE++IG  GN +D  ++       KEP  E +                    V S    R   T D  YFH+PY  +KPC+++ +   D R R++  NI++ +  +L E +     +I  EK+   RR L+  +  L     + +S     +G + +T LD +  +    +LE M  + ++L  ++KR  V +K+R C   ++ L     +PQ+ +PD+FI+M+  N R+AYAR+ +++++ S +  E G  C  + T++LK L       +  + +QA+L++YLWLGL +  + +  GLP G+   +   G      PP  + Y  +  FQLR +++ AR++  +D SGLSDPFAR+        + +  +T  P WD+ L+ DN+        L+  PP +V+EI+D DS    +F+GR F +P V +  + Y   +    L+++ IYRG+  AG++LAAF+L+++    K           D+  +   ++ +R   M      +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:  258 MEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKN-----LLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVP-PERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRNYT---LLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPELTSSTEVQVEQATPVSESCTGRMEEFFLFGAFLEASMIDR---KNGDKPITFEVTIGNYGNEVDGMSRPLRPRPRKEPGDEEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQIT-DRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERR-LRGVLEELSCGCHRFLSLSDKDQGRSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRSCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFSIVEEELGKDCAKVKTLFLK-LPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGSATAGDLLAAFELLQIGPSGK----------ADLPPINGPVDMDRGPIMP-----VPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSL 1240          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFN-----LFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            I+ + +YP ELE+  +F  F D   +F+L RGK  +D+D     +R  G FKG++C+Y +   +    +   +                                    T  +++ +   +P++ +VR+Y+++A +LHP+D+NGK+DPYI +KLG  ++RD+ENYI K LNPVFGK  ++E +FP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   P+ IL  LC+E  V  P +     RV + +R F   + IED++G +  + E +AL  L HW +I   G +LVPE++ETRPL  P+KPGI+QG LE+WVDM+P     P  P+DI+PRK   YELR  V  T++V L + +FFT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWR+++ FDYL AE+ IV ++K S++  DE EYK P  L +Q+ D+    +D  +G  +  L++FP+ AK  + C    +  A  + +     +F+ K+V+GWWPL+   ++++ +          VE E+ L+TAEEAE NPVGL R EP PLE P RPD +F+ FLNP  +IKY I  R KW++IKI +  + LL++ALF+Y+ PG     +V K+ G
Sbjct: 1400 IDELKVYPKELES--EFDSFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDP-----------------------------------TYGMFQGIPSNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGP-HGRVRVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQC---TMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK------VEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKIVLALLGLLMLALFLYSLPG----YMVKKLLG 1991          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIY-FGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEY 487
            M+L V+LK +      GD+  K+ FR     S  L+    +  F + F WP+A  +D+N++L ++ +N ++V  +KL+G   +    ++ E  + V + L+D+   I    ++ E+ Y
Sbjct:    1 MALIVHLKTVSELRGKGDRIAKVTFRGQSFYSRVLENCEGVADFDETFRWPVASSIDRNEVLEIQIFNYSKVFSNKLIGTFCMVLQKVVEENRVEVTDTLMDDSNAIIKTSLSMEVRY 118          

Query:  710 KLPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPK-RPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAI--------------------------------------------------KTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTP-------------ENQYVHSMTQSRFAYTYDNK---------YFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRS-NVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNREC---FSG-KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVK--DIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDE---------RSVKSLNLFNAGNDTEG------------ILNEGFENEDGSAIN--ELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEM---------ESA----DWWTRYYATI 4015
            KL   I    +K +++QI+VTI EAR L G NI+P+  +  G  K+ + +K  TNSPFYNE+F FD    ++ + + IIKI       +V+  ++    ++G F +D  +VY   GH F  KWA L DP    +G KGY+K DISV   GD  K  P   D EE   IE NLLIP    +  R      V +Y+AE LP MN++I++N+  A  G+ K L D +VEVSFAG TGRT V      P W++Q++F E FPP   R++I V D   + D  ++T FIDL+KI       ++GFLPT+GP+WINLYG+PR  +   L+   Q  N+   EGV++RGR+++ I                                                  +T+ + +S+++ V+     P    +  K E +LLFG  +E T+I+  +G   KP++FE+S+G  GNL+D  +   S+K+ T              E         S  + T+  K         Y ++P+  KKPC+  I+   D   R+   N++EK+   L E I +   L+ + +     + +KT++ + I      +S  +    T  +T LD K   L   +L+ M  + + +  + K+  ++ E +RE    V+ +   + +PQ+ +PD+FI+M+  N RVAYARI A+++++S +  + G  CG + T +LK       K    + +QA++ IYLWLG  R        LP GY  E     SG   PP  + Y  + +FQLR +++ AR +I +D +GLSDPFA++        + I +QT SP W++ L+ + ++ +     L  SPP+VVVE++D D+    E+LG     P V +    Y   KL +  I+ G L+ G++LA F+L+++        ++GLP     DI ++                  +P  IRP LS +R E+L WGVR++++++++                 V++P++ I+  G  ++S  I  +   PNF       ++ LP +    PP++I   +   FG   +VG   I N +  + C   + F    +T  D           + +S NL ++  D               +L +  + +  + ++  + + M E +  P    P P       P  P              ESA    DWW++YYA++
Sbjct:   67 KLLTKIHDGEIKSQNYQITVTITEARQLVGENIDPVVTIEIGDDKKQSTVKEGTNSPFYNEYFVFDFIGPQVHLFDKIIKI-------SVLHHKLIGSILIGSFRVDVGTVYNQPGHQFCDKWALLTDPGDIRTGTKGYLKCDISVTGKGDILKTNPKTSDAEEQ--IEKNLLIPQGFPSE-RPWARFYVRLYRAEGLPKMNSSIMANVTKAFVGDSKDLVDPFVEVSFAGQTGRTSVQKNCADPVWHEQVVFKEMFPPLCRRVKIQVWDEGSMNDVALATHFIDLKKIS-NEQDGDKGFLPTFGPAWINLYGSPRNHS---LMDDYQELNEGFGEGVSFRGRILVEIAVEILSGGAQESKFSKALKELKLSSKDKDSKSSKGSSKDKADKADDSKAQQTTDKTNSTEVEVESFAVPP--EIIPEKYEDFLLFGAFFEATMIDRKIGD--KPISFEVSVGNFGNLIDGGSHHGSKKKSTELTEEDVLPLLHEGEKDVAQDSAISMASTTHPEKPLVTDGNRNYNYLPFGAKKPCVSFISSWGDQTFRLHWSNMLEKMADLLEEGIEEVRELVKVSQEAPEEK-MKTALRDFITQSRVFISEAEKKPKTLNQTALDKKRLTLCWQELKAMADEAEGVIRQQKKKLSLDEMIREAQNFVEKIHFLVDEPQHTIPDVFIWMLSNNKRVAYARIAAKDLLYSPIEEQMGKHCGKIKTHFLKLPG----KRPPGWTVQAKVDIYLWLGSTRYSNTILDNLPVGYEAEMPPKSSGTHHPPSALLYQAQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSQCQTTKIISQTLSPTWNQMLLFNELVLHGEEKELLESPPHVVVELYDSDAVGKPEYLGATVAAPVVTLADQDYEPPKLSYHPIFCGNLSGGDLLAVFELLQVPPS----GLQGLPPTGPPDITQIYP----------------VPSNIRPVLSKYRVEVLFWGVREMKKVQLLS----------------VDRPQVLIECGGGGVKSCVIQSYKNNPNFSVQAEAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTI-NCLKQFLCKPRETFALTSQTDGDGARPAISDSLAATESSNLLSSSQDLPADHVYVDVEPPPTMLPDSAQAQTATLVDIPDSSPMLETEHKPVAQGP-PKDGHGKDPRKPSRRSTKRRRRTIADESAENVIDWWSKYYASV 1223          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQ-IKSLEPLALEVLHHWHEIV-PGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGT-AIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACA--KFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            +  + +Y  +LE+  +F  F D  K+F L+RGK  E+D   +  DR  G FKG+ CIY                                          ++   E    LR+ + +   +PV  ++RVYI+ A NL P+D +GKSDPYI+++LG  E++DR+ YIPK LNPVFG+  E++ TFP+ES L V IYD D +  DDLIGET IDLENR+ S H+  CG+   Y   GY  W+D   PT IL  LC+++ +  P +     ++ I  + F  +T+  ++D  + ++S E LAL+VLH W +I   G +LVPE+IETRPLY  +KPG++QG L+MWVDM+P  T  +  P+DI+PRK  GYELR T+  TE V L + N FT +K+ DI+VK W+K  + D Q+TDVHY SL+G+G FNWRF++ F YL AE  +V +++ +++ +++ E KTP  L +QV D   + SD  +G  +  L+ FP+ AK  ++CD  +   A    K ++F+ K+VRGWWP   + +               VE E  LVTAEEAE NPVG  R EP PL  P RPD SF  F++P+  + + I    K  +I  F++ + ++ + LFIY  PG+IS  IV
Sbjct: 1278 LAALKIYDGDLES--EFNNFEDWVKTFELFRGKSTEEDHGLDG-DRVIGKFKGSFCIYK---------------------------------------SPEDSTSEDSGQLRIQQGIPPNHPVQVLIRVYIVAAFNLSPADPDGKSDPYIVLRLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSVLIYDHDMIGSDDLIGETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYF--RPGKIQIGKKVFSGKTVFNEEDSEEMVESYEHLALKVLHSWEDIPEAGWRLVPEHIETRPLYHKDKPGMEQGRLQMWVDMFPKDTPQLGPPVDISPRKPKGYELRVTIWNTEDVILEDENIFTGQKSSDIYVKGWIKGLEDDRQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVISKRENIFSLEKMECKTPAVLVLQVWDFERLSSDDFLGSLEMNLNSFPRAAKSAKACDLSKFENAVQENKISIFQQKRVRGWWPFAKSKELTGK-----------VEAEFHLVTAEEAEKNPVGKARKEPEPLAKPNRPDTSFSWFVSPFKCLYHLIWKNYKKYIIIAFILIILIVFLVLFIYTLPGAISRRIV 1858          

Query:  710 KLPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPK-RPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAI--------------------------------------------------KTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTP-------------ENQYVHSMTQSRFAYTYDNK---------YFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRS-NVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNREC---FSG-KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVK--DIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDE---------RSVKSLNLFNAGNDTEG------------ILNEGFENEDGSAIN--ELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEM---------ESA----DWWTRYYATI 4015
            KL   I    +K +++QI+VTI EAR L G NI+P+  +  G  K+ + +K  TNSPFYNE+F FD    ++ + + IIKI       +V+  ++    ++G F +D  +VY   GH F  KWA L DP    +G KGY+K DISV   GD  K  P   D EE   IE NLLIP    +  R      V +Y+AE LP MN++I++N+  A  G+ K L D +VEVSFAG TGRT V      P W++Q++F E FPP   R++I V D   + D  ++T FIDL+KI       ++GFLPT+GP+WINLYG+PR  +   L+   Q  N+   EGV++RGR+++ I                                                  +T+ + +S+++ V+     P    +  K E +LLFG  +E T+I+  +G   KP++FE+S+G  GNL+D  +   S+K+ T              E         S  + T+  K         Y ++P+  KKPC+  I+   D   R+   N++EK+   L E I +   L+ + +     + +KT++ + I      +S  +    T  +T LD K   L   +L+ M  + + +  + K+  ++ E +RE    V+ +   + +PQ+ +PD+FI+M+  N RVAYARI A+++++S +  + G  CG + T +LK       K    + +QA++ IYLWLG  R        LP GY  E     SG   PP  + Y  + +FQLR +++ AR +I +D +GLSDPFA++        + I +QT SP W++ L+ + ++ +     L  SPP+VVVE++D D+    E+LG     P V +    Y   KL +  I+ G L+ G++LA F+L+++        ++GLP     DI ++                  +P  IRP LS +R E+L WGVR++++++++                 V++P++ I+  G  ++S  I  +   PNF       ++ LP +    PP++I   +   FG   +VG   I N +  + C   + F    +T  D           + +S NL ++  D               +L +  + +  + ++  + + M E +  P    P P       P  P              ESA    DWW++YYA++
Sbjct:   67 KLLTKIHDGEIKSQNYQITVTITEARQLVGENIDPVVTIEIGDDKKQSTVKEGTNSPFYNEYFVFDFIGPQVHLFDKIIKI-------SVLHHKLIGSILIGSFRVDVGTVYNQPGHQFCDKWALLTDPGDIRTGTKGYLKCDISVTGKGDILKTNPKTSDAEEQ--IEKNLLIPQGFPSE-RPWARFYVRLYRAEGLPKMNSSIMANVTKAFVGDSKDLVDPFVEVSFAGQTGRTSVQKNCADPVWHEQVVFKEMFPPLCRRVKIQVWDEGSMNDVALATHFIDLKKIS-NEQDGDKGFLPTFGPAWINLYGSPRNHS---LMDDYQELNEGFGEGVSFRGRILVEIAVEILSGGAQESKFSKALKELKLSSKDKDSKSSKGSSKDKADKADDSKAQQTTDKTNSTEVEVESFAVPP--EIIPEKYEDFLLFGAFFEATMIDRKIGD--KPISFEVSVGNFGNLIDGGSHHGSKKKSTELTEEDVLPLLHEGEKDVAQDSAISMASTTHPEKPLVTDGNRNYNYLPFGAKKPCVSFISSWGDQTFRLHWSNMLEKMADLLEEGIEEVRELVKVSQEAPEEK-MKTALRDFITQSRVFISEAEKKPKTLNQTALDKKRLTLCWQELKAMADEAEGVIRQQKKKLSLDEMIREAQNFVEKIHFLVDEPQHTIPDVFIWMLSNNKRVAYARIAAKDLLYSPIEEQMGKHCGKIKTHFLKLPG----KRPPGWTVQAKVDIYLWLGSTRYSNTILDNLPVGYEAEMPPKSSGTHHPPSALLYQAQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSQCQTTKIISQTLSPTWNQMLLFNELVLHGEEKELLESPPHVVVELYDSDAVGKPEYLGATVAAPVVTLADQDYEPPKLSYHPIFCGNLSGGDLLAVFELLQVPPS----GLQGLPPTGPPDITQIYP----------------VPSNIRPVLSKYRVEVLFWGVREMKKVQLLS----------------VDRPQVLIECGGGGVKSCVIQSYKNNPNFSVQAEAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTI-NCLKQFLCKPRETFALTSQTDGDGARPAISDSLAATESSNLLSSSQDLPADHVYVDVEPPPTMLPDSAQAQTATLVDIPDSSPMLETEHKPVAQGP-PKDGHGKDPRKPSRRSTKRRRRTIADESAENVIDWWSKYYASV 1223          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQ-IKSLEPLALEVLHHWHEIV-PGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGT-AIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACA--KFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            +  + +Y  +LE+  +F  F D  K+F L+RGK  E+D   +  DR  G FKG+ CIY                                          ++   E    LR+ + +   +PV  ++RVYI+ A NL P+D +GKSDPYI+++LG  E++DR+ YIPK LNPVFG+  E++ TFP+ES L V IYD D +  DDLIGET IDLENR+ S H+  CG+   Y   GY  W+D   PT IL  LC+++ +  P +     ++ I  + F  +T+  ++D  + ++S E LAL+VLH W +I   G +LVPE+IETRPLY  +KPG++QG L+MWVDM+P  T  +  P+DI+PRK  GYELR T+  TE V L + N FT +K+ DI+VK W+K  + D Q+TDVHY SL+G+G FNWRF++ F YL AE  +V +++ +++ +++ E KTP  L +QV D   + SD  +G  +  L+ FP+ AK  ++CD  +   A    K ++F+ K+VRGWWP   + +               VE E  LVTAEEAE NPVG  R EP PL  P RPD SF  F++P+  + + I    K  +I  F++ + ++ + LFIY  PG+IS  IV
Sbjct: 1278 LAALKIYDGDLES--EFNNFEDWVKTFELFRGKSTEEDHGLDG-DRVIGKFKGSFCIYK---------------------------------------SPEDSTSEDSGQLRIQQGIPPNHPVQVLIRVYIVAAFNLSPADPDGKSDPYIVLRLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSVLIYDHDMIGSDDLIGETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYF--RPGKIQIGKKVFSGKTVFNEEDSEEMVESYEHLALKVLHSWEDIPEAGWRLVPEHIETRPLYHKDKPGMEQGRLQMWVDMFPKDTPQLGPPVDISPRKPKGYELRVTIWNTEDVILEDENIFTGQKSSDIYVKGWIKGLEDDRQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVISKRENIFSLEKMECKTPAVLVLQVWDFERLSSDDFLGSLEMNLNSFPRAAKSAKACDLSKFENAVQENKISIFQQKRVRGWWPFAKSKELTGK-----------VEAEFHLVTAEEAEKNPVGKARKEPEPLAKPNRPDTSFSWFVSPFKCLYHLIWKNYKKYIIIAFILIILIVFLVLFIYTLPGAISRRIV 1858          

Query:  743 KIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGL-SKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTS------------------------------------------YQPDS-----------SKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLD--------DYAKVASEKEPTP------------ENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKS-CRGTAKKTM-----LDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTK-KITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVD-----NFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKEVIEKLSESESDEEVTG 4096
            K +DFQ+ VT++EA+ L G NINP   V  G Q++ T     TN PFYNE+F F+   +RL + +L+++I    S++   +A RI      G F +D           F +KWAPL DP+   +G KG+VK+ +SV   GD P  P       + +IE NLL+P  V    R    + V +Y+AE LP + T ++ ++  A++ +   L D YV VSF G  G T V     +P WN+Q+ F E FPP    LR+ +RDN  + D  ++T  +DL++I  +G     GF PT+GP+W+ LYG+       +L    Q  N+ L EG+ +RGRL++A+                                              QP S           S + V+V    P+        E +LLFG ++E T+I+  L K  KP++ E+SIG  G   +        D    +S  E  P            E + + +  Q       +  Y  +P +++KPCL + +  ED+  R+   N + K+   L   +++   +         RR    +   L  ++E++V+G +  C G  ++TM     LD    +L+   L  M  +   L   L+ +N+   +     L+  L     +PQ  LPD+ ++M     RVAYARI A++I++S +  E+G  CG + ++ L       +       + A+L+++LWLGL +  +     LP     E  SG     Y D  D   FQLR +L+ AR V+ +DDSGLSDPFAR++IS     + +  QT SP+WDE L+ D +I +   + L+  PP VV+ +FD +      FLGR F  P+V +  D Y   +LQ++ + +G  AAGE++A F+L+E+D     + +V      +D+  +   I+ +         L +P  +RP L  FR E+L WG+R L R   VHL             F + +P++ +++AG R+ES+ + ++   PNF + +  + + LP      PP++I       FG   +VG+  + +++ +      D        E  +  +        +L  AG   + +L    +      + +  +++E+ P+P                    EEM   DWW++YYA++ +        + +++  +++    ++G
Sbjct:  223 KAQDFQVGVTVLEAQKLVGVNINPYVAVRVGDQRKVTATLRGTNCPFYNEYFLFEFHETRLHLQDLLLEITAFHSQTLPFMATRI------GTFRMDLGMALDQPDGHFHQKWAPLHDPRDTRAGTKGFVKITLSVRARGDLPLPPPPPCPGTSSDIEKNLLLPHGV-QAERPWARLRVRVYRAEGLPTVRTGLLGSLARALHDQ-NVLLDPYVRVSFLGQQGETSVRGEETAPKWNEQLSFVELFPPLTRSLRLQLRDNAPLVDVALATHVLDLRQISNSGRAA--GFNPTFGPAWVPLYGS---LPSGRLRDDLQSLNEGLGEGIWFRGRLLVAVSMEVYEGRVEPKPSQTTQRSGLSRLTGKKKKKKEKTRQGQTPAGILQPASASTSEDAPEIPSAMEVEVEDLLPLPENALASFEDFLLFGVLFEATMIDPSLAK--KPISLEISIGHAGRQEEQSGQGSRADEGSESSTLEVQPLLESEDRGAGQEEQELLGTPAQWPEPVDGNGPYLCLPLRHRKPCLHVWSCWEDYTWRLQSSNSVCKVAERLDHGLQEVEKM--------QRRSGPGACTRLKQTLEELVAGSRQFCHGAERRTMTRPNALDRCRAKLLTHSLNLMARQGLRLLRSLRLNNMQRTVVLAKKLLARLRFLAQEPQPPLPDVLVWMFSGQRRVAYARIPAQDILYSVVEEERGRDCGKIQSLLLT------VPGAAPGEVCAKLELFLWLGLGKQAKACTSELPMDLLPEPSSGLPQSLYRD--DFRYFQLRAHLYQARGVLAADDSGLSDPFARVLISTQCQTTRVLEQTLSPLWDELLVFDQLIVDGRREHLREEPPLVVINVFDHNKFGPAVFLGRAFAAPRVKLIEDPYQRPELQFFPLRKGPQAAGEVIATFELIELDYSGHLEPSVPSDVEPRDLASLVEPISGH---------LSLPPSVRPVLRAFRVEVLFWGLRGLGR---VHL-------------FEIEKPQVVLEVAGRRVESEVLPNYRENPNFTELVRHVTVDLPEQPYLQPPLSILVIERRAFGRTVLVGSHIVPHMLRFILQGHEDPQEEEETEEETRDLVPHGPQGEKSLPEAGTSRQ-LLKAPLKKLTLGLLGQGPELEEDIPDP--------------------EEM---DWWSKYYASLQEFQGQPSSDDEMDEAGDADGTHLISG 1346          

