CYCLIN domain-containing protein

Overview
NameCYCLIN domain-containing protein
Smed IDSMED30000019
Length (bp)1059
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of CYCLIN domain-containing protein (SMED30000019) t-SNE clustered cells

Violin plots show distribution of expression levels for CYCLIN domain-containing protein (SMED30000019) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of CYCLIN domain-containing protein (SMED30000019) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for CYCLIN domain-containing protein (SMED30000019) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30000019

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30000019SMESG000066582.1 Contig1015newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30000019SMESG000066582.1 Contig1015uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30000019SMESG000033796.1 Contig1015newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30000019SMESG000033796.1 Contig1015uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
nervous systemSMED30000019SMESG000066582.1 dd_Smed_v4_13078_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30000019SMESG000066582.1 dd_Smed_v4_13078_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30000019SMESG000066582.1 dd_Smed_v4_5487_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30000019SMESG000066582.1 dd_Smed_v6_5487_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30000019SMESG000066582.1 dd_Smed_v6_13078_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Human
Match: CCNT2 (cyclin T2 [Source:HGNC Symbol;Acc:HGNC:1600])

HSP 1 Score: 92.0485 bits (227), Expect = 9.340e-20
Identity = 54/201 (26.87%), Postives = 105/201 (52.24%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYI------TCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  K     +++ +LFL+ K +++  +++ +++     L  L P  + K + Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    +A + I++A KW N+   V  D KHW++++DP++    + +L+H FL++ ++ PN LK I
Sbjct:   54 SQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPNRLKKI 254
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Human
Match: CCNT2 (cyclin T2 [Source:HGNC Symbol;Acc:HGNC:1600])

HSP 1 Score: 92.0485 bits (227), Expect = 1.155e-19
Identity = 54/201 (26.87%), Postives = 105/201 (52.24%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYI------TCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  K     +++ +LFL+ K +++  +++ +++     L  L P  + K + Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    +A + I++A KW N+   V  D KHW++++DP++    + +L+H FL++ ++ PN LK I
Sbjct:   54 SQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPNRLKKI 254
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Human
Match: CCNT1 (cyclin T1 [Source:HGNC Symbol;Acc:HGNC:1599])

HSP 1 Score: 88.1965 bits (217), Expect = 1.864e-18
Identity = 59/205 (28.78%), Postives = 102/205 (49.76%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTK--YQDKRIEMKLLVEKVLILGKLSPSKNL---KIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  +     VA  +LFL+ K   Q K++E  + V        L P ++L   + E Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    VA + I++A KW N+   V  D KHW++++D ++    + +L+H FL++ ++ PN LK I
Sbjct:   55 SQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTC----LHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPNRLKRI 255
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Human
Match: CCNT2 (cyclin T2 [Source:HGNC Symbol;Acc:HGNC:1600])

HSP 1 Score: 70.0922 bits (170), Expect = 3.171e-14
Identity = 30/80 (37.50%), Postives = 51/80 (63.75%), Query Frame = 3 
Query:  507 FICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            F+ T+ LH T F +QY    +A + I++A KW N+   V  D KHW++++DP++    + +L+H FL++ ++ PN LK I
Sbjct:   16 FMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPNRLKKI 95
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Human
Match: CCNT2 (cyclin T2 [Source:HGNC Symbol;Acc:HGNC:1600])

HSP 1 Score: 65.855 bits (159), Expect = 2.054e-12
Identity = 28/74 (37.84%), Postives = 47/74 (63.51%), Query Frame = 3 
Query:  525 LHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            LH T F +QY    +A + I++A KW N+   V  D KHW++++DP++    + +L+H FL++ ++ PN LK I
Sbjct:    4 LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPNRLKKI 77
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Fly
Match: CycT (gene:FBgn0025455 transcript:FBtr0333124)

HSP 1 Score: 68.5514 bits (166), Expect = 2.750e-12
Identity = 43/193 (22.28%), Postives = 92/193 (47.67%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYITCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDLVK-YDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLK 737
            SQ  I+  I+YMH  +   +        +A+ SLFL+ K +++  +++ ++      L   +     ++   +   E+ ++   G  + + HP+  + +     K   D   +  F+ ++ LH T   +QY    VA   IY+A KW+  ++ +  + KHWF ++D ++    +  L+  F+ ++++ P  LK
Sbjct:   88 SQLCINTAIVYMHRFYAFHSFTHFHRNSMASASLFLAAKVEEQPRKLEHVIRAANKCLPPTTEQNYAELAQELVFNENVLLQTLGFDVAIDHPHTHVVRTCQLVKACKDLAQTSYFLASNSLHLTSMCLQYRPTVVACFCIYLACKWSRWEIPQSTEGKHWFYYVDKTVSLDLLKQLTDEFIAIYEKSPARLK 280
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Fly
Match: CycT (gene:FBgn0025455 transcript:FBtr0075205)

HSP 1 Score: 68.5514 bits (166), Expect = 2.750e-12
Identity = 43/193 (22.28%), Postives = 92/193 (47.67%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYITCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDLVK-YDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLK 737
            SQ  I+  I+YMH  +   +        +A+ SLFL+ K +++  +++ ++      L   +     ++   +   E+ ++   G  + + HP+  + +     K   D   +  F+ ++ LH T   +QY    VA   IY+A KW+  ++ +  + KHWF ++D ++    +  L+  F+ ++++ P  LK
Sbjct:   88 SQLCINTAIVYMHRFYAFHSFTHFHRNSMASASLFLAAKVEEQPRKLEHVIRAANKCLPPTTEQNYAELAQELVFNENVLLQTLGFDVAIDHPHTHVVRTCQLVKACKDLAQTSYFLASNSLHLTSMCLQYRPTVVACFCIYLACKWSRWEIPQSTEGKHWFYYVDKTVSLDLLKQLTDEFIAIYEKSPARLK 280
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Zebrafish
Match: ccnt1 (cyclin T1 [Source:ZFIN;Acc:ZDB-GENE-030131-6397])

HSP 1 Score: 94.3597 bits (233), Expect = 1.084e-20
Identity = 53/199 (26.63%), Postives = 104/199 (52.26%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLK 737
            SQ  I+  I+YMH  ++  +  +     +A  +LFL+ K +++  +++ +++     L    PS + + + Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY+   VA + I++A KW N+   V  D KHW+Q++DP++    + +L+H FL++ ++ P+ LK
Sbjct:   58 SQLTINTAIVYMHRFYMVQSFTRFHRNVIAPAALFLAAKVEEQPRKLEHVIKVTHACLNPQDPSPDTRSDTYLQQAQDLVILESIILQTLGFEITIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYSPPIVACVCIHLACKWSNWEIPVSTDGKHWWQYVDPTVTLELLDELTHEFLQILEKTPSRLK 256
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Zebrafish
Match: ccnt2b (cyclin T2b [Source:ZFIN;Acc:ZDB-GENE-030131-183])

