Leucine-rich repeat-containing protein 40

Overview
NameLeucine-rich repeat-containing protein 40
Smed IDSMED30000082
Length (bp)2000
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Leucine-rich repeat-containing protein 40 (SMED30000082) t-SNE clustered cells

Violin plots show distribution of expression levels for Leucine-rich repeat-containing protein 40 (SMED30000082) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Leucine-rich repeat-containing protein 40 (SMED30000082) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Leucine-rich repeat-containing protein 40 (SMED30000082) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30000082

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30000082h1SMcG0000960 Contig2316GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30000082h1SMcG0011571 Contig2316GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
posterior sideSMED30000082h1SMcG0011571 dd_Smed_v4_9666_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30000082h1SMcG0011571 dd_Smed_v4_9666_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Human
Match: LRRC40 (leucine rich repeat containing 40 [Source:HGNC Symbol;Acc:HGNC:26004])

HSP 1 Score: 300.442 bits (768), Expect = 1.294e-92
Identity = 207/589 (35.14%), Postives = 341/589 (57.89%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDE--KSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMR-----NTQEEEPKSFGPGLQALNRATIKD--DSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
            + LLK A+KSG LNL+ RN+SE+P  V++IN+ ++ +E  +++SF  ++  WW+   LTKLI++ N +  ++ D+ LL  L+ LDI DN ++SLP +I  L  L+  N++ NK++ LP++I N   L+ L   +N L  + +G   LSNL  +DLS+N ++  P   + L  L +L+LS N++ S+P  + R+  L+ LD + N L+T          +  ++L  N+L   P       LKE+ +  N I  +  +HL  + +I  L + +NK+  +P+EI +L SL  LDLSNND+ +LP SLG++  LK L+++GNP R ++R II+ G   + +YLR +      +Q E        L + +R  I        +D +D +AT I            DE+ +++ S  V  IN + N+    P ++ +  + + D+DLS N++S +   +  L  L  LD+  N +  LPE +  +  L    LS+N     +P+V+ R+  L+T+++S+  +  +D +K+KM+ NL  L++ NN +  IPPELG C  +++L LDGN F+VPR AI+ KGTA+++EYLR RI T
Sbjct:   29 QGLLKAARKSGQLNLSGRNLSEVPQCVWRINV-DIPEEANQNLSFGATER-WWEQTDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL-HLKFLALEGNPLRTIRREIISKGTQEVLKYLRSKIKDDGPSQSESATETAMTLPSESRVNIHAIITLKILDYSDKQATLI-----------PDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRF-KMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRVPRAAILMKGTAAILEYLRDRIPT 602          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Human
Match: LRRD1 (leucine rich repeats and death domain containing 1 [Source:HGNC Symbol;Acc:HGNC:34300])

HSP 1 Score: 125.946 bits (315), Expect = 2.381e-29
Identity = 165/595 (27.73%), Postives = 277/595 (46.55%), Query Frame = 2
Query:  164 SLNLANRNISEIPNSVYKINMPN---VNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSIT---NLTQLKYFN--------------------INKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFS---EGF----------------------CAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNL-ADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSY--NDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGN 1783
            ++NL  + + E P  + KI       ++  +  +F+ +DS   D + L  L L  N +S +  +I LL  L  L++S N+IS +P  I+   N+ QL ++N                    + KNK++ +PD + +   L+ L+  YN L + PK L  L  L  +DL+ N IS  P +I EL  L  L + +N++T +   + +L  ++ L L+ NKL+  S   E F                      CA +  + L  N+LT+ P  +    NL+++ +  N + +IT D +S + NIC+L  + N I D+P EI     +  ++LS N +   PL L  ++ L  LS++GN    +   I  S     K+ L +  ++              N+  I  +  F    +L+   + K   + + A +S+ I  SLH +      L  NKF  FP ++    ++LQ LDLS NQ+ ++ + I +L G+++L+ S N+    P  L ++  L    +S         +P  +S M  L+ L +S+  +  I    I  L NL  L+  NN IS +PP L     ++ LNL GN
Sbjct:  145 TVNLEAKGLQEFPKDILKIKYVKYLYLDKNQIKTFQGADSG--DLLGLEILSLQENGLSSLPSEIQLLHNLRILNVSHNHISHIPKEISQLGNIRQLFFYNNYIENFPSDLECLGNLEILSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTTFPKALCFLPKLISLDLTGNLISSLPKEIRELKNLETLLMDHNKLTFLAVEIFQLLKIKELQLADNKLEVISHKIENFRELRILILDKNLLKNIPEKISCCAMLECLSLSDNKLTELPKYIHKLNNLRKLHVNRNNMVKIT-DCISHLNNICSLEFSGNIITDVPIEIKNCQKIIKIELSYNKIMYFPLGLCALDSLYYLSVNGNYISEIPVDISFS-----KQLLHLELSE--------------NKLLIFSEH-FCSLINLKYLDLGKNQIKKIPASISNMI--SLHVLI-----LCCNKFETFPRELCTL-ENLQVLDLSENQLQKISSDICNLKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTRLPGELSNMTQLKELDISNNAIREIP-RNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGN 707          

HSP 2 Score: 104.76 bits (260), Expect = 1.403e-22
Identity = 92/294 (31.29%), Postives = 157/294 (53.40%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSI-INSGAD--SIKRYLRMRNTQEEE 1165
            L  L +  N IS I  DIS   +L HL++S+N +    +   +L  LKY ++ KN+I+K+P  I N + L  L    N  ++ P+ L  L NL ++DLS N++ +    I  L  + KL+ S NQ    P  L +L +L+ L++SQ K +                  +LT+ P  L N   LKE+ +++N I EI ++ + ++ N+ +L   NN+I+ +P  +  L  L  L+LS N++ ALP ++ ++  LK ++ D NP  +L+  + I  G    +I RYL+  + ++E+
Sbjct:  489 LYYLSVNGNYISEIPVDISFSKQLLHLELSENKLLIFSEHFCSLINLKYLDLGKNQIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQLQKISSDICNLKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGR------------------KLTRLPGELSNMTQLKELDISNNAIREIPRN-IGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALPSAIYNIFSLKEINFDDNP--LLRPPVEICKGKQLYTIARYLQRADERDEK 761          

HSP 3 Score: 92.8189 bits (229), Expect = 8.667e-19
Identity = 92/322 (28.57%), Postives = 157/322 (48.76%), Query Frame = 2
Query:  167 LNLANRNISEIPNSVYKIN---MPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITK--DHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIIN 1108
            L+L++  ++E+P  ++K+N     +VN    +      S   +   +  L  + N I+ +  +I    K+  +++S N I   P  +  L  L Y ++N N I ++P  I    +L  L  S N L    +    L NL  +DL  N+I + P  I+ +  L  L L  N+  + P  L  L NLQ+LDLS+N+LQ  S   C    + ++    N+   FPI L   ++L++++++     ++T+    LS +  +  L I+NN I +IP  I  L +L +L   NN +  LP SL  +  L+ L++ GN    L  +I N
Sbjct:  400 LSLSDNKLTELPKYIHKLNNLRKLHVNRNNMVKITDCISHLNN---ICSLEFSGNIITDVPIEIKNCQKIIKIELSYNKIMYFPLGLCALDSLYYLSVNGNYISEIPVDISFSKQLLHLELSENKLLIFSEHFCSLINLKYLDLGKNQIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQLQKISSDICNLKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTRLPGELSNMTQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALPSAIYN 718          

HSP 4 Score: 54.299 bits (129), Expect = 8.149e-7
Identity = 89/363 (24.52%), Postives = 165/363 (45.45%), Query Frame = 2
Query:  587 LSHNEISEFPPQINE-----LYLLT---KLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFS---EGFCAPVHQIWLHVNRLTKFP--IVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMS 1636
            LSH  + E  PQ++E     L L      ++L    +   P  + ++  ++ L L +N+++TF     G    +  + L  N L+  P  I L + NL+ ++++HN IS I K+ +S++ NI  L   NN I + P ++  L +L  L L  N ++ +P +L  ++ L+ L+++ N      +++                        F P L +L+       S   +  +L+    + +    L  L+ EI   L    +K + L  NK  +   KI  F + L+ L L  N +  +P  IS  + L  L +S NK+  LP+ + +++ L    ++ N++   I D +S +N + +L  S
Sbjct:  117 LSHETVGEVSPQVSEENQKQLGLGADNFTVNLEAKGLQEFPKDILKIKYVKYLYLDKNQIKTFQGADSGDLLGLEILSLQENGLSSLPSEIQLLH-NLRILNVSHNHISHIPKE-ISQLGNIRQLFFYNNYIENFPSDLECLGNLEILSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTTFPKAL-----------------------CFLPKLISLDLTGNLISSLPKEIRELKNLETLLMDHNKLTFLAVEIFQLL---KIKELQLADNKLEVISHKIENFRE-LRILILDKNLLKNIPEKISCCAMLECLSLSDNKLTELPKYIHKLNNLRKLHVNRNNMVK-ITDCISHLNNICSLEFS 449          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Human
Match: LRRD1 (leucine rich repeats and death domain containing 1 [Source:HGNC Symbol;Acc:HGNC:34300])

HSP 1 Score: 125.946 bits (315), Expect = 2.381e-29
Identity = 165/595 (27.73%), Postives = 277/595 (46.55%), Query Frame = 2
Query:  164 SLNLANRNISEIPNSVYKINMPN---VNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSIT---NLTQLKYFN--------------------INKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFS---EGF----------------------CAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNL-ADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSY--NDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGN 1783
            ++NL  + + E P  + KI       ++  +  +F+ +DS   D + L  L L  N +S +  +I LL  L  L++S N+IS +P  I+   N+ QL ++N                    + KNK++ +PD + +   L+ L+  YN L + PK L  L  L  +DL+ N IS  P +I EL  L  L + +N++T +   + +L  ++ L L+ NKL+  S   E F                      CA +  + L  N+LT+ P  +    NL+++ +  N + +IT D +S + NIC+L  + N I D+P EI     +  ++LS N +   PL L  ++ L  LS++GN    +   I  S     K+ L +  ++              N+  I  +  F    +L+   + K   + + A +S+ I  SLH +      L  NKF  FP ++    ++LQ LDLS NQ+ ++ + I +L G+++L+ S N+    P  L ++  L    +S         +P  +S M  L+ L +S+  +  I    I  L NL  L+  NN IS +PP L     ++ LNL GN
Sbjct:  145 TVNLEAKGLQEFPKDILKIKYVKYLYLDKNQIKTFQGADSG--DLLGLEILSLQENGLSSLPSEIQLLHNLRILNVSHNHISHIPKEISQLGNIRQLFFYNNYIENFPSDLECLGNLEILSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTTFPKALCFLPKLISLDLTGNLISSLPKEIRELKNLETLLMDHNKLTFLAVEIFQLLKIKELQLADNKLEVISHKIENFRELRILILDKNLLKNIPEKISCCAMLECLSLSDNKLTELPKYIHKLNNLRKLHVNRNNMVKIT-DCISHLNNICSLEFSGNIITDVPIEIKNCQKIIKIELSYNKIMYFPLGLCALDSLYYLSVNGNYISEIPVDISFS-----KQLLHLELSE--------------NKLLIFSEH-FCSLINLKYLDLGKNQIKKIPASISNMI--SLHVLI-----LCCNKFETFPRELCTL-ENLQVLDLSENQLQKISSDICNLKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTRLPGELSNMTQLKELDISNNAIREIP-RNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGN 707          

HSP 2 Score: 104.76 bits (260), Expect = 1.403e-22
Identity = 92/294 (31.29%), Postives = 157/294 (53.40%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSI-INSGAD--SIKRYLRMRNTQEEE 1165
            L  L +  N IS I  DIS   +L HL++S+N +    +   +L  LKY ++ KN+I+K+P  I N + L  L    N  ++ P+ L  L NL ++DLS N++ +    I  L  + KL+ S NQ    P  L +L +L+ L++SQ K +                  +LT+ P  L N   LKE+ +++N I EI ++ + ++ N+ +L   NN+I+ +P  +  L  L  L+LS N++ ALP ++ ++  LK ++ D NP  +L+  + I  G    +I RYL+  + ++E+
Sbjct:  489 LYYLSVNGNYISEIPVDISFSKQLLHLELSENKLLIFSEHFCSLINLKYLDLGKNQIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQLQKISSDICNLKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGR------------------KLTRLPGELSNMTQLKELDISNNAIREIPRN-IGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALPSAIYNIFSLKEINFDDNP--LLRPPVEICKGKQLYTIARYLQRADERDEK 761          

HSP 3 Score: 92.8189 bits (229), Expect = 8.667e-19
Identity = 92/322 (28.57%), Postives = 157/322 (48.76%), Query Frame = 2
Query:  167 LNLANRNISEIPNSVYKIN---MPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITK--DHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIIN 1108
            L+L++  ++E+P  ++K+N     +VN    +      S   +   +  L  + N I+ +  +I    K+  +++S N I   P  +  L  L Y ++N N I ++P  I    +L  L  S N L    +    L NL  +DL  N+I + P  I+ +  L  L L  N+  + P  L  L NLQ+LDLS+N+LQ  S   C    + ++    N+   FPI L   ++L++++++     ++T+    LS +  +  L I+NN I +IP  I  L +L +L   NN +  LP SL  +  L+ L++ GN    L  +I N
Sbjct:  400 LSLSDNKLTELPKYIHKLNNLRKLHVNRNNMVKITDCISHLNN---ICSLEFSGNIITDVPIEIKNCQKIIKIELSYNKIMYFPLGLCALDSLYYLSVNGNYISEIPVDISFSKQLLHLELSENKLLIFSEHFCSLINLKYLDLGKNQIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQLQKISSDICNLKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTRLPGELSNMTQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALPSAIYN 718          

HSP 4 Score: 54.299 bits (129), Expect = 8.149e-7
Identity = 89/363 (24.52%), Postives = 165/363 (45.45%), Query Frame = 2
Query:  587 LSHNEISEFPPQINE-----LYLLT---KLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFS---EGFCAPVHQIWLHVNRLTKFP--IVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMS 1636
            LSH  + E  PQ++E     L L      ++L    +   P  + ++  ++ L L +N+++TF     G    +  + L  N L+  P  I L + NL+ ++++HN IS I K+ +S++ NI  L   NN I + P ++  L +L  L L  N ++ +P +L  ++ L+ L+++ N      +++                        F P L +L+       S   +  +L+    + +    L  L+ EI   L    +K + L  NK  +   KI  F + L+ L L  N +  +P  IS  + L  L +S NK+  LP+ + +++ L    ++ N++   I D +S +N + +L  S
Sbjct:  117 LSHETVGEVSPQVSEENQKQLGLGADNFTVNLEAKGLQEFPKDILKIKYVKYLYLDKNQIKTFQGADSGDLLGLEILSLQENGLSSLPSEIQLLH-NLRILNVSHNHISHIPKE-ISQLGNIRQLFFYNNYIENFPSDLECLGNLEILSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTTFPKAL-----------------------CFLPKLISLDLTGNLISSLPKEIRELKNLETLLMDHNKLTFLAVEIFQLL---KIKELQLADNKLEVISHKIENFRE-LRILILDKNLLKNIPEKISCCAMLECLSLSDNKLTELPKYIHKLNNLRKLHVNRNNMVK-ITDCISHLNNICSLEFS 449          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Human
Match: MFHAS1 (malignant fibrous histiocytoma amplified sequence 1 [Source:HGNC Symbol;Acc:HGNC:16982])

HSP 1 Score: 112.849 bits (281), Expect = 5.214e-25
Identity = 88/308 (28.57%), Postives = 147/308 (47.73%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDK-LSHLDISDNNISSL-PDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFP------------------------IVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRY 1135
            L  L+L  N  + +   ++ L   L+ LD+S N +++L  + ++ L +L+  N++ N++  LP Q+     L+ L  S+N L  LP  L+CLS L  +D+ HN+++ FP Q+ +L  L +LD+S N++  +P  +  L  L+IL LS  +L T   GFC  A +  + L  N L   P                         +LP   L+E+ L+ N ++ +    +S +  + TL + NN+I  +P+ I  LT L  L L  N +  LP   G + ++    I  NP       +   G   I  Y
Sbjct:   89 LRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVP-SLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWKIKDNPLIQPPYEVCMKGIPYIAAY 395          

HSP 2 Score: 80.1073 bits (196), Expect = 7.205e-15
Identity = 82/319 (25.71%), Postives = 149/319 (46.71%), Query Frame = 2
Query:  701 LHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLP-----NKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEIL--NSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMN 1612
            L +++ L+L  N L+   EG  + +  + + V R  +F  + P       +L E+ ++HN ++ +  + +S +  +  L +++N++  +P ++  L  L  LD+S N +  LP SL  + +L+ L +D N      R ++   A      L   +      +     + AL    I   SG          G +   F  LA L   +L  N L ++P        +K +NL+ N F  FP  +   +  L++L LS NQ++ +P+ IS L  L  L +  N+IR LP+S+ E++ L   +L  N I   +PD   +++
Sbjct:   62 LGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVA------LEELDVSSNRLRGLPEDISALRALKILWLSG-------AELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLA-GLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIA-VLPDHFGQLS 365          

HSP 3 Score: 64.3142 bits (155), Expect = 5.473e-10
Identity = 58/228 (25.44%), Postives = 95/228 (41.67%), Query Frame = 2
Query:  290 VFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFP-IVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISI 970
            V L +L +++N +  + +DIS L  L  L +S   + +LP     L  L+   ++ N +Q LP Q                        +CL  L +++LS N   EFP  +  L  L +L LS NQ+TS+P  +  L  L  L                     WL  NR+   P  ++    L+E+ L  N I+ +  DH  ++  +    I +N +   P E+ +
Sbjct:  204 VALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQ-----------------------FSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTL---------------------WLDNNRIRYLPDSIVELTGLEELVLQGNQIA-VLPDHFGQLSRVGLWKIKDNPLIQPPYEVCM 386          

HSP 4 Score: 52.7582 bits (125), Expect = 2.572e-6
Identity = 44/153 (28.76%), Postives = 81/153 (52.94%), Query Frame = 2
Query: 1343 INLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCE--KIKSLNLDGNCFKV 1795
            ++++ N+ +    ++      L+ L+LS+NQ+  LP  + +L+ L  LD+SFN++  LP+SLS +S L    + +N +    P  + ++  L+ L +S   L  +  E I  L  L++L +S   +  +P   G CE   ++SL LD N  + 
Sbjct:  116 LDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQL-TAFPRQLLQLVALEELDVSSNRLRGLP-EDISALRALKILWLSGAELGTLP--AGFCELASLESLMLDNNGLQA 264          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Human
Match: MFHAS1 (malignant fibrous histiocytoma amplified sequence 1 [Source:HGNC Symbol;Acc:HGNC:16982])

HSP 1 Score: 112.464 bits (280), Expect = 5.446e-25
Identity = 88/308 (28.57%), Postives = 147/308 (47.73%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDK-LSHLDISDNNISSL-PDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFP------------------------IVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRY 1135
            L  L+L  N  + +   ++ L   L+ LD+S N +++L  + ++ L +L+  N++ N++  LP Q+     L+ L  S+N L  LP  L+CLS L  +D+ HN+++ FP Q+ +L  L +LD+S N++  +P  +  L  L+IL LS  +L T   GFC  A +  + L  N L   P                         +LP   L+E+ L+ N ++ +    +S +  + TL + NN+I  +P+ I  LT L  L L  N +  LP   G + ++    I  NP       +   G   I  Y
Sbjct:   89 LRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVP-SLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWKIKDNPLIQPPYEVCMKGIPYIAAY 395          

HSP 2 Score: 80.1073 bits (196), Expect = 9.010e-15
Identity = 82/319 (25.71%), Postives = 149/319 (46.71%), Query Frame = 2
Query:  701 LHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLP-----NKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEIL--NSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMN 1612
            L +++ L+L  N L+   EG  + +  + + V R  +F  + P       +L E+ ++HN ++ +  + +S +  +  L +++N++  +P ++  L  L  LD+S N +  LP SL  + +L+ L +D N      R ++   A      L   +      +     + AL    I   SG          G +   F  LA L   +L  N L ++P        +K +NL+ N F  FP  +   +  L++L LS NQ++ +P+ IS L  L  L +  N+IR LP+S+ E++ L   +L  N I   +PD   +++
Sbjct:   62 LGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVA------LEELDVSSNRLRGLPEDISALRALKILWLSG-------AELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLA-GLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIA-VLPDHFGQLS 365          

HSP 3 Score: 64.3142 bits (155), Expect = 5.861e-10
Identity = 58/228 (25.44%), Postives = 95/228 (41.67%), Query Frame = 2
Query:  290 VFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFP-IVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISI 970
            V L +L +++N +  + +DIS L  L  L +S   + +LP     L  L+   ++ N +Q LP Q                        +CL  L +++LS N   EFP  +  L  L +L LS NQ+TS+P  +  L  L  L                     WL  NR+   P  ++    L+E+ L  N I+ +  DH  ++  +    I +N +   P E+ +
Sbjct:  204 VALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQ-----------------------FSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTL---------------------WLDNNRIRYLPDSIVELTGLEELVLQGNQIA-VLPDHFGQLSRVGLWKIKDNPLIQPPYEVCM 386          

HSP 4 Score: 52.373 bits (124), Expect = 2.801e-6
Identity = 44/153 (28.76%), Postives = 81/153 (52.94%), Query Frame = 2
Query: 1343 INLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCE--KIKSLNLDGNCFKV 1795
            ++++ N+ +    ++      L+ L+LS+NQ+  LP  + +L+ L  LD+SFN++  LP+SLS +S L    + +N +    P  + ++  L+ L +S   L  +  E I  L  L++L +S   +  +P   G CE   ++SL LD N  + 
Sbjct:  116 LDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQL-TAFPRQLLQLVALEELDVSSNRLRGLP-EDISALRALKILWLSGAELGTLP--AGFCELASLESLMLDNNGLQA 264          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Celegans
Match: soc-2 (Leucine-rich repeat protein soc-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22875])

HSP 1 Score: 118.627 bits (296), Expect = 7.179e-28
Identity = 139/511 (27.20%), Postives = 246/511 (48.14%), Query Frame = 2
Query:  371 HLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPG--LQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPP-ELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLR 1849
             LD+S   I+S+P  I  LTQL    + KNK+  LP +I   + L+ L  S N L SLP  L  L +L  +DL HN+++E P  I ++  L  L L YN+I ++   +  L  L++LD+ +NK++      G    +    +  N LT+ P  + +  +L ++ L HN +SE+    + K+ N+  + I  NKI  IP E                       L   +QL+   ++ N  ++L  +++     ++   +   N    E  +F  G   Q ++  TI  +   I +  +    +AT + KL+ +          N L S+P        +  +NL+ N+  + P  I +  + L+ L LSNNQ+ +LPN I +L+ LR LD+  N++  +P  +  +  L+   +  N I  T+P  +  +  LQ L +    LT I  E+I  L +L+ L +++N+  +  P EL LC+ ++ ++++ +      P I + G + V++YL+
Sbjct:   67 RLDLSSIEITSIPSPIKELTQLTELFLYKNKLTCLPTEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKLTEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCHSLTQLDLQHNDLSELPYS-IGKLVNLVRIGIRYNKIRCIPSE-----------------------LESCQQLEEFIVESNHLQLLPPNLL-----TMLPKIHTVNLSRNELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKE---------NELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVN-LEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKIL-TLPRSIGNLCSLQDLRLGENNLTAIP-EEIGHLDSLKSLYLNDNSSLHNLPFELALCQSLEIMSIENSPLSQIPPEITAGGPSLVIQYLK 536          

HSP 2 Score: 98.5969 bits (244), Expect = 2.748e-21
Identity = 101/401 (25.19%), Postives = 170/401 (42.39%), Query Frame = 2
Query:   74 DNSLFIDIGNSESQNNKAFENLLKQAKKSGS-----LNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDS----------------------------------------------ITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA---PVHQIWLHVNRLTKFPIVLPNKNLKEIS--LTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIIN 1108
            D + F+   N  +    A ++LLK+  K        L+L++  I+ IP+ + ++                         LT+L L  N ++ +  +I  L  L  L +S+N ++SLPDS                                              I NL++LK  ++ +NKI++LP  I     L     SYN L  +P+ +    +LT +DL HN++SE P  I +L  L ++ + YN+I  +P  LE    L+   +  N LQ            +H + L  N LT FP   P + +  ++  + HN IS+I     SK   +  L +  N++  +P ++   TS++ L+LS N +K LP  +  +  L+ L +  N  + L   I N
Sbjct:   32 DRAYFLRQKNMRNNKGHAEKDLLKEFHKCKEAQDQRLDLSSIEITSIPSPIKELTQ-----------------------LTELFLYKNKLTCLPTEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKLTEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCHSLTQLDLQHNDLSELPYSIGKLVNLVRIGIRYNKIRCIPSELESCQQLEEFIVESNHLQLLPPNLLTMLPKIHTVNLSRNELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGN 409          

HSP 3 Score: 58.9214 bits (141), Expect = 8.516e-9
Identity = 51/147 (34.69%), Postives = 81/147 (55.10%), Query Frame = 2
Query:  320 NSISFISKDI-SLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE 757
            N IS I   I S   +L+ L++ +N + SLP  + + T +   N++ N+++ LP+ IE  + L+ L  S N LK LP  +  L+ L  +DL  NE+   P +I  L  LTKL +  N+I ++P ++  L +LQ L L +N L    E
Sbjct:  328 NQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPE 474          

HSP 4 Score: 55.8398 bits (133), Expect = 7.860e-8
Identity = 46/147 (31.29%), Postives = 79/147 (53.74%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQN 736
            LTKL L  N +  +  D+     ++ L++S N +  LP+ I  L  L+   ++ N+++KLP+QI N  +L+ L    N L+++P  +  L +LT + +  N+I   P  I  L  L  L L  N +T++P  +  L +L+ L L+ N
Sbjct:  344 LTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPEEIGHLDSLKSLYLNDN 490          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Celegans
Match: soc-2 (Leucine-rich repeat protein soc-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22875])

HSP 1 Score: 118.627 bits (296), Expect = 7.441e-28
Identity = 139/511 (27.20%), Postives = 246/511 (48.14%), Query Frame = 2
Query:  371 HLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPG--LQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPP-ELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLR 1849
             LD+S   I+S+P  I  LTQL    + KNK+  LP +I   + L+ L  S N L SLP  L  L +L  +DL HN+++E P  I ++  L  L L YN+I ++   +  L  L++LD+ +NK++      G    +    +  N LT+ P  + +  +L ++ L HN +SE+    + K+ N+  + I  NKI  IP E                       L   +QL+   ++ N  ++L  +++     ++   +   N    E  +F  G   Q ++  TI  +   I +  +    +AT + KL+ +          N L S+P        +  +NL+ N+  + P  I +  + L+ L LSNNQ+ +LPN I +L+ LR LD+  N++  +P  +  +  L+   +  N I  T+P  +  +  LQ L +    LT I  E+I  L +L+ L +++N+  +  P EL LC+ ++ ++++ +      P I + G + V++YL+
Sbjct:   76 RLDLSSIEITSIPSPIKELTQLTELFLYKNKLTCLPTEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKLTEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCHSLTQLDLQHNDLSELPYS-IGKLVNLVRIGIRYNKIRCIPSE-----------------------LESCQQLEEFIVESNHLQLLPPNLL-----TMLPKIHTVNLSRNELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKE---------NELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVN-LEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKIL-TLPRSIGNLCSLQDLRLGENNLTAIP-EEIGHLDSLKSLYLNDNSSLHNLPFELALCQSLEIMSIENSPLSQIPPEITAGGPSLVIQYLK 545          

HSP 2 Score: 98.5969 bits (244), Expect = 2.349e-21
Identity = 101/401 (25.19%), Postives = 170/401 (42.39%), Query Frame = 2
Query:   74 DNSLFIDIGNSESQNNKAFENLLKQAKKSGS-----LNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDS----------------------------------------------ITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA---PVHQIWLHVNRLTKFPIVLPNKNLKEIS--LTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIIN 1108
            D + F+   N  +    A ++LLK+  K        L+L++  I+ IP+ + ++                         LT+L L  N ++ +  +I  L  L  L +S+N ++SLPDS                                              I NL++LK  ++ +NKI++LP  I     L     SYN L  +P+ +    +LT +DL HN++SE P  I +L  L ++ + YN+I  +P  LE    L+   +  N LQ            +H + L  N LT FP   P + +  ++  + HN IS+I     SK   +  L +  N++  +P ++   TS++ L+LS N +K LP  +  +  L+ L +  N  + L   I N
Sbjct:   41 DRAYFLRQKNMRNNKGHAEKDLLKEFHKCKEAQDQRLDLSSIEITSIPSPIKELTQ-----------------------LTELFLYKNKLTCLPTEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKLTEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCHSLTQLDLQHNDLSELPYSIGKLVNLVRIGIRYNKIRCIPSELESCQQLEEFIVESNHLQLLPPNLLTMLPKIHTVNLSRNELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGN 418          

HSP 3 Score: 58.9214 bits (141), Expect = 8.178e-9
Identity = 51/147 (34.69%), Postives = 81/147 (55.10%), Query Frame = 2
Query:  320 NSISFISKDI-SLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE 757
            N IS I   I S   +L+ L++ +N + SLP  + + T +   N++ N+++ LP+ IE  + L+ L  S N LK LP  +  L+ L  +DL  NE+   P +I  L  LTKL +  N+I ++P ++  L +LQ L L +N L    E
Sbjct:  337 NQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPE 483          

HSP 4 Score: 55.8398 bits (133), Expect = 7.285e-8
Identity = 46/147 (31.29%), Postives = 79/147 (53.74%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQN 736
            LTKL L  N +  +  D+     ++ L++S N +  LP+ I  L  L+   ++ N+++KLP+QI N  +L+ L    N L+++P  +  L +LT + +  N+I   P  I  L  L  L L  N +T++P  +  L +L+ L L+ N
Sbjct:  353 LTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPEEIGHLDSLKSLYLNDN 499          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Celegans
Match: soc-2 (Leucine-rich repeat protein soc-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22875])

HSP 1 Score: 118.242 bits (295), Expect = 1.167e-27
Identity = 139/511 (27.20%), Postives = 246/511 (48.14%), Query Frame = 2
Query:  371 HLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPG--LQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPP-ELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLR 1849
             LD+S   I+S+P  I  LTQL    + KNK+  LP +I   + L+ L  S N L SLP  L  L +L  +DL HN+++E P  I ++  L  L L YN+I ++   +  L  L++LD+ +NK++      G    +    +  N LT+ P  + +  +L ++ L HN +SE+    + K+ N+  + I  NKI  IP E                       L   +QL+   ++ N  ++L  +++     ++   +   N    E  +F  G   Q ++  TI  +   I +  +    +AT + KL+ +          N L S+P        +  +NL+ N+  + P  I +  + L+ L LSNNQ+ +LPN I +L+ LR LD+  N++  +P  +  +  L+   +  N I  T+P  +  +  LQ L +    LT I  E+I  L +L+ L +++N+  +  P EL LC+ ++ ++++ +      P I + G + V++YL+
Sbjct:   77 RLDLSSIEITSIPSPIKELTQLTELFLYKNKLTCLPTEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKLTEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCHSLTQLDLQHNDLSELPYS-IGKLVNLVRIGIRYNKIRCIPSE-----------------------LESCQQLEEFIVESNHLQLLPPNLL-----TMLPKIHTVNLSRNELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKE---------NELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVN-LEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKIL-TLPRSIGNLCSLQDLRLGENNLTAIP-EEIGHLDSLKSLYLNDNSSLHNLPFELALCQSLEIMSIENSPLSQIPPEITAGGPSLVIQYLK 546          

HSP 2 Score: 97.8265 bits (242), Expect = 4.347e-21
Identity = 88/322 (27.33%), Postives = 143/322 (44.41%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDS----------------------------------------------ITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA---PVHQIWLHVNRLTKFPIVLPNKNLKEIS--LTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIIN 1108
            LT+L L  N ++ +  +I  L  L  L +S+N ++SLPDS                                              I NL++LK  ++ +NKI++LP  I     L     SYN L  +P+ +    +LT +DL HN++SE P  I +L  L ++ + YN+I  +P  LE    L+   +  N LQ            +H + L  N LT FP   P + +  ++  + HN IS+I     SK   +  L +  N++  +P ++   TS++ L+LS N +K LP  +  +  L+ L +  N  + L   I N
Sbjct:   98 LTELFLYKNKLTCLPTEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKLTEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCHSLTQLDLQHNDLSELPYSIGKLVNLVRIGIRYNKIRCIPSELESCQQLEEFIVESNHLQLLPPNLLTMLPKIHTVNLSRNELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGN 419          

