Inhibitor of growth protein

Overview


Name	Inhibitor of growth protein
Smed ID	SMED30000147
Length (bp)	1304

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Inhibitor of growth protein (SMED30000147) t-SNE clustered cells

Violin plots show distribution of expression levels for Inhibitor of growth protein (SMED30000147) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Inhibitor of growth protein (SMED30000147) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Inhibitor of growth protein (SMED30000147) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30000147

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
posterior side	SMED30000147	SMESG000056794.1	dd_Smed_v4_2936_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior muscle cell	SMED30000147	SMESG000056794.1	dd_Smed_v4_2936_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Inhibitor of growth protein vs. Ensembl Human
Match: ING3 (inhibitor of growth family member 3 [Source:HGNC Symbol;Acc:HGNC:14587])

HSP 1 Score: 93.5893 bits (231), Expect = 2.803e-20
Identity = 42/86 (48.84%), Postives = 53/86 (61.63%), Query Frame = 2

Query: 1046 TIQQISQDSQMNLDNDM-----LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
             +Q+ISQ + +  ++D        +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG W+C  C T   +RRG
Sbjct:  316 VVQEISQQTTVVPESDSNSQVDWTYDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC-TAAMKRRG 399

HSP 2 Score: 57.7658 bits (138), Expect = 1.898e-8
Identity = 33/94 (35.11%), Postives = 53/94 (56.38%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQV-----QEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N M+ L+ R++EFF    +N     ++      ++Y K L++ DE       K+ +  Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct:   19 NAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADE-------KVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 105

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Human
Match: ING3 (inhibitor of growth family member 3 [Source:HGNC Symbol;Acc:HGNC:14587])

HSP 1 Score: 93.9745 bits (232), Expect = 2.884e-20
Identity = 42/86 (48.84%), Postives = 53/86 (61.63%), Query Frame = 2

Query: 1046 TIQQISQDSQMNLDNDM-----LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
             +Q+ISQ + +  ++D        +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG W+C  C T   +RRG
Sbjct:  331 VVQEISQQTTVVPESDSNSQVDWTYDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC-TAAMKRRG 414

HSP 2 Score: 57.3806 bits (137), Expect = 1.283e-13
Identity = 33/94 (35.11%), Postives = 53/94 (56.38%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQV-----QEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N M+ L+ R++EFF    +N     ++      ++Y K L++ DE       K+ +  Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct:   34 NAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADE-------KVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120

HSP 3 Score: 38.891 bits (89), Expect = 1.283e-13
Identity = 15/32 (46.88%), Postives = 24/32 (75.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP + ++  T +R++DLQ+
Sbjct:    1 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Human
Match: ING5 (inhibitor of growth family member 5 [Source:HGNC Symbol;Acc:HGNC:19421])

HSP 1 Score: 82.0333 bits (201), Expect = 3.288e-17
Identity = 31/63 (49.21%), Postives = 40/63 (63.49%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            +  D NE   YC C+ VSYG+MI CD   CP EWFH+ CV+L   PKG WFC  C  + R+++
Sbjct:  179 MPVDPNEPT-YCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK 240

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Human
Match: ING1 (inhibitor of growth family member 1 [Source:HGNC Symbol;Acc:HGNC:6062])

HSP 1 Score: 79.337 bits (194), Expect = 1.959e-16
Identity = 32/59 (54.24%), Postives = 37/59 (62.71%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKN 1273
            L  D NE   YC CN VSYG+MI CD   CP EWFH+ CV L   PKG W+C  C+ +N
Sbjct:  134 LPIDPNEPT-YCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGEN 191

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Human
Match: ING1 (inhibitor of growth family member 1 [Source:HGNC Symbol;Acc:HGNC:6062])

HSP 1 Score: 79.337 bits (194), Expect = 3.144e-16
Identity = 32/59 (54.24%), Postives = 37/59 (62.71%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKN 1273
            L  D NE   YC CN VSYG+MI CD   CP EWFH+ CV L   PKG W+C  C+ +N
Sbjct:  159 LPIDPNEPT-YCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGEN 216

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Celegans
Match: ing-3 (Inhibitor of growth protein [Source:UniProtKB/TrEMBL;Acc:Q9XWJ8])

HSP 1 Score: 78.1814 bits (191), Expect = 2.175e-15
Identity = 25/54 (46.30%), Postives = 34/54 (62.96%), Query Frame = 2

Query: 1106 DTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKT 1267
            D  +E+ +CFCN+ SYGDM+ CD   C   WFHY C+ +V  P G W+C  C+ 
Sbjct:  423 DEEDEMHWCFCNEKSYGDMVQCDNRHCTLRWFHYPCIGMVEPPTGKWYCPRCEV 476

HSP 2 Score: 51.2174 bits (121), Expect = 2.704e-10
Identity = 36/106 (33.96%), Postives = 54/106 (50.94%), Query Frame = 2

Query:  173 LNEFFQKCSQNTLSVSQQVQEYEKILKE-FDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIELMVNQQMKSGVTDGIPRVERKRMKR 487
            +N+FF++   N     +Q +E  K+L+E F  +      K  I E+M++   K    L+ E   F+ E+EADN G  E IE    Q ++S +T    R ERKR  R
Sbjct:   43 INDFFERTGVNM--PEEQRKERCKVLQEEFSTIRVLAQRKYLIAEKMQELLKKYKVHLEKEKTTFQCEMEADNSGVTEMIEKRYTQHVESLLTA---RKERKRRHR 143

HSP 3 Score: 32.7278 bits (73), Expect = 2.704e-10
Identity = 13/32 (40.62%), Postives = 23/32 (71.88%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            ML+ +DF+E +++LP E KE    IR++D ++
Sbjct:    1 MLFLDDFLEMLDELPAELKERSDEIRRIDNEV 32

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BLAST of Inhibitor of growth protein vs. Ensembl Celegans
Match: Y43H11AL.1 (pep chromosome:WBcel235:II:222704:223799:-1 gene:WBGene00021545.1 transcript:Y43H11AL.1e.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y43H11AL.1)

HSP 1 Score: 58.5362 bits (140), Expect = 4.705e-11
Identity = 21/51 (41.18%), Postives = 32/51 (62.75%), Query Frame = 2

Query: 1115 EELRYCFCN--DVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDC 1261
            E+  +C CN  +++ G M+ C+   CP +WFH+ CV L+ AP   W+C DC
Sbjct:   14 EQEEWCICNGMNINSGMMVECENKNCPIKWFHFECVGLLAAPLDEWYCTDC 64

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Celegans
Match: Y43H11AL.1 (pep chromosome:WBcel235:II:222704:228035:-1 gene:WBGene00021545.1 transcript:Y43H11AL.1e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y43H11AL.1)

HSP 1 Score: 58.5362 bits (140), Expect = 4.705e-11
Identity = 21/51 (41.18%), Postives = 32/51 (62.75%), Query Frame = 2

Query: 1115 EELRYCFCN--DVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDC 1261
            E+  +C CN  +++ G M+ C+   CP +WFH+ CV L+ AP   W+C DC
Sbjct:   14 EQEEWCICNGMNINSGMMVECENKNCPIKWFHFECVGLLAAPLDEWYCTDC 64

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Celegans
Match: Y43H11AL.1 (pep chromosome:WBcel235:II:222704:230070:-1 gene:WBGene00021545.1 transcript:Y43H11AL.1d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y43H11AL.1)

HSP 1 Score: 59.6918 bits (143), Expect = 2.027e-10
Identity = 32/97 (32.99%), Postives = 49/97 (50.52%), Query Frame = 2

Query:  983 SRTPGSLN--FGMYSEPMISGSNTIQQISQDSQMNLDNDMLGFDTNEELRYCFCN--DVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDC 1261
            S TP   N  FG  S+   SG    +   + ++M + N        E+  +C CN  +++ G M+ C+   CP +WFH+ CV L+ AP   W+C DC
Sbjct:   66 SHTPPQRNTLFGSISDTSFSGRPR-KLTDRVTEMIISNRERTKKYREQEEWCICNGMNINSGMMVECENKNCPIKWFHFECVGLLAAPLDEWYCTDC 161

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Celegans
Match: Y43H11AL.1 (pep chromosome:WBcel235:II:222704:232029:-1 gene:WBGene00021545.1 transcript:Y43H11AL.1c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y43H11AL.1)

HSP 1 Score: 62.3882 bits (150), Expect = 2.626e-10
Identity = 32/97 (32.99%), Postives = 49/97 (50.52%), Query Frame = 2

Query:  983 SRTPGSLN--FGMYSEPMISGSNTIQQISQDSQMNLDNDMLGFDTNEELRYCFCN--DVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDC 1261
            S TP   N  FG  S+   SG    +   + ++M + N        E+  +C CN  +++ G M+ C+   CP +WFH+ CV L+ AP   W+C DC
Sbjct:  377 SHTPPQRNTLFGSISDTSFSG-RPRKLTDRVTEMIISNRERTKKYREQEEWCICNGMNINSGMMVECENKNCPIKWFHFECVGLLAAPLDEWYCTDC 472