HSP 1 Score: 84.7297 bits (208), Expect = 1.631e-17
Identity = 56/206 (27.18%), Postives = 102/206 (49.51%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMH-----NIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH     N F K ++  I P      +LFL+ K +++  +++ +++     L    P  + K   Y+        LE  V+   G  + + HP+  + +     +   D   +  F+ T+ LH T F +Q+    VA + I++A KW N+   V  D KHW++++D ++    + DL+H FL++ ++ P+ LK I
Sbjct:   55 SQLTINTAIVYMHRFYMLNSFTKFHRNIISP-----TTLFLAAKVEEQPRKLEHVIKVAHACLNPHDPPLDSKSSAYLQQAQELVLLETIVLQTLGFEITIEHPHTDVVRCTQLVRASKDLAQTSYFMATNSLHLTTFCLQHKPTVVACVCIHLACKWSNWEIPVSSDGKHWWEYVDRAVTLQLLDDLTHEFLQILEKTPSRLKRI 255
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Zebrafish
Match: ccnt2a (cyclin T2a [Source:ZFIN;Acc:ZDB-GENE-030131-5779])

HSP 1 Score: 83.1889 bits (204), Expect = 5.628e-17
Identity = 52/201 (25.87%), Postives = 101/201 (50.25%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  K     ++  +LFL+ K +++  +++ +++     L    P  + K   Y+        LE  V+   G  + + HP+  + K     +   D   +  F+ T+ LH T F +Q+    +A + I++A KW N+   V  D KHW++++D S+    + +L+H FL++ ++ P+ LK I
Sbjct:   54 SQLTINTAIVYMHRFYMYHSFTKFHRNIISPTTLFLAAKVEEQPRKLEHVIKVAHACLNPQEPPLDTKSNAYLQQAQELVILETIVLQTLGFEITIEHPHTDVVKCSQLVRASKDLAQTSYFMATNSLHLTTFCLQHKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDNSVTLELLDELTHEFLQILEKTPSRLKRI 254
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Zebrafish
Match: ccnt2a (cyclin T2a [Source:ZFIN;Acc:ZDB-GENE-030131-5779])

HSP 1 Score: 83.1889 bits (204), Expect = 5.729e-17
Identity = 52/201 (25.87%), Postives = 101/201 (50.25%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  K     ++  +LFL+ K +++  +++ +++     L    P  + K   Y+        LE  V+   G  + + HP+  + K     +   D   +  F+ T+ LH T F +Q+    +A + I++A KW N+   V  D KHW++++D S+    + +L+H FL++ ++ P+ LK I
Sbjct:   54 SQLTINTAIVYMHRFYMYHSFTKFHRNIISPTTLFLAAKVEEQPRKLEHVIKVAHACLNPQEPPLDTKSNAYLQQAQELVILETIVLQTLGFEITIEHPHTDVVKCSQLVRASKDLAQTSYFMATNSLHLTTFCLQHKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDNSVTLELLDELTHEFLQILEKTPSRLKRI 254
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Zebrafish
Match: ccnt2b (cyclin T2b [Source:ZFIN;Acc:ZDB-GENE-030131-183])

HSP 1 Score: 79.337 bits (194), Expect = 1.015e-15
Identity = 58/218 (26.61%), Postives = 107/218 (49.08%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMH-----NIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKK----VHNKYKFDDDFICSVS--------FICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH     N F K ++  I P      +LFL+ K +++  +++ +++     L    P  + K   Y+        LE  V+   G  + + HP+  + +    V  + ++ +  + S S        F+ T+ LH T F +Q+    VA + I++A KW N+   V  D KHW++++D ++    + DL+H FL++ ++ P+ LK I
Sbjct:   55 SQLTINTAIVYMHRFYMLNSFTKFHRNIISP-----TTLFLAAKVEEQPRKLEHVIKVAHACLNPHDPPLDSKSSAYLQQAQELVLLETIVLQTLGFEITIEHPHTDVVRCTQLVRGRNRWTETKLMSSSKDLAQTSYFMATNSLHLTTFCLQHKPTVVACVCIHLACKWSNWEIPVSSDGKHWWEYVDRAVTLQLLDDLTHEFLQILEKTPSRLKRI 267
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Xenopus
Match: CCNT1 (cyclin T1 [Source:NCBI gene;Acc:100170179])

HSP 1 Score: 88.5817 bits (218), Expect = 1.350e-18
Identity = 55/202 (27.23%), Postives = 104/202 (51.49%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIID-LSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+Y+H  ++  +  +     V   +LFL+ K +++  +++ ++      L  L P+ + + E Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    VA + I++A KW N+   V  D K W++++D ++ T K++D L+H FL++ ++ PN LK I
Sbjct:   64 SQLTINTAIVYVHRFYMVQSFTRFHRNSVGPAALFLAAKVEEQPRKLEHVIRVAHACLSPLEPAPDTRSEAYLQQAQDLVILESIILQTLGFEITIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKPWWEYVDVTV-TLKLLDELTHEFLQILEKTPNRLKRI 264
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Xenopus
Match: CCNT1 (cyclin T1 [Source:NCBI gene;Acc:100170179])

HSP 1 Score: 88.5817 bits (218), Expect = 1.381e-18
Identity = 55/202 (27.23%), Postives = 104/202 (51.49%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIID-LSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+Y+H  ++  +  +     V   +LFL+ K +++  +++ ++      L  L P+ + + E Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    VA + I++A KW N+   V  D K W++++D ++ T K++D L+H FL++ ++ PN LK I
Sbjct:   50 SQLTINTAIVYVHRFYMVQSFTRFHRNSVGPAALFLAAKVEEQPRKLEHVIRVAHACLSPLEPAPDTRSEAYLQQAQDLVILESIILQTLGFEITIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKPWWEYVDVTV-TLKLLDELTHEFLQILEKTPNRLKRI 250
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Xenopus
Match: CCNT2 (cyclin T2 [Source:NCBI gene;Acc:100488125])

HSP 1 Score: 87.8113 bits (216), Expect = 2.290e-18
Identity = 53/201 (26.37%), Postives = 103/201 (51.24%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  K     ++  +LFL+ K +++  +++ +++     L  + P  + K E Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    +A + I++A KW N+   V  D KHW++++D S+    + +L+H FL++ ++ P+ LK I
Sbjct:   55 SQLTINTAIVYMHRFYMHHSFTKYHRNVMSPTALFLAAKVEEQPRKLEHVIKVAHACLNPVEPQLDTKSEGYLQQAQELVTLETVLLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDQSVTLELLDELTHEFLQILEKTPSRLKRI 255
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Xenopus
Match: CCNT2 (cyclin T2 [Source:NCBI gene;Acc:100488125])

