EGF-like domain-containing protein

Overview
NameEGF-like domain-containing protein
Smed IDSMED30000129
Length (bp)6167
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of EGF-like domain-containing protein (SMED30000129) t-SNE clustered cells

Violin plots show distribution of expression levels for EGF-like domain-containing protein (SMED30000129) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of EGF-like domain-containing protein (SMED30000129) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for EGF-like domain-containing protein (SMED30000129) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30000129

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30000129SMESG000009899.1 SmedASXL_017586SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30000129SMESG000009899.1 dd_Smed_v4_10627_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30000129SMESG000009899.1 dd_Smed_v4_10627_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30000129SMESG000009899.1 dd_Smed_v4_10627_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30000129SMESG000009899.1 dd_Smed_v4_15631_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30000129SMESG000009899.1 dd_Smed_v4_15631_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30000129SMESG000009899.1 Contig40771newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30000129SMESG000009899.1 Contig40771uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30000129SMESG000009899.1 dd_Smed_v6_15631_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30000129SMESG000009899.1 dd_Smed_v6_10627_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
neuronSMED30000129SMESG000009899.1 dd_Smed_v6_10627_0_1dd_Smed_v6PMID:30399335
Ross et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
GABAergic neuronSMED30000129SMESG000009899.1 dd_Smed_v6_10627_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
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BLAST of EGF-like domain-containing protein vs. TrEMBL
Match: A0A267GA83 (EGF-like domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018624g3 PE=4 SV=1)

HSP 1 Score: 534.258 bits (1375), Expect = 6.767e-154
Identity = 510/1885 (27.06%), Postives = 873/1885 (46.31%), Query Frame = 2 
Query:  509 FTGPTCALFSNKLPHFEKSSYHLVFNESKKDTTPVIKVTAIDEDKCVRGNCECGEIIYSIL-EENAKELFEINSSSGEIKVIQGAVIPETKYSFSVKVTNRNPFDDRYDTATIFVNGDSS---NEILERHRRATAPT-KPAFELIQTFPIQNLTSINIGQRLSMQLSVAFPVGTTTLSVELFAPESQSYPVMMICDVNVISVGSLL---TTNSYNPPLQEGINGTVWPYTHIVYNFTNVINAQSSVTSLADIQIVITFDVVMLYSPNTTDGATYYVSGGSEYLNGTEIWVGQLGYIAN-----LXXXXXXXXXXXXGDTLVYPGRTAAFVLTIQAPDSYLYLN--LGIYSPLNNSVALSLC-VVNRYYVGAAYSCLPTNY--NQPTLKQVTINNQIYYTSAL-MNLGILGNRYYMEPTHTDMNEKTINISITARISPTLWLGTYQYIGLSISNTLTTIYT--KTYQVL---VSPAPQLTAYTSPISYSLGYHKNITSVSIGSPGR-----ININISIPTGTELDYTIIARSPENTS----EICGVIFFKAGLNIPCVDQ----ITFGTTYVYTPD-------NFATTSITSIGGIRHVKISNNTDDDILQLVLVFRPINDSRNSVNGIT---NIGVKV---NWTGSTGTENFLPVTLNAPDVSSANSTTLPTFTFQLXXXXXXXXXXXXYKLFFAMRLYPGTIYTPTSLEFYMPF-NGTIRVGMCKASITYVGKNVLCFNPTFITKSFIFSSKINDTSNYDKLLIPTGVLCTSGSSSAAPS--INDEIQISINILILPHAMNTV--GATANLNGGMMISSTQIWVGNQPLTFITIPAIXXXXXXXXXXXFAQRVDSTSSNVWINDMVIIQYIIKVAPAVVTRMTLSISTDATVATNNFGVCQVKIINQGLSIPCVNGT---------LTTTPATAFSKFYVSGNFAFTDILNTGTVALVANPTFDENSLLVEVIVKLGP--TLPPSFNVIASLTSNGAT--ASANVPLTFTSAFSRFNGTVASTEPVFNMFLYPLFNDT-NAVINNIAYSEAMRSVVSVEMKPNVLQSLKIVFASTPNI--VNQMDVISVNILSVGRNIPCLQKGMIPFSIQQRSNSLSKDLASIDMGTICHRPYLDNTTVEDNKIYIESVFRIW-KFPATSPLTLQINVLGLLNNDQVYVTR--IVFNTSTTPFVTDFSLTGESFNANATISSAS---VAVGGNFTVKVMVTIPPYTQFKSGTITVGNQNPVGSDSFYFINGNANFSGTSGQNIGINKDEPMPFTLKSTFNTSQLDNIVADLGVVQNTATTYRMNQVNYSAXXXXXXXXXXXXXQLTDNSMASNGQIINFIVGVSFGSKTLNFSLQITVLRINNETMDFXXXXXXXXXXXXXXXXXPIIASAQAIML-NTSTLECRNFSIFVAAPPFIQLSSVVNTSYTSPGYPTVAKNIPIAGFSFNVPYFFYKENITIIFTMSVIAGLN--LTKGRAQSSITIPVVYSCQTLNWPLNPMGNKYFNKVETLVFTVKGXXXXXXXXXXXXXXXXKDSSVIQDCAISAYMSPYPGFEATKIRSNSGSYWVPHIRSGQYNKLRYIDIKFG--KLXXXXXXXXXXXXGNKPQTLGIHGTMDGRAFSFYQNINIS-YNPDNTAAVTLNNPPFTYRGIRVSIVVANQDDINTGMNLDLFGCLPPNVTDTFTFDPCATKSYLVPTNPLPEFYYRGYLY---TNQQLFVCDEIVSLSFGLETYPRCFRTNTATFTTWEDLGNQVGKVIGFDSVNMIIYAIA-------SDIKSYIMSEDNGLTWVGINGGGWQ-IMKNTASLQSPI----VIPWTNDTTFDYLTTGNNCTKYTVA-TFNFCYDGIYNGTSRIFSWNNCCNF 5866
            F G  C    N LP F+   Y     E       V  V+A D D   + NC+C ++IY++   +N +  F ++ ++G + V     +PE  +   ++ +N  PF       + FV  + +     +  R RRA  P     F+  QTFP  N+T + +G++L+ Q+ V FP+G T++++E+F+P++++  V+MICDV +ISVGS L    T   +    EG N   WPY  +   F  V ++ S  T  +D  + + ++ V LY+   ++   Y+VS G+EY N + IW+GQ  ++AN     ++T    P+I+ITGD+ +YPG  ++F L    P  YLY N  L ++ PLN++  LS+C +      G  + C+P +    + TL +   +   YY S L     +  N+ Y +P  T  ++  ++ +   + + +  +G   Y+G S+    TT+ +  KT QV    ++PA Q +    PI        ++T +  G  GR       + +    G   DY I A  P N S    +IC +    AG NIPC+ Q    I      +Y+ D       ++A  S+  +     V  S +   + + + +V   +N+   +V+G +    +GV      W G     NF     N  ++SS  + +LP  +      D   ++     +     L  G  Y P   EF  PF N +  + +C+A + +VGK + C + + +  +   +SK N+++ YDK +   G     G S++  S  IND I +  ++ +L H  +    G++ +L+ G   S+ QIW+G  P   +T P IP    ++    +    D T+   +  D      +IK     V+  TL +     +A +   VC    +  G +I CVN T         L  +    F     + N  +  I N G   LV +   D N+L + V  +  P  +   + +++A +  +G++    A V +T  S  +R       T P F+M + PL     N+  +  A  +  R+ ++V  KPN +Q L+I F S  +    N +D++   ++S G+N+PC        +  +R+ SL+ D  ++++G +C+ P    ++  DN+I I+   R+W   PA     + ++ +  +++ Q+ V +  I  N S TP    FSLTG S   NA+        V VG    VK+++ +P   +F S    +  +N   + S +      N + + G  +G+  +EP      S+  T QLD+    +  VQN+  +   N    S     +  TVT  ++L D+  A+N  +    +G+    + +     I V+R N E  +   S N+ +      S   I+     +   N S+ E +N  +F+  PP+I+L ++ N  Y S G   V +      F+FN   F  +   T+ F ++V    N  L   R  ++ T    +  +  +   N    +++ K  ++ F V+G         CN D  + D+S I  C IS++M+PY GFEA  +R      W PH+R G Y   RY+++ FG  K  +   +    +  NKP  L ++ TMDGRA++ ++ I+IS Y   + A  ++  P    RG+RV +   +  D    +  DLFGC      D+  FDPC+ + Y            R YLY   T+  ++ CD + + +  L    +C+R+ +A    W  LG  VG ++ + + +  +Y  A       +D +SY+ SEDNG+TW+  N   ++  +   +S  +P+    V+ WT    F    +G NCT Y     +  CYDGIY+ TS++ SWN+CC+ 