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BLAST of Inhibitor of growth protein vs. Ensembl Fly
Match: Ing3 (gene:FBgn0030945 transcript:FBtr0074614)

HSP 1 Score: 90.1225 bits (222), Expect = 5.215e-19
Identity = 36/62 (58.06%), Postives = 42/62 (67.74%), Query Frame = 2

Query: 1103 FDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
            +D NE  RYC CN VSYGDM+ACD   CP EWFHY CV +   PKG W+C  C T + +RRG
Sbjct:  623 YDPNEP-RYCTCNQVSYGDMVACDNDACPYEWFHYPCVGITQPPKGKWYCPKC-TASMRRRG 682

HSP 2 Score: 62.003 bits (149), Expect = 1.837e-15
Identity = 31/89 (34.83%), Postives = 52/89 (58.43%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQVQEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N M+ LD + + FF++C ++ L       E+  +  E+ +V     +K+AI  Q+ +   + +++LD+EL KFK ELEADN G  E +E
Sbjct:   34 NNMDSLDKKAHMFFKQCKRDELQHESMDTEFHSLRGEYFKVMEDADEKVAIATQIHELVERYLRRLDSELFKFKCELEADNNGITEILE 122

HSP 3 Score: 39.6614 bits (91), Expect = 1.837e-15
Identity = 16/32 (50.00%), Postives = 23/32 (71.88%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP E ++  T +R+LDL +
Sbjct:    1 MLYLEDYLEMIEHLPQELRDRFTEMRELDLAV 32

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Fly
Match: Ing5 (gene:FBgn0032516 transcript:FBtr0080525)

HSP 1 Score: 80.1073 bits (196), Expect = 1.536e-16
Identity = 29/53 (54.72%), Postives = 37/53 (69.81%), Query Frame = 2

Query: 1127 YCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            YC C+ VSYG+MI CD   CP EWFH+ CV L   PKG WFC  C T++R+++
Sbjct:  234 YCLCHQVSYGEMIGCDNPDCPIEWFHFACVGLTTKPKGKWFCPKC-TQDRKKK 285

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Fly
Match: Ing5 (gene:FBgn0032516 transcript:FBtr0080526)

HSP 1 Score: 79.7221 bits (195), Expect = 1.694e-16
Identity = 29/53 (54.72%), Postives = 37/53 (69.81%), Query Frame = 2

Query: 1127 YCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            YC C+ VSYG+MI CD   CP EWFH+ CV L   PKG WFC  C T++R+++
Sbjct:  220 YCLCHQVSYGEMIGCDNPDCPIEWFHFACVGLTTKPKGKWFCPKC-TQDRKKK 271

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Fly
Match: CG7379 (gene:FBgn0038546 transcript:FBtr0083529)

HSP 1 Score: 80.1073 bits (196), Expect = 6.333e-16
Identity = 28/50 (56.00%), Postives = 37/50 (74.00%), Query Frame = 2

Query: 1115 EELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCK 1264
            +E  YC CN +S+G+MI CD   CP EWFH+ CV+LV+ PKG WFC +C+
Sbjct:  356 DEPTYCVCNQISFGEMILCDNDLCPIEWFHFSCVSLVLKPKGKWFCPNCR 405

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Fly
Match: MESR4 (gene:FBgn0034240 transcript:FBtr0340220)

HSP 1 Score: 69.3218 bits (168), Expect = 3.604e-12
Identity = 25/48 (52.08%), Postives = 32/48 (66.67%), Query Frame = 2

Query: 1127 YCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTK 1270
            YC C      +MIACDG  C  EWFH+ CV ++VAP+G WFC +C+ K
Sbjct: 2092 YCRCPYDEVSEMIACDGDNCLIEWFHFECVGIMVAPQGKWFCAECRPK 2139

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Zebrafish
Match: ing3 (inhibitor of growth family, member 3 [Source:ZFIN;Acc:ZDB-GENE-040109-3])

HSP 1 Score: 92.4337 bits (228), Expect = 5.862e-20
Identity = 37/62 (59.68%), Postives = 42/62 (67.74%), Query Frame = 2

Query: 1103 FDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
            +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG W+C  C T   +RRG
Sbjct:  353 YDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC-TAAMKRRG 412

HSP 2 Score: 60.077 bits (144), Expect = 1.490e-14
Identity = 35/94 (37.23%), Postives = 52/94 (55.32%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQVQE-----YEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N M+ L+ R+NEFF    +N     ++  E     Y K L++ DE       K+ +  Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct:   34 NAMDQLEQRVNEFFTNAKKNKPEWREEQMEIIKKDYYKALEDADE-------KVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120

HSP 3 Score: 38.891 bits (89), Expect = 1.490e-14
Identity = 15/32 (46.88%), Postives = 24/32 (75.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP + ++  T +R++DLQ+
Sbjct:    1 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Zebrafish
Match: ing5a (inhibitor of growth family, member 5a [Source:ZFIN;Acc:ZDB-GENE-031016-1])

HSP 1 Score: 80.8777 bits (198), Expect = 6.737e-17
Identity = 32/63 (50.79%), Postives = 42/63 (66.67%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            +  D NE   YC C+ VSYG+MI CD   CP EWFH+ CV+L   PKG WFC  C T++R+++
Sbjct:  182 MPVDPNEPT-YCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRC-TQDRKKK 242

[Close]

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            +  D NE   YC C+ VSYG+MI CD   CP EWFH+ CV+L   PKG WFC  C T++R+++
Sbjct:  182 MPVDPNEPT-YCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRC-TQDRKKK 242

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Zebrafish
Match: ing2 (inhibitor of growth family, member 2 [Source:ZFIN;Acc:ZDB-GENE-040718-147])

HSP 1 Score: 77.0258 bits (188), Expect = 2.207e-15
Identity = 30/57 (52.63%), Postives = 34/57 (59.65%), Query Frame = 2

Query: 1103 FDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKN 1273
             D NE   YC C  VSYG+MI CD   CP EWFH+ CV L   PKG W+C  C+  N
Sbjct:  205 IDPNEPT-YCLCEQVSYGEMIGCDNEQCPIEWFHFSCVGLTYKPKGKWYCPKCRGDN 260

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Zebrafish
Match: ing5b (inhibitor of growth family, member 5b [Source:ZFIN;Acc:ZDB-GENE-030616-462])

HSP 1 Score: 75.8702 bits (185), Expect = 3.425e-15
Identity = 26/45 (57.78%), Postives = 30/45 (66.67%), Query Frame = 2

Query: 1127 YCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDC 1261
            YC C+ VSYG+MI CD   CP EWFH+ CV L   PKG W+C  C
Sbjct:  188 YCLCSQVSYGEMIGCDNSDCPIEWFHFACVGLATKPKGKWYCPRC 232

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
Match: tmem192 (transmembrane protein 192 [Source:Xenbase;Acc:XB-GENE-5751968])

HSP 1 Score: 91.6633 bits (226), Expect = 1.571e-19
Identity = 37/62 (59.68%), Postives = 42/62 (67.74%), Query Frame = 2

Query: 1103 FDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
            +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG W+C  C T   +RRG
Sbjct:  354 YDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLSEAPKGKWYCPQC-TAAMKRRG 413

HSP 2 Score: 56.9954 bits (136), Expect = 1.617e-13
Identity = 33/94 (35.11%), Postives = 52/94 (55.32%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQV-----QEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N M+ L+ R+ EFF    +N     ++      ++Y K L++ DE       K+ +  Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct:   34 NAMDQLEQRVGEFFMNAKKNKPEWREEQMASIKKDYFKALEDADE-------KVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120

HSP 3 Score: 39.2762 bits (90), Expect = 1.617e-13
Identity = 15/32 (46.88%), Postives = 24/32 (75.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP + ++  T +R++DLQ+
Sbjct:    1 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
Match: ccnf (cyclin F [Source:Xenbase;Acc:XB-GENE-963729])

HSP 1 Score: 81.2629 bits (199), Expect = 1.097e-16
Identity = 33/64 (51.56%), Postives = 40/64 (62.50%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
            L  D NE   YC CN VSYG+MI CD   CP EWFH+ CV L   PKG W+C +C+ +N +  G
Sbjct:  203 LPIDPNEPT-YCLCNQVSYGEMIGCDNEECPIEWFHFSCVGLNHKPKGKWYCPECRGENEKTMG 265

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
Match: lman1l (lectin, mannose-binding, 1 like [Source:Xenbase;Acc:XB-GENE-5754170])

HSP 1 Score: 79.337 bits (194), Expect = 2.348e-16
Identity = 32/62 (51.61%), Postives = 40/62 (64.52%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQR 1282
            +  D NE   YC C+ VSYG+MI CD   CP EWFH+ CV+L   PKG WFC  C T+ R++
Sbjct:  177 MPVDPNEPT-YCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRC-TQERKK 236

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
Match: atp2b2 (ATPase, Ca++ transporting, plasma membrane 2 [Source:Xenbase;Acc:XB-GENE-950177])