Query: 4685 NPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFF--AETMIEDDDGSQI---KSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAE-DCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCD-PFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXC-----------------------------VELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKM 6223
             P+  +VRVYI+KA NL P+D NGK+DPY++V  G ++   +E YIPK LNP+FG+ +EL V+ P +  L V ++D D +  DDLIGET IDLENR+ S H+ +CG+   Y  +GY  W+D   P+ IL  LC+   +P+P Y      V +  R F   +E    DD   ++    S E  AL VL  W E+   G +LVPE++ETRPLY P  PG+ QG L MW+D++P+    P P+DI PR+ I YELR  +  T+ V L +VN  T E++ DI+VKSW+K  + D Q+TDVH+ SL+G+G FNWRFV+ FDYL  E +  V  +   + ++E E++ P  L +QV D   I ++  +G  + +L    + A+    C     L  A  + NLFR  ++RGWWP++     ED + E  E   G                              VE E EL+T EEAE  PVG GR EP PLE P RP  SF  F+NP  T  +FI  R   IL+ + ++ +  + + L  Y  PG IS  I + +
Sbjct: 1444 RPIKLLVRVYIVKATNLAPADPNGKADPYVVVSAGKEQRDTKERYIPKQLNPIFGEVLELSVSLPAQPELTVAVFDHDLVGSDDLIGETHIDLENRFYSHHRANCGLASQYDVNGYNAWRDAFRPSQILAGLCQRCGLPVPEYR--AGAVKVGSRVFLTPSEAPPPDDRKPKVTSEASEEAQALHVLRRWQEMPGLGIQLVPEHVETRPLYHPRSPGLLQGSLHMWIDIFPSDVPAPPPVDIKPRQPISYELRVVIWNTDDVALDDVNPLTGERSSDIYVKSWVKGLEQDRQETDVHFNSLTGEGNFNWRFVFRFDYLPTEREVSVRRKPGPFALEEAEFRQPAVLVLQVWDYDRISANDFLGSLELQLPDMVRGARDPEHCSVRLALDGAGPRCNLFRCHRLRGWWPVVKMKDMEDVEREAREAQAGKKRKRKRRAGRPEDLEFTDTGGNVYILTGKVEAEFELLTVEEAEKRPVGKGRKEPEPLEKPNRPKTSFNWFVNPLKTFIFFIWRRYWRILVLLLLLALITIFLLLVFYTIPGQISEVIFSPV 1991          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEYFSPSTGSDNFGSDAFNFPVYN 550
            M+L+V +++L G     D+ ++L FR   +K+ ++        G+ F WP        + L ++  N +RV   + LG L I+   L +   + +RE LVDER++++ I V  +++Y  P   +  +  + F  P+ +
Sbjct:    1 MALTVCVRHLTGLPGTHDRQVRLCFRGFTQKTRKIHCGREADVGELFRWPHYGSPLAGESLSVQVVNCSRVFSPRPLGTLVISLQQLQSAGHLVLREALVDERLRVSPIQVELDLKYQPPEGAAGTWAEEDFGTPIRD 138          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVA----------------------SEKEPTPENQYVHSM--TQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENK---LRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P S +  D+QISVT++EAR L G N++P+  V  G++K+ T +K  TN P+YNE+F FD  +    M + IIKI  +   N      + +G ++G F +D  +VYT   H F  KWA L DP   T+G KGYVK DI+V+  GD  K P      +  +IE NLL+P  V  + R+     V IY+AE LP MNT+I++N+K A  GE + L D YV V FAG  G+T V   +Y P WN+Q+IFTE FPP   RL++ +RD+D V D  I T FIDL+K+   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RL+I+I      T+     S   V + P + +S +  GK E + LFG   E T+I+  +G   KP++FE++IG  GN +D  +K A                      S +E   ++  + S+  T        D  YFH+PY  KKPC+++ +  +D R R++  NI++K+  +L E +     +I  EK    RR L+  +  L  S  + V+     +  + +T LD +  +    ++E M  + + +  ++KR+ V +K++     ++ L     +PQ+ +PD+FI+MI  N R+AYARI +++I++S +  E G  CG +  V+L RL          + +QA+L++YLWLGL +  + + +GLP G+   +   G     +PP  + Y  + +FQLR +++ AR++  +D SGLSDPFAR+  S H   + + ++T  P WD+ L+ DN+        L+  PP +V+E++D D+    EF+GR F +P   +  + Y   +    L+++ IYRG  AAG++LAAF+L+++    +      LP +               G  D ++   L +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+T L
Sbjct:  249 MEPSSGRPVDYQISVTVIEARQLVGLNMDPVVCVEIGEEKKYTSMKESTNCPYYNEYFVFDFHVPPDVMFDKIIKISVIHSKN-----LLRSGTLVGTFKLDVGTVYTQPEHQFHHKWAMLSDPDDITTGCKGYVKCDIAVVGKGDNIKTPHKASEADEDDIEGNLLLPEGVP-SERQWARFYVKIYRAEGLPKMNTSIMANVKKAFIGENRDLVDPYVLVQFAGQKGKTSVQKSSYEPIWNEQVIFTEMFPPLCRRLKVQIRDSDKVNDVAIGTHFIDLRKVSNDGDK---GFLPTMGPAWVNMYGSTRNYT---LMDEHQDLNEGLGEGVSFRARLLISIAVEILDTTSAEIMSSTEVHMEPVSNISESATGKMEEFFLFGSFLEATMIDRKIGD--KPISFEVTIGNYGNQIDGVSKPALAKKKKEGGGESEEEESELIHNSSEEEAEDDGDLTSVPSTPPMKPVITDRNYFHLPYFEKKPCIYIKSWWQDQRRRLYNSNIMDKIADKLEEGLNDVQEIIKTEKAYPERR-LRGVLEELSTSCSRFVTLANKDQNLSGRTKLDRERLKSCMREMESMGQQAKTIRTQVKRNTVRDKLKLVLNFLQRLRFLADEPQHSIPDVFIWMISNNKRIAYARIPSKDILYSIVDEEMGKDCGKVKAVFL-RLPGKKGFGPAGWTVQAKLEMYLWLGLNKQRKDFLIGLPSGFEENKAVKGIGIQAVPPISLVYNMKQVFQLRAHMYQARSLFAADTSGLSDPFARVFFSTHSQVTEVLSETLCPTWDQLLVFDNVELYGEAGELRDDPPIIVIELYDQDTVGKAEFIGRTFAKPLTKMVDEHYGPPRFPPQLEYYQIYRGNCAAGDLLAAFELLQIGPAGR----AALPPID--------------GPTDSDRGPILPVPLGIRPVLSRYRIEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSALIQNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYILVGSHAVTTL 1234          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDD-NFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAP-IDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC--DPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            ++ +M+Y  ELE+  +FG F D   +F+LYRGK  +DDD N  + DR  G FKG++C+Y +   +    +   +                                     + +++++   +P++ +VR+YII+A +LHP+D+NGK+DPYI++KLG  ++RD+ENYI K LNPVFGK  ++E TFP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D + P  IL  LC+E  +  P Y     RV + +R F   T IED+ G + ++ E LAL VL HW EI   G KL+PE++ETRPL  P+KPGI+QG +EMWVDM+P     P P IDI+PRK   YELR  +  T++V L + ++FT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWRFV+ FDYL AE+ IV ++K S++  DE EYK P  L +QV D+    +D  +G  +  L+KFP+ AK  + C  D           ++F+ K+V+GWWP +   ++++ +          VE E+ L+TAEEAE +PVGLGR +P PLE P RPD S + F+NP  +I+YFI +  +W+++K   + + LL++ LF+Y+ PG     +V K+ G
Sbjct: 1399 VDELMVYNKELES--EFGSFEDWLHTFNLYRGKAGDDDDHNVVDEDRIVGRFKGSLCMYKLPLSEEITREAGFDP-----------------------------------NMGMFQSIPHNDPINVLVRIYIIRATDLHPADINGKADPYIVIKLGKSDIRDKENYISKQLNPVFGKSFDIEATFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRYYSKHRATCGIASNYSVHGYNVWRDPQKPAQILAKLCKEGKLDGPHYGP-GGRVKVANRIFLGPTEIEDESGLKKQTEEHLALTVLRHWEEIPRVGCKLIPEHVETRPLLNPDKPGIEQGRIEMWVDMFPMDVPAPGPAIDISPRKPKRYELRVIIWNTDEVILEDDDYFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFVFPFDYLMAEEKIVISKKESMFSWDETEYKIPARLTLQVWDADHFSADDFLGAIELDLNKFPRGAKTAKQCSLDMVLKEHELPTISIFKQKRVKGWWPFVAQNENDEFELTGK------VEAELHLLTAEEAEKSPVGLGRNDPEPLEKPNRPDTSLMWFMNPLRSIRYFIWHNYRWLILKALALLLLLLLVGLFLYSIPG----YLVKKLLG 1991          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSAN-IYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEY 487
            M+L V+LK +      GD+  K+ FR +   S  L+   +   F Q F WPI  ++D +++L ++ +N ++V  ++L+G  ++    ++ E  + V + L+D+        ++ EI+Y
Sbjct:    1 MALVVHLKTVTELRGKGDRIAKVTFRGLSFFSRVLENCEDEARFEQAFRWPIGSQVDGDEMLEIQVFNYSKVFTNRLIGTFRMVLQKVVEEGHLEVSDTLIDDNNTAIQTTISIEIKY 118          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNG-KPLTFEMSIGITGNLLDDYAKVAS---EKEPTPENQY-------------------VHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P + +  D+Q+S+T++EAR L G N++P+  V  G  K+ T +K  TN P+YNE+F FD  +S   M + IIKI  +   N      + +G ++G F +D  +VY+   H F  KWA L DP   ++G KGYVK D++V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT++++N+K A  GE K L D YV+V FAG  G+T V   +Y P WN+Q++FT+ FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RLM+ +      TS    +S   V V    PVS +  G+ E + LFG   E ++I+    KNG KP+TFE++IG  GN +D  ++       KEP  E +                    V S    R   T D  YFH+PY  +KPC+++ +   D R R++  NI++ +  +L E +     +I  EK+   RR L+  +  L     + +S     +G + +T LD +  +    +LE M  + ++L  ++KR  V +K+R C   ++ L     +PQ+ +PD+FI+M+  N R+AYAR+ +++++ S +  E G  C  + T++LK L       +  + +QA+L++YLWLGL +  + +  GLP G+   +   G      PP  + Y  +  FQLR +++ AR++  +D SGLSDPFAR+        + +  +T  P WD+ L+ DN+        L+  PP +V+EI+D DS    +F+GR F +P V +  + Y   +    L+++ IYRG+  AG++LAAF+L+++    K           D+  +   ++ +R   M      +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:  243 MEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKN-----LLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVP-PERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRNYT---LLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPELTSSTEVQVEQATPVSESCTGRMEEFFLFGAFLEASMIDR---KNGDKPITFEVTIGNYGNEVDGMSRPLRPRPRKEPGDEEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQIT-DRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERR-LRGVLEELSCGCHRFLSLSDKDQGRSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFSIVEEELGKDCAKVKTLFLK-LPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGSATAGDLLAAFELLQIGPSGK----------ADLPPINGPVDMDRGPIMP-----VPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSL 1225          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFN-----LFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            I+ + +YP ELE+  +F  F D   +F+L RGK  +D+D     +R  G FKG++C+Y +   +    +   +                                    T  +++ +   +P++ +VR+Y+++A +LHP+D+NGK+DPYI +KLG  ++RD+ENYI K LNPVFGK  ++E +FP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   P+ IL  LC+E  V  P +     RV + +R F   + IED++G +  + E +AL  L HW +I   G +LVPE++ETRPL  P+KPGI+QG LE+WVDM+P     P  P+DI+PRK   YELR  V  T++V L + +FFT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWR+++ FDYL AE+ IV ++K S++  DE EYK P  L +Q+ D+    +D  +G  +  L++FP+ AK  + C    +  A  + +     +F+ K+V+GWWPL+   ++++ +          VE E+ L+TAEEAE NPVGL R EP PLE P RPD SF+ FLNP  + +YF+ +  +W+L+K  ++F+ LL+ ALF+Y+ PG ++  I+
Sbjct: 1405 IDELKVYPKELES--EFDSFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDP-----------------------------------TYGMFQGIPSNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGP-HGRVRVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQC---TMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK------VEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKFLLLFLLLLLFALFLYSLPGYLAKKIL 1995          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIY-FGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEY 487
            M+L V+LK +      GD+  K+ FR     S  L+    +  F + F WP+A  +D+N++L ++ +N ++V  +KL+G   +    ++ E  + V + L+D+   I    ++ E+ Y
Sbjct:    1 MALIVHLKTVSELRGKGDRIAKVTFRGQSFYSRVLENCEGVADFDETFRWPVASSIDRNEVLEIQIFNYSKVFSNKLIGTFCMVLQKVVEENRVEVTDTLMDDSNAIIKTSLSMEVRY 118          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIA-----IKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNG-KPLTFEMSIGITGNLLDDYAKVAS---EKEPTPENQY-------------------VHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P + +  D+Q+S+T++EAR L G N++P+  V  G  K+ T +K  TN P+YNE+F FD  +S   M + IIKI  +   N      + +G ++G F +D  +VY+   H F  KWA L DP   +SG KGYVK D++V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT++++N+K A  GE K L D YV+V FAG  G+T V   +Y P WN+Q++FT+ FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RL++      + TS    +S   V V    P+S + AGK E + LFG   E ++I+    +NG KP+TFE++IG  GN +D  ++       KEP  E +                    V S    R   T D  YFH+PY  +KPC+++ +   D R R++  NI++ +  +L E +     +I  EK+   RR L+  +  L     + +S     +G + +T LD +  +    +LE M  + + L  ++KR  V +K+R C   ++ L     +PQ+ +PDIFI+M+  N RVAYAR+ +++++ S +  E G  C  + T++LK L       +  + +QA++++YLWLGL +  + +  GLP G+   +   G      PP  + Y  +  FQLR +++ AR++  +D SGLSDPFAR+        + +  +T  P WD+ L+ DN+        L+  PP +V+EI+D DS    +F+GR F +P V +  + Y   +    L+++ IYRG   AG++LAAF+L+++          G     D+  +   ++ +R   M      +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:  244 MEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKN-----LLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISSGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVP-PERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRNYT---LLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSNPELTSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDR---RNGDKPITFEVTIGNYGNEVDGLSRPQRPRPRKEPGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVT-DRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYPERR-LRGVLEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFSIVEEETGKDCAKVKTLFLK-LPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQI----------GPAGKADLPPINGPVDVDRGPIMP-----VPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSL 1226          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEI-VPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFN-----LFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            I+ + +YP ELE+  +F  F D   +F+L RGK  +D+D     +R  G FKG++C+Y +   +    +   +                                    T  +++ +   +P++ +VRVY+++A +LHP+D+NGK+DPYI ++LG  ++RD+ENYI K LNPVFGK  ++E +FP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   P+ IL  LC++  V  P +     RV + +R F   + IED++G +  + E +AL  L HW +I   G +LVPE++ETRPL  P+KPGI+QG LE+WVDM+P     P  P+DI+PRK   YELR  +  T++V L + +FFT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWR+++ FDYL AE+ IV ++K S++  DE EYK P  L +Q+ D+    +D  +G  +  L++FP+ AK  + C    +  A  + +     +F+ K+V+GWWPL+   ++++ +          VE E+ L+TAEEAE NPVGL R EP PLE P RPD SF+ FLNP  + +YF+ +  +W+L+K+ ++ + LL++ALF+Y+ PG +   I+
Sbjct: 1405 IDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDS-----------------------------------TYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGP-PGRVKVANRVFTGPSEIEDENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQC---TMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK------VEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1995          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIY-FGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEY 487
            M+L ++LK +      GD+  K+ FR     S  L+   ++  F + F WP+A  +D+N++L ++ +N ++V  +KL+G  ++    ++ E  + V + L+D+   I    +  E+ Y
Sbjct:    1 MALLIHLKTVSELRGRGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNEMLEIQVFNYSKVFSNKLIGTFRMVLQKVVEESHVEVTDTLIDDNNAIIKTSLCVEVRY 118          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNG-KPLTFEMSIGITGNLLDDYAKVAS---EKEPTPENQY-------------------VHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P + +  D+Q+S+T++EAR L G N++P+  V  G  K+ T +K  TN P+YNE+F FD  +S   M + IIKI  +   N      + +G ++G F +D  +VY+   H F  KWA L DP   ++G KGYVK D++V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT++++N+K A  GE K L D YV+V FAG  G+T V   +Y P WN+Q++FT+ FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RLM+ +      TS    +S   V V    PVS +  G+ E + LFG   E ++I+    KNG KP+TFE++IG  GN +D  ++       KEP  E +                    V S    R   T D  YFH+PY  +KPC+++ +   D R R++  NI++ +  +L E +     +I  EK+   RR L+  +  L     + +S     +G + +T LD +  +    +LE M  + ++L  ++KR  V +K+R C   ++ L     +PQ+ +PD+FI+M+  N R+AYAR+ +++++ S +  E G  C  + T++LK L       +  + +QA+L++YLWLGL +  + +  GLP G+   +   G      PP  + Y  +  FQLR +++ AR++  +D +GLSDPFAR+        + +  +T  P WD+ L+ DN+        L+  PP +V+EI+D DS    +F+GR F +P V +  + Y   +    L+++ IYRG   AG++LAAF+L+++    K           D+  +   ++ +R   M      +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:  259 MEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKN-----LLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVP-PERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRNYT---LLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPELTSSTEVQVEQATPVSESCTGRMEEFFLFGAFLEASMIDR---KNGDKPVTFEVTIGNYGNEVDGTSRPQRPRPRKEPGDEEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQIT-DRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERR-LRGVLEELSCGCHRFLSLSDKDQGHSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFSIVEEELGKDCAKVKTLFLK-LPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQTFQLRAHMYQARSLFAADSTGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPSGK----------ADLPPINGPVDMDRGPIMP-----VPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSL 1241          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFN-----LFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            I+ + +YP ELE+  +F  F D   +F+L RGK  +D+D     +R  G FKG++C+Y +   +    +   +                                    T  +++ +   +P++ +VR+Y+++A +LHP+D+NGK+DPYI +KLG  ++RD+ENYI K LNPVFGK  ++E +FP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   P+ IL  LC+E  V  P +     RV + +R F   + IED++G +  + E +AL  L HW +I   G +LVPE++ETRPL  P+KPGI+QG LE+WVDM+P     P  P+DI+PRK   YELR  V  T++V L + +FFT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWR+++ FDYL AE+ IV ++K S++  DE EYK P  L +Q+ D+    +D  +G  +  L++FP+ AK  + C    +  A  + +     +F+ K+V+GWWPL+   ++++ +          VE E+ L+TAEEAE NPVGL R EP PLE P RPD +F+ FLNP  +IKY I  R KW++IKI +  + LL++ALF+Y+ PG     +V K+ G
Sbjct: 1401 IDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDP-----------------------------------TYGMFQGIPSNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGP-HGRVKVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQC---TMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK------VEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKIVLALLGLLMLALFLYSLPG----YMVKKLLG 1992          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIY-FGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEY 487
            M+L V+LK +       D+  K+ FR     S  L+   ++  F + F WP+A  +D+N++L ++ +N ++V  +KL+G  ++    ++ E  + V + L+D+   I    ++ E+ Y
Sbjct:    1 MALIVHLKTVSELRGRADRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNEVLEIQIFNYSKVFSNKLIGTFRMVLQKVVEENRVEVSDTLIDDNNAIIKTSLSMEVRY 118          

Query:  710 KLPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPK-RPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTS---------------------------------YQPDSSKIGVDVRPCNPVSNT-------------VAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTP------------ENQYVHSMTQSRFAYTYDNK---------YFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRS-NVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVK--DIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQC 3727
            KL   I    ++ +++QI++TI EAR L G NI+P+  +  G +K+ + +K  TNSPFYNE+F FD    ++ + + IIKI       +V   ++    ++G F +D  +VY   GH F  KWA L DP    +G KGY+K DISV+  GD  K  P   D EE   IE NLLIP       R      V +Y+AE LP MN++I++N+  A  G+ K L D +VEVSFAG  GRT V      P W++Q+IF E FPP   R++I V D   + D  ++T FIDL+KI       ++GFLPT+GP+WINLYG+PR  +   L+   Q  N+   EGV++RGR+++ I                                     + D ++ G   +  N  ++T             V  K E +LLFG  +E T+I+  +G   KP++FE+SIG  GNL+D  +   S+K                +    H +     + T+  K         Y ++P++ KKPC++ I+   D   R+   N++EK+   L E I +   LI + +     + +KT + + I      +S  +       +T LD K   L   +LE M  + + +  + K+  +V E + E    V+ +   + +PQ+ +PD+FI+M+  N RVAYARI ++++++S +A + G  CG + T +LK       K    +++QA++ +YLWLG ++        LP GY  E  S       PP  + Y ++ +FQLR +++ AR +I +D +GLSDPFA++    H   + I +QT SP W++ L+ ++++ +     L  SPP VVVE++D D+    E+LG     P V +    Y   +L +  I+ G L+ G++LA F+L+++        ++GLP V+  DI ++                  +P  IRP LS +R E+L WGVR++++++++                 V++P+  I+  G  ++S  I  +   PNF       ++ LP +    PP++I   +   FG   +VG   I N +  + C
Sbjct:   68 KLLTKIHDGEVRSQNYQIAITITEARQLVGENIDPVVTIEIGDEKKQSTVKEGTNSPFYNEYFVFDFIGPQVHLFDKIIKI-------SVFHHKLIGSVLIGSFKVDLGTVYNQPGHQFCNKWALLTDPGDIRTGTKGYLKCDISVMGKGDVLKTSPKTSDTEEP--IEKNLLIPNGFP-LERPWARFYVRLYKAEGLPKMNSSIMANVTKAFVGDSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEMFPPLCRRVKIQVWDEGSMNDVALATHFIDLKKIS-NEQDGDKGFLPTFGPAWINLYGSPRNHS---LMDDYQEMNEGFGEGVSFRGRILVEIAVEILSGRAQESKFSKALKELKLPSKDKDSKSSKGKDKADKTEDGKSQQASNKTNSTEVEVESFDVPPEIVPEKNEEFLLFGAFFEATMIDRKIGD--KPISFEVSIGNFGNLIDGGSHHGSKKSAESAEEDLLPLLHEGQGDVAHDVPIPMASTTHPEKPLVTEGNRNYNYLPFEAKKPCVYFISSWGDQTFRLHWSNMLEKMADFLEESIEEVRELIKISQEAPEEK-MKTVLSDFISRSSAFISEAEKKPKMLNQTTLDKKRLTLCWQELEAMCKEAKGIIQQQKKKLSVDEMIHEAQNFVEKIRFLVDEPQHTIPDVFIWMLSNNRRVAYARIASKDLLYSPVAGQMGKHCGKIKTHFLKPPG----KRPAGWSVQAKVDVYLWLGSIKHASAILDNLPVGYEAEMSSKGAGTNHPPSNLLYQEQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVVELYDSDAVGKPEYLGATVAAPVVKLADQDYEPPRLCYHPIFCGNLSGGDLLAVFELLQVPPS----GLQGLPPVEPPDITQIYP----------------VPANIRPVLSKYRVEVLFWGVREMKKVQLLS----------------VDRPQALIECGGQGVKSCVIQSYKNNPNFSIQADAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTI-NYLKQFLC 1090          