Sbjct:   47 FKGSRCDQLDNALPTFDTERYSASLPEGAAVGYRVTTVSAKDSDAATKPNCQCAKVIYTLEPSDNPRGFFAVDPNTGAVTVAASG-LPEGLHRIKIRASNPGPF-----ATSGFVVTEVAIDVEAVKSRQRRAIPPAGNVTFKYAQTFPTNNVTHLRMGEKLAFQVDVLFPLGDTSMNMEIFSPDNETAAVIMICDVKIISVGSRLNLNVTEVMSKATYEGKNNGSWPYVRVALPFGTVTHS-SGATVESDYTVSVAYEAVFLYNNIVSNNTEYWVSAGAEYNNESVIWIGQTSFLANTDKTDVATAKETPSINITGDSEIYPGTVSSFNLDFTVP--YLYSNFTLDVFGPLNDTEILSVCGIYTTASSGEGFGCMPRSSWPYEFTLSKQKASATNYYQSTLSFTSTLFTNKAYYKPGAT-TDDHRVSFAFAVKPNESAAVGNPTYVGASVDIGGTTVLSAYKTLQVANASLAPAAQNSTTVDPI-------ISLTRIGPGVLGRDQSTMFELALDTVPGI-FDYEIQALMPSNNSLGRLKICSMNVTYAGRNIPCLSQRMTSIAARYQILYSNDSVPSDQYDYAVISLPKLYNTGSVTASQDPLANRVTVRMV-ATVNNHTLNVDGESAYVTMGVSYADKQWVG-INQINF----TNVVNISSLPNESLPIVSLSYVLGDSYFNLYETAVIEAVTELRRGVTYAPMDFEFIAPFMNDSAVMTVCQAEVIFVGKYIGCSDKSSLINNIRLTSK-NNSTRYDKAVFSLGTTSNVGPSTSIDSSTINDRIVLRFHVKMLDHVAHASGNGSSYSLSFGFQFSTDQIWIGQLP-AVLTKPEIPLPTLAADKTPYVT-FDVTNLTAYPLDAQSAGLLIKFPSGSVSSYTLKL-----IAPSFGSVCAATFVFTGGNISCVNETSVEESVQRNLYNSSDKEFLALSSTYNLGY--IHNAGEFTLVKDTNTDANTLKLRVSFRTAPDASAGATGDLVAQVFYSGSSTPVEAKVGVTIASG-ARPVTLTNETAPTFSMSIVPLIEGMPNS--SQFAPGQGFRARLTVTTKPNSVQRLEIRFVSPVDTTSTNVVDLLDAGVVSAGKNLPCTIPWADASTATKRNGSLAYDTVAVNLGVVCNYP--AGSSEADNQIAIDLFGRVWTSSPAMPDGDILLSTVAFISDQQINVNQINITVNQSATP--PQFSLTGNSTAINASFEHTDDIYVKVGEYVEVKMLLQVP---EFFSSLFKLDIRNADTNLSAWATINVVNITQSGGNMMGL-ANEPYILNRTSSLGTFQLDSAELLVYTVQNSGLSSLKNSRFPS--NATNNFTVTYSIKLADHPNANNDSVFQMSLGLHLLDRIVVGLRDIKVMRDNTEWPNGTVSVNISSLPASIYSAGEIVTLYVNVSCSNWSSAELQNAVLFLHTPPYIKLVNMSNIQYASGGISAVERPDGGMKFAFNNTIFLAE---TVQFEINVAMKENFILPGNRETANATSVYEFVYKMFDRAGNLNSARWYRKAGSVFFQVRG--APAPPDGCNLDFGMNDTSKISSCQISSFMAPYAGFEAHNVRPALAG-WKPHVRGGDYKNFRYVNVVFGYLKRISRIIVYADGASANKPTCLNLYKTMDGRAYTLHKTIDISGYYVGHVANFSV-QPRLVGRGVRVGVCDTSVQDAEVIVRFDLFGCNYSAELDSNAFDPCSRQPY------DNGHCGRSYLYLNDTSDTIYYCDHVPTSTEELTGISKCYRSTSAQNRKWTYLGPAVGSIVAYHADSNRLYGYAQGCYGNTTDDRSYLFSEDNGITWIPTNPESYKGTVAKASSSSTPLLYQKVVHWTVSAEFQSGVSGPNCTAYDAGNNWKICYDGIYHSTSKVVSWNSCCSL 1871
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BLAST of EGF-like domain-containing protein vs. TrEMBL
Match: A0A267F069 (EGF-like domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018624g2 PE=4 SV=1)

HSP 1 Score: 530.02 bits (1364), Expect = 2.091e-152
Identity = 509/1885 (27.00%), Postives = 874/1885 (46.37%), Query Frame = 2 
Query:  509 FTGPTCALFSNKLPHFEKSSYHLVFNESKKDTTPVIKVTAIDEDKCVRGNCECGEIIYSIL-EENAKELFEINSSSGEIKVIQGAVIPETKYSFSVKVTNRNPFDDRYDTATIFVNGDSS---NEILERHRRATAPT-KPAFELIQTFPIQNLTSINIGQRLSMQLSVAFPVGTTTLSVELFAPESQSYPVMMICDVNVISVGSLL---TTNSYNPPLQEGINGTVWPYTHIVYNFTNVINAQSSVTSLADIQIVITFDVVMLYSPNTTDGATYYVSGGSEYLNGTEIWVGQLGYIAN-----LXXXXXXXXXXXXGDTLVYPGRTAAFVLTIQAPDSYLYLN--LGIYSPLNNSVALSLC-VVNRYYVGAAYSCLPTNY--NQPTLKQVTINNQIYYTSAL-MNLGILGNRYYMEPTHTDMNEKTINISITARISPTLWLGTYQYIGLSISNTLTTIYT--KTYQVL---VSPAPQLTAYTSPISYSLGYHKNITSVSIGSPGR-----ININISIPTGTELDYTIIARSPENTS----EICGVIFFKAGLNIPCVDQ----ITFGTTYVYTPD-------NFATTSITSIGGIRHVKISNNTDDDILQLVLVFRPINDSRNSVNGIT---NIGVKV---NWTGSTGTENFLPVTLNAPDVSSANSTTLPTFTFQLXXXXXXXXXXXXYKLFFAMRLYPGTIYTPTSLEFYMPF-NGTIRVGMCKASITYVGKNVLCFNPTFITKSFIFSSKINDTSNYDKLLIPTGVLCTSGSSSAAPS--INDEIQISINILILPHAMNTV--GATANLNGGMMISSTQIWVGNQPLTFITIPAIXXXXXXXXXXXFAQRVDSTSSNVWINDMVIIQYIIKVAPAVVTRMTLSISTDATVATNNFGVCQVKIINQGLSIPCVNGT---------LTTTPATAFSKFYVSGNFAFTDILNTGTVALVANPTFDENSLLVEVIVKLGP--TLPPSFNVIASLTSNGAT--ASANVPLTFTSAFSRFNGTVASTEPVFNMFLYPLFNDT-NAVINNIAYSEAMRSVVSVEMKPNVLQSLKIVFASTPNI--VNQMDVISVNILSVGRNIPCLQKGMIPFSIQQRSNSLSKDLASIDMGTICHRPYLDNTTVEDNKIYIESVFRIW-KFPATSPLTLQINVLGLLNNDQVYVTR--IVFNTSTTPFVTDFSLTGESFNANATISSAS---VAVGGNFTVKVMVTIPPYTQFKSGTITVGNQNPVGSDSFYFINGNANFSGTSGQNIGINKDEPMPFTLKSTFNTSQLDNIVADLGVVQNTATTYRMNQVNYSAXXXXXXXXXXXXXQLTDNSMASNGQIINFIVGVSFGSKTLNFSLQITVLRINNETMDFXXXXXXXXXXXXXXXXXPIIASAQAIML-NTSTLECRNFSIFVAAPPFIQLSSVVNTSYTSPGYPTVAKNIPIAGFSFNVPYFFYKENITIIFTMSVIAGLN--LTKGRAQSSITIPVVYSCQTLNWPLNPMGNKYFNKVETLVFTVKGXXXXXXXXXXXXXXXXKDSSVIQDCAISAYMSPYPGFEATKIRSNSGSYWVPHIRSGQYNKLRYIDIKFG--KLXXXXXXXXXXXXGNKPQTLGIHGTMDGRAFSFYQNINIS-YNPDNTAAVTLNNPPFTYRGIRVSIVVANQDDINTGMNLDLFGCLPPNVTDTFTFDPCATKSYLVPTNPLPEFYYRGYLY---TNQQLFVCDEIVSLSFGLETYPRCFRTNTATFTTWEDLGNQVGKVIGFDSVNMIIYAIA-------SDIKSYIMSEDNGLTWVGINGGGWQ-IMKNTASLQSPI----VIPWTNDTTFDYLTTGNNCTKYTVA-TFNFCYDGIYNGTSRIFSWNNCCNF 5866
            F G  C    N LP F+   Y     E       V  V+A D D   + NC+C ++IY++   +N +  F ++ ++G + V     +PE  +   ++ +N  PF       + FV  + +     +  R RRA  P     F+  QTFP  N+T + +G++L+ Q+ V FP+G T++++E+F+P++++  V+MICDV +ISVGS L    T   +    EG N   WPY  +   F  V ++ S  T  +D  + + ++ V LY+   ++   Y+VS G+EY N + IW+GQ  ++AN     ++T    P+I+ITGD+ +YPG  ++F L    P  YLY N  L ++ PLN++  LS+C +      G  + C+P +    + TL +   +   YY S L     +  N+ Y +P  T  ++  ++ +   + + +  +G   Y+G S+    TT+ +  KT QV    ++PA Q +    PI        ++T +  G  GR       + +    G   DY I A  P N S    +IC +    AG NIPC+ Q    I      +Y+ D       ++A  S+  +     V  S +   + + + +V   +N+   +V+G +    +GV      W G     NF     N  ++SS  + +LP  +      D   ++     +     L  G  Y P   EF  P+ N +  + +C+A + +VGK + C + + +  +   +SK N+++ YDK +   G     G S++  S  IND I +  ++ +L H ++    G++ +L+ G   S+ QIW+G  P   +T P IP    ++    +    D T+   +  D      +IK     V+  TL +     +A +   VC    +  G +I CVN T         L  +    F     + N  +  I N G   LV +   D N+L + V  +  P  +   + +++A +  +G++    A V +T  S  +R       T P F+M + PL     N+  +  A  +  R+ ++V  KPN +Q L+I F S  +    N +D++   ++S G+N+PC        +  +R+ SL+ D  ++++G +C+ P    ++  DN+I I+   R+W   PA     + ++ +  +++ Q+ V +  I  N S TP    FSLTG S   NA+    +   V VG    VK+++ +    +F S    +  +N   + S +      N + + G  +G+  +EP      S+  T QLD+    +  VQN+  +   N    S     +  TVT  ++L D+  A+N  +    +G+    + +     I V+R N E  +   S N+ +      S   I+     +   N S+ E +N  +F+  PP+I+L ++ N  Y S G   V +      F+FN   F  +   T+ F ++V    N  L   R  ++ T    +  +  +   N    +++ K  ++ F V+G         CN D  + D+S I  C IS++M+PY GFEA  +R      W PH+R G Y   RY+++ FG  K  +   +    +  NKP  L ++ TMDGRA++ ++ I+IS Y   + A  ++  P    RGIRV +   +  D    +  DLFGC      D+  FDPC+ + Y            R YLY   T+  ++ CD + + +  L    +C+R+ +A    W  LG  VG ++ + + +  +Y  A       +D +SY+ SEDNG+TW+  N   ++  +   +S  +P+    V+ WT    F    +G NCT Y     +  CYDGIY+ TS++ SWN+CC+ 