HSP 1 Score: 77.7962 bits (190), Expect = 1.793e-15
Identity = 31/61 (50.82%), Postives = 36/61 (59.02%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQ 1279
               D NE   YC CN VSYG+MI CD   C  EWFH+ CV L   PKG W+C DC+  N +
Sbjct:  204 FAIDPNEPT-YCLCNQVSYGEMIGCDNDECTIEWFHFSCVGLTYKPKGKWYCPDCRGDNEK 263

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
Match: ING4 (inhibitor of growth family member 4 [Source:NCBI gene;Acc:100491241])

HSP 1 Score: 72.4034 bits (176), Expect = 1.164e-13
Identity = 25/52 (48.08%), Postives = 33/52 (63.46%), Query Frame = 2

Query: 1127 YCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQR 1282
            YC C+ VSYG+MI CD   C  EWFH+ CV L   P+G WFC  C  + +++
Sbjct:  237 YCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLATKPRGKWFCPRCSQEGKKK 288

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Mouse
Match: Ing3 (inhibitor of growth family, member 3 [Source:MGI Symbol;Acc:MGI:1919027])

HSP 1 Score: 94.7449 bits (234), Expect = 9.456e-21
Identity = 42/86 (48.84%), Postives = 53/86 (61.63%), Query Frame = 2

Query: 1046 TIQQISQDSQMNLDNDM-----LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
             +Q++SQ + +  ++D        +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG WFC  C T   +RRG
Sbjct:  323 VVQEVSQQATVVPESDSNSQVDWTYDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWFCPQC-TAAMKRRG 406

HSP 2 Score: 57.7658 bits (138), Expect = 7.103e-14
Identity = 33/94 (35.11%), Postives = 53/94 (56.38%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQV-----QEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N M+ L+ R++EFF    +N     ++      ++Y K L++ DE       K+ +  Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct:   34 NAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADE-------KVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120

HSP 3 Score: 38.891 bits (89), Expect = 7.103e-14
Identity = 15/32 (46.88%), Postives = 24/32 (75.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP + ++  T +R++DLQ+
Sbjct:    1 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Mouse
Match: Ing3 (inhibitor of growth family, member 3 [Source:MGI Symbol;Acc:MGI:1919027])

HSP 1 Score: 94.7449 bits (234), Expect = 1.014e-20
Identity = 42/86 (48.84%), Postives = 53/86 (61.63%), Query Frame = 2

Query: 1046 TIQQISQDSQMNLDNDM-----LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
             +Q++SQ + +  ++D        +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG WFC  C T   +RRG
Sbjct:  334 VVQEVSQQATVVPESDSNSQVDWTYDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWFCPQC-TAAMKRRG 417

HSP 2 Score: 57.7658 bits (138), Expect = 6.759e-14
Identity = 33/94 (35.11%), Postives = 53/94 (56.38%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQV-----QEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N M+ L+ R++EFF    +N     ++      ++Y K L++ DE       K+ +  Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct:   34 NAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADE-------KVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120

HSP 3 Score: 38.891 bits (89), Expect = 6.759e-14
Identity = 15/32 (46.88%), Postives = 24/32 (75.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP + ++  T +R++DLQ+
Sbjct:    1 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Mouse
Match: Ing5 (inhibitor of growth family, member 5 [Source:MGI Symbol;Acc:MGI:1922816])

HSP 1 Score: 82.0333 bits (201), Expect = 2.193e-17
Identity = 31/63 (49.21%), Postives = 40/63 (63.49%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            +  D NE   YC C+ VSYG+MI CD   CP EWFH+ CV+L   PKG WFC  C  + R+++
Sbjct:  179 MPVDPNEPT-YCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK 240

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Mouse
Match: Ing5 (inhibitor of growth family, member 5 [Source:MGI Symbol;Acc:MGI:1922816])

HSP 1 Score: 81.2629 bits (199), Expect = 2.675e-17
Identity = 31/63 (49.21%), Postives = 40/63 (63.49%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            +  D NE   YC C+ VSYG+MI CD   CP EWFH+ CV+L   PKG WFC  C  + R+++
Sbjct:  152 MPVDPNEPT-YCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK 213

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Mouse
Match: Ing2 (inhibitor of growth family, member 2 [Source:MGI Symbol;Acc:MGI:1916510])

HSP 1 Score: 79.337 bits (194), Expect = 3.749e-16
Identity = 31/61 (50.82%), Postives = 37/61 (60.66%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQ 1279
               D NE   YC CN VSYG+MI CD   CP EWFH+ CV+L   PKG W+C  C+  N +
Sbjct:  206 FAIDPNEPT-YCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEK 265

[Close]

BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
Match: sp|Q8VEK6|ING3_MOUSE (Inhibitor of growth protein 3 OS=Mus musculus OX=10090 GN=Ing3 PE=1 SV=2)

HSP 1 Score: 94.7449 bits (234), Expect = 7.093e-20
Identity = 42/86 (48.84%), Postives = 53/86 (61.63%), Query Frame = 2

Query: 1046 TIQQISQDSQMNLDNDM-----LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
             +Q++SQ + +  ++D        +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG WFC  C T   +RRG
Sbjct:  334 VVQEVSQQATVVPESDSNSQVDWTYDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWFCPQC-TAAMKRRG 417

HSP 2 Score: 57.7658 bits (138), Expect = 4.052e-13
Identity = 33/94 (35.11%), Postives = 53/94 (56.38%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQV-----QEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N M+ L+ R++EFF    +N     ++      ++Y K L++ DE       K+ +  Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct:   34 NAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADE-------KVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120

HSP 3 Score: 38.891 bits (89), Expect = 4.052e-13
Identity = 15/32 (46.88%), Postives = 24/32 (75.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP + ++  T +R++DLQ+
Sbjct:    1 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
Match: sp|Q498T3|ING3_RAT (Inhibitor of growth protein 3 OS=Rattus norvegicus OX=10116 GN=Ing3 PE=2 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 8.879e-20
Identity = 42/86 (48.84%), Postives = 53/86 (61.63%), Query Frame = 2

Query: 1046 TIQQISQDSQMNLDNDM-----LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
             +Q++SQ + +  ++D        +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG WFC  C T   +RRG
Sbjct:  334 VVQEVSQQTTVVPESDSNSQVDWTYDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWFCPQC-TAAMKRRG 417

HSP 2 Score: 57.3806 bits (137), Expect = 5.220e-13
Identity = 33/94 (35.11%), Postives = 53/94 (56.38%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQV-----QEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N M+ L+ R++EFF    +N     ++      ++Y K L++ DE       K+ +  Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct:   34 NAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADE-------KVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120

HSP 3 Score: 38.891 bits (89), Expect = 5.220e-13
Identity = 15/32 (46.88%), Postives = 24/32 (75.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP + ++  T +R++DLQ+
Sbjct:    1 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
Match: sp|Q5RBA1|ING3_PONAB (Inhibitor of growth protein 3 OS=Pongo abelii OX=9601 GN=ING3 PE=2 SV=1)

HSP 1 Score: 93.5893 bits (231), Expect = 1.359e-19
Identity = 42/86 (48.84%), Postives = 53/86 (61.63%), Query Frame = 2

Query: 1046 TIQQISQDSQMNLDNDM-----LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
             +Q+ISQ + +  ++D        +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG W+C  C T   +RRG
Sbjct:  316 VVQEISQQTTVVPESDSNSQVDWTYDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC-TAAMKRRG 399

HSP 2 Score: 56.9954 bits (136), Expect = 1.742e-7
Identity = 33/94 (35.11%), Postives = 52/94 (55.32%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQV-----QEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N M+ L+ R +EFF    +N     ++      ++Y K L++ DE       K+ +  Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct:   19 NAMDQLEQRASEFFMNAKKNKPEWREEQMASIKKDYYKALEDADE-------KVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 105

[Close]

BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
Match: sp|Q9NXR8|ING3_HUMAN (Inhibitor of growth protein 3 OS=Homo sapiens OX=9606 GN=ING3 PE=1 SV=2)

HSP 1 Score: 93.9745 bits (232), Expect = 1.385e-19
Identity = 42/86 (48.84%), Postives = 53/86 (61.63%), Query Frame = 2

Query: 1046 TIQQISQDSQMNLDNDM-----LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
             +Q+ISQ + +  ++D        +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG W+C  C T   +RRG
Sbjct:  331 VVQEISQQTTVVPESDSNSQVDWTYDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC-TAAMKRRG 414

HSP 2 Score: 57.3806 bits (137), Expect = 5.573e-13
Identity = 33/94 (35.11%), Postives = 53/94 (56.38%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQV-----QEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N M+ L+ R++EFF    +N     ++      ++Y K L++ DE       K+ +  Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct:   34 NAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADE-------KVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120

HSP 3 Score: 38.891 bits (89), Expect = 5.573e-13
Identity = 15/32 (46.88%), Postives = 24/32 (75.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP + ++  T +R++DLQ+
Sbjct:    1 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
Match: sp|Q5ZK36|ING3_CHICK (Inhibitor of growth protein 3 OS=Gallus gallus OX=9031 GN=ING3 PE=2 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 6.594e-19
Identity = 37/62 (59.68%), Postives = 42/62 (67.74%), Query Frame = 2

Query: 1103 FDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
            +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG W+C  C T   +RRG
Sbjct:  354 YDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC-TAAMKRRG 413