HSP 3 Score: 58.5362 bits (140), Expect = 9.651e-9
Identity = 51/147 (34.69%), Postives = 81/147 (55.10%), Query Frame = 2
Query:  320 NSISFISKDI-SLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE 757
            N IS I   I S   +L+ L++ +N + SLP  + + T +   N++ N+++ LP+ IE  + L+ L  S N LK LP  +  L+ L  +DL  NE+   P +I  L  LTKL +  N+I ++P ++  L +LQ L L +N L    E
Sbjct:  338 NQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPE 484          

HSP 4 Score: 55.8398 bits (133), Expect = 8.519e-8
Identity = 46/147 (31.29%), Postives = 79/147 (53.74%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQN 736
            LTKL L  N +  +  D+     ++ L++S N +  LP+ I  L  L+   ++ N+++KLP+QI N  +L+ L    N L+++P  +  L +LT + +  N+I   P  I  L  L  L L  N +T++P  +  L +L+ L L+ N
Sbjct:  354 LTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPEEIGHLDSLKSLYLNDN 500          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Celegans
Match: soc-2 (Leucine-rich repeat protein soc-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22875])

HSP 1 Score: 118.242 bits (295), Expect = 1.167e-27
Identity = 139/511 (27.20%), Postives = 246/511 (48.14%), Query Frame = 2
Query:  371 HLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPG--LQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPP-ELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLR 1849
             LD+S   I+S+P  I  LTQL    + KNK+  LP +I   + L+ L  S N L SLP  L  L +L  +DL HN+++E P  I ++  L  L L YN+I ++   +  L  L++LD+ +NK++      G    +    +  N LT+ P  + +  +L ++ L HN +SE+    + K+ N+  + I  NKI  IP E                       L   +QL+   ++ N  ++L  +++     ++   +   N    E  +F  G   Q ++  TI  +   I +  +    +AT + KL+ +          N L S+P        +  +NL+ N+  + P  I +  + L+ L LSNNQ+ +LPN I +L+ LR LD+  N++  +P  +  +  L+   +  N I  T+P  +  +  LQ L +    LT I  E+I  L +L+ L +++N+  +  P EL LC+ ++ ++++ +      P I + G + V++YL+
Sbjct:   77 RLDLSSIEITSIPSPIKELTQLTELFLYKNKLTCLPTEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKLTEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCHSLTQLDLQHNDLSELPYS-IGKLVNLVRIGIRYNKIRCIPSE-----------------------LESCQQLEEFIVESNHLQLLPPNLL-----TMLPKIHTVNLSRNELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKE---------NELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVN-LEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKIL-TLPRSIGNLCSLQDLRLGENNLTAIP-EEIGHLDSLKSLYLNDNSSLHNLPFELALCQSLEIMSIENSPLSQIPPEITAGGPSLVIQYLK 546          

HSP 2 Score: 97.8265 bits (242), Expect = 4.347e-21
Identity = 88/322 (27.33%), Postives = 143/322 (44.41%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDS----------------------------------------------ITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA---PVHQIWLHVNRLTKFPIVLPNKNLKEIS--LTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIIN 1108
            LT+L L  N ++ +  +I  L  L  L +S+N ++SLPDS                                              I NL++LK  ++ +NKI++LP  I     L     SYN L  +P+ +    +LT +DL HN++SE P  I +L  L ++ + YN+I  +P  LE    L+   +  N LQ            +H + L  N LT FP   P + +  ++  + HN IS+I     SK   +  L +  N++  +P ++   TS++ L+LS N +K LP  +  +  L+ L +  N  + L   I N
Sbjct:   98 LTELFLYKNKLTCLPTEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKLTEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCHSLTQLDLQHNDLSELPYSIGKLVNLVRIGIRYNKIRCIPSELESCQQLEEFIVESNHLQLLPPNLLTMLPKIHTVNLSRNELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGN 419          

HSP 3 Score: 58.5362 bits (140), Expect = 9.651e-9
Identity = 51/147 (34.69%), Postives = 81/147 (55.10%), Query Frame = 2
Query:  320 NSISFISKDI-SLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE 757
            N IS I   I S   +L+ L++ +N + SLP  + + T +   N++ N+++ LP+ IE  + L+ L  S N LK LP  +  L+ L  +DL  NE+   P +I  L  LTKL +  N+I ++P ++  L +LQ L L +N L    E
Sbjct:  338 NQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPE 484          

HSP 4 Score: 55.8398 bits (133), Expect = 8.519e-8
Identity = 46/147 (31.29%), Postives = 79/147 (53.74%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQN 736
            LTKL L  N +  +  D+     ++ L++S N +  LP+ I  L  L+   ++ N+++KLP+QI N  +L+ L    N L+++P  +  L +LT + +  N+I   P  I  L  L  L L  N +T++P  +  L +L+ L L+ N
Sbjct:  354 LTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPEEIGHLDSLKSLYLNDN 500          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Celegans
Match: soc-2 (Leucine-rich repeat protein soc-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22875])

HSP 1 Score: 117.857 bits (294), Expect = 1.989e-27
Identity = 139/511 (27.20%), Postives = 246/511 (48.14%), Query Frame = 2
Query:  371 HLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPG--LQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPP-ELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLR 1849
             LD+S   I+S+P  I  LTQL    + KNK+  LP +I   + L+ L  S N L SLP  L  L +L  +DL HN+++E P  I ++  L  L L YN+I ++   +  L  L++LD+ +NK++      G    +    +  N LT+ P  + +  +L ++ L HN +SE+    + K+ N+  + I  NKI  IP E                       L   +QL+   ++ N  ++L  +++     ++   +   N    E  +F  G   Q ++  TI  +   I +  +    +AT + KL+ +          N L S+P        +  +NL+ N+  + P  I +  + L+ L LSNNQ+ +LPN I +L+ LR LD+  N++  +P  +  +  L+   +  N I  T+P  +  +  LQ L +    LT I  E+I  L +L+ L +++N+  +  P EL LC+ ++ ++++ +      P I + G + V++YL+
Sbjct:  149 RLDLSSIEITSIPSPIKELTQLTELFLYKNKLTCLPTEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKLTEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCHSLTQLDLQHNDLSELPYS-IGKLVNLVRIGIRYNKIRCIPSE-----------------------LESCQQLEEFIVESNHLQLLPPNLL-----TMLPKIHTVNLSRNELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKE---------NELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVN-LEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKIL-TLPRSIGNLCSLQDLRLGENNLTAIP-EEIGHLDSLKSLYLNDNSSLHNLPFELALCQSLEIMSIENSPLSQIPPEITAGGPSLVIQYLK 618          

HSP 2 Score: 98.9821 bits (245), Expect = 2.244e-21
Identity = 101/401 (25.19%), Postives = 170/401 (42.39%), Query Frame = 2
Query:   74 DNSLFIDIGNSESQNNKAFENLLKQAKKSGS-----LNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDS----------------------------------------------ITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA---PVHQIWLHVNRLTKFPIVLPNKNLKEIS--LTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIIN 1108
            D + F+   N  +    A ++LLK+  K        L+L++  I+ IP+ + ++                         LT+L L  N ++ +  +I  L  L  L +S+N ++SLPDS                                              I NL++LK  ++ +NKI++LP  I     L     SYN L  +P+ +    +LT +DL HN++SE P  I +L  L ++ + YN+I  +P  LE    L+   +  N LQ            +H + L  N LT FP   P + +  ++  + HN IS+I     SK   +  L +  N++  +P ++   TS++ L+LS N +K LP  +  +  L+ L +  N  + L   I N
Sbjct:  114 DRAYFLRQKNMRNNKGHAEKDLLKEFHKCKEAQDQRLDLSSIEITSIPSPIKELTQ-----------------------LTELFLYKNKLTCLPTEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKLTEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCHSLTQLDLQHNDLSELPYSIGKLVNLVRIGIRYNKIRCIPSELESCQQLEEFIVESNHLQLLPPNLLTMLPKIHTVNLSRNELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGN 491          

HSP 3 Score: 59.3066 bits (142), Expect = 6.206e-9
Identity = 51/147 (34.69%), Postives = 81/147 (55.10%), Query Frame = 2
Query:  320 NSISFISKDI-SLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE 757
            N IS I   I S   +L+ L++ +N + SLP  + + T +   N++ N+++ LP+ IE  + L+ L  S N LK LP  +  L+ L  +DL  NE+   P +I  L  LTKL +  N+I ++P ++  L +LQ L L +N L    E
Sbjct:  410 NQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPE 556          

HSP 4 Score: 56.225 bits (134), Expect = 5.780e-8
Identity = 46/147 (31.29%), Postives = 79/147 (53.74%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQN 736
            LTKL L  N +  +  D+     ++ L++S N +  LP+ I  L  L+   ++ N+++KLP+QI N  +L+ L    N L+++P  +  L +LT + +  N+I   P  I  L  L  L L  N +T++P  +  L +L+ L L+ N
Sbjct:  426 LTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPEEIGHLDSLKSLYLNDN 572          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Fly
Match: f-cup (gene:FBgn0028487 transcript:FBtr0082847)

HSP 1 Score: 229.18 bits (583), Expect = 8.110e-66
Identity = 181/596 (30.37%), Postives = 301/596 (50.50%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQ----SDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFG-------PGLQALNRATIKDDSG-----FIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
            + L K A+KSG+LNL+N+ ++ +P  +Y IN  +  D K+++ EQ     + +WW+ V L  L L++N+++ IS  I  L  L+ L + DN +  LP  I  L +L   N++ NK+ +LP  + +  EL+ L+ SYN    L   ++ L  L  +D  HN I   P  I  L  LT L L YN I  +P  L  + +LQ +DL  N L +  E  G    +  ++L  N + + P    N+ L E+  ++N I  I K   S +P++  L + +NKI ++P+E+ +L +L+ LD+SNN +  LP++L  +  L  L ++GNP + ++R I+  G   I + L  R   + + +  G        G+        + D G     F D+  LR T  + ++   L  + D++        V  ++   N+ S  P  +    D + +L LSNN I  +P  IS  + +  L++S N +  LP     ++ L    ++ N     IP+ V  +  L+ L+ S   + +++   ++ +  L  L++ NN I  +PP LG    I  L L GN F+ PR  I+ KGT ++M YLR RI T
Sbjct:   57 QELWKLARKSGTLNLSNKALARVPKRLYDINEADA-DSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQCGTTRILKTLHDRAVAKAKEEGGGVDDASTSAGISVTRLRGGQMDDGDIPGNFPDRYKLRHTRTLAVNLEELTSVPDQVFQIARDEGVHVVDFARNQLSTLPNGLQHMKDLVTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFP-CIPNCVYELQGLEILIASENHIKMLNVSGLQNMRRLSTLDLRNNDIETVPPILGNLTNITHLELVGNPFRQPRHQILMKGTDAIMSYLRDRIPT 650          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Fly
Match: f-cup (gene:FBgn0028487 transcript:FBtr0082846)

HSP 1 Score: 228.794 bits (582), Expect = 2.337e-65
Identity = 181/596 (30.37%), Postives = 301/596 (50.50%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQ----SDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFG-------PGLQALNRATIKDDSG-----FIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
            + L K A+KSG+LNL+N+ ++ +P  +Y IN  +  D K+++ EQ     + +WW+ V L  L L++N+++ IS  I  L  L+ L + DN +  LP  I  L +L   N++ NK+ +LP  + +  EL+ L+ SYN    L   ++ L  L  +D  HN I   P  I  L  LT L L YN I  +P  L  + +LQ +DL  N L +  E  G    +  ++L  N + + P    N+ L E+  ++N I  I K   S +P++  L + +NKI ++P+E+ +L +L+ LD+SNN +  LP++L  +  L  L ++GNP + ++R I+  G   I + L  R   + + +  G        G+        + D G     F D+  LR T  + ++   L  + D++        V  ++   N+ S  P  +    D + +L LSNN I  +P  IS  + +  L++S N +  LP     ++ L    ++ N     IP+ V  +  L+ L+ S   + +++   ++ +  L  L++ NN I  +PP LG    I  L L GN F+ PR  I+ KGT ++M YLR RI T
Sbjct:  100 QELWKLARKSGTLNLSNKALARVPKRLYDINEADA-DSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQCGTTRILKTLHDRAVAKAKEEGGGVDDASTSAGISVTRLRGGQMDDGDIPGNFPDRYKLRHTRTLAVNLEELTSVPDQVFQIARDEGVHVVDFARNQLSTLPNGLQHMKDLVTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFP-CIPNCVYELQGLEILIASENHIKMLNVSGLQNMRRLSTLDLRNNDIETVPPILGNLTNITHLELVGNPFRQPRHQILMKGTDAIMSYLRDRIPT 693          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Fly
Match: f-cup (gene:FBgn0028487 transcript:FBtr0112939)

HSP 1 Score: 208.379 bits (529), Expect = 1.996e-58
Identity = 171/575 (29.74%), Postives = 285/575 (49.57%), Query Frame = 2
Query:  194 EIPNSVYKINMPNVNDEKSISFEQ----SDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFG-------PGLQALNRATIKDDSG-----FIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
            ++P  +Y IN  +  D K+++ EQ     + +WW+ V L  L L++N+++ IS  I  L  L+ L + DN +  LP  I  L +L   N++ NK+ +LP  + +  EL+ L+ SYN    L   ++ L  L  +D  HN I   P  I  L  LT L L YN I  +P  L  + +LQ +DL  N L +  E  G    +  ++L  N + + P    N+ L E+  ++N I  I K   S +P++  L + +NKI ++P+E+ +L +L+ LD+SNN +  LP++L  +  L  L ++GNP + ++R I+  G   I + L  R   + + +  G        G+        + D G     F D+  LR T  + ++   L  + D++        V  ++   N+ S  P  +    D + +L LSNN I  +P  IS  + +  L++S N +  LP     ++ L    ++ N     IP+ V  +  L+ L+ S   + +++   ++ +  L  L++ NN I  +PP LG    I  L L GN F+ PR  I+ KGT ++M YLR RI T
Sbjct:   48 DLPKRLYDINEADA-DSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQCGTTRILKTLHDRAVAKAKEEGGGVDDASTSAGISVTRLRGGQMDDGDIPGNFPDRYKLRHTRTLAVNLEELTSVPDQVFQIARDEGVHVVDFARNQLSTLPNGLQHMKDLVTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFP-CIPNCVYELQGLEILIASENHIKMLNVSGLQNMRRLSTLDLRNNDIETVPPILGNLTNITHLELVGNPFRQPRHQILMKGTDAIMSYLRDRIPT 620          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Fly
Match: f-cup (gene:FBgn0028487 transcript:FBtr0334528)

HSP 1 Score: 166.007 bits (419), Expect = 1.099e-43
Identity = 116/356 (32.58%), Postives = 193/356 (54.21%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQ----SDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFG 1180
            + L K A+KSG+LNL+N+ ++ +P  +Y IN  +  D K+++ EQ     + +WW+ V L  L L++N+++ IS  I  L  L+ L + DN +  LP  I  L +L   N++ NK+ +LP  + +  EL+ L+ SYN    L   ++ L  L  +D  HN I   P  I  L  LT L L YN I  +P  L  + +LQ +DL  N L +  E  G    +  ++L  N + + P    N+ L E+  ++N I  I K   S +P++  L + +NKI ++P+E+ +L +L+ LD+SNN +  LP++L  +  L  L ++GNP + ++R I+  G   I + L  R   + + +  G
Sbjct:   57 QELWKLARKSGTLNLSNKALARVPKRLYDINEADA-DSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQCGTTRILKTLHDRAVAKAKEEGGG 411          

HSP 2 Score: 51.2174 bits (121), Expect = 2.618e-6
Identity = 94/344 (27.33%), Postives = 155/344 (45.06%), Query Frame = 2
Query:  641 LTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADL----SDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTII 1657
            L  LDLS N +T +   +E L +L +L L                     H N L + P  +   + L  ++++HN +S++ +   S +P +  L I+ N+  ++  +IS L  L  LD  +N++++LP  +G + +L  L +  N  + L   ++N           MR+ Q+ +       L   +  ++ +D G      LR    + L   ++ +L     +E LN LH+        + N   I P  +      L+ LDL +N+I+ELP+ +  L  L RLD+S N I VLP +LS    L+H I S    GN I  +  R + LQ      CG T I
Sbjct:  115 LNNLDLSSNTLTHISPKIENLQSLTVLTL---------------------HDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYS-LPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVN-----------MRSLQKID-------LMHNDLTSLPEDMGL-----LRKLDCLYLQHNDILELPEFEGNEALNELHA--------SNNFIKIIPKAMCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSS---LAHLI-SLQVEGNPIKTI--RRDILQ------CGTTRI 393          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Fly
Match: f-cup (gene:FBgn0028487 transcript:FBtr0334527)

HSP 1 Score: 167.162 bits (422), Expect = 2.885e-43
Identity = 116/356 (32.58%), Postives = 193/356 (54.21%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQ----SDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFG 1180
            + L K A+KSG+LNL+N+ ++ +P  +Y IN  +  D K+++ EQ     + +WW+ V L  L L++N+++ IS  I  L  L+ L + DN +  LP  I  L +L   N++ NK+ +LP  + +  EL+ L+ SYN    L   ++ L  L  +D  HN I   P  I  L  LT L L YN I  +P  L  + +LQ +DL  N L +  E  G    +  ++L  N + + P    N+ L E+  ++N I  I K   S +P++  L + +NKI ++P+E+ +L +L+ LD+SNN +  LP++L  +  L  L ++GNP + ++R I+  G   I + L  R   + + +  G
Sbjct:   57 QELWKLARKSGTLNLSNKALARVPKRLYDINEADA-DSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQCGTTRILKTLHDRAVAKAKEEGGG 411          

HSP 2 Score: 72.0182 bits (175), Expect = 1.144e-12
Identity = 60/206 (29.13%), Postives = 100/206 (48.54%), Query Frame = 2
Query: 1247 LRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
            LR T  + ++   L  + D++        V  ++   N+ S  P  +    D + +L LSNN I  +P  IS  + +  L++S N +  LP     ++ L    ++ N     IP+ V  +  L+ L+ S   + +++   ++ +  L  L++ NN I  +PP LG    I  L L GN F+ PR  I+ KGT ++M YLR RI T
Sbjct:  555 LRHTRTLAVNLEELTSVPDQVFQIARDEGVHVVDFARNQLSTLPNGLQHMKDLVTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFP-CIPNCVYELQGLEILIASENHIKMLNVSGLQNMRRLSTLDLRNNDIETVPPILGNLTNITHLELVGNPFRQPRHQILMKGTDAIMSYLRDRIPT 759          

HSP 3 Score: 51.6026 bits (122), Expect = 2.444e-6
Identity = 94/343 (27.41%), Postives = 154/343 (44.90%), Query Frame = 2
Query:  641 LTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADL----SDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTII 1657
            L  LDLS N +T +   +E L +L +L L  N L                 + +L K         L  ++++HN +S++ +   S +P +  L I+ N+  ++  +IS L  L  LD  +N++++LP  +G + +L  L +  N  + L   ++N           MR+ Q+ +       L   +  ++ +D G      LR    + L   ++ +L     +E LN LH+        + N   I P  +      L+ LDL +N+I+ELP+ +  L  L RLD+S N I VLP +L   S L+H I S    GN I  +  R + LQ      CG T I
Sbjct:  115 LNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPP-----------EIGKLEK---------LVRLNVSHNKLSQLPRAMYS-LPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVN-----------MRSLQKID-------LMHNDLTSLPEDMGL-----LRKLDCLYLQHNDILELPEFEGNEALNELHA--------SNNFIKIIPKAMCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTL---SSLAHLI-SLQVEGNPIKTI--RRDILQ------CGTTRI 393          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Zebrafish
Match: lrrc40 (leucine rich repeat containing 40 [Source:NCBI gene;Acc:334130])

HSP 1 Score: 314.694 bits (805), Expect = 3.364e-98
Identity = 205/586 (34.98%), Postives = 335/586 (57.17%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKS-ISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQ------EEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             LLK A+KSG LNL+ R ++E+P SV+++N+    + K  +SF   D  WW+   LTKL+L++N +  I  D+ LL  L  LDI DN +SSLPDSI +L QL+   ++ NK+ +LP  +     L+ L    N ++ +P+ L  L NL  +DLS+N + + P  +  L  L KLDLS N++ S+P  + ++ NL++LD S+N++++          + Q++L  N+L   P +   K LKE+   +N I  +  +HL  +  +  L + +NK+  +PEEI++L  L  LDL+NND+ +LP  LG + +LK LS++GNP R ++R ++  G   + +YLR R  +      +EEPK+          A        I+   ++    +  S +  A + D++ +++   PV  +N + N+ +  P +I    D+L D++L  N+++ +P     L  L  +D+  N +  LP  L  +  L   ILS+N    + P+V+ R+  L+T+++S   +  ID  ++K LS L  L++SNN I  +PPELG C  +++L LDGN F+ PR AI+ KGT +V+EYLRSRI T
Sbjct:   28 GLLKAARKSGQLNLSGRGLTEVPASVWRLNLDTPQEAKQNVSFGAEDR-WWEQTDLTKLLLSSNKLQSIPDDVKLLPALVVLDIHDNQLSSLPDSIGDLEQLQKLILSHNKLTELPSGVWRLTNLRCLHLQQNLIEQIPRDLGQLVNLDDLDLSNNHLIDIPESLANLQNLVKLDLSCNKLKSLPPAISQMKNLRMLDCSRNQMESIPPVLAQMESLEQLYLRHNKLRFLPELPCCKTLKELHCGNNQIEVLEAEHLKHLNALSLLELRDNKVKSLPEEITLLQGLERLDLTNNDISSLPCGLGTLPKLKSLSLEGNPLRAIRRDLLTKGTGELLKYLRSRVQEPPNGGLKEEPKT----------AMTFPSQAKINVHAIKTLKTLDYSEKQDASIPDDVFDAVDGNPVANVNFSKNQLTAVPHRIVDLKDTLADINLGFNKLTTIPADFCHLKQLMHIDLRNNLLISLPMELEGLIKLRSVILSFNRF-KSFPEVLYRIPSLETILISSNQVGGIDAVQMKTLSRLSTLDLSNNDIMQVPPELGNCTSLRALMLDGNPFRNPRAAILIKGTDAVLEYLRSRIPT 601          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Zebrafish
Match: shoc2 (SHOC2 leucine rich repeat scaffold protein [Source:NCBI gene;Acc:555476])

HSP 1 Score: 119.013 bits (297), Expect = 1.158e-27
Identity = 141/508 (27.76%), Postives = 245/508 (48.23%), Query Frame = 2
Query:  371 HLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIPVK--------GINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDY--EKIKMLSNLEVLXXXXXXXXXXPP-ELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLR 1849
             LD+S  +I  LP SI  LTQL    +  NK+Q LP ++     L TL+ S N+L SLP  L+ L  L ++DL HN++ E P  +  +  LT L L +N+IT++   ++ L  L +L + +NK++           Q+   +  L          NL  + + HN +  + K+ +     I  L + +N + D+PE I  L S++ L L  N + A+P SL    +L+ L+++ N   +L   +++S  +     L  RN  +  P   GP  Q     ++  +   I++       RA  + KL+ ++         N L S+P+          +NL  N+ +  P  I     SL+ L LSNN + +LP  I +L  LR LD+  NK+  LP  ++ +  L   +L+ N +  T+P  +  +  L  L +   G  ++ +  E+I  L NLE L +++N   +  P EL LC K+  ++++        P I++ G + ++++L+
Sbjct:   83 RLDLSKRSIHLLPSSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVSSLTTLYLRFNRITTVEKDIKNLSKLTMLSIRENKIK-----------QLPAEIGELC---------NLITLDVAHNQLEHLPKE-IGNCTQITNLDLQHNDLLDLPETIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTL-ARNCFQSYPVG-GPS-QFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKD---------NQLTSLPLDFGTWTSMVELNLATNQLTKIPEDICGLV-SLEMLTLSNNLLKKLPYGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQL-TTLPRGIGHLTNLTYLGL---GENLLQHLPEEIGTLENLEDLYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLK 552          

HSP 2 Score: 113.235 bits (282), Expect = 9.179e-26
Identity = 127/474 (26.79%), Postives = 227/474 (47.89%), Query Frame = 2
Query:  272 SSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQ-EEEPKSFG--PGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLT 1651
            SS  +   LT+L L +N +  +  ++  L  L  L +S+N+++SLPDS+ NL +L+  ++  NK++++P  +     L TL   +N + ++ K +  LS LT++ +  N+I + P +I EL  L  LD+++NQ+  +P  +     +  LDL  N L    E  G  A ++++ L  NRL+  P  L   + L+E++L +N IS + +  LS + N+ +LT+A N     P                + + +L     +ME  +   I+  PF +  R+ + S        L M++ Q    P  FG    +  LN AT +     + +      G+V L    L++      N L  +P        ++ ++L  NK    P +I    D LQ L L+NNQ++ LP  I  L+ L  L +  N ++ LPE +  +  L    L+ N   +++P  ++  + L  + + +C L+
Sbjct:   96 SSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVSSLTTLYLRFNRITTVEKDIKNLSKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLPETIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTLARNCFQSYP---------VGGPSQFSTIYSL-----NMEHNR---INKIPFGIFSRAKVLSK-------LNMKDNQLTSLPLDFGTWTSMVELNLATNQ-----LTKIPEDICGLVSLEMLTLSN------NLLKKLPYGIGNLRKLRELDLEENKLESLPNEIAYLKD-LQKLVLTNNQLTTLPRGIGHLTNLTYLGLGENLLQHLPEEIGTLENLEDLYLNDNPNLHSLPFELALCSKLSIMSIENCPLS 533          

HSP 3 Score: 79.337 bits (194), Expect = 6.223e-15
Identity = 60/193 (31.09%), Postives = 101/193 (52.33%), Query Frame = 2
Query:  164 SLNLANRNISEIPNSVYK----INMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYN-QITSMPFTLERLHNLQILDL 727
            SLN+ +  I++IP  ++     ++  N+ D +  S      +W   V   +L L  N ++ I +DI  L  L  L +S+N +  LP  I NL +L+  ++ +NK++ LP++I    +LQ L  + N L +LP+G+  L+NLT + L  N +   P +I  L  L  L L+ N  + S+PF L     L I+ +
Sbjct:  338 SLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV---ELNLATNQLTKIPEDICGLVSLEMLTLSNNLLKKLPYGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTYLGLGENLLQHLPEEIGTLENLEDLYLNDNPNLHSLPFELALCSKLSIMSI 527          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Zebrafish
Match: shoc2 (SHOC2 leucine rich repeat scaffold protein [Source:NCBI gene;Acc:555476])

HSP 1 Score: 119.013 bits (297), Expect = 1.158e-27
Identity = 141/508 (27.76%), Postives = 245/508 (48.23%), Query Frame = 2
Query:  371 HLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIPVK--------GINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDY--EKIKMLSNLEVLXXXXXXXXXXPP-ELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLR 1849
             LD+S  +I  LP SI  LTQL    +  NK+Q LP ++     L TL+ S N+L SLP  L+ L  L ++DL HN++ E P  +  +  LT L L +N+IT++   ++ L  L +L + +NK++           Q+   +  L          NL  + + HN +  + K+ +     I  L + +N + D+PE I  L S++ L L  N + A+P SL    +L+ L+++ N   +L   +++S  +     L  RN  +  P   GP  Q     ++  +   I++       RA  + KL+ ++         N L S+P+          +NL  N+ +  P  I     SL+ L LSNN + +LP  I +L  LR LD+  NK+  LP  ++ +  L   +L+ N +  T+P  +  +  L  L +   G  ++ +  E+I  L NLE L +++N   +  P EL LC K+  ++++        P I++ G + ++++L+
Sbjct:   83 RLDLSKRSIHLLPSSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVSSLTTLYLRFNRITTVEKDIKNLSKLTMLSIRENKIK-----------QLPAEIGELC---------NLITLDVAHNQLEHLPKE-IGNCTQITNLDLQHNDLLDLPETIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTL-ARNCFQSYPVG-GPS-QFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKD---------NQLTSLPLDFGTWTSMVELNLATNQLTKIPEDICGLV-SLEMLTLSNNLLKKLPYGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQL-TTLPRGIGHLTNLTYLGL---GENLLQHLPEEIGTLENLEDLYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLK 552          

HSP 2 Score: 113.235 bits (282), Expect = 9.179e-26
Identity = 127/474 (26.79%), Postives = 227/474 (47.89%), Query Frame = 2
Query:  272 SSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQ-EEEPKSFG--PGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLT 1651
            SS  +   LT+L L +N +  +  ++  L  L  L +S+N+++SLPDS+ NL +L+  ++  NK++++P  +     L TL   +N + ++ K +  LS LT++ +  N+I + P +I EL  L  LD+++NQ+  +P  +     +  LDL  N L    E  G  A ++++ L  NRL+  P  L   + L+E++L +N IS + +  LS + N+ +LT+A N     P                + + +L     +ME  +   I+  PF +  R+ + S        L M++ Q    P  FG    +  LN AT +     + +      G+V L    L++      N L  +P        ++ ++L  NK    P +I    D LQ L L+NNQ++ LP  I  L+ L  L +  N ++ LPE +  +  L    L+ N   +++P  ++  + L  + + +C L+
Sbjct:   96 SSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVSSLTTLYLRFNRITTVEKDIKNLSKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLPETIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTLARNCFQSYP---------VGGPSQFSTIYSL-----NMEHNR---INKIPFGIFSRAKVLSK-------LNMKDNQLTSLPLDFGTWTSMVELNLATNQ-----LTKIPEDICGLVSLEMLTLSN------NLLKKLPYGIGNLRKLRELDLEENKLESLPNEIAYLKD-LQKLVLTNNQLTTLPRGIGHLTNLTYLGLGENLLQHLPEEIGTLENLEDLYLNDNPNLHSLPFELALCSKLSIMSIENCPLS 533          

HSP 3 Score: 79.337 bits (194), Expect = 6.223e-15
Identity = 60/193 (31.09%), Postives = 101/193 (52.33%), Query Frame = 2
Query:  164 SLNLANRNISEIPNSVYK----INMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYN-QITSMPFTLERLHNLQILDL 727
            SLN+ +  I++IP  ++     ++  N+ D +  S      +W   V   +L L  N ++ I +DI  L  L  L +S+N +  LP  I NL +L+  ++ +NK++ LP++I    +LQ L  + N L +LP+G+  L+NLT + L  N +   P +I  L  L  L L+ N  + S+PF L     L I+ +
Sbjct:  338 SLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV---ELNLATNQLTKIPEDICGLVSLEMLTLSNNLLKKLPYGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTYLGLGENLLQHLPEEIGTLENLEDLYLNDNPNLHSLPFELALCSKLSIMSI 527          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Zebrafish
Match: shoc2 (SHOC2 leucine rich repeat scaffold protein [Source:NCBI gene;Acc:555476])

HSP 1 Score: 119.013 bits (297), Expect = 1.158e-27
Identity = 141/508 (27.76%), Postives = 245/508 (48.23%), Query Frame = 2
Query:  371 HLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIPVK--------GINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDY--EKIKMLSNLEVLXXXXXXXXXXPP-ELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLR 1849
             LD+S  +I  LP SI  LTQL    +  NK+Q LP ++     L TL+ S N+L SLP  L+ L  L ++DL HN++ E P  +  +  LT L L +N+IT++   ++ L  L +L + +NK++           Q+   +  L          NL  + + HN +  + K+ +     I  L + +N + D+PE I  L S++ L L  N + A+P SL    +L+ L+++ N   +L   +++S  +     L  RN  +  P   GP  Q     ++  +   I++       RA  + KL+ ++         N L S+P+          +NL  N+ +  P  I     SL+ L LSNN + +LP  I +L  LR LD+  NK+  LP  ++ +  L   +L+ N +  T+P  +  +  L  L +   G  ++ +  E+I  L NLE L +++N   +  P EL LC K+  ++++        P I++ G + ++++L+
Sbjct:   83 RLDLSKRSIHLLPSSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVSSLTTLYLRFNRITTVEKDIKNLSKLTMLSIRENKIK-----------QLPAEIGELC---------NLITLDVAHNQLEHLPKE-IGNCTQITNLDLQHNDLLDLPETIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTL-ARNCFQSYPVG-GPS-QFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKD---------NQLTSLPLDFGTWTSMVELNLATNQLTKIPEDICGLV-SLEMLTLSNNLLKKLPYGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQL-TTLPRGIGHLTNLTYLGL---GENLLQHLPEEIGTLENLEDLYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLK 552          