HSP 1 Score: 87.8113 bits (216), Expect = 2.381e-18
Identity = 53/201 (26.37%), Postives = 103/201 (51.24%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  K     ++  +LFL+ K +++  +++ +++     L  + P  + K E Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    +A + I++A KW N+   V  D KHW++++D S+    + +L+H FL++ ++ P+ LK I
Sbjct:   55 SQLTINTAIVYMHRFYMHHSFTKYHRNVMSPTALFLAAKVEEQPRKLEHVIKVAHACLNPVEPQLDTKSEGYLQQAQELVTLETVLLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDQSVTLELLDELTHEFLQILEKTPSRLKRI 255
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Xenopus
Match: CCNT2 (cyclin T2 [Source:NCBI gene;Acc:100488125])

HSP 1 Score: 85.5001 bits (210), Expect = 1.394e-17
Identity = 51/198 (25.76%), Postives = 101/198 (51.01%), Query Frame = 3 
Query:  174 VIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
             I+  I+YMH  ++  +  K     ++  +LFL+ K +++  +++ +++     L  + P  + K E Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    +A + I++A KW N+   V  D KHW++++D S+    + +L+H FL++ ++ P+ LK I
Sbjct:    8 TINTAIVYMHRFYMHHSFTKYHRNVMSPTALFLAAKVEEQPRKLEHVIKVAHACLNPVEPQLDTKSEGYLQQAQELVTLETVLLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDQSVTLELLDELTHEFLQILEKTPSRLKRI 205
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Mouse
Match: Ccnt2 (cyclin T2 [Source:MGI Symbol;Acc:MGI:1920199])

HSP 1 Score: 89.7373 bits (221), Expect = 3.685e-19
Identity = 57/206 (27.67%), Postives = 104/206 (50.49%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNI-----FVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH       F K N+  I P      +LFL+ K +++  +++ +++     L  L P  + K + Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    +A + I++A KW N+   V  D KHW++++DP++    + +L+H FL++ ++ P+ LK I
Sbjct:   54 SQLTINTAIVYMHRFYMHHSFTKFNRNIISP-----TALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVLLETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPSRLKRI 254
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Mouse
Match: Ccnt2 (cyclin T2 [Source:MGI Symbol;Acc:MGI:1920199])

HSP 1 Score: 89.3521 bits (220), Expect = 5.374e-19
Identity = 57/206 (27.67%), Postives = 104/206 (50.49%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNI-----FVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYI------TCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH       F K N+  I P      +LFL+ K +++  +++ +++     L  L P  + K + Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    +A + I++A KW N+   V  D KHW++++DP++    + +L+H FL++ ++ P+ LK I
Sbjct:   54 SQLTINTAIVYMHRFYMHHSFTKFNRNIISP-----TALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVLLETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPSRLKRI 254
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Mouse
Match: Ccnt1 (cyclin T1 [Source:MGI Symbol;Acc:MGI:1328363])

HSP 1 Score: 85.5001 bits (210), Expect = 1.161e-17
Identity = 57/205 (27.80%), Postives = 102/205 (49.76%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKY--QDKRIEMKLLVEKVLILGKLSPSKNL---KIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  +     +A  +LFL+ K   Q K++E  + V        L P ++L   + E Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    VA + I++A KW N+   V  D KHW++++D ++    + +L+H FL++ ++ P+ LK I
Sbjct:   55 SQLTINTAIVYMHRFYMIQSFTQFHRYSMAPAALFLAAKVEEQPKKLEHVIKVAHTC----LHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPSRLKRI 255
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Mouse
Match: Ccnt1 (cyclin T1 [Source:MGI Symbol;Acc:MGI:1328363])

HSP 1 Score: 85.5001 bits (210), Expect = 1.161e-17
Identity = 57/205 (27.80%), Postives = 102/205 (49.76%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKY--QDKRIEMKLLVEKVLILGKLSPSKNL---KIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  +     +A  +LFL+ K   Q K++E  + V        L P ++L   + E Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    VA + I++A KW N+   V  D KHW++++D ++    + +L+H FL++ ++ P+ LK I
Sbjct:   55 SQLTINTAIVYMHRFYMIQSFTQFHRYSMAPAALFLAAKVEEQPKKLEHVIKVAHTC----LHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPSRLKRI 255
[Close]
BLAST of CYCLIN domain-containing protein vs. UniProt/SwissProt
Match: sp|O60583|CCNT2_HUMAN (Cyclin-T2 OS=Homo sapiens OX=9606 GN=CCNT2 PE=1 SV=2)

HSP 1 Score: 92.0485 bits (227), Expect = 5.546e-19
Identity = 54/201 (26.87%), Postives = 105/201 (52.24%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYI------TCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  K     +++ +LFL+ K +++  +++ +++     L  L P  + K + Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    +A + I++A KW N+   V  D KHW++++DP++    + +L+H FL++ ++ PN LK I
Sbjct:   54 SQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPNRLKKI 254
[Close]
BLAST of CYCLIN domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7TQK0|CCNT2_MOUSE (Cyclin-T2 OS=Mus musculus OX=10090 GN=Ccnt2 PE=1 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 3.759e-18
Identity = 57/206 (27.67%), Postives = 104/206 (50.49%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNI-----FVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYI------TCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH       F K N+  I P      +LFL+ K +++  +++ +++     L  L P  + K + Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    +A + I++A KW N+   V  D KHW++++DP++    + +L+H FL++ ++ P+ LK I
Sbjct:   54 SQLTINTAIVYMHRFYMHHSFTKFNRNIISP-----TALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVLLETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPSRLKRI 254
[Close]
BLAST of CYCLIN domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8HXN7|CCNT1_PANTR (Cyclin-T1 OS=Pan troglodytes OX=9598 GN=CCNT1 PE=2 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 8.624e-18
Identity = 59/205 (28.78%), Postives = 102/205 (49.76%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKY--QDKRIEMKLLVEKVLILGKLSPSKNL---KIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  +     VA  +LFL+ K   Q K++E  + V        L P ++L   + E Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    VA + I++A KW N+   V  D KHW++++D ++    + +L+H FL++ ++ PN LK I
Sbjct:   54 SQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTC----LHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPNRLKRI 254
[Close]
BLAST of CYCLIN domain-containing protein vs. UniProt/SwissProt
Match: sp|O60563|CCNT1_HUMAN (Cyclin-T1 OS=Homo sapiens OX=9606 GN=CCNT1 PE=1 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 8.954e-18
Identity = 59/205 (28.78%), Postives = 102/205 (49.76%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTK--YQDKRIEMKLLVEKVLILGKLSPSKNL---KIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  +     VA  +LFL+ K   Q K++E  + V        L P ++L   + E Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    VA + I++A KW N+   V  D KHW++++D ++    + +L+H FL++ ++ PN LK I
Sbjct:   55 SQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTC----LHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPNRLKRI 255
[Close]
BLAST of CYCLIN domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9XT26|CCNT1_HORSE (Cyclin-T1 OS=Equus caballus OX=9796 GN=CCNT1 PE=1 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 1.038e-17
Identity = 59/205 (28.78%), Postives = 102/205 (49.76%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTK--YQDKRIEMKLLVEKVLILGKLSPSKNL---KIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  +     VA  +LFL+ K   Q K++E  + V        L P ++L   + E Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    VA + I++A KW N+   V  D KHW++++D ++    + +L+H FL++ ++ PN LK I
Sbjct:   55 SQLTINTAIVYMHRFYMIQSFTQFHRNSVAPAALFLAAKVEEQPKKLEHVIKVAHAC----LHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPNRLKRI 255
[Close]
BLAST of CYCLIN domain-containing protein vs. TrEMBL
Match: H3BDK5 (Cyclin T1 OS=Latimeria chalumnae OX=7897 GN=CCNT1 PE=3 SV=1)