Sbjct:   47 FKGSRCDQLDNALPTFDTERYSASLPEGAAVGYRVTTVSAKDSDAATKPNCQCAKVIYTLEPSDNPRGFFAVDPNTGAVTVAASG-LPEGLHRIKIRASNPGPF-----ATSGFVVTEVAIDVEAVKSRQRRAIPPAGNVTFKYAQTFPTNNVTHLRMGEKLAFQVDVLFPLGDTSMNMEIFSPDNETAAVIMICDVKIISVGSRLNLNVTEVMSKATYEGKNNGSWPYVRVALPFGTVTHS-SGATVESDYTVSVAYEAVFLYNNIVSNNTEYWVSAGAEYNNESVIWIGQTSFLANTDKTDVATAKETPSINITGDSEIYPGTVSSFNLDFTVP--YLYSNFTLDVFGPLNDTEILSVCGIYTTASSGEGFGCMPRSSWPYEFTLSKQKASATNYYQSTLSFTSTLFTNKAYYKPGAT-TDDHRVSFAFAVKPNESAAVGNPTYVGASVDIGGTTVLSAYKTLQVANASLAPAAQNSTTVDPI-------ISLTRIGPGVLGRDQSTMFELALDTVPGI-FDYEIQALMPSNNSLGRLKICSMNVTYAGRNIPCLSQRMTSIAARYQILYSNDSVPSDQYDYAVISLPKLYNTGSVTTSQDPLANRVTVRMV-ATVNNHTLNVDGESAYVTMGVSYADKQWVG-INQINF----TNVVNISSLPNESLPIVSLSYVLGDSYFNLYETAVIEAVTELRRGVTYAPMDFEFIAPYMNDSAVMTVCRAEVIFVGKYIGCSDKSSLINNIRLTSK-NNSTRYDKAVFSLGTTSNVGPSTSIDSSTINDRIVLRFHVKMLDHVVHGSGNGSSYSLSFGFQFSTDQIWIGQLP-AVLTKPEIPLPTLAADKTPYVT-FDVTNLTAYPLDAQSAGLLIKFPSGSVSSYTLKL-----IAPSFGSVCAATFVFTGGNISCVNETSVEESVQRNLYNSSDKEFLALSSTYNLGY--IHNAGEFTLVKDTNTDANTLKLRVSFRTAPDASAGATGDLVAQVFYSGSSTPVEAKVGVTIASG-ARPVTLTNETAPTFSMSIVPLIEGMPNS--SQFAPGQGFRARLTVTTKPNSVQRLEIRFVSPVDTTSTNVVDLLDAGVVSAGKNLPCTIPWADASTATKRNGSLAYDTVAVNLGVVCNYP--AGSSEADNQIAIDLFGRVWTSSPAMPDGNILLSTVAFISDQQINVNQINITVNQSATP--PQFSLTGNSTAINASFEHTNDIYVKVGEYAEVKMLLQV---QEFFSSLFKLDIRNADTNLSAWATINVVNITQSGGNMMGL-ANEPYILNRTSSLGTFQLDSAELLVYTVQNSGLSSLKNSRFPS--NATNNFTVTYSIKLADHPNANNDSVFQMSLGLHLLDRIVVGLRDIKVMRDNTEWPNGTVSVNISSLPASIYSAGEIVTLYVNVSCSNWSSAELQNAVLFLHTPPYIKLVNMSNIQYASGGISAVERPDGGMKFAFNNTIFLAE---TVQFEINVAMKENFILPGNRETANATSVYEFVYKMFDRAGNLNSARWYRKAGSVFFQVRG--APAPPDGCNLDFGMNDTSKISSCQISSFMAPYAGFEAHNVRPALAG-WKPHVRGGDYKNFRYVNVVFGYLKRISRIIVYADGASANKPTCLNLYKTMDGRAYTLHKTIDISGYYVGHVANFSV-QPRLVGRGIRVGVCDTSVQDAEVIVRFDLFGCNYSAELDSNAFDPCSRQPY------DNGHCGRSYLYLNDTSDTIYYCDHVPTSTEELTGISKCYRSTSAQNRKWTYLGPAVGSIVAYHADSNRLYGYAQGCHGNTTDDRSYLFSEDNGITWIPTNPESYKGTVAKASSSSTPLLYQKVVHWTVSAEFQSGVSGPNCTAYDAGNNWKICYDGIYHSTSKVVSWNSCCSL 1871
[Close]
BLAST of EGF-like domain-containing protein vs. TrEMBL
Match: A0A267GYV5 (EGF-like domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018624g1 PE=4 SV=1)

HSP 1 Score: 525.783 bits (1353), Expect = 6.291e-151
Identity = 507/1885 (26.90%), Postives = 870/1885 (46.15%), Query Frame = 2 
Query:  509 FTGPTCALFSNKLPHFEKSSYHLVFNESKKDTTPVIKVTAIDEDKCVRGNCECGEIIYSIL-EENAKELFEINSSSGEIKVIQGAVIPETKYSFSVKVTNRNPFDDRYDTATIFVNGDSS---NEILERHRRATAPT-KPAFELIQTFPIQNLTSINIGQRLSMQLSVAFPVGTTTLSVELFAPESQSYPVMMICDVNVISVGSLL---TTNSYNPPLQEGINGTVWPYTHIVYNFTNVINAQSSVTSLADIQIVITFDVVMLYSPNTTDGATYYVSGGSEYLNGTEIWVGQLGYIAN-----LXXXXXXXXXXXXGDTLVYPGRTAAFVLTIQAPDSYLYLN--LGIYSPLNNSVALSLC-VVNRYYVGAAYSCLPTNY--NQPTLKQVTINNQIYYTSAL-MNLGILGNRYYMEPTHTDMNEKTINISITARISPTLWLGTYQYIGLSISNTLTTIYT--KTYQVL---VSPAPQLTAYTSPISYSLGYHKNITSVSIGSPGR-----ININISIPTGTELDYTIIARSPENTS----EICGVIFFKAGLNIPCVDQ----ITFGTTYVYTPD-------NFATTSITSIGGIRHVKISNNTDDDILQLVLVFRPINDSRNSVNGIT---NIGVKV---NWTGSTGTENFLPVTLNAPDVSSANSTTLPTFTFQLXXXXXXXXXXXXYKLFFAMRLYPGTIYTPTSLEFYMPF-NGTIRVGMCKASITYVGKNVLCFNPTFITKSFIFSSKINDTSNYDKLLIPTGVLCTSGSSSAAPS--INDEIQISINILILPHAMNTV--GATANLNGGMMISSTQIWVGNQPLTFITIPAIXXXXXXXXXXXFAQRVDSTSSNVWINDMVIIQYIIKVAPAVVTRMTLSISTDATVATNNFGVCQVKIINQGLSIPCVNGT---------LTTTPATAFSKFYVSGNFAFTDILNTGTVALVANPTFDENSLLVEVIVKLGP--TLPPSFNVIASLTSNGAT--ASANVPLTFTSAFSRFNGTVASTEPVFNMFLYPLFNDT-NAVINNIAYSEAMRSVVSVEMKPNVLQSLKIVFASTPNI--VNQMDVISVNILSVGRNIPCLQKGMIPFSIQQRSNSLSKDLASIDMGTICHRPYLDNTTVEDNKIYIESVFRIW-KFPATSPLTLQINVLGLLNNDQVYVTR--IVFNTSTTPFVTDFSLTGESFNANATISSAS---VAVGGNFTVKVMVTIPPYTQFKSGTITVGNQNPVGSDSFYFINGNANFSGTSGQNIGINKDEPMPFTLKSTFNTSQLDNIVADLGVVQNTATTYRMNQVNYSAXXXXXXXXXXXXXQLTDNSMASNGQIINFIVGVSFGSKTLNFSLQITVLRINNETMDFXXXXXXXXXXXXXXXXXPIIASAQAIML-NTSTLECRNFSIFVAAPPFIQLSSVVNTSYTSPGYPTVAKNIPIAGFSFNVPYFFYKENITIIFTMSVIAGLN--LTKGRAQSSITIPVVYSCQTLNWPLNPMGNKYFNKVETLVFTVKGXXXXXXXXXXXXXXXXKDSSVIQDCAISAYMSPYPGFEATKIRSNSGSYWVPHIRSGQYNKLRYIDIKFG--KLXXXXXXXXXXXXGNKPQTLGIHGTMDGRAFSFYQNINIS-YNPDNTAAVTLNNPPFTYRGIRVSIVVANQDDINTGMNLDLFGCLPPNVTDTFTFDPCATKSYLVPTNPLPEFYYRGYLY---TNQQLFVCDEIVSLSFGLETYPRCFRTNTATFTTWEDLGNQVGKVIGFDSVNMIIYAIA-------SDIKSYIMSEDNGLTWVGINGGGWQ-IMKNTASLQSPI----VIPWTNDTTFDYLTTGNNCTKYTVA-TFNFCYDGIYNGTSRIFSWNNCCNF 5866
            F G  C    N LP F+   Y     E       V  V+A D D   + NC+C ++IY++   +N +  F ++ ++G + V     +PE  +   ++ +N  PF       + FV  + +     +  R RRA  P     F+  QTFP  N+T + +G++L+ Q+ V FP+G T++++E+F+P++++  V+MICDV +ISVGS L    T   +    EG N   WPY  +   F  V ++ S  T  +D  + + ++ V LY+   ++   Y+VS G+EY N + IW+GQ  ++AN     ++T    P+I+ITGD+ +YPG  ++F L    P  YLY N  L ++ PLN++  LS+C +      G  + C+P +    + TL +   +   YY S L     +  N+ Y +P  T  ++  ++ +   + + +  +G   Y+G S+    TT+ +  KT QV    ++PA Q +    PI        ++T +  G  GR       + +    G   DY I A  P N S    +IC +    AG NIPC+ Q    I      +Y+ D       ++A  S+  +     V  S +   + + + +V   +N+   +V+G +    +GV      W G     NF     N  ++SS  + +LP  +      D   ++     +     L  G  Y P   EF  P+ N +  + +C+A + +VGK + C + + +  +   +SK N+++ YDK +   G     G S++  S  IND I +  ++ +L H  +    G++ +L+ G   S+ QIW+G  P   +T P IP    ++    +    D T+   +  D      +IK     V+  TL +     +A +   VC    +  