[Close]

BLAST of Inhibitor of growth protein vs. TrEMBL
Match: A0A5N4AAI4 (Uncharacterized protein OS=Photinus pyralis OX=7054 GN=PPYR_11166 PE=4 SV=1)

HSP 1 Score: 136.346 bits (342), Expect = 2.456e-33
Identity = 110/388 (28.35%), Postives = 165/388 (42.53%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQV-QEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAE-----TIELMVNQ--QMKSGVTDGIPRVERKRMKRGRLAFDSNISLQPNSESTRKIIRPKDTTESFSYKSEKIDGFGSISGQSDTLMTTAVANGSLSPASSFMGSLNTPHSIKRKFDWKQASSISTDKLVKSERKRQKIMSALSEDSGSNLGANDEFGLDEXXXXXXXXXXXXXXXXXXXEPDTNPRKSVPNDGMSDGGSSRTPGSLNFGMYSEPMISGSNTIQQISQDSQMNLDNDM-LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQR 1282
            N +E L+ R+  FF  C +    + Q    E++ I KE+ +   +  +K+ +  QM +  +K +++LDTEL+KFK ELEADN G  E     ++EL   Q  Q  S       R ER+   R     DS  SLQ                 SF+ K + I     +  + +T  T  VA  +  P  S+    N  H          AS          + +R   + A  E   + +  N EFG+      ++               +   +K     G S   +  T  ++   + + P++S +    Q+    Q+    +    +D NE  RYC CN VSYGDM+ACD   CP EWFHY CV +   PKG W+C  C T  R+R
Sbjct:   34 NNLEELEKRVRIFFSDCKRYQSEIPQSSDNEFQDIRKEYYKTLEEADEKVHLANQMYELVDKYLRRLDTELHKFKCELEADNKGITEVLEKRSLELDTPQLGQTLSSSQQKENRFERETRPRAEKRRDSGSSLQ----------------TSFAEKRQAIAPVAVVETRHNT--TPQVATTTPQPTVSY----NISHIGAGPAIAAAASQAIAATQQMQQGRRTASLKASYEAINTGVHVN-EFGIGRELAGAAQTAIQAIQQDHN---NKKKQKKWTGSGSSTSNNVNTVSTVQAILSTPPVVSPAPASPQVETTVQVADGGEADWTYDPNEP-RYCICNQVSYGDMVACDNEDCPSEWFHYPCVGITAPPKGKWYCPQCTTSMRRR 394

HSP 2 Score: 36.5798 bits (83), Expect = 2.456e-33
Identity = 14/32 (43.75%), Postives = 23/32 (71.88%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP E ++  + +R++DL +
Sbjct:    1 MLYLEDYLEMIEHLPQELRDRFSEMREMDLSV 32

[Close]

BLAST of Inhibitor of growth protein vs. TrEMBL
Match: A0A2P6K8Y4 (Inhibitor of growth protein OS=Nephila clavipes OX=2585209 GN=NCL1_48210 PE=3 SV=1)

HSP 1 Score: 129.798 bits (325), Expect = 2.521e-32
Identity = 110/397 (27.71%), Postives = 178/397 (44.84%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQVQEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAE-----TIELMVNQQMKSGVTDGIPRVERKRMKRGRLAFDSNISLQPNSESTRKIIRPKDTTESFSYKSEKIDGFGSISGQSDTLMTTAVANGS---LSPAS--SFMGS-----LNTPHSIKRKFDWKQASSISTDKLVKSERKRQKIMSAL-SEDSGSNLGANDEFGLDEXXXXXXXXXXXXXXXXXXXEPDTNPRKSVPNDGMSDGGSSRTPGSLNFGMYSEPMISGSNTIQQISQDSQMNLDNDML--GFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQR 1282
            N M+ LD R+  FF    +  L   ++  EYEKI  ++ +      +K+ I  Q+ D   + +++LD EL KFK+ELEADN G  E     ++EL       + ++   PR E+++  +  L+       Q  +E     I  +   E+       + G    S  + +  + + A      L+P +  +F+G+       +      +   K+ +S S   LV+  R+   + ++  + +SG NL      G  E  +  +   N  +     SEP    +K+  N                  +  +P+I  S  ++  S+DS + LD +M    +D NE  RYC CN VSYGDM+ACD   CP EWFHY CV +   PKG WFC  C    ++R
Sbjct:   34 NAMDSLDERVKNFFPNAKK--LKPIERDTEYEKIRVDYYKALEDADEKVHIANQVYDLVERYLRRLDQELQKFKMELEADNAGITEILEKRSLELDNPPPTTNSMSSSYPRGEKRKHGQANLSVSYTPDKQLTAEKVFSTIATEAMRETIGGSRVTLPGHSPSSSSTSSSSSNSSAQERTIVLNPQTKNTFVGTNALAAAASQAIAATQQSLKRGTSQSQSNLVQQGRRTASLKASYEAVNSGQNLNKELTLGSREINSVVAAPTNIASAVTMPSEPKKVTKKARSN------------------LIIQPVIEPSPLLED-SEDSSV-LDENMFIDSYDPNEP-RYCICNQVSYGDMVACDHKDCPFEWFHYQCVGITQPPKGKWFCPQCSASMKRR 407

HSP 2 Score: 39.6614 bits (91), Expect = 2.521e-32
Identity = 16/32 (50.00%), Postives = 24/32 (75.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP E ++  T +R++DLQ+
Sbjct:    1 MLYLEDYLEMIEHLPQELRDRFTEMREMDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. TrEMBL
Match: K1PV61 (Inhibitor of growth protein OS=Crassostrea gigas OX=29159 GN=CGI_10019481 PE=3 SV=1)

HSP 1 Score: 133.65 bits (335), Expect = 2.883e-31
Identity = 108/409 (26.41%), Postives = 177/409 (43.28%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQVQEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIELMVNQQMKSGVTDGIPRVERKRMKRG----------RLAFDSNISLQPNSESTRKIIRPKD------------------TTESFSYKSEKIDGFGSISGQSDTLMTTAVANGSLSPASSFMGSLNTPHSIKRKFDWKQASSISTDKLVKSERKRQKIMSALSEDSGSNLGANDEFGLDEXXXXXXXXXXXXXXXXXXXEPDTNPRKSVPNDGMSDGGSSRTPGSLNFGMYSEPMISGSNTIQQISQDSQMNLDNDMLGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
            N ++ LD R+  FF+KC+Q  +    + ++Y++I +++ +      +K+ +   + D  ++ ++KLD EL+KFK+ELEADN G  E +E   + ++    + G  R E++++             R+A +  +S   N E+ R+ I                      +T+S SY  EK D  G    ++ ++  + VA      A      L+T   I               + V   +K     S L  ++ + L ++                                  S+P+  ++   S  TP +      + PM+  +++  QI  ++   +D      D NE  RYC CN VSYGDM+ CD   CP EWFHYGCV L  APKG WFC  C T   +RRG
Sbjct:   35 NALDNLDERVKNFFKKCTQPNIKGELKDEQYKQIKQDYYKTLEDADEKVQLANHIYDLVDRHLRKLDQELSKFKMELEADNAGITEVLE-KRSLELDKPPSLGSNRAEKRKLLHAQSQVTNHTEKRMATEKVLSTIAN-EAAREAIGQSRRQSSSGSNSPSLSMFNSTSTQSISYSLEKCDHMGQQGRRTPSMKASYVAM-----AKDLTKELSTKEYIYTSQPSTPTPVAEITQKVPRSKKATSKASTLIREAQNQLASS----------------------------------SIPSLSLTQQPS--TPQTPLSAQVASPMVEDASSDLQIVDENGQPVD---WQNDPNEP-RYCLCNQVSYGDMVGCDNDDCPIEWFHYGCVGLTQAPKGKWFCPQC-TAAIKRRG 395

[Close]

BLAST of Inhibitor of growth protein vs. TrEMBL
Match: A0A4Y2F1K6 (Inhibitor of growth protein OS=Araneus ventricosus OX=182803 GN=Ing3 PE=3 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 1.728e-30
Identity = 108/397 (27.20%), Postives = 176/397 (44.33%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQVQEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAE-----TIELMVNQQMKSGVTDGIPRVERKRMKRGRLAFDSNISLQPNSESTRKIIRPKDTTESFSYKSEKIDGFGSIS-----------GQSDTLMTTAVANGSLSPASSFMGSLNTPHSIKRKFDWKQASSISTDKLVKSERKRQKIMSAL-SEDSGSNLGANDEFGLDEXXXXXXXXXXXXXXXXXXXEPDTNPRKSVPNDGMSDGGSSRTPGSLNFGMYSEPMISGSNTIQQISQDSQMNLDNDML-GFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQR 1282
            N ++ LD R+  FF    +  +  S++  EYEKI  ++ +      +K+ I  Q+ D   + +++LD EL KFK+ELEADN G  E     ++EL       + ++   PR E+++  +  ++       Q  SE     I  +   E+ S     + G    S            Q  T++ T     +   +++ + +  +      +   K+ +S +   LV+  R+   + ++  + +SG NL      G  E  +  +   N  N     SEP    +K+            RT       M  +P+   S  ++  S+DS +  +N  L  +D NE  RYC CN VSYGDM+ACD   CP EWFHY CV +   PKG WFC  C    ++R
Sbjct:   34 NTVDSLDERVKVFFSNAKK--MKQSERDCEYEKIRLDYYKALEDADEKVHIANQVYDLVERYLRRLDQELQKFKMELEADNAGITEILEKRSLELDNPPPTSNSISTNYPRGEKRKHGQQNISVSYTPDKQIASEKVFSTIATEAMRETISGNRVALPGHSPSSSSTSSSSSNSSAQERTIVLTPQTKSTFV-STNALAAAASQAIAATQQSLKRGTSQNQSNLVQQGRRTASLKASYEAVNSGQNLNKELTLGSREINSVVTAPTNIANSVTVPSEPKKVSKKA------------RT------SMVVQPVAEPSPLLED-SEDSSVLEENMFLDNYDPNEP-RYCVCNQVSYGDMVACDHKDCPFEWFHYQCVGITQPPKGKWFCPQCSASMKRR 407