Query: 4334 IMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMI-EDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCD--PFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            + +Y  +LE+  +F  F D  K+F L+RGK  EDD   +  DR  G FKG+ CIY                                          Q+   E    LR+ + +   +PV  ++RVYI+ A NL P+D +GKSDPYI++KLG  E++DR+ YIPK LNPVFG+  E++ TFP+ES L + IYD D +  DDLIGET IDLENR+ S H+  CG+   Y   GY  W+D   PT IL  LC+++ +  P +     ++ I ++ F  +T+  E+D    ++S E LAL+VLH W +I   G +LVPE+IETRPLY  +KPG++QG L+MWVDM+P     P  P+DI+PR+  GYELR T+  TE V L + N FT +K+ DI+VK W+K  + D Q+TDVHY SL+G+G FNWRF++ F YL AE  +V T++ +++ +++ E KTP  L +QV D   + SD  +G  +  L+ FP+ AK  ++CD   F+ +    K ++F+ K+VRGWWP   + +               VE E  LVTAEEAE NPVG  R EP PL  P RPD SF  F++P+  + Y I    K  +I  F++ + ++ + LFIY  PG+IS  IV
Sbjct: 1277 LQIYDGDLES--EFNNFEDWVKTFELFRGKSTEDDHGLDG-DRVIGKFKGSFCIYK---------------------------------------SPQDSSSEDSGQLRIQQGIPPNHPVTVLIRVYIVAAFNLSPADPDGKSDPYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSILIYDHDMIGTDDLIGETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFH--PGKIQIGNQVFSGKTIFTEEDTDETVESYEHLALKVLHSWEDIPEVGCRLVPEHIETRPLYHKDKPGMEQGRLQMWVDMFPKDMPQPGPPVDISPRRPKGYELRVTIWNTEDVILEDENIFTGQKSSDIYVKGWLKGLEDDKQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVITKRENIFSLEKMECKTPAVLVLQVWDFERLSSDDFLGTLEMNLNSFPRAAKSAKACDLAKFENASEETKISIFQQKRVRGWWPFSKSKELTGK-----------VEAEFHLVTAEEAEKNPVGKARKEPEPLAKPNRPDTSFSWFMSPFKCLYYLIWKNYKKYIIIAFILIILIIFLVLFIYTLPGAISRRIV 1854          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSY----QPD-SSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKV---------------------ASEKEPTPENQYVHSMTQSRFAYTYDNK----YFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGK-----MPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNI-IFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENK---LRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESA-----------DWWTRYYATIGDLGDSTIVKEVIEKLSESESDEEVTGFVLXXXXXXXXXXXXXXXXXXXXXXXPXXXXXXXXXXXXXXXXXXNPFQPSTKELFLKEEPDNLRMESEYVTDNSWIERIMMYPCELENVKDFGGFHDPFKSFSLYRGK-QEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSE--ACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            ++P S +  D+QISVT+VEAR L G N++PM  V  G+ K+ T +K  TN P+YNE+F FD  +    M + I+K+  +   N      + +G ++G F +D  ++Y+   H F+ KWA L DP+  ++G KGYVK D++V+  GD  K P   +  E  +IE NLLIP  V    R+     + IY+AE LP MNT+I++N+K A  GE K L D YV+V FAG  G+T V    Y P WN+QI+FTE FPP   R++I +RD+D V D  I T F+DL+ I   G K   GFLPT GP+W+N+YG+ RT+T   L+   Q  N+ L EGV++R RL+I +         PD S+   V +     +S T  GK E + LFG   E T+I+  +G   KP+ FE++IG  GN +D  A+                      +SE+E   +       T         ++    YFH+PY  +KPC+++ +  +D R R+F  NII+ +  +L + +     +I  EK    RR L+  +  L     + +S     +  + +T LD +  +L   ++E +  + + +  ++K+S V +K++     +  L     +PQ+ +PD+FI+MI    R+AYAR+ +++I++S++  E G  CG + T++L R+          + +Q++++IYLWLGL R  + Y  GLP G+     S        PP  + Y+ + +FQLRV+++ AR++  +D +GLSDPFAR+  S     + I  +T  P WD+ L+ +N+ +F  A + L+  PP +V+EI+D D+    EF+GR F +P V +  + Y   +    L+++ IYRG   AGE+LAAF+L+++    K      LP +               G  D ++   L +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+ +L  +        +R  DK              N  + T  I+  G E E G    + T +K +  +  V      ++ ++K      ++               DWW++Y+A+I  L ++   +E     SE   D ++                 +      PDD P K  K+ K +K KK+   +PF+    +L      D L++                Y  ELE+  ++  F D   SF+L+RGK  +EDD N  + DR  G FKG++C+Y +                                      ++ +R+   + T+ +++N+   +P++ +VR+Y+I+A +LHP+D+NGK+DPYI +KLG  E++D+ENYI K LNP+FGK  ++E TFP +S L V IYDWD +  DDLIGET +DLENR+ S H+ +CGI  +Y  HGY  W+D   PT IL  LC+E  +  P Y     RV +++R F A T IEDD+G + ++ E LAL VL HW EI   G KLVPE++ETRPL  P+KPGI+QG +EMWVDM+P     P  P+DI+PRK   +ELR  +  T++V L + + FT EK+ DIFV+ W+K    D Q TDVHY S++G+G FNWRFVY FDYL AE+ IV ++K S++  DE EYK P  LN+QV D+    +D  +G  +  L++FP+ AK  + C    ++        ++F+ K+++GWWP +   +D++ +          VE E+ L+T EEAE +PVG GR EP PLE P RPD + L FL P+  +K+ I  +  W+ IKI    + L I+ALF+YN PG     +V KM G
Sbjct:   45 MEPSSGRPVDYQISVTVVEARQLIGLNMDPMVCVEIGEDKKYTSMKESTNCPYYNEYFVFDFHVPPDVMFDKILKLSVIHSKN-----LLRSGTLVGTFKLDVGTIYSQPEHQFYHKWALLSDPEDISAGCKGYVKCDVAVVAKGDTIKTPHKANESEEDDIEGNLLIPEGVP-AERQWARYYLKIYRAEGLPRMNTSIMANVKKAFIGENKDLVDPYVQVQFAGQRGKTSVQKSCYEPIWNEQIVFTEMFPPLCKRMKIQLRDSDKVNDVAIGTHFLDLRTISNDGDK---GFLPTLGPAWVNMYGSTRTYT---LMDEYQELNEGLGEGVSFRARLLICLGVEILDPSSPDISNSTDVQLEGIPNISETATGKVEEFFLFGSFLEATMIDRKIGD--KPINFEVTIGYYGNEMDGAARPKTKGKKGGGDGGEEETELIHNSSEEETDEDGDLTSVATTPPMKPVITDRMVRNYFHLPYFERKPCVYIKSWWQDQRRRLFNANIIDNVADKLEDGLNDVQEIIKTEKTYPERR-LRGVLEELSHGCSQFLSLANQDQNLSGRTKLDRERLKLCMSEVESIGQQAKAMRTQVKKSTVRDKIKLAQNFLTRLRFLADEPQHSVPDVFIWMISNGKRIAYARVPSKDILYSAIREETGKDCGKVKTIFL-RIPGKKGFGPAGWTVQSKIEIYLWLGLTRQRKDYLRGLPNGFEENKLSKGPGMPCSPPISLTYMMKQIFQLRVHMYQARSLFAADSTGLSDPFARVFFSTQSQVTEILAETLCPTWDQLLVFENVELFGEATE-LRDDPPIIVIEIYDQDTVGKAEFMGRTFAKPVVKMADEHYGPPRFPPQLEYYQIYRGNCTAGEMLAAFELLQIGPNGK----ADLPPID--------------GPTDVDRGPILPVPLGIRPVLSKYRIEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSALIPNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSIAVPSLRKFI-------YRATDKQA------------NNFSTTGEIIVVGLEPEPGFKKMD-TVVKLDSGSDAVVKVEVSSLHRIKKFKKDDDKDGDEIEEEELDESMLDWWSKYFASIETLTEALKAQEAALSDSEDRDDMDIA----------------DGGAEIKPDDSPVKGPKRGKGKKDKKKHTIDPFEKKKPKL------DELKV----------------YSKELES--EYDNFEDWLHSFNLFRGKGGDEDDQNVTDEDRIVGKFKGSLCMYKV-------------------------------------SDEMQRDVSFESTMGMFQNIPHNDPINVLVRIYVIRATDLHPADINGKADPYIAIKLGKTEIKDKENYISKQLNPLFGKSFDVEATFPMDSTLTVSIYDWDLVGTDDLIGETKLDLENRYYSKHRATCGITCNYAIHGYNVWRDPMKPTQILAKLCKEGKLDGPHYGP-GGRVKVENRVFMAATEIEDDNGLKRQTDEHLALTVLKHWEEIPRVGCKLVPEHVETRPLLHPDKPGIEQGRIEMWVDMFPKDMTAPGPPLDISPRKPKKFELRVIIWNTDEVVLEDDDIFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSITGEGNFNWRFVYPFDYLMAEEKIVISKKESMFAWDETEYKIPARLNLQVWDADHFSADDFLGAIELDLNRFPRGAKSAKQCSIEMVTNEGEMPTVSIFKQKRIKGWWPFVARNEDDEFELTGK------VEAELHLLTGEEAERSPVGEGRNEPEPLEKPNRPDIALLWFLIPFKAVKHLICDQYMWLTIKIVTALLLLAILALFLYNMPG----YMVKKMLG 1780          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNG-KPLTFEMSIGITGNLLDDYAKVAS---EKEPTPENQY-------------------VHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLR-IPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLN-----LFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPV----------PGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKEVIE-KLSESESDEEVTGFVLXXXXXXXXXXXXXXXXXXXXXXXPXXXXXXXXXXXXXXXXXXNPFQPSTKELFLKEEPDNLRMESEYVTDNSWIERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFN-----LFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            ++P + +  D+Q+S+T++EAR L G N++P+  V  G  K+ T +K  TN P+YNE+F FD  +S   M + IIKI  +   N      + +G ++G F +D  +VY+   H F  KWA L DP   ++G KGYVK D++V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT++++N+K A  GE K L D YV+V FAG  G+T V   +Y P WN+Q++FT+ FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RLM+ +      TS    +S   V V    P+S +  GK E + LFG   E ++I+    KNG KP+TFE++IG  GN +D  ++       KEP  E +                    V S    R   T D  YFH+PY  +KPC+++ +   D R R++  NI++ +  +L E +     +I  EK+   RR L+  +  L     + +S     +  + +T LD +  +    +LE M  + + L  ++KR  V +K+R C   ++ L     +PQ+ +PD+FI+M+  N R+AYAR+ +++++ S +  E G  C  + T++LK L       +  + +QA+L++YLWLGL +  + +  GLP G+   +   G      PP  + Y  +  FQLR +++ AR++  +D SGLSDPFAR+        + +  +T  P WD+ L+ DN+        L+  PP +V+EI+D D+    +F+GR F +P V +  + Y   +    L+++ IYRG   AG++LAAF+L+++    K      LP +            N   +MD+  +  +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+  +++L  +        +R  D++     +   L      L+N G  +          E    + +L  M +     D    V                 + +  +  +    DWW++Y+A+I  + +    +E     L E E  +   G               EE         P     +  +  +KK+   +  +PS  +++ KE      +ESE+     W+                        +F+L RGK  +D+D     +R  G FKG++C+Y +                                      E   RE     T  +++ +   +P++ +VRVY+++A +LHP+D+NGK+DPYI ++LG  ++RD+ENYI K LNPVFGK  ++E +FP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   P+ I+  LC+E  V  P +     RV + +R F   + IED++G +  + E +AL  L HW +I   G +LVPE++ETRPL  P+KPGI+QG LE+WVDM+P     P  P+DI+PRK   YELR  V  T++V L + +FFT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWR+++ FDYL AE+ IV ++K S++  DE EYK P  L +Q+ D+    +D  +G  +  L++FP+ AK  + C    +  A  + +     +F+ K+V+GWWPL+   ++++ +          VE E+ L+TAEEAE NPVGL R EP PLE P RPD +F+ FLNP  +IKY I  R KW++IK  +  + LL++ALF+Y+ PG     +V K+ G
Sbjct:  265 MEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKN-----LLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVP-PERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDMAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRNYT---LLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPELTSSTEVQVEQATPISESCTGKVEEFFLFGAFLEASMIDR---KNGDKPITFEITIGNYGNEVDGLSRPQRPRPRKEPGDEEEVDLIQNSSDDETDEAGDLASVSSTPPMRPQIT-DRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERR-LRGVLEELSCGCCRFLSLADKDQSHSSRTRLDRERLKSCMRELESMGQQAKTLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFSIVEEELGKDCAKVKTLFLK-LPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDTMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPAGK----ADLPPI------------NGPVDMDQGPIMPVPMGIRPVLSKYRIEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHTVSSLRRFV-------YRPPDRSAPSWNTAGRLPRGCHVLYNGGPSSHPAGEVVVNMELEVPVRKLETMVKLDATSDAVIKVDVADEEKEKKKKKKGSSEEMEEEEPDESMLDWWSKYFASIDTMKEQLRQQEASGIDLEEKEEMDNTEGLKGLMKGKEKARAAKEEKKKRAQSLGP----GQVSEAPEKKKPKIDELKPSLAQVYPKE------LESEFDNFEDWLH-----------------------TFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKV-----------------------------------PLPEDVSREAGYDPTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGISQTYSTHGYNIWRDPMKPSQIVTRLCKEGKVDGPHFGP-PGRVKVSNRVFTGPSEIEDENGQRKPTEEHVALLALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQC---TMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK------VEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKTVLALLGLLMLALFLYSLPG----YMVKKLLG 2022          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEA-NLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNG-KPLTFEMSIGITGNLLDDYAKVAS---EKEPTPENQY-------------------VHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLR-IPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLN-----LFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPV----------PGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKEVIE-KLSESESDEEVTGFVLXXXXXXXXXXXXXXXXXXXXXXXPXXXXXXXXXXXXXXXXXXNPFQPSTKELFLKEEPDNLRMESEYVTDNSWIERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFN-----LFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            ++P + +  D+Q+S+T++EAR L G N++P+  V  G  K+ T +K  TN P+YNE+F FD  +S   M + IIKI  +   N      + +G ++G F +D  +VY+   H F  KWA L DP   ++G KGYVK D++V+  GD  K P   +  +  +IE  NLL+P  V    R+     V IY+AE LP MNT++++N+K A  GE K L D YV+V FAG  G+T V   +Y P WN+Q++FT+ FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RLM+ +      TS    +S   V V    P+S +  GK E + LFG   E ++I+    KNG KP+TFE++IG  GN +D  ++       KEP  E +                    V S    R   T D  YFH+PY  +KPC+++ +   D R R++  NI++ +  +L E +     +I  EK+   RR L+  +  L     + +S     +  + +T LD +  +    +LE M  + + L  ++KR  V +K+R C   ++ L     +PQ+ +PD+FI+M+  N R+AYAR+ +++++ S +  E G  C  + T++LK L       +  + +QA+L++YLWLGL +  + +  GLP G+   +   G      PP  + Y  +  FQLR +++ AR++  +D SGLSDPFAR+        + +  +T  P WD+ L+ DN+        L+  PP +V+EI+D D+    +F+GR F +P V +  + Y   +    L+++ IYRG   AG++LAAF+L+++    K      LP +            N   +MD+  +  +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+  +++L  +        +R  D++     +   L      L+N G  +          E    + +L  M +     D    V                 + +  +  +    DWW++Y+A+I  + +    +E     L E E  +   G               EE         P     +  +  +KK+   +  +PS  +++ KE      +ESE+     W+                        +F+L RGK  +D+D     +R  G FKG++C+Y +                                      E   RE     T  +++ +   +P++ +VRVY+++A +LHP+D+NGK+DPYI ++LG  ++RD+ENYI K LNPVFGK  ++E +FP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D   P+ I+  LC+E  V  P +     RV + +R F   + IED++G +  + E +AL  L HW +I   G +LVPE++ETRPL  P+KPGI+QG LE+WVDM+P     P  P+DI+PRK   YELR  V  T++V L + +FFT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWR+++ FDYL AE+ IV ++K S++  DE EYK P  L +Q+ D+    +D  +G  +  L++FP+ AK  + C    +  A  + +     +F+ K+V+GWWPL+   ++++ +          VE E+ L+TAEEAE NPVGL R EP PLE P RPD SF+ FLNP  + +YF+ +  +W+L+K+ ++ + LL++ALF+Y+ PG +   I+
Sbjct:  265 MEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKN-----LLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGRNLLLPEGVP-PERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDMAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRNYT---LLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPELTSSTEVQVEQATPISESCTGKVEEFFLFGAFLEASMIDR---KNGDKPITFEITIGNYGNEVDGLSRPQRPRPRKEPGDEEEVDLIQNSSDDETDEAGDLASVSSTPPMRPQIT-DRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERR-LRGVLEELSCGCCRFLSLADKDQSHSSRTRLDRERLKSCMRELESMGQQAKTLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFSIVEEELGKDCAKVKTLFLK-LPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDTMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPAGK----ADLPPI------------NGPVDMDQGPIMPVPMGIRPVLSKYRIEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHTVSSLRRFV-------YRPPDRSAPSWNTAGRLPRGCHVLYNGGPSSHPAGEVVVNMELEVPVRKLETMVKLDATSDAVIKVDVADEEKEKKKKKKGSSEEMEEEEPDESMLDWWSKYFASIDTMKEQLRQQEASGIDLEEKEEMDNTEGLKGLMKGKEKARAAKEEKKKRAQSLGP----GQVSEAPEKKKPKIDELKPSLAQVYPKE------LESEFDNFEDWLH-----------------------TFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKV-----------------------------------PLPEDVSREAGYDPTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGISQTYSTHGYNIWRDPMKPSQIVTRLCKEGKVDGPHFGP-PGRVKVSNRVFTGPSEIEDENGQRKPTEEHVALLALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQC---TMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK------VEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKVLLLALLLLLLALFLYSVPGYLVKKIL 2022          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEK----EPTPENQYVHSMTQSRFA----------------YTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGY--NRECFSGKM---PPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENK-LRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKEVIEKLSESESDEEVTGFVLXXXXXXXXXXXXXXXXXXXXXXXPXXXXXXXXXXXXXXXXXXNPFQPSTKELFLKEEPDNLRMESEYVTDNSWIERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDD-NFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC--DPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            I+P + ++ DFQ+SVT++EAR L G N++P+  V  G +K+ T +K  TN P+YNE+F F+  +    M + I+++  +   N      + +G ++G F +D  +VY+   H F+ KWA L DP   T+G KGYVK DI+V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT+I++N+K A  GE K L D YV+V FAG  G+T +    Y P WN+QIIFTE+FPP   R+++ +RD D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R++T   L+   Q  N+ L EGV++R RL+I++      TS    +S   V V     +S    GK E + LFG   E T+I+  +G   KP+ FE++IG  G+ +D   K  ++K    +   E++ + + +    A                   D  YFH+PY  +KPC+++ +  +D R R++  NII+ +  +L E +     +I  EK    RR L+  +  L       ++     +     T LD +  +L   +LE M  + + +  ++K+  V +K++     ++ L     +PQ+ +PD++I+M     R+AYAR+ +++++ S++  E G  C  + T++ K L          + +QA+ ++YLWLGL +  + +  GLP G+  N+      M   PP  + Y  + +FQLRV+++ AR++  +D +GLSDPFAR+  S H   + I  +T  P WD+ L+ DN+        L+  PP +V+EI+D DS    +F+GR F +P   +  + Y   +    L+++ +YRG   AGE+LAAF+L+++    K      LP +            +   +MD    L +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  I+S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+T L  +        +R  DK+     +++ + +          +    + +  S      DM    P+ D         +K + V  +  +    DWW++Y+A+I  L ++   +E  +  +E   D +  G  +        + + +    D     P +    +K             +P  +EL +     N  +ESE+     W+    +Y                       RGK  +DDD N  + DR  G FKG++C+Y +                                      ++  RE      +  ++N+   +P++ +VRVY+I+A +LHP+D+NGK+DPYI +KLG  EV+D+ENYI K LNP+FGK  +++ TFP +S L V IYDWD +  DDLIGET IDLENR+ S H+ +CGI  SY  HGY  W+D   PT IL  LC++  +  P Y     RV + +R +   T I D++G + ++ E LAL VL+HW +I   G KL+ E++ETRPL  P+KPGI+QG +EMWVDM+P     P  P+DI+PRKA  +ELR  +  T++V L + + FT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWRF+Y FDYL AE+ IV ++K S++  DE EYK P  LN+QV D+    +D  +G  +  L++FP+ AK  + C  D     +     N+F+ K+++GWWP I   ++++ +          VE E+ L+T+EEAE +PVG GR EP PLE P RPD +FL F+ P   I+YFI  + KW++IKI +  + L I+ALF+Y+ PG ++  ++
Sbjct:   61 IEPSAGRLMDFQVSVTVIEARQLVGLNMDPVVCVEIGDEKKYTSMKESTNCPYYNEYFVFEFHVPPDVMFDKILRVSVIHSKN-----LLRSGTMVGAFKMDVGTVYSQPDHQFYHKWAVLCDPDDITAGCKGYVKCDIAVVTKGDNIKTPHKANETDEDDIEGNLLLPEGVP-ADRQWARFYVKIYRAEGLPKMNTSIMANVKKAFIGENKDLVDPYVQVLFAGQKGKTSIQKSCYEPIWNEQIIFTEQFPPLCKRIKVQIRDADKVNDVAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRSYT---LMDEYQDLNEGLGEGVSFRARLLISLAVEILDTSSPEITSSPEVQVEGVPNISENATGKIEEFFLFGAFLEATMIDRKIGD--KPINFEVTIGNYGSDVDIPTKPRTKKSKKGDGDEESELIQASSDEEVADDGELSSVSTTPPMKPVITDRNYFHLPYFERKPCIYIKSWWQDQRRRLYNANIIDHIADKLEEGLNDVQEIIKTEKAFPERR-LRGVLEELSNGCSNFLTLANKDQSQTGLTKLDREKLKLCMWELETMGQQAKAMRSQVKKKTVKDKVKLAQNFLQKLRFLSDEPQHSVPDVYIWMFSNGKRIAYARVPSKDLLFSNVEEEIGKDCAKVKTIFFK-LPGKKSFGPAGWTVQAKTEMYLWLGLNKQRKDFLSGLPNGFEENKAVKGPGMHSSPPISLIYTMKQVFQLRVHMYQARSLFAADSTGLSDPFARVFFSTHSQVTEIVNETLCPTWDQLLVFDNVELYGEASELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPTTKMSDEHYGPPRFPPQLEYYQVYRGNCTAGEMLAAFELLQIGPGGK----ADLPPI------------DGPTDMDRGPILPVPIGIRPVLSKYRIEVLFWGLRDLKRVNLSQ----------------VDRPRVDIECAGKGIQSALIPNYNKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVTTLRKFI-------YRAPDKSVNSWSAMEEIVIHTEPEPAVKKMETMVKLDSASDAVVKVDM----PDDDKEGKGKKKKKKGEEVEEEQLDESMLDWWSKYFASIETLMENIKAQEAEKAEAEEREDMDADGADIKPDSNVKGNKKRKGKGKDKNKTAPGEGLADRK-------------RPKIEELKVF----NRELESEFDHFEDWLHTFNLY-----------------------RGKSGDDDDENVMDEDRLVGKFKGSLCMYKV-------------------------------------SDELYREMGIDPNMGTFQNIPHNDPINVLVRVYVIRATDLHPADINGKADPYISIKLGKSEVKDKENYISKQLNPIFGKSFDIDATFPMDSTLTVSIYDWDLVGTDDLIGETKIDLENRYYSKHRATCGIASSYAIHGYNVWRDPMKPTQILAKLCKDGKLDPPQYGP-GGRVKVANRVYTGPTEIMDENGLKKQTDEHLALAVLNHWEDIPRMGCKLIHEHVETRPLLNPDKPGIEQGRIEMWVDMFPKDMPAPGPPLDISPRKAKKFELRVIIWNTDEVVLEDDDIFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFIYPFDYLMAEEKIVISKKESMFSWDETEYKIPARLNLQVWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTLDMILNEQDMPMVNIFKQKRIKGWWPFIARDENDEMEITGK------VEAELHLLTSEEAEKSPVGEGRNEPEPLEKPNRPDTTFLWFITPLKAIRYFICNQYKWLVIKIVLALLLLAIVALFLYSMPGYMAKKLL 1788          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEK----EPTPENQYVHSMTQSRFA----------------YTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGY--NRECFSGKM---PPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENK-LRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKEVIEKLSESESDEEVTGFVLXXXXXXXXXXXXXXXXXXXXXXXPXXXXXXXXXXXXXXXXXXNPFQPSTKELFLKEEPDNLRMESEYVTDNSWIERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDD-NFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC--DPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            I+P + ++ DFQ+SVT++EAR L G N++P+  V  G +K+ T +K  TN P+YNE+F F+  +    M + I+++  +   N      + +G ++G F +D  +VY+   H F+ KWA L DP   T+G KGYVK DI+V+  GD  K P   +  +  +IE NLL+P  V    R+     V IY+AE LP MNT+I++N+K A  GE K L D YV+V FAG  G+T +    Y P WN+QIIFTE+FPP   R+++ +RD D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R++T   L+   Q  N+ L EGV++R RL+I++      TS    +S   V V     +S    GK E + LFG   E T+I+  +G   KP+ FE++IG  G+ +D   K  ++K    +   E++ + + +    A                   D  YFH+PY  +KPC+++ +  +D R R++  NII+ +  +L E +     +I  EK    RR L+  +  L       ++     +     T LD +  +L   +LE M  + + +  ++K+  V +K++     ++ L     +PQ+ +PD++I+M     R+AYAR+ +++++ S++  E G  C  + T++ K L          + +QA+ ++YLWLGL +  + +  GLP G+  N+      M   PP  + Y  + +FQLRV+++ AR++  +D +GLSDPFAR+  S H   + I  +T  P WD+ L+ DN+        L+  PP +V+EI+D DS    +F+GR F +P   +  + Y   +    L+++ +YRG   AGE+LAAF+L+++    K      LP +            +   +MD    L +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  I+S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+T L  +        +R  DK+     +++ + +          +    + +  S      DM    P+ D         +K + V  +  +    DWW++Y+A+I  L ++   +E  +  +E   D +  G  +        + + +    D     P +    +K             +P  +EL +     N  +ESE+     W+    +Y                       RGK  +DDD N  + DR  G FKG++C+Y +                                      ++  RE      +  ++N+   +P++ +VRVY+I+A +LHP+D+NGK+DPYI +KLG  EV+D+ENYI K LNP+FGK  +++ TFP +S L V IYDWD +  DDLIGET IDLENR+ S H+ +CGI  SY  HGY  W+D   PT IL  LC++  +  P Y     RV + +R +   T I D++G + ++ E LAL VL+HW +I   G KL+ E++ETRPL  P+KPGI+QG +EMWVDM+P     P  P+DI+PRKA  +ELR  +  T++V L + + FT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWRF+Y FDYL AE+ IV ++K S++  DE EYK P  LN+QV D+    +D  +G  +  L++FP+ AK  + C  D     +     N+F+ K+++GWWP I   ++++ +          VE E+ L+T+EEAE +PVG GR EP PLE P RPD +FL F++P   I+Y +    KW++IKI V  + L ++ LF+Y+ PG     +V K+ G
Sbjct:   61 IEPSAGRLMDFQVSVTVIEARQLVGLNMDPVVCVEIGDEKKYTSMKESTNCPYYNEYFVFEFHVPPDVMFDKILRVSVIHSKN-----LLRSGTMVGAFKMDVGTVYSQPDHQFYHKWAVLCDPDDITAGCKGYVKCDIAVVTKGDNIKTPHKANETDEDDIEGNLLLPEGVP-ADRQWARFYVKIYRAEGLPKMNTSIMANVKKAFIGENKDLVDPYVQVLFAGQKGKTSIQKSCYEPIWNEQIIFTEQFPPLCKRIKVQIRDADKVNDVAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRSYT---LMDEYQDLNEGLGEGVSFRARLLISLAVEILDTSSPEITSSPEVQVEGVPNISENATGKIEEFFLFGAFLEATMIDRKIGD--KPINFEVTIGNYGSDVDIPTKPRTKKSKKGDGDEESELIQASSDEEVADDGELSSVSTTPPMKPVITDRNYFHLPYFERKPCIYIKSWWQDQRRRLYNANIIDHIADKLEEGLNDVQEIIKTEKAFPERR-LRGVLEELSNGCSNFLTLANKDQSQTGLTKLDREKLKLCMWELETMGQQAKAMRSQVKKKTVKDKVKLAQNFLQKLRFLSDEPQHSVPDVYIWMFSNGKRIAYARVPSKDLLFSNVEEEIGKDCAKVKTIFFK-LPGKKSFGPAGWTVQAKTEMYLWLGLNKQRKDFLSGLPNGFEENKAVKGPGMHSSPPISLIYTMKQVFQLRVHMYQARSLFAADSTGLSDPFARVFFSTHSQVTEIVNETLCPTWDQLLVFDNVELYGEASELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPTTKMSDEHYGPPRFPPQLEYYQVYRGNCTAGEMLAAFELLQIGPGGK----ADLPPI------------DGPTDMDRGPILPVPIGIRPVLSKYRIEVLFWGLRDLKRVNLSQ----------------VDRPRVDIECAGKGIQSALIPNYNKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVTTLRKFI-------YRAPDKSVNSWSAMEEIVIHTEPEPAVKKMETMVKLDSASDAVVKVDM----PDDDKEGKGKKKKKKGEEVEEEQLDESMLDWWSKYFASIETLMENIKAQEAEKAEAEEREDMDADGADIKPDSNVKGNKKRKGKGKDKNKTAPGEGLADRK-------------RPKIEELKVF----NRELESEFDHFEDWLHTFNLY-----------------------RGKSGDDDDENVMDEDRLVGKFKGSLCMYKV-------------------------------------SDELYREMGIDPNMGTFQNIPHNDPINVLVRVYVIRATDLHPADINGKADPYISIKLGKSEVKDKENYISKQLNPIFGKSFDIDATFPMDSTLTVSIYDWDLVGTDDLIGETKIDLENRYYSKHRATCGIASSYAIHGYNVWRDPMKPTQILAKLCKDGKLDPPQYGP-GGRVKVANRVYTGPTEIMDENGLKKQTDEHLALAVLNHWEDIPRMGCKLIHEHVETRPLLNPDKPGIEQGRIEMWVDMFPKDMPAPGPPLDISPRKAKKFELRVIIWNTDEVVLEDDDIFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFIYPFDYLMAEEKIVISKKESMFSWDETEYKIPARLNLQVWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTLDMILNEQDMPMVNIFKQKRIKGWWPFIARDENDEMEITGK------VEAELHLLTSEEAEKSPVGEGRNEPEPLEKPNRPDTTFLWFISPLKAIRYLVCNNYKWLIIKIVVALLLLAMLGLFLYSMPG----YMVKKLLG 1789          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKV------------------------ASEKEPTPENQYVH-SMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENK---LRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P + +  D+QISVT++EAR L G N++P+  V  G+ K+ T +K  TN P+YNE+F FD  +    M + I+K+  +   N      + +G ++G F +D  +VY+   H F+ KWA L DP   T+G KGY+K DI+V+  GD  K P   +  +  +IE NLL+P  V  + R+     V IY+AE LP MNT+I++N+K A  GE + L D YV+V FAG  G+T V   +Y P WN+QIIFTE FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ L EGV++R RL+I++      T+     S   V + P + +S +  GK E + LFG   E T+++  +G   KP+ FE++IG  GN LD  +K                         +S++E   +   V  S T        D  YFH+PY  KKPC+++ +  +D R R++  NI++K+  +L E +     +I  EK    RR L+  +  L     + V+     +  A +T LD +  +    ++E M  + + +  ++KR+ V +K++     ++ L     +PQ+ +PD+FI+M+  N R+AYARI  ++I+ S +  E G  CG +  V+L RL          + +QA+L++YLWLGL +  + +  GLP G+   +   G     +PP  + Y  + +FQLR +++ AR++  +D SGLSDPFAR+  S H   + + ++T  P WD+ L+ DN+        L+  PP +V+EI+D D+    E++GR F +P   +  + Y   +    L+++ IYRG   AGE+LAAF+L+++    +      LP +               G  D ++   L +P  IRP LS +R E+L WG+R L+RI +                  V++P++ I+ AG  I+S    ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+T+L
Sbjct:  223 MEPSAGRPVDYQISVTVIEARQLVGLNMDPVVCVEIGEDKKYTSMKESTNCPYYNEYFVFDFHVPPDVMFDKILKLSVIHSKN-----LLRSGTLVGTFKLDVGTVYSQPEHQFYHKWAMLSDPDDITAGCKGYIKCDIAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVP-SERQWARFYVKIYRAEGLPKMNTSIMANVKKAFIGENRDLVDPYVQVQFAGQKGKTSVQKSSYEPIWNEQIIFTEMFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKIANDGDK---GFLPTMGPAWVNMYGSTRNYT---LMDEHQDLNEGLGEGVSFRARLLISVAVEILDTTSPEIMSSTEVQMEPVSNISESATGKLEEFFLFGSFLEATMVDRKIGD--KPINFEVTIGNYGNQLDGVSKPVSGKKKKREGGGESDEEESELIQNSSDEETEDDGDLVSVSSTPPMKPVITDRNYFHLPYFEKKPCIYIKSWWQDQRRRLYNSNIMDKIADKLEEGLNDVQEIIKTEKAYPERR-LRGVLEELSTGCSRFVTLANKDQNQAGRTKLDRERLKSCMREMESMGQQAKTIRSQVKRNTVRDKLKLALNFLQRLRFLADEPQHSIPDVFIWMMSNNKRIAYARIPTKDILFSIVDEEMGKDCGKVKAVFL-RLPGKKGFGPAGWTVQAKLEMYLWLGLNKQRKDFLSGLPNGFEENKAVKGTGLQAVPPISLTYNMKQVFQLRAHMYQARSLFAADTSGLSDPFARVFFSTHSQVTEVLSETLCPTWDQLLVFDNVELYGEATELRDDPPIIVIEIYDQDTVGKAEYIGRTFAKPLTKMVDEHYGPPRFPPQLEYYQIYRGNCTAGELLAAFELLQIGPAGR----TELPPID--------------GPTDVDRGPILPVPLGIRPVLSRYRIEVLFWGLRDLKRINLAQ----------------VDRPRVDIECAGKGIQSALNQNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVTSL 1209          