G +I CVN T         L  +    F     + N  +  I N G   LV +   D N+L + V  +         + +++A +  +G++    A V +T  S  +R       T P F+M + PL     N+  +  A  +  R+ ++V  KPN +Q L+I F S  +    N +D++   ++S G+N+PC        +  +R+ SL+ D  ++++G +C+ P    ++  DN+I I+   R+W   PA     + ++ +  +++ Q+ V +  I  N S TP    FSLTG S   NA+        V VG    VK+++ +P   +F S    +  +N   + S +      N + + G  +G+  +EP      S+  T QLD+    +  VQN+  +   N    S     +  TVT  ++L D+  A+N  +    +G+    + +     I V+R N E  +   S N+ +      S   I+     +   N S+ E +N  +F+  PP+I+L ++ N  Y S     V +      F+FN   F  +   T+ F ++V    N  L   R  ++ T    +  +  +   N    +++ K  ++ F V+G         CN D  + D+S I  C IS++M+PY GFEA  +R      W PH+R G Y   RY+++ FG  K  +   +    +  NKP  L ++ TMDGRA++ ++ I+IS Y   + A  ++  P    RG+RV +   +  D    +  DLFGC      D+  FDPC+ + Y            R YLY   T+  ++ CD + + +  L    +C+R+ +A    W  LG  VG ++ + + +  +Y  A       +D +SY+ SEDNG+TW+  N   ++  +   +S  +P+    V+ WT    F    +G NCT Y     +  CYDGIY+ TS++ SWN+CC+ 
Sbjct:   47 FKGSRCDQLDNALPTFDTERYSASLPEGAAVGYRVTTVSAKDSDAATKPNCQCAKVIYTLEPSDNPRGFFAVDPNTGAVTVAASG-LPEGLHRIKIRASNPGPF-----ATSGFVVTEVAIDVEAVKSRQRRAIPPAGNVTFKYAQTFPTNNVTHLRMGEKLAFQVDVLFPLGDTSMNMEIFSPDNETAAVIMICDVKIISVGSRLNLNVTEVMSKATYEGKNNGSWPYVRVALPFGTVTHS-SGATVESDYTVSVAYEAVFLYNNIVSNNTEYWVSAGAEYNNESVIWIGQTSFLANTDKTDVATAKETPSINITGDSEIYPGTVSSFNLDFTVP--YLYSNFTLDVFGPLNDTEILSVCGIYTTASSGEGFGCMPRSSWPYEFTLSKQKASATNYYQSTLSFTSTLFTNKAYYKPGAT-TDDHRVSFAFAVKPNESAAVGNPTYVGASVDIGGTTVLSAYKTLQVANASLAPAAQNSTTVDPI-------ISLTRIGPGVLGRDQSTMFELALDTVPGI-FDYEIQALMPSNNSLGRLKICSMNVTYAGRNIPCLSQRMTSIAARYQILYSNDSVPSDQYDYAVISLPKLYNTGSVTTSQDPLANRVTVRMV-ATVNNHTLNVDGESAYVTMGVSYADKQWVG-INQINF----TNVVNISSLPNESLPIVSLSYVLGDSYFNLYETAVIEAVTELRRGVSYAPMDFEFIAPYMNDSAVMTVCRAEVIFVGKYIGCSDKSSLINNIRLTSK-NNSTRYDKAVFSLGTTSNVGPSTSIDSSTINDRIVLRFHVKMLDHVAHASGNGSSYSLSFGFQFSTDQIWIGQLP-AVLTKPEIPLPTLAADKTPYVT-FDVTNLTAYPLDAQSAGLLIKFPSGSVSSYTLKL-----IAPSFGSVCAATFVFTGGNISCVNETSVEESVQRNLYNSSDKEFLALSSTYNLGY--IHNAGEFTLVKDTNTDANTLKLRVSFRTASDAAAAATGDLVAQVFYSGSSTPVEAKVGVTIASG-ARPVTLTNETAPTFSMSIVPLIEGMPNS--SQFAPGQGFRARLTVTTKPNSVQRLEIRFVSPVDTTSTNVVDLLDAGVVSAGKNLPCTIPWADASTATKRNGSLAYDTVAVNLGVVCNYP--AGSSEADNQIAIDLFGRVWTSSPAMPDGDILLSTVAFISDQQINVNQINITVNQSATP--PQFSLTGNSTAINASFEHTDDIYVKVGEYAEVKMLLQVP---EFFSSLFKLDIRNADTNLSAWATINVVNITQSGGNMMGL-ANEPYILNRTSSLGTFQLDSAELLVYTVQNSGLSSLKNSRFPS--NATNNFTVTYSIKLADHPNANNDSVFQMSLGLHLLDRIVVGLRDIKVMRDNTEWPNGTVSVNISSLPASIYSAGEIVTLYVNVSCSNWSSAELQNAVLFLHTPPYIKLVNMSNIQYASGSISAVERPDGGMKFAFNNTIFLAE---TVQFEINVAMKENFILPGNRETANATSVYEFVYKMFDRAGNLNSARWYRKAGSVFFQVRG--APAPPDGCNLDFGMNDTSKISSCQISSFMAPYAGFEAHNVRPALAG-WKPHVRGGDYKNFRYVNVVFGYLKRISRIIVYADGASANKPTCLNLYKTMDGRAYTLHKTIDISGYYVGHVANFSV-QPRLVGRGVRVGVCDTSVQDAEVIVRFDLFGCNYSAELDSNAFDPCSRQPY------DNGHCGRSYLYLNDTSDTIYYCDHVPTSTEELTGISKCYRSTSAQNRKWTYLGPAVGSIVAYHADSNRLYGYAQGCYGNTTDDRSYLFSEDNGITWIPTNPESYKGTVAKASSSSTPLLYQKVVHWTVSAEFQSGVSGPNCTAYDAGNNWKICYDGIYHSTSKVVSWNSCCSL 1871
[Close]
BLAST of EGF-like domain-containing protein vs. TrEMBL
Match: A0A1I8IYA0 (EGF-like domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 378.252 bits (970), Expect = 1.869e-102
Identity = 409/1593 (25.67%), Postives = 717/1593 (45.01%), Query Frame = 2 
Query:  509 FTGPTCALFSNKLPHFEKSSYHLVFNESKKDTTPVIKVTAIDEDKCVRGNCECGEIIYSIL-EENAKELFEINSSSGEIKVIQGAVIPETKYSFSVKVTNRNPFD-DRYDTATIFVNGDSSNEILERHRRATAPT-KPAFELIQTFPIQNLTSINIGQRLSMQLSVAFPVGTTTLSVELFAPESQSYPVMMICDVNVISVGSLL---TTNSYNPPLQEGINGTVWPYTHIVYNFTNVINAQSSVTSLADIQIVITFDVVMLYSPNTTDGATYYVSGGSEYLNGTEIWVGQLGYIAN-----LXXXXXXXXXXXXGDTLVYPGRTAAFVLTIQAPDSYLYLN--LGIYSPLNNSVALSLC-VVNRYYVGAAYSCLPTNY--NQPTLKQVTINNQIYYTSAL-MNLGILGNRYYMEPTHTDMNEKTINISITARISPTLWLGTYQYIGLSISNTLTTIYT--KTYQVLVSPAPQLTAYTSPISYSLGYHKNITSVSIGSPGRININISIPTGTEL-DYTIIARSPENTS----EICGVIFFKAGLNIPCVDQ----ITFGTTYVYTPD-------NFATTSITSIGGIRHVKISNNTDDDILQLVLVFRPINDSRNSVNGIT---NIGVKV---NWTGSTGTENFLPVTLNAPDVSSANSTTLPTFTFQLXXXXXXXXXXXXYKLFFAMRLYPGTIYTPTSLEFYMPF-NGTIRVGMCKASITYVGKNVLCFNPTFITKSFIFSSKINDTSNYDKLLIPTGVLCTSGSSSAAPS--INDEIQISINILILPHAMNTV--GATANLNGGMMISSTQIWVGNQPLTFITIPAIXXXXXXXXXXXFAQRVDSTSSNVWINDMVIIQYIIKVAPAVVTRMTLSISTDATVATNNFGVCQVKIINQGLSIPCVNGT---------LTTTPATAFSKFYVSGNFAFTDILNTGTVALVANPTFDENSLLVEVIVKLGP--TLPPSFNVIASLTSNGAT--ASANVPLTFTSAFSRFNGTVASTEPVFNMFLYPLFNDT-NAVINNIAYSEAMRSVVSVEMKPNVLQSLKIVFASTPNI--VNQMDVISVNILSVGRNIPCLQKGMIPFSIQQRSNSLSKDLASIDMGTICHRPYLDNTTVEDNKIYIESVFRIW-KFPATSPLTLQINVLGLLNNDQVYVTR--IVFNTSTTPFVTDFSLTGESFNANATISSAS---VAVGGNFTVKVMVTIPPYTQFKSGTITVGNQNPVGSDSFYFINGNANFSGTSGQNIGINKDEPMPFTLKSTFNTSQLDNIVADLGVVQNTATTYRMNQVNYSAXXXXXXXXXXXXXQLTDNSMASNGQIINFIVGVSFGSKTLNFSLQITVLRINNETMDFXXXXXXXXXXXXXXXXXPIIASAQAIML-NTSTLECRNFSIFVAAPPFIQLSSVVNTSYTSPGYPTVAKNIPIAGFSFNVPYFFYKENITIIFTMSVIAGLN--LTKGRAQSSITIPVVYSCQTLNWPLNPMGNKYFNKVETLVFTVKGXXXXXXXXXXXXXXXXKDSSVIQDCAISAYMSPYPGFEATKIRSNSGSY---WVPHIRSGQYNKLRYIDIKFG 5065
            F G  C    N LP F+   Y     E       V  V+A D D   + NC+C ++IY++   +N +  F ++ ++G + V     +PE  +   ++ +N  PF    +    + ++ ++   +  R RRA  P     F+  QTFP  N+T + +G++L+ Q+ V FP+G T++++E+F+P++++  V+MICDV +ISVGS L    T   +    EG N   WPY  +   F  V ++ S  T  +D  + + ++ V LY+   ++   Y+VS G+EY N + IW+GQ  ++AN     ++T    P+I+ITGD+ +YPG  ++F L    P  YLY N  L ++ PLN++  LS+C +      G  + C+P +    + TL +   +   YY S L     +  N+ Y +P  T  ++  ++ +   + + +  +G   Y+G S+    TT+ +  KT Q  V P   LT               I    +G        +++ T   + DY I A  P N S    +IC +    AG NIPC+ Q    I      +Y+ D       ++A  S+  +     V  S +   + + + +V   +N+   +V+G +    +GV      W G     NF     N  ++SS  + +LP  +      D   ++     +     L  G  Y P   EF  P+ N +  + +C+A + +VGK + C + +    S I + ++   + YDK +   G     G S++  S  IND I +  ++ +L H  +    G++ +L+ G   S+ QIW+G  P   +T P IP    ++    +    D T+   +  D      +IK     V+  TL +     +A +   VC    +  G +I CVN T         L  +    F     + N  +  I N G   LV +   D N+L + V  +  P  +   + +++A +  +G++    A V +T  S  +R       T P F+M + PL     N+  +  A  +  R+ ++V  KPN +Q L+I F S  +    N +D++   ++S G+N+PC        +  +R+ SL+ D  ++++G +C+ P    ++  DN+I I+   R+W   PA     + ++ +  +++ Q+ V +  I  N S TP    FSLTG S   NA+    +   V VG    VK+++ +    +F S    +  +N   + S +      N + + G  +G+  +EP      S+  T QLD+    +  VQN+  +   N    S     +  TVT  ++L D+  A+N  +    +G+    + +     I V+R N E  +   S N+ +      S   I+     +   N S+ E +N  +F+  PP+I+L ++ N  Y S G   V +      F+FN   F  +   T+ F ++V    N  L   R  ++ T    +  +  +   N    +++ K  ++ F V+G               + D+S I  C IS++M+P         R+ SG     W PH+R G Y   RY+++ FG