HSP 2 Score: 39.6614 bits (91), Expect = 1.728e-30
Identity = 16/32 (50.00%), Postives = 24/32 (75.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP E ++  T +R++DLQ+
Sbjct:    1 MLYLEDYLEMIEHLPQELRDRFTEMREMDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. TrEMBL
Match: A0A1J1HNQ8 (Inhibitor of growth protein OS=Clunio marinus OX=568069 GN=CLUMA_CG003431 PE=3 SV=1)

HSP 1 Score: 120.168 bits (300), Expect = 3.543e-29
Identity = 105/400 (26.25%), Postives = 195/400 (48.75%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQVQEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIELMVNQQMK-SGVTDGIPRVERKRMKRGRLAFDSNISLQPNSESTRKIIRPKDTTESFSYKSEKIDGFGSISG-----QSDTLMTTAVANGSLSPAS-SFMGSLNTPHSIKRKFDWKQASSISTDKLVKSE-----RKRQKIMSALSEDSGSNLGANDEF-GLD-EXXXXXXXXXXXXXXXXXXXEPDTNPR---KSVPNDGMSDGGSSRTPGSLNFGMYSEPMISGSNTIQQISQDSQMNLDNDMLG---FDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            N  + +D ++  FF +C +  L+      ++E I K++++V   + +K+ +  Q+ +  ++ +++LDTEL KFK ELEADN G     EL+  + ++  G + G+ + E +                  S S+ ++    D TE + +K EK    G+ S      +    +++ +   +L PA+ +    L +  S+    +    +  +   + K++     R+   + ++     GS +  ++   G D  ++++   ++  V+ + + S  + NP+   K + + GM    S +T GSL   + +    S       I++D  M ++    G   +D NE  RYC CN VSYG+M+ACD   CP EWFHY CV +  +PKG W+C  C TKNR+++
Sbjct:   34 NDTDTIDKQIRNFFGQCRRGELNGIHADAQFESIKKDYEKVREDSDEKVQLANQIYELVDRYLRRLDTELLKFKCELEADNHG---ITELLEKRSLELDGSSSGVNQKENRYF---------------GSLSSNRV----DRTERYRHKVEKRRDSGTPSQLGAPPEKRQPISSGLTTPTLRPATPNLTQVLQSNPSVSYTGNATIIAQAAAQAIEKTQQMQQGRRTASLKASYEAIHGSGMNTHELLMGRDLSASHALQSMDRDVSFASTASGSNNNPKRYKKKINSIGMGSSQSPQTTGSLLHQLQTHSNDSDEMPSSYINKDG-MVVEQTADGEWTYDPNEP-RYCICNQVSYGEMVACDNAECPLEWFHYPCVGITTSPKGKWYCPMC-TKNRKKK 408

HSP 2 Score: 38.5058 bits (88), Expect = 3.543e-29
Identity = 16/32 (50.00%), Postives = 23/32 (71.88%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP E ++  T +R+LDL +
Sbjct:    1 MLYLEDYLEMIEHLPQELRDRFTEMRELDLSV 32

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
Match: ing3 (inhibitor of growth family member 3 [Source:NCBI gene;Acc:103046788])

HSP 1 Score: 92.0485 bits (227), Expect = 6.425e-20
Identity = 37/62 (59.68%), Postives = 42/62 (67.74%), Query Frame = 2

Query: 1103 FDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
            +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG W+C  C T   +RRG
Sbjct:  355 YDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC-TAAMKRRG 414

HSP 2 Score: 60.4622 bits (145), Expect = 9.734e-15
Identity = 35/94 (37.23%), Postives = 52/94 (55.32%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQVQE-----YEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N M+ L+ R+NEFF    +N     ++  E     Y K L++ DE       K+ +  Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct:   34 NAMDQLEQRVNEFFANAKKNKPEWREEQMEVIKKDYYKALEDADE-------KVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120

HSP 3 Score: 38.891 bits (89), Expect = 9.734e-15
Identity = 15/32 (46.88%), Postives = 24/32 (75.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP + ++  T +R++DLQ+
Sbjct:    1 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
Match: ing5a (inhibitor of growth family member 5 [Source:NCBI gene;Acc:103024432])

HSP 1 Score: 80.1073 bits (196), Expect = 1.047e-16
Identity = 32/63 (50.79%), Postives = 42/63 (66.67%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            +  D NE   YC C+ VSYG+MI CD   CP EWFH+ CV+L   PKG WFC  C T++R+++
Sbjct:  181 MPVDPNEPT-YCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRC-TQDRKKK 241

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
Match: ing5b (inhibitor of growth protein 5-like [Source:NCBI gene;Acc:103037104])

HSP 1 Score: 79.337 bits (194), Expect = 1.511e-16
Identity = 28/52 (53.85%), Postives = 34/52 (65.38%), Query Frame = 2

Query: 1127 YCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQR 1282
            YC C+ VSYG+MI CD   CP EWFH+ CV+L   PKG WFC  C    R++
Sbjct:  184 YCLCSQVSYGEMIGCDNADCPIEWFHFACVDLTTKPKGEWFCPRCVLDMRKK 235

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
Match: ing1 (inhibitor of growth protein 1-like [Source:NCBI gene;Acc:103047717])

HSP 1 Score: 77.411 bits (189), Expect = 1.944e-15
Identity = 31/61 (50.82%), Postives = 37/61 (60.66%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQ 1279
            L  D NE   YC C  VSYG+MI CD   CP EWFH+ CV L   PKG W+C  C+ +N +
Sbjct:  234 LPIDPNEPT-YCLCEQVSYGEMICCDNDKCPIEWFHFSCVGLHHKPKGKWYCPKCRGENEK 293

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
Match: ing2 (inhibitor of growth family member 2 [Source:NCBI gene;Acc:103031897])

HSP 1 Score: 76.6406 bits (187), Expect = 2.596e-15
Identity = 27/49 (55.10%), Postives = 31/49 (63.27%), Query Frame = 2

Query: 1127 YCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKN 1273
            YC C  VSYG+MI CD   CP EWFH+ CV L   PKG W+C  C+  N
Sbjct:  214 YCLCEQVSYGEMIGCDNEQCPIEWFHFSCVGLTYKPKGRWYCPKCRGDN 262

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000234.1 (pep scaffold:Pmarinus_7.0:GL482739:14:2848:1 gene:ENSPMAG00000000213.1 transcript:ENSPMAT00000000234.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 83.9593 bits (206), Expect = 9.260e-20
Identity = 41/88 (46.59%), Postives = 52/88 (59.09%), Query Frame = 2

Query: 1040 SNTIQQISQDSQMNLDNDM-----LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
            S   Q+++Q   +  D ++       +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG W+C  C T   +RRG
Sbjct:   53 SALAQELAQPDMVIADAELSDQVDWTYDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLKEAPKGKWYCPQC-TVAMKRRG 138

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008794.1 (pep scaffold:Pmarinus_7.0:GL476329:1735629:1740570:1 gene:ENSPMAG00000007965.1 transcript:ENSPMAT00000008794.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.6406 bits (187), Expect = 5.231e-17
Identity = 31/55 (56.36%), Postives = 35/55 (63.64%), Query Frame = 2

Query: 1115 EELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQ 1279
            +E  YC CN VSYGDMI CD   C  EWFH+GCV L   PKG WFC  C+  N +
Sbjct:   57 DEPTYCLCNQVSYGDMIGCDNEACAIEWFHFGCVGLSHKPKGKWFCPRCRGPNER 111

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Yeast
Match: YNG1 (Subunit of the NuA3 histone acetyltransferase complex; this complex acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3; shares significant sequence identity with the human candidate tumor suppressor p33-ING1 in C-terminal region [Source:SGD;Acc:S000005590])

HSP 1 Score: 88.1965 bits (217), Expect = 1.138e-20
Identity = 37/65 (56.92%), Postives = 44/65 (67.69%), Query Frame = 2