Query: 4337 MMYPCELENVKDFGGFHDPFKSFSLYRGKQ-EEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAP-IDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC--DPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            ++Y  ELE   +F  F D   +F+LYRGK  ++DD N  + DR  G FKG++C+Y +   D    D   +                                     + +++++   +P++ +VRVY+I+A +LHP+D+NGK+DPY+++KLG  E++D+ENYI K LNPVFGK  ++E TFP ES L V +YDWD +  DDLIGET IDLENR+ S H+ +CGI  +Y  HGY  W+D + PT IL  LC+E  +  P Y     +V + +R F   T IED++G + ++ E LAL  L HW EI   G KL+PE++ETRPL  P+KPGI+QG LEMWVDM+P     P P IDI+PRK   YELR  +  T++V L + ++FT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWRFV+ FDYL AE+ IV ++K S++  DE EYK P  L MQV D+    +D  +G  +  L++FP+ AK  + C  D     +     ++F+ K+V+GWWP +   +++D +          VE E+ L+TAEEAE +PVGLGR EP PLE P RPD S + F+NP  +++YFI +  +W+++K   + + LL++ LF+Y+ PG     +V K+ G
Sbjct: 1284 LVYNKELET--EFDHFEDWLHTFNLYRGKAIDDDDQNIVDDDRIVGRFKGSLCMYKLPLSDEITRDVGFDP-----------------------------------NMGMFQSIPHNDPINVLVRVYVIRATDLHPADINGKADPYVVIKLGKSEIKDKENYISKQLNPVFGKSFDIEATFPMESMLTVSVYDWDLVGTDDLIGETKIDLENRYYSKHRATCGIASNYSLHGYNVWRDPQKPTQILAKLCKEGKLDGPHYGP-GGKVKVANRIFLGPTDIEDENGLKKQTEEHLALTALKHWEEIPRVGCKLIPEHVETRPLLNPDKPGIEQGRLEMWVDMFPMDVPSPGPAIDISPRKPKRYELRVIIWNTDEVILEDDDYFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFVFPFDYLMAEEKIVISKKESLFSWDETEYKIPARLTMQVWDADHFSADDFLGAIELDLNRFPRGAKTAKQCSIDMVLNEQELPTISIFKQKRVKGWWPFVARDENDDLELTGK------VEAELHLMTAEEAEKSPVGLGRNEPDPLEKPNRPDTSLMWFMNPLKSLRYFIWHNYRWLILKTLGLMLLLLLLGLFLYSIPG----YLVKKLLG 1872          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSAN-IYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEYFSPSTGSDNFGSDA 529
            M+L V LK +      GD+  K+ FR +   S  L+   +   F + F WP+A K+D N++L +  YN ++V  ++L+G  ++    ++ E  + V + L+D+        ++ EI Y  P  GS    SD 
Sbjct:    1 MALVVYLKTVTELRGKGDRIAKVSFRGLSFYSRVLENCEDEARFEEAFRWPVASKVDGNEMLEIHIYNYSKVFTNRLIGTFRMVLQKVVEEGHLEVSDTLIDDNNTAIQTSISIEIRY-QPMDGSVRVWSDG 131          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSS-----KIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYA---------------------KVASEKEPTPENQYVH-SMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGY--NRECFSGKM---PPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENK---LRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            I+P + +  DFQISVT++E R L G N++P+  V  G +K+ T +K  TN P+YNE+F FD  +    + + I+K+  +   N      + +G V+G F +D  +VY+   H F+ KWA L DP   T+G KGYVK DI+V+  GD  K P   +  +  +IE NLL+P  V    R+     + IY+AE LP MNT+I++N+K A  GE K L D YV+V FAG  G+T V    Y P WN+QI+FTE+FPP   R+++ +RD+D V D  + T FIDL+KI   G K   GFLPT GP+W+N+YG+ R++T   L+   Q  N+ L EGV++R RL++++       SS        V V     +S+  AGK E + LFG   E T+I+  +G   KP+ FE++IG  G+ +DD                       + +S++E T + + V  S T        D  YFH+PY  +KPC+++ +  +D R R++  NII+ +  +L E +     +   EK    RR L+  + +L       +      +  + KT LD +  +    +LE M  + + +  ++K+  V +K ++    ++ L     +PQ+ +PDI+I+MI    R+AYAR+ +++I++S++  E G  CG + T++ K L          + +QA+ ++YLWLGL R  + +  GLP G+  N+      M   PP  + Y  + +FQLRV+L+ AR++  +D +GLSDPFAR+  S H   + I  +T  P WD+ L+ DN+        L+  PP +V+EI+D D+    +F+GR F +P   +  + Y   +    L+++ +YRG   AGE+LAAF+L+++    K      LP +               G  D ++   L +P  IRP LS +R E+L WG+R L+R+ +                  V++P++ I+ AG  I+S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+T+L
Sbjct:  162 IEPGAGRPMDFQISVTVIECRQLVGLNMDPVVCVEIGDEKKYTSMKESTNCPYYNEYFVFDFHLPPDVIFDKILKLSVIHSKN-----LLRSGTVVGTFKMDVGTVYSQADHQFYHKWAILCDPDDITAGCKGYVKCDIAVVAKGDNIKTPHKANETDEDDIEGNLLLPEGVP-AERQWARFYLKIYRAEGLPKMNTSIMANVKKAFIGENKDLIDPYVQVQFAGQKGKTSVQKSCYEPIWNEQIVFTEQFPPLCKRMKVQIRDSDKVNDVALGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRSYT---LMDEYQDLNEGLGEGVSFRARLLVSLAVEILDTSSPEVMCSTEVQVEGVPNISDNAAGKIEEFFLFGAFLEATMIDRKIGD--KPINFEVTIGNYGSEVDDTPTKPKSKKSKKGDGDDEESELIQGSSDEEVTDDGELVSVSTTPPMKPVITDRNYFHLPYFERKPCIYIKSWWQDQRRRLYNANIIDNIADKLEEGLNDVQEIFKTEKAFPERR-LRGVLEDLSHGCSNFLELANKDQNQSGKTKLDRERLKSCMRELENMSQQAKTMRTQVKKKTVKDKFKQAQIFLQKLRFLADEPQHSVPDIYIWMISNGKRIAYARVPSKDILYSNVEEETGKDCGKVKTIFFK-LPGKKGFGPAGWTVQAKTEMYLWLGLNRQRKDFLSGLPNGFEENKAVKGPGMQSAPPISLIYTMKQIFQLRVHLYQARSLFAADSTGLSDPFARVFFSTHSQVTEILNETLCPTWDQLLVFDNVELYGEACELRDDPPIIVIEIYDQDTVGKADFMGRTFAKPITKMSDEHYGPPRFPPQLEYYQVYRGNCTAGEMLAAFELLQIGPGGK----ADLPPID--------------GPTDMDRGPILPVPIGIRPVLSKYRIEVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGIQSALIQNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVTSL 1145          

Query: 4352 ELENVKDFGGFHDPFKSFSLYRGKQEEDDD-NFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAP-IDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC--DPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            ELEN  +F  F D   +F+LYRGK  +DD+ N  + DR  G FKG++C+Y +   D    +   +                                     + +++N+   +P++ +VRVY+I+A +LHP+D+NGK+DPYI +KLG  E++D+ENYI K LNPVFGK  ++E TFP +S L V +YDWD +  DDLIGET IDLENR+ + H+ +CGI  SY  HGY  W+D   PT IL  LC++  +  P Y     RV + +R +   T IED++G + ++ E LAL VL+HW ++   G KLVPE++ETRPL  P+KPGI+QG +EMWVDM+P     P P +DI+PRK   +ELR  +  T++V L + + FT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWRF+Y FDYL AE+ IV ++K S++  DE EYK P  LN+QV D+    +D  +G  +  L++FP+ AK  + C  D     +     N+F+ K+++GWWP +   ++++ +          VE E+ L+T EEAE +PVG GR EP PLE P RPD + L FL P   IK+ +    KW++IKI V+ + L ++ LF+Y+ PG     +V K+ G
Sbjct: 1236 ELEN--EFEHFEDWLHTFNLYRGKSGDDDEQNASDEDRLIGKFKGSLCMYKVPMTDDMGREMGIDS-----------------------------------NMGMFQNIPHNDPINILVRVYVIRATDLHPADINGKADPYIAIKLGKTEIKDKENYISKQLNPVFGKSFDIEATFPMDSSLTVSVYDWDLVGTDDLIGETKIDLENRYYTKHRATCGITASYAIHGYNVWRDPMKPTHILAKLCKDGKLDPPQYGP-GGRVKVANRVYTGPTEIEDENGLKKQTDEHLALAVLNHWEDMPRVGCKLVPEHVETRPLLNPDKPGIEQGRIEMWVDMFPKDMPAPGPALDISPRKPKKFELRVIIWNTDEVVLEDDDIFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFIYPFDYLMAEEKIVISKKESMFSWDETEYKIPARLNIQVWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTIDMVLNEQEMPMVNIFKQKRIKGWWPFVARDENDELEITGK------VEAELHLMTGEEAEKSPVGEGRNEPEPLEKPNRPDTTLLWFLMPLKAIKHLVCNSYKWLIIKIVVVLLLLAMLGLFLYSMPG----YMVKKLLG 1819          

Query:  761 ISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGD-KPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIA----IKTSYQPDSSKIGVDVRPCNPVSNTVAGK---------------------------REMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEK-------EPTPENQYVHSMTQSRFAYT-------------YDNK-YFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRS--NVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGK---MPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLV 3712
            IS+ I EAR L G NI+P   +  G +K+ + +K  TN+PFYNE+F FD    +    + +IK+       +V+  +I     +G F ID  +VY   GH F  KWA LIDP   ++G KG++K DI V   GD  P+     D EE   IE N L+P    +  R      V +Y+AE LP MN++I++N+  A   +  AL D YV VSF    GRT        P WN+Q++F E FPP   RL+I V D   + D  I T +IDL +I       ++GFLPT+GP+WIN+YG+ R  T   L+  +Q  N+ + EGV+YRGRL I     I T      S   + +   +      AGK                            E ++LFG ++E T+I+  +G   KP++FE +IG  GN +D  A  A++K        P  E      + + + A +             + N+ Y+++P   +KPC+ +    ED   R+   N+++++    + +   T++    E                I S+EK V    +C      TMLD K   L + +LE M +++     E KR    + E ++E   L + +   + +PQ+ LPDIF++M+  N R+AYARI AR +++S    EKG  CG ++T++LK       K   ++ +QA++ +YLWLG   +       LPEG+     S +     P+ + Y D   FQLR +++ AR +I +D++GLSDPFAR+    H   + I  QT +P W++ L++D +  +     L   PP + +E++D D+    E+LG     P V +  + YT   L +  ++ G+L+ G+IL AF+L+E+    K      LP                Y + + +   +P +IRP L  +R E+L WG+R+L++++                +  V++P++ I+ AG  + S  I  +   PNF   +   ++ LP      PP+ I   +   FG   +VGN  I NL+
Sbjct:   38 ISINITEARQLVGENIDPSVVIEIGDEKKQSSVKEGTNAPFYNEYFVFDFFAHQEIFFDKVIKL-------SVMHSKIMKSYCIGTFKIDVGTVYNQPGHQFTNKWAALIDPNDISTGVKGHLKCDICVTGKGDVSPRSQKFSDAEEQ--IEKNPLVPEGFPSM-RPWARYYVKVYRAEGLPRMNSSIMANVTKAFVSDNTALIDPYVVVSFFSQVGRTSTQKSTADPVWNEQVVFKEMFPPLCRRLKIQVLDEGSMNDVAIGTHYIDLCRIS-NDQDGDKGFLPTFGPAWINIYGSARNST---LVDDNQEMNEGIGEGVSYRGRLYIQLAVEILTGGAESKSMFSLKLPSKDAKGGKTAGKDPKAGTGGADTSFIVGNLVFVKVSEENMENFILFGAMFEATMIDRRIGD--KPISFEFTIGNCGNFIDGAAPPAAKKRGERGFDHPGQEGAMTTPLLEGQAALSCKSTTRPEKPHTGHGNRVYYYLPISTQKPCIHVQCSWEDRTYRLHHSNMLDRI----AFLFVSTAYYCGQE---------------FIASVEKKVK--DNCL-----TMLDKKRLTLCKQELESM-IEVAGTITEPKRKVLTIKEMLQESRKLTQKIRFLVEEPQHTLPDIFVWMLSNNKRLAYARIPARNLLYSENVVEKGKDCGKISTLFLKPPG----KRGATWAVQAKVDVYLWLGKCTESSNMLKNLPEGFEIHGVSSEESGGAPEIVLYKDHHEFQLRAHMYQARGLIAADNTGLSDPFARVSFQSHTHVTAIINQTLTPTWNQMLMMDKLSLHGMLTELAQEPPLITIEVYDDDALGKPEYLGSTVAVPVVKLAEEPYTAPSLHYSPLFCGSLSGGDILGAFELIEVPKSGK----HSLPP---------------YDDPEGSIYPVPSYIRPVLRKYRIEVLFWGLRELKKVQ----------------LLTVDRPQVFIECAGKGVSSSVIQSYKSNPNFSMIVDAFEVELPEDEYLHPPLTITVVDWRAFGRSTLVGNHVINNLI 997          

Query: 4691 VDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVT 6217
            V+ ++RVYI+ A NLHP+D +GK+DPYI++KLG   ++DR+NYIPK LNPVFG+  E++ +FP+ES L + IYD+D +  DDLIGET IDLENR+ S H+  CGI   Y   GY  W+D   PT +L  LC+++ +  P +     R+ I ++ +  +T+  D+D   ++S E LAL+VLH W E+   G KLVPE+IETR LY+ +KPG+ QG ++MWVD++P     P  P+DI+PRK  GYELR  +  TE V L + NF T +++ DI+VK W+K  + D Q+TDVHY SL+G+G FNWRFV+ F YL AE  +V +++ +++ +D+ E K P  L MQV D   + SD  +G  +  L  FP+ AK  + C    L E+    ++F+ K+ +GWWP I + +               VE E  LVTAEEAE NPVG  R EP PLE P RPD +F  F+NP+    + I    K  +I   ++ +  L +AL  Y  PG++SN IV+
Sbjct: 1225 VNVLIRVYIVSASNLHPADPDGKADPYIVLKLGKTVIKDRDNYIPKQLNPVFGRSFEIQASFPKESLLKILIYDYDVIGGDDLIGETQIDLENRFYSRHRAMCGIPSEYAIDGYNAWRDCIKPTDLLIKLCKDNRLDSPRF--TPGRITIGEKVYTGKTVFADED-QMVESYEHLALKVLHRWEEMPGVGCKLVPEHIETRALYIKDKPGLDQGQVQMWVDIFPMDMPHPGPPVDISPRKPKGYELRIIIWNTEDVILEDTNFITGQQSSDIYVKGWLKGLEDDGQETDVHYNSLTGEGNFNWRFVFPFHYLPAEKLVVVSKRENIFSLDKTEQKLPAVLVMQVWDFERLSSDDFLGSVELDLHGFPRGAKTAKDCKMEMLKESNDNISIFQQKRSKGWWPFIKSEELTGK-----------VEAEFHLVTAEEAEKNPVGRARKEPEPLEKPNRPDTTFSWFVNPFKCFFHLIWKNYKKYIIIALLLLILALFLALLFYTLPGALSNKIVS 1722          

Query: 4253 KELFLKEEPDNLRMESEY-VTDNSWIERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYD----KLTDRVDIDDRSFFAETMIEDDDGSQ---IKSLEPLALEVLHHWHEI----VPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCD-PFQLSEACAKFNLFRNKKVRGWWPLI----------------------------------YNPKXXXXXXXXXXXXXXCVELEME--LVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVT 6217
            KE+  KEE D + +E E        I  + +Y  ELEN  +F  F D   +F +Y+GK   +D++ ++ DR  G +KG+  IY I  E+ E+ +D                                         ++ + +   +P+  + RVY++KA NL P+D NGK+DPY++VK+G +++  +E YIPK L+PVFG+  EL V+FP E+ L + I+D D +  DD+IGET IDLENR+ S H+  CG+   Y   GY KW+D R P+ IL  LC ++ +P P Y     K+ +++       F E +++ +  ++    +  E  AL VL  W E+    V    LVPE++E R L  PEKPG+ QG L MW+DM+P     P P++I PR  + YELR  +  T+ V L +VN FT E + DI+VK W+K  D + Q+TDVH+ SL+G+G FNWRFV++FDYL  E  IVY +K S++ ++E E++    L +QV D   I S+  +G  + RL+   + AK    C       +A  +F++FR+K+++GWWPLI                                    P+D    +  G       ++E E  LVTAEEAE NPVG  R EP PL+ P RP  SF  F+NP  T  +FI  + K  +I + ++ +  L + L +Y  P  IS  IV+
Sbjct: 1228 KEVKYKEEDDAVVVEIEPPAPKRKKISTLKLYKSELEN--EFSQFMDWLHTFPIYKGKANLEDEDDDDSDRIMGKYKGSFLIYPISSEEQEEEEDI--------------------------------------DFQITRGIPKNSPIKVLTRVYVVKATNLAPADPNGKADPYVVVKIGQQQLDSKERYIPKQLHPVFGEVFELTVSFPLETELNIIIFDHDLVGSDDMIGETRIDLENRFYSRHRAGCGLALYYDKDGYNKWRDSRKPSAILADLCRKNGIPSPEYRDTEVKVLNKIFKIPNEAFPEELLKKNKKTEEDYAEMDEHRALSVLQRWAEMREFTVGACPLVPEHVEVRSLLNPEKPGLPQGYLHMWIDMFPVDVPPPPPVNIKPRLPVSYELRVIIWNTDDVVLDDVNPFTGEPSSDIYVKGWIKGLDDEKQETDVHFNSLTGEGNFNWRFVFHFDYLPTEKEIVYKKKESIFSLEESEFRQHAVLVLQVWDYDRIGSNDFLGSIELRLNDMVRAAKSSELCSVKMAKDKASPRFSIFRSKRMKGWWPLIKLKSQEDIEREEREREMEKKNKKKKKKKQSKRGKMKPEDLQFVDSTGNTFLLMGKVEAEFQLVTAEEAEKNPVGKARKEPEPLDKPNRPKTSFNWFVNPMKTFVFFIWKKYKKYIIVLVILAILALFLFLILYTLPTHISQLIVS 1892          

Query:  713 LPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDK---PKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAI--------------------------KTSYQPDSSK-----------------------------IGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVAS---------------------EKEPTPENQYVHSMTQSRFAY--TYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGK---------MPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTR 2959
            L KH    + K++ FQ++V ++EA+ L G NINP   +  G +K+ T  +  TN PFYNE F F+   ++  + + +I+I  + K         F    +G F ID  +VY    H F++KWAP+ DPK   SG KGYVK  +SV+  GD       P A    +N +IE NLL+P  ++   R   +  + IY+AEDLP MN   + +    + G+ K   D YV+V+FAG  G T VV+   +P+WN+QI F E+FPP   R+++ + D+  + D  ++T F+DLQ+I    +    GF PT+GPSW+NLYG+P+  T   +    Q  N+ L++G+ YRGR+ +++                          K +++  S K                             + V+V   +P+     G++E +LLF   +E T+I+  +G   K +TFE+SIG  G   D   K                        E+E         S+T  R A    YD  +  I    +KPC+++    EDH  R    N + K+   L   I +   L+   ++  A+  L   ++  + + ++  S +   R  A+   LD      I+ ++  +  +   +   + R  V +K+ +   ++K +     +PQ  LPD+F++M+    RVAYARI A  ++ S +  E+G  CG ++T+Y+K     L +      I A+L++Y+WLG+ +  +     LP  + R  + G          MPP  +   D   FQLR +++ AR +I +DD+GLSDPF +++ S     + + T+ +
Sbjct:  214 LSKHELAAAPKVKSFQVNVNVIEAQNLVGVNINPAVYITVGHEKKRTATQKSTNCPFYNENFMFEFQETQDVLFDKVIEISVVHKKTLA-----FLMTRIGTFKIDISTVYQQPDHRFYQKWAPITDPKDTRSGVKGYVKCTLSVMMKGDSMNMASLPPA--TSQNEDIERNLLLPKRMA-AERPWAKFLLKIYRAEDLPSMNAGFLGSFSKMM-GDKKVFIDPYVQVTFAGQQGETSVVSNTNAPEWNEQISFIEQFPPLARRIKVQILDDSNMGDVAVATHFLDLQQI---SNPNRNGFNPTFGPSWVNLYGSPQNSTLRDI---HQDLNEGLSDGIFYRGRVQLSLSVEIYSSPTTAVIENKSSLSIKSPLSKLTFKRKSRKSREKSKESAGAQAASGPAEESEASEVPEAVTVEVEEIHPLPENFVGEKEEFLLFASFFEVTMIDPSIG--SKFVTFELSIGNYGKTADVVVKSKKSGSREDLSEDRQGLLESDDELEREEPAAGPLDKSVTAPRRAQPTEYDGSFSCISLLREKPCIYVWNYFEDHTFRYHNCNWLSKMADRLEYGIDEVEMLLKRPRS-NAKERLMEVLLEFVSTCKQYSSSLDRKR-QARPNPLDKHRSTFIKRNIIILAKQALRVRRRVTRRTVRDKLADVRRILKRIHFLTKEPQSTLPDVFLWMMSGGKRVAYARIPAHTVLFSLVEEERGKDCGKVSTIYMKTPGGPLGE------IFAKLEVYMWLGVTKYSKNCVTSLPAEF-RPVYEGATFGTPLPPNMPPTKLAVEDSRYFQLRAHIYQARGIIAADDNGLSDPFTKVVFSTQCQVTQVTTKKQ 1026          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEYFSPSTGSDNFGSDAF 532
            MS++V LK +       D+ ++L FRD   K+  L+      F + F WP   K+ K+++L +  YN++R+  ++LLG L ++  +++    + +RE L D    +TDI V  ++ Y      +  +  + F
Sbjct:    1 MSITVYLKTIYNLPGKYDRKVELSFRDFTHKTKILQCENVAIFKENFRWPHYGKIQKDEVLTISVYNSSRMFSNRLLGKLVVSLQHVVTAGRLVLREPLTDSNYSLTDIYVELDVRYHPLQGAAGEWSGEDF 132          

Query: 3347 IPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGS-AINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKE 4048
            IPE +RP L  FR E+L WG+R L+R+                 +F V +P++ ++ +G  IES +I  +   PNF++ +   D+    + +F                   + NC+I ++V  ++ +     + + +T +  ++V S++L             G   +D    IN L           VTAP+    +K + +  +  E E  DWW++YYA++ +L      KE
Sbjct: 1060 IPEGVRPVLKKFRIEVLYWGLRDLKRV----------------NLFEVEKPQVRMECSGQLIESGEIESYKQDPNFKEVVKHFDVVRNDAVKF-------------------MTNCSIMHVV--HKTNWPRAKKPVKRTPL--QTVVSMDL------------RGLPLKDTKIPINPLN---------LVTAPLKAVTKKEEELEEEEPEKEELDWWSKYYASLAELEKEVKYKE 1234          