HSP 2 Score: 113.235 bits (282), Expect = 9.179e-26
Identity = 127/474 (26.79%), Postives = 227/474 (47.89%), Query Frame = 2
Query:  272 SSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQ-EEEPKSFG--PGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLT 1651
            SS  +   LT+L L +N +  +  ++  L  L  L +S+N+++SLPDS+ NL +L+  ++  NK++++P  +     L TL   +N + ++ K +  LS LT++ +  N+I + P +I EL  L  LD+++NQ+  +P  +     +  LDL  N L    E  G  A ++++ L  NRL+  P  L   + L+E++L +N IS + +  LS + N+ +LT+A N     P                + + +L     +ME  +   I+  PF +  R+ + S        L M++ Q    P  FG    +  LN AT +     + +      G+V L    L++      N L  +P        ++ ++L  NK    P +I    D LQ L L+NNQ++ LP  I  L+ L  L +  N ++ LPE +  +  L    L+ N   +++P  ++  + L  + + +C L+
Sbjct:   96 SSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVSSLTTLYLRFNRITTVEKDIKNLSKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLPETIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTLARNCFQSYP---------VGGPSQFSTIYSL-----NMEHNR---INKIPFGIFSRAKVLSK-------LNMKDNQLTSLPLDFGTWTSMVELNLATNQ-----LTKIPEDICGLVSLEMLTLSN------NLLKKLPYGIGNLRKLRELDLEENKLESLPNEIAYLKD-LQKLVLTNNQLTTLPRGIGHLTNLTYLGLGENLLQHLPEEIGTLENLEDLYLNDNPNLHSLPFELALCSKLSIMSIENCPLS 533          

HSP 3 Score: 79.337 bits (194), Expect = 6.223e-15
Identity = 60/193 (31.09%), Postives = 101/193 (52.33%), Query Frame = 2
Query:  164 SLNLANRNISEIPNSVYK----INMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYN-QITSMPFTLERLHNLQILDL 727
            SLN+ +  I++IP  ++     ++  N+ D +  S      +W   V   +L L  N ++ I +DI  L  L  L +S+N +  LP  I NL +L+  ++ +NK++ LP++I    +LQ L  + N L +LP+G+  L+NLT + L  N +   P +I  L  L  L L+ N  + S+PF L     L I+ +
Sbjct:  338 SLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV---ELNLATNQLTKIPEDICGLVSLEMLTLSNNLLKKLPYGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTYLGLGENLLQHLPEEIGTLENLEDLYLNDNPNLHSLPFELALCSKLSIMSI 527          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Zebrafish
Match: lrrc7 (leucine rich repeat containing 7 [Source:ZFIN;Acc:ZDB-GENE-130530-876])

HSP 1 Score: 103.605 bits (257), Expect = 2.590e-22
Identity = 89/297 (29.97%), Postives = 148/297 (49.83%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLT-----------------------IMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTF--SEGFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIIN 1108
            L +L L AN I  + K +     L  L + DN++S+LP +I +L  LK  +I+KN IQ+ PD I+    L  +  S N +  LP+G   L NLT                       I++L  N +   P  I+ L  L +LDL  N+ + +P  LE++H+L+ L L  N LQT   S G    +  + L  NR+      +   ++L+++ L+ NM+ ++  D + K+  + TL + +N++  +P  I  L+ L   D S N++++LP ++G +  L+  + D N    L R I N
Sbjct:   48 LEELYLDANQIEELPKQLFNCQALKKLSMPDNDLSNLPTTIASLVNLKELDISKNGIQEFPDNIKCCKCLSVVEASVNPIAKLPEGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLRILELRENHLKTMPKSIHRLSQLERLDLGSNEFSELPEVLEQIHSLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIESLDADISGCESLEDLLLSANMLQQLP-DSIGKLKKLTTLKVDDNQLTSLPNTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLSDLPREIGN 343          

HSP 2 Score: 86.6557 bits (213), Expect = 4.796e-17
Identity = 65/217 (29.95%), Postives = 113/217 (52.07%), Query Frame = 2
Query:   89 IDIGNSESQNNKAFENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNK 739
            +D+G++E         +L+Q      L L N ++  IP S+ K+      D      E  D+       L  L+L+AN +  +   I  L KL+ L + DN ++SLP++I +L+ L+ F+ + N+++ LP  I     L+T +   N L  LP+ +    N+T+M L  N++   P +I ++  L  L+LS N++ ++PFT  +L +L  L LS N+
Sbjct:  189 LDLGSNEFSE---LPEVLEQIHSLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIESLDADISGCESLEDLLLSANMLQQLPDSIGKLKKLTTLKVDDNQLTSLPNTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLSDLPREIGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLKNLPFTFTKLKDLAALWLSDNQ 402          

HSP 3 Score: 80.8777 bits (198), Expect = 3.331e-15
Identity = 68/268 (25.37%), Postives = 135/268 (50.37%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRML 1090
            LT+L L    + ++  +   L KL  L++ +N++ ++P SI  L+QL+  ++  N+  +LP+ +E    L+ L    N+L+++P  +  L  L  +DL+ N I      I+    L  L LS N +  +P ++ +L  L  L +  N+L +     G  + + +     N L   P  +    +L+  +   N +S++ ++ +    N+  +++ +NK+  +P+EI  +T L  L+LS+N +K LP +   ++ L  L +  N  + L
Sbjct:  140 LTQLFLNDAFLEYLPANFGRLSKLRILELRENHLKTMPKSIHRLSQLERLDLGSNEFSELPEVLEQIHSLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIESLDADISGCESLEDLLLSANMLQQLPDSIGKLKKLTTLKVDDNQLTSLPNTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLSDLPRE-IGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLKNLPFTFTKLKDLAALWLSDNQSKAL 406          

HSP 4 Score: 76.6406 bits (187), Expect = 6.352e-14
Identity = 115/425 (27.06%), Postives = 192/425 (45.18%), Query Frame = 2
Query:  365 LSHLDISDNNISSLPDSITNLTQ-LKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMS 1636
            +S LD S  ++  +P  I +  + L+   ++ N+I++LP Q+ N   L+ LS   N L +LP  +  L NL  +D+S N I EFP  I     L+ ++ S N I  +P    +L NL  L L+   L+     F            RL+K         L+ + L  N +  + K  + ++  +  L + +N+ +++PE +  + SL  L L NN ++ +P S+G + QL+ L +  N    L   I  SG +S++  L   N  ++ P S G  L+ L   T+K D   +  T L  T I  LS     D S    N L S+P                    +  SL+      N +S+LP  I +   +  + +  NK+  LP+ + +M+ L    LS N + N +P   +++  L  L +S
Sbjct:   24 ISVLDYSHCSLQQVPKEIFSFERTLEELYLDANQIEELPKQLFNCQALKKLSMPDNDLSNLPTTIASLVNLKELDISKNGIQEFPDNIKCCKCLSVVEASVNPIAKLPEGFTQLLNLTQLFLNDAFLEYLPANF-----------GRLSK---------LRILELRENHLKTMPKS-IHRLSQLERLDLGSNEFSELPEVLEQIHSLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIESLDADI--SGCESLEDLLLSANMLQQLPDSIG-KLKKL--TTLKVDDNQL--TSLPNT-IGSLSLLEEFDCS---CNELESLP----------------PTIGYLHSLRTFAADENFLSDLPREIGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLKN-LPFTFTKLKDLAALWLS 399          

HSP 5 Score: 57.3806 bits (137), Expect = 6.079e-8
Identity = 95/412 (23.06%), Postives = 182/412 (44.17%), Query Frame = 2
Query:  626 NELYLLTKLDLSYNQITSMP---FTLERLHNLQILDLSQNKLQTFSEGF--CAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEIL---------NSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFK 1792
             E  +++ LD S+  +  +P   F+ ER   L+ L L  N+++   +    C  + ++ +  N L+  P  + +  NLKE+ ++ N I E   D++     +  +  + N IA +PE  + L +L+ L L++  ++ LP + G + +L+ L +  N  + + +        SI R                  L  L R  +  +                  F  L ++ ++I          NSL +IP        ++ ++L  N+       I    +SL+DL LS N + +LP++I  L  L  L +  N++  LP ++  +S L  F  S N++  ++P  +  ++ L+T       L+ +  E I    N+ V+++ +N +  +P E+G   K++ LNL  N  K
Sbjct:   19 GEEEVISVLDYSHCSLQQVPKEIFSFER--TLEELYLDANQIEELPKQLFNCQALKKLSMPDNDLSNLPTTIASLVNLKELDISKNGIQEFP-DNIKCCKCLSVVEASVNPIAKLPEGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLRILELRENHLKTMPK--------SIHR------------------LSQLERLDLGSNE-----------------FSELPEVLEQIHSLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIESLDADI-SGCESLEDLLLSANMLQQLPDSIGKLKKLTTLKVDDNQLTSLPNTIGSLSLLEEFDCSCNEL-ESLPPTIGYLHSLRTFAADENFLSDLPRE-IGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLK 381          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Xenopus
Match: pparg (peroxisome proliferator activated receptor gamma [Source:Xenbase;Acc:XB-GENE-483136])

HSP 1 Score: 295.049 bits (754), Expect = 1.542e-90
Identity = 201/586 (34.30%), Postives = 333/586 (56.83%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVND-EKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMR------NTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             L+K A+KSG LNL+ R ++++P SV++IN+    +  +++ F  SD  WW+   LTKLIL +N +  +S+DISLL  L  LDI DN I SLP +I  LT L+  NI+ NKI++LP ++++   L++L   +N L+ LP  +  LS L  +D+S+N +      + +L  L K +LS N++T++P  + ++ NL+ LD + N L+           + Q++L  N+LT  P +     LKE+ + +N I  +  +HL  + ++  L +  NK+  +PEEIS+L  L  LDLSNND+ +LP +LG +  LK L ++GNP R ++R I+N G   + +YL+ R       TQE+E         +   A        ++   +     ++   +  + + + + N+  S  +  +N + N+ +  P +I +  DS+ D++L  N+IS +   +  L  L  +D+  N +  LP  +  M+ L   ILS+N   +  PDV+ R+  L+T+++S   +  ID  K+  LS L++    NN +  IPP LG CE  ++L+L+GN F+ PR AI++KGT +V+EYLRSRI T
Sbjct:   30 GLIKAARKSGQLNLSARGLTDVPVSVWRINVDTPPEAHQNVDFGGSDR-WWEQTDLTKLILASNKLQLLSEDISLLPALVVLDIHDNQIVSLPCAIKELTNLQKLNISHNKIKQLPKELQHLQNLKSLLLQHNQLEELPDSIGHLSILEELDVSNNCLRSISSSVGQLTGLVKFNLSSNKLTALPTEIGKMKNLKQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLPELPFLTKLKELHVGNNQIQTLGPEHLQNLSSLSVLELRYNKLKVLPEEISLLNGLERLDLSNNDLGSLPCTLGSLPNLKSLQLEGNPLRGIRRDILNKGTQELLKYLKGRVQVPDVKTQEDE--------NSTATAMTLPSESVVNTHAIVTLKTLEYCEKQASLIPEAVFNATGSSFITTVNFSKNQLTEVPARIVEMKDSVCDVNLGFNKISSISLNLCMLLKLTHIDMRNNVLTSLPSEMEAMTRLQSVILSFNRFKH-FPDVLYRIPTLETILISSNQIGSIDPIKMTKLSTLDL---QNNDLLQIPPALGNCESQRALHLEGNPFRNPRAAILAKGTVAVLEYLRSRIPT 602          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Xenopus
Match: pparg (peroxisome proliferator activated receptor gamma [Source:Xenbase;Acc:XB-GENE-483136])

HSP 1 Score: 289.271 bits (739), Expect = 1.174e-88
Identity = 202/583 (34.65%), Postives = 328/583 (56.26%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVND-EKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCE--KIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
              L+K A+KSG LNL+ R ++++P SV++IN+    +  +++ F  SD  WW+   LTKLIL +N +  +S+DISLL  L  LDI DN I SLP +I  LT L+  NI+ NKI++LP ++++   L++L   +N L+ LP  +  LS L  +D+S+N +      + +L  L K +LS N++T++P  + ++ NL+ LD + N L+           + Q++L  N+LT  P +     LKE+ + +N I  +  +HL  + ++  L +  NK+  +PEEIS+L  L  LDLSNND+ +LP +LG +  LK L ++GNP R ++R I+N G   + +YL+ R           PG   ++   ++  +  I +    ATG    SF                  +  +N + N+ +  P +I +  DS+ D++L  N+IS +   +  L  L  +D+  N +  LP  +  M+ L   ILS+N   +  PDV+ R+  L+T+++S   +  ID  K+  LS L++    NN +  IPP LG CE   +++L+L+GN F+ PR AI++KGT +V+EYLRSRI T
Sbjct:   29 HGLIKAARKSGQLNLSARGLTDVPVSVWRINVDTPPEAHQNVDFGGSDR-WWEQTDLTKLILASNKLQLLSEDISLLPALVVLDIHDNQIVSLPCAIKELTNLQKLNISHNKIKQLPKELQHLQNLKSLLLQHNQLEELPDSIGHLSILEELDVSNNCLRSISSSVGQLTGLVKFNLSSNKLTALPTEIGKMKNLKQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLPELPFLTKLKELHVGNNQIQTLGPEHLQNLSSLSVLELRYNKLKVLPEEISLLNGLERLDLSNNDLGSLPCTLGSLPNLKSLQLEGNPLRGIRRDILNKGTQELLKYLKGRVQV--------PGKLFIHPKILEKQASLIPEAVFNATGS---SF------------------ITTVNFSKNQLTEVPARIVEMKDSVCDVNLGFNKISSISLNLCMLLKLTHIDMRNNVLTSLPSEMEAMTRLQSVILSFNRFKH-FPDVLYRIPTLETILISSNQIGSIDPIKMTKLSTLDL---QNNDLLQIPPALGNCESQSLRALHLEGNPFRNPRAAILAKGTVAVLEYLRSRIPT 577          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Xenopus
Match: pparg (peroxisome proliferator activated receptor gamma [Source:Xenbase;Acc:XB-GENE-483136])

HSP 1 Score: 280.411 bits (716), Expect = 3.532e-85
Identity = 198/582 (34.02%), Postives = 331/582 (56.87%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVND-EKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCE--KIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             L+K A+KSG LNL+ R ++++P SV++IN+    +  +++ F  SD  WW+   LTKLIL +N +  +S+DISLL  L  LDI DN I SLP +I  LT L+  NI+ NKI++LP ++++   L++L   +N L+ LP  +  LS L  +D+S+N +      + +L  L K +LS N++T++P  + ++ NL+ LD + N L+           + Q++L  N+LT  P +     LKE+ + +N I  +  +HL  + ++  L +  NK+  +PEEIS+L  L  LDLSNND+ +LP +LG +  LK L ++GNP R ++R I+N     +   L ++ TQE+E         +   A        ++   +     ++   +  + + + + N+  S  +  +N + N+ +  P +I +  DS+ D++L  N+IS +   +  L  L  +D+  N +  LP  +  M+ L   ILS+N   +  PDV+ R+  L+T+++S   +  ID  K+  LS L++    NN +  IPP LG CE   +++L+L+GN F+ PR AI++KGT +V+EYLRSRI T
Sbjct:   26 GLIKAARKSGQLNLSARGLTDVPVSVWRINVDTPPEAHQNVDFGGSDR-WWEQTDLTKLILASNKLQLLSEDISLLPALVVLDIHDNQIVSLPCAIKELTNLQKLNISHNKIKQLPKELQHLQNLKSLLLQHNQLEELPDSIGHLSILEELDVSNNCLRSISSSVGQLTGLVKFNLSSNKLTALPTEIGKMKNLKQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLPELPFLTKLKELHVGNNQIQTLGPEHLQNLSSLSVLELRYNKLKVLPEEISLLNGLERLDLSNNDLGSLPCTLGSLPNLKSLQLEGNPLRGIRRDILNVIIAYLYCSLDVK-TQEDE--------NSTATAMTLPSESVVNTHAIVTLKTLEYCEKQASLIPEAVFNATGSSFITTVNFSKNQLTEVPARIVEMKDSVCDVNLGFNKISSISLNLCMLLKLTHIDMRNNVLTSLPSEMEAMTRLQSVILSFNRFKH-FPDVLYRIPTLETILISSNQIGSIDPIKMTKLSTLDL---QNNDLLQIPPALGNCESQSLRALHLEGNPFRNPRAAILAKGTVAVLEYLRSRIPT 593          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Xenopus
Match: pparg (peroxisome proliferator activated receptor gamma [Source:Xenbase;Acc:XB-GENE-483136])

HSP 1 Score: 280.026 bits (715), Expect = 5.927e-85
Identity = 198/583 (33.96%), Postives = 331/583 (56.78%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVND-EKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCE--KIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
              L+K A+KSG LNL+ R ++++P SV++IN+    +  +++ F  SD  WW+   LTKLIL +N +  +S+DISLL  L  LDI DN I SLP +I  LT L+  NI+ NKI++LP ++++   L++L   +N L+ LP  +  LS L  +D+S+N +      + +L  L K +LS N++T++P  + ++ NL+ LD + N L+           + Q++L  N+LT  P +     LKE+ + +N I  +  +HL  + ++  L +  NK+  +PEEIS+L  L  LDLSNND+ +LP +LG +  LK L ++GNP R ++R I+N     +   L ++ TQE+E         +   A        ++   +     ++   +  + + + + N+  S  +  +N + N+ +  P +I +  DS+ D++L  N+IS +   +  L  L  +D+  N +  LP  +  M+ L   ILS+N   +  PDV+ R+  L+T+++S   +  ID  K+  LS L++    NN +  IPP LG CE   +++L+L+GN F+ PR AI++KGT +V+EYLRSRI T
Sbjct:   29 HGLIKAARKSGQLNLSARGLTDVPVSVWRINVDTPPEAHQNVDFGGSDR-WWEQTDLTKLILASNKLQLLSEDISLLPALVVLDIHDNQIVSLPCAIKELTNLQKLNISHNKIKQLPKELQHLQNLKSLLLQHNQLEELPDSIGHLSILEELDVSNNCLRSISSSVGQLTGLVKFNLSSNKLTALPTEIGKMKNLKQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLPELPFLTKLKELHVGNNQIQTLGPEHLQNLSSLSVLELRYNKLKVLPEEISLLNGLERLDLSNNDLGSLPCTLGSLPNLKSLQLEGNPLRGIRRDILNVIIAYLYCSLDVK-TQEDE--------NSTATAMTLPSESVVNTHAIVTLKTLEYCEKQASLIPEAVFNATGSSFITTVNFSKNQLTEVPARIVEMKDSVCDVNLGFNKISSISLNLCMLLKLTHIDMRNNVLTSLPSEMEAMTRLQSVILSFNRFKH-FPDVLYRIPTLETILISSNQIGSIDPIKMTKLSTLDL---QNNDLLQIPPALGNCESQSLRALHLEGNPFRNPRAAILAKGTVAVLEYLRSRIPT 597          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Xenopus
Match: pparg (peroxisome proliferator activated receptor gamma [Source:Xenbase;Acc:XB-GENE-483136])

HSP 1 Score: 271.552 bits (693), Expect = 3.917e-82
Identity = 198/584 (33.90%), Postives = 323/584 (55.31%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVND-EKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDS--LQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCE--KIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             L+K A+KSG LNL+ R ++++P SV++IN+    +  +++ F  SD  WW+   LTKLIL +N +  +S+DISLL  L  LDI DN I SLP +I  LT L+  NI+ NKI++LP ++++   L++L   +N L+ LP  +  LS L  +D+S+N +      + +L  L K +LS N++T++P  + ++ NL+ LD + N L+           + Q++L  N+LT  P +     LKE+ + +N I  +  +HL  + ++  L +  NK+  +PEEIS+L  L  LDLSNND+ +LP +LG +  LK L ++GNP R ++R I+N G   + +YL+ R TQE+E  +                          AT +           S+ ++N+   + +K +     + S+ P  +F  + S  +  ++ S NQ++E+P                N +  LP  +  M+ L   ILS+N   +  PDV+ R+  L+T+++S   +  ID  K+  LS L++    NN +  IPP LG CE   +++L+L+GN F+ PR AI++KGT +V+EYLRSRI T
Sbjct:   30 GLIKAARKSGQLNLSARGLTDVPVSVWRINVDTPPEAHQNVDFGGSDR-WWEQTDLTKLILASNKLQLLSEDISLLPALVVLDIHDNQIVSLPCAIKELTNLQKLNISHNKIKQLPKELQHLQNLKSLLLQHNQLEELPDSIGHLSILEELDVSNNCLRSISSSVGQLTGLVKFNLSSNKLTALPTEIGKMKNLKQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLPELPFLTKLKELHVGNNQIQTLGPEHLQNLSSLSVLELRYNKLKVLPEEISLLNGLERLDLSNNDLGSLPCTLGSLPNLKSLQLEGNPLRGIRRDILNKGTQELLKYLKGR-TQEDENST--------------------------ATAMTL--------PSESVVNTHAIVTLKTLEYCEKQASLIPEAVFNATGSSFITTVNFSKNQLTEVP-------------ARNNVLTSLPSEMEAMTRLQSVILSFNRFKH-FPDVLYRIPTLETILISSNQIGSIDPIKMTKLSTLDL---QNNDLLQIPPALGNCESQSLRALHLEGNPFRNPRAAILAKGTVAVLEYLRSRIPT 560          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Mouse
Match: Lrrc40 (leucine rich repeat containing 40 [Source:MGI Symbol;Acc:MGI:1914394])

HSP 1 Score: 294.278 bits (752), Expect = 2.339e-90
Identity = 207/587 (35.26%), Postives = 338/587 (57.58%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDE--KSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRM-----RNTQEEEPKSFGPGLQALNRATIKDDS--GFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRI 1858
            + LLK A+ SG LNLA RN+ E+P  V++IN+ ++ +E  +++SF  S   WWD   LTKLI+++N +  +S D+ LL  L+ LDI DN ++SLP +I  L  L+  N++ NK++ LP++I +   L+TL   +N L  +P+G   LS L  +DLS N ++  P     L  L +L+LS NQ+ ++P  + R+  L+ LD   N L+T     G    +  ++L  N+L   P     + LKE+ L  N I ++  +HL  +  I  L +  NK+  +PEE+++L SL  LDLSNND+ +LP SLG++  LK L+++GNP R ++R II  G   + +YLR      R  Q +        L +  R  I   +    +D +D +AT I            D++ ++  +  +  IN + N+    P +I +  + + D++LS N++S + + +  L  L  LD+  N +  LPE +S ++ L    LS+N      P+V+ R++ L+ +++S+  +  +D +K+K++ NL  L++ NN +  IPPELG C ++++L LDGN F+VPR AI+ KGTA+V+EYLR RI
Sbjct:   29 QGLLKAARSSGQLNLAGRNLGEVPQCVWRINV-DIPEEANQNLSF-SSTERWWDQTDLTKLIISSNKLQSLSDDLRLLPALTVLDIHDNQLTSLPSAIRELDNLQKLNVSHNKLKILPEEITSLKNLRTLHLQHNELTCIPEGFEHLSCLEDLDLSSNRLATVPADFALLSSLLRLNLSSNQLKNLPAEISRMKRLKHLDCDANLLETVPPDVGSMESLELLYLRRNKLRVLPEFPSCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGNKLRSVPEEMALLQSLERLDLSNNDISSLPCSLGNL-HLKFLALEGNPLRTIRREIIAKGTQEVLKYLRSKIKDDRTNQNDSVPETAMTLPSEARVNIHAIATLKLLDYSDKQATLI-----------PDDLFDATKTTLITSINFSKNQLCEIPQRIVELKEMVLDINLSFNKLSFISHELCLLQKLTFLDLRNNFLSSLPEEMSSLTKLQTINLSFNRF-KVFPEVLYRISTLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLLQIPPELGNCVQLRTLLLDGNPFRVPRAAILMKGTAAVLEYLRDRI 600          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Mouse
Match: Lrrc1 (leucine rich repeat containing 1 [Source:MGI Symbol;Acc:MGI:2442313])

HSP 1 Score: 108.997 bits (271), Expect = 2.257e-25
Identity = 89/272 (32.72%), Postives = 139/272 (51.10%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVH--QIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSI 1102
            L +L+L AN +  + +    L KL  L +SDN I  LP  I N  QL   ++++N I ++P+ I     LQ    S N L  LP+    L NLT + ++   +   P  I  LY L  L+L  N +T +P +L +L  L+ LDL  N++    E   A +H   +WL  N+L++ P  + N KNL  + ++ N +  + ++ +S + ++  L I+ N +  IPE I  L  LS L L  N +  LP ++GD E L  L +  N    L +SI
Sbjct:   38 LEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNDIPEIPESIAFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEE-ISGLTSLTYLVISQNLLETIPEGIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLTLPKSI 308          

HSP 2 Score: 73.559 bits (179), Expect = 1.430e-13
Identity = 96/363 (26.45%), Postives = 148/363 (40.77%), Query Frame = 2
Query:  473 LPDQIENYLE-LQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVN--RLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLP--ESLSEMSC 1543
            +P++I  Y   L+ L    N L+ LP+    L  L  + LS NEI   PP+I     L +LD+S N I  +P ++     LQ+ D S N L    E F    +   L VN   L   P  + N  NL  + L  N+++ +  D L+++  +  L + NN+I ++PE I  L  L +L L  N +  LP  +G+++ L CL +  N    L   I  SG  S+   +  +N  E  P+  G G          D                                              N+ +  P  I    ++L +L L+ N++  LP +I  L  L  L+   NK+  LP  E +S   C
Sbjct:   27 VPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNDIPEIPESIAFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLP-DSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEI--SGLTSLTYLVISQNLLETIPE--GIGKLKKLSILKLDQ---------------------------------------------NRLTQLPEAIGD-CENLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLPKEEHISGKVC 338          

HSP 3 Score: 67.0106 bits (162), Expect = 2.099e-11
Identity = 50/168 (29.76%), Postives = 91/168 (54.17%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTF--SEGFCAPVHQIWLH 793
            L +L L  N I  + + I  L  L  L +  N +S LP  I NL  L   ++++N++++LP++I     L  L  S N L+++P+G+  L  L+I+ L  N +++ P  I +   LT+L L+ N++ ++P ++ +L  L  L+  +NKL +    E     V +++ H
Sbjct:  176 LEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTYLVISQNLLETIPEGIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLPKEEHISGKVCRLFYH 343          

HSP 4 Score: 64.6994 bits (156), Expect = 1.313e-10
Identity = 50/182 (27.47%), Postives = 84/182 (46.15%), Query Frame = 2
Query:  140 LKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMP 685
            L Q ++   L+L N  I  +P S+  +                       + L  L L  N +S + ++I  L  L  LD+S+N +  LP+ I+ LT L Y  I++N ++ +P+ I    +L  L    N L  LP+ +    NLT + L+ N +   P  I +L  L+ L+   N++ S+P
Sbjct:  170 LTQLRRLEELDLGNNEIYNLPESIGAL-----------------------LHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTYLVISQNLLETIPEGIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLP 328          

HSP 5 Score: 57.3806 bits (137), Expect = 2.666e-8
Identity = 93/351 (26.50%), Postives = 160/351 (45.58%), Query Frame = 2
Query:  764 CAPVHQIWLHVNRLTKFP---IVLPN------KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDS-GFIDQTDLRATGIVKLSFR-NLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGN 1783
            C P+ +   HV  + K     + +P       ++L+E+ L  N + E+  +   ++  +  L +++N+I  +P EI+    L  LD+S ND+  +P S+   + L+     GNP   L                         P+SF P LQ L   ++ D S   + +       +  L  R NL     + L  L  +  + ++L  N+    P  I      L+DL L  NQ+SELP  I +L  L  LD+S N++  LPE +S ++ L++ ++S N +  TIP+ + ++  L  L +    LT +  E I    NL  L ++ N +  +P  +G  +K+ +LN D N
Sbjct:    4 CIPLWRCNRHVEAIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELP-EQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNDIPEIPESIAFCKALQVADFSGNPLTRL-------------------------PESF-PELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRL--EELDLGNNEIYNLPESIGALL-HLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTYLVISQN-LLETIPEGIGKLKKLSILKLDQNRLTQLP-EAIGDCENLTELVLTENRLLTLPKSIGKLKKLSNLNADRN 322          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Mouse
Match: Lrrd1 (leucine rich repeats and death domain containing 1 [Source:MGI Symbol;Acc:MGI:3045299])

HSP 1 Score: 112.079 bits (279), Expect = 5.079e-25
Identity = 150/557 (26.93%), Postives = 261/557 (46.86%), Query Frame = 2
Query:  164 SLNLANRNISEIPNSVYKINMPN---VNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFS-EGFCAP-VHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRY-LRMRNTQEEEPKSFGPGLQALNRATIKDDSG-FIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYE--KIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFK-VPR 1801
            ++NL  + + E P  + K+       ++  +  +F+  D    D + L  L L  N +S I  +I L   L  L+ S N IS +P  +  L  ++   +N N I  LP  +E+   L+TLS   N L  +P  L+ L NL I++L +N+++ F   +  L  L  L+L+ N I S+P  +  L NL+ L +  NKL   + E F  P + ++ L  N+L      + N K L+ ++L  N++  I K  +S   N+ +L++++N I ++P++I  L +L  L ++ N M  +   +  +  +  L   GN    +   I N     I R  L   N        F  GL AL        +G +I +        V +SF      S ++L+         + LN NK ++F   +   ++ L+ LDL+ NQI  +P+ IS++  L  L +S NK    P+ L  +  L    +S N +   IP  +S++  +Q L +S+   T    E  +++ L  L +   S   ++ +P E+    ++K LN+  N  K +P+
Sbjct:  139 TVNLDAKGLQEFPVDIVKVKYVKYLYLDKNQIKNFQGIDPG--DLLGLEILSLQENGLSSIPLEIQLFHNLKILNASYNEISQIPKELLQLENMRQLLLNSNHIDTLPSGLEHLRYLETLSLGKNMLTYIPDSLSSLKNLRILNLEYNQLTIFSKSLCFLPKLNSLNLTGNMIGSLPKEVRELKNLESLLMDHNKLTFLAVEIFQLPKIKELHLADNKLEAISPKIENFKELRLLNLDKNLLQSIPK-KISHCVNLESLSLSDNNIEELPKKIRKLKNLRQLHVNRNKMITMTEEISHLSNIHILEFSGNQITHVPIEIKN--CRKITRVELNYNNIM-----YFPVGLCALQSLDYLSFNGNYISEIP------VDMSF------SKQLLH---------LELNRNKLTVFSKHLCSLTN-LEYLDLAKNQIMTIPSCISAMVSLHVLILSDNKFESFPKELCSLKNLRVLDISENKL-QKIPLEISKLKRIQKLNLSNNIFTNFPVELCQLQTLEELNISQTSGKKLTRLPEEVSHMTQLKILNISNNAIKDIPK 662          

HSP 2 Score: 108.227 bits (269), Expect = 8.885e-24
Identity = 116/420 (27.62%), Postives = 204/420 (48.57%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLP-NKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCL 1546
            L  L++  N ++F++ +I  L K+  L ++DN + ++   I N  +L+  N++KN +Q +P +I + + L++LS S N ++ LPK +  L NL  + ++ N++     +I+ L  +  L+ S NQIT +P  ++    +  ++L+ N +  F  G CA   +  +  + N +++ P+ +  +K L  + L  N ++  +K HL  + N+  L +A N+I  IP  IS + SL  L LS+N  ++ P  L  ++ L+ L I  N  + +   I  S    I++     N     P      LQ L    I   SG                 + L  L +E+    H   +K +N++ N     P  I +   SL     SNNQIS LP++  SL  L+ LD+  N +  LP  + ++S L
Sbjct:  322 LESLLMDHNKLTFLAVEIFQLPKIKELHLADNKLEAISPKIENFKELRLLNLDKNLLQSIPKKISHCVNLESLSLSDNNIEELPKKIRKLKNLRQLHVNRNKMITMTEEISHLSNIHILEFSGNQITHVPIEIKNCRKITRVELNYNNIMYFPVGLCALQSLDYLSFNGNYISEIPVDMSFSKQLLHLELNRNKLTVFSK-HLCSLTNLEYLDLAKNQIMTIPSCISAMVSLHVLILSDNKFESFPKELCSLKNLRVLDISENKLQKIPLEI--SKLKRIQKLNLSNNIFTNFPVELC-QLQTLEELNISQTSG-----------------KKLTRLPEEV---SHMTQLKILNISNNAIKDIPKNIGELR-SLVSFYASNNQISSLPSSFLSLEVLQSLDLRGNNMTALPSGIYKLSSL 716          