HSP 1 Score: 97.0561 bits (240), Expect = 3.047e-18
Identity = 56/201 (27.86%), Postives = 106/201 (52.74%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  +     VA   LFL+ K +++  +++ +++     L    PS +++ E Y+        LE+ ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY+   VA + I++A KW N+   V  D KHW++++DP++    + +L+H FL++ ++ PN LK I
Sbjct:   59 SQLTINTAIVYMHRFYMIQSFTRFHRNAVAPAVLFLAAKVEEQPRKLEHVIKVTHACLNPQEPSPDIRSEAYLQQAQDLVILENIILQTLGFEITIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYSPPIVACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPNRLKRI 259
[Close]
BLAST of CYCLIN domain-containing protein vs. TrEMBL
Match: Q6PFP0 (Si:dkey-18f23.10 protein (Fragment) OS=Danio rerio OX=7955 GN=ccnt1 PE=2 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 1.905e-17
Identity = 53/199 (26.63%), Postives = 104/199 (52.26%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLK 737
            SQ  I+  I+YMH  ++  +  +     +A  +LFL+ K +++  +++ +++     L    PS + + + Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY+   VA + I++A KW N+   V  D KHW+Q++DP++    + +L+H FL++ ++ P+ LK
Sbjct:   67 SQLTINTAIVYMHRFYMVQSFTRFHRDVIAPAALFLAAKVEEQPRKLEHVIKVTHACLNPQDPSPDTRSDTYLQQAQDLVILESIILQTLGFEITIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYSPPIVACVCIHLACKWSNWEIPVSTDGKHWWQYVDPTVTLELLDELTHEFLQILEKTPSRLK 265
[Close]
BLAST of CYCLIN domain-containing protein vs. TrEMBL
Match: Q803K9 (Si:dkey-18f23.10 protein (Fragment) OS=Danio rerio OX=7955 GN=ccnt1 PE=2 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 2.201e-17
Identity = 53/199 (26.63%), Postives = 104/199 (52.26%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLK 737
            SQ  I+  I+YMH  ++  +  +     +A  +LFL+ K +++  +++ +++     L    PS + + + Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY+   VA + I++A KW N+   V  D KHW+Q++DP++    + +L+H FL++ ++ P+ LK
Sbjct:   63 SQLTINTAIVYMHRFYMVQSFTRFHRNVIAPAALFLAAKVEEQPRKLEHVIKVTHACLNPQDPSPDTRSDTYLQQAQDLVILESIILQTLGFEITIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYSPPIVACVCIHLACKWSNWEIPVSTDGKHWWQYVDPTVTLELLDELTHEFLQILEKTPSRLK 261
[Close]
BLAST of CYCLIN domain-containing protein vs. TrEMBL
Match: B8A521 (Cyclin T1 OS=Danio rerio OX=7955 GN=ccnt1 PE=3 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 2.426e-17
Identity = 53/199 (26.63%), Postives = 104/199 (52.26%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLK 737
            SQ  I+  I+YMH  ++  +  +     +A  +LFL+ K +++  +++ +++     L    PS + + + Y+        LE  ++   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY+   VA + I++A KW N+   V  D KHW+Q++DP++    + +L+H FL++ ++ P+ LK
Sbjct:   58 SQLTINTAIVYMHRFYMVQSFTRFHRNVIAPAALFLAAKVEEQPRKLEHVIKVTHACLNPQDPSPDTRSDTYLQQAQDLVILESIILQTLGFEITIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYSPPIVACVCIHLACKWSNWEIPVSTDGKHWWQYVDPTVTLELLDELTHEFLQILEKTPSRLK 256
[Close]
BLAST of CYCLIN domain-containing protein vs. TrEMBL
Match: A0A4U5UPU2 (Cyclin-T1 OS=Collichthys lucidus OX=240159 GN=D9C73_010667 PE=3 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 3.261e-17
Identity = 52/203 (25.62%), Postives = 107/203 (52.71%), Query Frame = 3 
Query:  159 FRSQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            +RSQ  I+  I+YMH  ++  +  +     ++  +LFL+ K +++  +++ +++     L    PS +++ + Y+        LE  ++      + + HP+  + K     +   D   +  F+ T+ LH T F +QY+   VA + I++A KW N+   V  D KHW++++DP++    + +L+H FL++ ++ P+ LK I
Sbjct:   11 WRSQLTINTAIVYMHRFYMVQSFTRFHRNVISPAALFLAAKVEEQPRKLEHVIKVAHACLNPQEPSPDVRSDAYLQQAQDLVILESIILQTLAFEITIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYSPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPSRLKRI 213
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Cavefish
Match: ccnt2b (cyclin-T2-like [Source:NCBI gene;Acc:103028284])

HSP 1 Score: 88.1965 bits (217), Expect = 1.008e-18
Identity = 61/207 (29.47%), Postives = 106/207 (51.21%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMH-----NIFVKLNQKKIQPIYVAAVSLFLSTKY--QDKRIEMKLLVEKVLILGKLSP---SKN--LKIEYYITCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIID-LSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH     N F K ++  I P      +LFL+ K   Q +++E  + V    +  +  P   S N  L+    +  LE  V+   G  + + HP+  + +     +   D   +  F+ T+ LH T F +QY    VA + I++A KW N+   +  D KHW++++DP++ T +++D L+H FL++ ++ P+ LK I
Sbjct:   69 SQLTINTAIVYMHRFYMLNSFTKFHRNIISP-----TTLFLAAKVEEQPRKLEHVIKVSHACLNPQEPPLDTSSNVYLQQAQELVLLETIVLQTLGFEITIEHPHTDVVRCSQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVVACVCIHLACKWSNWEIPISSDGKHWWEYLDPTV-TLQLLDQLTHEFLQILEKTPSRLKRI 269
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Cavefish
Match: ccnt1 (cyclin T1 [Source:ZFIN;Acc:ZDB-GENE-030131-6397])