Sbjct:  219 FKGSRCDQLDNALPTFDTERYSASLPEGAAVGYRVTTVSAKDSDAATKPNCQCAKVIYTLEPSDNPRGFFAVDPNTGAVTVAASG-LPEGLHRIKIRASNPGPFATSGFVVTEVAIDVEA---VKSRQRRAIPPAGNVTFKYAQTFPTNNVTHLRMGEKLAFQVDVLFPLGDTSMNMEIFSPDNETAAVIMICDVKIISVGSRLNLNVTEVMSKATYEGKNNGSWPYVRVALPFGTVTHS-SGATVESDYTVSVAYEAVFLYNNIVSNNTEYWVSAGAEYNNESVIWIGQTSFLANTDKTDVATAKETPSINITGDSEIYPGTVSSFNLDFTVP--YLYSNFTLDVFGPLNDTEILSVCGIYTTASSGEGFGCMPRSSWPYEFTLSKQKASATNYYQSTLSFTSTLFTNKAYYKPGAT-TDDHRVSFAFAVKPNESAAVGNPTYVGASVDIGGTTVLSAYKTLQTTVDPIISLT--------------RIGPGVLGRDQSTMFELALDTVPGIFDYEIQALMPSNNSLGRLKICSMNVTYAGRNIPCLSQRMTSIAARYQILYSNDSVPSDQYDYAVISLPKLYNTGSVTTSQDPLANRVTVRMV-ATVNNHTLNVDGESAYVTMGVSYADKQWVG-INQINF----TNVVNISSLPNESLPIVSLSYVLGDSYFNLYETAVIEAVTELRRGVTYAPMDFEFIAPYMNDSAVMTVCRAEVIFVGKYIGCSDKS----SLINNIRLTSNTRYDKAVFSLGTTSNVGPSTSIDSSTINDRIVLRFHVKMLDHVAHASGNGSSYSLSFGFQFSTDQIWIGQLP-AVLTKPEIPLPTLAADKTPYVT-FDVTNLTAYPLDAQSAGLLIKFPSGSVSSYTLKL-----IAPSFGSVCAATFVFTGGNISCVNETSVEESVQRNLYNSSDKEFLALSSTYNLGY--IHNAGEFTLVKDTNTDANTLKLRVSFRTAPDASAGATGDLVAQVFYSGSSTPVEAKVGVTIASG-ARPVTLTNETAPTFSMSIVPLIEGMPNS--SQFAPGQGFRARLTVTTKPNSVQRLEIRFVSPVDTTSTNVVDLLDAGVVSAGKNLPCTIPWADASTATKRNGSLAYDTVAVNLGVVCNYPA--GSSEADNQIAIDLFGRVWTSSPAMPDGNILLSTVAFISDQQINVNQINITVNQSATP--PQFSLTGNSTAINASFEHTNDIYVKVGEYAEVKMLLQV---QEFFSSLFKLDIRNADTNLSAWATINVVNITQSGGNMMGL-ANEPYILNRTSSLGTFQLDSAELLVYTVQNSGLSSLKNSRFPS--NATNNFTVTYSIKLADHPNANNDSVFQMSLGLHLLDRIVVGLRDIKVMRDNTEWPNGTVSVNISSLPASIYSAGEIVTLYVNVSCSNWSSAELQNAVLFLHTPPYIKLVNMSNIQYASGGISAVERPDGGMKFAFNNTIFLAE---TVQFEINVAMKENFILPGNRETANATSVYEFVYKMFDRAGNLNSARWYRKAGSVFFQVRGAPAPPDGRLQPGLRPMNDTSKISSCQISSFMAP---LTPASRRTMSGRLRPGWKPHVRGGDYKNFRYVNVVFG 1751
[Close]
BLAST of EGF-like domain-containing protein vs. TrEMBL
Match: A0A1I8GIG5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 309.301 bits (791), Expect = 5.925e-82
Identity = 346/1360 (25.44%), Postives = 598/1360 (43.97%), Query Frame = 2 
Query: 1988 LDYTIIARSPENTS----EICGVIFFKAGLNIPCVDQ----ITFGTTYVYTPD-------NFATTSITSIGGIRHVKISNNTDDDILQLVLVFRPINDSRNSVNGIT---NIGVKV---NWTGSTGTENFLPVTLNAPDVSSANSTTLPTFTFQLXXXXXXXXXXXXYKLFFAMRLYPGTIYTPTSLEFYMPF-NGTIRVGMCKASITYVGKNVLCFNPTFITKSFIFSSKINDTSNYDKLLIPTGVLCTSGSSSAAPS--INDEIQISINILILPHAMNTVG--ATANLNGGMMISSTQIWVGNQPLTFITIPAIXXXXXXXXXXXFAQRVDSTSSNVWINDMVIIQYIIKVAPAVVTRMTLSISTDATVATNNFGVCQVKIINQGLSIPCVNGT---------LTTTPATAFSKFYVSGNFAFTDILNTGTVALVANPTFDENSLLVEVIVKLGP--TLPPSFNVIASLTSNGAT--ASANVPLTFTSAFSRFNGTVASTEPVFNMFLYPLFNDT-NAVINNIAYSEAMRSVVSVEMKPNVLQSLKIVFASTPNIV--NQMDVISVNILSVGRNIPCLQKGMIPFSIQQRSNSLSKDLASIDMGTICHRPYLDNTTVEDNKIYIESVFRIW-KFPATSPLTLQINVLGLLNNDQVYVTR--IVFNTSTTPFVTDFSLTGESFNANATISSAS---VAVGGNFTVKVMVTIPPYTQFKSGTITVGNQNPVGSDSFYFINGNANFSGTSGQNIGINKDEPMPFTLKSTFNTSQLDNIVADLGVVQNTATTYRMNQVNYSAXXXXXXXXXXXXXQLTDNSMASNGQIINFIVGVSFGSKTLNFSLQITVLRINNETMDFXXXXXXXXXXXXXXXXXPIIASAQAIML-NTSTLECRNFSIFVAAPPFIQLSSVVNTSYTSPGYPTVAKNIPIAGFSFNVPYFFYKENITIIFTMSVIAGLN--LTKGRAQSSITIPVVYSCQTLNWPLNPMGNKYFNKVETLVFTVKGXXXXXXXXXXXXXXXXKDSSVIQDCAISAYMSPYPGFEATKIRSNSGSYWVPHIRSGQYNKLRYIDIKFGKLXXXXXXXXXXXXGNKPQTLGIHGTMDGRAFSFYQNINISYNPDNTAAVTLNNPPFTYRGIRVSIVVANQDDINTGMNLDLFGCLPPNVTDTFTFDPCATKSYLVPTNPLPEFYYRGYLY---TNQQLFVCDEIVSLSFGLETYPRCFRTNTATFTTWEDLGNQVGKVIGFDSVNMIIYAIA-------SDIKSYIMSEDNGLTWVGINGGGWQ-IMKNTASLQSPI----VIPWTNDTTFDYLTTGNNCTKYTVA-TFNFCYDGIYNGTSRIFSWNNCCNF 5866
             DY I A  P N S    +IC +    AG NIPC+ Q    I      +Y+ D       ++A  S+  +     V  S +   + + + +V   +N+   +V+G +    +GV      W G     NF     N  ++SS  + +LP  +      D   ++     +     L  G  Y P   EF  P+ N +  + +C+A + +VGK + C + + +  +   +SK N+++ YDK +   G     G S++  S  IND I +  ++ +L H  +  G  ++ +L+ G   S+ QIW+G  P   +T P IP    ++    +    D T+   +  D      +IK     V+  TL +     +A +   VC    +  G +I CVN T         L  +    F     + N  +  I N G   LV +   D N+L + V  +  P  +   + +++A +  +G++    A V +T  S  +R       T P F+M + PL     N+  +  A  +  R+ ++V  KPN +Q L+I F S  +    N +D++   ++S G+N+PC        +  +R+ SL+ D  ++++G +C+ P    ++  DN+I I+   R+W   PA     + ++ +  +++ Q+ V +  I  N S TP    FSLTG S   NA+        V VG    VK+++ +P   +F S    +  +N   + S +      N + + G  +G+  +EP      S+  T QLD+    +  VQN+  +   N    S     +  TVT  ++L D+  A+N  +    +G+    + +     I V+R N E  +   S N+ +      S   I+     +   N S+ E +N  +F+  PP+I+L ++ N  Y S     V +      F+FN   F  +   T+ F ++V    N  L   R  ++ T    +  +  +   N    +++ K  ++ F V+G         CN D  + D+S I  C IS++M+PY GFEA  +R      W PH+R G Y   RY+++ FG L  +++I++                + G       N ++              P    RG+RV +   +  D    +  DLFGC      D+  FDPC+ + Y            R YLY   T+  ++ CD + + +  L    +C+R+ +A    W  LG  VG ++ + + +  +Y  A       +D +SY+ SEDNG+TW+  N   ++  +   +S  +P+    V+ WT    F    +G NCT Y     +  CYDGIY+ TS++ SWN+CC+ 