Query: 4700 VVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGS-QIKSLEP-LALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAED-CIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKF-NLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPM---PLEAPMRPDGSFLSFLNPWNTIKYFIKY 6109
            +VRVYII+A NL P D NGK DPY+ + LG K V D +NYIP TL PVFGK  EL  + P E  L + +YD+D L+KD+ IGET IDLENR+LS +    G+  SY   G  +W+D   PT +L+ LC+  N  LPIY +  DRV      + A  + E    S  +  LE  LAL VL         + LVPE++ETRPLY P +P I+QG L+MWVD++P     P  P +ITPRKA  + LRC +  T  V L +V+  T E+  DI+VK WM   + + QKTDVHY+SL G+G FNWRF++ F YL AE  C +  ++  + +D+ E K P  + +Q+ D+     D  +G  +  L+   +PAK    C    LS    K  +LF  K V+GWWP + + + E             VE+ +E+V+ +E +  P GLGR EP     LE P RP+ SFL F +P+ T+K FI Y
Sbjct: 1489 LVRVYIIQAFNLQPKDANGKCDPYVKITLGKKSVNDHDNYIPCTLEPVFGKMFELTCSLPLEKDLKIMLYDYDMLSKDEKIGETVIDLENRFLSRYGARSGLPQSYCVSGVNQWRDQLKPTQLLQRLCQRRNYKLPIYKQ--DRVYFRGHEYTAADLDEAKQPSPHLGPLEERLALLVLRR-------QGLVPEHVETRPLYSPLQPEIEQGRLQMWVDIFPKSLGPPGPPFNITPRKAKKFFLRCIIWNTSDVILDDVS-VTGERMSDIYVKGWMHGHEGNKQKTDVHYRSLGGEGNFNWRFLFPFHYLPAEQLCTIDKKEHFWSLDKAESKIPPKITIQIWDNDKFSFDDYLGCLEMDLNHMLRPAKSPEKCGLELLSRTQDKLVSLFEQKTVKGWWPCVCDKEGEKILAGK-------VEMSLEIVSEQEQDERPAGLGRDEPNMNPHLEDPQRPETSFLWFSSPYKTLK-FINY 1948          

Query:  734 QSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTN--EGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEG--KALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVK-DETISTIFIDLQKIMYTGSKEEE----GFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQA---RRYLKTSIINLIPS-IEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKR---SNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGY 2740
            + LK+   Q+ V I+E R L G NI P+ +V  G Q + T IK + N+PF++E F  +   +  ++ +  I I          ++ + T  V+GEF +      +     H+  RKW  L DP   ++G +GY+K  + VL AGD+P     +  +E  +IEANLL P  ++    +     + +Y+AEDLP M+   +  +K  +  +   K L D  VE++FA       V              F++ FP    ++RI + D D    ++ I T  + + KI   G + E     GFLPT+GP ++NLYG+ R F  T      +  N    EGVAYRGR+++ + T       +   D++P + +      ++  Y LF   Y  T + +        + FE+SIG  GN  D      +            S TQ   A      Y+++P+KN KP + + ++ ED  PR      IE L   LS +    S+L  ++  +Q+   +  L+ +++ L+   I      +         T LD   +RL +++L+    +++  AL LK    + +   + +     + L     +PQ  LPDI I+M+Q + RVAY RI A E++ S      G  CG + TV++K              I AQL++ +W GL  D++ +
Sbjct:  168 KHLKLYFIQVRVRIIEGRQLPGVNIKPVVKVTVGGQTKRTRIK-KGNNPFFDETFFLNFFETPADLFDEPIFITVFD------SKSLRTDSVIGEFKVMCACFLSVLFGRHAILRKWLLLADPDDLSAGARGYLKASMFVLAAGDEPPTDKKEGVQEKEDIEANLLRPAGLT---LRGANFTLKVYRAEDLPQMDDAFMDGMKQFLGFDSNRKNLVDPLVEINFAVLLTHVHVP-------------FSQ-FPSMCEKMRIRILDWDRASHNDVIGTTHLCMSKICAPGGEIEVDDSLGFLPTFGPCFVNLYGSLREF--TAFSDPHEALNLGKGEGVAYRGRVLLELNTKLCERVEQRVEDIQPDDLLVVEKFMRKRKYSLFAAFYSATHLQD----VDDAIQFEVSIGNYGNKFDCTCLPLA------------STTQYSRAVFDGCHYYYLPWKNVKPVVVLSSEWEDISPR------IEALNMLLSIVDHLESNLKLVQLELQSGGDQDDLEQTVVKLLDDVIADCSEELPEFDNWPCVTPLDKSLRRLRKVNLK----QIEQAALTLKHGPETELSSVLEQAEDWAQRLRSLAEEPQNSLPDIVIWMLQGDRRVAYHRIPAHEVLFSQGY--CGKHCGQLQTVFMKYPQGG----GGCTKIPAQLRVKVWFGLAADVKHF 794          

Query: 2822 SMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNI-IFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLP--TVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGD-STIVKEVIEKLSESESD-EEVTGF 4099
            +++ LR YL+ AR+++  D    SDPFA +       K+       +P WD+TLI   + IF  A +V + SPPN+VVE++D D+   +EF+GR  CQP +       ++ +L W+ I +    AGE+LAAF L+  D    K ++  +P   V ++  +            + N   +P  I+P L     EIL WG+R L                K F +  V  P + ++  G  ++S  I +    PNF+ N +F+D+RLP    + PP+ I   ++  FG K +VG C I +L + ++C                                       E+++    NE  D   + P  DV       ++  +P++   ++ E  DWW+++YA+ G+     + +++ ++ L   E + E+V GF
Sbjct: 1065 TLYHLRCYLYQARDLLAMDKDSFSDPFAIVSFLHQSQKTVTVRNNLNPTWDQTLIFYELEIFGDA-EVTEKSPPNIVVELYDQDTYGTDEFMGRSVCQPSL------VSSPRLAWYPILKNGKEAGELLAAFQLIRRD----KPSIHRIPGQEVGNVSVLYDTDLPCPPPLREPNIFMVPLNIKPVLQRTAIEILAWGLRNL----------------KSFQLASVTSPSLQVECGGRMVQSCVIRNTKKNPNFDINTLFIDVRLPREELYMPPLVIKVIDNRQFGRKPVVGQCTIRSL-EEFRCQP-------------------------------------ESQEAEPPNEEFDEVPQTPRDDVLI----DIDDKEPLISGQDD-EFMDWWSKFYASTGETKKCGSYLEKGLDTLQVYERELEKVEGF 1425          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSY----QPD---SSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKV--------------------------ASEKEPTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKM--KVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYM-IQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFS-GKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIK-KMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDY-YQCDQVD----NFREIDKTTIDE-RSVKSLNLFNAGNDTEGILNEGFENEDGSAIN---------ELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESA--DWWTRYYATIGDLGDSTIVKEVIEKLSESESDEEVTGFVLXXXXXXXXXXXXXXXXXXXXXXXPXXXXXXXXXXXXXXXXXXNPFQPSTKELFLKEEPDNLRMESEYVTDNSWIERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIY 4498
            +DP + K + +Q+SV I+EAR L G N++P+  V  G++K+ T  K  TN P+YNE+F FD       M + IIK+  +   N      I +G ++G F +D  +VY+   H F+ KWA L DP   T+G KGYV  DI+V+  GD  K P    + +  +IE NLL+P  +    R+     V IY+AE LP MNT I++N+K A+ G+ + L D YV+VSFAG  G+T V   +Y P WN+Q++FTE FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT+GP+W+N+YG+ R +T   L+   Q  N  L EGV++R RL++ I         P+   +++I V+  P +    + +GK E + LFG   E T+I+  +  + K ++FE+SIG  GN LD   K                            ++     ++    S T S    T D +YFH+PY  +KPC+++ +   D R R++  NII+K+  +L E I      + +E+    RR L+ ++  +     + ++          +T LD    ++   +LE+M  + KL      +  +    +    +TL +     MA PQ  +PDIFI+M + +  RVAYARI A++I++S +  E G  CG + T++L RL    +  +  + +QA+L+ YLWLGL +  + +  GLP G+  +      +PP  ++Y   S F+LR +++ AR++  +D +GLSDPFAR+I S H   + +F +T  P WD+ L   ++     P  L+  PP VV+E+FD D+    EF+GR   +P V I  + Y   +    L ++ IYRG + AGE+LA+F+L++            +P   + K    S +ND   G +    + +P+ IRP L+ +R E+L WG+R L+R+++                  V++P++ I+ AG  I+S  I D+   PNF   + F ++ LP +  F PP+ I   +   FG   +VG+  +T+L  + +     D      RE + TT +  R V+ L      +  E ++    E   G  +N          L  +   +  P  T    G   K K   P+  E + +  DWW++Y+A+I  L + + ++   E   E  + E V G       ++  +     +                              + + K+  LK++P +L++E            + +Y  ELE   +F  F D   +F+LYRGK  ++DD  +  +R  G FKG+ C+Y
Sbjct:    8 VDPTAGKPQSYQVSVMIIEARQLVGLNMDPVVIVEVGEEKKQTSQKESTNCPYYNEYFVFDFHTPPNMMFDKIIKLSVIHSKN-----LIRSGTLVGTFKLDVGTVYSQPDHRFYHKWAVLTDPDDITAGIKGYVNCDIAVVGKGDNIKTPHKSVDNDADSIEGNLLLPEGIP-ADRQWARFFVRIYKAEGLPKMNTAIVANVKKALMGQERDLVDPYVQVSFAGQKGKTSVQRSSYEPVWNEQVVFTELFPPLCRRMKLQIRDSDKVNDTAIGTHFIDLKKICNDGDK---GFLPTFGPAWVNMYGSTRNYT---LMDEHQELNDGLGEGVSFRARLLLGISMEILDITSPELSTNTEISVESIP-HVADESCSGKMEEFFLFGAFLEATMIDRKI--SDKLISFEISIGNYGNSLDGLNKSNILDRSDDEDEYDEGDEDDETELLNDETDDAEMDDDTSGSSTTPSYKPETNDRQYFHMPYYEQKPCVYVRSAWHDQRRRLYNSNIIDKIADKLEEGISDVLETMKMERPHPERR-LRGALEEMSVGCSRFLTLANKDPSAFGRTRLDRDRLKICMRELEQMGPQAKLGRARTRIHTAPHSTRHTTSSTL-RSTAALMAAPQDSIPDIFIWMLVNKTKRVAYARIPAKDILYSIVEEETGKDCGKVKTLFL-RLPGKRVFGSGGWTMQAKLEAYLWLGLNKQRKDFLTGLPSGFEEKKIGVTGVPPSVLNYHKRSQFELRAHMYQARSLFAADSTGLSDPFARVIFSTHCKSTEVFQETLCPTWDQLLQFQDVYMYGEPRELRDDPPMVVIEVFDQDTVGKAEFIGRALAKPVVKISTEPYEPPRFPPMLDYYQIYRGPVTAGELLASFELLQ------------VPPADNCKFPPVSGLNDTDRGPI----IPVPKGIRPVLAKYRIEVLFWGLRDLKRVQLQS----------------VDRPRVDIECAGKGIQSVVIADFNKNPNFSHLVKFFEVDLPENELFHPPLNIRVVDCRAFGRYILVGSQTVTSLRKFIFHTTGPDMGRQGSREYNNTTCEPIRMVRPLCTSRRYSAIEAVIA---EMPSGPIVNLTVLLSLDSWLNGLLSFEGEPGATQ---GKKSKKKKTEPEDAERDESVLDWWSKYFASIEMLQEQSRLQTPGEDAVEGATAEPVQGLSAICSILSKYNKNSSAESPRKALQF---------------------HKAADKDKQLKKKP-HLQVEE-----------LKVYDKELE--AEFDNFEDWLHTFNLYRGKTSDEDDILDE-ERVVGRFKGSTCVY 1232          

Query: 4661 LYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC--DPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            +++ +   +P++ +VRVYI++A +LHP+D+NGK+DPYI++KLG  EV+D ENYI K LNP+FGK  ++E TFP ES L VQ+ DWD +  DDLIGET IDLE+R+ S H+ +CGI   Y  HGY  W+D   PT IL  LC+++ V  P Y     RV + +R F   T +EDD G + ++ E LAL+VLH W EI   G KLVPE++ETRPL  P+K GI+QG LEMWVDM+P     P  P+DI+PRK   YELR  +  T++V L +  F T EK  DI+V+ W+K    D Q TDVHY SL+G+G FNWRF+Y FDYL AE+ IV ++K S++  DE EYK P  L +QV D+    +D  +G  +  L++FP+ AK  + C  +  ++  +    ++F+ K+V+GWWP +   ++++ +          VE E+ L+TAEEAE NP GLGR EP PLE P RPD SF+ FLNP  +IKY I +R KWI+IK+ V  + L+++ LFIYN PG     +V K+ G
Sbjct: 1252 MFQGIPTNDPINVLVRVYIVRATDLHPADINGKADPYIVIKLGKTEVKDNENYISKQLNPIFGKSFDIEATFPMESMLTVQVMDWDLVGMDDLIGETKIDLESRYYSRHRATCGIAQQYAVHGYNTWRDPMKPTQILAKLCKDNKVDGPHYGP-GGRVKVANRIFNGPTEMEDDSGHKKQTEEHLALKVLHSWEEIARVGCKLVPEHVETRPLLHPDKTGIEQGRLEMWVDMFPKDMPHPGPPVDISPRKPKSYELRIIIWNTDEVILEDDAFMTGEKMSDIYVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFIYPFDYLVAEEKIVISKKESLFSWDETEYKIPARLTLQVWDADHFSADDFLGAIELDLNRFPRGAKSSKQCTLNMLKMDGSVPMISIFKLKRVKGWWPFVSRDENDEQELTGK------VEAELHLLTAEEAEKNPAGLGRNEPDPLEKPNRPDTSFIWFLNPLKSIKYVICHRYKWIIIKLVVALLMLVLLGLFIYNMPG----YMVKKLLG 1768          

Query:  710 KLPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAI------KTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAK-------------------------VASEKEPTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSN-----------VYEKMRECNTLVKLLEDKMADPQYGLPDIFIYM-IQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGY-NRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEM 3229
            K  + +DP + K + +Q+SV I+ A+ L G NI+PM  +  G  K+ T I+  TN P YNE+F FD   +   M + +IK   L+  +N  A R  +G  +G F +D  +VY+   H F+ KWA LIDP   T+  +GYV+ DI+V+  GD  K+       ++ ++E NL++P       R+     V IY+A  LP MNT I++N+K A+ G+ K L D YV+VSFAG  G+T V N +Y P WN+Q++ T+ FPP   R+++ +RD+D V D  I + FIDL KI   G K   GF+PT+GP+W+N+YG+ R +T   L+   Q  N  L EGV++R RL++ +      KTS + +++   V V     ++++V GK E + LFG   E T+I+  + +  K ++FE+SIG  GN +D   K                          A + + T E   + S T      T D +YFH+PY  +KPC+++ +   D R R++  NII+K+  +L E I      +  +K    RR        L  ++E++ SG +     A K   D        LD +++K++L+ L   ++ S            + + MR    L+  L   + DPQ+ +PD+FI+M + +  R+A+ARI A++I++++   E G  CG + T++LK L          + +QA+L++YLWLG  +    +  G+P G+  ++     +PP+ + Y   S F+LR +++ AR++  +D +GLSDPFAR+I S H   + +F +T  P WD+ L   ++     P  L+  PP VV+E++D ++    EF+GR   +P V I  + Y   +    L ++ IYRG L AGE+LA+F+L+++
Sbjct:  252 KPEQRVDPTAGKPQSYQVSVMIIRAQKLVGLNIDPMVILEVGDAKKKTRIEKSTNCPNYNEYFVFDFNTAPNTMFDTMIK---LTVVHNKDAIR--SGTPIGTFKLDVGTVYSQPDHRFYHKWATLIDPDDITADVRGYVQCDITVVGKGDNIKKSHKSIESDDDSLEGNLILPDGCKGE-RQWARFYVNIYKAVGLPKMNTAIVANVKKALMGQEKDLVDPYVQVSFAGQKGKTSVQNNSYEPVWNEQVVLTDIFPPLCRRMKLQIRDSDKVNDVAIGSHFIDLTKICNNGDK---GFMPTFGPAWVNMYGSTRNYT---LVDEHQELNDGLGEGVSFRARLLLQLTTELLDKTSPELNNT-TEVMVEDIPRINDSVLGKMEEFFLFGAFMEATMIDRSISE--KLISFEISIGNYGNSIDGLNKSNPQERSDDEDEDDDEDDEEETVLLTAQKAKGTDELSSMFSTTPPMKPETNDRQYFHMPYYEQKPCVYVESTWHDQRRRLYNSNIIDKIADKLDEGISDVKEAMKTDKPHPERR--------LRGALEEMSSGCERFCSLANK---DSSSIDCTDLDRKRLKMRLKELIYNIQHSFKTMLCMLFIQIINDMMRVMRNLLSALIACIKDPQHSIPDVFIWMLVNKTKRIAFARIPAKDILYANADEELGKDCGKVKTLFLK-LPGKRSFGPGGWAMQAKLEVYLWLGTNKQRNNFLNGMPTGFVEKKSIDPTVPPRVLTYSKRSQFELRAHMYQARSLFAADSTGLSDPFARVIFSTHCKSTEVFQETLCPTWDQLLEYQDVYMYGEPRELRDDPPMVVIEVYDQNTMGKSEFIGRALAKPVVKISTEPYEPPRFPPMLDYYQIYRGPLTAGELLASFELLQV 1112          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSAN-IYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEY 487
            M+L V+LK ++      D+  ++ FR +   +N  +   +   F + F WP+A  ++ ++ L ++ YN  ++   +L+G  ++    L+ +  + + E L+DE        V  E++Y
Sbjct:    1 MALVVHLKRVEKLRGKADRIARVTFRGLTFDTNVFENCEDEARFDKIFRWPLATAINGSETLEVQVYNHGKLLSKRLVGTFRMVLQQLVEQGQLELTETLLDENNASIMATVTLELQY 118          

Query: 4661 LYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC--DPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPG 6193
            +++ +   +P+  +VRVY+++A +LHP+D+NGK+DPYI+VKLG  EV+D+ENYI K LNPVFGK  ++E  FP +S L V IYDWD +  DDLIGET IDLENR  S H+ +CGI   Y  HGY  W+D   P+ IL  LC+E  V  P Y     RV + +R+F A T +ED++G +  + E +AL VLHHW EI    KL+PE+IETRPL  PEKPGI+QG +EMWVDM+PA    P  PIDI PRK    E+R  +  T+ V L + +  T EK+ DIFV+SW+K    D Q TDVHY S++G+G FNWRFV+ FDYL AE+ IV ++K SV+  DE EYK P  L +QV D+    +D  +G  +  L++FP+ AK  + C  D  +   +    ++F+ K+++GWWP     ++++ +          VE E+ L+T+EEAE +P GLGR EP PLE P RPD SF+ FL P  +IKY I +R KW+++KI +  + L ++ALF+YN PG
Sbjct:  477 MFQGIPSNDPIGVLVRVYVVRANDLHPADVNGKADPYIVVKLGKHEVKDKENYISKQLNPVFGKSFDIEAVFPMDSMLTVSIYDWDLVGTDDLIGETKIDLENRLYSKHRATCGISQRYSIHGYNMWRDPLKPSQILARLCKEVKVDPPQYSP-EGRVKVANRTFTAATEVEDENGQKKPTDEHMALTVLHHWEEIPGACKLIPEHIETRPLLHPEKPGIEQGRIEMWVDMFPADVPRPGPPIDIAPRKPKSLEMRVIIWNTDDVILEDDSLLTGEKSSDIFVRSWLKGQQEDKQDTDVHYNSVTGEGNFNWRFVFPFDYLVAEEKIVMSKKESVFSWDETEYKIPARLTLQVWDADHFSADDFLGAIELDLNRFPRGAKTSKLCSLDMLKTDGSVPMISIFKQKRIKGWWPFAARNENDELELTGK------VEAEIHLLTSEEAEKSPAGLGRNEPDPLEKPNRPDTSFMWFLTPLRSIKYLICHRYKWLIVKIVLALLLLAMLALFLYNMPG 984          

Query: 2750 LPEGY------NRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDM--------KTKKITVKGL--PTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLG------DSTIVKEVIEKLSESESDEEVTGF 4099
            LP GY      N    +  +PP  + Y ++ MFQLRV+++ AR++  +D +GLSDPF RII S H   + +  +T  P WD+ L+ D+I        L+  PP +V+E+FD D+    +F+GR   +P V +  ++Y   +    L ++ IYRG   AGE+LAAF+L+++          +T       L  P+ K      S   D  +G +    L +P  IRP LS +R E+L WG+R L+RI++V                 V++P++ ++ +G  ++S  I  +   PNF       ++ LP +    PP+ I   +   FG   +VG   +T+L  +         R   KT       K+ N+   G+  +  L        GS    +         P VTA         +P++ Q +E E  DWW++Y+ +I  L              ++EK+ + E + E   F
Sbjct:    1 LPNGYEQKKAKNSSPIAQALPPISLIYKEKQMFQLRVHMYQARSLFAADSTGLSDPFGRIIFSTHSQATEVIPETLCPTWDQMLVFDSIELYGEAQELRDDPPIIVIEVFDQDTVGKADFIGRALAKPVVKMSNEKYDAPRFPPQLDYYQIYRGNSTAGELLAAFELLQVATSPTHHHAPRTTAPRPATLIPPSGKGDLPPISGPTDTEHGTI----LPVPRGIRPILSKYRIEVLFWGLRDLKRIQLVT----------------VDRPRVDVECSGKSVQSVVIPSYKQNPNFSTLFKHFEVDLPDNELLHPPLNIRVVDCRAFGRYTLVGTHTVTSLRKFI-------LRAPSKT-------KAANIRTIGDPNDPRLPAS-----GSVCQSVC--------PQVTA--------HQPIIHQPDE-ELLDWWSKYFVSIETLNKRCKKKLKKKRSPILEKMFDKELEGEFDNF 420          

Query: 4340 MYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIY 4498
            M+  ELE   +F  F D   +FSLYRGK E+DD + E  DR  G FKG++C+Y
Sbjct:  408 MFDKELEG--EFDNFEDWLHTFSLYRGKIEDDDSSMEE-DRLVGRFKGSLCVY 457          

Query:  737 SLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYG---EGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDND-MVKDETISTIFIDLQKIMYTGSKEEE---------------------GFLPTYGPSWINLYGTPRTFT-----YTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAG-KREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSN--------VYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEK-GIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGY 2740
            S K  DFQ+ + ++EAR L GNNI P+ +V    Q + T I+ + N+PF++E F F+  +S  E+ + +I  + L       +  +     +G F +D  +VY    H+F RKW  L DP+  +SG KGY+KV + VL AGD+P    ++  EE  +IE NLL P  VS    +   + +  Y+AED+P M+  ++  +K  I+G     K L D Y+EVSFAG T  TK++ +N +P+WNQ I    RFP    RLRI + D D +  ++ + T F+ + +I   G  E E                     GFLPT+GP +INLYG+PR FT     Y +L       N    EGVAYRGR+++ + T  + D     V+  P + +       +R  Y L    Y  T++ E      +P+ FE+SIG  GN  D      +            S TQ   A       +++P+ N KP + + +  ED   R+   NI+   +R L   I +      +   +QAR  ++   ++ + +I+ +   ++ C     +     +   +  LD E  + +   LAL L+ +         V E + E +  ++ L +   +PQ  +PD+ ++M++ + RVA+ARI A E++HSS+ P   G  CG+  T+ LK   ++       + I  Q+++ +WL L  D + +
Sbjct:  205 SRKPRDFQVRIRVIEARQLPGNNIKPVVKVTVAGQSKRTRIR-KGNNPFFDETFFFNFHLSSAELFDELIYFKVLH------SHSLRADSEIGTFKLDVGTVYDEPRHTFQRKWLLLCDPEDLSSGAKGYLKVTLLVLGAGDEPPEDRSEAVEEREDIENNLLRPAGVS---LRGAFLTLRAYRAEDVPQMDDAVLDTVKQ-IFGFDSNKKNLVDPYLEVSFAGKTLCTKIIEKNANPEWNQAISLPIRFPSMCERLRITLYDWDRLTHNDAVGTAFLSMSQISCPGGDEPEAFITMRCLRLNLLRLIEDEGTGFLPTFGPCFINLYGSPREFTGFPDPYEEL-------NFGKGEGVAYRGRILVELTTKLE-DHINNKVEPIPSDDLLRVEKYLRRRRYNLCATFYSATMLRE----VNEPIQFEVSIGNYGNKYDVTCPPLA------------STTQYSRAVFDGCSSYYLPWGNIKPVVTLTSYWEDVGHRLEALNILMHTQRRLEVNIGR------VRATLQAREPVEAVAVSWLHAIDTL---IEDCSQALPEI---TERPNVTPLDREVWRARSATLALILRSAQRLREEATRVEETLSELDDWLERLTELTREPQNSIPDVVVWMLRGDRRVAFARIPAHEVMHSSLGPHACGKNCGITQTIVLKYPQDT-----HGFKIPGQVRVRIWLSLAADSKSF 860          