HSP 1 Score: 83.9593 bits (206), Expect = 2.697e-17
Identity = 53/203 (26.11%), Postives = 104/203 (51.23%), Query Frame = 3 
Query:  159 FRSQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYITCLEHTVIGLFGTIMNMI------HPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
              SQ  I+ GI+YMH  ++  +        +A  +LFL++K +++  +++ ++      L    P+ + + + Y+      ++ L   I+  +      HP+  + K     +  D  +   S+   + LH T F +QY+   VA + I++A KW N+   V  D KHW++++D  + T +++DL+H FL++ ++ PN LK I
Sbjct:   55 LNSQLSINTGIVYMHRFYMVQSFTLFHRNVIAPAALFLASKVEEQPRKLEHVIRVAHACLNPQDPTLDSRSDTYVQ-QSQDLVALESIILQTLFDITIDHPHSHVVKCTQLVRSKD--LAQTSYFMATNLHLTTFCLQYSPTVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDSKV-TLELLDLTHEFLQILEKTPNRLKRI 253
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Cavefish
Match: ccnt2b (cyclin-T2-like [Source:NCBI gene;Acc:103028284])

HSP 1 Score: 81.2629 bits (199), Expect = 1.670e-16
Identity = 61/213 (28.64%), Postives = 106/213 (49.77%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMH-----NIFVKLNQKKIQPIYVAAVSLFLSTKY--QDKRIEMKLLVEKVLILGKLSP---SKN--LKIEYYITCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKF------DDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIID-LSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH     N F K ++  I P      +LFL+ K   Q +++E  + V    +  +  P   S N  L+    +  LE  V+   G  + + HP+  + +     +         D   +  F+ T+ LH T F +QY    VA + I++A KW N+   +  D KHW++++DP++ T +++D L+H FL++ ++ P+ LK I
Sbjct:   65 SQLTINTAIVYMHRFYMLNSFTKFHRNIISP-----TTLFLAAKVEEQPRKLEHVIKVSHACLNPQEPPLDTSSNVYLQQAQELVLLETIVLQTLGFEITIEHPHTDVVRCSQLVRGRCFHLSSKDLAQTSYFMATNSLHLTTFCLQYKPTVVACVCIHLACKWSNWEIPISSDGKHWWEYLDPTV-TLQLLDQLTHEFLQILEKTPSRLKRI 271
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Cavefish
Match: ccnt2a (cyclin T2 [Source:NCBI gene;Acc:103023729])

HSP 1 Score: 73.559 bits (179), Expect = 6.676e-14
Identity = 48/201 (23.88%), Postives = 99/201 (49.25%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDL-VKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  K     ++  +LFL+ K +++  +++ +++     L    P  + K   Y+        LE  V+   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    +A + I++  KW+  ++ +  D K W++++D S+    + +L+  FL++ ++ P+ LK I
Sbjct:   54 SQLTINTAIVYMHRFYMYHSFTKFHRNIISPTTLFLAAKVEEQPRKLEHVIKVAHACLNPQEPPLDAKSNAYLQQAQELVILETIVLQTLGFEITIEHPHTDVVKCSQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLVCKWSKREIPLSTDGKSWWEYVDNSVTIELLDELTTEFLQILEKTPSRLKKI 254
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Cavefish
Match: ccnt2a (cyclin T2 [Source:NCBI gene;Acc:103023729])

HSP 1 Score: 73.1738 bits (178), Expect = 8.068e-14
Identity = 48/201 (23.88%), Postives = 99/201 (49.25%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDL-VKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  K     ++  +LFL+ K +++  +++ +++     L    P  + K   Y+        LE  V+   G  + + HP+  + K     +   D   +  F+ T+ LH T F +QY    +A + I++  KW+  ++ +  D K W++++D S+    + +L+  FL++ ++ P+ LK I
Sbjct:   54 SQLTINTAIVYMHRFYMYHSFTKFHRNIISPTTLFLAAKVEEQPRKLEHVIKVAHACLNPQEPPLDAKSNAYLQQAQELVILETIVLQTLGFEITIEHPHTDVVKCSQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLVCKWSKREIPLSTDGKSWWEYVDNSVTIELLDELTTEFLQILEKTPSRLKKI 254
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003616.1 (pep scaffold:Pmarinus_7.0:GL476475:418210:425326:1 gene:ENSPMAG00000003277.1 transcript:ENSPMAT00000003616.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 83.1889 bits (204), Expect = 1.069e-17
Identity = 53/202 (26.24%), Postives = 99/202 (49.01%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTK--YQDKRIEMKLLVEKVLILGKLSPSKNLKIEYYITCL------EHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++     K     ++  +LFL+ K   Q +++E  + V    +  + +P  + K + Y+         EH ++   G  + + HP+ ++ K     +   D   +  F+ T+ LH T F +Q+    VA + I++A KW N+   V  D K W++++D  +    +  L+H FL++ ++ PN LK I
Sbjct:   45 SQLTINTAIVYMHRFYMLQTFSKFHRNAISPAALFLAAKVEEQPRKLEHVIKVAHACLNPQEAP-LDTKSDAYLQQAQDLVMNEHVMLQTLGFEITIDHPHTYVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQHKPTVVACVCIHLACKWSNWEIPVSSDGKPWWEYVDNGVSMNLLDALTHEFLQILEKTPNRLKRI 245
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Nematostella
Match: EDO42905 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S058])

HSP 1 Score: 77.0258 bits (188), Expect = 2.425e-16
Identity = 53/200 (26.50%), Postives = 100/200 (50.00%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYITCL------EHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIID-LSHHFLKVFKEIPNNLK 737
            SQ  I+  I+YMH  ++    +K     +A   LFLS K +++  +++ ++      L +  P  N + E Y+         E  ++   G  + + HP+ ++ K     +   D   +  F+ T+ LH T   +Q+    VA   I++A KW NY      DHK+W+Q+I+P++ T K++D ++  F+ + ++ P+ LK
Sbjct:   56 SQLTINTSIVYMHRFYMCHPFQKFHRHAMAPCCLFLSAKVEEQPRKLEHVIRVAHACLHRDGPPLNPESEEYLQQAQDLIENESILLQTLGFEVTVHHPHTYVVKGIQLVRASKDLGQASYFMATNSLHLTTLCLQFKPPVVACACIHLACKWCNYEIPQSSDHKYWWQYINPTV-TKKLLDEIAQEFVNIMEKCPSRLK 254
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Medaka
Match: ccnt2a (cyclin T2 [Source:NCBI gene;Acc:101159477])