Sbjct:   13 FDYEIQALMPSNNSLGRLKICSMNVTYAGRNIPCLSQRMTSIAARYQILYSNDSVPSDQYDYAVISLPKLYNTGSVTTSQDPLANRVTVRMV-ATVNNHTLNVDGESAYVTMGVSYADKQWVG-INQINFT----NVVNISSLPNESLPIVSLSYVLGDSYFNLYETAVIEAVTELRRGVTYAPMDFEFIAPYMNDSAVMTVCRAEVIFVGKYIGCSDKSSLINNIRLTSK-NNSTRYDKAVFSLGTTSNVGPSTSIDSSTINDRIVLRFHVKMLDHVAHASGNGSSYSLSFGFQFSTDQIWIGQLP-AVLTKPEIPLPTLAADKTPYVT-FDVTNLTAYPLDAQSAGLLIKFPSGSVSSYTLKL-----IAPSFGSVCAATFVFTGGNISCVNETSVEESVQRNLYNSSDKEFLALSSTYNLGY--IHNAGEFTLVKDTNTDANTLKLRVSFRTAPDASAAATGDLVAQVFYSGSSTPVEAKVGVTIASG-ARPVTLTNETAPTFSMSIVPLIEGMPNS--SQFAPGQGFRARLTVTTKPNSVQRLEIRFVSPVDTTSTNVVDLLDAGVVSAGKNLPCTIPWADASTATKRNGSLAYDTVAVNLGVVCNYP--AGSSEADNQIAIDLFGRVWTSSPAMPDGDILLSTVAFISDQQINVNQINITVNQSATP--PQFSLTGNSTAINASFEHTDDIYVKVGEYAEVKMLLQVP---EFFSSLFKLDIRNADTNLSAWATINVVNITQSGGNMMGL-ANEPYILNRTSSLGTFQLDSAELLVYTVQNSGLSSLKNSRFPS--NATNNFTVTYSIKLADHPNANNDSVFQMSLGLHLLDRIVVGLRDIKVMRDNTEWPNGTVSVNISSLPASIYSAGEIVTLYVNVSCSNWSSAELQNAVLFLHTPPYIKLVNMSNIQYASGSISAVERPDGGMKFAFNNTIFLAE---TVQFEINVAMKENFILPGNRETANATSVYEFVYKMFDRAGNLNSARWYRKAGSVFFQVRG--APAPPDGCNLDFGMNDTSKISSCQISSFMAPYAGFEAHNVRPALAG-WKPHVRGGDYKNFRYVNVVFGYLKRISRIII---------------DISGYYVGHVANFSV-------------QPRLVGRGVRVGVCDTSVQDAEVIVRFDLFGCNYSAELDSNAFDPCSRQPY------DNGHCGRSYLYLNDTSDTIYYCDHVPTSTEELTGISKCYRSTSAQNRKWTYLGPAVGSIVAYHADSNRLYGYAQGCYGNTTDDRSYLFSEDNGITWIPTNPESYKGTVAKASSSSTPLLYQKVVHWTVSAEFQSGVSGPNCTAYDAGNNWKICYDGIYHSTSKVVSWNSCCSL 1303
[Close]
BLAST of EGF-like domain-containing protein vs. Planmine SMEST
Match: SMESG000009899.1 (SMESG000009899.1)

HSP 1 Score: 3395.91 bits (8804), Expect = 0.000e+0
Identity = 1811/1829 (99.02%), Postives = 1818/1829 (99.40%), Query Frame = 2 
Query:  380 MNRQXXXXXXXXXXNRICYGEXXXXXXXXXXXXXXXXXXXKECFTGPTCALFSNKLPHFEKSSYHLVFNESKKDTTPVIKVTAIDEDKCVRGNCECGEIIYSILEENAKELFEINSSSGEIKVIQGAVIPETKYSFSVKVTNRNPFDDRYDTATIFVNGDSSNEILERHRRATAPTKPAFELIQTFPIQNLTSINIGQRLSMQLSVAFPVGTTTLSVELFAPESQSYPVMMICDVNVISVGSLLTTNSYNPPLQEGINGTVWPYTHIVYNFTNVINAQSSVTSLADIQIVITFDVVMLYSPNTTDGATYYVSGGSEYLNGTEIWVGQLGYIANLXXXXXXXXXXXXGDTLVYPGRTAAFVLTIQAPDSYLYLNLGIYSPLNNSVALSLCVVNRYYVGAAYSCLPTNYNQPTLKQVTINNQIYYTSALMNLGILGNRYYMEPTHTDMNEKTINISITARISPTLWLGTYQYIGLSISNTLTTIYTKTYQVLVSPAPQLTAYTSPISYSLGYHKNITSVSIGSPGRININISIPTGTELDYTIIARSPENTSEICGVIFFKAGLNIPCVDQITFGTTYVYTPDNFATTSITSIGGIRHVKISNNTDDDILQLVLVFRPINDSRNSVNGITNIGVKVNWTGSTGTENFLPVTLNAPDVSSANSTTLPTFTFQLXXXXXXXXXXXXYKLFFAMRLYPGTIYTPTSLEFYMPFNGTIRVGMCKASITYVGKNVLCFNPTFITKSFIFSSKINDTSNYDKLLIPTGVLCTSGSSSAAPSINDEIQISINILILPHAMNTVGATANLNGGMMISSTQIWVGNQPLTFITIPAIXXXXXXXXXXXFAQRVDSTSSNVWINDMVIIQYIIKVAPAVVTRMTLSISTDATVATNNFGVCQVKIINQGLSIPCVNGTLTTTPATAFSKFYVSGNFAFTDILNTGTVALVANPTFDENSLLVEVIVKLGPTLPPSFNVIASLTSNGATASANVPLTFTSAFSRFNGTVASTEPVFNMFLYPLFNDTNAVINNIAYSEAMRSVVSVEMKPNVLQSLKIVFASTPNIVNQMDVISVNILSVGRNIPCLQKGMIPFSIQQRSNSLSKDLASIDMGTICHRPYLDNTTVEDNKIYIESVFRIWKFPATSPLTLQINVLGLLNNDQVYVTRIVFNTSTTPFVTDFSLTGESFNANATISSASVAVGGNFTVKVMVTIPPYTQFKSGTITVGNQNPVGSDSFYFINGNANFSGTSGQNIGINKDEPMPFTLKSTFNTSQLDNIVADLGVVQNTATTYRMNQVNYSAXXXXXXXXXXXXXQLTDNSMASNGQIINFIVGVSFGSKTLNFSLQITVLRINNETMDFXXXXXXXXXXXXXXXXXPIIASAQAIMLNTSTLECRNFSIFVAAPPFIQLSSVVNTSYTSPGYPTVAKNIPIAGFSFNVPYFFYKENITIIFTMSVIAGLNLTKGRAQSSITIPVVYSCQTLNWPLNPMGNKYFNKVETLVFTVKGXXXXXXXXXXXXXXXXKDSSVIQDCAISAYMSPYPGFEATKIRSNSGSYWVPHIRSGQYNKLRYIDIKFGKLXXXXXXXXXXXXGNKPQTLGIHGTMDGRAFSFYQNINISYNPDNTAAVTLNNPPFTYRGIRVSIVVANQDDINTGMNLDLFGCLPPNVTDTFTFDPCATKSYLVPTNPLPEFYYRGYLYTNQQLFVCDEIVSLSFGLETYPRCFRTNTATFTTWEDLGNQVGKVIGFDSVNMIIYAIASDIKSYIMSEDNGLTWVGINGGGWQIMKNTASLQSPIVIPWTNDTTFDYLTTGNNCTKYTVATFNFCYDGIYNGTSRIFSWNNCCNF 5866
            MNRQIFLIFLILIFNRICYGEVCGNDDCVNGVCVNDVCVCKECFTGPTCALFSNKLPHFEKSSYHLVFNESKKDTTPVIKVTAIDEDKCVRGNCECGEIIYSILEENAKELFEINSSSGEIKVIQGAVIPETKYSFSVKVTNRNPFDDRYDTATIFVNGDSSNEILERHRRATAPTKPAFELIQTFPIQNLTSINIGQRLSMQLSVAFPVGTTTLSVELFAPESQSYPVMMICDVNVISVGSLLTTNSYNPPLQEGINGTVWPYTHIVYNFTNVIN+QSSVTSLADIQIVITFDVVMLYSPNTTDGATYYVSGGSEYLNGTEIWVGQLGYIANLSTPTINPTISITGDTLVYPGRTAAFVLTIQAPDSYLYLNLGIYSPLNNSVALSLCVVNRYYVGAAYSCLPTNYNQPTLKQVTINNQIYYTSALMNLGILGNRYYMEPTHTDMNEKTINISITARISPTLWLGTYQYIGLSISNTLTTIYT+TYQVLVSPAPQLTAYTSPISYSLGYHKNITSVSIGSPGRININISIPTGTELDYTIIARSPENTSEICGVIFFKAGLNIPCVDQITFGTTYVYTPDNFATTSITSIGGIRHVKISNNTDDDILQLVLVFRPINDSRNSVNGITNIGVKVNWTGSTGTEN LPVTLNAPDVSSANSTTLPTFTFQLNGNDGNVSVNGNYKLFFAMRLYPGTIYTPTSLEFYMPFNGTIRVGMCKASITYVGKNVLCFNPTFITKSF+FSSKINDTSNYDKLLIPTGVLCTSGSSSAAPSINDEIQISINILILPHAMNTVGATANLNGGMMISSTQIWVGNQPLTFIT+PAIPSLNSSSSPLLFAQRVDSTSSNVWINDMVIIQYIIKVAPAVVTRMTLSISTDATVATNNFGVCQVKIINQGLSIPCVNGTLTTTPATAFSKFYVSGNFAFTDILNTGTVALVANPTFDENSLLVEVIVKLGPTLPPSFNVIASLTSNGATASANVPLTFTSAFSRFNGTVASTEPVFNMFLYPLFNDTNAVINNIAYSEAMRSVVSVEMKPNVLQSLKIVFASTPN +NQMDVISVNILSVGRNIPCLQKGMIPFSIQQRSNSLSKDLASIDMGTICHRPYLDNTTVEDNKIYIESVFRIWKFPATSPLTLQINVLGLLNNDQVYVTRIVFNTSTTPFVTDFSLTGESFNANATISSASVAVGGNFTVKVMVTIPPYTQFKSGTITVGNQNPVGSDSFYFINGNANFSGTSGQNIGINKDEPMPFTLKSTFNTSQLDNIVADLGVVQNTATTYRMNQVNYSAPTPDDTLTVTLPVQLTDNSMASNGQIINFIVGVSFGSKTLNFSLQITVLRINNETMDFNTSTNLLTSNNIYTSTTPIIASAQAIMLNTSTLECRNFSIFVAAPPFIQLSSVVNTSYTSPGYP VAKNIPIAGFSFNVPYFFYKENITIIFTMSVIAGLNLTKGRAQSSITIPVVYSCQTLNWPLNPMGNKYFNKVETLVFTVKG   +     CNNDLNLKDSSVIQDCAISAYMSPYPGFEATKIRSNSGSYWVPHIRSGQYNKLRYIDIKFGKLTTVTK+VVTSSIGNKPQTLGIHGTMDGRAFSFYQNINISYNPDNTAAVTLNNPPFTYRGIRVSIVVANQDDINTGMNLDLFGCLPPNVTDTFTFDPCATKSYLVPTNPLPEFYYRGYLYTNQQLFVCDEIVSLSFGLETYPRCFRTNTATFTTWEDLGNQVGKVIGFDSVNMIIYAIASDIKSYIMSEDNGLTWVGINGGGWQIMKNTASLQSPIVIPWTNDTTFDYLTTGNNCTKYTVATFNFCYDGIYNGTSRIFSWNNCCNF