Query: 5027 GYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGI-QQGLLEMWVDMYPAGTAIPAP-IDITPRKAIG-YELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAED-CIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAK-----FNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPM---PLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILI 6130
            G  +W+D   P++IL+ +    + P PIY+   DR+ +  R +       +        L P+   +  H   ++    L+PE++ETR L    +PG+ QQG L MWVD++P     P P  DITPRKA   Y+LRC +  T+ V +++    T EK  DI+VK W+   D   QKTDVHY+SL G+G FNWR+++ F+Y+ AE+ C+V  ++  + +D+ E + P    +Q+ D+     D  +G     LS  P PAK    C    +     K      +LF  K V+GWWP I       ++E+  + I G VE+ +E++  +EAE  P GLGR EP     L+ P RP+ SFL F +P  T KY I  R KWI I
Sbjct:    2 GQNQWRDQMTPSMILEGVARAKSWPQPIYE--GDRLTLKGRDYLMSDF--EAKAPTNPHLGPVKERLALH---LLRSMGLIPEHVETRTLEHSIQPGLEQQGKLMMWVDVFPKNMGPPGPPFDITPRKAKKRYQLRCIIWNTKDV-ILDETSITGEKMSDIYVKGWIDGRDDAKQKTDVHYRSLGGEGNFNWRYIFPFEYVPAENICVVSRKEHFWSLDKTELRLPPKFTIQIWDNDKFSPDDYLGYLDLNLSHMPVPAKSAEKCSLEMVETPTGKKKHKTTSLFEQKNVKGWWPCI-------AEEDGKKIIAGKVEMTLEILADKEAEERPAGLGREEPNMNPKLDPPNRPETSFLWFTSPLKTFKYIIWRRYKWIFI 366          

Query: 4703 VRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLEN 4969
            + + +I    L  +D NG SDP++ + + DK+V  + N   KTL+PV+ +  ++ +    ++ ++  + DWDR   +D +G+ ++D+ +
Sbjct: 1136 LNIKLISGHGLKSADRNGYSDPFVHIFVNDKKVF-KSNIKKKTLDPVWNEDAKIPILSRSKNQVIFNVLDWDRAGDNDDLGQASLDVSS 1223          

Query:  761 ISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPK----SPTSGEKGYVKVDISVLCAGDKPK-RPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIG---VDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLD----DYAKVASEKEPTP------------------ENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAK--KTMLDVKYQRLIRLDLEKMKVKLQNLALELK-RSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGKM---PPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTT----AKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFR--EIDKTTIDERSVKSLNLFNAGN--DTEGILNEGFENEDGSAINELTDMK-EEKPNPDVTAPVPGTVEKVKPVLPQ--------------TEEMESADWWTRYYATIGDL--GDS 4033
            I + I EAR L G  I+P+  V  G QK++T IK QTN PFY+EFF FD  M  + + + I+  +      N+V+Q    G ++G F +D  +VY    H F R+WA L DP+    +  +G KGY +VDI+VL  GD  K +P   DN+++  IE NLL+P  V    R    + + IY+AE LP MN+ +++N+K A  GE + L + YVEV FAG+  RT V    Y P WN+Q++F+E FPP   R++I ++D+D V DE I T FIDL +I   G+    GF+PT+GP W NLYG+ R ++   L       N  L EGVA+RGRL+IA+   +   +S+ G   V+V P  P+S+T AGK E + LF   YE ++I+  +G   K ++FEMSIG  GN +D    D    A+  + T                   +N +++S+T      T D +Y+HIP+++ KPC  +    +DHR R++  N++ K+   L + +      + ++      R+L   +  LI    + ++ +KS    +   +T LD +  +L + ++E +    Q L    K  +++ + ++  N L++ L +   +PQ  +PD+FI+M+    RVAY+RI ++ I++S +  E+G   G M TV+L RL          + IQA+L I +WLGL +  + Y    P+GY     + K+   PP ++ Y ++  F LR +++ AR++IGSD SGLSD FAR+I +  ++ + +  +TRSP WD+TLI   ++     + +  +PP +VVEIFD D   D EF+GR   +P V +  + Y        L+W+ + RG   AGE+LAAF+L+++   T  +  +  P       +T                 +P  IRP +   R E+L WGVR+++RI +                  V++P++ ID+AG+ I+S  IT+    PNF++ + + D+ LP + ++ PP+ I   +   FG   +VG   + +L  Y Q  + +  R  +  K+ +D + +    L N  +   + G      E +D   I E+  M+ + +   D   P+      +                     ++ +S DWW+RYY T+ D   GDS
Sbjct:  262 IQIRIHEARQLAGTQIDPVCTVSVGNQKKSTTIKEQTNCPFYDEFFVFDFKMPPMVLFDKIVMFQ-FYTGRNLVSQ----GALIGSFKLDVGTVYAQPDHRFCRRWAVLTDPEETLGASGAGVKGYARVDITVLGKGDPAKEQPGIKDNDDD--IEGNLLLPDGVP-AERPKARVIIKIYRAEGLPKMNSGLMANVKKAFTGEVRDLVNPYVEVQFAGHRARTTVKKNTYEPKWNEQVVFSELFPPLCRRIKIQLKDSDSVTDEVIGTHFIDLSRISNDGAN---GFMPTFGPCWANLYGSTRDYS---LFDEHNDLNNGLGEGVAFRGRLLIAVHAEFGESASESGIRQVEVEPTAPISDTAAGKDEQFQLFACFYEASMIDRKVGD--KMVSFEMSIGNWGNSIDGQPIDEVSHATHIQHTSNTQHTQSTMGGDEDRRDGDNPFLYSLTPPVKPVTNDRQYYHIPWEDSKPCTHIKFMWQDHRRRLYNSNVLLKICERLEDGLTDCIERVKMDLP-NTFRWLSRVLSELINGCNQYLNLIKSMPTASHVGRTKLDKERLKLCQYEVESVCTSAQELKTSTKDDTHMKDNLKAANALLQRLLNIAVEPQDTIPDVFIWMLCGGKRVAYSRIPSQHIMYSLVEEERGKDSGRMQTVFL-RLPGKRGDGPKGWAIQAKLNIMIWLGLHKHKKDYLKDAPKGYQTPKNAHKLMAPPPNHLIYTEKQKFVLRAHVYQARSLIGSDASGLSDAFARVIFTHLVSDTRVIWETRSPTWDQTLIFQEVVLWGDVNEIAVNPPTIVVEIFDKDIGGDSEFIGRALARPIVKMACEPYEKPFFPPALEWFQVCRGEENAGEMLAAFELLQVTSGTCFLPSEVEPVNTPDGPITP----------------VPVGIRPVMKKHRIEVLFWGVREMKRINLT----------------TVDRPQVDIDLAGHVIQSTVITNAKKNPNFQNPVCYFDVELPENERYCPPLTIRVRDCRTFGRFTLVGTHVLNSLHRYLQTGEKEKERIEKAGKSCLDRKRL----LANGPSRPTSPGGGEVALEMDDAPPI-EMEQMELQARLITDTETPIAVVATDMHASTDHEKKKEKGDKDKKEDDDDEDSLDWWSRYYETLKDQEKGDS 1358          

Query: 4721 KAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIP-APIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC--DPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            KA+NLHPSD+NGK+DPY++V LG   VRDR+NY+ K LNP FG+C E E   P +S L V IYDWD +  DDLIGET +DLENR+ S H+ +CG+   Y   G+ KW+D   PT IL  LC+E  +  P Y   T RV +D++ F A   I ++ G   +S EP AL  L  +  +  G  LVPE++ETR L+ PEKPG++QG LEMWVDM+P     P AP+DITPRK   YELR  +  TE V L   N  T EK  DIF+K W++    D Q+TDVHY+SL+G+G FNWRF++ F Y KAE+ IV T+K S +  DE E K P  L++QV D+    +D  IG     L++ P+ AK  +SC  D  +   +  + + F+ K ++G+WP   N ++E+ +          VE E+EL+T EEAE  P G  R +P  LE P RPD +++  +NP   +K  I    +  LIK+ VI + L ++ LF Y+ PG      V K+FG
Sbjct: 1490 KALNLHPSDVNGKADPYLVVNLGKHRVRDRDNYVSKQLNPTFGRCFEFEAIIPMDSMLTVGIYDWDLVGSDDLIGETKVDLENRFYSRHRATCGLQDQYATFGFNKWRDPLRPTQILAKLCKEEGLDGPHYS--TGRVRVDNKVFVAAPQILEESGHWKQSDEPSALRCLKQFQTLKRGFTLVPEHVETRALFNPEKPGVEQGKLEMWVDMFPMDMPSPGAPVDITPRKPTSYELRVIIWNTEDVLLEEANMLTGEKCSDIFIKGWLEGLKDDKQQTDVHYRSLTGEGNFNWRFIFPFQYQKAEERIVITRKASFFSWDESEEKVPARLHLQVWDADAFSADDFIGDLCLDLTRMPRGAKTSKSCTLDLLKQDGSVPQVSFFKMKHMKGFWPFFVNTEEEEIELAGK------VEAELELLTQEEAEKKPAGRAREDPQALEKPNRPDVAWMMMMNPLRGLKAMIWNNYRMCLIKMLVIALLLALMGLFFYSMPG----YTVKKIFG 1984          

Query: 4352 ELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIY----DKLTDRVDIDDRSFFAETM--IEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAP-IDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKS-VYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC----DPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMP---LEAPMRPDGSFLSFLNPWNTIKYFIKYRLKW 6121
            ELE +++FGG  D   SFSLYRGK ++ DD+ E   +  G FKG   IY +   +  D D  E                                        ++ NL    P+D VVRVYI+ AI+L P D  G +DPY++V+LG K++ +++ Y P TLNP+FGK  EL+   P    L + + D+D LT+DD+IGET IDLE R L+ ++  CGI  +Y + G  +W+D++ P  +L+  CEE       Y    D   DR+ +  R +  +      + +       + LAL VL+         + +PE++ETR L  P +P I+QG +++WVD++P    +  P +DIT R+   YELR  V  T  V +++    T E+  DI+VK W++    D +KTDVHY+SL G G FNWR V+NF YL  E  +V  +K   + +D  E +    LNMQ+ D+     D  +G  +  L K P+P +  + C    DP +  E     +LF+   ++GWW            +E  EE  G +E+ +E++ + EA   P G GR EP     L+ P RP  SFL F +P+ T+KY I    KW
Sbjct: 1284 ELEKIEEFGGLEDMIASFSLYRGKAKKRDDDDEETQKVVGEFKGTFRIYPLPEAEGVDPDLPET---------------------------------------VFTNLPPNEPIDCVVRVYILSAIDLQPQDPGGLADPYVVVQLGKKKLDNKDQYKPNTLNPIFGKMFELDAVIPVHKDLKITLMDYDLLTRDDMIGETVIDLEQRLLTRYRAKCGIPKTYCDSGPNQWRDHKRPMELLREWCEETEKNFKFYKGTKDGTPDRIVVGYRVYQLDEFGAFRNPNEHLGAKHQRLALHVLNQL-------EFIPEHVETRGLRSPMQPNIEQGKVQLWVDIFPKNEGVLKPSVDITAREPTNYELRVIVWNTSGV-IMDETSITGEQMSDIYVKGWLEGMGDDKEKTDVHYRSLDGDGNFNWRMVFNFLYLPIEKKMVIREKEHFWSLDAKEVRLAPRLNMQIWDNDTFSYDDFLGSCQLDLIKLPKPCQTAKRCGTSRDPGKNGEYV---DLFQQHSIQGWWACY---------QEGIEEPTGKIEMTIEVLNSNEAAVKPAGKGRDEPNQNPHLDEPNRPATSFLWFTSPFKTLKYIIWRNYKW 1829          

Query:  737 SLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELI----IKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKP----KRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKH---AIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMV-KDETISTIFIDLQKIMYTGSKEEE----------GFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVD-VRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLK--TSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRS--------NVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLG 2716
            S K++DFQI V I+E R L GNNI+P+  V    QK+ T+I   TN P YNE FTF+   S  E+ + +    +      +      +++F G    + +  +   + N    F                 +GY+KV   VL  GD+P    K P  +++E++  IE+N L+P+ V+  P       + I+QAED+P M++ +  +IK     I+G  K L D YV+V+F G    T +  ++ +P++ +Q+     FP    R++I + D D V  D+ I T F+ L  I   G +  E           F PT+GP ++N YG+PR F+  +L   D   N+ + EGVAYRGR++I ++T+   +  +  V  +   + V      +RE Y LF   YE T+I +  G    P+ FE+SIG  GN +D+    A+     P     H              Y ++P+ N+KP + + +  ED   R+   N+I +L  +L   +++    +      +   ++   TSI+ ++  I   +  V     ++K    D+  ++++ L+     +   NL  ELK +        N+ + + E N  ++ L D   +PQ  +PD+ ++MI  + R+AY RI A+E++ S+     G +CG    + LK        L     I A +++ LW G
Sbjct:    5 SDKVQDFQIRVKILEGRQLSGNNIHPVVRVAMSNQKRETKIVRSTNKPVYNESFTFNFHTSEAELFDDLFSPAVSAHSYWRWGIRPKKQLFQGLPRPKCAYISSFAFLNVVFLF-----------------QGYLKVTAMVLGPGDEPPIKAKLPPKEEDEDD--IESNCLMPMGVARQP---ALFNLRIFQAEDIPQMDSGMGRSIKKFFKGIFGGAKGLVDPYVKVNFCGKKIETSIKYQDDNPEFKEQVKIPLMFPSMCERIKIQLYDWDRVGNDDCIGTAFLSLSSISGQGDEGNELLVILHPSLLCFPPTFGPCFVNFYGSPREFS--ELPDQDDALNKGIGEGVAYRGRVLIELETTLGSNEIEQEVSQIETEDIVRVQPFLRREKYKLFACFYEATMIKDVDG----PVEFEVSIGNYGNKMDESVAPANTAPSNPLFDGCH--------------YNYLPWGNEKPVVVVESFWEDIAFRLEPLNLISRLCDKLEVNVKRVRSALDAPTPPKEDAFVPMVTSILEVL--ISDCIPHVGVLSKSSKHCSYDILGRKVLPLNHRDHDL---NLTTELKSALDFPGAEINMEQTVGELNGYLQRLRDVAIEPQNCIPDVIVWMISGSERIAYYRIPAQEVLFSTTPDACGKICGKTVELRLKYPGKKGQDLKDHPEIPALVRVELWFG 650          

Query: 2828 FQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVK---GL----------------PTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLD-LRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDS 4033
            FQ+  Y++ AR+++  D+SG++DP+ R+  +     + +  +T  P WD+TLI    +F+   ++ + +PP VV+E+FD D    ++FLGR   +P   I G++    KL W+ I  G    GEILAA +L  +     + T K   GL                PT +D +           GE+    L + + IRP L     E+L WGVR +++ ++  +K                 P +  +I G  I+SD +TD    PNF   ++    + LP    + PP+ I   ++  FG                             K T+   S+KSL  F     T      G    +G A                    PG  +  + V+P+ E     DWW++YYA++    DS
Sbjct:  932 FQMWAYVYQARDLLAKDESGMNDPYVRVAFANQSQMTEVKQKTLCPTWDQTLIFHVDLFDSLENI-QRNPPTVVMELFDKDQVGKDDFLGRTEFKPYPRIHGNEGPACKLLWYPISHGDEDGGEILAACELFLVSFIFFQCTTKLETGLLNFHLQDDGVVNIPHPPTPRDAE-----------GEI----LPVRDRIRPVLQKTVVEVLCWGVRNMKKYQLASIK----------------SPSVQFEIGGEIIQSDILTDAKKFPNFGRPILPRKIINLPVEEMYTPPMNIRIHDNRTFG----------------------------RKPTVAVHSIKSLTRFRCAAPTPA----GQIQVEGPA-------------------APG--QPAEGVVPEAES-HKFDWWSKYYASLNQTEDS 1267          

Query:  737 SLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDK-PKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHA--IYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDND-MVKDETISTIFIDLQKIMYTGSKEEE------GFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDNKYFH-IPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARR---YLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGL 2719
            S K +DFQ+ V I+E R L G NI+P+  V    Q + T++K+ TN PFY+E F F+  MS +E+ + II     +      ++++    ++G F  D    Y   GH+  RKW  L DP    +G KGY+KV + VL  GD+ P +   DDN+   +IE NLL P  V   P      ++ +Y+AED+P M++  I  IK    +  E K L D Y+  SFAG   RT++   +  P++NQ++    +FP    RL++ + D D +  D+ I T  + +  I   G   E        FLP +GP +IN+YG+ R   Y+ L       N    EGVAYRGR+++ ++T           D++    +S     +R  Y LF    E ++++   G    P+ FE+SIG  GN LD    V      TP    V           YD  Y++ +P+ + KPC+ + +  ED   R+   NI+ ++   L   + + +  +SLE N Q       L + +  LI  + K +  + +   T     LD+K Q  +RL +EK+ +  + + L    ++V E + E    ++ L D   +PQ  +PD+ I+M+    R+AY RI A ++++   +   G  CG +  +++K        +     + A +++ +WLGL
Sbjct:   11 SNKPQDFQVRVRIIEGRQLSGQNISPVARVTVANQTRQTKVKISTNKPFYDETFFFNFNMSPMELFDEIISFEVFN------SRKLRANAMIGYFKCDIGFFYEEPGHAAIRKWVLLTDPDDKMAGVKGYLKVTVMVLGPGDEAPVKSAQDDND---DIETNLLQPSGVMLRP---ATFSLKVYRAEDIPQMDSGFIEGIKRVLRVGEEQKELVDPYLLFSFAGMKARTRIHYNSDHPEFNQELNVQFKFPSMCERLKLQMFDWDRLTADDCIGTAHLPMSAISGQGEDGESWVERNISFLPMFGPCFINVYGSTR--EYSDLPDEYDDLNLGNGEGVAYRGRVLVELETKLGVTPQSPTDDLQSHEIISVQPYLRRRKYKLFACFLEASMVSCSDG----PVEFEVSIGNYGNKLD--LSVPPSSSTTPPTNAV-----------YDGCYYYFLPWGDTKPCVCVESHWEDIGFRLGTKNILTRMCERLEVNMDKVN--LSLEANAQPAETATLLISLLDQLINDVRKPLPKIDN--NTPGVNDLDLKLQE-VRL-MEKLSISEEAIKLRESATDVREALGEIEGFLQRLRDLTVEPQNSMPDVIIWMLSGTKRIAYYRIPAFDVLYEPYSEACGENCGQVQNIFMKYPGKKQQNIEDYPEVPAHVRMMIWLGL 648          

Query: 2792 PPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDM-KTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCD 3730
            P  +I Y     +QLR YLF AR+++ SD  G+SDP+AR++     + +    +T  P WD+TLI D +    + + +  +PP V++E++D D    +EF+GR   +P V + G      +L W+ + RG    GEILAAF+L  + + K +  + +G     D+              M  N   +P  IRP +     E+L WGVR +                K+F +  V+ P I  +  G+ + S  I +    PNF+  L F D+ LP    + PP+ I   ++  FG K +VG  A+ +L   ++CD
Sbjct:  901 PRMFITYEKPHRYQLRAYLFQARDLLASDPDGVSDPYARVVFGTRSSVTETLARTLCPTWDQTLIFDEVNIYGSIEQVAENPPAVIIELYDKDPVGKDEFMGRCVVKPLVKLNGQGPPAPRLLWYDVERGDEYGGEILAAFELFLVSITKVQNASKRGNDEGTDLPFAPP---------MKGNLFLVPNGIRPVMQRTAIEVLCWGVRNM----------------KKFQLASVSSPSIEFECGGHVVNSTIIKNTQKNPNFDQPLFFFDVYLPKEELYTPPMNIKVRDNRSFGRKPMVGLHALKSL-QRFRCD 1188          

Query: 4688 PVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDR---VDIDDRSFFAETMIEDDDGSQIKSLEPLALE---VLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAG-TAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC----DPFQLSEACAKF-NLF--RNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEP 6022
            P+  +VRVYII  ++L   D +G  DPY++V +G KE   R++Y  KTLNPVFG+  E   + P    L + + D+DRL++DDLIGETTIDLE R LS +  +CG+  +Y   G   W+D + P  IL+ +C +  +  P +    D+   V + +  F     IED D  Q++S E  + E    LH  H +     +VPE++ETRPLY P +P I+QG L++WVD++P    +I  PI+I PRK   + LR  +  T  V L   +  T EK  DI++K W++  D  L KTDVHY+SLSG G FNWR  + F +L  E  +  ++K ++   E E K    L +Q+ ++     D  +G     L + P+P    R C    DP         F +LF      +RGWW    +       +         V++ +E++TAEEA++ PVGLGR+EP
Sbjct:  483 PLKCIVRVYIICGMDLQSQDTDGFGDPYLVVSIGKKEFSTRKDYKKKTLNPVFGEMFEFHASIPSSKDLKITVMDYDRLSRDDLIGETTIDLEQRLLSGYHATCGLPKTYFKSGPYAWRDSKTPKEILREVCLDRGLNRPDFYHKGDQAVTVVVGEDQF----NIEDLDDYQLESNELGSSEQRLSLHALHAM----GMVPEHVETRPLYSPLQPRIEQGKLQLWVDIFPCTEGSIKPPIEIEPRKPKDFVLRVIIWDTTDVELQETS-ITGEKMSDIYLKGWLEEIDEKL-KTDVHYRSLSGDGNFNWRMEFPFSFLTIEKKLHLSKKKLWGKCE-EVKVDAKLKIQIWENDKFSPDDFLGTRSLPLHRLPKPCSNSRWCGTKYDPGVRQNPDDDFVDLFTLHTHSIRGWWACWQHDSPSGKPKGK-------VDMSLEILTAEEAKARPVGLGRSEP 923          

Query:  737 SLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIF-TGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPN-IEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDND-MVKDETISTIFIDLQKIMYTGSKEEEGF 1606
            S K + +Q+ V I E R + G NI+P+  V  G +KQ+T +K  TNSP YN+   F+   S  E+ + ++ +        V   R F +  +LG F  D  ++Y    H+F RKW  L       S ++GY+KV   VL  GD+P          N N   +NLL+P  V    R+     + +Y AEDLP   + I+  +K A   E K   D Y+  SF G   +TK  +   +P +NQ +      P     +++ + D D   K + I+T ++ L +I  +G    EG+
Sbjct:   15 SSKPQHYQVRVKIHEGRQIPGTNIHPLVRVSVGNKKQSTSVKRSTNSPTYNQTLFFNFHASEAELFDELMTL-------EVFNSRTFLSDSLLGFFESDIGTLYELPDHAFLRKWVLLTGAGVQESEDEGYLKVTAMVLGPGDEPPLSVFVAIVNNYNFFGSNLLLPAGVR---RQQAVFQLRVYFAEDLP-QKSAILFFLKSA--EERKKSVDPYLTFSFCGKQIQTKTQHHENNPVFNQMLQLPVMLPSMCENIKLQLWDWDSFSKHDCIATAYLPLSEI--SGKSYGEGY 292          

Query:  758 QISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEG-KALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDND-MVKDETISTIFIDLQKIMYTGSKEEE---------GFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDNK-YFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSII-NLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGY 2740
            Q+ V +++ R + G NI+P+ +V  G Q + T++K  TN P+++E F F+         + +I     +      +Q++    ++G F  D    +  + H   RKW  L DP+    G KGY+KV + VL  GD+   P   D+E++  +E NLL P  V     +    A+ +Y+AED+P M+++   ++K    GE  K L D YV VSFAG   RT+   ++  P++ +++  + R P    RL+I + D D    D+ I T ++ L  I  +G  EEE         GFLPT+GP ++N YG+ R   Y+ L       N  + EGVAYRGRL++ ++T+   ++     D+   + +      +R  + LF    E T++          + FE+SIG  GN LD      +  EP+       S + +     +D   Y+ +P+ + KPC  + +  ED   R+   N++ +    L + + +    +  +        L  +++ +LI    + +  V S    A     D+ +++  + + EK+ +  +   L    +++ E M E     K LE    +PQ  +PD+ I+M+  N RVAY RI A E++ S     +G  CG + +V+LK        +     +  ++ + LWLGL +D   +
Sbjct:    1 QVRVRVIQGRQIAGANISPVVKVTVGNQARQTKVKKSTNRPYFDEMFFFNYQEIASTFFDNLISFEVFN------SQKLRANALIGSFESDVGFFFDQQDHMVNRKWVLLTDPEDKMEGAKGYLKVTVIVLGPGDEA--PINHDDEDD--LENNLLQPAGVI---MRTSIFALKVYRAEDIPQMDSSFADSVKKVFMGEANKELVDPYVLVSFAGKQSRTRCHEKSDHPEFKEELFVSFRLPSMCERLKIQMYDWDRFTADDCIGTAYLPLSAI--SGQTEEEVISSLCNCSGFLPTFGPCYVNFYGSTRE--YSDLPDEFDDLNLGIGEGVAYRGRLLVELETTLGENAMSPSEDLDDEDIIRIQPFLRRRKFKLFACFLEATMV----ACPDSSVQFEVSIGNYGNRLD------TSVEPS-------SSSTAACNPVFDGSFYYFLPWSDSKPCCSVESHWEDIAFRLEAFNMLTRTLERLQKNMDKVELALDAKMPAPELAALVIALLGDLIQDCRRPLPEVSSKTAGAN----DLDFKKYAQREKEKLAIAEEARKLRDNATDIEEAMNEIEGYQKRLELVAVEPQNCMPDVVIWMLNGNKRVAYHRIPAYEVLFSHSEQARGKHCGKVLSVFLKYPGKKQFDIEDHPEVPCKIDVALWLGLEKDQDAW 636          