HSP 3 Score: 58.9214 bits (141), Expect = 1.636e-8
Identity = 98/423 (23.17%), Postives = 190/423 (44.92%), Query Frame = 2
Query:  548 KGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQI------------------------TSMPFTLERLHNLQILDLSQNKLQTFSEGF--CAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKD-DSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLV---MSHCGLTIIDYEKIKMLSNLEVL 1699
            KGL+  S+   ++L    + EFP  I ++  +  L L  NQI                        +S+P  ++  HNL+IL+ S N++    +       + Q+ L+ N +   P  L + + L+ +SL  NM++ I  D LS + N+  L +  N++    + +  L  L++L+L+ N + +LP  + +++ L+ L +D N    L   I       IK      N  E    +  P ++      + + D   +     + +  V L   +L+D      N++  +P        ++ +++N NK      +I   S+ +  L+ S NQI+ +P  I +   + R+++++N I   P  L  +  L +  LS+N  GN I ++   M++ + L+   ++   LT+   + +  L+NLE L
Sbjct:  129 KGLDMKSDNFTVNLDAKGLQEFPVDIVKVKYVKYLYLDKNQIKNFQGIDPGDLLGLEILSLQENGLSSIPLEIQLFHNLKILNASYNEISQIPKELLQLENMRQLLLNSNHIDTLPSGLEHLRYLETLSLGKNMLTYIP-DSLSSLKNLRILNLEYNQLTIFSKSLCFLPKLNSLNLTGNMIGSLPKEVRELKNLESLLMDHNKLTFLAVEIFQ--LPKIKELHLADNKLE----AISPKIENFKELRLLNLDKNLLQSIPKKISHCVNLESLSLSD------NNIEELPKKIRKLKNLRQLHVNRNKMITMTEEISHLSN-IHILEFSGNQITHVPIEIKNCRKITRVELNYNNIMYFPVGLCALQSLDY--LSFN--GNYISEIPVDMSFSKQLLHLELNRNKLTVFS-KHLCSLTNLEYL 532          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Mouse
Match: Lrrc1 (leucine rich repeat containing 1 [Source:MGI Symbol;Acc:MGI:2442313])

HSP 1 Score: 109.383 bits (272), Expect = 1.231e-24
Identity = 115/382 (30.10%), Postives = 179/382 (46.86%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVH--QIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSI------INSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIP-------VKGINLNGNKFSIFPLKIFQ 1393
            L +L+L AN +  + +    L KL  L +SDN I  LP  I N  QL   ++++N I ++P+ I     LQ    S N L  LP+    L NLT + ++   +   P  I  LY L  L+L  N +T +P +L +L  L+ LDL  N++    E   A +H   +WL  N+L++ P  + N KNL  + ++ N +  + ++ +S + ++  L I+ N +  IPE I  L  LS L L  N +  LP ++GD E L  L +  N    L +SI       N  AD        RN     PK  G G  +L    I+D+   + +     +  V+L   ++A       N LH +P       +K + L+ N+    PL  FQ
Sbjct:   38 LEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNDIPEIPESIAFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEE-ISGLTSLTYLVISQNLLETIPEGIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLTLPKSIGKLKKLSNLNAD--------RNKLVSLPKEIG-GCCSLTMFCIRDNR--LTRLPAEVSQAVELHVLDVAG------NRLHHLPLSLTTLKLKALWLSDNQSQ--PLLTFQ 399          

HSP 2 Score: 78.1814 bits (191), Expect = 1.331e-14
Identity = 101/389 (25.96%), Postives = 159/389 (40.87%), Query Frame = 2
Query:  473 LPDQIENYLE-LQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVN--RLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTL 1627
            +P++I  Y   L+ L    N L+ LP+    L  L  + LS NEI   PP+I     L +LD+S N I  +P ++     LQ+ D S N L    E F    +   L VN   L   P  + N  NL  + L  N+++ +  D L+++  +  L + NN+I ++PE I  L  L +L L  N +  LP  +G+++ L CL +  N    L   I  SG  S+   +  +N  E  P+  G G          D                                              N+ +  P  I    ++L +L L+ N++  LP +I  L  L  L+   NK+  LP+ +     L+ F +  N +   +P  VS+   L  L
Sbjct:   27 VPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNDIPEIPESIAFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYL-PDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEI--SGLTSLTYLVISQNLLETIPE--GIGKLKKLSILKLDQ---------------------------------------------NRLTQLPEAIGD-CENLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTMFCIRDNRL-TRLPAEVSQAVELHVL 363          

HSP 3 Score: 56.6102 bits (135), Expect = 7.494e-8
Identity = 87/319 (27.27%), Postives = 149/319 (46.71%), Query Frame = 2
Query:  833 KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDS-GFIDQTDLRATGIVKLSFR-NLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGN 1783
            ++L+E+ L  N + E+  +   ++  +  L +++N+I  +P EI+    L  LD+S ND+  +P S+   + L+     GNP   L                         P+SF P LQ L   ++ D S   + +       +  L  R NL     + L  L  +  + ++L  N+    P  I      L+DL L  NQ+SELP  I +L  L  LD+S N++  LPE +S ++ L++ ++S N +  TIP+ + ++  L  L +    LT +  E I    NL  L ++ N +  +P  +G  +K+ +LN D N
Sbjct:   36 RSLEELLLDANQLREL-PEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNDIPEIPESIAFCKALQVADFSGNPLTRL-------------------------PESF-PELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRL--EELDLGNNEIYNLPESIGALL-HLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTYLVISQN-LLETIPEGIGKLKKLSILKLDQNRLTQLP-EAIGDCENLTELVLTENRLLTLPKSIGKLKKLSNLNADRN 322          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Mouse
Match: Shoc2 (Shoc2, leucine rich repeat scaffold protein [Source:MGI Symbol;Acc:MGI:1927197])

HSP 1 Score: 105.531 bits (262), Expect = 2.800e-23
Identity = 127/461 (27.55%), Postives = 223/461 (48.37%), Query Frame = 2
Query:  371 HLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHV--NRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSL-GDMEQLKCLSIDGNPFRM----------------LKRSIINS---GADSIKRYLRMRNTQEEE----PKSFGP--GLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSL-HSI----PVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLT 1651
             LD+S  +I  LP S+  LTQL    +  NK+Q LP ++   + L TL+ S N+L SLP  L+ L  L ++DL HN++ E P  +  L  LT L L +N+IT++   ++ L  L +L + +NK++          + I L V  N+L   P  + N   +  + L HN + ++  D +  + ++  L +  N+++ IP  ++  ++L  L+L NN++  LP SL   + +L  L++  N F++                ++ + IN    G  S  + L   N ++ +    P  FG    +  LN AT +     + +     +G+V L    +  LS+ +L  L H +     ++ ++L  NK    P +I    D LQ L L+NNQ+S LP  I  L+ L  L +  N +  LPE +  +  L    L+ N   +++P  ++  + L  + + +C L+
Sbjct:  104 RLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLP-DTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQ-----LTKIPEDVSGLVSLE---VLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKD-LQKLVLTNNQLSTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLS 554          

HSP 2 Score: 93.2041 bits (230), Expect = 2.633e-19
Identity = 87/298 (29.19%), Postives = 146/298 (48.99%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLER------------------------LHNLQILDLSQNKLQTFSEGFCAPVHQIW---LHVNRLTKFP--IVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSI 1102
            L  L L  N +  I   +  LD L+ L +  N I+++   I NL +L   +I +NKI++LP +I     L TL  ++N L+ LPK +   + +T +DL HN++ + P  I  L  L +L L YN+++++P +L +                        L  L  L L++N  Q +  G  +    I+   +  NR+ K P  I    K L ++++  N ++ +  D      ++  L +A N++  IPE++S L SL  L LSNN +K LP  LG++ +L+ L ++ N    L   I
Sbjct:  171 LRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEI 467          

HSP 3 Score: 92.0485 bits (227), Expect = 6.288e-19
Identity = 114/435 (26.21%), Postives = 202/435 (46.44%), Query Frame = 2
Query:  581 MDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGF--CAPVHQIWLHVNRLTKFP-IVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKG---------INLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYN-------DIGN---------------TIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGN 1783
            +DLS   I   PP + EL  LT+L L  N++ S+P  +  L NL  L LS+N L +  +       +  + L  N+L + P +V    +L  + L  N I+ + KD +  +P +  L+I  NKI  +P EI  L +L  LD+++N ++ LP  +G+  Q+  L +  N    L  +I N    S+ R     N     P+S              ++   + ++ L  + +VKL+   LA       N     PV G         +N+  N+ +  P  IF  +  L  L++ +NQ++ LP    + + +  L+++ N++  +PE +S +  L   ILS N        +GN               ++P+ ++ +  LQ LV+++  L+ +    I  L+NL  L +  N ++++P E+G  E ++ L L+ N
Sbjct:  105 LDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKD-IKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLPDTIGN--LSSLNRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL--SSLVKLNSLTLAR------NCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTLP-RGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN 527          

HSP 4 Score: 73.559 bits (179), Expect = 4.030e-13
Identity = 49/147 (33.33%), Postives = 78/147 (53.06%), Query Frame = 2
Query:  365 LSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVN 799
            LS L++ DN ++SLP      T +   N+  N++ K+P+ +   + L+ L  S N LK LP GL  L  L  +DL  N++   P +I  L  L KL L+ NQ++++P  +  L NL  L L +N L    E  G    + +++L+ N
Sbjct:  381 LSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN 527          

HSP 5 Score: 56.6102 bits (135), Expect = 7.823e-8
Identity = 50/205 (24.39%), Postives = 89/205 (43.41%), Query Frame = 2
Query:  164 SLNLANRNISEIPNSVYK----INMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLT-----------------------------------------------IMDLSHNEISEFPPQI 625
            SLN+ +  I++IP  ++     ++  N+ D +  S      +W     + +L L  N ++ I +D+S L  L  L +S+N +  LP  + NL +L+  ++ +NK++ LP++I    +LQ L  + N L +LP+G+  L+NLT                                               IM + +  +S  PPQI
Sbjct:  359 SLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTS---MVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQI 560          
BLAST of Leucine-rich repeat-containing protein 40 vs. UniProt/SwissProt
Match: sp|Q7SXW3|LRC40_DANRE (Leucine-rich repeat-containing protein 40 OS=Danio rerio OX=7955 GN=lrrc40 PE=2 SV=1)

HSP 1 Score: 315.464 bits (807), Expect = 9.900e-98
Identity = 206/586 (35.15%), Postives = 335/586 (57.17%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKS-ISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQ------EEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             LLK A+KSG LNL+ R ++E+P SV+++N+    + K  +SF   D  WW+   LTKL+L++N +  I  D+ LL  L  LDI DN +SSLPDSI +L QL+   ++ NK+ +LP  +     L+ L    N ++ +P+ L  L NL  +DLS+N + + P  +  L  L KLDLS N++ S+P  + ++ NL++LD S+N++++          + Q++L  N+L   P +   K LKE+   +N I  +  +HL  +  +  L + +NK+  +PEEI++L  L  LDL+NND+ +LP  LG + +LK LS++GNP R ++R ++  G   + +YLR R  +      +EEPK+          A        I+   ++    +  S +  A + D++ +++   PV  +N + N+ +  P +I    DSL D++L  N+++ +P     L  L  +D+  N +  LP  L  +  L   ILS+N    + P+V+ R+  L+T+++S   +  ID  ++K LS L  L++SNN I  +PPELG C  +++L LDGN F+ PR AI+ KGT +V+EYLRSRI T
Sbjct:   28 GLLKAARKSGQLNLSGRGLTEVPASVWRLNLDTPQEAKQNVSFGAEDR-WWEQTDLTKLLLSSNKLQSIPDDVKLLPALVVLDIHDNQLSSLPDSIGDLEQLQKLILSHNKLTELPSGVWRLTNLRCLHLQQNLIEQIPRDLGQLVNLDELDLSNNHLIDIPESLANLQNLVKLDLSCNKLKSLPPAISQMKNLRMLDCSRNQMESIPPVLAQMESLEQLYLRHNKLRYLPELPCCKTLKELHCGNNQIEVLEAEHLKHLNALSLLELRDNKVKSLPEEITLLQGLERLDLTNNDISSLPCGLGTLPKLKSLSLEGNPLRAIRRDLLTKGTGELLKYLRSRVQEPPNGGLKEEPKT----------AMTFPSQAKINVHAIKTLKTLDYSEKQDATIPDDVFDAVDGNPVANVNFSKNQLTAVPHRIVDLKDSLADINLGFNKLTTIPADFCHLKQLMHIDLRNNLLISLPMELEGLIKLRSVILSFNRF-KSFPEVLYRIPSLETILISSNQVGGIDAVQMKTLSRLSTLDLSNNDIMQVPPELGNCTSLRALMLDGNPFRNPRAAILIKGTDAVLEYLRSRIPT 601          
BLAST of Leucine-rich repeat-containing protein 40 vs. UniProt/SwissProt
Match: sp|Q5ZLN0|LRC40_CHICK (Leucine-rich repeat-containing protein 40 OS=Gallus gallus OX=9031 GN=LRRC40 PE=2 SV=1)

HSP 1 Score: 314.694 bits (805), Expect = 2.764e-97
Identity = 197/593 (33.22%), Postives = 348/593 (58.68%), Query Frame = 2
Query:  104 SESQNNKAFENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVND-EKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKL---SFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
            +E Q+    + L++ A+KSG LNLA R + E+P  V++IN+    +  +++SF  +D  WW+   LTKLIL +N +  +S+D+ LL  L+ LD+ DN ++SLP ++  L  L+  +++ NK++ +P+++     L+ L   +N L  LP G   L +L  +DLS+N +++ P     L  L +L+L+ NQ+  +P  +  + +L+ LD ++N L++        A + Q++L  N+L   P +   K LKE+    N I  +  ++L  + ++  L + +NKI  +P+EI++L  L  LDL+NND+  LP +LG++ QLK L+++GNP R ++R ++  G   + +YLR R   ++   +  P + A+   T+  +S    + ++ A   +KL   S + +A + D++ +++ S PV  +N + N+ +  P +I +  DS+ D++   N+IS +   + +L  L  LDI  N +  LPE +  ++ L    LS+N      P V+ RM  L+T+++S+  +  ID  ++K +  L  L++ NN +  +PPELG CE +++L L+GN F+ PR AI++KGTA+V+EYLRSRI T
Sbjct:   20 AEEQSPAVPQGLIRAARKSGQLNLAGRGLGEVPQHVWRINLDTPEEAHQNLSFGAADR-WWEQTDLTKLILASNQLRCLSEDVRLLPALTVLDVHDNQLTSLPSALGQLENLQKLDVSHNKLKSIPEELLQLSHLKGLLLQHNELSHLPDGFGQLVSLEELDLSNNHLTDIPKSFALLINLVRLNLACNQLKDLPADISAMKSLRQLDCTKNYLESVPSELASMASLEQLYLRKNKLRSLPELPSCKLLKELHAGENQIEILNAENLKHLNSLSVLELRDNKIKSVPDEITLLQKLERLDLANNDISRLPYTLGNLSQLKFLALEGNPLRTIRRDLLQKGTQELLKYLRSRIQDDKASPNEEPPVTAM---TLPSES----RINMHAITTLKLLDYSEKQVAVIPDDVFSAVRSNPVTSVNFSKNQLTAIPPRIVELKDSVCDVNFGFNKISSVSLELCTLHKLTHLDIRNNVLTSLPEEMEALTRLQVINLSFNRF-KVFPSVLYRMLALETILLSNNQVGSIDPLQLKKMEQLGTLDLQNNDLLQVPPELGNCETLRTLLLEGNPFRTPRAAILAKGTAAVLEYLRSRIPT 603          
BLAST of Leucine-rich repeat-containing protein 40 vs. UniProt/SwissProt
Match: sp|Q9H9A6|LRC40_HUMAN (Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1)

HSP 1 Score: 300.442 bits (768), Expect = 6.216e-92
Identity = 207/589 (35.14%), Postives = 341/589 (57.89%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDE--KSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMR-----NTQEEEPKSFGPGLQALNRATIKD--DSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
            + LLK A+KSG LNL+ RN+SE+P  V++IN+ ++ +E  +++SF  ++  WW+   LTKLI++ N +  ++ D+ LL  L+ LDI DN ++SLP +I  L  L+  N++ NK++ LP++I N   L+ L   +N L  + +G   LSNL  +DLS+N ++  P   + L  L +L+LS N++ S+P  + R+  L+ LD + N L+T          +  ++L  N+L   P       LKE+ +  N I  +  +HL  + +I  L + +NK+  +P+EI +L SL  LDLSNND+ +LP SLG++  LK L+++GNP R ++R II+ G   + +YLR +      +Q E        L + +R  I        +D +D +AT I            DE+ +++ S  V  IN + N+    P ++ +  + + D+DLS N++S +   +  L  L  LD+  N +  LPE +  +  L    LS+N     +P+V+ R+  L+T+++S+  +  +D +K+KM+ NL  L++ NN +  IPPELG C  +++L LDGN F+VPR AI+ KGTA+++EYLR RI T
Sbjct:   29 QGLLKAARKSGQLNLSGRNLSEVPQCVWRINV-DIPEEANQNLSFGATER-WWEQTDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL-HLKFLALEGNPLRTIRREIISKGTQEVLKYLRSKIKDDGPSQSESATETAMTLPSESRVNIHAIITLKILDYSDKQATLI-----------PDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRF-KMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRVPRAAILMKGTAAILEYLRDRIPT 602          
BLAST of Leucine-rich repeat-containing protein 40 vs. UniProt/SwissProt
Match: sp|Q6GPJ5|LRC40_XENLA (Leucine-rich repeat-containing protein 40 OS=Xenopus laevis OX=8355 GN=lrrc40 PE=2 SV=1)

HSP 1 Score: 300.442 bits (768), Expect = 8.114e-92
Identity = 202/586 (34.47%), Postives = 340/586 (58.02%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVND-EKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMR------NTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             L+K A+KSG LNL+ R ++E+P SV++IN+    +  +++ F  SD  WW+   LTKLIL +N +  +S+DISLL  L  LDI DN I+SLP +I  LT L+  NI+ NKI++LP+++++   L++    +N L+ LP  +  LS L  +D+S+N +      + +L  L K +LS N++T++P  + ++ NL+ LD + N L+           + Q++L  N+LT  P +     LKE+ + +N I  +  +HL  + ++  L +  NK+  +P+EIS+L  L  LDLSNND+ +LP +LG +  LK L +DGNP R ++R I+N G   + +YL+ R       TQE    +  P   A+   T+  DS  I+   +     ++   +  + + + + N+  S P+  +N + N+ +  P +I +  DS+ D++L  N+IS +   +  L  L  LD+  N +  LP  +  ++ L   ILS+N   +  PDV+  +  L+T+++S   +  ID  ++K ++ L  L++ NN +  IPP LG CE +++L+L+GN F+ PR  I++KGT +++EYLRSRI T
Sbjct:   30 GLIKAARKSGQLNLSARGLTEVPVSVWRINVDTPPEAHQNVDFGGSDR-WWEQTDLTKLILASNKLQALSEDISLLPALVVLDIHDNQIASLPCAIRELTNLQKLNISHNKIKQLPNELQHLQNLKSFLLQHNQLEELPDSIGHLSILEELDVSNNCLRSVSSSVGQLTGLVKFNLSSNKLTALPTEIGKMKNLRQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLPELPFLTKLKELHVGNNQIQTLGPEHLQNLSSLSVLELRYNKLKVLPKEISLLKGLERLDLSNNDIGSLPDTLGSLPNLKSLQLDGNPLRGIRRDILNKGTQELLKYLKGRVQTPDMTTQE----AANPPDTAM---TLPSDS-VINAHAIMTLKTLEYCEKQASLIPEAVFNAAASSPITTVNFSKNQLTEVPARIVEMKDSVYDVNLGFNKISSISLNLCMLLKLTHLDMRNNALASLPPEMEALTRLQSIILSFNRFKH-FPDVLYTIPNLETILISSNQIGSIDPIQLKKMTKLSTLDLQNNDLLQIPPALGNCESLRALHLEGNPFRNPRATILAKGTVAILEYLRSRIPT 605          

HSP 2 Score: 74.7146 bits (182), Expect = 1.117e-12
Identity = 59/209 (28.23%), Postives = 109/209 (52.15%), Query Frame = 2
Query:  122 KAFENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSL-PKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQ 745
            K   N L+  +   S  L +  + E+P+S+  +++    D  +       SS      L K  L++N ++ +  +I  +  L  LD + N + ++P S+  +  L+   + +NK+  LP+ +    +L+ L    N +++L P+ L  LS+L++++L +N++   P +I+ L  L +LDLS N I S+P TL  L NL+ L L  N L+
Sbjct:  141 KQLPNELQHLQNLKSFLLQHNQLEELPDSIGHLSILEELDVSNNCLRSVSSSVGQLTGLVKFNLSSNKLTALPTEIGKMKNLRQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLPE-LPFLTKLKELHVGNNQIQTLGPEHLQNLSSLSVLELRYNKLKVLPKEISLLKGLERLDLSNNDIGSLPDTLGSLPNLKSLQLDGNPLR 348          
BLAST of Leucine-rich repeat-containing protein 40 vs. UniProt/SwissProt
Match: sp|Q4R3P6|LRC40_MACFA (Leucine-rich repeat-containing protein 40 OS=Macaca fascicularis OX=9541 GN=LRRC40 PE=2 SV=1)

HSP 1 Score: 300.056 bits (767), Expect = 8.711e-92
Identity = 206/589 (34.97%), Postives = 340/589 (57.72%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDE--KSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMR-----NTQEEEPKSFGPGLQALNRATIKD--DSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
            + LLK A+KSG LNL+ RN+SE+P  V++IN+ ++ +E  +++SF  ++  WW+   LTKLI++ N +  ++ D+ LL  L+ LDI DN ++SLP ++  L  L+  N++ NK++  P++I N   L+ L   +N L  + +G   LSNL  +DLS+N ++  P   + L  L +L+LS NQ+ S+P  + R+  L+ LD + N L+T          +  ++L  N+L   P       LKE+ +  N I  +  +HL  + +I  L + +NK+  +P+EI +L SL  LDLSNND+ +LP SLG++  LK L+++GNP R ++R IIN G   + +YLR +      +Q E        L + +R  I        +D +D +AT I            DE+ N++ S  +  IN + N+    P ++ +  + + D++LS N++S +   +  L  L  LD+  N +  LPE +  +  L    LS+N     +P+V+ R+  L+T+++S+  +  +D +K+KM+ NL  L++ NN +  IPPELG C  +++L LDGN F+VPR AI+ KGTA+++EYLR RI T
Sbjct:   29 QGLLKAARKSGQLNLSGRNLSEVPQCVWRINV-DIPEEANQNLSFGATER-WWEQTDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAMRELENLQKLNVSHNKLKIFPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNRLTTVPASFSSLSSLVRLNLSSNQLKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLQSLERLDLSNNDISSLPYSLGNL-HLKFLALEGNPLRTIRREIINKGTQEVLKYLRSKIKDDGPSQSESAAETAMTLPSESRVNIHAIITLKILDYSDKQATLI-----------PDEVFNAVKSNIITSINFSKNQLCEIPKRMVELKEMVSDVNLSFNKLSFISLELCMLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRF-KMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRVPRAAILIKGTAAILEYLRDRIPT 602          
BLAST of Leucine-rich repeat-containing protein 40 vs. TrEMBL
Match: K1QH70 (Leucine-rich repeat-containing protein 40 OS=Crassostrea gigas OX=29159 GN=CGI_10024852 PE=4 SV=1)

HSP 1 Score: 334.724 bits (857), Expect = 1.726e-102
Identity = 208/581 (35.80%), Postives = 343/581 (59.04%), Query Frame = 2
Query:  137 LLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYL--RMRNTQEEEPKSFGPGLQALNRATIKDDSG-FIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
            +LKQA+K+G LNL+ RN+S +P++V+++N+    + + +S + +D  WW+   LTKLIL +N ++ IS++IS    LS LDI DN + SLP SI  L  L   ++++NK+++LP+ +     L++L   YN L  + +G+  L  L  +DLS+N++SE PPQ+  LY + K ++S N+++S+P  +  ++ L+ LD++ N+L    E  G    + Q++L  N+L+  P++   KNLKEI L +N I +IT +HL  + ++  L I +NKI+++PEEI+ L+ L  LDL+NND+  LP  LG +  LK + +DGNP + ++R II  G   +K+YL  R+ + Q  EP +   G+Q      I   SG  +   D++ +  +  S +    + D+I        V  +NL+ N+F+  P  +     +L++ +   N++++L   IS    L  LD+  N +  LP  +  +  +   +LS N    T+P  +  M  L+ +   +  +T ID    K L  L  L++ NN I  +PPELG C +IKSL L+GN F+ PRPAI++KGT +++EYLRSRIV+
Sbjct:   29 ILKQARKTGQLNLSGRNLSTVPDTVWRLNLDVPEEARDVSLDNTDERWWEQTELTKLILASNLLTEISQEISNFQALSVLDIHDNRLESLPQSIRELENLVKLDVSRNKLKELPESVTYLRNLRSLHVEYNELVRVSEGIGHLDKLEDLDLSNNQLSELPPQVGHLYHVLKFNVSNNRLSSLPPEIGSMNALKCLDVTHNQLTHLPEDLGNLPNLEQLYLRHNQLSGIPLLKNCKNLKEIHLGNNQIRKITAEHLQHLESVTVLDIRDNKISELPEEITCLSGLQRLDLTNNDLTGLPFVLGTITSLKSIVLDGNPMKSIRRDIIMRGTVELKKYLCSRIEDPQPVEPTN--KGIQNGGDTGIVGGSGEGLKAHDIQQSKSLDYSNKKATAVPDDIWEVAMKAGVTSVNLSKNQFTDLPSNLILLESTLKEFNFGFNKLTKLNPDISLFLRLTTLDLRNNGLSDLPRDMESLQDMREIVLSCNRF-TTLPSSLYEMKKLEIIFADNNKITTIDAAGFKNLPMLATLDLQNNNIDQVPPELGNCTQIKSLLLNGNAFRNPRPAILTKGTLALLEYLRSRIVS 606          
BLAST of Leucine-rich repeat-containing protein 40 vs. TrEMBL
Match: A0A5N5PX81 (Uncharacterized protein OS=Pangasianodon hypophthalmus OX=310915 GN=PHYPO_G00105910 PE=4 SV=1)

HSP 1 Score: 330.872 bits (847), Expect = 4.147e-101
Identity = 207/580 (35.69%), Postives = 344/580 (59.31%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINM-PNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             LLK A+KSG LNL+ R +SE+P SV++IN+ P    ++++SF  ++  WW+   LTKL+L++N +  IS+DI LL  L  LDI DN +++LP SI  L QL+   ++ NK+ +LP ++ +   L+ L    N L+ LP  L  L +L  +D+S+N++   P  + +L  L KL+LS+N + S+P  +  + NL++LD S+N+L++        A + Q++L  N+L   P +   K LKE+   +N I  +  DHL  +  +  L + +NK+  +PEEI++L  L  LDL+NND+ ++P  LG +  LK L+++GNP R ++R I+  G   + +YLR R   +E+P   G   +  N A        I+   ++    +  S +  A + D++ +++++ PV  +N + N+ +  P +I +  D+L D++L  N+IS +P   S L  L  +D+  N +  LP  L  ++ L   ILS+N      PDV+ R+  L+T+++S+  +  ID  ++K+L  L  L++ NN I  +PPELG C  +++L LDGN F+ PR AI++KGT +++EYLRSRI T
Sbjct:   28 GLLKSARKSGQLNLSGRGLSEVPQSVWRINVDPPEEAQQNVSFSAAE-RWWEQTDLTKLLLSSNKLQTISEDIKLLPALVVLDIHDNQLTTLPASIGELEQLQKLILSHNKLTELPTELWSLTNLRCLHLQQNLLEQLPADLGQLCHLEDLDISNNKLMAVPDSLADLSNLVKLNLSFNNLKSLPSAISGMKNLRMLDCSRNQLESVPPVLAQMASLEQLYLRHNKLRFLPELPSCKTLKELHCGNNQIEVLEADHLKHLSALSVLELRDNKVKSLPEEITVLQGLERLDLTNNDISSVPCGLGTLPNLKSLALEGNPLRTIRRDILTKGTSELLKYLRSR--IQEQPD--GKAKEGPNTAMTLPSQAKINVHAIKTLKTLDYSEKQEASIPDDVFDAVNNSPVANVNFSKNQLTAVPPRIVELRDTLADINLGCNKISTIPLEFSKLQQLVHIDLRNNLLTSLPVELEALTKLRSIILSFNKF-KCFPDVLYRILTLETILISNNQVGAIDPVQLKLLDRLSTLDLQNNDIMQVPPELGNCTSLRALLLDGNPFRNPRAAIVAKGTDALLEYLRSRIPT 601          
BLAST of Leucine-rich repeat-containing protein 40 vs. TrEMBL
Match: A0A4W5P7F3 (Leucine rich repeat containing 40 OS=Hucho hucho OX=62062 PE=4 SV=1)

HSP 1 Score: 323.939 bits (829), Expect = 2.010e-98
Identity = 198/580 (34.14%), Postives = 344/580 (59.31%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKS-ISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             LLK A+KSG LNL+ R ++E+P SV+++N+    + K  +SF  +D  WWD   LTKL+L++N +  +S+D+ LL  L+ LD+ DN ++SLP SI  L  L+  +++ NK+++LP+++ +   L  L    N L+ LP+G+  L+NL  +DLS+N+++  P  +  L  L KL+LS+N++ S+P  +  + NL++LD + N+L++        A + Q++L  N+L   P  LP+  LKE+ + +N I  +  +HL  +  +  L + +NK+  +PEEI +L  L  LDL NND+ +LP SL  + +LK L+++GNP R ++R ++  G + + +YLR R  ++ + K   P     + A        I+   ++    +  S + +A + D++ +++ S PV  +N + N+ +  P ++ +  DS+ D++L  N+++ LP     L  L  +D+  N +  LP  +  +  L    LS+N      P+V+ R+  L+T+++S+  +  I+  ++K L  L  L++ NN I  +PPELG C  +++L LDGN F+ PR AI+S+GT +V+EYLRSRI T
Sbjct:   29 GLLKTARKSGQLNLSGRGLTEVPQSVWRLNLDTPEEAKQNLSF-GADDRWWDQTDLTKLLLSSNKLEALSEDVKLLPALTVLDVHDNQLTSLPTSIGELQHLQKLSLSHNKLKELPEEVWSLKNLTCLQLQQNLLEHLPEGVGLLTNLDDIDLSNNQLTAVPDSLGNLNHLVKLNLSHNKLKSLPSGISVMKNLRLLDCTHNQLESIPPVLSQMASLEQLYLRHNKLRFLP-ELPSSRLKELHVGNNQIEVLEAEHLKHLSTLSVLELRDNKVKSLPEEIKLLQGLERLDLVNNDISSLPASLALLPKLKILTLEGNPLRGIRRDLLTKGTNELLKYLRGRIKEDPDGKGDEP-----DTAMTLPSQAKINVHTIKTLKTLDYSEKQVACVPDDVFDAVGSEPVASVNFSKNQLAAVPPRVVELKDSVSDINLGFNKLTSLPLEFCMLQQLAHIDLRNNLLTSLPMEIEALMKLRSITLSFNRF-KLFPEVLYRVPSLETILISNNQVGAINPLQLKALDKLSTLDLQNNDIMQVPPELGNCTSLRALMLDGNPFRNPRAAIVSRGTDAVLEYLRSRIPT 600          
BLAST of Leucine-rich repeat-containing protein 40 vs. TrEMBL
Match: B5DG62 (Leucine rich repeat containing 40 OS=Salmo salar OX=8030 GN=lrrc2 PE=2 SV=1)

HSP 1 Score: 323.553 bits (828), Expect = 3.138e-98
Identity = 198/580 (34.14%), Postives = 343/580 (59.14%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKS-ISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             LLK A+KSG LNL+ R ++E+P SV+++N+    + K  +SF  +D  WWD   LTKL+L +N +  +S+D+ LL  L+ LD+ DN ++SLP SI  L  L+  +++ NK+++LP ++ +   L  L    N L+ LP+G+  L+NL  +DLS+N+++  P  +  L  L KL+LS+N++ S+P  +  + NL++LD + N+L++        A + Q++L  N+L   P  LP+  LKE+ + +N I  +  +HL  +  +  L + +NK+  +PEEI +L  L  LDL NND+ +LP +L  + +LK L+++GNP R ++R ++  G + + +YLR R  ++ + K   P     + A        I+   ++   I+  S + +A + D++ +++ S PV  +N + N+ +  P ++ +  DS+ D++L  N+++ LP     L  L  +D+  N +  LP  +  +  L    LS+N      P+V+ R+  L+T+++S+  +  I+  ++K L  L  L++ NN I  +PPELG C  +++L LDGN F+ PR AI+S+GT +V+EYLRSRI T
Sbjct:   29 GLLKTARKSGQLNLSGRGLTEVPQSVWRLNLDTPEEAKQNLSF-GADDRWWDQTDLTKLLLPSNKLEALSEDVKLLPALTVLDVHDNQLTSLPTSIGELQHLQKLSLSHNKLKELPKEVWSLKNLTCLQLQQNLLEHLPEGVGLLTNLDDIDLSNNQLTAVPDSLGNLNHLVKLNLSHNKLKSLPSGISVMKNLRLLDCTHNQLESIPPVLSQMASLEQLYLRHNKLRFLP-ELPSSRLKELHVGNNQIEVLEAEHLKHLSTLSVLELRDNKVKTLPEEIELLQGLERLDLVNNDISSLPAALALLPKLKILTLEGNPLRGIRRDLLTKGTNELLKYLRGRIKEDPDGKGDEP-----DTAMTLPSQAKINVHTIKTLKILDYSEKQMACVPDDVFDAVGSEPVASVNFSKNQLAAVPPRLVELKDSVSDINLGFNKLTSLPLEFCMLQQLAHIDLRNNLLTSLPMEIEALMKLRSITLSFNRF-KLFPEVLYRVPSLETILISNNQVGAINPLQLKALDKLSTLDLQNNDIMQVPPELGNCTSLRALMLDGNPFRNPRAAIVSRGTDAVLEYLRSRIPT 600          
BLAST of Leucine-rich repeat-containing protein 40 vs. TrEMBL
Match: A0A060WCC5 (Uncharacterized protein OS=Oncorhynchus mykiss OX=8022 GN=GSONMT00066715001 PE=4 SV=1)