Query: 1091 DMLGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFC-RDCKTKNRQR 1282
            D+   + N+E  YCFC +VSYG M+ACD   CP EWFHYGCV L  APKG W+C +DCK    QR
Sbjct:  145 DVTEGNNNQEEVYCFCRNVSYGPMVACDNPACPFEWFHYGCVGLKQAPKGKWYCSKDCKEIANQR 209

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Yeast
Match: YNG2 (Subunit of NuA4, an essential histone acetyltransferase complex; positions Piccolo NuA4 for efficient acetylation of histone H4 or histone H2A; relocalizes to the cytosol in response to hypoxia; similar to human tumor suppressor ING1 and its isoforms ING4 and ING5 [Source:SGD;Acc:S000001132])

HSP 1 Score: 83.9593 bits (206), Expect = 1.139e-18
Identity = 32/56 (57.14%), Postives = 40/56 (71.43%), Query Frame = 2

Query: 1127 YCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKT---KNRQRR 1285
            YCFC  VS+G+M+ACDG  C  EWFHY CVNL   PKG+W+C +CK    KN+ +R
Sbjct:  224 YCFCQRVSFGEMVACDGPNCKYEWFHYDCVNLKEPPKGTWYCPECKIEMEKNKLKR 279

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Yeast
Match: PHO23 (Component of the Rpd3L histone deacetylase complex; involved in transcriptional regulation of PHO5; affects termination of snoRNAs and cryptic unstable transcripts (CUTs); C-terminus shares significant sequence identity with the human candidate tumor suppressor p33-ING1 and its isoform ING3 [Source:SGD;Acc:S000005041])

HSP 1 Score: 81.6481 bits (200), Expect = 1.097e-17
Identity = 27/48 (56.25%), Postives = 33/48 (68.75%), Query Frame = 2

Query: 1127 YCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTK 1270
            YC+CN V+YG+M+ CDG  C  EWFH  C+ L   PKG W+C DCK K
Sbjct:  282 YCYCNQVAYGEMVGCDGADCELEWFHLPCIGLETLPKGKWYCDDCKKK 329

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
Match: EDO40594 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6P9])

HSP 1 Score: 84.7297 bits (208), Expect = 1.214e-20
Identity = 36/61 (59.02%), Postives = 43/61 (70.49%), Query Frame = 2

Query: 1103 FDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG W+C  C T+ +Q+R
Sbjct:    6 YDPNEP-RYCLCNQVSYGEMVGCDNNDCPIEWFHYGCVGLTDAPKGKWYCPQCSTQIKQKR 65

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
Match: EDO43857 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXJ4])

HSP 1 Score: 72.4034 bits (176), Expect = 1.951e-14
Identity = 29/63 (46.03%), Postives = 37/63 (58.73%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            +  D NE   YC CN VS+G+MI CD   C  EWFH+ CV L   PKG W+C  C  + ++ R
Sbjct:  196 IPIDPNEPT-YCLCNQVSFGEMIGCDNEECQIEWFHFQCVGLSHKPKGKWYCPRCMQERKKER 257

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
Match: EDO37532 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFP0])

HSP 1 Score: 68.5514 bits (166), Expect = 1.301e-13
Identity = 25/48 (52.08%), Postives = 36/48 (75.00%), Query Frame = 2

Query: 1142 DVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            +VSYG+MI CD + CP EWFH+ CV LV  PKG W+C  C +++R+++
Sbjct:  134 NVSYGEMIGCDNMECPIEWFHFPCVGLVAKPKGKWYCPKC-SQDRKKK 180

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
Match: EDO35780 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKJ2])

HSP 1 Score: 53.9138 bits (128), Expect = 7.126e-10
Identity = 21/43 (48.84%), Postives = 24/43 (55.81%), Query Frame = 2

Query: 1127 YCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCR 1255
            YC C     G+MIACD   CP  WFH  C+ +  AP G W CR
Sbjct:    1 YCLCGQGESGEMIACDSPSCPIVWFHMDCIGMTTAPDGEWLCR 43

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
Match: EDO33191 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSY4])

HSP 1 Score: 52.373 bits (124), Expect = 2.526e-9
Identity = 20/48 (41.67%), Postives = 28/48 (58.33%), Query Frame = 2

Query: 1127 YCFCN--DVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCK 1264
            +C C   +    +MI CD   C  +WFH+ C+ L  APKG W+C+ CK
Sbjct:    1 FCVCQQPECEGDEMIGCDNPSCKYKWFHFTCIKLKRAPKGGWYCKFCK 48

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Medaka
Match: ing3 (inhibitor of growth family member 3 [Source:NCBI gene;Acc:101168096])

HSP 1 Score: 93.2041 bits (230), Expect = 2.296e-20
Identity = 37/62 (59.68%), Postives = 42/62 (67.74%), Query Frame = 2

Query: 1103 FDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
            +D NE  RYC CN VSYG+M+ CD   CP EWFHYGCV L  APKG W+C  C T   +RRG
Sbjct:  353 YDPNEP-RYCICNQVSYGEMVGCDNTDCPIEWFHYGCVGLTEAPKGKWYCPQC-TAAMKRRG 412

HSP 2 Score: 51.9878 bits (123), Expect = 3.234e-12
Identity = 32/94 (34.04%), Postives = 50/94 (53.19%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQVQE-----YEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIE 412
            N  + L+ R+ +FF    +N     ++  E     Y K L++ DE       K+ +  Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct:   34 NATDQLEQRVIDFFINAKKNKPEWREEQMEVIKKDYYKALEDADE-------KVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120

HSP 3 Score: 38.891 bits (89), Expect = 3.234e-12
Identity = 15/32 (46.88%), Postives = 24/32 (75.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLY ED++E IE LP + ++  T +R++DLQ+
Sbjct:    1 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Medaka
Match: ing5a (inhibitor of growth family member 5 [Source:NCBI gene;Acc:101171565])

HSP 1 Score: 81.2629 bits (199), Expect = 4.345e-17
Identity = 32/63 (50.79%), Postives = 42/63 (66.67%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            +  D NE   YC C+ VSYG+MI CD   CP EWFH+ CV+L   PKG WFC  C T++R+++
Sbjct:  181 MPVDPNEPT-YCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLATKPKGKWFCPRC-TQDRKKK 241

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Medaka
Match: ing2 (inhibitor of growth family member 2 [Source:NCBI gene;Acc:101160358])

HSP 1 Score: 77.7962 bits (190), Expect = 9.882e-16
Identity = 30/59 (50.85%), Postives = 34/59 (57.63%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKN 1273
               D NE   YC C  VSYG+MI CD   CP EWFH+ CV L   PKG W+C  C+  N
Sbjct:  208 FAIDPNEPT-YCLCEQVSYGEMIGCDNEQCPIEWFHFSCVGLTYKPKGKWYCPKCRGDN 265

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Medaka
Match: ing4 (inhibitor of growth family member 4 [Source:NCBI gene;Acc:105355951])

HSP 1 Score: 75.8702 bits (185), Expect = 2.958e-15
Identity = 29/63 (46.03%), Postives = 40/63 (63.49%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRR 1285
            +  D NE   YC C+ VSYG+MI CD   C  EWFH+ CV L   P+G W+C  C +++R+R+
Sbjct:  189 MPVDPNEPT-YCLCHQVSYGEMIGCDNTECSIEWFHFACVGLTTKPRGKWYCPRC-SQDRKRK 249

[Close]

BLAST of Inhibitor of growth protein vs. Ensembl Medaka
Match: ing1 (inhibitor of growth family member 1 [Source:NCBI gene;Acc:101155310])

HSP 1 Score: 76.2554 bits (186), Expect = 4.823e-15
Identity = 27/51 (52.94%), Postives = 33/51 (64.71%), Query Frame = 2

Query: 1127 YCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQ 1279
            YC C  VSYG+MI CD   CP EWFH+ CV L   PKG W+C  C+ +N +
Sbjct:  237 YCLCEQVSYGEMIGCDNDECPIEWFHFSCVGLHHKPKGKWYCPKCRGENEK 287

[Close]

BLAST of Inhibitor of growth protein vs. Planmine SMEST
Match: SMESG000056794.1 (SMESG000056794.1)

HSP 1 Score: 745.732 bits (1924), Expect = 0.000e+0
Identity = 380/381 (99.74%), Postives = 381/381 (100.00%), Query Frame = 2