Query: 2753 PEGYNRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            P  +  E  +   P  +I +     FQLRVYLF A +++ +D  GL+DP+AR++  +    +     T  P+WD+TLI ++++     +++  SPP +V+E+FD D    +E++GR    P+V + G      +L W+ + +G +  GEILAAF+L         +++ G+       +     +   Y  M+++   +P  IRP +     E+L WGVR +                K+F +  V+ P I  +  G+ + S  I +    PNF+  L F D+ LP    + PP+ I   ++  FG + IVG   I +L
Sbjct:  870 PAVFQMEGGNTSTPRMFIKFEKYQKFQLRVYLFQASDLLAADSDGLADPYARVVFQKQSQTTCTKYHTLCPMWDQTLIFEDVMIYRTQELVVESPPKIVIELFDKDQVGKDEYMGRCVATPEVKLHGQGPPAPRLLWYPVTKGDMEGGEILAAFELF--------LSIWGMRPCTKFLRGDEGADLPYYPPMNKDLYMVPSGIRPVVQRTAIEVLCWGVRNM----------------KKFQLASVSSPSIEFECGGHVVNSTIIKNTQKNPNFDQPLFFFDVYLPKEELYTPPMNIKVRDNRSFGRRPIVGVHCINSL 1164          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIK-----TSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKV----------------------ASEKEPTPENQYVH-SMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNR-ECFSG-----KMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P S +  D+QIS+T+VEAR L G N++P+  V  G  K+ T +K  TN P+YNE+F FD  +    + + IIK+  +   N      + +G ++G F +D  +VY    H F+ KWA L DP   T+G KGYVK DI+V+  GD  K P   +  +  +IE NLL+P  +    R+     V IY+AE LP MNT I++N+K A  GE + L D YV+V FAG  G+T V   +Y P WN+QI+FTE FPP   R+++ +RD+D V D  I T FIDL+KI   G K   GFLPT GP+W+N+YG+ R +T   L+   Q  N+ + EGV++R RL++++      T+     S   V V   + +S +  GK E + LFG   E T+++  +G   KP+TFE++IG  GN +D  +K                       +SE E   E   V  S T        D  YFH+PY  KKPC+++ +  +D R R++  NI++K+  +L E +     +I  EK    RR L+  +  L     + V+        A +T LD +  +    +L+ M  + + L  ++K++ V ++++   + ++ L     +PQ+ +PD+FI+M+  N R+AYARI +++I++S++  E G  CG +   +LK L          + +QA+L++YLWLG+ R  + +  GLP G+   +   G      +PP  + Y  + +FQLR +++ AR++  +D SGLSDPFAR+  S H   + + ++T  P WD+ L+ D++        L+  PP +VVEI+D D+    EF+GR F +P + +  + Y   +    L+++ IYRG   AGE+LAAF+L+++    K      LP ++          D+  G +    L +P  IRP LS +R E+L WG+R L+RI +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG  A+++L
Sbjct:  246 MEPGSGRPVDYQISITVVEARQLIGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVPPDVLFDKIIKLSVIHSKN-----LLRSGTLVGTFKMDVGTVYFQPEHQFYHKWAILSDPDDITAGCKGYVKCDIAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGIP-AERQWARFYVKIYRAEGLPKMNTTIMANVKKAFIGENRDLVDPYVQVQFAGQKGKTSVQKSSYEPIWNEQIVFTELFPPLCKRIKVQIRDSDKVNDVAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRQYT---LMDEHQDLNEGIGEGVSFRARLLVSVAVEILDTTSPEIISSSDVQVEGVSNISESATGKMEEFFLFGSFLEATMVDRKIGD--KPITFEITIGNYGNQIDGVSKSPAAKKKKKDGENEEDENELILNSSEDEAEEEGDLVSVSTTPLMKPVITDRNYFHLPYFEKKPCVYIKSWWQDQRRRLYNSNIMDKIADKLEEGLNDVQEIIKTEKAFPERR-LRGVLEELSVGCSRFVALANKDVNLAGRTKLDRERLKSCMRELDSMGQQAKQLRTQVKKNTVKDRLKLAQSFLQRLRFLADEPQHSIPDVFIWMMSNNKRIAYARIPSKDILYSTVEEETGKDCGKVKAAFLK-LPGKKSFGPAGWTVQAKLELYLWLGVNRQRKDFLSGLPNGFEEVKAVEGGPGFLSLPPLSLVYSMKQVFQLRAHMYQARSLFAADSSGLSDPFARVFFSTHSQVTEVLSETLCPTWDQLLVFDDVELFGEASELREDPPIIVVEIYDQDTVGKAEFIGRTFAKPTIKMCDEHYGPPRFPPQLEYFQIYRGNCTAGELLAAFELLQIGQGGK----ADLPPIEG-------STDSERGPI----LPVPLGIRPVLSRYRIEVLFWGLRDLKRINLAQ----------------VDRPRVDIECAGRGVQSALIQNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYILVGTHAVSSL 1231          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAP-IDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSC--DPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            ++ ++++  ELE+  +FG F D   +F+LYRGK  +DD++  + DR  G FKG++C+Y +   +    +   +                                     + +++++   +P++ +VR+Y+++A +LHP+D+NGK+DPYI+++LG  EV+D+ENYI K LNPVFGK  ++E TFP ES L V +YDWD +  DDLIGET IDLENR+ S  + +CGI  SY  HGY  W+D   PT IL  LC+E  +  P Y     +V + +R F   T IED++G + ++ E LAL VL+HW EI   G KLVPE++ETRPL  P+KPGI+QG +EMWVDM+P+    P P +DI+PRK   YELR  +  T++V L + ++FT EK+ DIFV+ W+K    D Q TDVHY SL+G+G FNWRFV+ F+YL AE+ IV ++K S++  DE EYK P  L +QV D+    +D  +G  +  L++FP+ AK  + C  D  +        ++F+ K+V+GWWP +   ++++ +          VE E+ LVTAEEAE +PVGLGR EP PLE P RPD S + FL P  +I+YFI +  +W+++K   + + LL++ LF+Y+ PG     +V K+ G
Sbjct: 1365 VDELVVFNKELES--EFGNFEDWLHTFNLYRGKAGDDDEHALDDDRIVGRFKGSLCMYKLPLSEEITREAGYDP-----------------------------------NMGMFQSIPHNDPINVLVRIYVVRATDLHPADINGKADPYIVIRLGKTEVKDKENYISKQLNPVFGKSFDIEATFPMESMLTVSVYDWDLVGTDDLIGETKIDLENRFYSKFRATCGISSSYSVHGYNIWRDPMKPTQILTRLCKEGKIDGPHYGP-GGKVKVANRIFTGPTEIEDENGLKKQTEEHLALTVLNHWEEIPRVGCKLVPEHVETRPLLNPDKPGIEQGRIEMWVDMFPSDMPAPGPALDISPRKPKRYELRVIIWNTDEVILEDDDYFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFVFPFEYLVAEEKIVISKKESMFSWDETEYKIPPRLTLQVWDADHFSADDFLGAIELDLNRFPRGAKTAKQCSLDMIRNEHELPTISIFKQKRVKGWWPFVARDENDEMELTGK------VEAELHLVTAEEAEKSPVGLGRNEPDPLEKPNRPDTSLMWFLGPLKSIRYFIWHNYRWLILKALGLILLLLMLGLFLYSIPG----YLVKKLLG 1956          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANI-YFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEY--FSPSTGS 508
            M+L V+LK +      GD+  K+ FR +   S   +   ++ +F + F WPIA ++D+N++L ++ +N ++V  ++L+G   +    +  E  + + + L+DE        V  EI Y     STG+
Sbjct:    1 MALVVHLKKVSHLRGKGDRIAKVSFRGLPLCSRVAENCGDVAHFNETFRWPIASRLDENEMLEIQVFNYSKVFSNRLVGTFCMVLQKVAEEGHLELTDTLIDENNTSIKTSVTIEIRYQAMDGSTGT 127          

Query:  725 IDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIA-----IKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDY----AKVASEKEPTPENQYVHSMTQSRFAYTYD---------------NKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSG-----KMPPKYIDYLD-ESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNI-IFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAK----LQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENK-LRIPEFIRPHLSTFRFE-ILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNL 3709
            ++P S +  D+Q+SVT++EAR L G N++PM  V  G+ K+ T +K  TN P+YNE+F FD  +    M + I+K+  +   N      + +G ++G F +D  ++Y+ + H F+ KWA L DP   T+G KGYVK DI+V+  GD  K P   +  +  +IE+NLL+P  V    R+     + IY+AE LP MNT+I++N+K A  GE K L D YV+V FAG  G+T V    Y P WN+QI FTE FPP   R++I +RD+D V D  I T F+DL+ I   G K    FLPT GP+W+N+YG+ RTF+   L+   Q  N  L EGV++R RL+I+     + TS    S    V V     +S +  GK E + LFG   E T+I+  +G   KP+ FE++I   GN +D       K    K    E + +H+ ++       D               + YFH+PY  +KPC+++ +  +D + R++  NII+ +  +L + +   + +I  EK    RR L+  +  L    + +    K  +  + +T LD +  +L   ++E + ++ + +  ++K+S V +K++     +  L     +PQ+ +PD+FI+MI    R+AYARI +++I++SS+  EKG  CG + T++L R+          + +Q++++IYLWLGL R  + Y  GLP G+     S        PP  + Y+  + +FQLRV+++ AR++  +D +GLSDPFAR+  S     + +  +T  P WD+ L+ +N+ +F  A + L+  PP +V+EI+D D+    +F+GR F +P V +  + Y   +    L+++ IYRG  AAGE+LAAF+L+++    K      LP +            +   +MD    L +P  IRP LS +R E +L WG+R L+R+ +                  V++P++ I+ AG  ++S  I ++   PNF   + + ++ LP +    PP+ I   +   FG   +VG+ A+++L
Sbjct:   47 MEPSSGRPVDYQVSVTVIEARQLVGLNMDPMVCVEIGEDKKYTSMKESTNCPYYNEYFVFDFHVPPDVMFDKILKVSVIHSKN-----LLRSGTLVGTFKLDVGTIYS-QPHQFYHKWALLSDPDDITAGGKGYVKCDIAVVAKGDTIKTPHKANESDEDDIESNLLLPEGVP-AERQWARYYLKIYKAEGLPRMNTSIMANVKKAFIGENKDLVDPYVQVQFAGQKGKTSVQKSCYEPIWNEQIAFTEMFPPLCRRMKIQLRDSDKVNDVAIGTHFLDLRNISNDGDK----FLPTLGPAWVNMYGSTRTFS---LLDEYQELNDGLGEGVSFRARLLISLGVEILDTSSPEISCSTEVQVEGVPNISESATGKVEEFFLFGSFLEATMIDRKIGD--KPINFEVTI-YYGNEIDGALQPKPKGEKGKGDEEETELIHNSSEEEMEDDGDLTSVATTPPMKPVITDNYFHLPYFERKPCIYIKSLWQDQKRRLYNSNIIDNIADKLEDGLNDVNEIIKTEKAYPERR-LRGVLEELSQGCQFLALANKD-QNQSGRTKLDKERLKLCLSEVEAIGLQAKAMRSQVKKSTVRDKLKLSQNFLSKLRFLADEPQHSVPDVFIWMISNGKRIAYARIPSKDILYSSIDEEKGKDCGKVKTIFL-RIPGKKGFGPAGWTVQSKIEIYLWLGLTRQRKDYLNGLPNGFEENKLSKGPGLPSTPPISLTYMSVKQIFQLRVHMYQARSLFAADSTGLSDPFARVFFSTQSQVTEVLAETLCPTWDQLLVFENVELFGEAVE-LRDDPPIIVIEIYDQDTVGKADFMGRTFAKPVVKMADEHYGPPRFPPQLEYYQIYRGNCAAGEMLAAFELLQIGPNGK----ADLPPI------------DGPTDMDRGPILPVPLGIRPVLSKYRIEQVLFWGLRDLKRVNLAQ----------------VDRPRVDIECAGKGVQSALIPNFKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSNAVSSL 1025          

Query: 4340 MYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDN-FENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVP-GKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAP-IDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEAC--AKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAP 6040
            +YP ELE+  +F  F D   +F L+RGK  +DDD    + DR  G FKG++C+Y +  +   D+  +                                       + +++N+ + +PV+ +VR+Y+++A +LHP+D+NGK+DPYI +KLG  E++D+ENYI K LNP+FG   ++E TFP +S L V IYDWD +  DDLIGET IDLENR+ S H+ +CG+     NHGY  W+D   PT IL  LC++  +  P Y     RV +++R F A T IED++  + K+ E LAL VL HW EI   G KLVPE++ETRPL  P+KPGI+QG +E+WVDM+P     P P +DI+PRK   +ELR  +  T++V L + + FT EK+ DIFV+ W+K    D Q TDVHY S++G+G FNWRFVY FDYL AE+ IV ++K S++  DE EYK P  LN+QV D+    +D  +   +  L++FP+ AK  + C    ++        ++F+ K+++GWWP +   ++++ +          VE E+ L+T EEAE +P G GR EP PLE P
Sbjct: 1112 VYPKELES--EFDNFEDWLHTFYLFRGKAGDDDDQTVADEDRIVGKFKGSMCMYKVSDDAPRDMSFDS-------------------------------------NMGMFQNIPNNDPVNVLVRIYVVRATDLHPADINGKADPYIAIKLGKTEIKDKENYISKQLNPLFG-SFDVEATFPMDSTLTVSIYDWDLVGTDDLIGETKIDLENRFYSKHRATCGVA----NHGYNVWRDPMKPTHILAKLCKDGKLDGPHYGP-GGRVKVENRVFMAPTEIEDENLKK-KTDEHLALCVLTHWEEIPRVGCKLVPEHVETRPLLHPDKPGIEQGRIELWVDMFPKEMTAPGPALDISPRKP-KFELRVIIWNTDEVVLEDDDIFTGEKSSDIFVR-WLKGQQEDKQDTDVHYHSITGEGNFNWRFVYPFDYLMAEEKIVISKKESMFAWDETEYKIPPRLNLQVWDADHFSADDFLA-IELDLNRFPRGAKTAKQCTIEMVTNEAEMPMVSIFKQKRIKGWWPFVARNEEDEFELTGK------VEAELHLLTGEEAEKSPAGEGRNEPEPLEKP 1629          

Query: 4340 MYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEI-VPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVT 6217
            +Y  ELE   DFG F D   ++ L+RGK  E++ + +  +RF G FK   C+Y +  E+  +  D                                         R+ + +   +PV  ++RVY++ A NLHP+D +GK+DPYI+++LG  E++DR+NYIPK LNPVFG   E++ TFPQES L V IYD+D +  DDLIGET IDLENR+ S H+ +CG +P+ ++ GY  W+D   P+ +L  +C E+ +  P +     ++ + D+ F  +T+   +    ++S E L+L++LH W EI   G KLVPE+IETR LY   +PG+ QG ++MWVDM+P     P  P+DI+PRK   YELR  +  TE V L + NF T +++ DI+VK                                          +V  + +++ +D+ E K P  L +QV D   + SD  +G  +  L  FP  AK  ++C    L+    + ++F+ K+ RGWWP   + +               VE E  LVTAEEAE NPVG  R EP PL  P RPD SF  F+NP+    + +    K  +I   ++F+  L +AL  Y  PG+IS  ++ 
Sbjct:    1 LYNRELE--ADFGQFDDWVNTYELFRGKANEEEGSSD--ERFVGKFKARFCLYKLAEEEWGEGSDPGF-------------------------------------FRVSRGIPANSPVQVLIRVYVVSASNLHPADPDGKADPYIVLRLGKNEIKDRDNYIPKQLNPVFG-SFEMQATFPQESLLSVVIYDFDLVGGDDLIGETRIDLENRFYSRHRATCG-LPTEYSEGYNAWRDSLKPSELLSKMCRENGLDAPRFS--PGKISVADKVFHGKTLYMHE--QPVESYEHLSLKILHRWSEIPAVGCKLVPEHIETRVLYNKARPGMDQGQVQMWVDMFPMDLPHPGPPVDISPRKP-KYELRIIIWNTEDVILDDSNFLTGQQSSDIYVKV----------------------------------------VVVRKRDNIFSLDKTEQKLPAILILQVWDFETLSSDDFLGTLELDLHGFPPGAKTAKACKAEMLTGRTERISIFQQKRARGWWPFSKSGELTGK-----------VEAEFHLVTAEEAEKNPVGRARKEPEPLPKP-RPDTSFSWFMNPFKCFFHLVWRNYKKYIITALILFILALFLALLFYTLPGAISQKMIN 528          

Query:  737 SLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGE--GKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDND-MVKDETISTIFIDLQKIMYTGS-------KEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIR--QTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEK-GIMCGMMNTVYLKR-LDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGY 2740
            + K +DFQI V +VEAR L GNNI P+ +V+   Q   T IK   N+PF++E F +++ M   ++ E  I  R +  S ++ A  +     +GEF +D   VY    H   RKW  L DP   +SG KGY+KV + V+  GD+P     D +++  +IE+NLL+P  ++    +   +++ +++AED+P M+   + +IK     E   K L D ++E  FAG    T+++ +N +P+WNQ +    +FP    R+++ V D D +  ++ + T ++DL KI  +G        + E GFLP +GP +INLYG+PR F  T L       N    EGVAYRGR+++ + T     + K   ++      ++ ++  R  Y L    +  ++I E     G+P+ FE+SIG  GN LD   K  +            S TQ   A    N+Y+++P+ N KP + + +  ED   R+   NII  +   L   +   + + L  +  N  A  +L+  +  LI  +E+  +      G +  T LD++ ++  R D+    +K   L +  + S + + + +  T V  L+    +PQ  +PD+ I+M++   RVAY+RI A EI+ S+ + +  G  CG   TV+LK  +D +         +  Q+++ +WLGL  D + +
Sbjct:  170 ATKPQDFQIRVRVVEARQLPGNNIKPVVKVHVCGQTHRTRIK-SGNNPFFDEMFFYNVHMLPSDLFEQSISFR-VYNSYSLRADSL-----MGEFKLDVGYVYDEPAHCVMRKWLLLNDPDDSSSGAKGYLKVSLFVIGTGDEPLVEKRDCDDDQDDIESNLLLPAGMT---LRWATLSLKVFRAEDIPQMDDAFVQSIKEIFGAEENKKNLVDPFLEARFAGKKLCTQIIEKNANPEWNQVLHLQVKFPSMCERVKLTVFDWDRLTGNDAVGTTYLDLAKIASSGGEIEGNPVESEVGFLPVFGPCYINLYGSPREF--TGLPDPYDDLNFGKGEGVAYRGRILVELSTKLDEKAEKTIDNIHIKR--TSIISILRRKYCLCAVFHSASMIQEP----GEPIQFEVSIGNYGNKLDTTCKPLA------------STTQYSCAVFDGNQYYYLPWANTKPVVVLTSFWEDISHRLNAVNIILCITHRLQSNLEAFKVAILAKVPDNKLAEVWLQL-LDQLIEDLERFPT--PELEGCSNLTSLDIQLKK--RRDITLNSIKEAVLRMRQEASEIRDTLSDIETWVDKLKQLAEEPQNSMPDVVIWMLRGEKRVAYSRIPAHEILFSTYSEQACGKNCGKTQTVFLKYPMDKA-----KGLKVPVQIRVSMWLGLSADEKKF 811          

Query: 2777 FSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKST-IFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGD 4021
            F    P     +    M+ LRVY++ ARN++  D    SDP+A +    H++K+T     T +P WD+TLI +++     P  +   PP+VV+E +D D    +E LGR  C P V +  +   + +L W  I +    AGE+L A +L+  D K+    +  LP ++                  EN   +P+ IRP +     EIL WG+R +                K + +  V+ P + ++  G R+E+  I +    PNF  N++F+ + LP    + PPI +   +   FG K +VG C I +L D ++CD                                I++EG       A +    +    P+ DV      T+E+  P+L + +E E+ DWW+++YA+ G+
Sbjct: 1071 FGANTPTVSCTFDRSYMYHLRVYVYQARNLMSMDKDSFSDPYAHVSFL-HVSKTTEKLKATLNPTWDQTLIFNSVEIYGDPQKIAHRPPDVVLEFYDEDQVGKDEMLGRSICTPLVKLSPEMDQSPRLFWHPIIQKGQRAGEVLVAAELILKD-KSGDSDLPLLPPMR-----------------AENLYMVPQGIRPVVQLTAVEILAWGLRNM----------------KPYQLASVSSPSLVVECGGQRVETAIIKNMKKSPNFPGNILFIKVLLPKDEMYTPPIVLKVIDHRPFGRKPVVGQCTIASLED-FRCDPY-----------------------------VIVSEG-------ARSSKMALMMASPHKDVAI----TMEESSPLL-EAQEKETVDWWSKFYASTGE 1409          

Query:  719 KHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEG--KALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKM-------ADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEK-GIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGL 2719
            K   P + + +DFQI V ++E R L G +I P+  V    +   T ++   N+PF++E F +++ MS  ++                                       ++ H+  RKW  L DP   T G +GY+KV I ++  GD+    +     E  ++E+NLL+P  VS    +   +++ +Y+AED+P  +   +  +K  + GEG  K L D Y+EVSFAG    TK++ +N +P+WNQ I                      VKD+ I T F++L +I ++G   E GFLP +GP ++NLYG+PR   Y  L    +  N    EGVAYRGR+++ + T       K  VD  P + V      +R  Y L    +   ++ E     G P+ FE+++G  GN LD   K             + S T + FA  +DN Y+++P+ + KP + + +  ED   R+   NI+     +L   +      IS ++       +   +++ I  IE++V  + +       T+LD++ + L     E     +  +A  +K     E+ R+  + V  +ED +        +PQ  +PD+ I+M +   RVAYAR+ A +I++SS + +  G  CG + T++++      +  N    I A+L+  +WLGL
Sbjct:  139 KRNKPLASEAQDFQIRVRVIEGRHLPGIDIKPVVRVLFDGKTHRTNVR-GGNNPFFDEMFFYNVNMSLSDL---------------------------------------SDEHAIMRKWLLLKDPDDSTMGARGYLKVSIIIMGTGDEAPIENRLFRAEQDDLESNLLVPAGVS---MRTATLSLKVYRAEDMP-QDDATVQTLKQFLGGEGDKKNLVDPYLEVSFAGKKVCTKIIQKNANPEWNQLISLN-------------------VKDDVIGTTFLNLSQISHSGGNVEVGFLPAFGPCFVNLYGSPR--EYGDLPDRFEELNFGNGEGVAYRGRVLVELSTHLDKKVEK-NVDDIPRDDVLVAQFQRRRRYSLCSVFHSACMLQEP----GGPIRFEVTLGNYGNKLDSTCKP------------LVSTTPNCFA-VFDNHYYYLPWADTKPVVILTSYWEDISHRLDAINILLFTADQLESNLNLLKTAISAKEPESRLTEIWLKLLDHI--IEELV--LPALEDRLNVTVLDLQKKNL----REAAVYNIMQMACCMK-----EEARDIGSTVADIEDWLDRIKQLAEEPQNSMPDVIIWMFRGEKRVAYARVPANQILYSSFSKQACGKHCGKIQTIFMQY----PMDKNKGVKIPAELRFNMWLGL 715          

Query: 4664 YKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSF----FAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPA-PIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCD----PFQLSEACAKF---NLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEP--MPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILI 6130
            +K L +  P + +VR+Y+++ I +   D NGK DPYI + LG K + DR+NY P TL+P FG   EL  T PQ+  L + +YD+D+ ++D+ +GET IDLE+R LS  +  CG +P  +  G  +W+D   P+ IL+++ +   VP P  ++    +    + +    FA  +I    G +    E L+L VL +         LVPE++ETR L    K  + QG ++MWVD++P    +P  P +I+PRKA  Y LR  +  T  V L + +  T EKT DI+VK                      +  +NW                         D+ EY+ P  L +Q+ D+  I  D  +   +  L +   PAK    C     P       +K    +LF  K VRGWWP        ++         G VE+ +E+V  +EAE  P G GR EP   P   P RP  SF  F N  + +K+  + + +WI +
Sbjct: 1375 FKELPESGPQECLVRIYVVRCIEVQSKDSNGKCDPYIKITLGKKTLDDRDNYKPNTLSPEFGM-FELSCTLPQDKDLKIAVYDFDKWSRDEEVGETVIDLEDRLLSYFRPCCG-LPQTYCSGVNQWRDQLKPSQILQNVAKMRGVPPPSIEEDGRSLLFSGKRYHLQDFANILIHSHLGPE---KERLSLHVLRNL-------GLVPEHVETRTLSSSYKSNLSQGRIQMWVDIFPKRLGLPGPPCEISPRKA-KYFLRVIIWNTSDVILDDAS-ITAEKTSDIYVKQ---------------------EQFWNW-------------------------DKTEYRNPPKLIVQIWDNDRISLDDYLS-VELDLLRLVPPAKTPEKCTLKMLPGMKGTVASKAKPTSLFSRKSVRGWWPC------ANAQNGSCVLTQGKVEMTLEIVDEKEAEERPAGRGRNEPNMNPKLDPPRPATSFAWFTNVSSILKFMTRIKFRWIFV 1810          