Sbjct:    1 MNRQIFLIFLILIFNRICYGEVCGNDDCVNGVCVNDVCVCKECFTGPTCALFSNKLPHFEKSSYHLVFNESKKDTTPVIKVTAIDEDKCVRGNCECGEIIYSILEENAKELFEINSSSGEIKVIQGAVIPETKYSFSVKVTNRNPFDDRYDTATIFVNGDSSNEILERHRRATAPTKPAFELIQTFPIQNLTSINIGQRLSMQLSVAFPVGTTTLSVELFAPESQSYPVMMICDVNVISVGSLLTTNSYNPPLQEGINGTVWPYTHIVYNFTNVINSQSSVTSLADIQIVITFDVVMLYSPNTTDGATYYVSGGSEYLNGTEIWVGQLGYIANLSTPTINPTISITGDTLVYPGRTAAFVLTIQAPDSYLYLNLGIYSPLNNSVALSLCVVNRYYVGAAYSCLPTNYNQPTLKQVTINNQIYYTSALMNLGILGNRYYMEPTHTDMNEKTINISITARISPTLWLGTYQYIGLSISNTLTTIYTRTYQVLVSPAPQLTAYTSPISYSLGYHKNITSVSIGSPGRININISIPTGTELDYTIIARSPENTSEICGVIFFKAGLNIPCVDQITFGTTYVYTPDNFATTSITSIGGIRHVKISNNTDDDILQLVLVFRPINDSRNSVNGITNIGVKVNWTGSTGTENVLPVTLNAPDVSSANSTTLPTFTFQLNGNDGNVSVNGNYKLFFAMRLYPGTIYTPTSLEFYMPFNGTIRVGMCKASITYVGKNVLCFNPTFITKSFVFSSKINDTSNYDKLLIPTGVLCTSGSSSAAPSINDEIQISINILILPHAMNTVGATANLNGGMMISSTQIWVGNQPLTFITLPAIPSLNSSSSPLLFAQRVDSTSSNVWINDMVIIQYIIKVAPAVVTRMTLSISTDATVATNNFGVCQVKIINQGLSIPCVNGTLTTTPATAFSKFYVSGNFAFTDILNTGTVALVANPTFDENSLLVEVIVKLGPTLPPSFNVIASLTSNGATASANVPLTFTSAFSRFNGTVASTEPVFNMFLYPLFNDTNAVINNIAYSEAMRSVVSVEMKPNVLQSLKIVFASTPNSLNQMDVISVNILSVGRNIPCLQKGMIPFSIQQRSNSLSKDLASIDMGTICHRPYLDNTTVEDNKIYIESVFRIWKFPATSPLTLQINVLGLLNNDQVYVTRIVFNTSTTPFVTDFSLTGESFNANATISSASVAVGGNFTVKVMVTIPPYTQFKSGTITVGNQNPVGSDSFYFINGNANFSGTSGQNIGINKDEPMPFTLKSTFNTSQLDNIVADLGVVQNTATTYRMNQVNYSAPTPDDTLTVTLPVQLTDNSMASNGQIINFIVGVSFGSKTLNFSLQITVLRINNETMDFNTSTNLLTSNNIYTSTTPIIASAQAIMLNTSTLECRNFSIFVAAPPFIQLSSVVNTSYTSPGYPPVAKNIPIAGFSFNVPYFFYKENITIIFTMSVIAGLNLTKGRAQSSITIPVVYSCQTLNWPLNPMGNKYFNKVETLVFTVKG--NDVNNTACNNDLNLKDSSVIQDCAISAYMSPYPGFEATKIRSNSGSYWVPHIRSGQYNKLRYIDIKFGKLTTVTKMVVTSSIGNKPQTLGIHGTMDGRAFSFYQNINISYNPDNTAAVTLNNPPFTYRGIRVSIVVANQDDINTGMNLDLFGCLPPNVTDTFTFDPCATKSYLVPTNPLPEFYYRGYLYTNQQLFVCDEIVSLSFGLETYPRCFRTNTATFTTWEDLGNQVGKVIGFDSVNMIIYAIASDIKSYIMSEDNGLTWVGINGGGWQIMKNTASLQSPIVIPWTNDTTFDYLTTGNNCTKYTVATFNFCYDGIYNGTSRIFSWNNCCNF 1827
The following BLAST results are available for this feature:
BLAST of EGF-like domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EGF-like domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EGF-like domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EGF-like domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EGF-like domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EGF-like domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EGF-like domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EGF-like domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267GA836.767e-15427.06EGF-like domain-containing protein OS=Macrostomum ... [more]
A0A267F0692.091e-15227.00EGF-like domain-containing protein OS=Macrostomum ... [more]
A0A267GYV56.291e-15126.90EGF-like domain-containing protein OS=Macrostomum ... [more]
A0A1I8IYA01.869e-10225.67EGF-like domain-containing protein OS=Macrostomum ... [more]
A0A1I8GIG55.925e-8225.44Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of EGF-like domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EGF-like domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EGF-like domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EGF-like domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EGF-like domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EGF-like domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000009899.10.000e+099.02SMESG000009899.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30000129 ID=SMED30000129|Name=EGF-like domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=6167bp
ATTGAGAGGATTGCTCGTTGAAAACAAAAGTCTAAGTTTAGAAAATTGTA
TTTCGATTCTCTCTCGTCTCGAAAGGCGAAATAAGGGGGAAAATAAAAGG
AAATGCAAATAATTCCAATTGCAAGAGTTTTGTTGTTATTTGCAGATAGT
AGTTGCCATGAATATTTCATTGTTATTTCTGGTAGGCATCACTGACGTAG
CCAAGTAACATGCAGCGATAAATAAACAAAGTTCTGTATGTCTTGTAGAG
TTTTCTAGCTCTACCAATTCTCTCAATTCAACAGGTAGAACTGTAAACAA
TAAATTTCATTTTTATTCCAACTAATACAAATATCTTCATTTTCTTAATC
TGCCTTTATTTTATTTTGGGAATTTTATCATGAATCGACAAATCTTTCTC
ATATTCCTAATTTTGATTTTCAATCGAATCTGCTATGGGGAAGTTTGCGG
AAATGACGATTGCGTAAACGGTGTTTGCGTAAATGATGTTTGTGTGTGTA
AAGAGTGTTTTACCGGACCGACGTGTGCATTATTCTCAAACAAACTCCCG
CATTTTGAGAAAAGTTCGTACCATTTGGTCTTCAACGAAAGTAAGAAAGA
TACAACTCCTGTAATTAAAGTTACTGCAATTGACGAGGATAAATGTGTTA
GAGGAAATTGTGAATGTGGAGAAATTATCTATTCTATTTTGGAGGAAAAT
GCCAAAGAATTATTTGAAATCAATTCAAGTTCTGGTGAAATTAAAGTCAT
TCAAGGAGCGGTAATTCCTGAAACGAAATATAGTTTTTCTGTCAAAGTCA
CGAACAGAAATCCATTCGATGATAGATATGACACCGCCACCATTTTCGTT
AATGGCGATTCTTCTAATGAGATCCTTGAACGGCATCGTAGAGCGACAGC
TCCCACCAAGCCTGCGTTCGAGCTCATTCAAACTTTCCCCATTCAAAATT
TAACTTCAATTAATATTGGTCAAAGATTGAGTATGCAGTTAAGTGTTGCG
TTTCCTGTGGGGACAACGACACTCAGTGTTGAATTATTCGCTCCGGAAAG
TCAGTCATATCCGGTTATGATGATTTGCGATGTCAACGTGATTAGCGTCG
GTTCACTATTAACAACAAACTCATACAATCCTCCTTTACAAGAAGGTATC
AACGGAACAGTTTGGCCGTATACTCACATTGTGTATAATTTCACCAACGT
CATCAACGCCCAATCCAGTGTAACAAGTTTAGCTGACATTCAAATTGTCA
TTACATTCGACGTGGTGATGTTATACTCTCCGAATACAACGGATGGTGCT
ACGTATTACGTAAGCGGTGGATCCGAATATCTAAATGGAACAGAAATATG
GGTCGGTCAATTGGGATACATAGCAAACCTTTCAACTCCTACTATCAATC
CAACAATCAGTATCACTGGGGATACTTTGGTTTACCCTGGCCGAACAGCG
GCTTTTGTGTTGACAATCCAGGCCCCGGATTCATACTTGTATCTTAATTT
GGGAATCTACAGTCCACTGAATAATTCTGTGGCCCTTAGCCTATGCGTCG
TCAACCGGTATTACGTTGGGGCGGCCTATAGTTGTCTACCGACAAACTAT
AATCAACCAACTCTGAAACAAGTAACCATTAATAATCAGATATATTATAC
GTCAGCTTTAATGAATTTGGGAATTCTGGGAAATAGATATTACATGGAGC
CTACTCATACGGATATGAATGAGAAAACAATAAATATTTCGATAACAGCT
CGGATTAGTCCAACTTTATGGCTCGGCACTTACCAATATATTGGGCTCTC
CATCAGCAATACGTTGACAACAATCTATACTAAAACCTACCAAGTTTTAG
TCTCACCGGCTCCTCAATTGACGGCGTACACGAGTCCCATTTCTTATTCA
CTTGGTTATCACAAAAATATCACTTCGGTAAGTATCGGAAGCCCGGGACG
GATCAACATAAATATTTCAATACCCACCGGGACAGAACTCGATTACACAA
TAATTGCCAGGTCCCCTGAAAATACATCAGAGATTTGTGGGGTAATATTC
TTTAAAGCTGGATTGAATATCCCTTGCGTTGATCAAATTACATTCGGCAC
GACATACGTATATACGCCTGATAATTTTGCTACAACATCTATTACGTCAA
TCGGAGGAATCAGACATGTGAAAATCAGCAACAACACGGATGACGACATT
TTACAGCTCGTTTTGGTCTTTCGGCCGATAAATGATTCGAGAAATTCCGT
GAACGGGATCACTAATATTGGAGTCAAGGTTAATTGGACCGGTTCAACCG
GAACGGAAAACTTTTTGCCAGTGACCTTGAATGCCCCTGATGTGTCCAGC
GCAAATAGCACAACCTTACCAACCTTTACCTTTCAATTAAATGGCAACGA
TGGAAATGTTTCAGTCAATGGCAATTACAAACTGTTCTTCGCCATGAGAC
TTTATCCGGGCACGATTTATACTCCAACTTCTTTAGAATTCTATATGCCT
TTCAATGGGACCATTCGAGTGGGAATGTGCAAAGCTTCAATAACTTATGT
TGGAAAAAATGTTCTTTGTTTTAATCCAACATTTATTACCAAATCATTTA
TATTTTCTAGCAAAATTAATGATACGTCTAATTATGACAAATTGCTTATC
CCGACTGGAGTGCTGTGTACAAGTGGCTCCTCCTCCGCGGCCCCTTCCAT
AAACGATGAAATACAAATCTCAATTAACATCCTTATTTTACCACATGCTA
TGAATACAGTCGGGGCTACGGCTAATCTAAATGGCGGAATGATGATTTCC
TCAACACAAATCTGGGTAGGTAACCAGCCATTAACGTTTATTACCATCCC
GGCCATCCCAAGTTTAAATTCCTCCAGCAGTCCATTACTTTTTGCGCAGA
GAGTGGATTCTACTTCTAGTAATGTCTGGATTAATGATATGGTAATCATC
CAGTACATCATTAAAGTTGCCCCGGCTGTTGTAACTAGAATGACTCTTTC