HSP 1 Score: 323.168 bits (827), Expect = 3.239e-98
Identity = 197/580 (33.97%), Postives = 343/580 (59.14%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKS-ISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             LLK A+KSG LNL+ R ++E+P SV+++N+    + K  +SF  +D  WWD   LTKL+L++N +  +S+D+ LL  L+ LD+ DN ++SLP SI  L  L+  +++ NK+++ P++I +   L  L    N L+ LP+G+  L+NL  +DLS+N+++  P  +  L  L KL+LS+N++ S+P  +  + NL++LD + N+L++        A + Q++L  N+L   P  LP+  LKE+ + +N I  +  +HL  +  +  L + +NK+  +PEEI +L  L  LDL NND+ +LP +L  + +LK L+++GNP R ++R ++  G + + +YLR R  ++ + K   P     + A        I+   ++    +  S + +A + D++ +++ S PV  +N + N+ +  P ++ +  DS+ D++L  N+++ LP     L  L  +D+  N +  LP  +  +  L    LS+N      P+V+ R+  L+T+++S+  +  I+  ++K L  L  L++ NN I  +PPELG C  +++L LDGN F+ PR AI+S+GT +V+EYLRSRI T
Sbjct:   29 GLLKTARKSGQLNLSGRGLTEVPQSVWRLNLDTPEEAKQNLSF-GADDRWWDQTDLTKLLLSSNKLEALSEDVKLLPALTVLDVHDNQLTSLPTSIGELQHLQKLSLSHNKLKEFPEEIWSLKNLTCLQLQQNLLEHLPEGVGLLTNLDDIDLSNNQLTAVPDSLGNLNHLVKLNLSHNKLKSLPSGISVMKNLRLLDCTHNQLESIPPVLSQMASLEQLYLRHNKLRFLP-ELPSSRLKELHVGNNQIEVLEAEHLKHLSTLSVLELRDNKVKTLPEEIKLLQGLERLDLVNNDISSLPAALALLPKLKILTLEGNPLRGIRRDLLTKGTNELLKYLRGRIKEDSDGKGDEP-----DTAMTLPSQAKINVHTIKTRKTLDYSEKQMACVPDDVFDAVGSEPVASVNFSKNQLAAVPPRVVELKDSVSDINLGFNKLTSLPLEFCMLQQLAHIDLRNNLLTSLPMEIEALMKLRSITLSFNRF-KLFPEVLYRVPSLETILISNNQVGAINPLQLKALDKLSTLDLQNNDIMQVPPELGNCTSLRALMLDGNPFRNPRAAIVSRGTDAVLEYLRSRIPT 600          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Cavefish
Match: lrrc40 (leucine rich repeat containing 40 [Source:NCBI gene;Acc:103027596])

HSP 1 Score: 303.138 bits (775), Expect = 6.578e-94
Identity = 203/586 (34.64%), Postives = 337/586 (57.51%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINM-PNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQE------EEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             LLK A++SG LNL+ R ++E+P SV+++N+ P    ++++SF  SD  WW+   LTKL+L++N +  +S+D+ LL  L  LDI DN + +LP +I  L QL+  N++ NK+  LP ++ N   L+ L    N L+ LP  L  L  L  +DLS+N++   P  +  L  L KL+LS+N + S+P  +  + NL++LD S+N+L++        A + Q++L  N+L   P +   K LKE+   +N I  +   HL  +  +  L + +NK+  +PEEI++L  L  LDL+NND+ ++P  LG++ +L  L+++GNP R ++R ++  G   + +YLR R  +E      +EPK+          A        I+   ++    ++ S +    + D++ +++    V  +N + N+ +  P +I +  D+L DL+L  N++S +P   S L  L  +D+  N +  LP  L  +  L   ILS+N      PDV+ R+  L+T++MS+  +  ID  ++K+L  L  L++ NN I  +PPELG C  +++L LDGN F+ PR AI++KGT S++EYLRSRI T
Sbjct:   28 GLLKGARQSGQLNLSGRGLTEVPQSVWRLNIDPPEEAQQNVSFSASDR-WWEQTDLTKLLLSSNKLETLSEDVKLLPALVVLDIHDNQLRTLPATIGELEQLQKLNLSHNKMTHLPLELWNLTNLRCLHLQQNLLEQLPSELGQLCQLEDLDLSNNKLIIVPDGLANLNNLVKLNLSFNSLKSLPSAISEMKNLRMLDCSRNQLESVPPVLAQMASLEQLYLRHNKLRFLPELPSCKTLKELHCGNNQIEVLEAAHLKHLSALSVLELRDNKVKSLPEEITLLQGLQRLDLTNNDLSSIPCGLGNLPKLTSLTLEGNPLRTIRRELLTKGTSELLKYLRSRIQEEPDGNLKDEPKT----------AMTLPSQSRINVHAIKTLKTLEYSQKQEVAIPDDVFDAVSDGAVVNVNFSKNQLTEVPPRIVELKDTLADLNLGFNKLSAVPIEFSKLQQLVHVDLRNNLLTSLPMELESLK-LRSIILSFNRF-KAFPDVLYRILSLETILMSNNQVGAIDPLRLKLLDKLSTLDLQNNDIMQVPPELGNCTSLRALMLDGNPFRNPRAAIVAKGTDSLLEYLRSRIPT 600          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Cavefish
Match: lrrc40 (leucine rich repeat containing 40 [Source:NCBI gene;Acc:103027596])

HSP 1 Score: 288.115 bits (736), Expect = 1.921e-88
Identity = 195/586 (33.28%), Postives = 326/586 (55.63%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINM-PNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQE------EEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             LLK A++SG LNL+ R ++E+P SV+++N+ P    ++++SF  SD  WW+   LTKL+L++N +  +S+D+ LL  L  LDI DN + +LP +I  L QL+  N++ NK+  LP ++ N   L+ L    N L+ LP  L  L  L  +DLS+N++   P  +  L  L KL+LS+N + S+P  +  + NL++LD S+N+L++        A + Q++L  N+L   P +   K LKE+   +N I  +   HL  +  +  L + +NK+  +PEEI++L  L  LDL+NND+ ++P  LG++ +L  L+++GNP R ++R ++  G   + +YLR R  +E      +EPK+          A        I+   ++    ++ S +    + D++ +++    V  +N + N+ +  P +I +  D+L DL+L  N++S +P   S L  L  +D+ F                              PDV+ R+  L+T++MS+  +  ID  ++K+L  L  L++ NN I  +PPELG C  +++L LDGN F+ PR AI++KGT S++EYLRSRI T
Sbjct:   28 GLLKGARQSGQLNLSGRGLTEVPQSVWRLNIDPPEEAQQNVSFSASDR-WWEQTDLTKLLLSSNKLETLSEDVKLLPALVVLDIHDNQLRTLPATIGELEQLQKLNLSHNKMTHLPLELWNLTNLRCLHLQQNLLEQLPSELGQLCQLEDLDLSNNKLIIVPDGLANLNNLVKLNLSFNSLKSLPSAISEMKNLRMLDCSRNQLESVPPVLAQMASLEQLYLRHNKLRFLPELPSCKTLKELHCGNNQIEVLEAAHLKHLSALSVLELRDNKVKSLPEEITLLQGLQRLDLTNNDLSSIPCGLGNLPKLTSLTLEGNPLRTIRRELLTKGTSELLKYLRSRIQEEPDGNLKDEPKT----------AMTLPSQSRINVHAIKTLKTLEYSQKQEVAIPDDVFDAVSDGAVVNVNFSKNQLTEVPPRIVELKDTLADLNLGFNKLSAVPIEFSKLQQLVHVDLRF---------------------------KAFPDVLYRILSLETILMSNNQVGAIDPLRLKLLDKLSTLDLQNNDIMQVPPELGNCTSLRALMLDGNPFRNPRAAIVAKGTDSLLEYLRSRIPT 575          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Cavefish
Match: lrrc40 (leucine rich repeat containing 40 [Source:NCBI gene;Acc:103027596])

HSP 1 Score: 286.96 bits (733), Expect = 6.757e-88
Identity = 197/580 (33.97%), Postives = 329/580 (56.72%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINM-PNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVT 1864
             LLK A++SG LNL+ R ++E+P SV+++N+ P    ++++SF  SD  WW+   LTKL+L++N +  +S+D+ LL  L  LDI DN + +LP +I  L QL+  N++ NK+  LP ++ N   L+ L    N L+ LP  L  L  L  +DLS+N++   P  +  L  L KL+LS+N + S+P  +  + NL++LD S+N+L++        A + Q++L  N+L   P +   K LKE+   +N I  +   HL  +  +  L + +NK+  +PEEI++L  L  LDL+NND+ ++P  LG++ +L  L+++GNP R ++R ++                 ++EPK+          A        I+   ++    ++ S +    + D++ +++    V  +N + N+ +  P +I +  D+L DL+L  N++S +P   S L  L  +D+  N +  LP  L  +  L   ILS+N      PDV+ R+  L+T++MS+  +  ID  ++K+L  L  L++ NN I  +PPELG C  +++L LDGN F+ PR AI++KGT S++EYLRSRI T
Sbjct:   28 GLLKGARQSGQLNLSGRGLTEVPQSVWRLNIDPPEEAQQNVSFSASDR-WWEQTDLTKLLLSSNKLETLSEDVKLLPALVVLDIHDNQLRTLPATIGELEQLQKLNLSHNKMTHLPLELWNLTNLRCLHLQQNLLEQLPSELGQLCQLEDLDLSNNKLIIVPDGLANLNNLVKLNLSFNSLKSLPSAISEMKNLRMLDCSRNQLESVPPVLAQMASLEQLYLRHNKLRFLPELPSCKTLKELHCGNNQIEVLEAAHLKHLSALSVLELRDNKVKSLPEEITLLQGLQRLDLTNNDLSSIPCGLGNLPKLTSLTLEGNPLRTIRRELLTVKEPD--------GNLKDEPKT----------AMTLPSQSRINVHAIKTLKTLEYSQKQEVAIPDDVFDAVSDGAVVNVNFSKNQLTEVPPRIVELKDTLADLNLGFNKLSAVPIEFSKLQQLVHVDLRNNLLTSLPMELESLK-LRSIILSFNRF-KAFPDVLYRILSLETILMSNNQVGAIDPLRLKLLDKLSTLDLQNNDIMQVPPELGNCTSLRALMLDGNPFRNPRAAIVAKGTDSLLEYLRSRIPT 586          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Cavefish
Match: shoc2 (SHOC2 leucine rich repeat scaffold protein [Source:NCBI gene;Acc:555476])

HSP 1 Score: 121.709 bits (304), Expect = 9.644e-29
Identity = 142/511 (27.79%), Postives = 250/511 (48.92%), Query Frame = 2
Query:  368 SHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIPVK--------GINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGL--TIIDY--EKIKMLSNLEVLXXXXXXXXXXPP-ELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLR 1849
            + LD+S  +I  LP SI  LTQL    +  NK+Q LP ++     L TL+ S N+L SLP  L+ L  L ++DL HN++ E P  +  +  LT L L +N+IT++   +  L  L +L + +NK++           Q+   +  L          NL  + + HN +  + K+ +     I  L + +N++ D+PE I  L+S++ L L  N + A+P SL    +L+ L+++ N   +L   +++S  +     L  RN  +  P   GP  Q     ++  +   I++       RA  + KL+ ++         N L S+P+          +NL  N+ +  P  I   + SL+ L LSNN + +LP+ I +L  LR LD+  NK+  LP  ++ +  L   +L+ N +  T+P  +  +  L     +H GL   ++ +  E+I  L NLE L +++N   +  P EL LC K+  ++++        P I++ G + ++++L+
Sbjct:   55 TRLDLSKRSIHLLPSSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVTSLTTLYLRFNRITTVEKDIRNLAKLTMLSIRENKIK-----------QLPAEIGELC---------NLITLDVAHNQLEHLPKE-IGNCTQITNLDLQHNELLDLPETIGNLSSINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTL-ARNCFQSYPVG-GPS-QFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKD---------NQLTSLPLDFGTWTSMVELNLATNQLTKIPEDICGLA-SLEVLILSNNLLKKLPHGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQL-TTLPRGIGHLTNL-----THLGLGENLLQHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLK 525          

HSP 2 Score: 114.005 bits (284), Expect = 3.605e-26
Identity = 127/471 (26.96%), Postives = 228/471 (48.41%), Query Frame = 2
Query:  272 SSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQ-EEEPKSFG--PGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSL-HSI----PVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLT 1651
            SS  +   LT+L L +N +  +  ++  L  L  L +S+N+++SLPDS+ NL +L+  ++  NK++++P  +     L TL   +N + ++ K +  L+ LT++ +  N+I + P +I EL  L  LD+++NQ+  +P  +     +  LDL  N+L    E  G  + ++++ L  NRL+  P  L   + L+E++L +N IS + +  LS + N+ +LT+A N     P                + + +L     +ME  +   I+  PF +  R+ + S        L M++ Q    P  FG    +  LN AT        +Q       I  L+   +  LS+ +L  L H I     ++ ++L  NK    P +I    D LQ L L+NNQ++ LP  I  L+ L  L +  N ++ LPE +  +  L    L+ N   +++P  ++  + L  + + +C L+
Sbjct:   69 SSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVTSLTTLYLRFNRITTVEKDIRNLAKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPETIGNLSSINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTLARNCFQSYP---------VGGPSQFSTIYSL-----NMEHNR---INKIPFGIFSRAKVLSK-------LNMKDNQLTSLPLDFGTWTSMVELNLAT--------NQLTKIPEDICGLASLEVLILSNNLLKKLPHGIGNLRKLRELDLEENKLESLPNEIAYLKD-LQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLQHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLS 506          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Cavefish
Match: shoc2 (SHOC2 leucine rich repeat scaffold protein [Source:NCBI gene;Acc:555476])

HSP 1 Score: 122.094 bits (305), Expect = 9.826e-29
Identity = 141/509 (27.70%), Postives = 249/509 (48.92%), Query Frame = 2
Query:  368 SHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIPVK--------GINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDY--EKIKMLSNLEVLXXXXXXXXXXPP-ELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLR 1849
            + LD+S  +I  LP SI  LTQL    +  NK+Q LP ++     L TL+ S N+L SLP  L+ L  L ++DL HN++ E P  +  +  LT L L +N+IT++   +  L  L +L + +NK++           Q+   +  L          NL  + + HN +  + K+ +     I  L + +N++ D+PE I  L+S++ L L  N + A+P SL    +L+ L+++ N   +L   +++S  +     L  RN  +  P   GP  Q     ++  +   I++       RA  + KL+ ++         N L S+P+          +NL  N+ +  P  I   + SL+ L LSNN + +LP+ I +L  LR LD+  NK+  LP  ++ +  L   +L+ N +  T+P  +  +  L  L +   G  ++ +  E+I  L NLE L +++N   +  P EL LC K+  ++++        P I++ G + ++++L+
Sbjct:   86 TRLDLSKRSIHLLPSSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVTSLTTLYLRFNRITTVEKDIRNLAKLTMLSIRENKIK-----------QLPAEIGELC---------NLITLDVAHNQLEHLPKE-IGNCTQITNLDLQHNELLDLPETIGNLSSINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTL-ARNCFQSYPVG-GPS-QFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKD---------NQLTSLPLDFGTWTSMVELNLATNQLTKIPEDICGLA-SLEVLILSNNLLKKLPHGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQL-TTLPRGIGHLTNLTHLGL---GENLLQHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLK 556          

HSP 2 Score: 114.39 bits (285), Expect = 2.636e-26
Identity = 127/471 (26.96%), Postives = 228/471 (48.41%), Query Frame = 2
Query:  272 SSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQ-EEEPKSFG--PGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSL-HSI----PVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLT 1651
            SS  +   LT+L L +N +  +  ++  L  L  L +S+N+++SLPDS+ NL +L+  ++  NK++++P  +     L TL   +N + ++ K +  L+ LT++ +  N+I + P +I EL  L  LD+++NQ+  +P  +     +  LDL  N+L    E  G  + ++++ L  NRL+  P  L   + L+E++L +N IS + +  LS + N+ +LT+A N     P                + + +L     +ME  +   I+  PF +  R+ + S        L M++ Q    P  FG    +  LN AT        +Q       I  L+   +  LS+ +L  L H I     ++ ++L  NK    P +I    D LQ L L+NNQ++ LP  I  L+ L  L +  N ++ LPE +  +  L    L+ N   +++P  ++  + L  + + +C L+
Sbjct:  100 SSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVTSLTTLYLRFNRITTVEKDIRNLAKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPETIGNLSSINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTLARNCFQSYP---------VGGPSQFSTIYSL-----NMEHNR---INKIPFGIFSRAKVLS-------KLNMKDNQLTSLPLDFGTWTSMVELNLAT--------NQLTKIPEDICGLASLEVLILSNNLLKKLPHGIGNLRKLRELDLEENKLESLPNEIAYLKD-LQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLQHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLS 537          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Sea Lamprey
Match: lrrc40 (leucine rich repeat containing 40 [Source:NCBI gene;Acc:334130])

HSP 1 Score: 312.383 bits (799), Expect = 4.696e-98
Identity = 195/581 (33.56%), Postives = 329/581 (56.63%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISE--IPNSVYKINM-PNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRI 1858
            + LL+ A+ SG LNLA R + E  +P +V++IN+ P     + + F  S   WW+   LTKLIL +N +  +S D+ LL  L+ LD+ DN ++ LP  +  L  L+  N++ NK+Q LP+ +     L +L   +N L+ +   +  L+ L  +DLS N ++  P  + +L  +TKL+++ N++  +P  ++ +  L  L+ + N L++     G  A + Q++L  NRL   P +     LKE+ + +N ISE+  +HL  +  I  L + +NK+ ++P+E+++L  L  LDL+NND+ +LP +LG++ +LK L+++GNP R ++R IIN G   I ++LR R    EEP         +   T+    G I+   + A   +  S +  AD+ DE+  ++    V  ++ + N+ S  P +I +  D + D+++  N+IS L   +  L  L  LD+  N +  LP  +  +S L   I+S N     IP V+ R+  L+TL+ S   + ++D   ++ L  L  L++ NN I+ +PP+LGLC  ++SL L GN F+ PRPA++SKGTA+++EYLR RI
Sbjct:   28 QGLLRAARTSGQLNLAGRGLGEGSVPLAVWRINVDPPEEVARGVVFGASGERWWEQADLTKLILASNRLRALSDDLQLLPALTVLDVHDNQLTELPQVLGELVNLQKLNVSHNKLQTLPESLWAISSLLSLHVEHNELEGISNNIGNLARLEELDLSSNRLTALPGTLGKLTRVTKLNVAENKLRELPTEIKSMKGLCQLEATHNLLESVPAALGGMASLQQLYLRHNRLKSLPELHNCAALKELHVGNNQISELGPEHLRPLGAISVLDLRDNKLKELPDEVTLLHGLERLDLTNNDISSLPNALGNLGKLKSLALEGNPLRAIRRDIINRGTQEILKFLRSRI---EEPTGSEDSPDTVTAMTLPSQGG-INAFTISAQKALHYSGKKAADIPDEVFEAIRGSTVTAVDFSKNQLSTIPPRIVELKDMVTDVNVGFNKISVLSLELCMLGNLTHLDLRNNALSSLPNEMEALSRLQSIIISCNRF-REIPPVLYRVGTLETLLASDNQIGVVDATGLRSLERLGTLDLQNNDITVVPPQLGLCVSLRSLLLGGNRFRSPRPALLSKGTATLLEYLRDRI 603          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004940.1 (pep scaffold:Pmarinus_7.0:GL476356:339323:347865:-1 gene:ENSPMAG00000004448.1 transcript:ENSPMAT00000004940.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 105.916 bits (263), Expect = 2.705e-24
Identity = 127/530 (23.96%), Postives = 247/530 (46.60%), Query Frame = 2
Query:  368 SHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIPVK--------GINLNGNKFSIFP--------LKIFQFSDSL--------------QDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNC--FKVPRPAIISKGTASVMEYLR 1849
            + LD++  +I+SLP +I  LTQL    +  N++  LP +I   + L TL+ + N+L  LP  L  L++L ++DL HN++   PP +  L  LT L L +N+IT +   +  L  L +L + +NK++       A + ++                ++L  + + HN +  + ++ +     +  L + +N++ D+P+ I  L SL+ L L  N + A+P +L +  +L+ L+++ N    L   +++S   ++      RN  +  P   GP  Q     ++  +   I +       RA  + KL+ ++         N L S+P+          +NL  N+ +  P        L+I   S++L              ++LDL  N++  LPN I+ L  L++L ++ N++  LP  +  +  L+H ++  N + + +P+ +  +  L+ L ++       D   +  L                P EL LC K+  ++++ NC   ++P P I+S G + +++YL+
Sbjct:   52 TRLDLAKRSIASLPPNIKELTQLTELYLYGNRLPCLPTEIGCLVNLVTLALNENSLTGLPDTLTGLTSLRMLDLRHNKLRSIPPVVYRLTSLTVLYLRFNRITQVEKDIGNLSKLTMLSVRENKIKLLP----AEIGEL----------------RSLLTLDVAHNQLEHLPEE-IGNCVQVTNLDLQHNELLDLPDSIGNLASLNRLGLRYNRLSAVPTTLANCTELEDLNLENNNISTLPEGLLSS-LVNLSSLTLARNCFQAYPVG-GPS-QFTTVYSLNMEHNHIGKIPFGIFSRAKALSKLNMKD---------NQLTSLPLDIGTWKSMVELNLATNQLTKIPDDISELTSLEILVLSNNLLRKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTSLPRGIGHLCSLTHLMVGENQLTH-VPEEIGTLENLEELYLN-------DNPNLHNL----------------PFELALCSKLLIMSIE-NCPLSQLPGP-IVSSGPSFIIQYLK 522          

HSP 2 Score: 97.0561 bits (240), Expect = 1.766e-21
Identity = 122/466 (26.18%), Postives = 211/466 (45.28%), Query Frame = 2
Query:  299 TKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXX-MKALPLSLGDMEQLKC---LSIDGN-----PFRMLKRSIINSGADSIKRYLRMRNTQEEE-PKSFGP--GLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLT 1651
            T+L L   SI+ +  +I  L +L+ L +  N +  LP  I  L  L    +N+N +  LPD +     L+ L   +N L+S+P  +  L++LT++ L  N I++    I  L  LT L +  N+I  +P  +  L +L  LD++ N+L+   E  G C  V  + L  N L   P  + N  +L  + L +N +S +    L+    +  L + NN I+ +PE +       +      +  +A P+  G   Q      L+++ N     PF +  R      A ++ + L M++ Q    P   G    +  LN AT +      D ++L +  I+ LS   L  L   + N      ++ ++L  NK    P +I    D LQ L L+NNQ++ LP  I  L  L  L +  N++  +PE +  +  L    L+ N   + +P  ++  + L  + + +C L+
Sbjct:   52 TRLDLAKRSIASLPPNIKELTQLTELYLYGNRLPCLPTEIGCLVNLVTLALNENSLTGLPDTLTGLTSLRMLDLRHNKLRSIPPVVYRLTSLTVLYLRFNRITQVEKDIGNLSKLTMLSVRENKIKLLPAEIGELRSLLTLDVAHNQLEHLPEEIGNCVQVTNLDLQHNELLDLPDSIGNLASLNRLGLRYNRLSAVPTT-LANCTELEDLNLENNNISTLPEGLLSSLVNLSSLTLARNCFQAYPV--GGPSQFTTVYSLNMEHNHIGKIPFGIFSR------AKALSK-LNMKDNQLTSLPLDIGTWKSMVELNLATNQLTKIPDDISELTSLEILVLSNNLLRKLPHGLGNLRK---LRELDLEENKLESLPNEIAYLKD-LQKLVLTNNQLTSLPRGIGHLCSLTHLMVGENQLTHVPEEIGTLENLEELYLNDNPNLHNLPFELALCSKLLIMSIENCPLS 503          

HSP 3 Score: 92.4337 bits (228), Expect = 6.892e-20
Identity = 87/297 (29.29%), Postives = 147/297 (49.49%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHV---NRLTKFPIVLPNK--NLKEISLTHNMISEI---------------TKD-HLSKIP-------NICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSI 1102
            L  L L  N +  I   +  L  L+ L +  N I+ +   I NL++L   ++ +NKI+ LP +I     L TL  ++N L+ LP+ +     +T +DL HNE+ + P  I  L  L +L L YN+++++P TL     L+ L+L  N + T  EG  + +  +       N    +P+  P++   +  +++ HN I +I                KD  L+ +P       ++  L +A N++  IP++IS LTSL  L LSNN ++ LP  LG++ +L+ L ++ N    L   I
Sbjct:  120 LRMLDLRHNKLRSIPPVVYRLTSLTVLYLRFNRITQVEKDIGNLSKLTMLSVRENKIKLLPAEIGELRSLLTLDVAHNQLEHLPEEIGNCVQVTNLDLQHNELLDLPDSIGNLASLNRLGLRYNRLSAVPTTLANCTELEDLNLENNNISTLPEGLLSSLVNLSSLTLARNCFQAYPVGGPSQFTTVYSLNMEHNHIGKIPFGIFSRAKALSKLNMKDNQLTSLPLDIGTWKSMVELNLATNQLTKIPDDISELTSLEILVLSNNLLRKLPHGLGNLRKLRELDLEENKLESLPNEI 416          

HSP 4 Score: 89.7373 bits (221), Expect = 3.901e-19
Identity = 72/266 (27.07%), Postives = 133/266 (50.00%), Query Frame = 2
Query:   95 IGNSESQNNKAFENLLKQAKKSGS-LNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEI 880
            I   +S N +  + L K  +++ + L+LA R+I+ +P        PN+ +                  LT+L L  N +  +  +I  L  L  L +++N+++ LPD++T LT L+  ++  NK++ +P  +     L  L   +N +  + K +  LS LT++ +  N+I   P +I EL  L  LD+++NQ+  +P  +     +  LDL  N+L    +  G  A ++++ L  NRL+  P  L N   L++++L +N IS +
Sbjct:   29 IPRKKSSNMEVVKELNKCKEQNATRLDLAKRSIASLP--------PNIKELTQ---------------LTELYLYGNRLPCLPTEIGCLVNLVTLALNENSLTGLPDTLTGLTSLRMLDLRHNKLRSIPPVVYRLTSLTVLYLRFNRITQVEKDIGNLSKLTMLSVRENKIKLLPAEIGELRSLLTLDVAHNQLEHLPEEIGNCVQVTNLDLQHNELLDLPDSIGNLASLNRLGLRYNRLSAVPTTLANCTELEDLNLENNNISTL 271          

HSP 5 Score: 74.3294 bits (181), Expect = 3.115e-14
Identity = 67/216 (31.02%), Postives = 103/216 (47.69%), Query Frame = 2
Query:  167 LNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLT--KLILTANSISFISKDI-SLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVN 799
            LNL N NIS +P  +    +   +   + +  Q+        F T   L +  N I  I   I S    LS L++ DN ++SLP  I     +   N+  N++ K+PD I     L+ L  S N L+ LP GL  L  L  +DL  N++   P +I  L  L KL L+ NQ+TS+P  +  L +L  L + +N+L    E  G    + +++L+ N
Sbjct:  261 LNLENNNISTLPEGLLSSLVNLSSLTLARNCFQAYPVGGPSQFTTVYSLNMEHNHIGKIPFGIFSRAKALSKLNMKDNQLTSLPLDIGTWKSMVELNLATNQLTKIPDDISELTSLEILVLSNNLLRKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTSLPRGIGHLCSLTHLMVGENQLTHVPEEIGTLENLEELYLNDN 476          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Sea Lamprey
Match: scrib (scribble planar cell polarity protein [Source:NCBI gene;Acc:368473])

HSP 1 Score: 98.2117 bits (243), Expect = 1.671e-21
Identity = 86/282 (30.50%), Postives = 135/282 (47.87%), Query Frame = 2
Query:  290 VFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSI 1126
            + L  L ++ N I+ I   I L   L  +D S N ++ LP+  T L  L Y ++N   +Q LPD I N   L TL    N LK+LP  L+ L  L  +DL +NE+   P  +  L  + +L L  NQ+ ++P  +  L  L  LD+SQN+L+   +  G  A +       N L + P  L   K+L  +    N ++ +  + +    N+  L +  N++  +P  I  LT L+NL+L  N + ++P  +G    L  LS+  N    +   I  SGA  I
Sbjct:   29 MHLVDLDMSRNDIAEIPDSIKLCTCLEVVDFSGNPLTRLPEGFTQLKSLIYLSLNDVSLQGLPDDIGNLSNLVTLELRENLLKTLPTSLHLLVKLEQLDLGNNELETLPGSLGSLPNVRELWLDGNQLEALPSEIGELRRLVCLDISQNRLERLPDAIGGLAALTDFLASQNHLEELPEELGKLKHLSILKADQNRLTHLP-EAIGDCENLTELILTENQLVTLPASIGKLTKLTNLNLDKNRLNSIPPEIGGCGALNVLSLRDNRLTQVPGEI--SGASQI 307          

HSP 2 Score: 88.5817 bits (218), Expect = 1.857e-18
Identity = 78/259 (30.12%), Postives = 124/259 (47.88%), Query Frame = 2
Query:  356 LDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTF--SEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMIS-EITKDHLSKIPN----ICTLT---IANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSI 1102
            L  L  L +SDN +  LP  I N   L   ++++N I ++PD I+    L+ +  S N L  LP+G   L +L  + L+   +   P  I  L  L  L+L  N + ++P +L  L  L+ LDL  N+L+T   S G    V ++WL  N+L   P         EI     ++  +I+++ L ++P+    +  LT    + N + ++PEE+  L  LS L    N +  LP ++GD E L  L +  N    L  SI
Sbjct:    5 LHNLRKLGLSDNELQRLPPDIANFMHLVDLDMSRNDIAEIPDSIKLCTCLEVVDFSGNPLTRLPEGFTQLKSLIYLSLNDVSLQGLPDDIGNLSNLVTLELRENLLKTLPTSLHLLVKLEQLDLGNNELETLPGSLGSLPNVRELWLDGNQLEALP--------SEIGELRRLVCLDISQNRLERLPDAIGGLAALTDFLASQNHLEELPEELGKLKHLSILKADQNRLTHLPEAIGDCENLTELILTENQLVTLPASI 255          

HSP 3 Score: 86.2705 bits (212), Expect = 1.035e-17
Identity = 61/231 (26.41%), Postives = 110/231 (47.62%), Query Frame = 2
Query:  290 VFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILT 976
            V L +L L  N +  +   +  L  +  L +  N + +LP  I  L +L   +I++N++++LPD I     L     S N L+ LP+ L  L +L+I+    N ++  P  I +   LT+L L+ NQ+ ++P ++ +L  L  L+L +N+L +     G C  ++ + L  NRLT+ P                         +S    I  L +A N++ ++P E++ L+
Sbjct:  121 VKLEQLDLGNNELETLPGSLGSLPNVRELWLDGNQLEALPSEIGELRRLVCLDISQNRLERLPDAIGGLAALTDFLASQNHLEELPEELGKLKHLSILKADQNRLTHLPEAIGDCENLTELILTENQLVTLPASIGKLTKLTNLNLDKNRLNSIPPEIGGCGALNVLSLRDNRLTQVP-----------------------GEISGASQIHVLDLAGNRLENLPIELAKLS 328          

HSP 4 Score: 57.3806 bits (137), Expect = 8.193e-9
Identity = 36/121 (29.75%), Postives = 65/121 (53.72%), Query Frame = 2
Query:  320 NSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSM 682
            N ++ + + I   + L+ L +++N + +LP SI  LT+L   N++KN++  +P +I     L  LS   N L  +P  ++  S + ++DL+ N +   P ++ +L  L  L LS NQ   M
Sbjct:  223 NRLTHLPEAIGDCENLTELILTENQLVTLPASIGKLTKLTNLNLDKNRLNSIPPEIGGCGALNVLSLRDNRLTQVPGEISGASQIHVLDLAGNRLENLPIELAKLS-LKALWLSENQSQPM 342          