Query:  146 NIMEPLDSRLNEFFQKCSQNTLSVSQQVQEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIELMVNQQMKSGVTDGIPRVERKRMKRGRLAFDSNISLQPNSESTRKIIRPKDTTESFSYKSEKIDGFGSISGQSDTLMTTAVANGSLSPASSFMGSLNTPHSIKRKFDWKQASSISTDKLVKSERKRQKIMSALSEDSGSNLGANDEFGLDEXXXXXXXXXXXXXXXXXXXEPDTNPRKSVPNDGMSDGGSSRTPGSLNFGMYSEPMISGSNTIQQISQDSQMNLDNDMLGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 1288
            NIMEPLDSRLNEFFQKCSQNTLSVSQQVQEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIELMVNQQMKSGVTDGIPRVERKRMKRGRLAFDSNISLQPNSESTRKIIRPKDTTESFSYKSEKIDGFGSISGQSDTLMTTAVANGSLSPASSFMGSLNTPHSIKRKFDWKQASSISTDKLVKSERKRQKIMSALSEDSGSNLGANDEFGLDESANSSSVINNP+NPSVSVSEPDTNPRKSVPNDGMSDGGSSRTPGSLNFGMYSEPMISGSNTIQQISQDSQMNLDNDMLGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG
Sbjct:   34 NIMEPLDSRLNEFFQKCSQNTLSVSQQVQEYEKILKEFDEVECKNADKIAITEQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIELMVNQQMKSGVTDGIPRVERKRMKRGRLAFDSNISLQPNSESTRKIIRPKDTTESFSYKSEKIDGFGSISGQSDTLMTTAVANGSLSPASSFMGSLNTPHSIKRKFDWKQASSISTDKLVKSERKRQKIMSALSEDSGSNLGANDEFGLDESANSSSVINNPINPSVSVSEPDTNPRKSVPNDGMSDGGSSRTPGSLNFGMYSEPMISGSNTIQQISQDSQMNLDNDMLGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTKNRQRRG 414

HSP 2 Score: 69.707 bits (169), Expect = 1.144e-12
Identity = 31/32 (96.88%), Postives = 32/32 (100.00%), Query Frame = 3

Query:   54 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQI 149
            MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQ+
Sbjct:    1 MLYFEDFMEDIEDLPYEFKENLTAIRQLDLQV 32

[Close]

BLAST of Inhibitor of growth protein vs. Planmine SMEST
Match: SMESG000007903.1 (SMESG000007903.1)

HSP 1 Score: 78.9518 bits (193), Expect = 2.602e-16
Identity = 32/62 (51.61%), Postives = 41/62 (66.13%), Query Frame = 2

Query: 1088 NDMLGFDTNE-ELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTK 1270
            N++L   T+  E  YC C+DVSYGDMI CD + CP EWFH+ CV +   PKG W+C  C+ K
Sbjct:  201 NEVLEMPTDPYEPVYCDCHDVSYGDMIGCDNIDCPIEWFHFACVGITDKPKGLWYCPRCRPK 262

[Close]

BLAST of Inhibitor of growth protein vs. Planmine SMEST
Match: SMESG000073543.1 (SMESG000073543.1)

HSP 1 Score: 73.9442 bits (180), Expect = 4.520e-15
Identity = 29/58 (50.00%), Postives = 39/58 (67.24%), Query Frame = 2

Query: 1097 LGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTK 1270
            +  D NE + YC C+ VS+G+M+ACD   C  EWFH+ CV+L   PKG WFC +C+ K
Sbjct:  148 MPVDPNEPV-YCLCHQVSFGEMVACDNKNCSIEWFHFSCVSLTSKPKGMWFCPNCRGK 204

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BLAST of Inhibitor of growth protein vs. Planmine SMEST
Match: SMESG000015211.1 (SMESG000015211.1)

HSP 1 Score: 75.485 bits (184), Expect = 5.751e-15
Identity = 29/48 (60.42%), Postives = 33/48 (68.75%), Query Frame = 2

Query: 1127 YCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKTK 1270
            YC CN  SYGDMIACD   C  EWFHY CV++  +PKG WFC  CK +
Sbjct:  257 YCICNKPSYGDMIACDSDKCKIEWFHYKCVDITTSPKGDWFCPVCKIE 304

[Close]

BLAST of Inhibitor of growth protein vs. Planmine SMEST
Match: SMESG000025474.1 (SMESG000025474.1)

HSP 1 Score: 73.559 bits (179), Expect = 1.666e-14
Identity = 28/56 (50.00%), Postives = 35/56 (62.50%), Query Frame = 2

Query: 1100 GFDTNEELRYCFCNDVSYGDMIACDGVGCPREWFHYGCVNLVVAPKGSWFCRDCKT 1267
            G   N+E  YC+C   +YG MIACD  GC  EWFH  CVN++  P G WFC +C+ 
Sbjct:  203 GKKNNKENCYCYCKKGAYGKMIACDNSGCKIEWFHNKCVNVIDVPNGEWFCPECRA 258

The following BLAST results are available for this feature:

BLAST of Inhibitor of growth protein vs. Ensembl Human
BLAST of Inhibitor of growth protein vs. Ensembl Celegans
BLAST of Inhibitor of growth protein vs. Ensembl Fly
BLAST of Inhibitor of growth protein vs. Ensembl Zebrafish
BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
BLAST of Inhibitor of growth protein vs. Ensembl Mouse
BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
BLAST of Inhibitor of growth protein vs. TrEMBL
BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
BLAST of Inhibitor of growth protein vs. Ensembl Sea Lamprey
BLAST of Inhibitor of growth protein vs. Ensembl Yeast
BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
BLAST of Inhibitor of growth protein vs. Ensembl Medaka
BLAST of Inhibitor of growth protein vs. Planmine SMEST

BLAST of Inhibitor of growth protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ING3	2.803e-20	48.84	inhibitor of growth family member 3 [Source:HGNC S...	[more]
ING3	2.884e-20	48.84	inhibitor of growth family member 3 [Source:HGNC S...	[more]
ING5	3.288e-17	49.21	inhibitor of growth family member 5 [Source:HGNC S...	[more]
ING1	1.959e-16	54.24	inhibitor of growth family member 1 [Source:HGNC S...	[more]
ING1	3.144e-16	54.24	inhibitor of growth family member 1 [Source:HGNC S...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ing-3	2.175e-15	46.30	Inhibitor of growth protein [Source:UniProtKB/TrE...	[more]
Y43H11AL.1	4.705e-11	41.18	pep chromosome:WBcel235:II:222704:223799:-1 gene:W...	[more]
Y43H11AL.1	4.705e-11	41.18	pep chromosome:WBcel235:II:222704:228035:-1 gene:W...	[more]
Y43H11AL.1	2.027e-10	32.99	pep chromosome:WBcel235:II:222704:230070:-1 gene:W...	[more]
Y43H11AL.1	2.626e-10	32.99	pep chromosome:WBcel235:II:222704:232029:-1 gene:W...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ing3	5.215e-19	58.06	gene:FBgn0030945 transcript:FBtr0074614	[more]
Ing5	1.536e-16	54.72	gene:FBgn0032516 transcript:FBtr0080525	[more]
Ing5	1.694e-16	54.72	gene:FBgn0032516 transcript:FBtr0080526	[more]
CG7379	6.333e-16	56.00	gene:FBgn0038546 transcript:FBtr0083529	[more]
MESR4	3.604e-12	52.08	gene:FBgn0034240 transcript:FBtr0340220	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ing3	5.862e-20	59.68	inhibitor of growth family, member 3 [Source:ZFIN;...	[more]
ing5a	6.737e-17	50.79	inhibitor of growth family, member 5a [Source:ZFIN...	[more]
ing5a	6.737e-17	50.79	inhibitor of growth family, member 5a [Source:ZFIN...	[more]
ing2	2.207e-15	52.63	inhibitor of growth family, member 2 [Source:ZFIN;...	[more]
ing5b	3.425e-15	57.78	inhibitor of growth family, member 5b [Source:ZFIN...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tmem192	1.571e-19	59.68	transmembrane protein 192 [Source:Xenbase;Acc:XB-G...	[more]
ccnf	1.097e-16	51.56	cyclin F [Source:Xenbase;Acc:XB-GENE-963729]	[more]
lman1l	2.348e-16	51.61	lectin, mannose-binding, 1 like [Source:Xenbase;Ac...	[more]
atp2b2	1.793e-15	50.82	ATPase, Ca++ transporting, plasma membrane 2 [Sour...	[more]
ING4	1.164e-13	48.08	inhibitor of growth family member 4 [Source:NCBI g...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ing3	9.456e-21	48.84	inhibitor of growth family, member 3 [Source:MGI S...	[more]
Ing3	1.014e-20	48.84	inhibitor of growth family, member 3 [Source:MGI S...	[more]
Ing5	2.193e-17	49.21	inhibitor of growth family, member 5 [Source:MGI S...	[more]
Ing5	2.675e-17	49.21	inhibitor of growth family, member 5 [Source:MGI S...	[more]
Ing2	3.749e-16	50.82	inhibitor of growth family, member 2 [Source:MGI S...	[more]

BLAST of Inhibitor of growth protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8VEK6\|ING3_MOUSE	7.093e-20	48.84	Inhibitor of growth protein 3 OS=Mus musculus OX=1...	[more]
sp\|Q498T3\|ING3_RAT	8.879e-20	48.84	Inhibitor of growth protein 3 OS=Rattus norvegicus...	[more]
sp\|Q5RBA1\|ING3_PONAB	1.359e-19	48.84	Inhibitor of growth protein 3 OS=Pongo abelii OX=9...	[more]
sp\|Q9NXR8\|ING3_HUMAN	1.385e-19	48.84	Inhibitor of growth protein 3 OS=Homo sapiens OX=9...	[more]
sp\|Q5ZK36\|ING3_CHICK	6.594e-19	59.68	Inhibitor of growth protein 3 OS=Gallus gallus OX=...	[more]