Query: 2783 GKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKST-IFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFE-ILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGD 4021
            G   P    +    ++ LRVY++  RN+   D +  S P+A +    H++K+T +   T +PIWD+TLI ++I  +  P  + S PP VV+E++D D    +E +G     P + ++ +     KLQW  I +    AGE+L A           K+    LP V   +               E    +P+ I+P +     E +L WG+R ++                 F + PV+ P + ++  G  +++  I ++   PNF  + V L   LP    + PPI +   +   FG K +VG C I +L ++    + D +R      +  R++ +    N   D E             AI+E  D                               E+ DWW+++Y+++G+
Sbjct:  965 GAKTPTVSCHFSSYIYHLRVYIYQGRNLCPMDHNSFS-PYAHVSFL-HMSKTTHVIQNTLNPIWDQTLIFEDIEIHGDPQTVASCPPEVVLELYDSDQVGKDEPMGHCKYPPLINLQPNIGCRPKLQWLPITKKGHNAGELLLA------AELLLKLDDDDLPIVPPRR--------------SEKLYMVPQGIKPVVQLTAIEQVLTWGLRNME----------------AFQLSPVSSPSLIVECGGETVKTAIIKNFKKNPNFPGS-VLLLKLLPKEEMYAPPIVLKVIDHKPFGWKPVVGQCTIRSLGEF----RCDPYRTNSDICMSSRAMMADAQENVVIDVE-----------SRAISETRD-------------------------------EAVDWWSKFYSSLGE 1294          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEYFSPSTGSDNFGSDAFNFPVYNLKTLKRTSKKVTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFKLPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKEVIEKLSESESDEEVTGFVLXXXXXXXXXXXXXXXXXXXXXXXPXXXXXXXXXXXXXXXXXXNPFQPSTKELFLKEEPDNLRMESEYVTDNSWIERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEYFSPSTGSDNFGSDAFNFPVYNLKTLKRTSKKVTLPSENSSDEDEEYYDSDDGDGRDNNIRDDISDISLLPDRDFKLPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAK      PTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHL  LEKN+QARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIII EH+AKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNR+GEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPI+INCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKEVIEKLSESESDEEVTGFVLNDIEINVNSDEDEEDVVDIPDDEPKKKKKKKKKRKKKKRKFKNPFQPSTKELFLKEEPDNLRMESEYVTDNSWIERI MYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIDPEDAEDIDDEEEEDDFNDEDDEEEREEKERRREERELEKQEREDEKKKTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPT+ILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKDEDSDEEDGEEIGGCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKIFVIFMALLIIALFIYNFPGSISNAIVTKMFG
Sbjct:    1 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEYFSPSTGSDNFGSDAFNFPVYNLKTLKRTSKKVTLPSENSSDEDEEYYDSDDGDGRDNNIRDDISDISLLPDRDFKLPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAK------PTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHL-RLEKNIQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIIGEHVAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRFGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPISINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKEVIEKLSESESDEEVTGFVLNDIEINVNSDEDEEDVVDIPDDEPKKKKKKKKKRKKKKRKFKNPFQPSTKELFLKEEPDNLRMESEYVTDNSWIERITMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIDPEDAEDIDDEEEEDDFNDEDDEEEREEKERRREERELEKQEREDEKKKTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTVILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKDEDSDEEDGEEIGGCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKIFVIFMALLIIALFIYNFPGSISNAIVTKMFG 2024          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEYFSPSTGSDNFGSDAFNFPVYNLKTLKRTSKKVTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXFKLPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQYVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKEVIEKLSESESDEEVTGFVLXXXXXXXXXXXXXXXXXXXXXXXPXXXXXXXXXXXXXXXXXXNPFQ-PSTKELFLKEEPDNLRMESEYVTDNSWIERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            MSL V L+ L G  QG + +IK++FRD + ++   KT  +   G RF WPIARK+DK D L++K    NR G DKL GV+ I    L+ +  +N+ E  VDE+M+ITDI + FEIEY SP +G++N G   FN P YNL  L+R    + LPS+ SS E +     ++     +    D      L  +RDFKLPKHIDP SLKI+DFQISVTI EARGL G NINP+FEVYCGKQKQ TE+KMQTN+PFYNE+F+FD  +SRLE+ME II+I+ LSK +++V + IF GKV+GEFSIDAK+VY+NE HSFF KWA LIDPK+PTSGEKG+VKVD+SVLCAGDKPKRP+  D EE+PNIEAN+LIP  +  T R +CEM+V +YQAEDLPCMNT I+SNIK AI G+GKAL D YVEVSFAGYTG TKV++R+YSPDWNQQIIFTERFPP+V+RLRIAVRD+DM+KDETIST+FIDL KIM + +KEEEGFLPTYGPSWINLYGTPRT++Y ++IKGDQGQNQNLAEGVA+RGRL+IAIKT+ QPDS KIGVDVR CNPVSN VAGKRE+YLLF  I+E TLI +++GK  KPLTFE+SIG TG   D+Y+ +  +KE   E+QYVHS+T+ ++AYT+DN+YFHIPY++KKPCL+MI  SEDHRPR+FIPNI++KLK+EL E +RQ ++L S  K VQA RY+K S+     SI+KV+S +KSCRGTAKKT+LDVKYQ+LIR+ LEKMK+        L    +   +++ N+ VK L+DKM DPQ+GLPD+F+YMIQ+NIRVAY RI AR++IHS++ PEKG MCGM+NTVYLK+++ S+L   T+YNIQAQLQIYLWLGLL+DMR YKMGLPEG++++CF+ KMPPK IDY++ES FQLRVYL+M RN+IGSDDSGLSDPF ++II EHI KST+F +TRSPIWDET+IIDNI+FNY P ++K+ PP+VV+EIFDWDSDTDEEF+GRVFC+P V+I+GD+YT++KLQWW++YRGT+ AG+IL +FDL+E+D  +K+I V G P+++++ +MT+++NDN  GE DE KLRIP  +RP +  FR E+L+WGVRQLQRIE++  K++  +  KR GIFPVNQP+I I+I GYRI+SD I DW   PNF DNL+ + LRLP +++FWPP++INC N T+FGLKQ+VGN  IT+L++YY  D+++   ++D  +   +S+ +   F+   +++G+ N+ F+N+D     +     +    PDVT PVPG  EK+   +P+ EEMESADWWTRYYAT+GDL D  + K   E L ESES++E+   +     +  +S+++E++VV+IP+D PKKKKKKKKK+KKKK+K    FQ  STKELFLKE  ++L +E E ++DNSWIERI +Y CELEN+KD+GGF  PF+SFSLYRGKQEE+DD +E  DRF GVFKGNICIYN+          E+   + +  D++ +  +     E+ E + +E    +K  L+LYK L D + VDF+VRVY++K INLHP+D+NGK+DPYILV++G+KE+RDRENYIPKTLNP+FG+C E+EVTFPQESFLLVQ+YDWDRLTKDDLIGETTIDLENRWLSPH+G+CG+M +Y+NHGY+KWKD +LPT ILKSLCE++N+P P YDK+ D V+I  ++F +++MIEDDDGSQIKSLEPLAL VLH+W +IVP  KLV E+IETRPLY+ EKPGI+QGLLEMWVDM+P+GTAIP PIDI+PRK   YELR  ++QTE VRL + NFFT EK+VDI++K+WMKSTDIDLQKTD H++SLSGQGLFNWRFV+ FDYLKAED IVY  K++YEIDE EYKTPCFLNMQVLDS ++MSDTIIG+ K RLSKFP+PAK+Y+SCDPFQ S+ACAKFNLF+NKKVRGWWPL+YNPKDED +EE+G EIGG VE+EM+LV  EEAESNP GLGR EP+PLE P RPDGSFL+FLNPWNTIKYFIKYRLKWILIKI ++ + +LII LFIYNFPG+ S  IV K+ G
Sbjct:    1 MSLIVTLQSLTGVKQGQEGFIKVIFRDHQFRTPNFKTKPSTNLGSRFVWPIARKLDKVDSLVIKFILLNRFGPDKLTGVINIVLSTLMVQQCINLDETFVDEQMRITDIALNFEIEYNSPVSGNENLGKSDFNVPSYNLTKLERHEGHIRLPSDTSSVESDSDNGDNEPSDDIDVKDGDNYSELSLLPERDFKLPKHIDPLSLKIKDFQISVTIYEARGLSGKNINPLFEVYCGKQKQCTELKMQTNTPFYNEYFSFDFRISRLELMEQIIRIKALSKKSHIVTRHIFPGKVIGEFSIDAKTVYSNESHSFFYKWAVLIDPKAPTSGEKGWVKVDLSVLCAGDKPKRPNKTDKEEDPNIEANILIPQILCQTQRSICEMSVYVYQAEDLPCMNTKIMSNIKQAILGDGKALADPYVEVSFAGYTGSTKVISRSYSPDWNQQIIFTERFPPYVSRLRIAVRDSDMIKDETISTVFIDLHKIMNSANKEEEGFLPTYGPSWINLYGTPRTYSYAEMIKGDQGQNQNLAEGVAFRGRLLIAIKTTSQPDSIKIGVDVRSCNPVSNNVAGKRELYLLFASIFEATLITQEIGKKRKPLTFELSIGTTGICPDEYSHLP-KKEENFESQYVHSLTEPKYAYTFDNQYFHIPYRSKKPCLYMIAPSEDHRPRLFIPNILDKLKQELCEYVRQVNYLASRGKKVQAMRYIKKSMETFFISIDKVLSAIKSCRGTAKKTLLDVKYQKLIRMGLEKMKMSWSVTIECLSVCTIDMAIKDLNSFVKFLDDKMLDPQHGLPDVFLYMIQDNIRVAYTRILARDLIHSAIPPEKGQMCGMVNTVYLKKMNFSILPQKTNYNIQAQLQIYLWLGLLKDMRLYKMGLPEGFHKDCFTSKMPPKIIDYMEESDFQLRVYLYMGRNLIGSDDSGLSDPFVKVIIGEHIRKSTVFHETRSPIWDETIIIDNIVFNYNPKIVKTCPPDVVLEIFDWDSDTDEEFIGRVFCRPSVFIRGDEYTSSKLQWWNVYRGTMPAGDILVSFDLIEIDPFSKRIYVPGFPSLENLMEMTAQVNDNSKGEKDEEKLRIPFDVRPPIGLFRLELLIWGVRQLQRIEIISPKRHAVIPIKRMGIFPVNQPRIIIEIGGYRIKSDIIEDWWTHPNFNDNLISVILRLPVNSKFWPPMSINCINYTMFGLKQVVGNHVITDLIEYYVEDKIN--EDLDHESDHLQSLTA--QFDMKANSDGVSNKAFDNKDEKGPEKTKAGVKSDAKPDVTNPVPGEPEKLIRFVPK-EEMESADWWTRYYATLGDLDDPNLYKPEDEILVESESEDEIRRDIFLGYRVETHSEDEEDEVVEIPEDIPKKKKKKKKKKKKKKKKRL--FQHKSTKELFLKEVQEHLILEDEKLSDNSWIERIKIYSCELENIKDYGGFKQPFRSFSLYRGKQEEEDDGYEIQDRFAGVFKGNICIYNV---------QEDNIHEKDLFDEDHDESKLASFGEQDENKTEEELLNEKSNLKLYKFLSDPHSVDFIVRVYVVKGINLHPADINGKADPYILVRIGNKEIRDRENYIPKTLNPIFGRCFEMEVTFPQESFLLVQVYDWDRLTKDDLIGETTIDLENRWLSPHRGTCGLMSTYNNHGYMKWKDSQLPTAILKSLCEKNNIPPPKYDKMNDTVEIMGKTFNSDSMIEDDDGSQIKSLEPLALVVLHNWEDIVPECKLVKEHIETRPLYLQEKPGIEQGLLEMWVDMFPSGTAIPPPIDISPRKPASYELRIVILQTENVRLTDTNFFTKEKSVDIYLKAWMKSTDIDLQKTDTHFRSLSGQGLFNWRFVFQFDYLKAEDSIVYKNKNIYEIDENEYKTPCFLNMQVLDSDLLMSDTIIGRLKFRLSKFPKPAKYYKSCDPFQHSDACAKFNLFKNKKVRGWWPLVYNPKDEDEEEENGLEIGGTVEMEMDLVLGEEAESNPAGLGREEPLPLEKPNRPDGSFLNFLNPWNTIKYFIKYRLKWILIKILIVLIFVLIIVLFIYNFPGNFSRVIVDKITG 2016          

Query: 2519 MIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRYGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKEVIEKLSESESDEEVTGFVLXXXXXXXXXXXXXXXXXXXXXXXPXXXXXXXXXXXXXXXXXXNPFQPSTKELFLKEEPDNLRMESEYVTDNSWIERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIVTKMFG 6229
            MIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIII EH+AKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNR+GEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPI+INCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKEVIEKLSESESDEEVTGFVLNDIEINVNSDEDEEDVVDIPDDEPKKKKKKKKKRKKKKRKFKNPFQPSTKELFLKEEPDNLRMESEYVTDNSWIERI MYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIDPEDAEDIDDEEEEDDFNDEDDEEEREEKERRREERELEKQEREDEKKKTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPT+ILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKDEDSDEEDGEEIGGCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKIFVIFMALLIIALFIYNFPGSISNAIVTKMFG
Sbjct:    1 MIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIIGEHVAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRFGEMDENKLRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPISINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGNDTEGILNEGFENEDGSAINELTDMKEEKPNPDVTAPVPGTVEKVKPVLPQTEEMESADWWTRYYATIGDLGDSTIVKEVIEKLSESESDEEVTGFVLNDIEINVNSDEDEEDVVDIPDDEPKKKKKKKKKRKKKKRKFKNPFQPSTKELFLKEEPDNLRMESEYVTDNSWIERITMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIDPEDAEDIDDEEEEDDFNDEDDEEEREEKERRREERELEKQEREDEKKKTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTVILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAGTAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQKSVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSEACAKFNLFRNKKVRGWWPLIYNPKDEDSDEEDGEEIGGCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKIFVIFMALLIIALFIYNFPGSISNAIVTKMFG 1237          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEYFSPSTGSDNFGSDAFNFPVYNLKTLKRTSKKVTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFKLPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEK 1984
            MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEYFSPSTGSDNFGSDAFNFPVYNLKTLKRTSKKVTLPSENSSDEDEEYYDSDDGDGRDNNIRDDISDISLLPDRDFKLPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEK
Sbjct:    1 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEYFSPSTGSDNFGSDAFNFPVYNLKTLKRTSKKVTLPSENSSDEDEEYYDSDDGDGRDNNIRDDISDISLLPDRDFKLPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGDKPKRPDADDNEENPNIEANLLIPLCVSNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKIGVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEK 616          

Query:  137 MSLSVNLKYLDGAAQGGDKYIKLMFRDVEKKSNRLKTSANIYFGQRFNWPIARKMDKNDILILKCYNANRVGGDKLLGVLQIATGNLINEPSMNVRENLVDERMKITDIIVAFEIEYFSPSTGSDNFGSDAFNFPVYNLKTLKRTSKKVTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFK--------LPKHIDPQSLKIEDFQISVTIVEARGLCGNNINPMFEVYCGKQKQNTEIKMQTNSPFYNEFFTFDLTMSRLEMMELIIKIRGLSKSNNVVAQRIFTGKVLGEFSIDAKSVYTNEGHSFFRKWAPLIDPKSPTSGEKGYVKVDISVLCAGD----KPK----RPDADDNEENPNIEANLLIPLCV-SNTPRKMCEMAVLIYQAEDLPCMNTNIISNIKHAIYGEGKALTDAYVEVSFAGYTGRTKVVNRNYSPDWNQQIIFTERFPPFVTRLRIAVRDNDMVKDETISTIFIDLQKIMYTGSKEEEGFLPTYGPSWINLYGTPRTFTYTQLIKGDQGQNQNLAEGVAYRGRLMIAIKTSYQPDSSKI--GVDVRPCNPVSNTVAGKREMYLLFGGIYETTLINEDLGKNGKPLTFEMSIGITGNLLDDYAKVASEKEPTPENQ--------YVHSMTQSRFAYTYDNKYFHIPYKNKKPCLFMITQSEDHRPRMFIPNIIEKLKRELSEIIRQTSHLISLEKNVQARRYLKTSIINLIPSIEKVVSGVKSCRGTAKKTMLDVKYQRLIRLDLEKMKVKLQNLALELKRSNVYEKMRECNTLVKLLEDKMADPQYGLPDIFIYMIQENIRVAYARIKAREIIHSSMAPEKGIMCGMMNTVYLKRLDNSLLKLNTSYNIQAQLQIYLWLGLLRDMRGYKMGLPEGYNRECFSGKMPPKYIDYLDESMFQLRVYLFMARNVIGSDDSGLSDPFARIIISEHIAKSTIFTQTRSPIWDETLIIDNIIFNYAPDVLKSSPPNVVVEIFDWDSDTDEEFLGRVFCQPKVYIKGDQYTTAKLQWWSIYRGTLAAGEILAAFDLVEMDMKTKKITVKGLPTVKDIKKMTSEINDNRY-------------------GEMDENK-----------LRIPEFIRPHLSTFRFEILMWGVRQLQRIEVVHLKKNPFVASKRFGIFPVNQPKITIDIAGYRIESDKITDWTIQPNFEDNLVFLDLRLPTSTQFWPPIAINCTNSTVFGLKQIVGNCAITNLVDYYQCDQVDNFREIDKTTIDERSVKSLNLFNAGND-------TEGILNEGFENEDGSAINELTDMKEEKPN 3904
            M+L +NLKY+D      D+ +K+ FRD EK +  ++   +IYFG++F WP+ RK+D  D L L+ Y  ++   +KL+G + I+   L+ +  ++ +ENL+D    I  I V+FE+ Y+SP +   N+  D F  P+ + K        +      S         + +    +    D+ S  S   D  F         +P  + P   K ED+QIS+T++EAR L G NINP+ EV  G++ + TE++M TNSP+YN++  F+  MS+ E+ + +I++R L+  N  ++ R+  G ++GEF +D ++VY    H F  KWA L+DPK   SG KGYVKVD++++  G+    KPK    +P  +D+E+   IEANLL+P  + + T R+M E+ V IY+AEDLP MNT+I++ IK AI G+ K L D +V+VSFAG+TGRTKV    Y+P+WN++I+FTE FP    R+R++V D D V +E I+T +IDL +IM  G   + GFLPT+GPSW+NLYGTPR +TY Q+++  +  N+ L EGVAYRGRL+IAIKT  + +S  +  G  V    P+S+   GK+E +LL G  YE ++I+ ++GK  +P+ FE+S+G TGN LD  A    EKE    NQ        + HS T+     T D +YFH+ +  KKPCL+MI+  EDH+ R FIPNI+EKLK E S  + +  H + + +       +K ++   I +IE  ++ +K  R  + KT+LD +  +L ++ LEKM+VK + +  +  ++N+  +++EC  ++K L + + +PQ GLPDIFI++IQ+  R+A+ARI AREI++S++  EKG+    + TV+L++     +   + + +Q QL++YLWLGLLRDM+ ++ GLP GY+ +CF  + PP  I Y ++S FQLR ++FMARN+IGSD+SGLSD FARI++++H+  + +  +T SP WD+TLIID++IF Y+ D++ S+PP +VVE+FD D     EFLGR FC+P V ++ ++Y + +L WW IYRG + AGE+LAAF+L+++          G+P ++ + + +S I   R                    G++  N+           + +P+ IRP L  +R E L WGVR++QR++++                 V++P+ITI+     + SD I    ++PNF + L ++D+ LP +  +WPP+ I C +   FG   ++GN  I+N+  Y    ++       K   +  S    N      D        EG+ N  + +++ +A   L+  ++   N
Sbjct:    1 MALVLNLKYVDNLDNRCDRIVKINFRDFEKTTKVVRGKDSIYFGEQFQWPMGRKLDPIDTLELRLYQYSKYLNNKLIGSMTISLQKLLEDYKISYKENLIDSNHSIIRITVSFELTYYSPDSQIANWRQDEFENPITDRKLSDADDISIDSHGMGSDKRTLIDPQTGEIGEFNYGQTDNESVESGEDDESFAATNARTLGVPLALHPTLHKTEDWQISITVIEARQLAGANINPLIEVRIGEKTKTTEVQMSTNSPYYNQYLCFEFHMSKAELFDQVIRLRCLAMGNMAIS-RLLPGDLIGEFRMDVRTVYNAPDHMFLHKWAMLVDPKDILSGAKGYVKVDLTIMGKGEQVKHKPKSATKKPKDNDDED---IEANLLLPQTIKTGTKRQMAEICVKIYKAEDLPRMNTDIMATIKMAITGDSKPLVDPFVQVSFAGHTGRTKVKKNTYTPEWNEEIVFTEMFPTLCNRIRVSVYDWDTVFNECIATHYIDLSQIMNEG---DTGFLPTFGPSWVNLYGTPRNYTYDQMMRPKEELNRGLGEGVAYRGRLLIAIKTVLRSESGGLPAGAKVYSVPPISDGTCGKKEPFLLIGAFYEASVIDSEIGKKKQPIYFELSVGTTGNRLDSEANEEEEKEVPSVNQGNRPKIPKWCHSTTEPMLPDTNDQEYFHLSFNEKKPCLYMISYHEDHKSRDFIPNILEKLKNEFSNAV-EILHELHMNERRGTHLRMKNALDTFIENIESSLNSIKCVRHVSPKTLLDKERIKLTKVCLEKMRVKAKTMYQDCTKANLAIRLKECRAIIKKLNELIPNPQNGLPDIFIWLIQDTKRMAFARIPAREILYSAIPEEKGVKNSEVVTVFLQKPGRFGMG-PSGWTLQGQLKMYLWLGLLRDMKTFQQGLPLGYSNDCFKFRRPPMEIIYTEKSYFQLRAHMFMARNLIGSDESGLSDAFARILVNDHVVTTKVVYETLSPKWDQTLIIDHMIFYYSKDLIMSNPPVLVVEMFDEDQMGKSEFLGRCFCKPTVALEEEEYKSPRLTWWEIYRGQMNAGELLAAFELIQVFPDEGYRLANGIPRIEQMIRSSSPIGSLRSNSVFSQKELLLANMEGDINGDITPNEGVTVTAEGHFVVPVPKEIRPSLVPYRVEFLFWGVREMQRVQLMS----------------VDKPRITIEFGSSHLISDVIPSCKVKPNFSNPLKYMDIMLPENLLYWPPLMIQCEDLRQFGRTILIGNHVISNVTKYVIKGKIPTEEPAKKVITNTSSPNQQNNLETPEDKIAIPAIIEGVDNPAYIDDETTAAGNLSSARKSSTN 1295          

Query: 4325 IERIMMYPCELENVKDFGGFHDPFKSFSLYRGKQEEDDDNFENPDRFGGVFKGNICIYNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLRLYKNLRDINPVDFVVRVYIIKAINLHPSDLNGKSDPYILVKLGDKEVRDRENYIPKTLNPVFGKCIELEVTFPQESFLLVQIYDWDRLTKDDLIGETTIDLENRWLSPHQGSCGIMPSYHNHGYLKWKDYRLPTIILKSLCEEHNVPLPIYDKLTDRVDIDDRSFFAETMIEDDDGSQIKSLEPLALEVLHHWHEIVPGKKLVPEYIETRPLYMPEKPGIQQGLLEMWVDMYPAG-TAIPAPIDITPRKAIGYELRCTVIQTEKVRLINVNFFTNEKTVDIFVKSWMKSTDIDLQKTDVHYKSLSGQGLFNWRFVYNFDYLKAEDCIVYTQK-SVYEIDECEYKTPCFLNMQVLDSGIIMSDTIIGKFKCRLSKFPQPAKFYRSCDPFQLSE--ACAKFNLFRNKKVRGWWPLIY----NPKXXXXXXXXXXXXXXCVELEMELVTAEEAESNPVGLGRAEPMPLEAPMRPDGSFLSFLNPWNTIKYFIKYRLKWILIKXXXXXXXXXXXXXXXYNFPGSISNAIV 6214
            IER  +YPC LE VK+F GF    ++F L +G+Q++D+++ +N  R  G FKGN+ IY +D E+     D                                        L LYK+L + +PV  +VR+Y+I+A +LHP+D NGKSDPY+L++LG+K + ++ENYIPK LNP+FGKC EL+V FPQES LL+Q+ DWD ++ DD+IGET IDLENR+ S H+  CG+   + NHGY KW+D +LPT++L  LC+E+    P Y+ L ++V + + +F+A+  IE+D+G + +S EPLALEV+ +W ++  G  LVPE++ETRPL+  EKPGIQQG LEMW+DM+P    A P PIDI PR+ I YELR  +  TE V L +    T EK+ DIFVK WMK   ID Q TDVHY+SLSG+G FNWRF++NFDY+KAED IVY  K S + IDE E K+PC L +QV D+ ++ +D  +G  +  LSK P+ AK  ++C   QL++  + +  ++F+NK+ RGWWP       +PK+ D + +        ++ E +L++ EE E+ PVGLGR EP  L +P RPD SFL+F+NP  ++KY I  + KW LIK  +I   L ++ LFIYN PG ++  ++
Sbjct: 1562 IERFKVYPCPLEEVKEFEGFAAFIQTFPLQKGRQDDDEESSDN--RIVGNFKGNLNIYKVDDEEFGVEVDVH-------------------------------------KLMLYKSLPNNDPVQILVRIYVIRANDLHPADPNGKSDPYLLLRLGNKVINEKENYIPKQLNPIFGKCFELDVKFPQESNLLIQVMDWDLVSGDDIIGETKIDLENRYYSKHKALCGLGQIFENHGYNKWRDIQLPTMMLAKLCKEYGFDPPKYEALVNKVTVAEVAFYADAEIEEDNGEKKQSNEPLALEVMKNWSKVPNGCLLVPEHMETRPLFNSEKPGIQQGSLEMWIDMFPKELGAPPLPIDIAPRQPISYELRVIIWNTEDVILSDGGVLTGEKSSDIFVKGWMKGLGIDDQVTDVHYRSLSGEGNFNWRFIFNFDYIKAEDKIVYKIKDSPFAIDETEIKSPCKLYLQVWDADLVTADDFLGGLELILSKIPRGAKSPQTCGLHQLNKDGSVSTISIFKNKRYRGWWPFTGENEDDPKELDVNGK--------LDAEFQLLSKEEGEACPVGLGRNEPNALPSPNRPDSSFLNFMNPLKSLKYLICNKFKWFLIKALIISALLALLVLFIYNAPGYLAKRML 2152