HSP 5 Score: 56.225 bits (134), Expect = 2.307e-8
Identity = 87/361 (24.10%), Postives = 154/361 (42.66%), Query Frame = 2
Query:  836 NLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKR--YLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHS-IPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIV-TN*RVSIESLIQFLD 1906
            NL+++ L+ N +  +  D ++   ++  L ++ N IA+IP+ I + T                        L+ +   GNP   L       G   +K   YL + +            LQ L      DD G +       + +V L  R   +L   +  SLH  + ++ ++L  N+    P  +    + +++L L  NQ+  LP+ I  L  L  LDIS N++  LP+++  ++ L+ F+ S N +   +P+ + ++ +L  L      LT +  E I    NL  L ++ N +  +P  +G   K+ +LNLD N      P I   G  +V+    +R+      +S  S I  LD
Sbjct:    7 NLRKLGLSDNELQRLPPD-IANFMHLVDLDMSRNDIAEIPDSIKLCTC-----------------------LEVVDFSGNPLTRLP-----EGFTQLKSLIYLSLNDVS----------LQGL-----PDDIGNL-------SNLVTLELRE--NLLKTLPTSLHLLVKLEQLDLGNNELETLPGSLGSLPN-VRELWLDGNQLEALPSEIGELRRLVCLDISQNRLERLPDAIGGLAALTDFLASQNHL-EELPEELGKLKHLSILKADQNRLTHLP-EAIGDCENLTELILTENQLVTLPASIGKLTKLTNLNLDKNRLNSIPPEIGGCGALNVLSLRDNRLTQVPGEISGASQIHVLD 311          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008655.1 (pep scaffold:Pmarinus_7.0:GL484079:6946:12214:1 gene:ENSPMAG00000007829.1 transcript:ENSPMAT00000008655.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.411 bits (189), Expect = 2.650e-16
Identity = 49/147 (33.33%), Postives = 81/147 (55.10%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQN 736
            L ++ L  N I  + K++  L  L  L ++DN+++SLP +I  L  L+  + ++N+++ +PD I +  +L  ++ S NTL  LP GL  L +LT + LS   +   P  +  L  L  L+L  N + S+P  + RL  L+ LDL  N
Sbjct:   50 LQEIHLDGNYIQELPKELCALPLLRVLSVADNDLASLPPAIGGLAGLRRIDASRNELRDIPDNIRSCRQLSVVNVSNNTLSRLPDGLTQLVSLTELYLSDVLLEFLPASLGRLCKLRVLELRDNHLNSLPKAMHRLSQLRRLDLGCN 196          

HSP 2 Score: 68.5514 bits (166), Expect = 2.686e-13
Identity = 45/150 (30.00%), Postives = 74/150 (49.33%), Query Frame = 2
Query:  293 FLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKL 742
             L  L +  N ++ +   I  L  L  +D S N +  +PD+I +  QL   N++ N + +LPD +   + L  L  S   L+ LP  L  L  L +++L  N ++  P  ++ L  L +LDL  N  + +P  L++L  LQ L +  N L
Sbjct:   72 LLRVLSVADNDLASLPPAIGGLAGLRRIDASRNELRDIPDNIRSCRQLSVVNVSNNTLSRLPDGLTQLVSLTELYLSDVLLEFLPASLGRLCKLRVLELRDNHLNSLPKAMHRLSQLRRLDLGCNDFSHVPPVLQQLTTLQELLMDGNSL 221          

HSP 3 Score: 62.003 bits (149), Expect = 4.139e-11
Identity = 49/206 (23.79%), Postives = 91/206 (44.17%), Query Frame = 2
Query:   68 SNDNSLFIDIGNSESQNNKAFENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMP 685
             +D SL +D+ ++              A+    ++L    I E+P  +  + +  V             +      L ++  + N +  I  +I    +LS +++S+N +S LPD +T L  L    ++   ++ LP  +    +L+ L    N L SLPK ++ LS L  +DL  N+ S  PP + +L  L +L +  N +  +P
Sbjct:   20 GDDGSLILDLSHTRLHTVPPQVYTPASAQSLQEIHLDGNYIQELPKELCALPLLRVLSVADNDLASLPPAIGGLAGLRRIDASRNELRDIPDNIRSCRQLSVVNVSNNTLSRLPDGLTQLVSLTELYLSDVLLEFLPASLGRLCKLRVLELRDNHLNSLPKAMHRLSQLRRLDLGCNDFSHVPPVLQQLTTLQELLMDGNSLLILP 225          

HSP 4 Score: 51.6026 bits (122), Expect = 1.199e-7
Identity = 47/175 (26.86%), Postives = 83/175 (47.43%), Query Frame = 2
Query:  374 LDISDNNISSLPDSI---TNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTF--SEGFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEI 880
            LD+S   + ++P  +    +   L+  +++ N IQ+LP ++     L+ LS + N L SLP  +  L+ L  +D S NE+ + P  I     L+ +++S N ++ +P  L +L +L  L LS   L+    S G    +  + L  N L   P  +     L+ + L  N  S +
Sbjct:   27 LDLSHTRLHTVPPQVYTPASAQSLQEIHLDGNYIQELPKELCALPLLRVLSVADNDLASLPPAIGGLAGLRRIDASRNELRDIPDNIRSCRQLSVVNVSNNTLSRLPDGLTQLVSLTELYLSDVLLEFLPASLGRLCKLRVLELRDNHLNSLPKAMHRLSQLRRLDLGCNDFSHV 201          

HSP 5 Score: 48.1358 bits (113), Expect = 1.890e-6
Identity = 45/176 (25.57%), Postives = 92/176 (52.27%), Query Frame = 2
Query: 1262 IVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCF 1789
            I+ LS   L  +  ++     +  ++ I+L+GN     P ++      L+ L +++N ++ LP  I  L+GLRR+D S N++R +P+++     LS   +S N + + +PD ++++  L  L +S   L  +    +  L  L VL + +N ++++P  +    +++ L+L  N F
Sbjct:   26 ILDLSHTRLHTVPPQVYTPASAQSLQEIHLDGNYIQELPKELCALP-LLRVLSVADNDLASLPPAIGGLAGLRRIDASRNELRDIPDNIRSCRQLSVVNVSNNTL-SRLPDGLTQLVSLTELYLSDVLLEFLP-ASLGRLCKLRVLELRDNHLNSLPKAMHRLSQLRRLDLGCNDF 198          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Sea Lamprey
Match: lrch3 (leucine-rich repeats and calponin homology (CH) domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-071004-44])

HSP 1 Score: 75.0998 bits (183), Expect = 5.658e-15
Identity = 52/151 (34.44%), Postives = 81/151 (53.64%), Query Frame = 2
Query:  311 LTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGF 763
            L+ N ++ +  ++     L  L +  N I S+P++I NL  L Y NI++N++  LP  +   L LQ L+ S N L SLP+ L  L  L+ +D+S NEI   PPQ+  L  L  L++  N +  +P  +  L  +Q LD+S N+L      F
Sbjct:    5 LSKNRLNEVPLEVCHFVSLESLVLYHNCIRSIPEAIVNLRSLTYLNISRNQLTTLPPYL-CKLPLQVLNASNNKLVSLPEELGQLKELSALDVSCNEIQALPPQVASLTCLRDLNVRRNNLVILPDEIADLPLVQ-LDVSCNRLGEIPVSF 153          

HSP 2 Score: 64.6994 bits (156), Expect = 1.462e-11
Identity = 54/233 (23.18%), Postives = 113/233 (48.50%), Query Frame = 2
Query:  446 NINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRM 1144
            +++KN++ ++P ++ +++ L++L   +N ++S+P+ +  L +LT +++S N+++  PP + +L L   L+ S N++ S+P  L +L  L  LD+S N++Q                       P V     L+++++  N +  I  D ++ +P +  L ++ N++ +I                       P+S   ++QL+ L +D NP +     I   G   I +YL M
Sbjct:    4 DLSKNRLNEVPLEVCHFVSLESLVLYHNCIRSIPEAIVNLRSLTYLNISRNQLTTLPPYLCKLPLQV-LNASNNKLVSLPEELGQLKELSALDVSCNEIQALP--------------------PQVASLTCLRDLNVRRNNLV-ILPDEIADLP-LVQLDVSCNRLGEI-----------------------PVSFRKLKQLQSLVLDNNPMKSPPAQICIKGKHHIFKYLHM 190          

HSP 3 Score: 50.8322 bits (120), Expect = 5.438e-7
Identity = 48/187 (25.67%), Postives = 80/187 (42.78%), Query Frame = 2
Query: 1313 NSLHSIPVKGINLNG--------NKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLV-MSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYL 1846
            N + SIP   +NL          N+ +  P  + +    LQ L+ SNN++  LP  +  L  L  LD+S N+I+ LP  ++ ++CL    +  N++   +PD ++ +  +Q  V  +  G   + + K+K L                          +SL LD N  K P   I  KG   + +YL
Sbjct:   31 NCIRSIPEAIVNLRSLTYLNISRNQLTTLPPYLCKLP--LQVLNASNNKLVSLPEELGQLKELSALDVSCNEIQALPPQVASLTCLRDLNVRRNNLV-ILPDEIADLPLVQLDVSCNRLGEIPVSFRKLKQL--------------------------QSLVLDNNPMKSPPAQICIKGKHHIFKYL 188          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Yeast
Match: CYR1 (Adenylate cyclase; required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation [Source:SGD;Acc:S000003542])

HSP 1 Score: 92.4337 bits (228), Expect = 1.008e-19
Identity = 117/450 (26.00%), Postives = 196/450 (43.56%), Query Frame = 2
Query:  326 ISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNK------------LQTFSEGF---------CAPVHQIWLHVNRLTKFPIVLPN---------------------KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPK-----SFGPGLQALNRATIKDDSGFIDQ--------TDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIR 1510
            + FI   I LL     L + +   S  P +IT   +L    + +N I+K+P+ I     L  L+   N L+SLP G   L NL ++DLS N+   +P  IN    L ++DLSYN+I S+P + + L  L  ++LS NK            L+T +  +          + +  ++L  NR++ F   LP                      KN+  ++L    +S I  + L+K+  +  L +  N +  +P+EIS LT L  L ++ N ++ +P  L  ++ L+ L +  N  R     + N    S+            E       S+G  L       I  D+ F D          +L+   ++ LS+ N +D+S   L S     +  + L+GNK +           SL+ L L++NQ+  LP  +S+LS L   D+  N+++
Sbjct:  833 LEFIESSIKLLS----LRMVNIRASKFPSNITKAYKLVSLELQRNFIRKVPNSIMKLSNLTILNLQCNELESLPAGFVELKNLQLLDLSSNKFMHYPEVINYCTNLLQIDLSYNKIQSLPQSTKYLVKLAKMNLSHNKLNFIGDLSEMTDLRTLNLRYNRISSIKTNASNLQNLFLTDNRISNFEDTLPKLRALEIQENPITSISFKDFYPKNMTSLTLNKAQLSSIPGELLTKLSFLEKLELNQNNLTRLPQEISKLTKLVFLSVARNKLEYIPPELSQLKSLRTLDLHSNNIRDFVDGMENLELTSLNISSNAFGNSSLENSFYHNMSYGSKLSKSLMFFIAADNQFDDAMWPLFNCFVNLK---VLNLSYNNFSDVSHMKLES-----ITELYLSGNKLTTLSGDTVLKWSSLKTLMLNSNQMLSLPAELSNLSQLSVFDVGANQLK 1270          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Yeast
Match: CCR4 (Component of the CCR4-NOT transcriptional complex; CCR4-NOT is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening [Source:SGD;Acc:S000000019])

HSP 1 Score: 54.6842 bits (130), Expect = 4.035e-8
Identity = 35/108 (32.41%), Postives = 55/108 (50.93%), Query Frame = 2
Query:  422 NLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQ 745
            +L+ L+ FNI+ N        I  Y  L  L  + N+L  LP  +  LSNL ++DLSHN ++  P ++   + L       N +T++P+    L NLQ L +  N L+
Sbjct:  340 DLSNLQIFNISAN--------IFKYDFLTRLYLNGNSLTELPAEIKNLSNLRVLDLSHNRLTSLPAELGSCFQLKYFYFFDNMVTTLPWEFGNLCNLQFLGVEGNPLE 439          

HSP 2 Score: 52.373 bits (124), Expect = 1.884e-7
Identity = 31/82 (37.80%), Postives = 44/82 (53.66%), Query Frame = 2
Query:  293 FLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLK 538
            FLT+L L  NS++ +  +I  L  L  LD+S N ++SLP  + +  QLKYF    N +  LP +  N   LQ L    N L+
Sbjct:  358 FLTRLYLNGNSLTELPAEIKNLSNLRVLDLSHNRLTSLPAELGSCFQLKYFYFFDNMVTTLPWEFGNLCNLQFLGVEGNPLE 439          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Yeast
Match: SOG2 (Key component of the RAM signaling network; required for proper cell morphogenesis and cell separation after mitosis [Source:SGD;Acc:S000005880])

HSP 1 Score: 48.1358 bits (113), Expect = 3.737e-6
Identity = 45/153 (29.41%), Postives = 77/153 (50.33%), Query Frame = 2
Query:  299 TKLILTANSISFIS-KDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYL--LTKLDLSYNQITSMP--FTLERLHNLQILDLSQNKL 742
            T L L A +I  IS +D+  +  +  L +  N+++SLP S   L++L+Y +++ N  +++P     Y+           L   P+       L I+DLS NEI   P +I+  +   +  L L  N +TS+    ++ +L+ L ILDL  NK+
Sbjct:   45 TTLKLIALNIKSISDEDVGYIQNVERLSLRKNHLTSLPASFKRLSRLQYLDLHNNNFKEIP-----YI-----------LTQCPQ-------LEILDLSSNEIEALPDEISSFWQDNIRVLSLKDNNVTSIRNLKSITKLNKLSILDLEDNKI 174          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Nematostella
Match: EDO48217 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKB1])

HSP 1 Score: 301.597 bits (771), Expect = 8.599e-94
Identity = 207/601 (34.44%), Postives = 330/601 (54.91%), Query Frame = 2
Query:   77 NSLFIDIGNSESQNNKAFENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGF--CAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMR-----NTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRI 1858
            NS F+   +++ +     + +LKQ +KSG LNL+NR ++E+P  V++IN+    + KS+S +  D  WWD V LTKLIL +NS++ IS D+  L  L  LDI DN++++LP+ I +L+ L+  N+  NKI  LP  +     L +L   +N+ KSL   L  L NL  +D+S+N +S   P +  L  L  L+LS N +  +P   + L  L  L++S NK+  F         + ++    N LT  P V    +LKE+ L +N I+E+     +    +  L + +N +  IPE+I IL  L  LDL+NND+  LP  +G+M  LK L ++GNP R L+R I+  G  +I ++L+ R        ++   S  P    L   ++      +D   L  T  +  S +  A +  E+L +  +  VK ++ + N  +  P +I   S S+ DL+L  N+I+ LP+ I S + L  LD+  N++  LP+  + +  L   I+SYN   + +P V+  M  L+TL+     + +ID + +  +S LE L++ NN IS +PPELG    +K+L L GN F+ PR AI++KGT +++EYLR RI
Sbjct:    7 NSGFVGRQSAQEEKGSISDAVLKQGRKSGQLNLSNRGLTEVPEKVWRINLDVPEEAKSVSLDCEDR-WWDQVDLTKLILASNSLTEISGDVFNLPALVLLDIHDNSLTTLPEEIGSLSCLQKLNLGHNKISSLPMSMAQLESLCSLKLEHNSFKSLECWLGSLRNLEELDVSYNMVSSL-PSLAGLKHLRTLNLSNNALEMLPPEFDHLQALDDLNISSNKICNFPGKLYNMKSLRRLDCRQNHLTSVPSVGQCPSLKELYLAYNKIAELDSKVFAGYSGLTVLDLHDNLLTSIPEDIIILRDLERLDLTNNDISGLPYKIGNMSNLKSLVLNGNPLRELRRDIVMRGTQAIMKHLKSRIPDDDGATDQPDASVAP----LPSVSMGSSGAVVDMHTLGHTKTLNYSGKKSASIPVEVLEAAVTSEVKTVDFSKNMLTDLPERITALSSSVSDLNLGFNKITSLPSGICSFTQLEFLDLRNNQLSSLPDGFASLRSLREIIISYNRF-SCLPPVLYSMTSLRTLLACDNQIAVIDVDGLLRMSVLETLDLQNNNISQVPPELGNVRGLKALQLGGNPFRTPRAAILAKGTQALLEYLRDRI 600          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Nematostella
Match: EDO37499 (Leucine-rich repeat protein soc-2 homolog [Source:UniProtKB/Swiss-Prot;Acc:A7SFP1])

HSP 1 Score: 112.849 bits (281), Expect = 4.250e-26
Identity = 106/371 (28.57%), Postives = 173/371 (46.63%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQI-----------------------------------ENYLE-----------LQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMP-----------FTLE-------------RLHNLQILDLSQNKLQTFSEG----FCAPVHQIWLHVNRLTKFPIVLPNKN--LKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFG 1180
            L +L L  N I+ +  ++ LL  L  L +S+NN+++LPD++  LT+LK  ++  NKI+++PD I                                   EN ++           L TL  S+N +++LP  +    ++T +DL HN+I   P  I  L  +T+L L YNQ++S+P           F +E              L NL  L LS+NK + F  G    FC  V+   +  NR+ K P  + NK   L ++++  N ++ +  D  S I ++  L +A N+I+ +PE+I  L +L  L LSNN +K LP  +G + +L+ L I+ N    +   I      S++R +   N     P+S G
Sbjct:  111 LRELYLYGNRIAVLPPEVGLLPNLETLALSENNLTTLPDNLVKLTKLKVLDLRHNKIKEIPDVIYKLTTLTTLYLRFNRISVVESGIGNLKLLERLSLRENKIKILPRVIGQLVHLVTLDISHNHIENLPAEIGNCVHMTSLDLQHNDIPSLPDSIGRLTAMTRLGLRYNQLSSLPDSLANCSGIDEFNIEGNNIAELPEKLLSSLKNLTSLTLSRNKFEVFPAGPPKQFCQ-VNTFIMEHNRMQKIPFGVFNKAKYLSKLNVKDNQLTSLPLDFGSWI-SLVELNVATNQISKLPEDIQWLVNLEVLILSNNLLKKLPRGIGALRKLRVLDIEENKLESIPTEI--EYLRSLERLVLQSNCLGSLPRSIG 477          

HSP 2 Score: 109.768 bits (273), Expect = 3.867e-25
Identity = 136/504 (26.98%), Postives = 235/504 (46.63%), Query Frame = 2
Query:  368 SHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVK-LSFRNLADLSDEILNSLHSIPVK--------GINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPA-IISKGTASVMEYLR 1849
            + LD+S   ++ LP  +  LT L+   +  N+I  LP ++     L+TL+ S N L +LP  L  L+ L ++DL HN+I E P  I +L  LT L L +N+I+ +   +  L  L+ L L +NK++         VH + L +                    +HN I  +  + +    ++ +L + +N I  +P+ I  LT+++ L L  N + +LP SL +   +   +I+GN    L   +++S  +     L  RN  E  P   GP  Q     T   +   + +         K LS  N+ D      N L S+P+          +N+  N+ S  P  I Q+  +L+ L LSNN + +LP  I +L  LR LDI  NK+  +P  +  +  L   +L  N +G ++P  +  ++ +  L +    L  +  E   M S  ++    N  + ++P EL LC  ++ ++++ NC     P+ I++ G + V++YLR
Sbjct:   89 TRLDLSKAAVTVLPKELKELTSLRELYLYGNRIAVLPPEVGLLPNLETLALSENNLTTLPDNLVKLTKLKVLDLRHNKIKEIPDVIYKLTTLTTLYLRFNRISVVESGIGNLKLLERLSLRENKIKILPRVIGQLVHLVTLDI--------------------SHNHIENLPAE-IGNCVHMTSLDLQHNDIPSLPDSIGRLTAMTRLGLRYNQLSSLPDSLANCSGIDEFNIEGNNIAELPEKLLSSLKNLTSLTLS-RNKFEVFPA--GPPKQFCQVNTFIMEHNRMQKIPFGVFNKAKYLSKLNVKD------NQLTSLPLDFGSWISLVELNVATNQISKLPEDI-QWLVNLEVLILSNNLLKKLPRGIGALRKLRVLDIEENKLESIPTEIEYLRSLERLVLQSNCLG-SLPRSIGYLSSVTYLSVGENELVSVPQEIGNMESLEQLYLNDNENLQSLPYELVLCGSLQIMSIE-NCPLSALPSQIVAGGPSLVIQYLR 559          

HSP 3 Score: 81.2629 bits (199), Expect = 4.446e-16
Identity = 97/416 (23.32%), Postives = 171/416 (41.11%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNIS-----------------------SLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLP-KGLNCLSNLTIMDLSHNEISEFPP-------QINELYL-----------------------------------------LTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEIS-ILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRN 1150
            +NL+K  K    L+L +  I EIP+ +YK+        +       +S   +   L +L L  N I  + + I  L  L  LDIS N+I                        SLPDSI  LT +    +  N++  LPD + N   +   +   N +  LP K L+ L NLT + LS N+   FP        Q+N   +                                         L +L+++ NQI+ +P  ++ L NL++L LS N L+    G  A   +  + +  N+L   P  +   ++L+ + L  N +  + +  +  + ++  L++  N++  +P+EI  + +        N ++++LP  L     L+ +SI+  P   L   I+  G   + +YLR++ 
Sbjct:  149 DNLVKLTKLK-VLDLRHNKIKEIPDVIYKLTTLTTLYLRFNRISVVESGIGNLKLLERLSLRENKIKILPRVIGQLVHLVTLDISHNHIENLPAEIGNCVHMTSLDLQHNDIPSLPDSIGRLTAMTRLGLRYNQLSSLPDSLANCSGIDEFNIEGNNIAELPEKLLSSLKNLTSLTLSRNKFEVFPAGPPKQFCQVNTFIMEHNRMQKIPFGVFNKAKYLSKLNVKDNQLTSLPLDFGSWISLVELNVATNQISKLPEDIQWLVNLEVLILSNNLLKKLPRGIGALRKLRVLDIEENKLESIPTEIEYLRSLERLVLQSNCLGSLPRS-IGYLSSVTYLSVGENELVSVPQEIGNMESLEQLYLNDNENLQSLPYELVLCGSLQIMSIENCPLSALPSQIVAGGPSLVIQYLRLQG 562          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Nematostella
Match: EDO38039 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SE32])

HSP 1 Score: 89.7373 bits (221), Expect = 4.179e-19
Identity = 106/427 (24.82%), Postives = 194/427 (45.43%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNC-LSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIAD--IPEEISILTXXXXXX--XXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSG------ADSIKRYLRMRNTQEEE------PKSFGP--GLQAL----NRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFN 1501
            +T L L  N +  +  D+  L  L+ L ++ N ++SLPD    L  L   ++N+N +++LP+ +    +L+ L+ + N L+ L       L++LT + +  N++SE       +  L  L+L  N I  +P     L  L++++LSQN ++   E  GF   +    +  N +   P    +    E     N       D    +PNI  L +++N+++D  +P+    ++  +     LS N +  LP S+G++++LK L + G+    L+R    +G       DS  +   +     +E      P  FG    L+ L    NR  +  DS      +L     ++LS  +L +L +   N    + ++   L+ N+ S  P      ++ ++ LDL  N++SE+P  +  L  L RLD+  N
Sbjct:    1 ITTLKLDFNDLQRLPDDLGSLASLTELYLTGNLLTSLPDVFARLGNLTELHLNENSLEELPESLGKLSKLRVLNLTGNKLEKLRDDFGAGLASLTELRIDENDLSELSVSFTLMKNLKVLELGDNHIERLPEDFGNLRKLEVVNLSQNNIEKLPESFGFLCCLKSFDITGNHIENLPERFESACFLEHLYADNNNITWLPDWFGDLPNIINLCLSDNELSDSALPDHFGSISGKTLSSLDLSGNRITKLPDSMGELKELKTLHL-GSTINELERRAFQNGNWLSHLPDSFSQMANLTKLHLDENQVVCLPDDFGDLVNLEWLDVGQNRIEMLPDS----FCNLSKLWFLQLSKNHLTELPENFGNLTSLVELR---LDSNQLSSLPASFANLTN-VKTLDLYRNKLSEIPRVLLKLENLMRLDLDGN 418          

HSP 2 Score: 85.5001 bits (210), Expect = 1.041e-17
Identity = 121/443 (27.31%), Postives = 195/443 (44.02%), Query Frame = 2
Query:  503 LQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFG--PGL-------QALNRATIKDDSGFIDQT-----DLRATGIVKL--SFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGN 1783
            + TL   +N L+ LP  L  L++LT + L+ N ++  P     L  LT+L L+ N +  +P +L +L  L++L+L+ NKL+   + F A +                    +L E+ +  N +SE++    + + N+  L + +N I  +PE+   L  L  ++LS N+++ LP S G +  LK   I GN    L        A  ++      N     P  FG  P +         L+ + + D  G I        DL    I KL  S   L +L    L S  +   +    NGN  S  P    Q ++ L  L L  NQ+  LP+    L  L  LD+  N+I +LP+S   +S L    LS N +   +P+    +  L  L +    L+ +       L+N++ L++  N +S IP  L   E +  L+LDGN
Sbjct:    1 ITTLKLDFNDLQRLPDDLGSLASLTELYLTGNLLTSLPDVFARLGNLTELHLNENSLEELPESLGKLSKLRVLNLTGNKLEKLRDDFGAGL-------------------ASLTELRIDENDLSELSVS-FTLMKNLKVLELGDNHIERLPEDFGNLRKLEVVNLSQNNIEKLPESFGFLCCLKSFDITGNHIENLPERF--ESACFLEHLYADNNNITWLPDWFGDLPNIINLCLSDNELSDSALPDHFGSISGKTLSSLDLSGNRITKLPDSMGELKELKTLHLGSTINELERRAFQNGNWLSHLPDSFSQMAN-LTKLHLDENQVVCLPDDFGDLVNLEWLDVGQNRIEMLPDSFCNLSKLWFLQLSKNHL-TELPENFGNLTSLVELRLDSNQLSSLPA-SFANLTNVKTLDLYRNKLSEIPRVLLKLENLMRLDLDGN 418          

HSP 3 Score: 73.9442 bits (180), Expect = 5.634e-14
Identity = 58/186 (31.18%), Postives = 92/186 (49.46%), Query Frame = 2
Query:  149 AKKSGSLNLANRNISEIPNSVYKIN-------MPNVNDEKSISFEQSDS-SWWDDVF-----LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYN 667
             K   SL+L+   I+++P+S+ ++           +N+ +  +F+  +  S   D F     LTKL L  N +  +  D   L  L  LD+  N I  LPDS  NL++L +  ++KN + +LP+   N   L  L    N L SLP     L+N+  +DL  N++SE P  + +L  L +LDL  N
Sbjct:  233 GKTLSSLDLSGNRITKLPDSMGELKELKTLHLGSTINELERRAFQNGNWLSHLPDSFSQMANLTKLHLDENQVVCLPDDFGDLVNLEWLDVGQNRIEMLPDSFCNLSKLWFLQLSKNHLTELPENFGNLTSLVELRLDSNQLSSLPASFANLTNVKTLDLYRNKLSEIPRVLLKLENLMRLDLDGN 418          

HSP 4 Score: 70.4774 bits (171), Expect = 6.899e-13
Identity = 59/207 (28.50%), Postives = 100/207 (48.31%), Query Frame = 2
Query:  179 NRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDV------FLTKLILTANSISFISKDISLLDKLSHLDIS-------------DNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKL 742
            N NI+ +P+  +  ++PN+ +      E SDS+  D         L+ L L+ N I+ +   +  L +L  L +               N +S LPDS + +  L   ++++N++  LPD   + + L+ L    N ++ LP     LS L  + LS N ++E P     L  L +L L  NQ++S+P +   L N++ LDL +NKL
Sbjct:  193 NNNITWLPD--WFGDLPNIINLCLSDNELSDSALPDHFGSISGKTLSSLDLSGNRITKLPDSMGELKELKTLHLGSTINELERRAFQNGNWLSHLPDSFSQMANLTKLHLDENQVVCLPDDFGDLVNLEWLDVGQNRIEMLPDSFCNLSKLWFLQLSKNHLTELPENFGNLTSLVELRLDSNQLSSLPASFANLTNVKTLDLYRNKL 397          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Nematostella
Match: EDO33432 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SS78])

HSP 1 Score: 91.6633 bits (226), Expect = 4.560e-19
Identity = 81/295 (27.46%), Postives = 131/295 (44.41%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEG--FCAPVHQIWLHVNRLTKFPIVLPNKN------------------------LKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSI 1102
            L +  ++ N I  I ++I     L  LD+S N IS LPD  + L  L    +N   + +LP  I +  EL  L    N +K LP  L  LS L  +DL  NE+ E P  +  L  L +  L  N + ++P  +  L  LQI D+S+NK++   +   FC  +  + L  N L + P  +                            L+E+ LT N++ ++    + K+  +  L +  N++  +P E+   T LS   L +N ++ LP  +G+   L  L + GN    L  +I
Sbjct:   31 LQEFDISRNDICDIPENIKYCKSLVSLDLSGNPISKLPDGFSQLQHLTTLCLNDVSLIRLPPDIGSLTELTVLEARENLIKFLPVSLAFLSKLERLDLGCNELEELPDVVGSLPSLAEFWLDGNLLKTLPTEIGNLKKLQIFDVSENKIEYLPDEICFCGSLTDLHLSQNLLEELPDTIGKLKKLQLLKVDQNRLITLTPAIGGCIALQELILTENLL-DVLPSTMGKLHKLSLLNVDRNRLEVLPVELGSCTKLSVFSLRDNLLQRLPTEIGNCRNLHVLDVSGNRLECLPLTI 324          

HSP 2 Score: 84.3445 bits (207), Expect = 7.528e-17
Identity = 62/204 (30.39%), Postives = 102/204 (50.00%), Query Frame = 2
Query:  365 LSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEIS 967
            +  L +SDN I+ LP  + NL  L+ F+I++N I  +P+ I+    L +L  S N +  LP G + L +LT + L+   +   PP I  L  LT L+   N I  +P +L  L  L+ LDL  N+L+   +  G    + + WL  N L   P  + N K L+   ++ N I E   D +    ++  L ++ N + ++P+ I 
Sbjct:    8 IRRLGLSDNEIARLPPEVGNLANLQEFDISRNDICDIPENIKYCKSLVSLDLSGNPISKLPDGFSQLQHLTTLCLNDVSLIRLPPDIGSLTELTVLEARENLIKFLPVSLAFLSKLERLDLGCNELEELPDVVGSLPSLAEFWLDGNLLKTLPTEIGNLKKLQIFDVSENKI-EYLPDEICFCGSLTDLHLSQNLLEELPDTIG 210          

HSP 3 Score: 72.0182 bits (175), Expect = 5.004e-13
Identity = 74/300 (24.67%), Postives = 123/300 (41.00%), Query Frame = 2
Query:  140 LKQAKKSGSLNLANRNISEIPNSVYKINMPN---VNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFP-----------------------PQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE-------------------------GFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITK 886
            +K  K   SL+L+   IS++P+   ++       +ND   I       S  +   LT L    N I F+   ++ L KL  LD+  N +  LPD + +L  L  F ++ N ++ LP +I N  +LQ    S N ++ LP  +    +LT + LS N + E P                       P I     L +L L+ N +  +P T+ +LH L +L++ +N+L+                             G C  +H + +  NRL   P+ +    LK + L+ N    + K
Sbjct:   48 IKYCKSLVSLDLSGNPISKLPDGFSQLQHLTTLCLNDVSLIRLPPDIGSLTE---LTVLEARENLIKFLPVSLAFLSKLERLDLGCNELEELPDVVGSLPSLAEFWLDGNLLKTLPTEIGNLKKLQIFDVSENKIEYLPDEICFCGSLTDLHLSQNLLEELPDTIGKLKKLQLLKVDQNRLITLTPAIGGCIALQELILTENLLDVLPSTMGKLHKLSLLNVDRNRLEVLPVELGSCTKLSVFSLRDNLLQRLPTEIGNCRNLHVLDVSGNRLECLPLTIGTLPLKALWLSENQSQPVLK 344          

HSP 4 Score: 48.521 bits (114), Expect = 8.647e-6
Identity = 41/126 (32.54%), Postives = 67/126 (53.17%), Query Frame = 2
Query: 1406 LQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGN 1783
            ++ L LS+N+I+ LP  + +L+ L+  DIS N I  +PE++     L    LS N I + +PD  S++ +L TL ++   L  +  + I  L+ L VL    N I  +P  L    K++ L+L  N
Sbjct:    8 IRRLGLSDNEIARLPPEVGNLANLQEFDISRNDICDIPENIKYCKSLVSLDLSGNPI-SKLPDGFSQLQHLTTLCLNDVSLIRLPPD-IGSLTELTVLEARENLIKFLPVSLAFLSKLERLDLGCN 131          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Nematostella
Match: EDO46974 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNR2])