BLAST of Inhibitor of growth protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5N4AAI4	2.456e-33	28.35	Uncharacterized protein OS=Photinus pyralis OX=705...	[more]
A0A2P6K8Y4	2.521e-32	27.71	Inhibitor of growth protein OS=Nephila clavipes OX...	[more]
K1PV61	2.883e-31	26.41	Inhibitor of growth protein OS=Crassostrea gigas O...	[more]
A0A4Y2F1K6	1.728e-30	27.20	Inhibitor of growth protein OS=Araneus ventricosus...	[more]
A0A1J1HNQ8	3.543e-29	26.25	Inhibitor of growth protein OS=Clunio marinus OX=5...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ing3	6.425e-20	59.68	inhibitor of growth family member 3 [Source:NCBI g...	[more]
ing5a	1.047e-16	50.79	inhibitor of growth family member 5 [Source:NCBI g...	[more]
ing5b	1.511e-16	53.85	inhibitor of growth protein 5-like [Source:NCBI ge...	[more]
ing1	1.944e-15	50.82	inhibitor of growth protein 1-like [Source:NCBI ge...	[more]
ing2	2.596e-15	55.10	inhibitor of growth family member 2 [Source:NCBI g...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000000234.1	9.260e-20	46.59	pep scaffold:Pmarinus_7.0:GL482739:14:2848:1 gene:...	[more]
ENSPMAT00000008794.1	5.231e-17	56.36	pep scaffold:Pmarinus_7.0:GL476329:1735629:1740570...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
YNG1	1.138e-20	56.92	Subunit of the NuA3 histone acetyltransferase comp...	[more]
YNG2	1.139e-18	57.14	Subunit of NuA4, an essential histone acetyltransf...	[more]
PHO23	1.097e-17	56.25	Component of the Rpd3L histone deacetylase complex...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO40594	1.214e-20	59.02	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43857	1.951e-14	46.03	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37532	1.301e-13	52.08	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35780	7.126e-10	48.84	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33191	2.526e-9	41.67	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Inhibitor of growth protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ing3	2.296e-20	59.68	inhibitor of growth family member 3 [Source:NCBI g...	[more]
ing5a	4.345e-17	50.79	inhibitor of growth family member 5 [Source:NCBI g...	[more]
ing2	9.882e-16	50.85	inhibitor of growth family member 2 [Source:NCBI g...	[more]
ing4	2.958e-15	46.03	inhibitor of growth family member 4 [Source:NCBI g...	[more]
ing1	4.823e-15	52.94	inhibitor of growth family member 1 [Source:NCBI g...	[more]

BLAST of Inhibitor of growth protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000056794.1	1.144e-12	99.74	SMESG000056794.1	[more]
SMESG000007903.1	2.602e-16	51.61	SMESG000007903.1	[more]
SMESG000073543.1	4.520e-15	50.00	SMESG000073543.1	[more]
SMESG000015211.1	5.751e-15	60.42	SMESG000015211.1	[more]
SMESG000025474.1	1.666e-14	50.00	SMESG000025474.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30000147 ID=SMED30000147|Name=Inhibitor of growth protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1304bp
TATTTGTAAATATATCTATTTATACATTTTCAAATCATCATAAAATCCCT
AAAATGTTGTATTTCGAAGATTTTATGGAAGATATCGAGGATCTTCCTTA
TGAGTTTAAGGAAAATTTGACAGCTATTAGGCAACTTGATTTACAAATAT
TATGGAGCCTCTCGATTCACGCTTGAATGAGTTTTTTCAAAAATGTAGTC
AAAATACTCTATCAGTTTCGCAACAAGTACAAGAATATGAAAAAATATTA
AAAGAATTTGATGAAGTAGAATGCAAAAATGCAGATAAAATTGCAATAAC
TGAGCAGATGAAGGATACATTCAATAAAATGATAAAGAAATTAGACACTG
AATTAAATAAATTCAAATTAGAATTAGAAGCTGATAATCCTGGTAGTGCA
GAGACTATTGAATTAATGGTAAATCAACAAATGAAATCTGGTGTTACTGA
TGGAATTCCTCGAGTTGAAAGAAAACGAATGAAACGAGGTAGATTGGCAT
TTGATTCTAATATTAGTTTGCAACCAAATTCTGAAAGCACCAGAAAAATT
ATAAGGCCAAAAGACACGACTGAATCTTTCAGCTATAAATCTGAAAAAAT
AGATGGTTTTGGATCGATTTCCGGACAAAGTGATACTTTAATGACGACAG
CTGTGGCAAATGGGTCTTTATCTCCTGCATCATCGTTTATGGGTTCTTTG
AATACTCCTCATTCAATCAAACGAAAATTCGATTGGAAACAAGCATCATC
AATTTCCACAGATAAACTTGTGAAATCGGAAAGAAAACGGCAGAAAATAA
TGTCTGCTCTAAGTGAGGACTCGGGGAGCAATCTCGGTGCAAATGATGAA
TTTGGTTTGGATGAAAGTGCTAACAGCAGTTCAGTGATAAATAATCCCGT
CAATCCGTCTGTTTCTGTTTCGGAGCCAGACACAAATCCCCGGAAATCCG
TGCCCAATGATGGCATGTCAGACGGGGGATCGAGCAGAACTCCGGGCAGT
TTGAATTTCGGCATGTATAGTGAACCAATGATATCGGGTTCCAATACCAT
ACAGCAGATATCTCAGGACAGTCAAATGAATCTCGATAACGATATGCTTG
GGTTTGATACAAACGAGGAGCTGCGCTATTGTTTCTGCAATGACGTCAGT
TATGGCGATATGATAGCCTGTGATGGAGTCGGGTGTCCCCGGGAATGGTT
TCATTATGGCTGTGTCAATCTCGTTGTAGCTCCCAAGGGCAGCTGGTTTT
GTCGAGATTGCAAGACCAAAAACCGGCAACGAAGAGGCTAGTGAAATGTA
ATCA

protein sequence of SMED30000147-orf-1

>SMED30000147-orf-1 ID=SMED30000147-orf-1|Name=SMED30000147-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=380bp
MEPLDSRLNEFFQKCSQNTLSVSQQVQEYEKILKEFDEVECKNADKIAIT
EQMKDTFNKMIKKLDTELNKFKLELEADNPGSAETIELMVNQQMKSGVTD
GIPRVERKRMKRGRLAFDSNISLQPNSESTRKIIRPKDTTESFSYKSEKI
DGFGSISGQSDTLMTTAVANGSLSPASSFMGSLNTPHSIKRKFDWKQASS
ISTDKLVKSERKRQKIMSALSEDSGSNLGANDEFGLDESANSSSVINNPV
NPSVSVSEPDTNPRKSVPNDGMSDGGSSRTPGSLNFGMYSEPMISGSNTI
QQISQDSQMNLDNDMLGFDTNEELRYCFCNDVSYGDMIACDGVGCPREWF
HYGCVNLVVAPKGSWFCRDCKTKNRQRRG*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0006325	chromatin organization
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0016569	covalent chromatin modification
GO:0040008	regulation of growth
GO:0043065	positive regulation of apoptotic process
GO:0043967	histone H4 acetylation
GO:0043968	histone H2A acetylation

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell
PLANA:0000142	posterior region of the whole animal

Vocabulary: **INTERPRO**
Term	Definition
IPR028651	ING_fam
IPR024610	ING_N_histone-binding
IPR001965	Znf_PHD
IPR013083	Znf_RING/FYVE/PHD
IPR019786	Zinc_finger_PHD-type_CS
IPR019787	Znf_PHD-finger
IPR011011	Znf_FYVE_PHD

Vocabulary: **molecular function**
Term	Definition
GO:0008270	zinc ion binding
GO:0005515	protein binding
GO:0046872	metal ion binding

Vocabulary: **cellular component**
Term	Definition
GO:0000812	Swr1 complex
GO:0005634	nucleus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001965	Zinc finger, PHD-type	SMART	SM00249	PHD_3	coord: 326..371 e-value: 6.5E-10 score: 48.9
IPR013083	Zinc finger, RING/FYVE/PHD-type	GENE3D	G3DSA:3.30.40.10		coord: 322..379 e-value: 1.3E-23 score: 84.7
IPR024610	Inhibitor of growth protein, N-terminal histone-binding	PFAM	PF12998	ING	coord: 4..71 e-value: 3.2E-5 score: 24.4
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 239..278
None	No IPR available	CDD	cd15505	PHD_ING	coord: 326..370 e-value: 3.99741E-25 score: 94.2874
None	No IPR available	CDD	cd16858	ING_ING3_Yng2p	coord: 1..65 e-value: 4.2271E-9 score: 51.0492
IPR028651	ING family	PANTHER	PTHR10333	INHIBITOR OF GROWTH PROTEIN	coord: 4..378
IPR019786	Zinc finger, PHD-type, conserved site	PROSITE	PS01359	ZF_PHD_1	coord: 327..370
IPR019787	Zinc finger, PHD-finger	PROSITE	PS50016	ZF_PHD_2	coord: 324..373 score: 9.027
IPR011011	Zinc finger, FYVE/PHD-type	SUPERFAMILY	SSF57903	FYVE/PHD zinc finger	coord: 316..373