HSP 1 Score: 83.9593 bits (206), Expect = 2.631e-17
Identity = 52/201 (25.87%), Postives = 101/201 (50.25%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYI------TCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  K     ++  +LFL+ K +++  +++ +++     L    P  + K   Y+        LE  V+   G  + + HP+  + K     +   D   +  F+ T+ LH T F +Q+    +A + I++A KW N+   V  D KHW++++D S+    + +L+H FL++ ++ P+ LK I
Sbjct:  113 SQLTINTAIVYMHRFYMHHSFTKFHRNIISPTTLFLAAKVEEQPRKLEHVIKVAHACLNPQEPPLDTKSNAYLQQAQELVILESIVLQTLGFEITIDHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQHKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDNSVTLELLDELTHEFLQILEKTPSRLKRI 313
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Medaka
Match: ccnt2a (cyclin T2 [Source:NCBI gene;Acc:101159477])

HSP 1 Score: 83.9593 bits (206), Expect = 2.870e-17
Identity = 52/201 (25.87%), Postives = 101/201 (50.25%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ  I+  I+YMH  ++  +  K     ++  +LFL+ K +++  +++ +++     L    P  + K   Y+        LE  V+   G  + + HP+  + K     +   D   +  F+ T+ LH T F +Q+    +A + I++A KW N+   V  D KHW++++D S+    + +L+H FL++ ++ P+ LK I
Sbjct:  113 SQLTINTAIVYMHRFYMHHSFTKFHRNIISPTTLFLAAKVEEQPRKLEHVIKVAHACLNPQEPPLDTKSNAYLQQAQELVILESIVLQTLGFEITIDHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQHKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDNSVTLELLDELTHEFLQILEKTPSRLKRI 313
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Medaka
Match: ccnt2b (cyclin-T2 [Source:NCBI gene;Acc:101157196])

HSP 1 Score: 81.6481 bits (200), Expect = 1.375e-16
Identity = 49/201 (24.38%), Postives = 102/201 (50.75%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKV-LILGKLSPSKNLKIEYY------ITCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVI 743
            SQ +I+  I+YMH  ++  +  K     ++  +LFL+ K +++  +++ +++     +    P+ + K   +      +  LE  V+   G  + + HP+  + +     +   D   +  F+ T+ LH T F ++Y    VA + I++A KW N+   V  D KHW++++D ++    + +L+H FL++ +  P+ LK I
Sbjct:   54 SQLIINTAIVYMHRFYMIHSFTKFHRNIISQTTLFLAAKVEEQPRKLEHVIKMAHAFINPQEPALDTKSSAFQLQAHELVVLESIVLQTLGFEITVDHPHTDVVRCSQLVRASRDLAQTSYFMATNSLHLTTFCLEYRPTVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDRTVTLQLLDELTHEFLQILERTPSKLKRI 254
[Close]
BLAST of CYCLIN domain-containing protein vs. Ensembl Medaka
Match: ccnt1 (cyclin T1 [Source:NCBI gene;Acc:101175653])

HSP 1 Score: 73.559 bits (179), Expect = 1.313e-14
Identity = 50/191 (26.18%), Postives = 93/191 (48.69%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLN----QKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKVLILGKLSPSKNLKIEYYIT------CLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKW-NYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFL 704
            SQ  I+  I+YMH  ++  +     + +  I  AA+ L    + Q +++E  + V     L    PS +++ + Y+T       LE  ++      + + HP+  + K     +   D   +  F+ T+ LH T F +QY    VA + I++A KW N+   V  D KHW++++DP++ T +++D +   L
Sbjct:   56 SQLTINTAIVYMHRFYMIQSFTRFHRNVSVISPAALFLAAKVEEQPRKLEHVIKVAHA-CLNPQEPSPDVRSDAYLTQAQDLVILESIILQTLAFEITIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYCPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTV-TLELLDGTSQIL 244
[Close]
BLAST of CYCLIN domain-containing protein vs. Planmine SMEST
Match: SMESG000066582.1 (SMESG000066582.1)

HSP 1 Score: 535.028 bits (1377), Expect = 0.000e+0
Identity = 287/287 (100.00%), Postives = 287/287 (100.00%), Query Frame = 3 
Query:  162 RSQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKVLILGKLSPSKNLKIEYYITCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVIAFEQKVKENSSMLAXXXXXXXXXXXPKKRKIISKDEYTKRSQETNYSNYRAVEHXXXXXXXXXXXXQFHPQKRSDLNRPESKLELTPESYMDF 1022
            RSQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKVLILGKLSPSKNLKIEYYITCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVIAFEQKVKENSSMLANNNINNNNNQNPKKRKIISKDEYTKRSQETNYSNYRAVEHKTKTNSTISSSSQFHPQKRSDLNRPESKLELTPESYMDF
Sbjct:   25 RSQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKVLILGKLSPSKNLKIEYYITCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVIAFEQKVKENSSMLANNNINNNNNQNPKKRKIISKDEYTKRSQETNYSNYRAVEHKTKTNSTISSSSQFHPQKRSDLNRPESKLELTPESYMDF 311

HSP 2 Score: 54.299 bits (129), Expect = 4.886e-8
Identity = 25/25 (100.00%), Postives = 25/25 (100.00%), Query Frame = 1 
Query:   49 MSIEKLKRQIVCATLIQELGVLCNR 123
            MSIEKLKRQIVCATLIQELGVLCNR
Sbjct:    1 MSIEKLKRQIVCATLIQELGVLCNR 25
[Close]
BLAST of CYCLIN domain-containing protein vs. Planmine SMEST
Match: SMESG000066582.1 (SMESG000066582.1)

HSP 1 Score: 508.834 bits (1309), Expect = 0.000e+0
Identity = 275/275 (100.00%), Postives = 275/275 (100.00%), Query Frame = 3 
Query:  198 MHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKVLILGKLSPSKNLKIEYYITCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVIAFEQKVKENSSMLAXXXXXXXXXXXPKKRKIISKDEYTKRSQETNYSNYRAVEHXXXXXXXXXXXXQFHPQKRSDLNRPESKLELTPESYMDF 1022
            MHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKVLILGKLSPSKNLKIEYYITCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVIAFEQKVKENSSMLANNNINNNNNQNPKKRKIISKDEYTKRSQETNYSNYRAVEHKTKTNSTISSSSQFHPQKRSDLNRPESKLELTPESYMDF
Sbjct:    1 MHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKVLILGKLSPSKNLKIEYYITCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVIAFEQKVKENSSMLANNNINNNNNQNPKKRKIISKDEYTKRSQETNYSNYRAVEHKTKTNSTISSSSQFHPQKRSDLNRPESKLELTPESYMDF 275
[Close]
BLAST of CYCLIN domain-containing protein vs. Planmine SMEST
Match: SMESG000066586.1 (SMESG000066586.1)