HSP 1 Score: 85.8853 bits (211), Expect = 6.730e-18
Identity = 89/334 (26.65%), Postives = 161/334 (48.20%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLT-----------------------IMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHV--NRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMR-NTQEEEPKSFG--PGLQALNRAT 1210
            L ++ L AN +  + + +  L  L  L +SDN ++ LP  ++NL  L+  + +KN I  +P+ I++   LQ +  S N +  +P+    L+NLT                       I++L  N +   P  +++L  L +LD+  N+ T +P  +  L NL  L +  N ++            ++L V  NRL   P  + + ++L ++ L++N++ EI  + +  +  + TL +  N + ++P  I  L  L  L L+ N++ +LP SLG + +L+ L+ID N    +   + +  A +I   L +R N     P S G  P LQ +N A+
Sbjct:   27 LEEVYLDANQLRDLPRGLFNLQNLQVLGLSDNELTILPSVLSNLVNLRILDFSKNGIIDIPETIKHCKNLQEIDASVNPIGKIPETFCHLANLTHLYLNDAFLDFLPGNFGRLISLRILELRENHLRVLPKSMSQLKNLERLDIGNNEFTELPMVVGCLLNLTELWMDSNAIKELRPEIGLLRRLMFLDVSKNRLEWLPPEIESLQSLTDLYLSNNLLIEI-PEQIGALGKLQTLKLEENHLGELPNSIGKLVELEELILTCNELVSLPPSLGYLRKLRVLNIDENFLESIPSELGSCTAMTI---LSLRDNRLVHLPDSIGRMPKLQVINLAS 356          

HSP 2 Score: 77.7962 bits (190), Expect = 3.406e-15
Identity = 76/265 (28.68%), Postives = 123/265 (46.42%), Query Frame = 2
Query:  314 TANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRS 1099
            + N I  I +    L  L+HL ++D  +  LP +   L  L+   + +N ++ LP  +     L+ L    N    LP  + CL NLT + +  N I E  P+I  L  L  LD+S N++  +P  +E L +L  L LS N L    E  G    +  + L  N L + P  +     L+E+ LT N +  +    L  +  +  L I  N +  IP E+   T+++ L L +N +  LP S+G M +L+ +++  N    L  S
Sbjct:  102 SVNPIGKIPETFCHLANLTHLYLNDAFLDFLPGNFGRLISLRILELRENHLRVLPKSMSQLKNLERLDIGNNEFTELPMVVGCLLNLTELWMDSNAIKELRPEIGLLRRLMFLDVSKNRLEWLPPEIESLQSLTDLYLSNNLLIEIPEQIGALGKLQTLKLEENHLGELPNSIGKLVELEELILTCNELVSLPPS-LGYLRKLRVLNIDENFLESIPSELGSCTAMTILSLRDNRLVHLPDSIGRMPKLQVINLASNRLEYLPYS 365          

HSP 3 Score: 72.4034 bits (176), Expect = 1.418e-13
Identity = 43/166 (25.90%), Postives = 88/166 (53.01%), Query Frame = 2
Query:  311 LTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGF--CAPVHQIWLHVNR 802
            ++ N + ++  +I  L  L+ L +S+N +  +P+ I  L +L+   + +N + +LP+ I   +EL+ L  + N L SLP  L  L  L ++++  N +   P ++     +T L L  N++  +P ++ R+  LQ+++L+ N+L+     F     +  +WL  N+
Sbjct:  216 VSKNRLEWLPPEIESLQSLTDLYLSNNLLIEIPEQIGALGKLQTLKLEENHLGELPNSIGKLVELEELILTCNELVSLPPSLGYLRKLRVLNIDENFLESIPSELGSCTAMTILSLRDNRLVHLPDSIGRMPKLQVINLASNRLEYLPYSFHKLVSLKALWLSENQ 381          

HSP 4 Score: 68.5514 bits (166), Expect = 2.630e-12
Identity = 44/148 (29.73%), Postives = 81/148 (54.73%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNK 739
            LT L L+ N +  I + I  L KL  L + +N++  LP+SI  L +L+   +  N++  LP  +    +L+ L+   N L+S+P  L   + +TI+ L  N +   P  I  +  L  ++L+ N++  +P++  +L +L+ L LS+N+
Sbjct:  234 LTDLYLSNNLLIEIPEQIGALGKLQTLKLEENHLGELPNSIGKLVELEELILTCNELVSLPPSLGYLRKLRVLNIDENFLESIPSELGSCTAMTILSLRDNRLVHLPDSIGRMPKLQVINLASNRLEYLPYSFHKLVSLKALWLSENQ 381          

HSP 5 Score: 58.151 bits (139), Expect = 5.426e-9
Identity = 99/408 (24.26%), Postives = 181/408 (44.36%), Query Frame = 2
Query:  572 LTIMDLSHNEISEFPPQI---NELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGN 1783
            +++++L H+ ++     +    E   L ++ L  NQ+  +P  L  L NLQ+L LS N+L                     T  P VL N  NL+ +  + N I +I  + +    N+  +  + N I  IPE    L +L++L L++  +  LP + G +  L+ L +  N  R+L +S+  S   +++R     N   E P   G     LN   +  DS  I +       + +L F                     ++++ N+    P +I     SL DL LSNN + E+P  I +L  L+ L +  N +  LP S+ ++  L   IL+ N++  ++P  +  +  L+ L +    L  I  E +   + + +L++ +N + ++P  +G   K++ +NL  N
Sbjct:    1 MSVLELRHSNLTTVSHDLFKSKEGKALEEVYLDANQLRDLPRGLFNLQNLQVLGLSDNEL---------------------TILPSVLSNLVNLRILDFSKNGIIDI-PETIKHCKNLQEIDASVNPIGKIPETFCHLANLTHLYLNDAFLDFLPGNFGRLISLRILELRENHLRVLPKSM--SQLKNLERLDIGNNEFTELPMVVG---CLLNLTELWMDSNAIKELRPEIGLLRRLMF---------------------LDVSKNRLEWLPPEIESLQ-SLTDLYLSNNLLIEIPEQIGALGKLQTLKLEENHLGELPNSIGKLVELEELILTCNELV-SLPPSLGYLRKLRVLNIDENFLESIPSE-LGSCTAMTILSLRDNRLVHLPDSIGRMPKLQVINLASN 357          

HSP 6 Score: 53.1434 bits (126), Expect = 2.219e-7
Identity = 40/149 (26.85%), Postives = 70/149 (46.98%), Query Frame = 2
Query:  155 KSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNE 601
            K  +L L   ++ E+PNS+ K+                       V L +LILT N +  +   +  L KL  L+I +N + S+P  + + T +   ++  N++  LPD I    +LQ ++ + N L+ LP   + L +L  + LS N+
Sbjct:  256 KLQTLKLEENHLGELPNSIGKL-----------------------VELEELILTCNELVSLPPSLGYLRKLRVLNIDENFLESIPSELGSCTAMTILSLRDNRLVHLPDSIGRMPKLQVINLASNRLEYLPYSFHKLVSLKALWLSENQ 381          

HSP 7 Score: 51.2174 bits (121), Expect = 7.598e-7
Identity = 57/202 (28.22%), Postives = 94/202 (46.53%), Query Frame = 2
Query: 1328 IPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSL--------------------SGLRR---LDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLR-SRIV 1861
            I ++ + L  N   + P  + Q  + L+ LD+ NN+ +ELP  +  L                      LRR   LD+S N++  LP  +  +  L+   LS N++   IP+ +  +  LQTL +    L  +    I  L  LE L ++ N + ++PP LG   K++ LN+D N F    P+ +   TA  +  LR +R+V
Sbjct:  140 ISLRILELRENHLRVLPKSMSQLKN-LERLDIGNNEFTELPMVVGCLLNLTELWMDSNAIKELRPEIGLLRRLMFLDVSKNRLEWLPPEIESLQSLTDLYLS-NNLLIEIPEQIGALGKLQTLKLEENHLGELP-NSIGKLVELEELILTCNELVSLPPSLGYLRKLRVLNIDEN-FLESIPSELGSCTAMTILSLRDNRLV 337          

HSP 8 Score: 51.2174 bits (121), Expect = 9.205e-7
Identity = 55/205 (26.83%), Postives = 93/205 (45.37%), Query Frame = 2
Query: 1262 IVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIG----------------------NTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAI 1810
            +++L   NL  +S ++  S     ++ + L+ N+    P  +F   + LQ L LS+N+++ LP+ +S+L  LR LD S N I  +PE++     L     S N IG                      + +P    R+  L+ L +    L ++  + +  L NLE L+I NN  + +P  +G    +  L +D N  K  RP I
Sbjct:    3 VLELRHSNLTTVSHDLFKSKEGKALEEVYLDANQLRDLPRGLFNLQN-LQVLGLSDNELTILPSVLSNLVNLRILDFSKNGIIDIPETIKHCKNLQEIDASVNPIGKIPETFCHLANLTHLYLNDAFLDFLPGNFGRLISLRILELRENHLRVLP-KSMSQLKNLERLDIGNNEFTELPMVVGCLLNLTELWMDSNAIKELRPEI 205          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Medaka
Match: lrrc40 (leucine rich repeat containing 40 [Source:NCBI gene;Acc:101158008])

HSP 1 Score: 306.99 bits (785), Expect = 2.151e-95
Identity = 204/583 (34.99%), Postives = 339/583 (58.15%), Query Frame = 2
Query:  134 NLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEE-----PKSFG-PGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRI 1858
             LLK A+KSG LNL+ R ++++P SVY++N      ++++SF  SD  WW+   LTKL+L++N IS IS+DI LL  L  LD+ DN +++L  +I  L +L+   ++ N++  LP ++     L++L+   N L++LP+    L NLT +DLS N +++ P  +  L  L K+ LS+N+++ +P  L +L N+++LD S N+L            + Q+ L  NRL + P  L    LKE+ + +N +  +  + L  +  I  L + +NKI  +PE++S+L +L+ LDL+NND+ +LP SL  +  LK L ++GNP R ++R ++  G + + +YLR R  +E E     P +   P    +N  +IK   G +DQ+D++   I            DE   +     V   N + NK +  P ++ Q S SL +L+L  NQ+      +  L  L  LD+  N+++ LP  +  ++ L   ILSYN    + P+V+ +M  ++T++M++  ++ +D  ++  L +L  L++SNN + +IPPELGLC  ++SL+L GN F+ PR AI++KGT +V+EYLRSRI
Sbjct:   29 GLLKAARKSGQLNLSGRALTKVPQSVYRVNE---EAQQNVSFGASDR-WWEQTDLTKLLLSSNQISQISEDIRLLPALVTLDLHDNQLNTLHSAIGELQELQTLRLSHNQLSSLPVEVCMLRNLRSLTLQQNLLENLPEEFGQLENLTELDLSKNRLTDLPQSLGRLTGLQKISLSHNKLSCLPDCLSQLTNVKLLDCSNNQLSDVPASLAHMLSLEQLHLRHNRLQRLP-QLHAPALKELYVGNNQVGVLEAEQLECLKAISVLELRDNKIRAVPEQMSLLHTLTRLDLTNNDIGSLPASLSLLPNLKVLLVEGNPLRGIRRDLLTKGTNELLKYLRGRVKEEPESSEDPPTAMTFPSQARINVHSIK-TLGVLDQSDMQVDSI-----------PDEAFLAAEGQNVVTANFSKNKLTSIPARLLQLSSSLTELNLGFNQLDHCGVEVCRLLQLTHLDLRNNQLKDLPADMENLAKLRCIILSYNRF-KSFPEVLYQMFSMETVLMANNQVSSVDPARLARLEHLSTLDLSNNDLLSIPPELGLCTSLRSLSLQGNPFRTPRAAIVAKGTDAVLEYLRSRI 593          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Medaka
Match: shoc2 (SHOC2 leucine rich repeat scaffold protein [Source:NCBI gene;Acc:101159973])

HSP 1 Score: 121.709 bits (304), Expect = 1.335e-28
Identity = 143/509 (28.09%), Postives = 248/509 (48.72%), Query Frame = 2
Query:  371 HLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIPVK--------GINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDY--EKIKMLSNLEVLXXXXXXXXXXPP-ELGLCEKIKSLNLDGNCFKVPRPA-IISKGTASVMEYLR 1849
             LD+S  +I  LP SI  L QL    +  NK+Q LP ++     L TL+ S N+L SLP  L+ L  L ++DL HN++ E P  +  L  LT L L +N+IT++   +  L  L +L + +NK++           Q+   +  L          NL  + + HN +  + K+ +     I  L + +N++ D+PE I  L S++ L L  N + A+P SL    +L+ L+++ N   +L   +++S  +     L  RN  +  P   GP  Q     ++  +   I++       RA  + KL+ ++         N L S+P+          +NL  N+ +  P  +     SL+ L LSNN + +LP+ I +L  LR LD+  NK+  LP  ++ +  L   +L+ N +  T+P  +  +  L  L +   G  ++ +  E+I  L NLE L +++N   +  P EL LC K+  ++++ NC     PA I++ G + ++++L+
Sbjct:  104 RLDLSKRSIHMLPTSIKELNQLAELYLYSNKLQSLPAEVGCLSGLVTLALSENSLTSLPDSLDSLKKLRMLDLRHNKLREIPAVVYRLTSLTTLYLRFNRITTVEKDIRNLSKLTMLSIRENKIK-----------QLPAEIGELC---------NLITLDVAHNQLEHLPKE-IGNCTQITNLDLQHNELLDLPETIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTL-ARNCFQSYPVG-GPS-QFSTIYSLNMEHNHINKIPFGIFSRAKVLSKLNMKD---------NQLTSLPLDFGTWTSMVELNLATNQLAKIPEDVCGLV-SLEVLILSNNLLKKLPHGIGNLRKLRELDLEENKLECLPNEIAYLKDLQKLVLTNNQL-TTLPRGIGHLTNLTHLGL---GENLLQHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLAIMSIE-NCPLTHLPAQIVAGGPSFIIQFLK 573          

HSP 2 Score: 115.546 bits (288), Expect = 1.525e-26
Identity = 133/517 (25.73%), Postives = 237/517 (45.84%), Query Frame = 2
Query:  158 SGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCL--------SIDGNPFRMLKRSIINSGADSIKRYLRMRNTQ-EEEPKSFG--PGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSL-HSI----PVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLT 1651
            S  L+L+ R+I  +P S+ ++N                        L +L L +N +  +  ++  L  L  L +S+N+++SLPDS+ +L +L+  ++  NK++++P  +     L TL   +N + ++ K +  LS LT++ +  N+I + P +I EL  L  LD+++NQ+  +P  +     +  LDL  N+L    E  G  A ++++ L  NRL+  P  L   + L+E++L +N IS + +  LS + N+ +LT+A N     P                         +G   Q   +         I+  PF +  R+ + S        L M++ Q    P  FG    +  LN AT +     + +      G+V L    +  LS+ +L  L H I     ++ ++L  NK    P +I    D LQ L L+NNQ++ LP  I  L+ L  L +  N ++ LPE +  +  L    L+ N   +++P  ++  + L  + + +C LT
Sbjct:  102 SMRLDLSKRSIHMLPTSIKELNQ-----------------------LAELYLYSNKLQSLPAEVGCLSGLVTLALSENSLTSLPDSLDSLKKLRMLDLRHNKLREIPAVVYRLTSLTTLYLRFNRITTVEKDIRNLSKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPETIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTLARNCFQSYP-------------------------VGGPSQFSTIYSLNMEHNHINKIPFGIFSRAKVLS-------KLNMKDNQLTSLPLDFGTWTSMVELNLATNQ-----LAKIPEDVCGLVSLE---VLILSNNLLKKLPHGIGNLRKLRELDLEENKLECLPNEIAYLKD-LQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLQHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLAIMSIENCPLT 554          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Medaka
Match: mfhas1 (malignant fibrous histiocytoma amplified sequence 1 [Source:NCBI gene;Acc:101173528])

HSP 1 Score: 115.161 bits (287), Expect = 4.712e-26
Identity = 88/266 (33.08%), Postives = 145/266 (54.51%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFC--APVHQIWLHVNRLTKFPIVLPN----KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGN 1075
            L  L L  N  +   + +  L +L  LD+S N + +L + +  L  LK   ++ NKIQ LP QI     L+ L  S+N L  LP+  + L+ L  +D  HN++S+FP +I  L  L +LDLS N+  ++P  + RL ++++L LS  ++ +  E FC    +  + L  NRL+  P   P+    + LK ++L+ N + ++    L  +  +  L ++ N+++ +PEEIS L  L NL L NN +  LP S+ D+E L+ L + GN
Sbjct:   87 LRVLELRRNKFTAAPRVLCELGQLVELDMSHNCLRTLSEGLGQLRALKKLCVSHNKIQSLPAQIGALQALEELDISFNLLHGLPRSFSSLTRLRALDADHNQLSQFPVEILALGQLEELDLSGNRFVALPANIWRLTSIKVLWLSSLRMASLPETFCRLQNLESLMLDGNRLSALP---PSFGLLQRLKMMNLSSNQL-QVFPQALLGVCGLEELYLSRNRLSHVPEEISQLGRLVNLWLDNNSITRLPDSIVDLENLEELVLQGN 348          

HSP 2 Score: 79.337 bits (194), Expect = 7.480e-15
Identity = 100/388 (25.77%), Postives = 165/388 (42.53%), Query Frame = 2
Query:  383 SDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYL-ELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDS-GFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMS 1540
            + N    LP+ I+ +  L   N+  N +Q+LP+++ + L +L+ L    N   + P+ L  L  L  +D+SHN +      + +L  L KL +S+N+I S+P  +  L  L+ LD+S N L      F +           LT+         L+ +   HN +S+   + L+ +  +  L ++ N+   +P  I  LTS+  L LS+  M +LP +   ++ L+ L +DGN    L                         P SFG  LQ L    +  +      Q  L   G+ +L                         L+ N+ S  P +I Q    L +L L NN I+ LP++I  L  L  L +  N I VLP++  ++S
Sbjct:   49 AQNQQLVLPEDISEVEAL---NLGNNSLQELPEELGSSLNKLRVLELRRNKFTAAPRVLCELGQLVELDMSHNCLRTLSEGLGQLRALKKLCVSHNKIQSLPAQIGALQALEELDISFNLLHGLPRSFSS-----------LTR---------LRALDADHNQLSQFPVEILA-LGQLEELDLSGNRFVALPANIWRLTSIKVLWLSSLRMASLPETFCRLQNLESLMLDGNRLSAL-------------------------PPSFGL-LQRLKMMNLSSNQLQVFPQALLGVCGLEELY------------------------LSRNRLSHVPEEISQLG-RLVNLWLDNNSITRLPDSIVDLENLEELVLQGNHIAVLPDNFGKLS 361          

HSP 3 Score: 63.5438 bits (153), Expect = 5.994e-10
Identity = 85/331 (25.68%), Postives = 149/331 (45.02%), Query Frame = 2
Query:  659 SYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIW---LHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEI--LNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVM 1633
            + NQ   +P   E +  ++ L+L  N LQ   E   + ++++    L  N+ T  P VL     L E+ ++HN +  +++  L ++  +  L +++NKI  +P +I  L +L  LD+S N +  LP S   + +L+ L  D N        I+  G             Q EE    G    AL     +          L +  ++ LS   +A L +    L +L S+      L+GN+ S  P   F     L+ ++LS+NQ+   P  +  + GL  L +S N++  +PE +S++  L +  L  N I   +PD +  +  L+ LV+
Sbjct:   49 AQNQQLVLP---EDISEVEALNLGNNSLQELPEELGSSLNKLRVLELRRNKFTAAPRVLCELGQLVELDMSHNCLRTLSEG-LGQLRALKKLCVSHNKIQSLPAQIGALQALEELDISFNLLHGLPRSFSSLTRLRALDADHNQLSQFPVEILALG-------------QLEELDLSGNRFVALPANIWR----------LTSIKVLWLSSLRMASLPETFCRLQNLESL-----MLDGNRLSALP-PSFGLLQRLKMMNLSSNQLQVFPQALLGVCGLEELYLSRNRLSHVPEEISQLGRLVNLWLDNNSI-TRLPDSIVDLENLEELVL 345          

HSP 4 Score: 54.6842 bits (130), Expect = 3.113e-7
Identity = 61/235 (25.96%), Postives = 102/235 (43.40%), Query Frame = 2
Query: 1283 NLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSD----------------------SLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDI-------------------GN---TIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSR 1855
            +L +L +E+ +SL+ + V  + L  NKF+  P  + +                         +L+ L +S+N+I  LP  I +L  L  LDISFN +  LP S S ++ L      +N +                   GN    +P  + R+  ++ L +S   +  +  E    L NLE L +  N +S +PP  GL +++K +NL  N  +V   A++  G   + E   SR
Sbjct:   72 SLQELPEELGSSLNKLRV--LELRRNKFTAAPRVLCELGQLVELDMSHNCLRTLSEGLGQLRALKKLCVSHNKIQSLPAQIGALQALEELDISFNLLHGLPRSFSSLTRLRALDADHNQLSQFPVEILALGQLEELDLSGNRFVALPANIWRLTSIKVLWLSSLRMASLP-ETFCRLQNLESLMLDGNRLSALPPSFGLLQRLKMMNLSSNQLQVFPQALL--GVCGLEELYLSR 301          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Medaka
Match: shoc2 (SHOC2 leucine rich repeat scaffold protein [Source:NCBI gene;Acc:101159973])

HSP 1 Score: 100.138 bits (248), Expect = 9.248e-22
Identity = 88/345 (25.51%), Postives = 168/345 (48.70%), Query Frame = 2
Query:  158 SGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLER------------------------LHNLQILDLSQNKLQTFSEGFCAPVHQIWL------HVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSI 1102
            S  L+L+ R+I  +P S+ ++N                        L +L L +N +  +  ++  L  L  L +S+N+++SLPDS+ +L +L+  ++  NK++++P  +     L TL   +N + ++ K +  LS LT++ +  N+I + P +I  L  + +L L YN+++++P +L +                        L NL  L L++N  Q++  G  +    I+       H+N++  F I    K L ++++  N ++ +  D      ++  L +A N++A IPE++  L SL  L LSNN +K LP  +G++ +L+ L ++ N    L   I
Sbjct:  102 SMRLDLSKRSIHMLPTSIKELNQ-----------------------LAELYLYSNKLQSLPAEVGCLSGLVTLALSENSLTSLPDSLDSLKKLRMLDLRHNKLREIPAVVYRLTSLTTLYLRFNRITTVEKDIRNLSKLTMLSIRENKIKQLPAEIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTLARNCFQSYPVGGPSQFSTIYSLNMEHNHINKIP-FGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNLATNQLAKIPEDVCGLVSLEVLILSNNLLKKLPHGIGNLRKLRELDLEENKLECLPNEI 421          

HSP 2 Score: 89.7373 bits (221), Expect = 2.054e-18
Identity = 128/462 (27.71%), Postives = 222/462 (48.05%), Query Frame = 2
Query:  512 LSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDL----RATGIVKLSFRNLADLSDEILNSLHSIPVK--------GINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDY--EKIKMLSNLEVLXXXXXXXXXXPP-ELGLCEKIKSLNLDGNCFKVPRPA-IISKGTASVMEYLR 1849
            L  S  ++  LP  +  L+ L  + L  N++   P ++  L  L  L LS N +TS+P +L+ L  L++LDL  NKL+           +I   V RLT         +L  + L  N I+ + KD +  +  +  L+I  NKI  +P EI  L S++ L L  N + A+P SL    +L+ L+++ N   +L   +++S  +     L  RN  +  P   GP  Q     ++  +   I++       RA  + KL+ ++         N L S+P+          +NL  N+ +  P  +     SL+ L LSNN + +LP+ I +L  LR LD+  NK+  LP  ++ +  L   +L+ N +  T+P  +  +  L  L +   G  ++ +  E+I  L NLE L +++N   +  P EL LC K+  ++++ NC     PA I++ G + ++++L+
Sbjct:  105 LDLSKRSIHMLPTSIKELNQLAELYLYSNKLQSLPAEVGCLSGLVTLALSENSLTSLPDSLDSLKKLRMLDLRHNKLR-----------EIPAVVYRLT---------SLTTLYLRFNRITTVEKD-IRNLSKLTMLSIRENKIKQLPAEIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTL-ARNCFQSYPVG-GPS-QFSTIYSLNMEHNHINKIPFGIFSRAKVLSKLNMKD---------NQLTSLPLDFGTWTSMVELNLATNQLAKIPEDVCGLV-SLEVLILSNNLLKKLPHGIGNLRKLRELDLEENKLECLPNEIAYLKDLQKLVLTNNQL-TTLPRGIGHLTNLTHLGL---GENLLQHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLAIMSIE-NCPLTHLPAQIVAGGPSFIIQFLK 527          

HSP 3 Score: 75.0998 bits (183), Expect = 1.061e-13
Identity = 50/147 (34.01%), Postives = 79/147 (53.74%), Query Frame = 2
Query:  365 LSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVN 799
            LS L++ DN ++SLP      T +   N+  N++ K+P+ +   + L+ L  S N LK LP G+  L  L  +DL  N++   P +I  L  L KL L+ NQ+T++P  +  L NL  L L +N LQ   E  G    + +++L+ N
Sbjct:  335 LSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLAKIPEDVCGLVSLEVLILSNNLLKKLPHGIGNLRKLRELDLEENKLECLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLQHLPEEIGTLENLEELYLNDN 481          
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Medaka
Match: lrrc7 (leucine rich repeat containing 7 [Source:NCBI gene;Acc:101170832])

HSP 1 Score: 100.908 bits (250), Expect = 1.901e-21
Identity = 90/298 (30.20%), Postives = 144/298 (48.32%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLT-----------------------IMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIW---LHVNRLTKFPI-VLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIIN 1108
            L +L L AN I  + K +     L  L + DN++S+LP +I +L  LK  +I+KN IQ+ PD I+    L  +  S N +  LP G   L NLT                       I++L  N +   P  I+ L  L +LDL  N+ + +P  LE++HNL+ L L  N LQT   G    + Q+    L  NR+      V   + L+++ L+ NM+  +  D +  +  + TL + +N++  +P  I  L+ L   D S N++++LP ++G +  L+  + D N    L R I N
Sbjct:   61 LEELYLDANQIEELPKQLFNCQALKKLSMPDNDLSNLPTTIASLVNLKELDISKNGIQEFPDNIKCCKGLSVVEASVNPITKLPDGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLRILELRENHLKTMPKSIHRLTQLERLDLGSNEFSEVPEVLEQIHNLKELWLDNNSLQTIP-GSIGKLRQLRYLDLAKNRIETLDSDVSGCEALEDLLLSSNMLQHLP-DSIGMLKKLTTLKVDDNQLTSLPHTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLTELPREIGN 356          

HSP 2 Score: 87.0409 bits (214), Expect = 3.444e-17
Identity = 65/217 (29.95%), Postives = 113/217 (52.07%), Query Frame = 2
Query:   89 IDIGNSESQNNKAFENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNK 739
            +D+G++E         +L+Q      L L N ++  IP S+ K+      D      E  DS       L  L+L++N +  +   I +L KL+ L + DN ++SLP +I +L+ L+ F+ + N+++ LP  I     L+T +   N L  LP+ +    N+T+M L  N++   P +I ++  L  L+LS N++ ++PFT  +L +L  L LS N+
Sbjct:  202 LDLGSNEF---SEVPEVLEQIHNLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIETLDSDVSGCEALEDLLLSSNMLQHLPDSIGMLKKLTTLKVDDNQLTSLPHTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLTELPREIGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLKNLPFTFTKLKDLAALWLSDNQ 415          

HSP 3 Score: 70.8626 bits (172), Expect = 3.327e-12
Identity = 55/179 (30.73%), Postives = 82/179 (45.81%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSE--GFCAPVHQIWLHVNRLTKFPIVL 826
            L +L L  NS+  I   I  L +L +LD++ N I +L   ++    L+   ++ N +Q LPD I    +L TL    N L SLP  +  LS L   D S NE+   PP I  L+ L       N +T +P  +    N+ ++ L  NKL+   +  G    +  + L  NRL   P   
Sbjct:  222 LKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIETLDSDVSGCEALEDLLLSSNMLQHLPDSIGMLKKLTTLKVDDNQLTSLPHTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLTELPREIGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLKNLPFTF 400          

HSP 4 Score: 56.225 bits (134), Expect = 1.210e-7
Identity = 94/403 (23.33%), Postives = 183/403 (45.41%), Query Frame = 2
Query:  626 NELYLLTKLDLSYNQITSMP---FTLERLHNLQILDLSQNKLQTFSEGF--CAPVHQIWLHVNRLTKFPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFK 1792
             E  +++ LD S+  +  +P   F+ ER   L+ L L  N+++   +    C  + ++ +  N L+  P  + +  NLKE+ ++ N I E   D++     +  +  + N I  +P+  + L +L+ L L++  ++ LP + G + +L+ L +  N  + + +SI              R TQ          L+ L+          +   +      V     NL +L  +  NSL +IP        ++ ++L  N+       +    ++L+DL LS+N +  LP++I  L  L  L +  N++  LP ++  +S L  F  S N++  ++P  +  ++ L+T       LT +  E I    N+ V+++ +N +  +P E+G   K++ LNL  N  K
Sbjct:   32 GEEEVISVLDYSHCSLQQVPKEIFSFER--TLEELYLDANQIEELPKQLFNCQALKKLSMPDNDLSNLPTTIASLVNLKELDISKNGIQEFP-DNIKCCKGLSVVEASVNPITKLPDGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLRILELRENHLKTMPKSI-------------HRLTQ----------LERLD----------LGSNEFSEVPEVLEQIHNLKELWLDN-NSLQTIPGSIGKLRQLRYLDLAKNRIETLDSDV-SGCEALEDLLLSSNMLQHLPDSIGMLKKLTTLKVDDNQLTSLPHTIGSLSLLEEFDCSCNEL-ESLPPTIGYLHSLRTFAADENFLTELPRE-IGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLK 394          
BLAST of Leucine-rich repeat-containing protein 40 vs. Planmine SMEST
Match: SMESG000063073.1 (SMESG000063073.1)

HSP 1 Score: 1171.76 bits (3030), Expect = 0.000e+0
Identity = 611/615 (99.35%), Postives = 612/615 (99.51%), Query Frame = 2
Query:   23 MSKFREFRSKNKLNPSNDNSLFIDIGNSESQNNKAFENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVTN 1867
            MSKFREFRSKNKLNPSNDNSLFIDIGN+ESQNNKAFENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLN LSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKL TFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTSLSNLDLSNNDMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRA IKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLNISNNAISNIPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVTN
Sbjct:    1 MSKFREFRSKNKLNPSNDNSLFIDIGNTESQNNKAFENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNRLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLLTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTSLSNLDLSNNDMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRAAIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLNISNNAISNIPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVTN 615          
BLAST of Leucine-rich repeat-containing protein 40 vs. Planmine SMEST
Match: SMESG000004186.1 (SMESG000004186.1)

HSP 1 Score: 347.821 bits (891), Expect = 7.137e-111
Identity = 224/590 (37.97%), Postives = 345/590 (58.47%), Query Frame = 2
Query:  131 ENLLKQAKKSGSLNLANRNISEIPNSVYKINMPNVNDEKSISFEQSDS----SWWDDVFLTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSG------FIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEM-SCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRIVTN 1867
            +N++  A+K+G+L L N    EIP  +Y IN P   D++ I +E  DS    SWW+DV LTKL L++N I  +S+DI  L  L +LD+ +NN+ ++PD I +L QL+Y N++KNKI  LP+ I     LQ +    N LK LP     L +L ++DLS+NE S  P  I     L +L +SYN++  +P  + +L  L   D+SQNK+  F +   A    + +++N +T FP+     +LKE+ + +N I+ ++  H+S IPNI  LTI+ N + ++P EI  L  L  LD+S N++ ++P +LG+M+ L+ L +DGNPFR + R+ I SG + +KRYLR R+   E+  SF P L  L   +I+ ++G       ID  +L +TG + LS RN+  + +          +K +NL  NK   FP+ I   + S+  LDLS N++ EL +  +    L+ L+++ N +R LPES + M + L+   +++N +G  +P+V+  +  L+ L  S+C + II+ +    L  L  L++SNN I  IPPE GLCE IK  NLDGN  + P    +S GT  V EYLRS+I +N
Sbjct:   42 KNIIDDARKTGTLTLINFGFDEIPTDIYNINRP---DKRRIGYEGFDSEDRNSWWEDVLLTKLDLSSNHIKKVSEDIRFLSNLLYLDLQNNNLKTIPDEICDLAQLRYLNLSKNKITVLPESIGTLNHLQQIILGNNLLKLLPTEFCRLLSLEVLDLSNNEFSHIPDAIGNFIKLKRLSISYNKLEKLPKNICKLKALIYFDVSQNKISEFPKDLDASFEVLKVNINMITLFPVSRLTPSLKELHIDNNQITTLSSLHISYIPNINILTISKNNVIELPNEIIDLKYLVQLDVSFNNLHSIPYALGNMDTLQVLCVDGNPFRSINRTAITSGTEILKRYLRTRSNM-EDITSF-PSLAPLPINSIESEAGNDISVLHIDAHELNSTGSLDLSNRNITSIPENYFELFKFKKIKVVNLGHNKLVEFPIGILSCAFSIVTLDLSFNRLLELSDVFNHFVSLKALNLNGNYLRTLPESFTTMKNTLNTLEVAHNPLGLELPEVIFNLVNLKYLNASYCAIVIINPKNFMRLKLLTELDLSNNEIEIIPPEFGLCEHIKIANLDGNKIRHPALTSVSHGTEVVFEYLRSQIQSN 626          
BLAST of Leucine-rich repeat-containing protein 40 vs. Planmine SMEST
Match: SMESG000013154.1 (SMESG000013154.1)