CATCTCAACCGACGCTACAGTAGCAACTAACAATTTCGGAGTCTGTCAAG
TAAAAATCATAAACCAAGGCTTATCCATCCCCTGTGTTAATGGAACTCTG
ACAACCACTCCAGCGACGGCCTTTTCCAAGTTTTATGTTTCCGGCAATTT
TGCCTTTACAGATATTCTCAATACCGGCACAGTTGCACTGGTCGCAAACC
CGACTTTCGATGAAAACTCTCTTTTGGTAGAAGTGATAGTCAAACTTGGT
CCGACATTGCCACCTAGTTTCAATGTGATTGCATCTTTGACGTCAAATGG
TGCTACCGCATCAGCAAATGTTCCGCTAACTTTTACCTCAGCATTTAGCA
GATTTAATGGAACTGTGGCCTCCACGGAACCAGTTTTCAACATGTTCTTG
TATCCTCTATTCAACGATACGAATGCTGTAATAAATAACATTGCGTACAG
TGAAGCGATGAGAAGCGTCGTTAGCGTTGAAATGAAACCGAACGTACTGC
AAAGCCTAAAAATTGTATTTGCTTCAACCCCAAACATCGTAAATCAGATG
GACGTGATTAGCGTCAATATACTTTCAGTCGGTCGGAATATACCTTGTCT
GCAGAAAGGAATGATACCTTTCTCTATACAGCAAAGATCTAATTCTTTGT
CTAAGGACCTAGCTTCTATTGATATGGGGACTATCTGCCACAGGCCATAC
CTCGACAATACGACGGTTGAAGACAATAAAATTTACATCGAGTCTGTATT
TCGAATTTGGAAGTTTCCCGCGACCAGTCCTTTAACCTTGCAAATTAATG
TCTTGGGTTTGTTAAACAACGATCAAGTGTATGTAACGAGAATCGTATTC
AACACATCAACTACTCCGTTCGTCACCGATTTCAGCCTTACCGGTGAATC
TTTCAACGCAAATGCTACAATTTCCAGTGCCTCAGTGGCTGTTGGGGGTA
ATTTTACAGTTAAAGTGATGGTAACCATTCCACCATACACCCAATTCAAA
TCTGGAACAATAACAGTTGGTAACCAAAATCCGGTGGGATCAGATAGTTT
CTATTTCATAAACGGAAATGCAAATTTTTCTGGAACTTCTGGGCAAAATA
TTGGAATAAATAAGGATGAGCCAATGCCATTTACCTTGAAGTCCACTTTT
AATACGAGTCAATTAGATAACATAGTGGCAGATCTAGGAGTCGTCCAGAA
TACTGCAACAACTTACCGAATGAACCAGGTCAATTACTCTGCCCCGACAC
CTGATGATACGTTGACTGTAACGTTGCCGGTGCAGTTGACCGACAACTCG
ATGGCATCGAATGGTCAAATTATAAACTTCATTGTCGGCGTCTCTTTTGG
ATCGAAAACGCTAAACTTTTCTCTCCAAATCACAGTTTTGAGAATTAACA
ATGAAACTATGGATTTCAATACATCAACTAATTTGTTAACCTCCAACAAC
ATTTACACAAGCACGACACCAATAATTGCCTCGGCACAAGCCATTATGTT
GAATACGTCGACTTTGGAATGCAGAAACTTTTCTATCTTTGTGGCTGCTC
CTCCATTTATACAGTTATCGTCTGTCGTAAATACTTCTTATACCAGCCCT
GGTTACCCAACTGTGGCGAAAAATATCCCGATTGCAGGATTCTCGTTCAA
TGTCCCCTATTTCTTTTACAAAGAGAACATAACGATTATATTCACAATGT
CAGTCATTGCAGGATTGAATTTAACAAAAGGCAGAGCCCAAAGTTCCATA
ACCATTCCCGTTGTGTATTCATGTCAGACTTTGAATTGGCCCTTAAATCC
GATGGGAAATAAATATTTTAATAAAGTAGAAACGTTAGTCTTTACAGTTA
AAGGAAATGATGTCAACAACACAGTTGTTACATGCAATAATGATCTCAAC
TTGAAAGACAGTTCTGTTATACAAGATTGCGCAATAAGCGCTTACATGTC
CCCCTATCCTGGGTTTGAAGCAACAAAGATTAGAAGCAATTCTGGAAGCT
ATTGGGTACCCCACATTAGGAGTGGTCAGTATAATAAATTAAGGTACATA
GATATCAAATTCGGTAAACTCACAACTGTCACAAAAATTGTCGTGACAAG
TTCGATTGGAAATAAGCCACAAACTTTAGGAATCCATGGTACCATGGATG
GTCGAGCTTTCAGTTTCTATCAGAATATAAATATATCATATAACCCTGAC
AATACAGCCGCAGTTACATTGAACAACCCCCCCTTTACGTATCGAGGTAT
TCGAGTGTCGATTGTTGTTGCAAATCAGGATGATATAAACACCGGAATGA
ATTTAGATCTCTTTGGATGTCTGCCTCCAAATGTTACCGACACATTTACA
TTTGATCCTTGTGCAACTAAGTCATATTTAGTCCCGACAAATCCTCTCCC
TGAATTCTATTATCGAGGATACCTCTATACGAATCAACAGTTATTTGTTT
GTGATGAAATTGTCAGCCTAAGCTTTGGGTTAGAAACATATCCTAGATGT
TTCAGAACTAATACCGCTACGTTCACCACATGGGAAGATTTGGGGAATCA
AGTTGGGAAAGTAATTGGATTTGACAGTGTCAATATGATTATTTATGCCA
TTGCTTCTGATATTAAAAGCTATATAATGAGCGAAGATAACGGGTTAACG
TGGGTGGGAATTAATGGAGGAGGCTGGCAAATTATGAAAAACACCGCCAG
TTTGCAAAGTCCAATCGTGATCCCTTGGACAAATGATACGACATTCGACT
ATTTGACGACAGGGAATAATTGTACAAAGTATACCGTGGCAACATTCAAT
TTCTGCTACGACGGCATTTACAATGGAACATCTAGAATATTTTCCTGGAA
TAATTGCTGCAACTTTTAAAGATTAATGCTATAGACCTTTAACACATACT
GTTTGTCATGACCATAGAACCTTATCCAAAACATCTGTCATTCCATGAGA
ACTTTCATGGATATTATTTGTTTGTTCGATTTATCATGTAAATATTTATT
ATAAACAATATTTTGTTTTTTTGTTTGATAACTTATACTTTTTTATTATG
TGTTTACTTGGACAAATGTCCCTGCTGGTTTAGGTTGTTACTCGAAGGAG
ATTCCGAGGAGATCGAACATGTCAAGGGATTCCTAGATTTGTTACTATTT
GCTGTCATAAACATTGC
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protein sequence of SMED30000129-orf-1

>SMED30000129-orf-1 ID=SMED30000129-orf-1|Name=SMED30000129-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1830bp
MNRQIFLIFLILIFNRICYGEVCGNDDCVNGVCVNDVCVCKECFTGPTCA
LFSNKLPHFEKSSYHLVFNESKKDTTPVIKVTAIDEDKCVRGNCECGEII
YSILEENAKELFEINSSSGEIKVIQGAVIPETKYSFSVKVTNRNPFDDRY
DTATIFVNGDSSNEILERHRRATAPTKPAFELIQTFPIQNLTSINIGQRL
SMQLSVAFPVGTTTLSVELFAPESQSYPVMMICDVNVISVGSLLTTNSYN
PPLQEGINGTVWPYTHIVYNFTNVINAQSSVTSLADIQIVITFDVVMLYS
PNTTDGATYYVSGGSEYLNGTEIWVGQLGYIANLSTPTINPTISITGDTL
VYPGRTAAFVLTIQAPDSYLYLNLGIYSPLNNSVALSLCVVNRYYVGAAY
SCLPTNYNQPTLKQVTINNQIYYTSALMNLGILGNRYYMEPTHTDMNEKT
INISITARISPTLWLGTYQYIGLSISNTLTTIYTKTYQVLVSPAPQLTAY
TSPISYSLGYHKNITSVSIGSPGRININISIPTGTELDYTIIARSPENTS
EICGVIFFKAGLNIPCVDQITFGTTYVYTPDNFATTSITSIGGIRHVKIS
NNTDDDILQLVLVFRPINDSRNSVNGITNIGVKVNWTGSTGTENFLPVTL
NAPDVSSANSTTLPTFTFQLNGNDGNVSVNGNYKLFFAMRLYPGTIYTPT
SLEFYMPFNGTIRVGMCKASITYVGKNVLCFNPTFITKSFIFSSKINDTS
NYDKLLIPTGVLCTSGSSSAAPSINDEIQISINILILPHAMNTVGATANL
NGGMMISSTQIWVGNQPLTFITIPAIPSLNSSSSPLLFAQRVDSTSSNVW
INDMVIIQYIIKVAPAVVTRMTLSISTDATVATNNFGVCQVKIINQGLSI
PCVNGTLTTTPATAFSKFYVSGNFAFTDILNTGTVALVANPTFDENSLLV
EVIVKLGPTLPPSFNVIASLTSNGATASANVPLTFTSAFSRFNGTVASTE
PVFNMFLYPLFNDTNAVINNIAYSEAMRSVVSVEMKPNVLQSLKIVFAST
PNIVNQMDVISVNILSVGRNIPCLQKGMIPFSIQQRSNSLSKDLASIDMG
TICHRPYLDNTTVEDNKIYIESVFRIWKFPATSPLTLQINVLGLLNNDQV
YVTRIVFNTSTTPFVTDFSLTGESFNANATISSASVAVGGNFTVKVMVTI
PPYTQFKSGTITVGNQNPVGSDSFYFINGNANFSGTSGQNIGINKDEPMP
FTLKSTFNTSQLDNIVADLGVVQNTATTYRMNQVNYSAPTPDDTLTVTLP
VQLTDNSMASNGQIINFIVGVSFGSKTLNFSLQITVLRINNETMDFNTST
NLLTSNNIYTSTTPIIASAQAIMLNTSTLECRNFSIFVAAPPFIQLSSVV
NTSYTSPGYPTVAKNIPIAGFSFNVPYFFYKENITIIFTMSVIAGLNLTK
GRAQSSITIPVVYSCQTLNWPLNPMGNKYFNKVETLVFTVKGNDVNNTVV
TCNNDLNLKDSSVIQDCAISAYMSPYPGFEATKIRSNSGSYWVPHIRSGQ
YNKLRYIDIKFGKLTTVTKIVVTSSIGNKPQTLGIHGTMDGRAFSFYQNI
NISYNPDNTAAVTLNNPPFTYRGIRVSIVVANQDDINTGMNLDLFGCLPP
NVTDTFTFDPCATKSYLVPTNPLPEFYYRGYLYTNQQLFVCDEIVSLSFG
LETYPRCFRTNTATFTTWEDLGNQVGKVIGFDSVNMIIYAIASDIKSYIM
SEDNGLTWVGINGGGWQIMKNTASLQSPIVIPWTNDTTFDYLTTGNNCTK
YTVATFNFCYDGIYNGTSRIFSWNNCCNF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
PLANA:0000464GABAergic neuron
Vocabulary: INTERPRO
TermDefinition
IPR002126Cadherin-like_dom
IPR008979Galactose-bd-like_sf
IPR000421FA58C
IPR015919Cadherin-like_sf
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
Vocabulary: biological process
TermDefinition
GO:0007156homophilic cell adhesion via plasma membrane adhesion molecules