HSP 1 Score: 109.383 bits (272), Expect = 7.816e-27
Identity = 60/197 (30.46%), Postives = 113/197 (57.36%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKVLIL-GKLSPSKNLKIEYYITCLEHTVIGLFG-TIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVIAF 749
            SQ +I+  I+YMH ++ K +  +++P+YVA  S +L++K +D   ++  +V+ +  L GK   S   +I   +  LE  ++   G   ++ +HP+  I  +  KY   + FI +  FICTS+LH T   ++++++ +A  A+Y+A+KW+YI+L   + + WF  I   +  + +  +S  FL ++ + P  LK+ AF
Sbjct:   32 SQLLINTAIVYMHKLYEKFSYNELKPVYVAMTSFYLASKSEDCARKLNDIVKTMYQLSGKQIDSNFERIVSAVHALESIMLMSVGFPRLDFVHPHIVIMDIVKKYDIHNGFIDTAYFICTSMLHLTTLCVRHSTQEIAAAALYVASKWDYIELKDINLRPWFSSISSGLTISVLQKMSKEFLDIYVKTPIKLKLKAF 228
[Close]
BLAST of CYCLIN domain-containing protein vs. Planmine SMEST
Match: SMESG000066586.1 (SMESG000066586.1)

HSP 1 Score: 109.383 bits (272), Expect = 9.904e-27
Identity = 60/197 (30.46%), Postives = 113/197 (57.36%), Query Frame = 3 
Query:  165 SQEVIDVGIIYMHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKVLIL-GKLSPSKNLKIEYYITCLEHTVIGLFG-TIMNMIHPNFFIKKVHNKYKFDDDFICSVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDLVKYDHKHWFQFIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVIAF 749
            SQ +I+  I+YMH ++ K +  +++P+YVA  S +L++K +D   ++  +V+ +  L GK   S   +I   +  LE  ++   G   ++ +HP+  I  +  KY   + FI +  FICTS+LH T   ++++++ +A  A+Y+A+KW+YI+L   + + WF  I   +  + +  +S  FL ++ + P  LK+ AF
Sbjct:   32 SQLLINTAIVYMHKLYEKFSYNELKPVYVAMTSFYLASKSEDCARKLNDIVKTMYQLSGKQIDSNFERIVSAVHALESIMLMSVGFPRLDFVHPHIVIMDIVKKYDIHNGFIDTAYFICTSMLHLTTLCVRHSTQEIAAAALYVASKWDYIELKDINLRPWFSSISSGLTISVLQKMSKEFLDIYVKTPIKLKLKAF 228
The following BLAST results are available for this feature:
BLAST of CYCLIN domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CCNT29.340e-2026.87cyclin T2 [Source:HGNC Symbol;Acc:HGNC:1600][more]
CCNT21.155e-1926.87cyclin T2 [Source:HGNC Symbol;Acc:HGNC:1600][more]
CCNT11.864e-1828.78cyclin T1 [Source:HGNC Symbol;Acc:HGNC:1599][more]
CCNT23.171e-1437.50cyclin T2 [Source:HGNC Symbol;Acc:HGNC:1600][more]
CCNT22.054e-1237.84cyclin T2 [Source:HGNC Symbol;Acc:HGNC:1600][more]
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BLAST of CYCLIN domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of CYCLIN domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CycT2.750e-1222.28gene:FBgn0025455 transcript:FBtr0333124[more]
CycT2.750e-1222.28gene:FBgn0025455 transcript:FBtr0075205[more]
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BLAST of CYCLIN domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ccnt11.084e-2026.63cyclin T1 [Source:ZFIN;Acc:ZDB-GENE-030131-6397][more]
ccnt2b1.631e-1727.18cyclin T2b [Source:ZFIN;Acc:ZDB-GENE-030131-183][more]
ccnt2a5.628e-1725.87cyclin T2a [Source:ZFIN;Acc:ZDB-GENE-030131-5779][more]
ccnt2a5.729e-1725.87cyclin T2a [Source:ZFIN;Acc:ZDB-GENE-030131-5779][more]
ccnt2b1.015e-1526.61cyclin T2b [Source:ZFIN;Acc:ZDB-GENE-030131-183][more]
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BLAST of CYCLIN domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CCNT11.350e-1827.23cyclin T1 [Source:NCBI gene;Acc:100170179][more]
CCNT11.381e-1827.23cyclin T1 [Source:NCBI gene;Acc:100170179][more]
CCNT22.290e-1826.37cyclin T2 [Source:NCBI gene;Acc:100488125][more]
CCNT22.381e-1826.37cyclin T2 [Source:NCBI gene;Acc:100488125][more]
CCNT21.394e-1725.76cyclin T2 [Source:NCBI gene;Acc:100488125][more]
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BLAST of CYCLIN domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Ccnt23.685e-1927.67cyclin T2 [Source:MGI Symbol;Acc:MGI:1920199][more]
Ccnt25.374e-1927.67cyclin T2 [Source:MGI Symbol;Acc:MGI:1920199][more]
Ccnt11.161e-1727.80cyclin T1 [Source:MGI Symbol;Acc:MGI:1328363][more]
Ccnt11.161e-1727.80cyclin T1 [Source:MGI Symbol;Acc:MGI:1328363][more]
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BLAST of CYCLIN domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O60583|CCNT2_HUMAN5.546e-1926.87Cyclin-T2 OS=Homo sapiens OX=9606 GN=CCNT2 PE=1 SV... [more]
sp|Q7TQK0|CCNT2_MOUSE3.759e-1827.67Cyclin-T2 OS=Mus musculus OX=10090 GN=Ccnt2 PE=1 S... [more]
sp|Q8HXN7|CCNT1_PANTR8.624e-1828.78Cyclin-T1 OS=Pan troglodytes OX=9598 GN=CCNT1 PE=2... [more]
sp|O60563|CCNT1_HUMAN8.954e-1828.78Cyclin-T1 OS=Homo sapiens OX=9606 GN=CCNT1 PE=1 SV... [more]
sp|Q9XT26|CCNT1_HORSE1.038e-1728.78Cyclin-T1 OS=Equus caballus OX=9796 GN=CCNT1 PE=1 ... [more]
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BLAST of CYCLIN domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
H3BDK53.047e-1827.86Cyclin T1 OS=Latimeria chalumnae OX=7897 GN=CCNT1 ... [more]
Q6PFP01.905e-1726.63Si:dkey-18f23.10 protein (Fragment) OS=Danio rerio... [more]
Q803K92.201e-1726.63Si:dkey-18f23.10 protein (Fragment) OS=Danio rerio... [more]
B8A5212.426e-1726.63Cyclin T1 OS=Danio rerio OX=7955 GN=ccnt1 PE=3 SV=... [more]
A0A4U5UPU23.261e-1725.62Cyclin-T1 OS=Collichthys lucidus OX=240159 GN=D9C7... [more]
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BLAST of CYCLIN domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ccnt2b1.008e-1829.47cyclin-T2-like [Source:NCBI gene;Acc:103028284][more]
ccnt12.697e-1726.11cyclin T1 [Source:ZFIN;Acc:ZDB-GENE-030131-6397][more]
ccnt2b1.670e-1628.64cyclin-T2-like [Source:NCBI gene;Acc:103028284][more]
ccnt2a6.676e-1423.88cyclin T2 [Source:NCBI gene;Acc:103023729][more]
ccnt2a8.068e-1423.88cyclin T2 [Source:NCBI gene;Acc:103023729][more]
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BLAST of CYCLIN domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000003616.11.069e-1726.24pep scaffold:Pmarinus_7.0:GL476475:418210:425326:1... [more]
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BLAST of CYCLIN domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of CYCLIN domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO429052.425e-1626.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of CYCLIN domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ccnt2a2.631e-1725.87cyclin T2 [Source:NCBI gene;Acc:101159477][more]
ccnt2a2.870e-1725.87cyclin T2 [Source:NCBI gene;Acc:101159477][more]
ccnt2b1.375e-1624.38cyclin-T2 [Source:NCBI gene;Acc:101157196][more]
ccnt11.313e-1426.18cyclin T1 [Source:NCBI gene;Acc:101175653][more]
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BLAST of CYCLIN domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000066582.14.886e-8100.00SMESG000066582.1[more]
SMESG000066582.10.000e+0100.00SMESG000066582.1[more]
SMESG000066586.17.816e-2730.46SMESG000066586.1[more]
SMESG000066586.19.904e-2730.46SMESG000066586.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30000019 ID=SMED30000019|Name=CYCLIN domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1059bp
AGTTTGTTTAAATAATATAAAATGTAAATATTTTTCATCGGAGTTATTAT
GTCTATTGAAAAATTAAAGCGACAAATCGTTTGTGCAACTTTAATACAAG
AATTAGGTGTATTATGTAACCGGTAAGATTCTTTGAAAATTATTAGAGGA
CTTAATTGTTCAGATCTCAAGAAGTTATAGACGTTGGGATAATATATATG
CATAATATTTTTGTCAAATTGAATCAAAAAAAAATTCAGCCTATTTATGT
TGCAGCGGTTTCTTTATTTTTAAGTACCAAATATCAAGATAAAAGAATTG
AAATGAAATTATTAGTTGAAAAGGTTTTGATACTTGGAAAATTATCTCCG
TCGAAGAATTTAAAGATTGAATATTATATCACTTGTTTAGAGCATACAGT
AATAGGATTATTCGGAACCATTATGAACATGATTCACCCAAATTTCTTTA
TTAAGAAAGTGCACAACAAATATAAATTTGATGATGATTTTATCTGCTCT
GTTAGTTTTATATGTACTTCAATATTACATTACACAGATTTTGTGATTCA
ATACAATTCAGAATATGTAGCAATTATTGCTATTTATATTGCAACGAAAT
GGAATTACATTGATCTTGTTAAATATGACCATAAACACTGGTTTCAGTTC
ATTGACCCATCAATTCAAACCACTAAAATTATTGATTTGAGTCATCACTT
TTTAAAAGTATTTAAAGAAATTCCAAATAATTTAAAAGTTATCGCATTTG
AGCAAAAAGTCAAAGAAAATTCGTCAATGTTAGCAAATAATAATATTAAT
AATAATAATAATCAAAACCCTAAGAAAAGAAAGATTATTAGTAAAGATGA
ATACACAAAAAGGTCTCAGGAAACAAATTATTCAAATTATCGCGCTGTTG
AGCACAAGACCAAGACAAATTCCACAATAAGCAGCAGCAGCCAATTCCAT
CCGCAGAAAAGGTCGGATTTAAATCGACCCGAATCAAAGTTGGAACTCAC
GCCAGAAAGTTACATGGATTTTTAAATGCCGAGATTTTATTTTGTTTATA
AATAGAGGA
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protein sequence of SMED30000019-orf-1