HSP 1 Score: 105.145 bits (261), Expect = 2.336e-23
Identity = 111/413 (26.88%), Postives = 188/413 (45.52%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSE 1534
            + +  L AN I  + K+   L KL  L +SDN ++ +P+SI N   L   ++++N I  +   I+   EL++L  S N +  LP+G + L NL +++L+ N ++E P     L LL KL+L  N + ++P +  +  +L+ILDL  N+ Q F +              +L+          L+E+SL +N +  + ++ L  + N+  L ++ N +  I EEI  L  L++  LS N + +LP ++G++++L  L +D N    L   I       ++      N   + P S G                       R + +V L+            N+L+SIP +    N        L I  F D         N I  LP+ I ++  L  LDIS N+I  LP S+++
Sbjct:   39 IEECFLDANQIKDLPKNFFKLSKLRVLTLSDNELTYIPESIGNFNHLVELDVSRNHIDSVHYNIKFCNELRSLDLSNNPINRLPEGFSSLRNLIVLNLNDNSLTELPNDFGNLSLLQKLELRDNCLKTLPNSFSKFVHLEILDLGGNEFQEFPKSLA-----------KLSA---------LRELSLDNNELQNLPQE-LGTLKNLQQLDVSENFLEVICEEIGNLEQLTDFALSQNSLDSLPNNIGNLKELTILKVDQNKLMSLTTHI--GSCSKLQELYLTENLLTKLPGSLG-----------------------RLSKLVHLNVDR---------NNLNSIPPELSKCN-------ELSIMSFRD---------NHIRRLPDEIGNMKKLHVLDISINQIDRLPLSIAQ 380          

HSP 2 Score: 66.6254 bits (161), Expect = 3.063e-11
Identity = 87/345 (25.22%), Postives = 160/345 (46.38%), Query Frame = 2
Query:  833 KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMR---NTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRI 1858
            ++++E  L  N I ++ K+   K+  +  LT+++N++  IPE I     L  LD+S N + ++  ++    +L+ L +  NP   L       G  S++  + +    N+  E P  FG  L  L +  ++D+              +  SF     L  EIL+           L GN+F  FP  + + S +L++L L NN++  LP  + +L  L++LD+S N + V+ E +  +  L+ F LS N + +++P+ +  +  L  L +    L  +    I   S L+ L ++ N ++ +P  LG   K+  LN+D N      P +      S+M +  + I
Sbjct:   37 RSIEECFLDANQIKDLPKNFF-KLSKLRVLTLSDNELTYIPESIGNFNHLVELDVSRNHIDSVHYNIKFCNELRSLDLSNNPINRLPE-----GFSSLRNLIVLNLNDNSLTELPNDFG-NLSLLQKLELRDN----------CLKTLPNSFSKFVHL--EILD-----------LGGNEFQEFPKSLAKLS-ALRELSLDNNELQNLPQELGTLKNLQQLDVSENFLEVICEEIGNLEQLTDFALSQNSL-DSLPNNIGNLKELTILKVDQNKLMSLTTH-IGSCSKLQELYLTENLLTKLPGSLGRLSKLVHLNVDRNNLNSIPPELSKCNELSIMSFRDNHI 348          
BLAST of Leucine-rich repeat-containing protein 40 vs. Planmine SMEST
Match: SMESG000013154.1 (SMESG000013154.1)

HSP 1 Score: 104.76 bits (260), Expect = 2.477e-23
Identity = 111/413 (26.88%), Postives = 188/413 (45.52%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSE 1534
            + +  L AN I  + K+   L KL  L +SDN ++ +P+SI N   L   ++++N I  +   I+   EL++L  S N +  LP+G + L NL +++L+ N ++E P     L LL KL+L  N + ++P +  +  +L+ILDL  N+ Q F +              +L+          L+E+SL +N +  + ++ L  + N+  L ++ N +  I EEI  L  L++  LS N + +LP ++G++++L  L +D N    L   I       ++      N   + P S G                       R + +V L+            N+L+SIP +    N        L I  F D         N I  LP+ I ++  L  LDIS N+I  LP S+++
Sbjct:   39 IEECFLDANQIKDLPKNFFKLSKLRVLTLSDNELTYIPESIGNFNHLVELDVSRNHIDSVHYNIKFCNELRSLDLSNNPINRLPEGFSSLRNLIVLNLNDNSLTELPNDFGNLSLLQKLELRDNCLKTLPNSFSKFVHLEILDLGGNEFQEFPKSLA-----------KLSA---------LRELSLDNNELQNLPQE-LGTLKNLQQLDVSENFLEVICEEIGNLEQLTDFALSQNSLDSLPNNIGNLKELTILKVDQNKLMSLTTHI--GSCSKLQELYLTENLLTKLPGSLG-----------------------RLSKLVHLNVDR---------NNLNSIPPELSKCN-------ELSIMSFRD---------NHIRRLPDEIGNMKKLHVLDISINQIDRLPLSIAQ 380          

HSP 2 Score: 66.6254 bits (161), Expect = 3.405e-11
Identity = 87/345 (25.22%), Postives = 160/345 (46.38%), Query Frame = 2
Query:  833 KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMR---NTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFKVPRPAIISKGTASVMEYLRSRI 1858
            ++++E  L  N I ++ K+   K+  +  LT+++N++  IPE I     L  LD+S N + ++  ++    +L+ L +  NP   L       G  S++  + +    N+  E P  FG  L  L +  ++D+              +  SF     L  EIL+           L GN+F  FP  + + S +L++L L NN++  LP  + +L  L++LD+S N + V+ E +  +  L+ F LS N + +++P+ +  +  L  L +    L  +    I   S L+ L ++ N ++ +P  LG   K+  LN+D N      P +      S+M +  + I
Sbjct:   37 RSIEECFLDANQIKDLPKNFF-KLSKLRVLTLSDNELTYIPESIGNFNHLVELDVSRNHIDSVHYNIKFCNELRSLDLSNNPINRLPE-----GFSSLRNLIVLNLNDNSLTELPNDFG-NLSLLQKLELRDN----------CLKTLPNSFSKFVHL--EILD-----------LGGNEFQEFPKSLAKLS-ALRELSLDNNELQNLPQELGTLKNLQQLDVSENFLEVICEEIGNLEQLTDFALSQNSL-DSLPNNIGNLKELTILKVDQNKLMSLTTH-IGSCSKLQELYLTENLLTKLPGSLGRLSKLVHLNVDRNNLNSIPPELSKCNELSIMSFRDNHI 348          
BLAST of Leucine-rich repeat-containing protein 40 vs. Planmine SMEST
Match: SMESG000016748.1 (SMESG000016748.1)

HSP 1 Score: 103.99 bits (258), Expect = 7.722e-23
Identity = 109/418 (26.08%), Postives = 206/418 (49.28%), Query Frame = 2
Query:  311 LTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHVNRLTKFPI-VLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRM-RNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRN--LADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSH 1552
            L+ N IS +S +I  L KL H  ++ N + ++  ++     L+  +++ NK++ +P +I N   L+  +CS+N LK+LP  +  L  L  M+LSHN+I + P +I  L  L    ++ N+I  +P ++  + +L+ ++ S N++      +   +  + L  N+    P  +     +K +SL  N +  I  + L K+ N+  L ++ N I  IP E+   T L + ++  N++   P SL    +  CL+I G   +     + N   D ++  LR+  N   E P  F             ++   I       + +V+L F +  L  +   I +  H   ++ +NL+ N   IFP    + S  L +L++S+N+ISE+ ++IS ++ L  LD+SFN++   P ++ ++  L +
Sbjct:   59 LSKNKISDLSDEIIALSKLRHFFVNGNMLRTINVNLFYARGLQSLDVSNNKLEVIPVEIANLGHLEYFNCSHNKLKALPLTIFGLLKLQYMNLSHNQIQDIPEEIGNLKSLQTFLINSNEIVLIPSSISTITSLKTIEASNNQMCHLPISWVGSLKTLKLDGNQFQFIPSQIYDCCEMKYLSLAKNYLKFIPIE-LVKLRNLRQLDLSFNSIEYIPCEMGYWTKLVDFNIHGNNITYFPQSLIANHKFVCLNISGCQLKEFPLLLCNC-YDLME--LRVGENELNELPDKFQLFCNMKYLFMNNNNFELIPLQVCLLSTLVELDFSHNFLWQVPPGIFSLKH---LRKLNLSFNNILIFPGCTAELS-YLSELNVSHNKISEICDSISWMTFLYYLDLSFNELSTFPSAIFQLRYLKY 468          

HSP 2 Score: 93.9745 bits (232), Expect = 1.109e-19
Identity = 119/439 (27.11%), Postives = 204/439 (46.47%), Query Frame = 2
Query:  467 QKLPDQIENYLELQTLSCSYNTLKSL---PKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHV--NRLTKFPI-VLPNKNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSI----KRYLR--------MRNTQ---------EEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFR------------NLADLSDEIL--NSLHSIP--------VKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMS 1636
            QK     E   E Q L C    +++L   PK +    ++ +++LS N+IS+   +I  L  L    ++ N + ++   L     LQ LD+S NKL+          H  + +   N+L   P+ +     L+ ++L+HN I +I ++ +  + ++ T  I +N+I  IP  IS +TSL  ++ SNN M  LP+S   +  LK L +DGN F+ +   I +          K YL+        +RN +         E  P   G   + ++     ++  +  Q+ +     V L+              N  DL +  +  N L+ +P        +K + +N N F + PL++   S +L +LD S+N + ++P  I SL  LR+L++SFN I + P   +E+S LS   +S+N I   I D +S M +L  L +S
Sbjct:   16 QKFHPSGEGLFEYQELKCFVYVMQNLYDVPKEIYFHPDVELINLSKNKISDLSDEIIALSKLRHFFVNGNMLRTINVNLFYARGLQSLDVSNNKLEVIPVEIANLGHLEYFNCSHNKLKALPLTIFGLLKLQYMNLSHNQIQDIPEE-IGNLKSLQTFLINSNEIVLIPSSISTITSLKTIEASNNQMCHLPISW--VGSLKTLKLDGNQFQFIPSQIYDCCEMKYLSLAKNYLKFIPIELVKLRNLRQLDLSFNSIEYIPCEMGYWTKLVDFNIHGNNITYFPQSLIANHKFVCLNISGCQLKEFPLLLCNCYDLMELRVGENELNELPDKFQLFCNMKYLFMNNNNFELIPLQVCLLS-TLVELDFSHNFLWQVPPGIFSLKHLRKLNLSFNNILIFPGCTAELSYLSELNVSHNKISE-ICDSISWMTFLYYLDLS 449          

HSP 3 Score: 79.7221 bits (195), Expect = 3.556e-15
Identity = 115/463 (24.84%), Postives = 206/463 (44.49%), Query Frame = 2
Query:  296 LTKLILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAPVHQIWLHV--NRLTKFP-----------IVLPNKN-------------LKEISLTHNMISEI-----TKDHLSKIP----NI-----CT--------LTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDDSGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMS 1540
            L   ++ +N I  I   IS +  L  ++ S+N +  LP  I+ +  LK   ++ N+ Q +P QI +  E++ LS + N LK +P  L  L NL  +DLS N I   P ++     L   ++  N IT  P +L   H    L++S  +L+ F    C     + L V  N L + P           + + N N             L E+  +HN + ++     +  HL K+     NI     CT        L +++NKI++I + IS +T L  LDLS N++   P ++  +  LK        +  L  +++++ + + K++  +R       K     ++     +I+      DQ +      + +  +NL  L++             +NL+ N+F   P  I +  ++L+ L+++NN + ELP  +S    L  +D+  N++  LP SL+ +S
Sbjct:  169 LQTFLINSNEIVLIPSSISTITSLKTIEASNNQMCHLP--ISWVGSLKTLKLDGNQFQFIPSQIYDCCEMKYLSLAKNYLKFIPIELVKLRNLRQLDLSFNSIEYIPCEMGYWTKLVDFNIHGNNITYFPQSLIANHKFVCLNISGCQLKEFPLLLCNCYDLMELRVGENELNELPDKFQLFCNMKYLFMNNNNFELIPLQVCLLSTLVELDFSHNFLWQVPPGIFSLKHLRKLNLSFNNILIFPGCTAELSYLSELNVSHNKISEICDSISWMTFLYYLDLSFNELSTFPSAIFQLRYLK--------YLNLSNNLLDNFSKTDKKWEELRTIDFSNNKFTEFPVELCVHDSIR--KLVFDQKEGTKIKSLPVEIKNLWRLAE-------------LNLSNNEFLTIPPVIMEL-ENLKVLEMANNILKELPLNLSDAKNLENIDVRNNQLTELPFSLTTLS 605          

HSP 4 Score: 65.855 bits (159), Expect = 8.020e-11
Identity = 80/293 (27.30%), Postives = 136/293 (46.42%), Query Frame = 2
Query:  305 LILTANSISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQKLPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQINELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCA--PVHQIWLHVNRLTK---FPIVLPN-KNLKEISLTHNMISEITKDHLSKIPNICTLTIANNKIADIPEEISILTXXXXXXXXXXXMKALPLSLGDMEQLKCLSIDGNPFRMLKRSI-INSGADSIKRYLRMRNTQEE 1162
            L +  N+   I   + LL  L  LD S N +  +P  I +L  L+  N++ N I   P        L  L+ S+N +  +   ++ ++ L  +DLS NE+S FP  I +L  L  L+LS N + +   T ++   L+ +D S NK   F    C    + ++       TK    P+ + N   L E++L++N    I    + ++ N+  L +ANN + ++P  +S   +L N+D+ NN +  LP SL  +        DG+P       + I    +SI+ +LR     E+
Sbjct:  354 LFMNNNNFELIPLQVCLLSTLVELDFSHNFLWQVPPGIFSLKHLRKLNLSFNNILIFPGCTAELSYLSELNVSHNKISEICDSISWMTFLYYLDLSFNELSTFPSAIFQLRYLKYLNLSNNLLDNFSKTDKKWEELRTIDFSNNKFTEFPVELCVHDSIRKLVFDQKEGTKIKSLPVEIKNLWRLAELNLSNNEFLTIPPV-IMELENLKVLEMANNILKELPLNLSDAKNLENIDVRNNQLTELPFSLTTLSNKIKFKFDGSPLVNPPLIVCIGGNMESIQSFLRHNQAFED 645          

HSP 5 Score: 60.8474 bits (146), Expect = 2.749e-9
Identity = 53/177 (29.94%), Postives = 101/177 (57.06%), Query Frame = 2
Query: 1262 IVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSIFPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPESLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKIKMLSNLEVLXXXXXXXXXXPPELGLCEKIKSLNLDGNCFK 1792
            ++ LS   ++DLSDEI+ +L  +  +   +NGN      + +F ++  LQ LD+SNN++  +P  I++L  L   + S NK++ LP ++  +  L +  LS+N I + IP+ +  +  LQT +++   + +I    I  +++L+ +  SNN + ++P  +     +K+L LDGN F+
Sbjct:   56 LINLSKNKISDLSDEII-ALSKL--RHFFVNGNMLRTINVNLF-YARGLQSLDVSNNKLEVIPVEIANLGHLEYFNCSHNKLKALPLTIFGLLKLQYMNLSHNQIQD-IPEEIGNLKSLQTFLINSNEIVLIP-SSISTITSLKTIEASNNQMCHLP--ISWVGSLKTLKLDGNQFQ 224          
The following BLAST results are available for this feature:
BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
LRRC401.294e-9235.14leucine rich repeat containing 40 [Source:HGNC Sym... [more]
LRRD12.381e-2927.73leucine rich repeats and death domain containing 1... [more]
LRRD12.381e-2927.73leucine rich repeats and death domain containing 1... [more]
MFHAS15.214e-2528.57malignant fibrous histiocytoma amplified sequence ... [more]
MFHAS15.446e-2528.57malignant fibrous histiocytoma amplified sequence ... [more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
soc-27.179e-2827.20Leucine-rich repeat protein soc-2 [Source:UniProt... [more]
soc-27.441e-2827.20Leucine-rich repeat protein soc-2 [Source:UniProt... [more]
soc-21.167e-2727.20Leucine-rich repeat protein soc-2 [Source:UniProt... [more]
soc-21.167e-2727.20Leucine-rich repeat protein soc-2 [Source:UniProt... [more]
soc-21.989e-2727.20Leucine-rich repeat protein soc-2 [Source:UniProt... [more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
f-cup8.110e-6630.37gene:FBgn0028487 transcript:FBtr0082847[more]
f-cup2.337e-6530.37gene:FBgn0028487 transcript:FBtr0082846[more]
f-cup1.996e-5829.74gene:FBgn0028487 transcript:FBtr0112939[more]
f-cup1.099e-4332.58gene:FBgn0028487 transcript:FBtr0334528[more]
f-cup2.885e-4332.58gene:FBgn0028487 transcript:FBtr0334527[more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lrrc403.364e-9834.98leucine rich repeat containing 40 [Source:NCBI gen... [more]
shoc21.158e-2727.76SHOC2 leucine rich repeat scaffold protein [Source... [more]
shoc21.158e-2727.76SHOC2 leucine rich repeat scaffold protein [Source... [more]
shoc21.158e-2727.76SHOC2 leucine rich repeat scaffold protein [Source... [more]
lrrc72.590e-2229.97leucine rich repeat containing 7 [Source:ZFIN;Acc:... [more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pparg1.542e-9034.30peroxisome proliferator activated receptor gamma [... [more]
pparg1.174e-8834.65peroxisome proliferator activated receptor gamma [... [more]
pparg3.532e-8534.02peroxisome proliferator activated receptor gamma [... [more]
pparg5.927e-8533.96peroxisome proliferator activated receptor gamma [... [more]
pparg3.917e-8233.90peroxisome proliferator activated receptor gamma [... [more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Lrrc402.339e-9035.26leucine rich repeat containing 40 [Source:MGI Symb... [more]
Lrrc12.257e-2532.72leucine rich repeat containing 1 [Source:MGI Symbo... [more]
Lrrd15.079e-2526.93leucine rich repeats and death domain containing 1... [more]
Lrrc11.231e-2430.10leucine rich repeat containing 1 [Source:MGI Symbo... [more]
Shoc22.800e-2327.55Shoc2, leucine rich repeat scaffold protein [Sourc... [more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7SXW3|LRC40_DANRE9.900e-9835.15Leucine-rich repeat-containing protein 40 OS=Danio... [more]
sp|Q5ZLN0|LRC40_CHICK2.764e-9733.22Leucine-rich repeat-containing protein 40 OS=Gallu... [more]
sp|Q9H9A6|LRC40_HUMAN6.216e-9235.14Leucine-rich repeat-containing protein 40 OS=Homo ... [more]
sp|Q6GPJ5|LRC40_XENLA8.114e-9234.47Leucine-rich repeat-containing protein 40 OS=Xenop... [more]
sp|Q4R3P6|LRC40_MACFA8.711e-9234.97Leucine-rich repeat-containing protein 40 OS=Macac... [more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
K1QH701.726e-10235.80Leucine-rich repeat-containing protein 40 OS=Crass... [more]
A0A5N5PX814.147e-10135.69Uncharacterized protein OS=Pangasianodon hypophtha... [more]
A0A4W5P7F32.010e-9834.14Leucine rich repeat containing 40 OS=Hucho hucho O... [more]
B5DG623.138e-9834.14Leucine rich repeat containing 40 OS=Salmo salar O... [more]
A0A060WCC53.239e-9833.97Uncharacterized protein OS=Oncorhynchus mykiss OX=... [more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lrrc406.578e-9434.64leucine rich repeat containing 40 [Source:NCBI gen... [more]
lrrc401.921e-8833.28leucine rich repeat containing 40 [Source:NCBI gen... [more]
lrrc406.757e-8833.97leucine rich repeat containing 40 [Source:NCBI gen... [more]
shoc29.644e-2927.79SHOC2 leucine rich repeat scaffold protein [Source... [more]
shoc29.826e-2927.70SHOC2 leucine rich repeat scaffold protein [Source... [more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lrrc404.696e-9833.56leucine rich repeat containing 40 [Source:NCBI gen... [more]
ENSPMAT00000004940.12.705e-2423.96pep scaffold:Pmarinus_7.0:GL476356:339323:347865:-... [more]
scrib1.671e-2130.50scribble planar cell polarity protein [Source:NCBI... [more]
ENSPMAT00000008655.12.650e-1633.33pep scaffold:Pmarinus_7.0:GL484079:6946:12214:1 ge... [more]
lrch35.658e-1534.44leucine-rich repeats and calponin homology (CH) do... [more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
CYR11.008e-1926.00Adenylate cyclase; required for cAMP production an... [more]
CCR44.035e-832.41Component of the CCR4-NOT transcriptional complex;... [more]
SOG23.737e-629.41Key component of the RAM signaling network; requir... [more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO482178.599e-9434.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO374994.250e-2628.57Leucine-rich repeat protein soc-2 homolog [Source... [more]
EDO380394.179e-1924.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO334324.560e-1927.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO469746.730e-1826.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lrrc402.151e-9534.99leucine rich repeat containing 40 [Source:NCBI gen... [more]
shoc21.335e-2828.09SHOC2 leucine rich repeat scaffold protein [Source... [more]
mfhas14.712e-2633.08malignant fibrous histiocytoma amplified sequence ... [more]
shoc29.248e-2225.51SHOC2 leucine rich repeat scaffold protein [Source... [more]
lrrc71.901e-2130.20leucine rich repeat containing 7 [Source:NCBI gene... [more]
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BLAST of Leucine-rich repeat-containing protein 40 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000063073.10.000e+099.35SMESG000063073.1[more]
SMESG000004186.17.137e-11137.97SMESG000004186.1[more]
SMESG000013154.12.336e-2326.88SMESG000013154.1[more]
SMESG000013154.12.477e-2326.88SMESG000013154.1[more]
SMESG000016748.17.722e-2326.08SMESG000016748.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30000082 ID=SMED30000082|Name=Leucine-rich repeat-containing protein 40|organism=Schmidtea mediterranea sexual|type=transcript|length=2000bp
TATAAATCTTATATGAAAATAAATGTCGAAATTTCGTGAATTCCGATCAA
AAAATAAGTTGAATCCATCAAATGACAATTCATTATTCATTGATATTGGC
AATAGTGAATCTCAAAACAATAAAGCATTCGAGAATTTACTAAAACAAGC
AAAGAAGTCAGGTTCATTAAACCTAGCTAATCGAAATATTTCTGAAATTC
CAAATAGTGTGTATAAAATAAATATGCCTAATGTAAATGATGAAAAATCA
ATCAGTTTTGAGCAAAGTGATAGCAGTTGGTGGGATGATGTATTTCTTAC
CAAATTAATACTAACTGCTAATTCAATTTCTTTCATCAGCAAAGATATTT
CTCTACTTGATAAACTCTCGCATTTGGATATAAGCGATAATAATATTTCC
TCTTTACCGGATTCTATAACAAATTTGACTCAGTTAAAGTATTTTAATAT
TAACAAAAATAAAATTCAAAAGCTACCGGATCAAATTGAAAACTACCTGG
AATTACAGACGTTATCTTGCAGTTACAATACACTGAAGAGTTTACCAAAA
GGATTAAATTGCTTGTCAAATTTAACAATTATGGATCTTTCTCATAATGA
AATTTCCGAGTTTCCGCCTCAAATTAATGAGTTATACTTGCTCACGAAAT
TGGATTTATCATATAATCAAATTACATCAATGCCATTTACCCTGGAACGA
TTACATAATTTACAAATATTGGATTTGTCCCAGAATAAATTACAAACGTT
TTCTGAAGGATTTTGTGCACCAGTTCATCAAATTTGGTTACATGTAAACC
GTCTAACGAAGTTCCCAATTGTTTTACCAAATAAAAATTTAAAAGAAATT
TCACTGACTCATAACATGATTTCTGAAATCACAAAAGATCATTTATCAAA
AATCCCAAACATATGCACACTTACAATAGCTAACAATAAAATTGCAGATA
TCCCCGAGGAAATTTCTATTTTGACAAGCTTGTCAAATTTAGACTTGAGT
AACAATGATATGAAAGCGTTACCGTTGTCTTTAGGGGACATGGAACAGCT
TAAATGCCTTTCTATTGACGGGAATCCATTTAGGATGCTTAAACGATCAA
TTATTAACAGCGGTGCAGATTCAATTAAAAGATATTTACGTATGCGTAAT
ACTCAAGAAGAAGAGCCTAAATCCTTTGGGCCCGGTCTGCAAGCATTAAA
TAGAGCGACAATTAAAGACGACTCAGGGTTTATTGATCAAACAGATTTAA
GAGCCACAGGAATTGTCAAATTATCCTTTCGAAATTTGGCAGATTTATCT
GATGAAATTTTAAATTCACTGCATTCCATTCCCGTCAAAGGAATCAATTT
AAATGGCAATAAATTCTCAATTTTTCCTTTGAAGATTTTTCAATTTTCCG
ATAGCCTTCAAGACCTCGATTTAAGTAATAATCAAATATCGGAATTACCC
AATACCATATCGTCGCTCTCTGGTTTACGGAGGTTGGATATCAGCTTCAA
TAAAATACGAGTTTTACCGGAATCTTTGTCGGAAATGAGTTGCCTTTCAC
ATTTTATTTTATCATACAATGATATTGGCAACACAATCCCAGATGTCGTT
AGTCGAATGAATTATTTGCAAACTTTAGTTATGTCGCACTGTGGCTTGAC
AATAATTGACTATGAAAAAATCAAAATGCTGTCAAATTTAGAAGTTTTAA
ATATTTCTAACAATGCAATCAGCAATATTCCCCCAGAATTGGGGTTATGT
GAGAAAATCAAATCACTGAATTTAGATGGCAATTGTTTTAAAGTTCCTCG
ACCTGCTATAATTTCGAAAGGTACAGCCTCAGTTATGGAATACCTACGTT
CCAGAATCGTGACGAATTAACGAGTTTCTATTGAATCATTAATACAATTC
TTGGACCACCGATTTGAGTCCACGTGCTTCGTAATTGAGTTAATTCTTTT
TTTGATGTGCAATTTATAATAATTTTTGTATTAAAATTTTTTAATAATTC
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protein sequence of SMED30000082-orf-1

>SMED30000082-orf-1 ID=SMED30000082-orf-1|Name=SMED30000082-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=616bp
MSKFREFRSKNKLNPSNDNSLFIDIGNSESQNNKAFENLLKQAKKSGSLN
LANRNISEIPNSVYKINMPNVNDEKSISFEQSDSSWWDDVFLTKLILTAN
SISFISKDISLLDKLSHLDISDNNISSLPDSITNLTQLKYFNINKNKIQK
LPDQIENYLELQTLSCSYNTLKSLPKGLNCLSNLTIMDLSHNEISEFPPQ
INELYLLTKLDLSYNQITSMPFTLERLHNLQILDLSQNKLQTFSEGFCAP
VHQIWLHVNRLTKFPIVLPNKNLKEISLTHNMISEITKDHLSKIPNICTL
TIANNKIADIPEEISILTSLSNLDLSNNDMKALPLSLGDMEQLKCLSIDG
NPFRMLKRSIINSGADSIKRYLRMRNTQEEEPKSFGPGLQALNRATIKDD
SGFIDQTDLRATGIVKLSFRNLADLSDEILNSLHSIPVKGINLNGNKFSI
FPLKIFQFSDSLQDLDLSNNQISELPNTISSLSGLRRLDISFNKIRVLPE
SLSEMSCLSHFILSYNDIGNTIPDVVSRMNYLQTLVMSHCGLTIIDYEKI
KMLSNLEVLNISNNAISNIPPELGLCEKIKSLNLDGNCFKVPRPAIISKG
TASVMEYLRSRIVTN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
GO:0005575cellular_component
GO:0005886plasma membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR025875Leu-rich_rpt_4
IPR003591Leu-rich_rpt_typical-subtyp
IPR032675LRR_dom_sf
IPR001611Leu-rich_rpt
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: biological process
TermDefinition
GO:0007165signal transduction
GO:0008150biological_process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00019LEURICHRPTcoord: 227..240
score: 55.04
coord: 207..220
score: 48.67
NoneNo IPR availableSMARTSM00364LRR_bac_2coord: 459..478
e-value: 9.1
score: 14.0
coord: 181..200
e-value: 290.0
score: 2.5
coord: 135..154
e-value: 220.0
score: 3.5
coord: 160..177
e-value: 470.0
score: 1.0
coord: 553..573
e-value: 140.0
score: 5.0
coord: 112..131
e-value: 15.0
score: 12.3
coord: 204..223
e-value: 210.0
score: 3.7
coord: 227..246
e-value: 400.0
score: 1.5
coord: 482..501
e-value: 7.5
score: 14.7
NoneNo IPR availableSMARTSM00365LRR_sd22_2coord: 459..477
e-value: 170.0
score: 5.5
coord: 482..504
e-value: 26.0
score: 12.2
coord: 227..249
e-value: 31.0
score: 11.5
coord: 112..137
e-value: 25.0
score: 12.4
coord: 553..584
e-value: 310.0
score: 3.5
coord: 181..206
e-value: 190.0
score: 5.2
coord: 270..299
e-value: 51.0
score: 9.8
NoneNo IPR availablePANTHERPTHR45752FAMILY NOT NAMEDcoord: 27..613
NoneNo IPR availablePANTHERPTHR45752:SF2LEUCINE-RICH REPEAT-CONTAINING PROTEIN 40coord: 27..613
NoneNo IPR availableSUPERFAMILYSSF52058L domain-likecoord: 42..358
NoneNo IPR availableSUPERFAMILYSSF52058L domain-likecoord: 417..590
IPR003591Leucine-rich repeat, typical subtypeSMARTSM00369LRR_typ_2coord: 181..203
e-value: 6.6
score: 14.7
coord: 553..576
e-value: 0.0025
score: 27.1
coord: 227..250
e-value: 1.1
score: 18.3
coord: 204..224
e-value: 7.0
score: 14.5
coord: 135..158
e-value: 17.0
score: 11.3
coord: 112..134
e-value: 5.1
score: 15.7
coord: 482..505
e-value: 0.11
score: 21.6
coord: 461..481
e-value: 25.0
score: 10.0
coord: 317..340
e-value: 6.1
score: 15.0
IPR001611Leucine-rich repeatPFAMPF13855LRR_8coord: 92..148
e-value: 4.8E-8
score: 32.6
coord: 461..518
e-value: 3.1E-9
score: 36.5
coord: 532..587
e-value: 1.7E-7
score: 30.9
coord: 272..329
e-value: 1.1E-7
score: 31.5
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 319..341
score: 5.895
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 137..158
score: 6.041
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 272..293
score: 6.903
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 555..576
score: 9.121
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 507..529
score: 4.578
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 206..228
score: 7.673
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 484..505
score: 6.834
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 91..112
score: 6.056
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 229..250
score: 6.819
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 183..204
score: 7.473
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 45..66
score: 4.501
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 160..182
score: 6.372
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 461..482
score: 9.098
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 296..317
score: 6.672
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 114..135
score: 8.336
IPR032675Leucine-rich repeat domain superfamilyGENE3DG3DSA:3.80.10.10coord: 512..611
e-value: 7.7E-20
score: 72.9
IPR032675Leucine-rich repeat domain superfamilyGENE3DG3DSA:3.80.10.10coord: 404..511
e-value: 1.0E-14
score: 56.0
IPR032675Leucine-rich repeat domain superfamilyGENE3DG3DSA:3.80.10.10coord: 28..400
e-value: 1.8E-63
score: 216.0
IPR025875Leucine rich repeat 4PFAMPF12799LRR_4coord: 207..242
e-value: 9.6E-7
score: 29.0