>SMED30000019-orf-1 ID=SMED30000019-orf-1|Name=SMED30000019-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=276bp
MHNIFVKLNQKKIQPIYVAAVSLFLSTKYQDKRIEMKLLVEKVLILGKLS
PSKNLKIEYYITCLEHTVIGLFGTIMNMIHPNFFIKKVHNKYKFDDDFIC
SVSFICTSILHYTDFVIQYNSEYVAIIAIYIATKWNYIDLVKYDHKHWFQ
FIDPSIQTTKIIDLSHHFLKVFKEIPNNLKVIAFEQKVKENSSMLANNNI
NNNNNQNPKKRKIISKDEYTKRSQETNYSNYRAVEHKTKTNSTISSSSQF
HPQKRSDLNRPESKLELTPESYMDF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0006357regulation of transcription from RNA polymerase II promoter
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0006366transcription from RNA polymerase II promoter
GO:0006368transcription elongation from RNA polymerase II promoter
GO:0006468protein phosphorylation
GO:0007049cell cycle
GO:0007519skeletal muscle tissue development
GO:0019085early viral transcription
GO:0019086late viral transcription
GO:0042795snRNA transcription from RNA polymerase II promoter
GO:0045737positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045944positive regulation of transcription from RNA polymerase II promoter
GO:0051147regulation of muscle cell differentiation
GO:0051301cell division
GO:0016032viral process
GO:1901409positive regulation of phosphorylation of RNA polymerase II C-terminal domain
Vocabulary: cellular component
TermDefinition
GO:0042025host cell nucleus
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005737cytoplasm
GO:0005829cytosol
GO:0005886plasma membrane
GO:0008024cyclin/CDK positive transcription elongation factor complex
GO:0048471perinuclear region of cytoplasm
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR043198Cyclin/Ssn8
IPR036915Cyclin-like_sf
IPR013763Cyclin-like
Vocabulary: molecular function
TermDefinition
GO:0001223transcription coactivator binding
GO:0003682chromatin binding
GO:0004674protein serine/threonine kinase activity
GO:0005515protein binding
GO:0016538cyclin-dependent protein serine/threonine kinase regulator activity
GO:0019901protein kinase binding
GO:0070063RNA polymerase binding
GO:00973227SK snRNA binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:1.10.472.10coord: 79..193
e-value: 4.0E-16
score: 61.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 255..269
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 233..275
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 233..254
NoneNo IPR availablePANTHERPTHR10026:SF51CYCLIN-Tcoord: 1..260
IPR043198Cyclin/Cyclin-like subunit Ssn8PANTHERPTHR10026CYCLINcoord: 1..260
IPR036915Cyclin-like superfamilySUPERFAMILYSSF47954Cyclin-likecoord: 80..177